diclofenac and mk 0663

diclofenac has been researched along with mk 0663 in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	33 (51.56)	29.6817
2010's	24 (37.50)	24.3611
2020's	7 (10.94)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Bockow, B; Curtis, S; DeTora, L; Fisher, C; Geissler, L; Gertz, BJ; Gottesdiener, K; Ko, A; Markenson, J; Schnitzer, T	1
Frölich, JC; Stichtenoth, DO	1
Feldman, D; Gerli, R; Hou, SM; Ozturk, ZE; Rodger, IW; Scott, D; Uebelhart, D; Zacher, J	1
Bretschneider, E; Censarek, P; Fischer, JW; Meyer-Kirchrath, J; Pape, R; Rabausch, K; Sarbia, M; Schrör, K; Weber, AA	1
Hochberg, MC	1
Bockow, B; Compton, A; Curtis, SP; Fisher, C; Ko, AT; Olaleye, J; Reicin, AS	1
Giezek, H; Grifka, J; Hupli, M; Maini, M; Morales, R; Nilganuwong, S; Ozturk, ZE; Shivaprakash, M; Zerbini, C	1
Geisslinger, G; Manderscheid, C; Niederberger, E	1
Bolognese, JA; Cannon, CP; Curtis, SP; Laine, L	1
Patrignani, P; Rodríguez, LA	1
Bolognese, JA; Bombardier, C; Cannon, CP; Curtis, SP; Erdmann, E; FitzGerald, GA; Kaur, A; Krum, H; Laine, L; Reicin, AS; van der Heijde, D; Weinblatt, ME	1
Psaty, BM; Weiss, NS	1
Bolognese, JA; Cavanaugh, PF; Curtis, SP; Ko, AT; Reicin, AS	1
Cannon, CP; Cryer, B; Curtis, SP; Kaur, A; Laine, L	2
Baraf, HS; Bird, S; Brzezicki, J; Curtis, SP; Fuentealba, C; Greenwald, M; Kaur, A; O'Brien, K; Polis, A; Soffer, B	1
Jick, H; Jick, SS; Kaye, JA	1
Einecke, D	2
Parashar, A	1
Ashcroft, DM; Chen, LC	1
Krüger, K	1
Baraf, HS	1
Hunt, RH; Yuan, Y	1
Bhattacharyya, TK; Das, N; Ghosh, S; Paul, S	1
Curtis, S; Dore, R; Kaur, A; Krueger, K; Lino, L; Radominski, S; Simpson, R; Zhang, Y	1
Klotz, U; Shi, S	1
Cavanaugh, PF; Chappell, DL; Dallob, AL; Flynn, ME; Hilliard, DA; Larson, PJ; Laterza, OF; Miller, J; Royalty, J; Schwartz, JI; Snyder, KM; Wagner, JA	1
Cannon, CP; Cryer, B; Curtis, SP; Jensen, DM; Kaur, A; Laine, L; Langman, M	1
Cannon, CP; Connors, LG; Curtis, SP; Goldkind, L; Laine, L; Yanqiong, Z	1
Cannon, CP; Combe, B; Connors, L; Curtis, S; Emery, P; Kaur, A; Laine, L; McCarthy, T; McLay, J; Swergold, G; Zerbini, C	1
Brater, DC; Cannon, CP; Curtis, SP; Kaur, A; Krum, H; Laine, L; Smugar, SS; Wang, H; Weir, MR	1
Brater, DC; Cannon, CP; Curtis, SP; Kaur, A; Krum, H; Laine, L; Smugar, SS; Swergold, G; Wang, H; Weir, MR	1
Choy, EH; Gaugris, S; Jansen, JP; Nash, JT; Ostor, A; Stam, W	1
Elliott, WJ	1
Alekseeva, LI	1
Honjo, H; Iwamoto, K; Uwai, Y	1
Brune, K; Cannon, CP; Contant, CF; Curtis, SP; Jarolim, P; Kaur, A; Laine, L; Morrow, DA; Ren, F; Ruff, CT	1
Micu, MC; Micu, R; Ostensen, M	1
Brater, DC; Cannon, CP; Curtis, SP; Gammaitoni, A; Kaur, A; Krum, H; Laine, L; Peloso, PM; Smugar, SS; Swergold, G; Wang, H; Weir, MR	1
Carrillo-Alarcón, LC; Izquierdo-Vega, JA; Loo-Estrada, JJ; Monroy-Maya, R; Ortiz, MI; Ponce-Monter, HA; Rangel-Flores, E; Sánchez-Gutiérrez, M; Soto-Ríos, M	1
Angioni, C; Felden, L; Ferreiros, N; Geisslinger, G; Lötsch, J; Schreiber, Y; von Hentig, N; Walter, C	1
Hu, RW; Li, HY; Li, JS; Miao, XP; Ouyang, Q; Zhang, Y	1
Liu, P; Ma, JL; Wang, J; Zhang, S; Zhang, W; Zhang, Y	1
Barta, S; Craiovan, B; Grifka, J; Kehl, V; Schröter, C; Springorum, HR; Wagner, F; Winkler, SH	1
Hansen, SH; Skonberg, C; Syed, M	1
Barta, S; Craiovan, B; Grifka, J; Handel, M; Kehl, V; Springorum, HR; Vaitl, T; Winkler, S	1
Davydkin, IL; Zolotovskaya, IA	1
Ghanghas, P; Jain, S; Rana, C; Sanyal, SN	2
Akhverdyan, YR; Polyakova, JV; Sivordova, LE; Zavodovsky, BV	1
Feng, X; Mei, H; Tian, M; Zhang, W	1
Chiou, JY; Huang, YK; Peijer Hsieh, J; Peng, YS; Ting, HF; Wang, YH; Wei, JC; Xue, YH	1
Arfè, A; Castellsague, J; Garbe, E; Herings, R; Kollhorst, B; Lucchi, S; Masclee, GMC; Perez-Gutthann, S; Romio, S; Schade, R; Schink, T; Schuemie, MJ; Scotti, L; Straatman, H; Sturkenboom, MCJM; Valkhoff, VE; Varas-Lorenzo, C; Villa, M	1
Alibrandi, A; Dalessandri, D; Isola, G; Matarese, G; Migliorati, M; Pedullà, E; Rapisarda, E	1
Li, M; Yu, C; Zeng, X	1
Aziz, ND; Murtadha Al-Shehristani, RM	1
Ding, X; Li, X; Lu, N; Wang, Y; Wu, Z	1
Andrade, JP; Dourado, M; Lira, L; Marques, D; Napoleão, L; Ribeiro, H; Rodrigues, I; Veríssimo, M	1
Hjemdahl, P; Stiller, CO	1
Pedersen, L; Schmidt, M; Sørensen, HT	1
Gorbach, T; Koiro, O; Kudina, O; Shtrygol, S; Tovchiga, O; Yudkevich, T	1

Reviews

16 review(s) available for diclofenac and mk 0663

Article	Year
The second generation of COX-2 inhibitors: what advantages do the newest offer? Drugs, 2003, Volume: 63, Issue:1 Topics: Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Etoricoxib; Humans; Isoenzymes; Isoxazoles; Membrane Proteins; Organic Chemicals; Prostaglandin-Endoperoxide Synthases; Pyridines; Sulfonamides; Sulfones	2003
COX-2 selective inhibitors in the treatment of arthritis: a rheumatologist perspective. Current topics in medicinal chemistry, 2005, Volume: 5, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cost-Benefit Analysis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Etoricoxib; Humans; Isoxazoles; Lactones; Membrane Proteins; Organic Chemicals; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Randomized Controlled Trials as Topic; Rheumatology; Sulfonamides; Sulfones; Treatment Outcome	2005
Pooled analysis of thrombotic cardiovascular events in clinical trials of the COX-2 selective Inhibitor etoricoxib. Current medical research and opinion, 2006, Volume: 22, Issue:12 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Osteoarthritis; Pyridines; Randomized Controlled Trials as Topic; Sulfones; Thrombosis	2006
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Lancet (London, England), 2007, Feb-10, Volume: 369, Issue:9560 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Etoricoxib; Female; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Osteoarthritis; Peptic Ulcer; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Pyridines; Sulfones	2007
Risk of myocardial infarction associated with selective COX-2 inhibitors: meta-analysis of randomised controlled trials. Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib; Humans; Isoxazoles; Lactones; Models, Statistical; Myocardial Infarction; Naproxen; Odds Ratio; Pyrazoles; Pyridines; Randomized Controlled Trials as Topic; Risk; Risk Factors; Sulfonamides; Sulfones	2007
Efficacy of the newest COX-2 selective inhibitors in rheumatic disease. Current pharmaceutical design, 2007, Volume: 13, Issue:22 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Gastrointestinal Hemorrhage; Humans; Membrane Proteins; Osteoarthritis; Patient Selection; Pyridines; Rheumatic Diseases; Risk Assessment; Risk Factors; Spondylitis, Ankylosing; Sulfones	2007
Global gastrointestinal safety profile of etoricoxib and lumiracoxib. Current pharmaceutical design, 2007, Volume: 13, Issue:22 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Interactions; Endoscopy, Gastrointestinal; Etoricoxib; Humans; Occult Blood; Patient Selection; Peptic Ulcer; Peptic Ulcer Hemorrhage; Pyridines; Risk Assessment; Risk Factors; Sulfones	2007
Clinical use and pharmacological properties of selective COX-2 inhibitors. European journal of clinical pharmacology, 2008, Volume: 64, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Monitoring; Etoricoxib; Humans; Osteoarthritis; Pain; Pyrazoles; Pyridines; Sulfonamides; Sulfones	2008
Do the blood pressure effects of nonsteroidal antiinflammatory drugs influence cardiovascular morbidity and mortality? Current hypertension reports, 2010, Volume: 12, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Hypertension; Isoxazoles; Lactones; Pyrazoles; Pyridines; Risk; Risk Factors; Sulfonamides; Sulfones	2010
[Comparative evaluation of the safety and efficacy of etoricoxib and diclofenac on the upper gastrointestinal tract in patients with osteoarthrosis and rheumatoid arthritis (the multinational etoricoxib and diclofenac arthritis long-term (MEDAL) study pro Terapevticheskii arkhiv, 2010, Volume: 82, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Etoricoxib; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Osteoarthritis; Pyridines; Randomized Controlled Trials as Topic; Sulfones; Treatment Outcome	2010
Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease. The Cochrane database of systematic reviews, 2014, Oct-23, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colitis, Ulcerative; Crohn Disease; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Isoxazoles; Lactones; Pyrazoles; Pyridines; Randomized Controlled Trials as Topic; Safety-Based Drug Withdrawals; Sulfonamides; Sulfones	2014
Efficacy and safety of etoricoxib compared with NSAIDs in acute gout: a systematic review and a meta-analysis. Clinical rheumatology, 2016, Volume: 35, Issue:1 Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Gout; Humans; Indomethacin; Pain Measurement; Pyridines; Randomized Controlled Trials as Topic; Sulfones; Treatment Outcome	2016
Gastrointestinal safety of etoricoxib in osteoarthritis and rheumatoid arthritis: A meta-analysis. PloS one, 2018, Volume: 13, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Naproxen; Osteoarthritis; Pyridines; Randomized Controlled Trials as Topic; Sulfones	2018
Comparative efficacy of traditional non-selective NSAIDs and selective cyclo-oxygenase-2 inhibitors in patients with acute gout: a systematic review and meta-analysis. BMJ open, 2020, 09-10, Volume: 10, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; China; Diclofenac; Etoricoxib; Gout; Humans	2020
Non-steroidal anti-inflammatory drugs (NSAIDs), pain and aging: Adjusting prescription to patient features. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 150 Topics: Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Pain; Prescriptions	2022
Lessons from 20 years with COX-2 inhibitors: Importance of dose-response considerations and fair play in comparative trials. Journal of internal medicine, 2022, Volume: 292, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Fibrinolytic Agents; Humans; Ibuprofen; Lactones; Naproxen; Prostaglandins; Prostaglandins I; Sulfones; Thromboxanes	2022

Trials

22 trial(s) available for diclofenac and mk 0663

Article	Year
Results of a randomized, dose-ranging trial of etoricoxib in patients with osteoarthritis. Rheumatology (Oxford, England), 2002, Volume: 41, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Etoricoxib; Female; Health Status; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Pliability; Pyridines; Severity of Illness Index; Sulfones; Treatment Outcome	2002
A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis. Current medical research and opinion, 2003, Volume: 19, Issue:8 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pyridines; Sulfones; Treatment Outcome; United States	2003
Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489]. BMC musculoskeletal disorders, 2005, Dec-01, Volume: 6 Topics: Administration, Oral; Aged; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Etoricoxib; Female; Humans; Male; Middle Aged; Osteoarthritis; Pyridines; Sulfones; Treatment Outcome	2005
Efficacy of etoricoxib 60 mg/day and diclofenac 150 mg/day in reduction of pain and disability in patients with chronic low back pain: results of a 4-week, multinational, randomized, double-blind study. Current medical research and opinion, 2005, Volume: 21, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Diclofenac; Double-Blind Method; Etoricoxib; Female; Humans; Low Back Pain; Male; Middle Aged; Pyridines; Sulfones	2005
Gastrointestinal side effects of etoricoxib in patients with osteoarthritis: results of the Etoricoxib versus Diclofenac Sodium Gastrointestinal Tolerability and Effectiveness (EDGE) trial. The Journal of rheumatology, 2007, Volume: 34, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Osteoarthritis; Pyridines; Sulfones; Treatment Outcome; Withholding Treatment	2007
A study on the effects of diclofenac sodium and etoricoxib in the treatment of osteoarthritis. Journal of the Indian Medical Association, 2007, Volume: 105, Issue:5 Topics: Adult; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pyridines; Sulfones; Treatment Outcome	2007
Gastrointestinal tolerability of etoricoxib in rheumatoid arthritis patients: results of the etoricoxib vs diclofenac sodium gastrointestinal tolerability and effectiveness trial (EDGE-II). Annals of the rheumatic diseases, 2008, Volume: 67, Issue:3 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Pyridines; Sulfones; Treatment Outcome	2008
Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects. Journal of clinical pharmacology, 2008, Volume: 48, Issue:6 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Double-Blind Method; Etoricoxib; Female; Humans; Male; Middle Aged; Pyrazoles; Pyridines; Sulfonamides; Sulfones; Thromboxane B2	2008
Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2 selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory drug diclofenac. Gastroenterology, 2008, Volume: 135, Issue:5 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Confidence Intervals; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Incidence; Male; Middle Aged; Odds Ratio; Osteoarthritis; Prospective Studies; Pyridines; Risk Factors; Sulfones; Treatment Outcome	2008
How common is diclofenac-associated liver injury? Analysis of 17,289 arthritis patients in a long-term prospective clinical trial. The American journal of gastroenterology, 2009, Volume: 104, Issue:2 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cohort Studies; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Female; Hospitalization; Humans; Liver Diseases; Male; Middle Aged; Osteoarthritis; Pyridines; Risk Factors; Sulfones	2009
Cardiovascular safety and gastrointestinal tolerability of etoricoxib vs diclofenac in a randomized controlled clinical trial (The MEDAL study). Rheumatology (Oxford, England), 2009, Volume: 48, Issue:4 Topics: Aged; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Emergencies; Etoricoxib; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Odds Ratio; Osteoarthritis; Pyridines; Safety; Sample Size; Sulfones; Thrombosis	2009
Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program. European journal of heart failure, 2009, Volume: 11, Issue:6 Topics: Aged; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Etoricoxib; Female; Follow-Up Studies; Heart Failure; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Prognosis; Proportional Hazards Models; Pyridines; Retrospective Studies; Risk Factors; Sulfones	2009
Factors associated with blood pressure changes in patients receiving diclofenac or etoricoxib: results from the MEDAL study. Journal of hypertension, 2009, Volume: 27, Issue:4 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Pressure; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Osteoarthritis; Pyridines; Sulfones	2009
Risk factors for NSAID-associated upper GI clinical events in a long-term prospective study of 34 701 arthritis patients. Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Pyridines; Risk Factors; Sulfones; Time Factors; Upper Gastrointestinal Tract	2010
Blood pressure and cardiovascular outcomes in patients taking nonsteroidal antiinflammatory drugs. Cardiovascular therapeutics, 2012, Volume: 30, Issue:6 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Blood Pressure; Body Weight; Comorbidity; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Female; Heart Failure; Humans; Male; Middle Aged; Prospective Studies; Pyridines; Racial Groups; Risk Assessment; Sulfones; Thrombosis	2012
Effectiveness of diclofenac, ketorolac and etoricoxib in the treatment of acute pain from ankle fracture. Proceedings of the Western Pharmacology Society, 2010, Volume: 53 Topics: Acute Pain; Adult; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Etoricoxib; Fractures, Bone; Humans; Ketorolac; Middle Aged; Prospective Studies; Pyridines; Sulfones	2010
Similar maximum systemic but not local cyclooxygenase-2 inhibition by 50 mg lumiracoxib and 90 mg etoricoxib: a randomized controlled trial in healthy subjects. Pharmaceutical research, 2014, Volume: 31, Issue:7 Topics: Adult; Arachidonic Acid; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Humans; Male; Prostaglandins; Pyridines; Sulfones; Young Adult	2014
Perioperative blood loss and gastrointestinal tolerability of etoricoxib and diclofenac in total hip arthroplasty (ETO-DIC study): a single-center, prospective double-blinded randomized controlled trial. Current medical research and opinion, 2016, Volume: 32, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Female; Gastrointestinal Tract; Hemorrhage; Humans; Male; Middle Aged; Prospective Studies; Pyridines; Sulfones	2016
Comparative clinical study of the prophylaxis of heterotopic ossifications after total hip arthroplasty using etoricoxib or diclofenac. International orthopaedics, 2016, Volume: 40, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Female; Humans; Incidence; Male; Middle Aged; Ossification, Heterotopic; Pelvis; Perioperative Period; Prospective Studies; Pyridines; Sulfones	2016
[Effect of nonsteroidal anti-inflammatory drugs on the indicators of cardiovascular risk in patients with acute nonspecific back pain]. Terapevticheskii arkhiv, 2015, Volume: 87, Issue:12 Topics: Acute Pain; Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Humans; Male; Meloxicam; Middle Aged; Pyridines; Sulfonamides; Sulfones; Thiazines; Thiazoles; Treatment Outcome	2015
[Evidence of feasibility etoricoxib therapy in osteoarthritis in elderly patients]. Advances in gerontology = Uspekhi gerontologii, 2016, Volume: 29, Issue:2 Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diclofenac; Drug Monitoring; Etoricoxib; Female; Humans; Male; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Management; Pyridines; Sulfones; Treatment Outcome	2016
Comparison of Effectiveness of Etoricoxib and Diclofenac on Pain and Perioperative Sequelae After Surgical Avulsion of Mandibular Third Molars: A Randomized, Controlled, Clinical Trial. The Clinical journal of pain, 2019, Volume: 35, Issue:11 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Etoricoxib; Female; Humans; Male; Molar, Third; Pain, Postoperative; Tooth Extraction; Treatment Outcome	2019

Other Studies

26 other study(ies) available for diclofenac and mk 0663

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins. Circulation research, 2005, Jan-07, Volume: 96, Issue:1 Topics: Alprostadil; Blood Coagulation; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Coronary Vessels; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epoprostenol; Etoricoxib; Gene Expression Profiling; Gene Expression Regulation; Humans; Iloprost; Isoquinolines; Mammary Arteries; Membrane Proteins; Models, Biological; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Saphenous Vein; Second Messenger Systems; Sulfonamides; Sulfones; Tetradecanoylphorbol Acetate; Thrombomodulin; Thrombophilia; Vasodilator Agents	2005
Different COX-independent effects of the COX-2 inhibitors etoricoxib and lumiracoxib. Biochemical and biophysical research communications, 2006, Apr-14, Volume: 342, Issue:3 Topics: Animals; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Etoricoxib; Gene Expression Regulation; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Organic Chemicals; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Sulfones; Transcription Factor AP-1	2006
Clinical trial design and patient demographics of the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) study program: cardiovascular outcomes with etoricoxib versus diclofenac in patients with osteoarthritis and rheumatoid arthritis. American heart journal, 2006, Volume: 152, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Osteoarthritis; Patient Selection; Pyridines; Randomized Controlled Trials as Topic; Research Design; Risk Assessment; Sulfones; Treatment Outcome	2006
The ever growing story of cyclo-oxygenase inhibition. Lancet (London, England), 2006, Nov-18, Volume: 368, Issue:9549 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Etoricoxib; Humans; Pyridines; Randomized Controlled Trials as Topic; Sulfones	2006
Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Lancet (London, England), 2006, Nov-18, Volume: 368, Issue:9549 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Osteoarthritis; Pyridines; Randomized Controlled Trials as Topic; Sulfones	2006
NSAID trials and the choice of comparators--questions of public health importance. The New England journal of medicine, 2007, Jan-25, Volume: 356, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Clinical Trials, Phase IV as Topic; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Approval; Drug Industry; Etoricoxib; Gastrointestinal Hemorrhage; Humans; Pyridines; Sulfones; United States; United States Food and Drug Administration	2007
Cardiovascular safety of cyclo-oxygenase-2 inhibitors. Lancet (London, England), 2007, Feb-17, Volume: 369, Issue:9561 Topics: Cyclooxygenase Inhibitors; Diclofenac; Etoricoxib; Humans; Myocardial Infarction; Pyridines; Randomized Controlled Trials as Topic; Sulfones	2007
[By what means does the rheumatic patient with gastrointestinal risks fare best?]. MMW Fortschritte der Medizin, 2007, Mar-08, Volume: 149, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Controlled Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Etoricoxib; Gastrointestinal Diseases; Germany; Humans; Naproxen; Osteoarthritis; Proton Pump Inhibitors; Pyridines; Rheumatic Diseases; Risk Factors; Sulfones; United States	2007
Gastrointestinal safety of NSAIDs versus COX-2 inhibitors. Lancet (London, England), 2007, Apr-21, Volume: 369, Issue:9570 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Etoricoxib; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Pyridines; Sulfones	2007
[Coronary risks with NSAID and coxibs. The end of hysteria]. MMW Fortschritte der Medizin, 2006, Nov-30, Volume: 148, Issue:48 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Cause of Death; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Osteoarthritis; Peptic Ulcer; Prospective Studies; Pyridines; Randomized Controlled Trials as Topic; Risk; Sulfones; Thrombosis	2006
[3 questions about gastrointestinal risk. Are coxibs here clearly better than NSAID?]]. MMW Fortschritte der Medizin, 2006, Nov-30, Volume: 148, Issue:48 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Osteoarthritis; Peptic Ulcer; Prospective Studies; Pyridines; Randomized Controlled Trials as Topic; Risk; Sulfones	2006
Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDS in the treatment of ankylosing spondylitis. PharmacoEconomics, 2010, Volume: 28, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Bayes Theorem; Celecoxib; Cost-Benefit Analysis; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Costs; Drug-Related Side Effects and Adverse Reactions; Etoricoxib; Humans; Markov Chains; Meta-Analysis as Topic; Models, Economic; Naproxen; Pyrazoles; Pyridines; Quality-Adjusted Life Years; Severity of Illness Index; Spondylitis, Ankylosing; Sulfonamides; Sulfones; Treatment Outcome; United Kingdom	2010
Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3. Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:5 Topics: Animals; Binding, Competitive; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Estrone; Etoricoxib; Humans; Inhibitory Concentration 50; Isoxazoles; Kinetics; Lactones; Methotrexate; Oocytes; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Pyrazoles; Pyridines; RNA, Complementary; Sulfonamides; Sulfones; Xenopus laevis	2010
Evaluation of NT-proBNP and high sensitivity C-reactive protein for predicting cardiovascular risk in patients with arthritis taking longterm nonsteroidal antiinflammatory drugs. The Journal of rheumatology, 2011, Volume: 38, Issue:6 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Diclofenac; Etoricoxib; Female; Heart Failure; Humans; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Natriuretic Peptide, Brain; Osteoarthritis; Peptide Fragments; Prospective Studies; Pyridines; Retrospective Studies; Risk Factors; Sulfones; Thrombosis; Treatment Outcome	2011
Luteinized unruptured follicle syndrome increased by inactive disease and selective cyclooxygenase 2 inhibitors in women with inflammatory arthropathies. Arthritis care & research, 2011, Volume: 63, Issue:9 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chi-Square Distribution; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Fertility; Humans; Ibuprofen; Infertility, Female; Inflammation; Norway; Ovarian Follicle; Ovulation; Pregnancy; Prospective Studies; Pyridines; Rheumatic Diseases; Risk Assessment; Risk Factors; Sulfones; Ultrasonography	2011
Mitochondrial toxicity of selective COX-2 inhibitors via inhibition of oxidative phosphorylation (ATP synthesis) in rat liver mitochondria. Toxicology in vitro : an international journal published in association with BIBRA, 2016, Volume: 32 Topics: Adenosine Triphosphate; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Isoxazoles; Lactones; Male; Mitochondria, Liver; Oxidative Phosphorylation; Pyridines; Rats, Sprague-Dawley; Sulfonamides; Sulfones	2016
[Paracetamol in knee and hip arthrosis is dispensable]. MMW Fortschritte der Medizin, 2016, Apr-14, Volume: 158, Issue:7 Topics: Acetaminophen; Diclofenac; Etoricoxib; Humans; Naproxen; Osteoarthritis, Hip; Osteoarthritis, Knee; Pyridines; Sulfones; Treatment Outcome	2016
Chemoprevention of Colon Cancer through Inhibition of Angiogenesis and Induction of Apoptosis by Nonsteroidal Anti-Inflammatory Drugs. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2016, Volume: 35, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Celecoxib; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Neovascularization, Pathologic; Pyridines; Rats; Rats, Sprague-Dawley; Sulfones	2016
Role of GSK-3β in Regulation of Canonical Wnt/β-catenin Signaling and PI3-K/Akt Oncogenic Pathway in Colon Cancer. Cancer investigation, 2017, Aug-09, Volume: 35, Issue:7 Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Apoptosis; Celecoxib; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Glycogen Synthase Kinase 3 beta; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridines; Rats, Sprague-Dawley; Sulfones; Time Factors; Wnt Signaling Pathway	2017
Etoricoxib and Diclofenac Might Reduce the Risk of Dementia in Patients with Osteoarthritis: A Nation-Wide, Population-Based Retrospective Cohort Study. Dementia and geriatric cognitive disorders, 2018, Volume: 45, Issue:5-6 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Dementia; Diclofenac; Etoricoxib; Female; Humans; Incidence; Male; Middle Aged; Osteoarthritis; Proportional Hazards Models; Research Design; Retrospective Studies; Risk; Taiwan	2018
Risk of acute myocardial infarction during use of individual NSAIDs: A nested case-control study from the SOS project. PloS one, 2018, Volume: 13, Issue:11 Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Diclofenac; Etoricoxib; Female; Humans; Indomethacin; Ketorolac; Lactones; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Risk Factors; Sulfones	2018
The effect of etoricoxib versus diclofenac on blood pressure in hypertensive patients. JPMA. The Journal of the Pakistan Medical Association, 2021, Volume: 71(Suppl 9), Issue:12 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Humans; Hypertension; Male; Middle Aged; Pyridines; Sulfones	2021
Association between tramadol use and risk of pneumonia in the middle-aged and elderly populations: a propensity-score matched cohort study. European journal of pain (London, England), 2022, Volume: 26, Issue:6 Topics: Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Codeine; Cohort Studies; Diclofenac; Etoricoxib; Humans; Middle Aged; Naproxen; Pneumonia; Tramadol	2022
Cardiovascular Risks of Diclofenac Versus Other Older COX-2 Inhibitors (Meloxicam and Etodolac) and Newer COX-2 Inhibitors (Celecoxib and Etoricoxib): A Series of Nationwide Emulated Trials. Drug safety, 2022, Volume: 45, Issue:9 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Etodolac; Etoricoxib; Female; Heart Disease Risk Factors; Humans; Meloxicam; Risk Factors	2022
The effect of non-steroidal anti-inflammatory drugs with different mechanisms of action on the body temperature and cyclooxygenase pathway of the arachidonic acid cascade on the model of acute general cooling (air hypothermia) in rats. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2022,Fall, Volume: 71, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Body Temperature; Cyclooxygenase 2; Diclofenac; Dinoprost; Dinoprostone; Etoricoxib; Hypothermia; Rats	2022