emodin has been researched along with stilbenes in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 20 (38.46) | 29.6817 |
| 2010's | 25 (48.08) | 24.3611 |
| 2020's | 7 (13.46) | 2.80 |
| Authors | Studies |
|---|---|
| Bagchi, D; Das, DK; Maulik, G; Sato, M | 1 |
| Harima, S; Kageura, T; Matsuda, H; Morikawa, T; Toguchida, I; Yoshikawa, M | 1 |
| Xue, L | 1 |
| Shang, XY; Yuan, ZB | 1 |
| Bech-Otschir, D; Berse, M; Dubiel, W; Dumdey, R; Henklein, P; Huang, X; Medalia, O; Schade, R; Sperling, J; Uhle, S; Waldron, R | 1 |
| Kim, SI; Lee, CH; Lee, KB; Ryu, SY; Song, KS; Yoo, YC | 1 |
| Li, SL; Liu, ZL; Song, ZQ; Zhang, L | 1 |
| Cui, HH; Kang, YH; Li, RM; Wang, ZQ; Wang, ZY | 1 |
| Chu, X; Liu, R; Sun, A | 1 |
| Chen, B; Miao, JR; Yang, HM; Zeng, JG | 1 |
| Ma, YT; Song, LK; Wan, DG | 1 |
| Lü, TS; Yao, QQ; Zhang, ZG | 1 |
| Ding, Y; Liu, D; Tang, HF; Yang, CE; Zhang, SQ | 1 |
| Leung, KS; Leung, SY; Lu, G; Qian, G | 1 |
| Kang, YH; Li, RM; Ma, WW; Wang, ZQ; Wang, ZY | 1 |
| Jiao, XW; Yan, P; Zhang, XN; Zhao, SJ; Zhao, X | 1 |
| Li, GK; Wang, JX; Xiao, XH | 1 |
| Dong, Y; Wang, H; Xiu, ZL | 1 |
| Dong, X; Ma, S; Zhang, T; Zhuang, X | 1 |
| Gindro, K; Godard, S; Slacanin, I; Viret, O | 1 |
| Bartůnková, K; Frantík, T; Koblihová, H; Kovárová, M; Prchalová, K; Vosátka, M | 1 |
| Chang, KW; Jeon, JG; Kim, JE; Kwon, YR; Pandit, S; Son, KJ | 1 |
| Shao, LJ; Wang, JN | 1 |
| Bartůňková, K; Frantík, T; Koblihová, H; Kovářová, M; Nývltová, Z; Vosátka, M | 1 |
| Li, N; Mao, XJ; Wang, J; Wang, MJ; Xie, J; Yu, J; Zhao, RH; Zhaori, GT | 1 |
| Chen, X; Fang, D; Huang, Q; Li, G; Wu, X; Zhang, G | 1 |
| Jeon, JG; Kim, HJ; Pandit, S; Park, SH | 1 |
| Chu, PM; Hou, YC; Lin, SP; Tsai, SY; Wu, MH | 1 |
| Hu, DY; Jin, LH; Liang, N; Wei, XH; Xue, W; Yang, S; Yang, SJ | 1 |
| Deng, T; He, YS; Li, CL; Li, HJ; Li, P; Ma, J; Zheng, L | 1 |
| Chang, YX; Gao, XM; He, J; Li, J; Ma, WF; Zhang, BL; Zhang, L; Zhang, P; Zheng, F | 1 |
| Chen, H; Cuerrier, A; Ji, X; Kelly, G; Tuck, T; Zhang, J; Zhou, X | 1 |
| Cross, NA; Haywood-Small, SL; Jordan-Mahy, N; Le Maitre, CL; Mahbub, AA; McDougall, GJ | 1 |
| Chang, CM; Chen, BY; Chen, JH; Deng, TS; Kuo, CH; Liu, YC; Shieh, CJ | 1 |
| Gu, W; He, Y; Li, Y; Lin, P; Sun, R; Wang, W; Yu, J; Zhao, R | 1 |
| Jones, PJ; Li, S; Marquardt, RR; Omar, JM; Yang, H | 1 |
| He, YS; Li, HJ; Ma, J; Zheng, L | 1 |
| Cao, F; Cen, Y; Jiang, W; Li, B; Li, X; Liu, M; Pan, X; Peng, W; Qin, R; Xiao, K; Yan, Z; Zhou, H | 1 |
| Li, J; Li, ZF; Zhang, J; Zhang, S; Zhou, R | 1 |
| Fan, YX; Jiang, LL; Li, HJ; Li, P; Luo, N; Ma, J; Yu, Q | 1 |
| Bai, ZF; Cui, HR; Guo, YM; He, LZ; Li, CY; Li, PY; Li, RY; Meng, YK; Niu, M; Sang, XX; Sun, R; Wang, JB; Wang, Y; Xiao, XH; Yin, P; Zhang, CE; Zhang, YM | 1 |
| Chen, L; Gu, X; Huang, J; Li, F; Sun, C; Wang, CZ; Yao, D; Yuan, CS; Zhang, L; Zhang, Y | 1 |
| Choi, S; Kang, KS; Kim, SH; Lee, D; Park, S | 1 |
| Chang, Y; Chen, Y; Du, KZ; He, J; Li, J; Tang, G; Tian, F | 1 |
| Gao, X; Han, L; Hu, L; Wang, C; Wang, L; Xing, Y; Yang, W; Zhang, Y | 1 |
| Li, C; Li, R; Liu, X; Liu, Y; Song, D; Tu, C; Wang, J; Wang, X; Xiao, X; Zhang, L; Zhou, Y; Zhu, J | 1 |
| Dej-Adisai, S; Heemman, A; Hong, BN; Jeong, SY; Kang, TH; Kim, NW; Nam, YH; Nuankaew, W; Shim, JH; Wattanapiromsakul, C; Yasmin, T | 1 |
| Feng, YM; Kong, WS; Li, ZC; Tao, LY; Xie, RF; Zhou, G; Zhou, X | 1 |
| Ji, X; Lai, YS; Li, D; Lyu, Y; Song, Q; Zuo, Z | 1 |
| Chen, G; Huang, C; Li, H; Li, X; Lin, H; Pan, W; Qian, W; Wei, S; Xu, Y; Yang, T; Zhao, S; Zhu, L | 1 |
| Fang, Z; Feng, D; Zhang, P | 1 |
| Dong, L; Li, W; Peng, Y; Wang, X; Zhao, G; Zheng, J | 1 |
3 review(s) available for emodin and stilbenes
| Article | Year |
|---|---|
[Progress in the pharmacological study of Chinese herbal drug: polygonum cuspidatum].
Topics: Animals; Antineoplastic Agents, Phytogenic; Antiviral Agents; Cardiotonic Agents; Drugs, Chinese Herbal; Emodin; Glucosides; Plants, Medicinal; Platelet Aggregation Inhibitors; Polygonum; Stilbenes | 2000 |
Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Apigenin; Artemisinins; Drugs, Chinese Herbal; Emodin; Flavanones; Glucuronates; Humans; Medicine, Chinese Traditional; Pancreas; Pancreatitis; Patient Safety; Phytotherapy; Plant Extracts; Pyrazines; Resveratrol; Rheum; Salvia miltiorrhiza; Stilbenes; Sulfates | 2017 |
The melanin inhibitory effect of plants and phytochemicals: A systematic review.
Topics: Acetates; Acrolein; Animals; Arbutin; Bleaching Agents; Cell Line, Tumor; Curcumin; Emodin; Flavonoids; Ginsenosides; Glucosides; Humans; Hydroxybenzoates; Melanins; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Phytochemicals; Plant Extracts; Pterocarpans; Stilbenes; Transcription Factors | 2022 |
49 other study(ies) available for emodin and stilbenes
| Article | Year |
|---|---|
Myocardial protection by protykin, a novel extract of trans-resveratrol and emodin.
Topics: Animals; Antioxidants; Blood Pressure; Coronary Vessels; Emodin; Fluoresceins; Free Radical Scavengers; Gamma Rays; Hydroxyl Radical; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Oxidative Stress; Peroxides; Polygonaceae; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes | 2000 |
Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.
Topics: Anthraquinones; Emodin; Gallic Acid; Glucosides; Lipopolysaccharides; Macrophage Activation; Macrophages; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Plant Extracts; Plants, Medicinal; Rheum; Stilbenes; Structure-Activity Relationship | 2000 |
[Determination of six effective components in Rheum by cyclodextrin modified micellar electrokinetic chromatography].
Topics: Anthraquinones; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Emodin; Plants, Medicinal; Quality Control; Rheum; Stilbenes | 2002 |
Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome.
Topics: Adenosine Triphosphate; Casein Kinase II; COP9 Signalosome Complex; Curcumin; Dichlororibofuranosylbenzimidazole; DNA-Binding Proteins; Emodin; Enzyme Inhibitors; Erythrocytes; HeLa Cells; Humans; Multiprotein Complexes; Peptide Hydrolases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Subunits; Proteins; Proto-Oncogene Proteins c-jun; Recombinant Proteins; Resveratrol; Signal Transduction; Stilbenes; Substrate Specificity; Tumor Suppressor Protein p53; Ubiquitins | 2003 |
Neuraminidase inhibitors from Reynoutria elliptica.
Topics: Drugs, Chinese Herbal; Emodin; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Neuraminidase; Polygonaceae; Resveratrol; Stilbenes; Structure-Activity Relationship | 2003 |
[Influence of process methods on contents of chemical component Radix Polygoni Multiflori].
Topics: Emodin; Glucosides; Hot Temperature; Plant Roots; Plants, Medicinal; Polygonum; Stilbenes; Tannins; Technology, Pharmaceutical | 2005 |
[Study on the optimal harvesting time of Rumex gmelini by analyzing the contents of principal components].
Topics: Anthraquinones; Emodin; Glucosides; Plant Roots; Plants, Medicinal; Principal Component Analysis; Quality Control; Resveratrol; Rumex; Seasons; Stilbenes | 2005 |
Preparative isolation and purification of five compounds from the Chinese medicinal herb Polygonum cuspidatum Sieb. et Zucc by high-speed counter-current chromatography.
Topics: Anthracenes; Chromatography, High Pressure Liquid; Countercurrent Distribution; Emodin; Fallopia japonica; Glucosides; Glycosides; Molecular Structure; Plant Preparations; Reproducibility of Results; Resveratrol; Stilbenes | 2005 |
[Simultaneous determination of resveratrol, emodin, chrysophanol, physcion, in root of Polygonam cuspidatum and its extract by HPLC].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Plant Roots; Plants, Medicinal; Quality Control; Resveratrol; Stilbenes | 2006 |
[HPLC fingerprint of Rhizoma Polygoni Cuspidati].
Topics: Chromatography, High Pressure Liquid; Emodin; Fallopia japonica; Glucosides; Plants, Medicinal; Quality Control; Reproducibility of Results; Resveratrol; Rhizome; Stilbenes; Technology, Pharmaceutical | 2006 |
[Effect of preparation on the major chemical constituents of Polygonum multiflorum].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Ethanol; Glucosides; Hot Temperature; Plant Tubers; Plants, Medicinal; Polygonum; Stilbenes; Technology, Pharmaceutical; Time Factors | 2006 |
[Application of macroporous resin in purification for effective part from Polygonum cuspidatum].
Topics: Adsorption; Anthraquinones; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Plants, Medicinal; Resins, Synthetic; Resveratrol; Stilbenes; Technology, Pharmaceutical; Temperature | 2007 |
Optimization and validation of a chromatographic method for the simultaneous quantification of six bioactive compounds in Rhizoma et Radix Polygoni Cuspidati.
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Molecular Structure; Reproducibility of Results; Resveratrol; Rhizome; Stilbenes; Technology, Pharmaceutical | 2008 |
[Study on correlation of soil nutrients and content of active constituents in root of Rumex gmelini].
Topics: Anthraquinones; Ecosystem; Emodin; Fertilizers; Glucosides; Nitrogen; Phosphorus; Plant Roots; Plants, Medicinal; Potassium; Regression Analysis; Resveratrol; Rumex; Soil; Stilbenes | 2007 |
[Comparison of content of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside and anthraquinon in different ploidy Radix Polygoni Multiflori].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Emodin; Glucosides; Plant Roots; Plants, Medicinal; Ploidies; Polygonum; Reproducibility of Results; Stilbenes | 2007 |
Study of vacuum microwave-assisted extraction of polyphenolic compounds and pigment from Chinese herbs.
Topics: Chemical Fractionation; Coloring Agents; Coumaric Acids; Drugs, Chinese Herbal; Emodin; Flavonoids; Glucosides; Microwaves; Myrica; Phenols; Plant Leaves; Polyphenols; Quercetin; Reproducibility of Results; Resveratrol; Stilbenes; Vacuum | 2008 |
Microwave-assisted aqueous two-phase extraction of piceid, resveratrol and emodin from Polygonum cuspidatum by ethanol/ammonium sulphate systems.
Topics: Acetonitriles; Ammonium Sulfate; Chromatography, High Pressure Liquid; Emodin; Ethanol; Fallopia japonica; Glucosides; Microwaves; Plant Extracts; Resveratrol; Stilbenes | 2008 |
Selective on-line extraction of trans-resveratrol and emodin from Polygonum cuspidatum using molecularly imprinted polymer.
Topics: Chromatography, High Pressure Liquid; Emodin; Fallopia japonica; Polymers; Resveratrol; Stilbenes | 2008 |
Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew.
Topics: Anthraquinones; Chromatography; Chromatography, High Pressure Liquid; Emodin; Mass Spectrometry; Models, Biological; Peroxidases; Plant Leaves; Plant Physiological Phenomena; Plant Roots; Reactive Oxygen Species; Resveratrol; Solvents; Stilbenes; Time Factors | 2009 |
Factors influencing the production of stilbenes by the knotweed, Reynoutria x bohemica.
Topics: Biomass; Emodin; Mycorrhizae; Nitrogen; Phosphorus; Plants, Medicinal; Polygonum; Resveratrol; Soil; Stilbenes | 2010 |
Bioactivity-guided separation of anti-acidogenic substances against Streptococcus mutans UA 159 from Polygonum cuspidatum.
Topics: Acids; Anthracenes; Cariostatic Agents; Chelating Agents; Chemical Fractionation; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Glycolysis; Glycosides; Humans; Hydrogen-Ion Concentration; Materials Testing; Phenols; Plant Extracts; Resveratrol; Sodium Fluoride; Stilbenes; Streptococcus mutans | 2010 |
[Studies on the chemical constituents of radix Boehmeriae].
Topics: Boehmeria; Catechin; Chromatography; Emodin; Glucosides; Magnetic Resonance Spectroscopy; Nitrates; Plant Roots; Potassium Compounds; Stilbenes | 2010 |
Effect of clone selection, nitrogen supply, leaf damage and mycorrhizal fungi on stilbene and emodin production in knotweed.
Topics: Biomass; Emodin; Fertilizers; Mycorrhizae; Nitrogen; Plant Leaves; Polygonum; Rhizome; Seasons; Soil; Stilbenes | 2011 |
Hepatoxicity of major constituents and extractions of Radix Polygoni Multiflori and Radix Polygoni Multiflori Praeparata.
Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Cell Line; Cell Proliferation; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Emodin; Glucosides; Humans; L-Lactate Dehydrogenase; Liver; Plant Roots; Plants, Medicinal; Polygonaceae; Solvents; Stilbenes | 2011 |
Toxicity of raw and processed roots of Polygonum multiflorum.
Topics: Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Female; Glucosides; Humans; Male; Mice; Mice, Inbred Strains; Plant Roots; Polygonum; Stilbenes | 2012 |
Enhancement of fluoride activity against Streptococcus mutans biofilms by a substance separated from Polygonum cuspidatum.
Topics: Biofilms; Drug Synergism; Emodin; Fallopia japonica; Fluorides; Humans; Hydrogen-Ion Concentration; Plant Extracts; Resveratrol; Stilbenes; Streptococcus mutans; Virulence Factors | 2012 |
Pharmacokinetics and tissue distribution of resveratrol, emodin and their metabolites after intake of Polygonum cuspidatum in rats.
Topics: Animals; Brain; Emodin; Fallopia japonica; Glucuronides; Kidney; Liver; Lung; Male; Myocardium; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Rhizome; Stilbenes; Tissue Distribution | 2012 |
Chemical constituents of Caesalpinia decapetala (Roth) Alston.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Benzopyrans; Benzyl Alcohols; Biphenyl Compounds; Caesalpinia; Cell Line, Tumor; Cell Survival; Emodin; Flavonoids; Free Radical Scavengers; Free Radicals; Glucosides; Humans; Inhibitory Concentration 50; Molecular Structure; Picrates; Plant Extracts; Stilbenes; Triterpenes | 2013 |
Stilbene glucoside inhibits the glucuronidation of emodin in rats through the down-regulation of UDP-glucuronosyltransferases 1A8: application to a drug-drug interaction study in Radix Polygoni Multiflori.
Topics: Animals; Down-Regulation; Drug Interactions; Emodin; Glucosides; Glucuronides; Glucuronosyltransferase; Intestinal Mucosa; Liver; Male; Plant Extracts; Plant Roots; Polygonum; Rats; Rats, Wistar; RNA, Messenger; Stilbenes | 2013 |
Influence of processing on pharmacokinetic of typical constituents in radix polygoni multiflori after oral administration by LC-ESI-MS/MS.
Topics: Animals; Chromatography, Liquid; Drugs, Chinese Herbal; Emodin; Gallic Acid; Glucosides; Male; Medicine, Chinese Traditional; Models, Biological; Plant Roots; Polygonum; Rats; Rats, Sprague-Dawley; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry | 2013 |
Quality assessment of Japanese knotweed (Fallopia japonica) grown on Prince Edward Island as a source of resveratrol.
Topics: Antioxidants; Emodin; Fallopia japonica; Glucosides; Plant Leaves; Plant Roots; Plant Stems; Plant Weeds; Prince Edward Island; Quality Control; Resveratrol; Stilbenes | 2013 |
Differential effects of polyphenols on proliferation and apoptosis in human myeloid and lymphoid leukemia cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Emodin; Humans; Inhibitory Concentration 50; Lymphocytes; Molecular Structure; Myeloid Cells; Organ Specificity; Quercetin; Stereoisomerism; Stilbenes; Structure-Activity Relationship | 2013 |
Optimized ultrasound-assisted extraction of phenolic compounds from Polygonum cuspidatum.
Topics: Emodin; Fallopia japonica; Glucosides; Phenols; Plant Extracts; Resveratrol; Solvents; Sound; Stilbenes; Temperature | 2013 |
In vitro effects of active components of Polygonum Multiflorum Radix on enzymes involved in the lipid metabolism.
Topics: Cell Line; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Diacylglycerol O-Acyltransferase; Emodin; Fatty Liver; Glucosides; Humans; Hydroxymethylglutaryl CoA Reductases; Plant Roots; Polygonum; Stilbenes; Triglycerides | 2014 |
Development of an improved reverse-phase high-performance liquid chromatography method for the simultaneous analyses of trans-/cis-resveratrol, quercetin, and emodin in commercial resveratrol supplements.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Dietary Supplements; Emodin; Isomerism; Quercetin; Resveratrol; Stilbenes | 2014 |
Hepatotoxic assessment of Polygoni Multiflori Radix extract and toxicokinetic study of stilbene glucoside and anthraquinones in rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Emodin; Glucosides; Liver; Male; Plant Extracts; Plant Roots; Polygonum; Rats, Sprague-Dawley; Stilbenes; Toxicokinetics | 2015 |
Emodin is identified as the active component of ether extracts from Rhizoma Polygoni Cuspidati, for anti-MRSA activity.
Topics: Anti-Bacterial Agents; Cell Membrane; Cell Wall; Drugs, Chinese Herbal; Emodin; Glucosides; Methicillin-Resistant Staphylococcus aureus; Resveratrol; Rhizome; Stilbenes | 2015 |
Enhanced absorption and inhibited metabolism of emodin by 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside: Possible mechanisms for Polygoni Multiflori Radix-induced liver injury.
Topics: Caco-2 Cells; Chemical and Drug Induced Liver Injury; Emodin; Fallopia multiflora; Glucosides; Glucuronosyltransferase; Humans; Plant Roots; Stilbenes | 2017 |
Cis-stilbene glucoside in Polygonum multiflorum induces immunological idiosyncratic hepatotoxicity in LPS-treated rats by suppressing PPAR-γ.
Topics: Animals; Chemical and Drug Induced Liver Injury; Emodin; Fallopia multiflora; Glucosides; Lipopolysaccharides; Male; Microarray Analysis; NF-kappa B; Pioglitazone; Plant Roots; PPAR gamma; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stereoisomerism; Stilbenes; Thiazolidinediones | 2017 |
A surface magnetic imprinted polymers as artificial receptors for selective and efficient capturing of new neuronal nitric oxide synthase-post synaptic density protein-95 uncouplers.
Topics: Animals; Cell Line, Tumor; Disks Large Homolog 4 Protein; Emodin; Glucosides; Magnetics; Molecular Imprinting; Neuroprotective Agents; Nitric Oxide Synthase Type I; PC12 Cells; Polymers; Post-Synaptic Density; Rats; Receptors, Artificial; Solid Phase Extraction; Solvents; Stilbenes | 2018 |
In Vitro Estrogenic and Breast Cancer Inhibitory Activities of Chemical Constituents Isolated from Rheum undulatum L.
Topics: Anthraquinones; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Emodin; Estrogen Receptor alpha; Estrogens; Female; Fulvestrant; Glucosides; Humans; Molecular Structure; Plant Extracts; Plant Roots; Rheum; Stilbenes; Structure-Activity Relationship | 2018 |
Quantification of eight active ingredients in crude and processed radix polygoni multiflori applying miniaturized matrix solid-phase dispersion microextraction followed by UHPLC.
Topics: Catechin; Chromatography, High Pressure Liquid; Emodin; Fallopia multiflora; Gallic Acid; Glucosides; Particle Size; Solid Phase Microextraction; Stilbenes; Surface Properties | 2018 |
Pharmacokinetic studies unveiled the drug-drug interaction between trans-2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucopyranoside and emodin that may contribute to the idiosyncratic hepatotoxicity of Polygoni Multiflori Radix.
Topics: Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Disease Models, Animal; Drug Interactions; Drugs, Chinese Herbal; Emodin; Glucosides; Humans; Male; Plant Roots; Polygonum; Rats; Rats, Sprague-Dawley; Stilbenes; Tandem Mass Spectrometry | 2019 |
Components synergy between stilbenes and emodin derivatives contributes to hepatotoxicity induced by
Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Interactions; Drugs, Chinese Herbal; Emodin; Fallopia multiflora; Humans; Medicine, Chinese Traditional; Rats; Stilbenes | 2020 |
Anti-insulin resistance effect of constituents from Senna siamea on zebrafish model, its molecular docking, and structure-activity relationships.
Topics: alpha-Glucosidases; Animals; Anthraquinones; Diabetes Mellitus; Dipeptidyl Peptidase 4; Emodin; Hypoglycemic Agents; Insulin Resistance; Molecular Docking Simulation; Molecular Structure; Plant Extracts; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Resveratrol; Senna Plant; Stilbenes; Structure-Activity Relationship; Thailand; Wood; Zebrafish | 2021 |
Fingerprinting and Determination of Hepatotoxic Constituents in Polygoni Multiflori Radix Praeparata of Different Producing Places by HPLC.
Topics: China; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Gallic Acid; Glycosides; Plant Roots; Stilbenes | 2022 |
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside enhances the hepatotoxicity of emodin in vitro and in vivo.
Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Drug-Related Side Effects and Adverse Reactions; Emodin; Glucosides; Rats; Stilbenes | 2022 |
Radix polygoni multiflori protects against hippocampal neuronal apoptosis in diabetic encephalopathy by inhibiting the HDAC4/JNK pathway.
Topics: Animals; Apoptosis; Brain Diseases; Diabetes Mellitus, Experimental; Emodin; Hippocampus; Histone Deacetylases; MAP Kinase Signaling System; Rats; Stilbenes | 2022 |
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside, a mechanism-based inactivator of CYP2C19 and CYP3A4, potentiates hepatic protein adduction and hepatotoxicity induced by emodin in vivo.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Emodin; Glucosides; Humans; Mice; Stilbenes | 2022 |