edaravone and riluzole

edaravone has been researched along with riluzole in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (36.36)24.3611
2020's14 (63.64)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Kiernan, MC; Noto, Y; Shibuya, K; Vucic, S1
Scott, A1
Rothstein, JD1
Babu, RJ; Dash, RP; Srinivas, NR1
Jaiswal, MK1
Schultz, J1
Gendron, TF; Oskarsson, B; Staff, NP1
Barp, A; Gerardi, F; Lizio, A; Lunetta, C; Sansone, VA1
Chen, JJ1
Eslahchi, C; Ghassempour, A; Kiaei, M; Sadr, AS1
Chen, S; Gao, Y; Le, W; Meng, H; Ni, Y; Shen, D; Shi, H; Xu, X; Zhou, Q1
Başak, AN; Ciftci, H; DeMirci, H; Fujita, M; Ocak, F; Otsuka, M; Sever, B; Sever, H; Tateishi, H; Tateishi, T; Yulug, B1
Gautam, M; Genç, B; Goshu, GM; Günay, A; Hande Ozdinler, P; Helmold, BR; Koçak, N; Silverman, RB1
Bassani, D; Federico, S; Moro, S; Pavan, M; Spalluto, G; Sturlese, M1
Beland, B; Chhibber, S; Frost, GS; Hodgkinson, V; Jewett, G; Khayambashi, S; Korngut, L; Lee, A1
Berry, JD; De Marchi, F; Fang, T; Johnson, SA; Neel, D; Paganoni, S; Van Weehaeghe, D1
Borges, F; Chavarria, D; Oliveira, PJ; Silva, C; Silva, FSG; Soares, P1
Carreira, RB; Costa, SL; da Silva, VDA; de Oliveira, JVR; de Oliveira, LMG; do Nascimento, RP; Dos Santos Souza, C; Trias, E1
Ogino, M1
Lynch, K1
Aksinenko, AY; Bachurin, SO; Dubrovskaya, ES; Epishina, TA; Fisenko, VP; Goreva, TV; Grigoriev, VV; Lapshina, MA; Makhaeva, GF; Maleev, GV; Shevtsova, EF; Steinberg, DA; Ustyugov, AA; Veselov, IM; Vinogradova, DV; Zamoyski, VL1

Reviews

12 review(s) available for edaravone and riluzole

ArticleYear
Novel therapies in development that inhibit motor neuron hyperexcitability in amyotrophic lateral sclerosis.
    Expert review of neurotherapeutics, 2016, Volume: 16, Issue:10

    Topics: Amyotrophic Lateral Sclerosis; Antipyrine; Edaravone; Humans; Motor Neurons; Neuroprotective Agents; Riluzole

2016
Two Decades-Long Journey from Riluzole to Edaravone: Revisiting the Clinical Pharmacokinetics of the Only Two Amyotrophic Lateral Sclerosis Therapeutics.
    Clinical pharmacokinetics, 2018, Volume: 57, Issue:11

    Topics: Administration, Intravenous; Administration, Oral; Amyotrophic Lateral Sclerosis; Brain; Edaravone; Humans; Neuroprotective Agents; Riluzole

2018
Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs.
    Medicinal research reviews, 2019, Volume: 39, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Disease Progression; Drug Design; Edaravone; Humans; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Riluzole

2019
Disease-modifying treatment of amyotrophic lateral sclerosis.
    The American journal of managed care, 2018, Volume: 24, Issue:15 Suppl

    Topics: Amyotrophic Lateral Sclerosis; Edaravone; Humans; Neuroprotective Agents; Quality of Life; Riluzole

2018
Amyotrophic Lateral Sclerosis: An Update for 2018.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:11

    Topics: Amyotrophic Lateral Sclerosis; C9orf72 Protein; Diagnosis, Differential; Edaravone; Female; Humans; Male; Mesenchymal Stem Cell Transplantation; Neuroprotective Agents; Riluzole

2018
Emerging Drugs for the Treatment of Amyotrophic Lateral Sclerosis: A Focus on Recent Phase 2 Trials.
    Expert opinion on emerging drugs, 2020, Volume: 25, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Progression; Drug Development; Drug Discovery; Edaravone; Humans; Neuroprotective Agents; Oxidative Stress; Riluzole

2020
A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?
    Translational neurodegeneration, 2021, 08-10, Volume: 10, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Clinical Trials as Topic; Disease Management; Disease Progression; Edaravone; Free Radical Scavengers; Humans; Neuroprotective Agents; Riluzole; Stem Cell Transplantation

2021
Comprehensive Research on Past and Future Therapeutic Strategies Devoted to Treatment of Amyotrophic Lateral Sclerosis.
    International journal of molecular sciences, 2022, Feb-22, Volume: 23, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Combined Modality Therapy; Deep Brain Stimulation; Drug Discovery; Edaravone; Humans; Induced Pluripotent Stem Cells; Riluzole

2022
The Multifaceted Role of GPCRs in Amyotrophic Lateral Sclerosis: A New Therapeutic Perspective?
    International journal of molecular sciences, 2022, Apr-19, Volume: 23, Issue:9

    Topics: Amyotrophic Lateral Sclerosis; Edaravone; Humans; Motor Neurons; Receptors, G-Protein-Coupled; Riluzole

2022
Pharmacotherapy for Amyotrophic Lateral Sclerosis: A Review of Approved and Upcoming Agents.
    Drugs, 2022, Volume: 82, Issue:13

    Topics: Amyotrophic Lateral Sclerosis; Biological Products; Clinical Trials as Topic; Disease Progression; Edaravone; Humans; Neuroprotective Agents; Riluzole

2022
Drug discovery and amyotrophic lateral sclerosis: Emerging challenges and therapeutic opportunities.
    Ageing research reviews, 2023, Volume: 83

    Topics: Amyotrophic Lateral Sclerosis; Drug Discovery; Edaravone; Humans; Oxidative Stress; Riluzole

2023
Impact of Plant-Derived Compounds on Amyotrophic Lateral Sclerosis.
    Neurotoxicity research, 2023, Volume: 41, Issue:3

    Topics: Amyotrophic Lateral Sclerosis; Edaravone; Glutamic Acid; Humans; Phytochemicals; Riluzole

2023

Other Studies

10 other study(ies) available for edaravone and riluzole

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Drug therapy: On the treatment trail for ALS.
    Nature, 2017, 10-18, Volume: 550, Issue:7676

    Topics: Amyotrophic Lateral Sclerosis; Antipyrine; Benzamides; C9orf72 Protein; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; Edaravone; Genetic Therapy; Humans; Imidazoles; Mesenchymal Stem Cells; Motor Neurons; Neuroglia; Off-Label Use; Oligoribonucleotides, Antisense; Piperidines; Precision Medicine; Pyrazines; Pyridines; Riluzole; RNAi Therapeutics; Stem Cell Transplantation; Superoxide Dismutase; Thiazoles; United States; United States Food and Drug Administration

2017
Edaravone: A new drug approved for ALS.
    Cell, 2017, Nov-02, Volume: 171, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Antipyrine; Drug Approval; Edaravone; Excitatory Amino Acid Antagonists; Humans; Riluzole

2017
Overview of current and emerging therapies for amytrophic lateral sclerosis.
    The American journal of managed care, 2020, Volume: 26, Issue:9 Suppl

    Topics: Amyotrophic Lateral Sclerosis; Antibodies, Monoclonal, Humanized; Benzamides; Edaravone; Humans; Mesenchymal Stem Cells; Oligonucleotides; Piperidines; Pyridines; Riluzole; Thiazoles

2020
In silico studies reveal structural deviations of mutant profilin-1 and interaction with riluzole and edaravone in amyotrophic lateral sclerosis.
    Scientific reports, 2021, 03-25, Volume: 11, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Computer Simulation; Edaravone; Humans; Molecular Docking Simulation; Mutant Proteins; Mutation; Neuroprotective Agents; Profilins; Protein Conformation; Riluzole

2021
NU-9 improves health of hSOD1
    Scientific reports, 2022, 03-30, Volume: 12, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Animals; Edaravone; Humans; Mice; Motor Neurons; Riluzole; Superoxide Dismutase

2022
Gold Coast criteria expand clinical trial eligibility in amyotrophic lateral sclerosis.
    Muscle & nerve, 2022, Volume: 66, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Clinical Trials as Topic; Edaravone; Eligibility Determination; Humans; Retrospective Studies; Riluzole

2022
[Drugs for Amyotrophic Lateral Sclerosis].
    Brain and nerve = Shinkei kenkyu no shinpo, 2023, Volume: 75, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Edaravone; Humans; Japan; Neuroprotective Agents; Riluzole

2023
Optimizing pharmacologic treatment for ALS to improve outcomes and quality of life.
    The American journal of managed care, 2023, Volume: 29, Issue:7 Suppl

    Topics: Amyotrophic Lateral Sclerosis; Edaravone; Humans; Quality of Life; Riluzole

2023
New Adamantane-Containing Edaravone Conjugates as Potential Neuroprotective Agents for ALS Treatments.
    Molecules (Basel, Switzerland), 2023, Nov-13, Volume: 28, Issue:22

    Topics: Adamantane; Amantadine; Amyotrophic Lateral Sclerosis; Edaravone; Humans; Neuroprotective Agents; Riluzole

2023
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