enadoline and u-50488
enadoline has been researched along with u-50488 in 14 studies
Research
Studies (14)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (78.57) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ferguson, DM; Larson, DL; Paterlini, MG; Portoghese, PS; Subramanian, G | 1 |
| Bidlack, JM; Gu, XH; Hilbert, JE; Knapp, BI; Mello, NK; Negus, SS; Neumeyer, JL; Xiong, W; Zhang, A | 1 |
| Benicourt, C; Junien, JL; Lockhart, BP; Privat, A; Soulard, P | 1 |
| Martin, BR; Smith, PB; Welch, SP | 1 |
| Picker, MJ | 1 |
| Headley, PM; Herrero, JF | 1 |
| Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ | 1 |
| Rothe, KS; Stevens, CW | 1 |
| Boudinot, E; Denavit-Saubié, M; Foutz, AS; Kieffer, BL; Maldonado, R; Matthes, HW; Negri, L; Roques, BP; Severini, C; Smadja, C; Valverde, O; Vonesch, JL | 1 |
| Black, D; Trevethick, M | 1 |
| Broqua, P; Dahl, SG; Rivière, PJ; Rocher, MN; Wettstein, JG | 1 |
| Holtzman, SG; Powell, KR | 1 |
| Hahn, B; Shoaib, M; Stolerman, IP | 1 |
| Barrett, AC; Cook, CD; Picker, MJ; Roach, EL; Syvanthong, C; Terner, JM | 1 |
Other Studies
14 other study(ies) available for enadoline and u-50488
| Article | Year |
|---|---|
Conformational analysis and automated receptor docking of selective arylacetamide-based kappa-opioid agonists.
Topics: Acetamides; Binding Sites; Ligands; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Receptors, Opioid, kappa; Structure-Activity Relationship | 1998 |
Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors.
Topics: Animals; CHO Cells; Cricetinae; Dimerization; Drug Design; Humans; Ligands; Morphinans; Radioligand Assay; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 2003 |
Distinct neuroprotective profiles for sigma ligands against N-methyl-D-aspartate (NMDA), and hypoxia-mediated neurotoxicity in neuronal culture toxicity studies.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzofurans; Brain Ischemia; Cell Death; Cells, Cultured; Dizocilpine Maleate; Hypoxia; Kainic Acid; Ligands; N-Methylaspartate; Neurons; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Phencyclidine; Receptors, sigma | 1995 |
Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzofurans; Dronabinol; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Naltrexone; Pyrrolidines; Receptors, Opioid, kappa | 1994 |
Discriminative stimulus and response rate-decreasing effects of kappa opioids: antagonism by naloxone.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzofurans; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Female; Naloxone; Narcotics; Pyrrolidines; Receptors, Opioid, kappa | 1994 |
Functional evidence for multiple receptor activation by kappa-ligands in the inhibition of spinal nociceptive reflexes in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Anticonvulsants; Benzeneacetamides; Benzofurans; Blood Pressure; Decerebrate State; Male; Naloxone; Nociceptors; Piperazines; Pyrroles; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord; Thiophenes | 1993 |
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Benzofurans; Benzomorphans; Cyclazocine; Fentanyl; Gastric Emptying; Intestinal Pseudo-Obstruction; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peritoneum; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1997 |
Supraspinal administration of opioids with selectivity for mu-, delta- and kappa-opioid receptors produces analgesia in amphibians.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzofurans; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Fentanyl; Injections, Intraventricular; Male; Morphine; Naltrexone; Narcotics; Pyrrolidines; Rana pipiens; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1997 |
Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu-receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Arrhythmia Agents; Benzofurans; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; GTP-Binding Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Oligopeptides; Pain Measurement; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Respiration; Signal Transduction; Vas Deferens | 1998 |
The kappa opioid receptor is associated with the perception of visceral pain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdominal Pain; Analgesics, Opioid; Animals; Benzofurans; Humans; Mice; Mice, Knockout; Morphine; Nociceptors; Pyrrolidines; Receptors, Opioid, kappa | 1998 |
The discriminative stimulus properties of U50,488 and morphine are not shared by fedotozine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzofurans; Benzyl Compounds; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; Morphine; Propylamines; Pyrrolidines; Rats; Rats, Long-Evans; Receptors, Opioid, kappa | 1998 |
Differential antagonism of the rate-decreasing effects of kappa-opioid receptor agonists by naltrexone and norbinaltorphimine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Benzofurans; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Ethylketocyclazocine; Nalorphine; Naltrexone; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Reinforcement Schedule; Saimiri; Thiophenes | 1999 |
Kappa-opioid receptor modulation of nicotine-induced behaviour.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Benzeneacetamides; Benzofurans; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Motor Activity; Naltrexone; Nicotine; Nicotinic Agonists; Pyrrolidines; Rats; Receptors, Opioid, kappa | 2000 |
Sex and rat strain determine sensitivity to kappa opioid-induced antinociception.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzofurans; Benzomorphans; Female; Male; Nalorphine; Narcotics; Pyrrolidines; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sex Characteristics | 2002 |