cyc 202 has been researched along with adenine in 25 studies
| Studies (cyc 202) | Trials (cyc 202) | Recent Studies (post-2010) (cyc 202) | Studies (adenine) | Trials (adenine) | Recent Studies (post-2010) (adenine) |
|---|---|---|---|---|---|
| 979 | 7 | 393 | 21,903 | 1,153 | 7,682 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 14 (56.00) | 29.6817 |
| 2010's | 8 (32.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hanus, J; Havlícek, L; Leclerc, S; Meijer, L; Shaw, G; Strnad, M; Veselý, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bergounioux, C; Glab, N; Perennes, C; Planchais, S; Tregear, J; Tréhin, C | 1 |
| Détivaud, L; Doerig, C; Gray, N; Meijer, L | 1 |
| Ducrot, P; Endicott, J; Grierson, DS; Legraverend, M; Leost, M; Ludwig, O; Meijer, L; Noble, M; Tunnah, P | 1 |
| Bertout, M; Bodart, JF; Browaeys, E; Flament, S; Rousseau, A; Vilain, JP | 1 |
| Doerig, C; Gray, N; Harmse, L; Havlik, I; Leclerc, S; Meijer, L; Schultz, P; van Zyl, R | 1 |
| Faerge, I; Hyttel, P; Mayes, M; Sirard, MA | 1 |
| Choi, YH; Hinrichs, K; Love, CC; Reinoehl, C; Varner, DD; Wiggins, CN | 1 |
| Bantly, A; Gray, NS; Knockaert, M; Malim, MH; Meijer, L; Schaffer, PA; Schang, LM; Shaheen, F | 1 |
| Koca, J; Kríz, Z; Otyepka, M | 1 |
| Camera, JC; Canduri, F; Filgueira de Azevedo, W; Freitas da Silveira, NJ; Gaspar, RT | 1 |
| Blagoeva, E; Gaudinová, A; Malbeck, J; Vanek, T; Vanková, R | 1 |
| Le Beux, G; Richard, FJ; Sirard, MA | 1 |
| Bártová, I; Koca, J; Kríz, Z; Otyepka, M | 1 |
| Choi, YH; Chung, YG; Hinrichs, K; Love, CC; Varner, DD | 1 |
| Choi, YH; Hartman, DL; Hinrichs, K; Varner, DD | 1 |
| Wani, NA | 1 |
| Brito, AB; Domingues, SF; Leão, DL; Lima, JS; Miranda, MS; Ohashi, OM; Sampaio, RV; Santos, RR | 1 |
| Aremu, AO; Bairu, MW; Doležal, K; Finnie, JF; Novák, O; Plačková, L; Strnad, M; Van Staden, J; Zatloukal, M | 1 |
| Bettayeb, K; Bustos, V; Flajolet, M; Galons, H; Greengard, P; Luo, W; Meijer, L; Oumata, N; Zhang, Y | 1 |
| Bukanov, NO; Galons, H; Ibraghimov-Beskrovnaya, O; Ledbetter, SR; Meijer, L; Moreno, SE; Natoli, TA; Oumata, N; Rogers, KA; Smith, LA | 1 |
| Blanco, ID; da Cruz Landim-Alvarenga, F; de Lima Neto, JF; Devito, LG; Fernandes, CB; Gonçalves, CG; Martins, LR; Tsuribe, PM | 1 |
| Arisan, ED; Coker-Gurkan, A; Obakan-Yerlikaya, P; Ozfiliz-Kilbas, P; Palavan-Unsal, N; Sarikaya, B; Temizci, B | 1 |
| Encheva, V; Heesom, KJ; Lach, R; Ray, S; Reddy, AB; Snijders, AP; Valekunja, UK | 1 |
1 review(s) available for cyc 202 and adenine
| Article | Year |
|---|---|
ATP-site directed inhibitors of cyclin-dependent kinases.
Topics: Adenine; Adenosine Triphosphate; Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Cell Cycle; Cyclin-Dependent Kinases; Drug Design; Enzyme Inhibitors; Flavonoids; Humans; Isopentenyladenosine; Kinetin; Molecular Sequence Data; Piperidines; Purines; Roscovitine; Sequence Alignment; Sequence Homology, Amino Acid; Staurosporine; Suramin | 1999 |
24 other study(ies) available for cyc 202 and adenine
| Article | Year |
|---|---|
Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds.
Topics: Animals; CDC2 Protein Kinase; CDC28 Protein Kinase, S cerevisiae; Enzyme Inhibitors; Kinetin; Oocytes; Purines; Roscovitine; Starfish; Tumor Cells, Cultured | 1997 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Cell cycle regulation by plant growth regulators: involvement of auxin and cytokinin in the re-entry of Petunia protoplasts into the cell cycle.
Topics: 2,4-Dichlorophenoxyacetic Acid; Adenine; Benzyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Cell Cycle; Cytokinins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Indoleacetic Acids; Kinetin; Molecular Sequence Data; Plant Cells; Plant Growth Regulators; Plants; Protoplasts; Purines; Roscovitine | 1998 |
Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex.
Topics: Adenine; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Crystallography, X-Ray; Cyclin B; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Protein Serine-Threonine Kinases; Purines; Roscovitine; Structure-Activity Relationship | 2000 |
Differential effects of 6-DMAP, olomoucine and roscovitine on Xenopus oocytes and eggs.
Topics: Adenine; Animals; Blotting, Western; CDC2 Protein Kinase; Cyclin B; Cyclin-Dependent Kinases; Enzyme Inhibitors; Female; In Vitro Techniques; Kinetin; Meiosis; Microinjections; Mitogen-Activated Protein Kinase 1; Oocytes; Ovum; Protein Kinases; Purines; Roscovitine; Xenopus laevis | 2000 |
Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum.
Topics: Adenine; Animals; Antimalarials; Cell Cycle; Dose-Response Relationship, Drug; Isopentenyladenosine; Kinetin; Parasitic Sensitivity Tests; Phosphotransferases; Plasmodium falciparum; Purines; Roscovitine; Structure-Activity Relationship | 2001 |
Nuclear ultrastructure in bovine oocytes after inhibition of meiosis by chemical and biological inhibitors.
Topics: 4-Butyrolactone; Adenine; Animals; Antineoplastic Agents; Cattle; Cell Nucleolus; Cell Nucleus; Cells, Cultured; Cycloheximide; Enzyme Inhibitors; Female; Meiosis; Microscopy, Electron; Nuclear Envelope; Oocytes; Protein Synthesis Inhibitors; Purines; Roscovitine | 2001 |
Suppression of meiosis by inhibitors of m-phase proteins in horse oocytes with low meiotic competence.
Topics: 4-Butyrolactone; Adenine; Animals; Chromatin; Dimethyl Sulfoxide; Horses; Meiosis; Oocytes; Oogenesis; Purines; Roscovitine | 2002 |
Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins.
Topics: Adenine; Animals; Antiviral Agents; Cell Cycle; Cell Line; Chlorocebus aethiops; Cyclin-Dependent Kinases; Drug Resistance, Viral; Enzyme Inhibitors; HIV-1; Humans; Purines; Roscovitine; Simplexvirus; Vero Cells; Viral Proteins; Virus Replication | 2002 |
Dynamics and binding modes of free cdk2 and its two complexes with inhibitors studied by computer simulations.
Topics: Adenine; Binding Sites; Computer Simulation; Crystallography, X-Ray; Cyclin-Dependent Kinases; Drug Design; Hydrogen Bonding; Isopentenyladenosine; Kinetics; Ligands; Models, Molecular; Molecular Structure; Protein Conformation; Purines; Roscovitine; Static Electricity | 2002 |
Molecular model of cyclin-dependent kinase 5 complexed with roscovitine.
Topics: Adenine; Adenosine Triphosphate; Amino Acid Sequence; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Purines; Roscovitine; Sequence Homology, Amino Acid; Software | 2002 |
Cyclin-dependent kinase inhibitor, roscovitine, in combination with exogenous cytokinin, N6-benzyladenine, causes increase of cis-cytokinins in immobilized tobacco cells.
Topics: Adenine; Alginates; Benzyl Compounds; Cell Survival; Cells, Cultured; Cells, Immobilized; Cyclin-Dependent Kinases; Cytokinins; Glucuronic Acid; Hexuronic Acids; Isopentenyladenosine; Kinetin; Nicotiana; Purines; Reproducibility of Results; Roscovitine; Sensitivity and Specificity | 2003 |
Effect of cycloheximide, 6-DMAP, roscovitine and butyrolactone I on resumption of meiosis in porcine oocytes.
Topics: 4-Butyrolactone; Adenine; Animals; Cells, Cultured; Cyclin-Dependent Kinases; Cycloheximide; Enzyme Inhibitors; Female; Meiosis; Oocytes; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Purines; Roscovitine; Swine | 2003 |
Analysis of CDK2 active-site hydration: a method to design new inhibitors.
Topics: Adenine; Adenosine Triphosphate; Binding Sites; CDC2-CDC28 Kinases; Computer Simulation; Crystallography, X-Ray; Cyclin-Dependent Kinase 2; Drug Design; Enzyme Inhibitors; Hydrogen Bonding; Isopentenyladenosine; Models, Molecular; Protein Structure, Secondary; Purines; Roscovitine; Solvents; Static Electricity; Thermodynamics; Water | 2004 |
Production of horse foals via direct injection of roscovitine-treated donor cells and activation by injection of sperm extract.
Topics: Adenine; Animals; Cell Extracts; Cells, Cultured; Cloning, Organism; Culture Media; Cycloheximide; Embryo Transfer; Female; Fibroblasts; Flow Cytometry; Horses; Hybrid Cells; Male; Microinjections; Nuclear Transfer Techniques; Oocytes; Purines; Roscovitine; Spermatozoa | 2006 |
Production of cloned horse foals using roscovitine-treated donor cells and activation with sperm extract and/or ionomycin.
Topics: Adenine; Animals; Blastocyst; Calcium; Cell Culture Techniques; Cleavage Stage, Ovum; Cloning, Organism; Embryo Transfer; Embryonic Development; Female; Horses; Ionomycin; Male; Microinjections; Nuclear Transfer Techniques; Oocyte Donation; Oocytes; Pregnancy; Pregnancy Outcome; Protein Kinase Inhibitors; Purines; Roscovitine; Sperm Injections, Intracytoplasmic | 2007 |
Chemical activation of in vitro matured dromedary camel (Camelus dromedarius) oocytes: optimization of protocols.
Topics: Adenine; Animals; Camelus; Cell Count; Ethanol; Female; Fertilization in Vitro; Ionomycin; Ionophores; Oocytes; Parthenogenesis; Phosphorylation; Protein Kinase Inhibitors; Purines; Random Allocation; Roscovitine | 2008 |
Embryo production by parthenogenetic activation and fertilization of in vitro matured oocytes from Cebus apella.
Topics: Adenine; Animals; Cebus; Cells, Cultured; Embryo, Mammalian; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Hormones; Luteinizing Hormone; Male; Metaphase; Oocytes; Parthenogenesis; Protein Kinase Inhibitors; Purines; Roscovitine; Spermatozoa | 2013 |
Physiological responses and endogenous cytokinin profiles of tissue-cultured 'Williams' bananas in relation to roscovitine and an inhibitor of cytokinin oxidase/dehydrogenase (INCYDE) treatments.
Topics: Adenine; Benzyl Compounds; Biomass; Cyclin-Dependent Kinases; Cytokinins; Kinetin; Musa; Oxidoreductases; Phenols; Photosynthesis; Plant Components, Aerial; Plant Growth Regulators; Plant Proteins; Purines; Roscovitine; Signal Transduction; Tissue Culture Techniques | 2012 |
Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action.
Topics: Adenine; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Blotting, Western; Brain; Celecoxib; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Fenofibrate; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Proteins; Muscle Proteins; Neurons; Organic Chemicals; Peptide Fragments; Prohibitins; Protein Binding; Purines; Pyrazoles; Repressor Proteins; Roscovitine; Sulfonamides; Voltage-Dependent Anion Channel 1 | 2012 |
CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD.
Topics: Adenine; Animals; Apoptosis; Cyclin-Dependent Kinases; Disease Models, Animal; Humans; Kidney Diseases, Cystic; Liver Diseases; Mice; Mice, Knockout; Polycystic Kidney, Autosomal Dominant; Protein Kinase C; Protein Kinase Inhibitors; Purines; Roscovitine | 2012 |
Artificial activation of bovine and equine oocytes with cycloheximide, roscovitine, strontium, or 6-dimethylaminopurine in low or high calcium concentrations.
Topics: Adenine; Animals; Calcium; Cattle; Cells, Cultured; Cycloheximide; Female; Horses; In Vitro Oocyte Maturation Techniques; Ionomycin; Oocytes; Parthenogenesis; Purines; Roscovitine; Strontium | 2014 |
Cyclin-dependent kinase inhibitors, roscovitine and purvalanol, induce apoptosis and autophagy related to unfolded protein response in HeLa cervical cancer cells.
Topics: Adenine; Autophagy; Cell Proliferation; Cell Survival; Endoplasmic Reticulum Stress; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Protein Kinase Inhibitors; Purines; Reactive Oxygen Species; Roscovitine; Time Factors; Unfolded Protein Response; Uterine Cervical Neoplasms | 2018 |
Phenotypic proteomic profiling identifies a landscape of targets for circadian clock-modulating compounds.
Topics: Adenine; Anthracenes; Cell Line, Tumor; Circadian Clocks; Circadian Rhythm; Drug Evaluation, Preclinical; Humans; Phenotype; Phosphorylation; Proteomics; Purines; Roscovitine; Signal Transduction; Transcription Factors | 2019 |