efegatran and hirudin
efegatran has been researched along with hirudin in 10 studies
Compound Research Comparison
| Studies (efegatran) | Trials (efegatran) | Recent Studies (post-2010) (efegatran) | Studies (hirudin) | Trials (hirudin) | Recent Studies (post-2010) (hirudin) |
|---|---|---|---|---|---|
| 43 | 3 | 0 | 3,658 | 378 | 995 |
Research
Studies (10)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Callas, DD; Fareed, J | 1 |
| Callas, DD; Fareed, J; Hoppensteadt, D | 1 |
| Bacher, P; Bajusz, S; Breddin, K; Fareed, J; Iqbal, O; Walenga, JM | 1 |
| Callas, D; Fareed, J; Iqbal, O | 1 |
| Kleiman, NS | 1 |
| Verstraete, M | 1 |
| Deinum, J; Elg, M; Gustafsson, D | 1 |
| Adams, TE; Everse, SJ; Mann, KG | 1 |
| Green, L; Li, W; Singh, JP; Tarzami, ST; Wang, G | 1 |
Reviews
3 review(s) available for efegatran and hirudin
| Article | Year |
|---|---|
Clinical trials of conjunctive anticoagulant strategies in thrombolysis.
Topics: Anticoagulants; Antithrombins; Arginine; Blood Platelets; Clinical Trials as Topic; Epoprostenol; Heparin; Hirudin Therapy; Hirudins; Humans; Myocardial Infarction; Oligopeptides; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Recombinant Proteins; Sulfonamides; Thrombin; Thrombolytic Therapy | 1996 |
Modulating platelet function with selective thrombin inhibitors.
Topics: Administration, Oral; Adult; Animals; Antithrombins; Arginine; Blood Platelets; Boron Compounds; Clinical Trials as Topic; Dogs; Drug Evaluation, Preclinical; Glycine; Hirudin Therapy; Hirudins; Humans; Naphthalenes; Oligopeptides; Peptide Fragments; Pipecolic Acids; Piperidines; Recombinant Proteins; Sulfonamides; Thrombin | 1996 |
Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data.
Topics: Angina, Unstable; Antithrombins; Arginine; Glycine; Heparin; Hirudin Therapy; Hirudins; Humans; Myocardial Infarction; Oligopeptides; Peptide Fragments; Pipecolic Acids; Piperidines; Randomized Controlled Trials as Topic; Recombinant Proteins; Sulfonamides; Survival Rate; Thrombin | 2002 |
Other Studies
7 other study(ies) available for efegatran and hirudin
| Article | Year |
|---|---|
Direct inhibition of protein Ca by site directed thrombin inhibitors: implications in anticoagulant and thrombolytic therapy.
Topics: Antifibrinolytic Agents; Antithrombin III; Antithrombins; Aprotinin; Arginine; Binding Sites; Boron Compounds; Enzyme Activation; Fibrinolysis; Heparin; Hirudins; Humans; Oligopeptides; Peptide Fragments; Pipecolic Acids; Protein C; Recombinant Proteins; Sulfonamides; Thrombin | 1995 |
Comparative studies on the anticoagulant and protease generation inhibitory actions of newly developed site-directed thrombin inhibitory drugs. Efegatran, argatroban, hirulog, and hirudin.
Topics: Amino Acid Sequence; Anticoagulants; Antithrombins; Arginine; Endopeptidases; Feedback; Hirudins; Humans; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides | 1995 |
The antithrombotic and anticoagulant effects of a synthetic tripeptide and recombinant hirudin in various animal models.
Topics: Amino Acid Sequence; Animals; Anticoagulants; Blood Coagulation; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hirudin Therapy; Hirudins; Jugular Veins; Molecular Sequence Data; Oligopeptides; Rabbits; Recombinant Proteins; Thrombosis | 1993 |
Comparison of the anticoagulant activities of thrombin inhibitors as assessed by thromboelastographic analysis.
Topics: Amino Acid Sequence; Anticoagulants; Antithrombins; Blood Coagulation; Drug Evaluation, Preclinical; Hirudins; Humans; Molecular Sequence Data; Oligopeptides; Recombinant Proteins; Thrombelastography; Thrombin; Thromboplastin | 1995 |
The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Arginine; Azetidines; Benzylamines; Carotid Artery Thrombosis; Dose-Response Relationship, Drug; Fibrinolytic Agents; Glycine; Hemodynamics; Heparin; Hirudin Therapy; Hirudins; Kinetics; Male; Oligopeptides; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Piperidines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfonamides; Thrombin; Thrombin Time | 1997 |
Predicting the pharmacology of thrombin inhibitors.
Topics: Anticoagulants; Arginine; Azetidines; Benzylamines; Blood Coagulation; Computer Simulation; Dose-Response Relationship, Drug; Glycine; Hirudins; Humans; Kinetics; Models, Cardiovascular; Oligopeptides; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin | 2003 |
Thrombin and PAR-1 stimulate differentiation of bone marrow-derived endothelial progenitor cells.
Topics: Animals; Antigens, CD; Bone Marrow Cells; Cadherins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Hirudins; Mice; Mice, Inbred C57BL; Oligopeptides; Receptor, PAR-1; Stem Cells; Thrombin | 2006 |