emodin and apigenin

emodin has been researched along with apigenin in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.70)18.2507
2000's10 (43.48)29.6817
2010's10 (43.48)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Chang, CJ; Geahlen, RL1
Abou-Shoer, M; Chang, CJ; Geahlen, RL; Koonchanok, NM; Li, XH; Ma, GE1
Strassburg, CP; Tukey, RH1
Bain, J; Battistutta, R; de Moliner, E; Elliott, M; Fabbro, D; Furet, P; Meggio, F; Pagano, MA; Pinna, LA; Ruzzene, M; Sarno, S; Schoepfer, J; Zanotti, G1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Hirasawa, A; Kinoshita, T; Kitaura, K; Nakanishi, I; Nakaniwa, T; Sekiguchi, Y; Tada, T; Tsujimoto, G1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Arioka, S; Hinou, H; Nishimura, S; Sakagami, M; Takemoto, H; Togame, H; Uematsu, R; Yamaguchi, H1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Hirasawa, A; Iwamoto, N; Kinoshita, T; Kitaura, K; Kurono, M; Miyazaki, T; Murata, K; Nagata, N; Nakamura, S; Nakanishi, I; Nakaniwa, T; Nishiwaki, K; Sakurai, A; Sekiguchi, Y; Takei, Y; Tsujimoto, G; Yasue, M1
Dutour, R; Poirier, D1
Golonko, A; Lazny, R; Lewandowski, W; Pienkowski, T; Roszko, M; Swislocka, R1
Chen, T; Chen, Y; Feng, F; Guo, Q; Lin, H; Liu, W; Liu, Z; Qiao, Y; Qu, W; Sun, H; Yang, H1
Channavajhala, P; Seldin, DC1
Liang, NC; Liu, XG; Zhu, F1
Adachi, T; Fujii, S; Hirasawa, A; Kadowaki, T; Katsuma, S; Kobayashi, M; Koshimizu, TA; Miyamoto, Y; Nihei, H; Okuno, Y; Sekiya, Y; Shiojima, S; Tamura, M; Tsujimoto, G; Yamada, M; Yumura, W1
Hui, TT; Li, ZM; Rao, GX; Sun, Y; Xue, YM; Zhang, QL1
Hui, TT; Rao, GX; Wang, WJ; Xue, YM; Zhang, QL1
Tai, ZF; Wang, F; Zhang, GL1
Dong, D; Ma, Z; Wang, H; Wang, Y; Wu, B; Zhang, X1
Mu, S; Sun, L; Wang, X; Wei, L; Yu, Z1
Li, J; Li, ZF; Zhang, J; Zhang, S; Zhou, R1
He, L; He, W; Li, N; Liao, Y; Mai, B; Mai, X; Mao, P; Zhang, Q; Zheng, L1

Reviews

6 review(s) available for emodin and apigenin

ArticleYear
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Inhibitors of cytochrome P450 (CYP) 1B1.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship

2017
Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Animals; Diet; Humans; Neoplasms; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Ubiquitin

2019
Small molecule modulators targeting protein kinase CK1 and CK2.
    European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

    Topics: Animals; Casein Kinase I; Casein Kinase II; Drug Discovery; Humans; Molecular Docking Simulation; Protein Kinase Inhibitors; Small Molecule Libraries

2019
Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis.
    World journal of gastroenterology, 2017, May-28, Volume: 23, Issue:20

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Apigenin; Artemisinins; Drugs, Chinese Herbal; Emodin; Flavanones; Glucuronates; Humans; Medicine, Chinese Traditional; Pancreas; Pancreatitis; Patient Safety; Phytotherapy; Plant Extracts; Pyrazines; Resveratrol; Rheum; Salvia miltiorrhiza; Stilbenes; Sulfates

2017

Other Studies

17 other study(ies) available for emodin and apigenin

ArticleYear
Flavonoids from Koelreuteria henryi and other sources as protein-tyrosine kinase inhibitors.
    Journal of natural products, 1993, Volume: 56, Issue:6

    Topics: Animals; Cattle; Flavonoids; Kaempferols; Magnetic Resonance Spectroscopy; Plant Extracts; Plants; Protein-Tyrosine Kinases; Quercetin

1993
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).
    The Biochemical journal, 2003, Sep-15, Volume: 374, Issue:Pt 3

    Topics: Acetates; Animals; Casein Kinase II; Cell Line; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Jurkat Cells; Molecular Structure; Plant Proteins; Protein Serine-Threonine Kinases; Protein Structure, Quaternary; Quinazolines; Rats; Zea mays

2003
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid.
    Bioorganic & medicinal chemistry letters, 2009, Jun-01, Volume: 19, Issue:11

    Topics: Adenosine Triphosphate; Binding Sites; Casein Kinase II; Catalytic Domain; Crystallography, X-Ray; Ellagic Acid; Enzyme Inhibitors; Humans; Protein Structure, Tertiary

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase.
    Bioorganic & medicinal chemistry, 2010, Feb-15, Volume: 18, Issue:4

    Topics: Base Sequence; DNA Primers; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glycoproteins; Neuraminidase; Recombinant Proteins; Structure-Activity Relationship; Trypanosoma cruzi

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Identification of protein kinase CK2 inhibitors using solvent dipole ordering virtual screening.
    European journal of medicinal chemistry, 2015, Volume: 96

    Topics: Casein Kinase II; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Activation; Humans; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Solvents; Structure-Activity Relationship

2015
Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis.
    Oncogene, 2002, Aug-08, Volume: 21, Issue:34

    Topics: Animals; Apigenin; Blotting, Western; Casein Kinase II; Cell Division; Cells, Cultured; Emodin; Flavonoids; Glutathione Transferase; Lymphoma; Mice; Mice, Transgenic; Peptide Hydrolases; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Recombinant Fusion Proteins; T-Lymphocytes

2002
[Effect of emodin and apigenin on invasion of human ovarian carcinoma HO-8910PM cells in vitro].
    Ai zheng = Aizheng = Chinese journal of cancer, 2003, Volume: 22, Issue:4

    Topics: Antineoplastic Agents; Apigenin; Collagenases; Drug Screening Assays, Antitumor; Emodin; Female; Flavonoids; Humans; Neoplasm Invasiveness; Ovarian Neoplasms; Tumor Cells, Cultured

2003
Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, May-24, Volume: 102, Issue:21

    Topics: Analysis of Variance; Animals; Apigenin; Blood Urea Nitrogen; Blotting, Western; Casein Kinase II; Creatinine; Emodin; Glomerulonephritis; Immune Sera; Immunohistochemistry; In Situ Nick-End Labeling; Kidney; Male; Oligodeoxyribonucleotides, Antisense; Oligonucleotide Array Sequence Analysis; Prednisolone; Protein Subunits; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Specific Pathogen-Free Organisms

2005
[Studies on chemical constituents from rattan of Polygonum multiflorum].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:8

    Topics: Anthraquinones; Apigenin; Emodin; Glucosides; Molecular Structure; Plant Stems; Plants, Medicinal; Polygonum; Sitosterols; Spectrophotometry, Ultraviolet

2008
[Studies on the chemical constituents of the leaves of Polygonum multiflorum].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2009, Volume: 32, Issue:6

    Topics: Apigenin; Emodin; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Polygonum; Rutin; Sitosterols

2009
Identification of small molecule activators of the janus kinase/signal transducer and activator of transcription pathway using a cell-based screen.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:1

    Topics: Antiviral Agents; Apigenin; Drug Evaluation, Preclinical; Emodin; Flavonoids; Gene Expression; Genes, Reporter; Hep G2 Cells; Humans; Interferon Type I; Janus Kinases; Luteolin; Plant Extracts; Quercetin; Response Elements; Signal Transduction; STAT Transcription Factors; Virus Diseases

2012
Stable knock-down of efflux transporters leads to reduced glucuronidation in UGT1A1-overexpressing HeLa cells: the evidence for glucuronidation-transport interplay.
    Molecular pharmaceutics, 2015, Apr-06, Volume: 12, Issue:4

    Topics: Apigenin; Base Sequence; Chromatography, High Pressure Liquid; DNA Primers; Emodin; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genistein; Glucuronides; Glucuronosyltransferase; HeLa Cells; Humans; Hydrolysis; Kinetics; Lentivirus; Molecular Sequence Data; Protein Transport; RNA, Small Interfering; Transfection

2015
Ultra high performance liquid chromatography with electrospray ionization tandem mass spectrometry coupled with hierarchical cluster analysis to evaluate Wikstroemia indica (L.) C. A. Mey. from different geographical regions.
    Journal of separation science, 2015, Volume: 38, Issue:12

    Topics: Apigenin; Chromatography, High Pressure Liquid; Cluster Analysis; Coumarins; Emodin; Flavones; Furans; Geography; Lignans; Medicine, Chinese Traditional; Plant Extracts; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Umbelliferones; Wikstroemia

2015
Antipyretic Mechanism Exploration of HuanglianShangqing Pill Based on Metabolomics and Network Pharmacology.
    Combinatorial chemistry & high throughput screening, 2022, Volume: 25, Issue:12

    Topics: 3-Hydroxybutyric Acid; Acetaminophen; Animals; Antipyretics; Apigenin; Berberine; Citrates; Drugs, Chinese Herbal; Emodin; Ibuprofen; Interleukin-6; Kaempferols; Luteolin; Metabolomics; Network Pharmacology; Rats; Succinates

2022