cytarabine and adenine

cytarabine has been researched along with adenine in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (51.02)	18.7374
1990's	5 (10.20)	18.2507
2000's	5 (10.20)	29.6817
2010's	11 (22.45)	24.3611
2020's	3 (6.12)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Bloch, A	1
Marks, MI	1
Brunell, P	1
Cohen, SS	2
Bianchi, V; Pontis, E; Reichard, P	1
Chisaka, O; Matsubara, K; Nagahata, T; Tsurimoto, T; Ueda, K	1
Baraĭ, VN; ERoshevskaia, LA; Kvasiuk, EI; Mikhaĭlopulo, IA; Zinchenko, AI	1
Ablashi, DV; Adamson, RH; Cicmanec, JL; Dalgard, DW	1
Connor, JD; Fishaut, JM; Lampert, PW	1
Burroughs, MA; Derge, JG; Hampar, B; Martos, LM; Tagamets, MA	1
Chang, TW; Weinstein, L	1
Luby, JP	1
Chow, AW; Fiala, M; Guze, LB; Miyasaki, K	1
Johnson, MT; Jones, SR; Luby, JP	1
Hill, DL; Wingo, R	1
Hunt, DE; Narkates, AJ	1
Ablashi, DV; Adamson, RH; Armstrong, GR; Ellmore, NW	1
Allen, LB; Sidwell, RW	1
Atkinson, MR; Burgoyne, LA; Waqar, MA	1
Hyndiuk, RA	1
Granoff, A; Kucera, LS	1
Burchenal, JH; Butterbaugh, J; Dollinger, M; Giner-Sorolla, A; Stoll, D	1
de Clercq, E	1
Baker, DC; Hanvey, JC; Hardman, JK; Suhadolnik, RJ	1
Hacker, B; Medon, PJ	1
Inui, N; Sato, S; Takizawa, H	1
Azuma, A; Hanaoka, K; Kobayashi, T; Matsuda, A; Minakawa, N; Nakajima, Y; Nishizono, N; Sasaki, T; Suzuki, M; Tanaka, M	1
Holý, A; Merta, A; Stĕtina, R; Votruba, I	1
Andrei, G; De Clercq, E; Snoeck, R	1
Borutaite, V; Tolkovsky, AM; Xue, L	1
Boyer, SH; Colby, TJ; Erion, MD; Gomez-Galeno, J; Lemus, RH; Matelich, MC; Reddy, KR; Schanzer, J; Ugarkar, BG; Van Poelje, PD	1
Bullough, DA; Colby, TJ; Erion, MD; Fujitaki, JM; Linemeyer, DL; Mackenna, DA; Montag, AC; van Poelje, PD	1
Tallman, M	1
Allen, SL; Bennett, JM; Budman, DR; Capizzi, RL; Kolitz, JE; Lundberg, AS	1
Feldman, EJ	1
Barbosa, CM; Bincoletto, C; Jurkiewicz, A; Palmeira dos Santos, C; Pereira, GJ; Smaili, SS	1
Allen, SL; Damon, L; Egyed, M; Erba, HP; Horst, HA; Jang, JH; Lundberg, AS; Masszi, T; Mazzola, E; Neuberg, D; Pigneux, A; Powell, B; Rizzieri, D; Sekeres, MA; Selleslag, D; Solomon, SR; Stone, RM; Stuart, RK; Tallman, MS; Venugopal, P; Warzocha, K; Wetzler, M	1
Gronda, M; Hurren, R; Minden, MD; Rotin, LE; Schimmer, AD; Slassi, M; Wang, X	1
Cheah, CY; Seymour, JF; Wang, ML	1
Ajami, M; Anjam-Najmedini, A; Atashi, A; Houshmand, M; Kazemi, A; Ojaghi, M; Sadri, M; Tavakoli, R; Yazdi, N; Zarif, MN	1
Beadle, JR; He, R; Hostetler, KY; Khoury, H; Minden, MD; Schimmer, A	1
Cortes, JE; Graef, T; Jonas, BA; Luan, Y; Stein, AS	1
Bonaldi, L; Branca, A; Gurrieri, C; Manni, S; Martines, A; Piazza, F; Pizzi, M; Riva, M; Scapinello, G; Semenzato, G; Trentin, L; Visentin, A	1
Arasaretnam, A; Bishton, M; Bolam, S; Creasey, T; Crosbie, N; Dawi, S; Dutton, D; Eyre, TA; Follows, G; Goradia, H; Harrison, S; Johnston, R; Kirkwood, AA; Lambert, J; Lewis, D; McCulloch, R; McKay, P; McMillan, A; Miles, O; Osborne, W; Patmore, R; Phillips, N; Robinson, A; Rule, S; Wilson, MR	1
Badillo, M; Fayad, L; Feng, L; Flowers, CR; Fowler, N; Hagemeister, FB; Hill, HA; Iyer, SP; Jain, P; Jorgensen, J; Kanagal-Shamanna, R; Lee, HJ; Li, S; Lin, P; Medeiros, LJ; Nair, R; Nastoupil, L; Navsaria, L; Nogueras Gonzalez, GM; Ok, CY; Patel, KP; Samaniego, F; Santos, D; Steiner, R; Tang, G; Thirumurthi, S; Vega, F; Wagner-Bartak, N; Wang, L; Wang, ML; Wang, SA; Westin, JR; Xu, G; Xuelin, H; Yao, Y; Yin, CC; Zhao, S	1

Reviews

6 review(s) available for cytarabine and adenine

Article	Year
The structure of nucleosides in relation to their biological and and biochemical activity: a summary. Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255 Topics: 3-Deazauridine; Adenine; Adenosine; Anti-Bacterial Agents; Azacitidine; Cytarabine; Idoxuridine; Isopentenyladenosine; Nucleosides; Pseudouridine; Puromycin; Structure-Activity Relationship; Tubercidin; Uridine	1975
The mechanisms of lethal action of arabinosyl cytosine (araC) and arabinosyl adenine (araA). Cancer, 1977, Volume: 40, Issue:1 Suppl Topics: Adenine; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Azepines; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; Cytidine Deaminase; Cytosine Nucleotides; Deoxyribonucleosides; DNA; Humans; Inosine Nucleotides; Leukemia; Tetrahydrouridine; Vidarabine; Virus Diseases	1977
Inhibitors of adenosine deaminase and the development of antiviral agents. Annals of the New York Academy of Sciences, 1985, Volume: 451 Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Antiviral Agents; Cytarabine; Deoxyadenosines; Drug Synergism; Herpes Simplex; Humans; Interferons; Mice; Nucleoside Deaminases; S-Adenosylhomocysteine; S-Adenosylmethionine	1985
Antiviral chemotherapy. Annual review of medicine, 1974, Volume: 25 Topics: Adenine; Amantadine; Antiviral Agents; Arabinose; Cytarabine; Cytomegalovirus Infections; Herpesviridae Infections; Humans; Idoxuridine; Indoles; Infant, Newborn; Infant, Newborn, Diseases; Influenza, Human; Interferons; Nucleosides; Poly I-C; Species Specificity; Thiosemicarbazones; Virus Replication	1974
Nucleoside analogues as antiviral agents. Acta microbiologica Academiae Scientiarum Hungaricae, 1981, Volume: 28, Issue:3 Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; Guanine; Herpesviridae Infections; Humans; Idoxuridine; Nucleosides; Ribavirin; Thymidine; Virus Diseases; Viruses	1981
Mantle Cell Lymphoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Apr-10, Volume: 34, Issue:11 Topics: Adenine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Bortezomib; Cytarabine; Drug Administration Schedule; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Lenalidomide; Lymphoma, Mantle-Cell; Maintenance Chemotherapy; Molecular Targeted Therapy; Neoplasm Staging; Piperidines; Prognosis; Pyrazoles; Pyrimidines; Risk Factors; Rituximab; Thalidomide; Transplantation, Autologous	2016

Trials

5 trial(s) available for cytarabine and adenine

Article	Year
Antiviral drugs for the neonate--the risk-benefit ledger. The Journal of pediatrics, 1975, Volume: 86, Issue:2 Topics: Adenine; Animals; Antiviral Agents; Arabinose; Brain; Brain Diseases; Clinical Trials as Topic; Cytarabine; Cytomegalovirus Infections; DNA, Viral; Female; Herpes Simplex; Humans; Idoxuridine; Infant, Newborn; Infant, Newborn, Diseases; Mice; Nucleosides; Pregnancy; Pregnancy Complications, Infectious	1975
Phase I trials of amonafide as monotherapy and in combination with cytarabine in patients with poor-risk acute myeloid leukemia. Leukemia research, 2010, Volume: 34, Issue:4 Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Remission Induction; Risk Factors; Treatment Outcome; Young Adult	2010
Phase III open-label randomized study of cytarabine in combination with amonafide L-malate or daunorubicin as induction therapy for patients with secondary acute myeloid leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Apr-10, Volume: 33, Issue:11 Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Induction Chemotherapy; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Prospective Studies; Remission Induction; Time Factors; Treatment Outcome; Young Adult	2015
Clinical Experience With Ibrutinib Alone or in Combination With Either Cytarabine or Azacitidine in Patients With Acute Myeloid Leukemia. Clinical lymphoma, myeloma & leukemia, 2019, Volume: 19, Issue:8 Topics: Adenine; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cohort Studies; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Non-Randomized Controlled Trials as Topic; Piperidines; Prognosis; Pyrazoles; Pyrimidines; Remission Induction; Survival Rate	2019
Ibrutinib-rituximab followed by R-HCVAD as frontline treatment for young patients (≤65 years) with mantle cell lymphoma (WINDOW-1): a single-arm, phase 2 trial. The Lancet. Oncology, 2022, Volume: 23, Issue:3 Topics: Adenine; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Lymphoma, Mantle-Cell; Lymphopenia; Methotrexate; Middle Aged; Piperidines; Rituximab; Thrombocytopenia; Treatment Outcome; Vincristine	2022

Other Studies

38 other study(ies) available for cytarabine and adenine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Evaluation of four antiviral agents in the treatment of herpes simplex encephalitis in a rat model. The Journal of infectious diseases, 1975, Volume: 131, Issue:1 Topics: Acetanilides; Adenine; Animals; Antiviral Agents; Arabinose; Brain; Cell Line; Culture Techniques; Cytarabine; Dimethylamines; Disease Models, Animal; Drug Evaluation; Encephalitis; Herpes Simplex; Idoxuridine; Inosine; Kidney; Lung; Nucleosides; Rabbits; Rats; Simplexvirus	1975
Dynamics of the dATP pool in cultured mammalian cells. Experimental cell research, 1992, Volume: 199, Issue:1 Topics: 3T3 Cells; Adenine; Animals; Aphidicolin; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Hypoxanthine; Hypoxanthines; Kinetics; Mice; Pentostatin; Substrate Cycling; Thymine Nucleotides	1992
An in vitro system for screening anti-hepatitis B virus drugs. Virology, 1989, Volume: 169, Issue:1 Topics: Acyclovir; Adenine; Antiviral Agents; Blotting, Southern; Carcinoma, Hepatocellular; Cytarabine; Dideoxyadenosine; Dideoxynucleosides; DNA Replication; DNA, Viral; Hepatitis B virus; Humans; Interferons; Liver Neoplasms; Tumor Cells, Cultured; Vidarabine; Virus Replication; Zalcitabine; Zidovudine	1989
[Preparative synthesis of the antiviral nucleoside 9-beta-D-arabinofuranosyladenine by using bacterial cells]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1986, Volume: 31, Issue:3 Topics: Adenine; Antiviral Agents; Buffers; Culture Media; Cytarabine; Dose-Response Relationship, Drug; Escherichia coli; Hydrogen-Ion Concentration; Temperature; Vidarabine	1986
Chemotherapy of Herpesvirus saimiri induced lymphoma-leukemia in the owl monkey. Journal of medical primatology, 1974, Volume: 3, Issue:1 Topics: Adenine; Animals; Arabinose; Cyclophosphamide; Cytarabine; Disease Models, Animal; Haplorhini; Herpesviridae; Hydrocortisone; Interferons; Leukemia, Lymphoid; Leukocyte Count; Lymphoma; Monkey Diseases; Oncogenic Viruses; Vincristine; Virus Replication	1974
Comparative effects of arabinosyl nucleosides upon the postnatal growth and development of the rat. Pediatric research, 1974, Volume: 8, Issue:10 Topics: Adenine; Animals; Antimetabolites; Antiviral Agents; Arabinose; Behavior, Animal; Cerebellum; Cytarabine; Floxuridine; Growth; Hypoxanthines; Injections, Intraperitoneal; Locomotion; Motor Activity; Nucleosides; Rats; Time Factors	1974
Sequence of spontaneous Epstein-Barr virus activation and selective DNA synthesis in activated cells in the presence of hydroxyurea. Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:9 Topics: Adenine; Antigens, Viral; Autoradiography; Bromodeoxyuridine; Carbon Isotopes; Carcinoma; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Cytarabine; DNA, Viral; Fluorescent Antibody Technique; Herpesviridae; Herpesvirus 4, Human; Humans; Hydroxyurea; Nasopharyngeal Neoplasms; Thymidine; Thymidine Kinase; Tritium; Virus Replication	1972
The chemotherapy of viral infections. The New England journal of medicine, 1973, Oct-04, Volume: 289, Issue:14 Topics: Acridines; Adenine; Amantadine; Amino Alcohols; Antiviral Agents; Arabinose; Benzoates; Coloring Agents; Cytarabine; Dimethylamines; Drug Combinations; Herpes Simplex; Humans; Idoxuridine; Indoles; Inosine; Interferons; Light; Nucleosides; Phenazines; Rifampin; Simplexvirus; Thiosemicarbazones; Virus Diseases; Virus Replication	1973
Varicella-zoster virus. The Journal of investigative dermatology, 1973, Volume: 61, Issue:4 Topics: Adenine; Antibodies, Viral; Antibody Formation; Antigens, Viral; Arabinose; Chickenpox; Cytarabine; Cytopathogenic Effect, Viral; Herpes Zoster; Herpesviridae Infections; Herpesvirus 3, Human; Humans; Hypersensitivity, Delayed; Nucleosides; Virus Cultivation; Virus Replication	1973
Susceptibility of herpesviruses to three nucleoside analogues and their combinations and enhancement of the antiviral effect of acid pH. The Journal of infectious diseases, 1974, Volume: 129, Issue:1 Topics: Adenine; Antiviral Agents; Cell Migration Inhibition; Cells, Cultured; Cytarabine; Cytomegalovirus; Cytopathogenic Effect, Viral; Deoxyuridine; Herpesviridae Infections; Herpesvirus 3, Human; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Nucleosides; Simplexvirus	1974
Nonspecific inhibition of precursor uptake by alkyl-substituted purines and prednisolone. Chemico-biological interactions, 1974, Volume: 9, Issue:4 Topics: Acetates; Adenine; Adenocarcinoma; Animals; Carbon Radioisotopes; Cell Division; Cell Line; Choline; Cytarabine; DNA, Neoplasm; Ethanolamines; Glucosamine; Glycoproteins; Isotope Labeling; Leukemia L1210; Lipids; Mice; Neoplasm Proteins; Prednisolone; Thymidine; Time Factors; Tritium	1974
The gross and biochemical effects of 1- -D-arabinofuranosyl cytosine on an actinobolin-resistant strain of Streptococcus faecalis. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 142, Issue:3 Topics: Adenine; Anti-Bacterial Agents; Bacterial Proteins; Carbon Isotopes; Cytarabine; Cytosine Nucleotides; DNA, Bacterial; Drug Resistance, Microbial; Enterococcus faecalis; Formates; RNA, Bacterial; Thymidine; Tritium; Uridine	1973
Effect of cytosine arabinoside, adenine arabinoside, tilorone, and rifamycin SV on multiplication of Herpesvirus saimiri in vitro. Antimicrobial agents and chemotherapy, 1972, Volume: 1, Issue:1 Topics: Adenine; Arabinose; Cytarabine; Diethylamines; Fluorenes; Herpesviridae; Nucleosides; Rifamycins; Virus Replication	1972
Target-organ treatment of neurotropic virus diseases: efficacy as a chemotherapy tool and comparison of activity of adenine arabinoside, cytosine arabinoside, idoxuridine, and trifluorothymidine. Antimicrobial agents and chemotherapy, 1972, Volume: 2, Issue:3 Topics: Adenine; Animals; Antiviral Agents; Arabinose; Brain; Cytarabine; Fluorine; Herpes Simplex; Idoxuridine; Male; Mice; Nucleosides; Organ Specificity; Thymidine; Vaccinia	1972
Deoxyribonucleic acid synthesis in mammalian nuclei. Incorporation of deoxyribonucleotides and chain-terminating nucleotide analogues. The Biochemical journal, 1971, Volume: 121, Issue:5 Topics: Adenine; Animals; Arabinose; Calcium; Cell Fractionation; Cell Nucleus; Cytarabine; Deoxyribonucleotides; DNA; DNA Nucleotidyltransferases; Liver; Liver Regeneration; Magnesium; Male; Nucleotides; Phosphorus Isotopes; Rats; Templates, Genetic; Thymus Gland	1971
Medical and surgical management of viral keratitis. Wisconsin medical journal, 1971, Volume: 70, Issue:5 Topics: Adenine; Arabinose; Cytarabine; Humans; Keratitis, Dendritic; Nucleosides; Rifampin; Uracil	1971
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells. Virology, 1968, Volume: 34, Issue:2 Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA, Viral; Herpesviridae; Hydroxyurea; Idoxuridine; Inclusion Bodies, Viral; Kidney Neoplasms; Leucine; Neoplasms, Experimental; Oncogenic Viruses; Protein Biosynthesis; RNA; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins; Virus Replication	1968
Studies of 6-N-hydroxylamino-9-beta-D-ribofuranosylpurine in mouse leukemia. Biochemical pharmacology, 1967, Volume: 16, Issue:3 Topics: Adenine; Animals; Body Weight; Cytarabine; Drug Antagonism; Drug Synergism; Fluorouracil; Guanine; Leukemia; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Nucleosides; Phosphotransferases; Purines; Vincristine	1967
Evidence for the conversion of adenosine to 2'-deoxycoformycin by Streptomyces antibioticus. Biochemistry, 1984, Feb-28, Volume: 23, Issue:5 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Carbon Radioisotopes; Chromatography, Thin Layer; Coformycin; Cytarabine; Glycine; Pentostatin; Ribonucleosides; Streptomyces	1984
Cytotoxic effects of Eleutherococcus senticosus aqueous extracts in combination with N6-(delta 2-isopentenyl)-adenosine and 1-beta-D-arabinofuranosylcytosine against L1210 leukemia cells. Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:2 Topics: Adenine; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; In Vitro Techniques; Isopentenyladenosine; Leukemia L1210; Mice; Plant Extracts	1984
Mouse strain differences in induction of micronuclei by base analogues and nucleosides. Mutation research, 1993, Volume: 301, Issue:1 Topics: Adenine; Animals; Bromodeoxyuridine; Bromouracil; Cytarabine; Erythrocytes; Female; Floxuridine; Guanosine; Mercaptopurine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Micronucleus Tests; Mitogens; Nucleosides; Purines; Pyrimidines; Species Specificity; Thymidine; Uridine	1993
Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum. Journal of medicinal chemistry, 1993, Dec-24, Volume: 36, Issue:26 Topics: Adenine; Animals; Antineoplastic Agents; Cytarabine; Female; Fluorouracil; Humans; Leukemia L1210; Lymphoma, Large B-Cell, Diffuse; Mice; Molecular Structure; Neoplasm Transplantation; Structure-Activity Relationship; Thymine; Tumor Cells, Cultured; Uracil	1993
The effect of purine phosphonomethoxyalkyl derivatives on DNA synthesis in CHO Chinese hamster cells. Neoplasma, 1993, Volume: 40, Issue:6 Topics: Adenine; Animals; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Cytarabine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Guanine; Organophosphonates; Organophosphorus Compounds; Zidovudine	1993
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:7 Topics: Acyclovir; Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Fibroblasts; Foscarnet; Humans; Lung; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid	1996
Inhibition of mitochondrial permeability transition and release of cytochrome c by anti-apoptotic nucleoside analogues. Biochemical pharmacology, 2002, Aug-01, Volume: 64, Issue:3 Topics: Adenine; Animals; Arabinofuranosylcytosine Triphosphate; Cytarabine; Cytochrome c Group; Drug Interactions; Enzyme Inhibitors; Ion Channels; Kinetin; Male; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nucleic Acid Synthesis Inhibitors; Purines; Rats; Rats, Wistar	2002
Design, synthesis, and characterization of a series of cytochrome P(450) 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver. Journal of the American Chemical Society, 2004, Apr-28, Volume: 126, Issue:16 Topics: Adenine; Animals; Catalysis; Cytarabine; Cytochrome P-450 Enzyme System; Drug Delivery Systems; Drug Design; Hepatocytes; Humans; Liver; Male; Organophosphonates; Phosphates; Phosphotransferases; Prodrugs; Rats; Stereoisomerism; Time Factors; Vidarabine	2004
Liver-targeted drug delivery using HepDirect prodrugs. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2 Topics: Acetaminophen; Adenine; Analgesics, Non-Narcotic; Animals; Biotransformation; Bone Marrow; Cell Separation; Cytarabine; Drug Delivery Systems; Glutathione; Hepatocytes; In Vitro Techniques; Inactivation, Metabolic; Liver; Male; Mice; Organophosphonates; Organophosphorus Compounds; Prodrugs; Rats; Tissue Distribution	2005
Existing and emerging therapeutic options for the treatment of acute myeloid leukemia. Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11 Topics: Adenine; Adenine Nucleotides; Aminoglycosides; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Carbazoles; Clofarabine; Cytarabine; Dasatinib; Daunorubicin; fms-Like Tyrosine Kinase 3; Furans; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Sesquiterpenes; Staurosporine; Stem Cell Transplantation; Thiazoles; Tretinoin	2008
Does therapy-related AML have a poor prognosis, independent of the cytogenetic/molecular determinants? Best practice & research. Clinical haematology, 2011, Volume: 24, Issue:4 Topics: Adenine; Anthracyclines; Antineoplastic Agents; Biomarkers, Tumor; Cytarabine; Cytogenetics; Female; Germany; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Naphthalimides; Naphthyridines; Organophosphonates; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Thiazoles	2011
Comparative study of autophagy inhibition by 3MA and CQ on Cytarabine‑induced death of leukaemia cells. Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:6 Topics: Adenine; Antimalarials; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Blotting, Western; Caspase 3; Cell Proliferation; Chloroquine; Cytarabine; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunophenotyping; Leukemia; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Tumor Cells, Cultured; Tumor Stem Cell Assay	2014
Investigating the synergistic mechanism between ibrutinib and daunorubicin in acute myeloid leukemia cells. Leukemia & lymphoma, 2016, Volume: 57, Issue:10 Topics: Adenine; Cytarabine; Daunorubicin; Leukemia, Myeloid, Acute; Piperidines; Pyrazoles; Pyrimidines	2016
Chemotherapy of mantle cell lymphoma relapsed or refractory chronic lymphocytic leukaemia. Prescrire international, 2016, Volume: 25, Issue:170 Topics: Adenine; Antineoplastic Agents; Bendamustine Hydrochloride; Bortezomib; Chromosomes, Human, Pair 17; Cytarabine; Humans; Lenalidomide; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Mutation; Neoplasm Recurrence, Local; Piperidines; Pyrazoles; Pyrimidines; Rituximab; Sirolimus; Thalidomide; Tumor Suppressor Protein p53; Vidarabine	2016
The anticancer effects of pharmacological inhibition of autophagy in acute erythroid leukemia cells. Anti-cancer drugs, 2018, Volume: 29, Issue:10 Topics: Adenine; Antimetabolites, Antineoplastic; Autophagy; Cell Line, Tumor; Chloroquine; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cytarabine; Down-Regulation; G1 Phase; Humans; Leukemia, Erythroblastic, Acute; MicroRNAs; Resting Phase, Cell Cycle; Up-Regulation	2018
Octadecyloxyethyl Adefovir Exhibits Potent in vitro and in vivo Cytotoxic Activity and Has Synergistic Effects with Ara-C in Acute Myeloid Leukemia. Chemotherapy, 2018, Volume: 63, Issue:4 Topics: Adenine; Animals; Apoptosis; Caspases; Cell Cycle Checkpoints; Cytarabine; DNA Damage; Drug Compounding; Drug Resistance, Neoplasm; Drug Synergism; Female; Histones; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Organophosphonates; Poly(ADP-ribose) Polymerases; Transplantation, Heterologous; Tumor Cells, Cultured	2018
A case of "double hit" mantle cell lymphoma carrying CCND1 and MYC translocations relapsed/refractory to rituximab bendamustine cytarabine (R-BAC) and ibrutinib. Annals of hematology, 2020, Volume: 99, Issue:11 Topics: Abnormal Karyotype; Adenine; Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Biomarkers, Tumor; Bortezomib; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 8; Cyclin D1; Cytarabine; Drug Resistance, Neoplasm; Fatal Outcome; Gene Duplication; Genes, myc; Humans; Lymphoma, Mantle-Cell; Male; Oncogene Proteins, Fusion; Piperidines; Pyrazoles; Pyrimidines; Recurrence; Rituximab; Translocation, Genetic	2020
Ibrutinib for mantle cell lymphoma at first relapse: a United Kingdom real-world analysis of outcomes in 211 patients. British journal of haematology, 2021, Volume: 193, Issue:2 Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Cytarabine; Disease Progression; Female; Humans; Lymphoma, Mantle-Cell; Male; Middle Aged; Outcome Assessment, Health Care; Piperidines; Progression-Free Survival; Protein Kinase Inhibitors; Recurrence; Retrospective Studies; Rituximab; State Medicine; United Kingdom; Withholding Treatment	2021