Page last updated: 2024-09-03

efegatran and hirudin

efegatran has been researched along with hirudin in 10 studies

Compound Research Comparison

Studies
(efegatran)
Trials
(efegatran)
Recent Studies (post-2010)
(efegatran)
Studies
(hirudin)
Trials
(hirudin)
Recent Studies (post-2010) (hirudin)
43303,658378995

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (70.00)18.2507
2000's3 (30.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Callas, DD; Fareed, J1
Callas, DD; Fareed, J; Hoppensteadt, D1
Bacher, P; Bajusz, S; Breddin, K; Fareed, J; Iqbal, O; Walenga, JM1
Callas, D; Fareed, J; Iqbal, O1
Kleiman, NS1
Verstraete, M1
Deinum, J; Elg, M; Gustafsson, D1
Adams, TE; Everse, SJ; Mann, KG1
Green, L; Li, W; Singh, JP; Tarzami, ST; Wang, G1

Reviews

3 review(s) available for efegatran and hirudin

ArticleYear
Clinical trials of conjunctive anticoagulant strategies in thrombolysis.
    Coronary artery disease, 1996, Volume: 7, Issue:7

    Topics: Anticoagulants; Antithrombins; Arginine; Blood Platelets; Clinical Trials as Topic; Epoprostenol; Heparin; Hirudin Therapy; Hirudins; Humans; Myocardial Infarction; Oligopeptides; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recombinant Proteins; Sulfonamides; Thrombin; Thrombolytic Therapy

1996
Modulating platelet function with selective thrombin inhibitors.
    Haemostasis, 1996, Volume: 26 Suppl 4

    Topics: Administration, Oral; Adult; Animals; Antithrombins; Arginine; Blood Platelets; Boron Compounds; Clinical Trials as Topic; Dogs; Drug Evaluation, Preclinical; Glycine; Hirudin Therapy; Hirudins; Humans; Naphthalenes; Oligopeptides; Peptide Fragments; Pipecolic Acids; Piperidines; Recombinant Proteins; Sulfonamides; Thrombin

1996
Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data.
    Lancet (London, England), 2002, Jan-26, Volume: 359, Issue:9303

    Topics: Angina, Unstable; Antithrombins; Arginine; Glycine; Heparin; Hirudin Therapy; Hirudins; Humans; Myocardial Infarction; Oligopeptides; Peptide Fragments; Pipecolic Acids; Piperidines; Randomized Controlled Trials as Topic; Recombinant Proteins; Sulfonamides; Survival Rate; Thrombin

2002

Other Studies

7 other study(ies) available for efegatran and hirudin

ArticleYear
Direct inhibition of protein Ca by site directed thrombin inhibitors: implications in anticoagulant and thrombolytic therapy.
    Thrombosis research, 1995, Jun-01, Volume: 78, Issue:5

    Topics: Antifibrinolytic Agents; Antithrombin III; Antithrombins; Aprotinin; Arginine; Binding Sites; Boron Compounds; Enzyme Activation; Fibrinolysis; Heparin; Hirudins; Humans; Oligopeptides; Peptide Fragments; Pipecolic Acids; Protein C; Recombinant Proteins; Sulfonamides; Thrombin

1995
Comparative studies on the anticoagulant and protease generation inhibitory actions of newly developed site-directed thrombin inhibitory drugs. Efegatran, argatroban, hirulog, and hirudin.
    Seminars in thrombosis and hemostasis, 1995, Volume: 21, Issue:2

    Topics: Amino Acid Sequence; Anticoagulants; Antithrombins; Arginine; Endopeptidases; Feedback; Hirudins; Humans; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides

1995
The antithrombotic and anticoagulant effects of a synthetic tripeptide and recombinant hirudin in various animal models.
    Thrombosis research, 1993, Aug-15, Volume: 71, Issue:4

    Topics: Amino Acid Sequence; Animals; Anticoagulants; Blood Coagulation; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hirudin Therapy; Hirudins; Jugular Veins; Molecular Sequence Data; Oligopeptides; Rabbits; Recombinant Proteins; Thrombosis

1993
Comparison of the anticoagulant activities of thrombin inhibitors as assessed by thromboelastographic analysis.
    Seminars in thrombosis and hemostasis, 1995, Volume: 21 Suppl 4

    Topics: Amino Acid Sequence; Anticoagulants; Antithrombins; Blood Coagulation; Drug Evaluation, Preclinical; Hirudins; Humans; Molecular Sequence Data; Oligopeptides; Recombinant Proteins; Thrombelastography; Thrombin; Thromboplastin

1995
The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis.
    Thrombosis and haemostasis, 1997, Volume: 78, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Arginine; Azetidines; Benzylamines; Carotid Artery Thrombosis; Dose-Response Relationship, Drug; Fibrinolytic Agents; Glycine; Hemodynamics; Heparin; Hirudin Therapy; Hirudins; Kinetics; Male; Oligopeptides; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Piperidines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfonamides; Thrombin; Thrombin Time

1997
Predicting the pharmacology of thrombin inhibitors.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:5

    Topics: Anticoagulants; Arginine; Azetidines; Benzylamines; Blood Coagulation; Computer Simulation; Dose-Response Relationship, Drug; Glycine; Hirudins; Humans; Kinetics; Models, Cardiovascular; Oligopeptides; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin

2003
Thrombin and PAR-1 stimulate differentiation of bone marrow-derived endothelial progenitor cells.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:3

    Topics: Animals; Antigens, CD; Bone Marrow Cells; Cadherins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Hirudins; Mice; Mice, Inbred C57BL; Oligopeptides; Receptor, PAR-1; Stem Cells; Thrombin

2006