cytarabine and glycine

cytarabine has been researched along with glycine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19909 (28.13)18.7374
1990's2 (6.25)18.2507
2000's4 (12.50)29.6817
2010's10 (31.25)24.3611
2020's7 (21.88)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bohunicky, L; Cerny, V; Halko, J; Koza, I; Krizan, Z; Petrek, C; Poliakova, L1
Loehr, EV; Roberts, D1
Chirigos, MA1
Dukes, PP; Ortega, JA1
Chae, CB; Irvin, JL; Krasny, H; Piantadosi, C; Williams, A1
Ritter, EJ1
Baker, DC; Hanvey, JC; Hardman, JK; Suhadolnik, RJ1
Rooze, M1
Kaminskas, E1
Baixerás, E; Cebrián, A; Martínez, C; Revilla, Y; Salas, ML; Viñuela, E1
Blanc, EM; Guiramand, J; Jallageas, M; Recasens, M1
Akaike, H; Kawasaki, K; Miyauchi, A; Ouchi, K1
Graves, LM; Huang, M; Leisewitz, AV; Wang, Y; Yang, J; Zimmerman, EI1
Honda, M; Nakano, T; Ono, H; Tanabe, M1
Burnett, A; Hewamana, S; Jenkins, C; Krige, D; Pepper, C1
Advani, AS; Charman, A; Cortes, J; Feldman, E; Kantarjian, H; Rizzieri, D; Spruyt, R; Toal, M; Yee, K1
Becker, PS; Dean, C; Deeg, HJ; Estey, E; Hendrie, P; Mawad, R; Myint, H; Pagel, JM; Sandhu, V; Scott, B; Singer, JW; Walter, R; Wang, L; Wood, BL1
Hu, L; Liu, M; Pan, S; Pei, L; Shang, Y; Song, L; Wu, Y; Xian, W; Xiong, W; Yao, S1
Sweet, K; Talati, C1
Tiong, IS; Wei, AH1
Advani, AS; Caimi, P; Carew, J; Carraway, H; Chan, R; Cooper, B; de Lima, M; Elson, P; Gerds, A; Hamilton, B; Kalaycio, M; Little, J; Maciejewski, J; Malek, E; Miron, A; Mukherjee, S; Nazha, A; Pink, J; Sekeres, MA; Sobecks, R; Tomlinson, B; Unger, A; Visconte, V; Wei, W1
DiNardo, C; Guerra, VA; Konopleva, M1
DiNardo, CD; Wei, AH1
Emadi, A; Estey, E; Gale, RP; Karp, JE; Othus, M1
Carraway, HE; Chandhok, NS; Griffiths, EA; Prebet, T1
Cerchione, C; Martinelli, G1
Candoni, A; Clavio, M; Dennis, M; Giannini, B; Gibellini, D; Gilkes, A; Isidori, A; Loscocco, F; Mianulli, AM; Musuraca, G; Navari, M; Piccaluga, PP; Rocchi, M; Sensi, A; Visani, G; Zuffa, E1
Ariti, C; Burnett, A; Clark, RE; Copland, M; Dennis, M; Greaves, P; Hemmaway, C; Hills, R; Russell, N; Severinsen, MT; Thomas, I1
Thol, F1

Reviews

5 review(s) available for cytarabine and glycine

ArticleYear
Recently approved therapies in acute myeloid leukemia: A complex treatment landscape.
    Leukemia research, 2018, Volume: 73

    Topics: Aminoglycosides; Aminopyridines; Antibodies, Monoclonal, Humanized; Cytarabine; Daunorubicin; Female; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Pyridines; Staurosporine; Triazines

2018
New drugs creating new challenges in acute myeloid leukemia.
    Genes, chromosomes & cancer, 2019, Volume: 58, Issue:12

    Topics: Aminopyridines; Aniline Compounds; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Pyrazines; Pyridines; Staurosporine; Triazines; United States; United States Food and Drug Administration

2019
Venetoclax-based therapies for acute myeloid leukemia.
    Best practice & research. Clinical haematology, 2019, Volume: 32, Issue:2

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Cytarabine; Daunorubicin; Glycine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Proto-Oncogene Proteins c-bcl-2; Pyridines; Sulfonamides; Triazines

2019
Recent drug approvals for newly diagnosed acute myeloid leukemia: gifts or a Trojan horse?
    Leukemia, 2020, Volume: 34, Issue:3

    Topics: Antineoplastic Agents; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Drug Approval; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Pyridines; Randomized Controlled Trials as Topic; Staurosporine; Sulfonamides; United States; United States Food and Drug Administration

2020
Advances in non-intensive chemotherapy treatment options for adults diagnosed with acute myeloid leukemia.
    Leukemia research, 2020, Volume: 91

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Phenylurea Compounds; Precision Medicine; Pyridines; Recurrence; Remission Induction; Staurosporine; Sulfonamides

2020

Trials

4 trial(s) available for cytarabine and glycine

ArticleYear
Two dosing regimens of tosedostat in elderly patients with relapsed or refractory acute myeloid leukaemia (OPAL): a randomised open-label phase 2 study.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aged; Aged, 80 and over; Anemia, Refractory; Cytarabine; Disease-Free Survival; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Monocytic, Acute; Male; Middle Aged; Recurrence; Remission Induction

2013
Phase II study of tosedostat with cytarabine or decitabine in newly diagnosed older patients with acute myeloid leukaemia or high-risk MDS.
    British journal of haematology, 2016, Volume: 172, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Survival Analysis; Treatment Outcome

2016
A Phase I/II Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib for Relapsed Refractory Acute Myeloid Leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 07-15, Volume: 25, Issue:14

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Boron Compounds; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Glycine; Humans; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Patient Safety; Remission Induction; Salvage Therapy; Treatment Outcome

2019
A randomised evaluation of low-dose cytosine arabinoside (ara-C) plus tosedostat versus low-dose ara-C in older patients with acute myeloid leukaemia: results of the LI-1 trial.
    British journal of haematology, 2021, Volume: 194, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Enzyme Inhibitors; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Analysis

2021

Other Studies

23 other study(ies) available for cytarabine and glycine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Treatment of the blastic phase of chronic myeloid leukaemia. A question to solve.
    Haematologica, 1972, Volume: 57, Issue:11

    Topics: Adult; Antineoplastic Agents; Child; Cytarabine; Glycine; Humans; Hydroxyurea; Leukemia, Myeloid; Purines; Remission, Spontaneous; Sulfides; Valerates; Vincristine

1972
Depression of thymidylate synthetase activity in response to cytosine arabinoside.
    Cancer research, 1972, Volume: 32, Issue:6

    Topics: Carbon Isotopes; Cell Line; Cytarabine; Cytidine; DNA; Glycine; Humans; Hypoxanthines; In Vitro Techniques; Leukemia, Lymphoid; Leukocytes; Methyltransferases; Nucleic Acids; RNA; Thymidine; Thymine Nucleotides; Time Factors; Tritium; Uracil Nucleotides; Uridine

1972
Current studies on the therapy of experimental leukemia.
    Bibliotheca haematologica, 1970, Issue:36

    Topics: Alkylating Agents; Animals; Antibodies, Viral; Cytarabine; Dactinomycin; Friend murine leukemia virus; Glycine; Leukemia, Experimental; Lymphoma, Large B-Cell, Diffuse; Mercaptopurine; Mice; Mice, Inbred BALB C; Moloney murine leukemia virus; Nitrogen Mustard Compounds; Poly I-C; Porfiromycin; Purines; Pyrans; Rauscher Virus; Remission, Spontaneous; Spleen; Vincristine; Virus Replication

1970
Relationship between erythropoietin effect and reduced DNA synthesis in marrow cell cultures.
    Biochimica et biophysica acta, 1970, Apr-15, Volume: 204, Issue:2

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Techniques; Cytarabine; Depression, Chemical; DNA; Erythropoietin; Glucosamine; Glycine; Heme; Iron; Iron Isotopes; Metabolism; Rats; Sheep; Stimulation, Chemical; Thymidine; Time Factors; Tritium

1970
Inhibition of thymidine phosphorylation and DNA and histone synthesis in Ehrlich ascites carcinoma.
    Cancer research, 1970, Volume: 30, Issue:11

    Topics: Aldehydes; Animals; Arginine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Thin Layer; Cycloheximide; Cytarabine; Cytoplasm; DNA; Glycine; Histones; Hydroxyurea; In Vitro Techniques; Lysine; Mice; Mitomycins; Nucleotides; Orotic Acid; Puromycin; Thiosemicarbazones; Thymidine; Tritium

1970
Potentiation of teratogenesis.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:3 Pt 1

    Topics: Animals; Antibiotics, Antineoplastic; Cytarabine; DNA; Drug Synergism; Embryo, Mammalian; Female; Floxuridine; Gestational Age; Glycine; Hydroxyurea; Pregnancy; Purines; Rats; Rats, Inbred Strains; Teratogens

1984
Evidence for the conversion of adenosine to 2'-deoxycoformycin by Streptomyces antibioticus.
    Biochemistry, 1984, Feb-28, Volume: 23, Issue:5

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Carbon Radioisotopes; Chromatography, Thin Layer; Coformycin; Cytarabine; Glycine; Pentostatin; Ribonucleosides; Streptomyces

1984
Correlations between necrotic patterns and limb skeletal defects induced by antimitotic drugs in the mouse.
    Progress in clinical and biological research, 1983, Volume: 110 Pt A

    Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Cell Survival; Cytarabine; Cytidine Monophosphate; Ectoderm; Extremities; Female; Glycine; Hyperplasia; Limb Deformities, Congenital; Mesoderm; Mice; Mitosis; Necrosis; Pregnancy; Time Factors

1983
Effects of methotrexate on ribonucleotide pools in growing and in growth-arrested tumor cells and antagonism by RNA synthesis inhibitors.
    The Journal of biological chemistry, 1982, Apr-25, Volume: 257, Issue:8

    Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cycloheximide; Cytarabine; Dactinomycin; Doxorubicin; Glycine; Kinetics; Methotrexate; Mice; Ribonucleotides; Transcription, Genetic

1982
Inhibition of apoptosis by the African swine fever virus Bcl-2 homologue: role of the BH1 domain.
    Virology, 1997, Feb-17, Volume: 228, Issue:2

    Topics: African Swine Fever Virus; Alanine; Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Cycloheximide; Cytarabine; Dactinomycin; Glycine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Proto-Oncogene Proteins c-bcl-2; Rabbits; Tumor Cells, Cultured; Viral Proteins

1997
Potentiation of glutamatergic agonist-induced inositol phosphate formation by basic fibroblast growth factor is related to developmental features in hippocampal cultures: neuronal survival and glial cell proliferation.
    The European journal of neuroscience, 1999, Volume: 11, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Benzoates; Cell Division; Cell Survival; Cells, Cultured; Cellular Senescence; Cycloleucine; Cytarabine; Epidermal Growth Factor; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Fibroblast Growth Factor 2; Glutamic Acid; Glycine; Hippocampus; Inositol Phosphates; Neuroglia; Neurons; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Type C Phospholipases

1999
Sivelestat relieves respiratory distress refractory to dexamethasone in all-trans retinoic acid syndrome: a report of two cases.
    European journal of haematology, 2006, Volume: 77, Issue:5

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytoprotection; Dexamethasone; Female; Glycine; Humans; Intracranial Hemorrhages; Leukemia, Promyelocytic, Acute; Male; Prospective Studies; Radiography; Randomized Controlled Trials as Topic; Remission Induction; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Tretinoin

2006
Identification of a novel point mutation in ENT1 that confers resistance to Ara-C in human T cell leukemia CCRF-CEM cells.
    FEBS letters, 2009, Jan-22, Volume: 583, Issue:2

    Topics: Amino Acid Sequence; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Membrane; Cytarabine; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Glycine; Humans; Leukemia, T-Cell; Molecular Sequence Data; Point Mutation; Protein Structure, Tertiary; RNA, Messenger; Thioinosine

2009
Glycine transporter blockade ameliorates motor ataxia in a mouse model of spinocerebellar atrophy.
    Journal of pharmacological sciences, 2009, Volume: 109, Issue:3

    Topics: Animals; Binding Sites; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Glycine; Glycine Plasma Membrane Transport Proteins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinocerebellar Ataxias

2009
Aminopeptidase inhibition by the novel agent CHR-2797 (tosedostat) for the therapy of acute myeloid leukemia.
    Leukemia research, 2011, Volume: 35, Issue:5

    Topics: Adult; Aminopeptidases; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Culture Techniques; Cytarabine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Tumor Cells, Cultured; Young Adult

2011
DAPK1-ERK signal mediates oxygen glucose deprivation reperfusion induced apoptosis in mouse N2a cells.
    Journal of the neurological sciences, 2018, 04-15, Volume: 387

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cerebral Cortex; Cytarabine; Death-Associated Protein Kinases; Disease Models, Animal; Excitatory Amino Acid Agonists; Glucose; Glycine; Hypoxia; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroblastoma; Neurons; Protein Biosynthesis; RNA, Small Interfering

2018
How I treat acute myeloid leukemia in the era of new drugs.
    Blood, 2020, 01-09, Volume: 135, Issue:2

    Topics: Adult; Aged; Aminopyridines; Aniline Compounds; Antineoplastic Agents; Biomarkers, Tumor; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Glycine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Mutation; Prognosis; Pyrazines; Pyridines; Sialic Acid Binding Ig-like Lectin 3; Staurosporine; Sulfonamides; Triazines

2020
Acute leukemias in 2020: state of the art.
    Minerva medica, 2020, Volume: 111, Issue:5

    Topics: Acute Disease; Aminopyridines; Antineoplastic Agents; Antineoplastic Agents, Immunological; Congresses as Topic; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Gemtuzumab; Glycine; Humans; Leukemia; Pyridines; Recombinant Fusion Proteins; Staurosporine; Triazines

2020
Gene expression profile predicts response to the combination of tosedostat and low-dose cytarabine in elderly AML.
    Blood advances, 2020, 10-27, Volume: 4, Issue:20

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Microarray Analysis; Transcriptome

2020
What to use to treat AML: the role of emerging therapies.
    Hematology. American Society of Hematology. Education Program, 2021, 12-10, Volume: 2021, Issue:1

    Topics: Aged; Aminopyridines; Aniline Compounds; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Approval; Drug Discovery; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Pyrazines; Pyridines; Triazines

2021