creatine and glycine
creatine has been researched along with glycine in 291 studies
Research
Studies (291)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 72 (24.74) | 18.7374 |
| 1990's | 25 (8.59) | 18.2507 |
| 2000's | 75 (25.77) | 29.6817 |
| 2010's | 87 (29.90) | 24.3611 |
| 2020's | 32 (11.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
| Walker, JB | 1 |
| Fisher, H; Sitren, HS | 1 |
| O'Connor, WJ; Summerill, RA | 1 |
| Kadono, K; Tetsutani, T; Yamaguchi, T; Yasunaga, K | 1 |
| Breyer, D; Granić, M; Milutinović, S; Rocić, B | 1 |
| Brzeski, M; Buchanan, LM; Marabani, M; McKillop, JH; Reglinski, J; Smith, WE; Sturrock, RD; Thomson, JA; Wilson, R | 1 |
| Kiyatake, I; Koide, H; Kubota, M; Takeda, M; Tomino, Y | 1 |
| Shimamura, T | 1 |
| Jägerstad, M; Skog, K | 1 |
| Bachmann, E; Weber, E | 1 |
| Gray, ED; Gross, MD; Jenny, RJ; McGuire, DM; Simon, AM; Van Pilsum, JF | 1 |
| Faccini, JM; Greaves, P; Higgins, AJ | 1 |
| Muramoto, H | 1 |
| Chalmers, RA; Hind, AJ; Iles, RA | 1 |
| Bernhardt, W | 1 |
| Blisse, A; Sethi, KK; Staib, F | 1 |
| Das, JB; Filler, RM | 1 |
| Mazumdar, KK; Pal, MK | 1 |
| Austic, RE; Nesheim, MC; Wang, SH | 1 |
| Austic, RE; Nesheim, MC | 1 |
| Belavady, B; Rao, PU | 1 |
| Alsever, RN; Georg, RH; Sussman, KE | 1 |
| Stephens, GC; Taylor, D; Van Pilsum, JF | 2 |
| Burt, D; Emery, AE | 1 |
| Fuller, HL; Keshavarz, K | 2 |
| Harvey, JC | 1 |
| Methfessel, J | 1 |
| Nakamura, T; Okami, Y; Seki, Y | 1 |
| Geppert, E; Hinzen, DH; Isselhard, W; Mäurer, W | 1 |
| Van Pilsum, JF | 1 |
| Campanacci, L; Fiaschi, E; Guarnieri, GF; Siliprandi, N | 1 |
| Halberstam, D; Kaplan, D; Wallace, SL | 1 |
| O'Dell, BL; Savage, JE | 1 |
| McHugh, RB; Van Pilsum, JF; Warhol, RM | 1 |
| Estes, FL; Wetzel, RL | 1 |
| Gross, MD; McGuire, DM; Towle, HC; Van Pilsum, JF | 1 |
| Maxwell, AR; Stoner, HB; Threlfall, CJ | 1 |
| Tsukada, K; Yanokura, M | 1 |
| Fisher, H; Lavine, ME; Minuskin, ML; Ulman, EA | 1 |
| Hamaguchi, C; Hatanaka, Y; Nakata, T; Nozima, M; Ueda, K | 1 |
| Afting, EG; Bernhardt, W; Janzen, RW; Röthig, HJ | 1 |
| Sipilä, I | 1 |
| Arjomaa, P; Simell, O; Sipilä, I | 1 |
| Burlina, AP; Hagberg, G; Mader, I; Radue, EW; Roser, W; Seelig, J | 1 |
| de Deyn, PP; Levillain, O; Marescau, B | 2 |
| Chang, C; Jang, T | 1 |
| Kajiwara, H; Kinoshita, Y; Koga, Y; Yokota, A | 1 |
| De Deyn, PP; Holvoet, J; Mahler, C; Marescau, B; Nagels, G; Possemiers, I; Saxena, V | 1 |
| Eichhorn, HM; Feuerbach, S; Fründ, R; Geissler, A; Kohler, S; Krämer, BK | 1 |
| Moonen, CT; van Zijl, PC | 1 |
| Ball, WS; Dunn, RS; Kirks, DR; Nelson, SJ; Tzika, AA; Vigneron, DB | 1 |
| Ageta, T; Kodama, H; Nakayama, K; Shuin, T; Sugahara, K; Yasuda, M; Zhang, J | 1 |
| Brand, A; Dringen, R; Hamprecht, B; Leibfritz, D; Verleysdonk, S; Willker, W | 1 |
| Gray, TJ; Moore, NP; Timbrell, JA | 1 |
| Bachert, P; De Deyn, PP; Marescau, B; Mayatepek, E; Rating, D; Schulze, A | 1 |
| Jakobs, C; Jansen, EE; Struys, EA; ten Brink, HJ; van der Knaap, MS; Verhoeven, NM | 1 |
| Andreassen, OA; Beal, MF; Bogdanov, MB; Ferrante, RJ; Kaddurah-Daouk, R; Klein, AM; Klivenyi, P; Matthews, RT; Mueller, G; Wermer, M | 1 |
| Hyder, F; Mattson, RH; Petroff, OA; Rothman, DL | 1 |
| David, SS; Haley, BE | 1 |
| Connor, HD; Enomoto, N; Mason, RP; Moss, N; Thurman, RG; Zhong, Z | 1 |
| Alanen, A; Erkintalo, M; Heinänen, K; Heinonen, OJ; Komu, M; Näntö-Salonen, K; Nikoskelainen, E; Pulkki, K; Simell, O; Sipilä, I | 1 |
| Ilas, J; Mühl, A; Stöckler-Ipsiroglu, S | 1 |
| Jakobs, C; Maaswinkel-Mooij, P; Onkenhout, W; Peeters, EA; Pouwels, PJ; Stöckler-Ipsiroglu, S; van der Knaap, MS; Verhoeven, NM | 1 |
| Antonozzi, I; Carducci, C; Leuzzi, V; Mercuri, L; Prudente, S | 1 |
| Gabis, L; Huang, W; Lenn, N; Parton, P; Roche, P; Tudorica, A | 1 |
| Kodama, H; Shuin, T; Sugahara, K; Yasuda, M; Zhang, J | 1 |
| Bloesch, SM; Bodamer, OA; Gregg, AR; O'Brien, WE; Stockler-Ipsiroglu, S | 1 |
| Al Banchaabouchi, M; De Deyn, PP; Levillain, O; Marescau, B; Possemiers, I | 1 |
| Alessandrì, MG; Bianchi, MC; Cioni, G; Fornai, F; Item, CB; Mühl, A; Stöckler-Ipsiroglu, S; Stromberger, C; Tosetti, M | 1 |
| Au, KP; Brosnan, JT; Brosnan, ME; Jacobs, RL; Stead, LM | 1 |
| Ebinger, F; Mayatepek, E; Rating, D; Schulze, A | 1 |
| Jacobs, DO; Shang, L; Wang, W; Zhao, CR | 1 |
| Antonozzi, I; Battini, R; Birarelli, M; Carducci, C; Cioni, G; Leuzzi, V | 1 |
| Battini, R; Bianchi, MC; Carducci, C; Cioni, G; Item, CB; Leuzzi, V; Stöckler-Ipsiroglu, S; Tosetti, M | 1 |
| Fehr, S; Isbrandt, D; Neu, A; Neuhoff, H; Roeper, J; Trube, G; Ullrich, K | 1 |
| Hanstock, CC; Nakashima, TT; O'Donnell, T; Rotzinger, S; Silverstone, PH; Ulrich, M | 1 |
| Bodamer, OA; Stöckler-Ipsiroglu, S; Stromberger, C | 1 |
| HARPER, HA; HIGGINS, AR; JONES, RE; KIMMEL, JR; KLINE, EF; MERRILL, RS; SMITH, TW | 1 |
| CUMINGS, JN | 1 |
| CHOEN, S; FRAZIER, RG; GORDON, HH | 1 |
| JONES, AC | 1 |
| POUTSIAKA, JW | 1 |
| DE BARBIERI, A; SCEVOLA, ME | 1 |
| COLEMAN, DL | 1 |
| DINNING, JS; FITCH, CD; HSU, C | 1 |
| FITCH, CD | 1 |
| DECONNINCK, G; VOETS, JP | 1 |
| GUTMAN, AB; YUE, TF | 1 |
| AKIYA, S; NAKAI, T; TSUJIGADO, N | 1 |
| KOCH, A; LWOFF, A; LWOFF, M | 1 |
| BECKMAN, D; BOLINE, J; VANPILSUM, JF; WARHOL, RM | 1 |
| Harris, M; Laastuen, L; Todd, WR | 1 |
| LWOFF, A; LWOFF, M | 1 |
| WALKER, JB; WANG, SH | 1 |
| GORDON, JE | 1 |
| DAVIDSON, DT; STAMBAUGH, R | 1 |
| DEHAAS, JC; PILKINGTON, LA; PITTS, RF | 1 |
| HORNER, WH | 1 |
| Anderson, R; Bull, G; Groundwater, PW; Lees, G; Lough, JW; Shattock, P; Whiteley, P | 1 |
| Heerschap, A; Isbrandt, D; Oerlemans, F; Renema, WK; Schmidt, A; Ullrich, K; van Asten, JJ; Wieringa, B | 1 |
| MARTEL, F | 1 |
| HUMMEL, JP; MELVILLE, RS | 1 |
| BORSOOK, H; BORSOOK, ME | 2 |
| GRAYBIEL, A; PATTERSON, CA | 1 |
| BENEDICT, JD; BIEN, EJ; ROCHE, M; STETTEN, D; YU, TF | 1 |
| De Deyn, PP; Derave, W; Eijnde, BO; Hespel, P; Marescau, B; Vanden Eede, E | 1 |
| Ensenauer, R; Hennig, J; Lehnert, W; Schulze, A; Schwab, KO; Stöckler-Ipsiroglu, S; Tacke, U; Thiel, T | 1 |
| Almeida, LS; Cardoso, ML; Jakobs, C; Roos, B; Salomons, GS; Valongo, C; Verhoeven, NM; Vilarinho, L | 1 |
| Arias, A; Garcia-Villoria, J; Ribes, A | 1 |
| Cheillan, D; Cognat, S; Jakobs, C; Piraud, M; Roos, B; Vianey-Saban, C | 1 |
| Heerschap, A; Isbrandt, D; Kan, HE; Renema, WK | 1 |
| Almeida, L; Cardoso, ML; Domingues, P; Jakobs, C; Salomons, G; Valongo, C; Verhoeven, N; Vilarinho, L | 1 |
| Aarsen, FK; Catsman-Berrevoets, CE; de Coo, IF; Duran, M; Huijmans, JG; Jakobs, C; Kamphoven, JH; Mancini, GM; Salomons, GS; van der Knaap, MS | 1 |
| Minabe, Y; Ogino, T; Shirayama, Y; Takahashi, S | 1 |
| Beaudet, AL; Bodamer, OA; Bottiglieri, T; O'Brien, WE; Sahoo, T; Scaglia, F; Stöckler-Ipsiroglu, S; Wagner, C | 1 |
| D'Hooge, R; De Deyn, PP; Isbrandt, D; Marescau, B; Possemiers, I; Torremans, A; Van Dam, D | 1 |
| Meiners, LC; Oudkerk, M; Rake, JP; Sijens, PE; Soorani-Lunsing, RJ; Verbruggen, KT | 1 |
| Hosoya, K; Nakashima, T; Tachikawa, M; Terasaki, T; Tomi, M; Watanabe, M | 1 |
| Bell, JD; Chung, YL; Hicks, J; Miller, FW; Passo, MH; Rennebohm, RM; Rider, LG; Scott, DL; Summers, RM; Zemel, LS | 1 |
| Diehl, A; Ende, G; Heinz, A; Hermann, D; Mann, K; Walter, S; Weber-Fahr, W; Welzel, H | 1 |
| Tong, ZY; Toshiaki, Y; Wang, YJ | 1 |
| Jakobs, C; Salomons, GS; Verhoeven, NM | 1 |
| Oudkerk, M; Sijens, PE; Soorani-Lunsing, RJ; van Spronsen, FJ; Verbruggen, KT | 1 |
| Li, CQ; Shen, J; Xu, S; Yang, J; Zhu, W | 1 |
| Bailly, X; Suzuki, T; Tanaka, K; Uda, K; Zal, F | 1 |
| Antonozzi, I; Artiola, C; Battini, R; Carducci, C; Giovanniello, T; Leuzzi, V; Santagata, S | 1 |
| Andersen, PM; Brännström, T; Eisen, A; Mackenzie, IR; Marklund, SL; Stewart, HG | 1 |
| Gavaghan McKee, CL; Nicholson, JK; Wilson, ID | 1 |
| Minami, M; Mitsumori, F; Takaya, N; Watanabe, H; Yamaguchi, M | 1 |
| Jakobs, C; Reijngoud, DJ; Sijens, PE; Soorani-Lunsing, RJ; van Spronsen, FJ; Verhoeven, NM | 1 |
| Acquaviva, C; Boisson, C; Cheillan, D; Cordier, MP; François, L; Jakobs, C; Roth, P; Salomons, GS; Vianey-Saban, C | 1 |
| Carru, C; Chessa, R; Deiana, L; Sotgia, S; Zinellu, A; Zinellu, E | 1 |
| Arias, A; Artuch, R; Briones, P; García-Villoria, J; González, B; Moreno, J; Ormazabal, A; Pàmpols, T; Ribes, A; Vilaseca, MA | 1 |
| Adami, A; Appleton, R; Araújo, HC; Duran, M; Ensenauer, R; Fernandez-Alvarez, E; Garcia, P; Grolik, C; Item, CB; Jakobs, C; Leuzzi, V; Marquardt, I; Mercimek-Mahmutoglu, S; Mühl, A; Saelke-Kellermann, RA; Salomons, GS; Schulze, A; Stoeckler-Ipsiroglu, S; Surtees, R; van der Knaap, MS; Vasconcelos, R; Verhoeven, NM; Vilarinho, L; Wilichowski, E | 1 |
| Abrar, AA; Gupta, RK; Krishnani, N; Kumar, R; Mishra, AM; Reddy S, J; Syal, R; Tyagi, I | 1 |
| Jakobs, C; Lunsing, RJ; Salomons, GS; Schulze, A; Sijens, PE; van Spronsen, FJ; Verbruggen, KT | 1 |
| Caria, MA; Carru, C; Deiana, L; Sotgia, S; Tadolini, B; Zinellu, A | 1 |
| Matsui, O; Suzuki, M; Uchiyama, N; Ueda, F | 1 |
| Arias, A; Artuch, R; Briones, P; Campistol, J; Corbella, M; Fons, C; García-Villoria, J; Ormazabal, A; Pàmpols, T; Pineda, M; Poo, P; Ribes, A; Salomons, GS; Sempere, A; Vilaseca, MA | 1 |
| Brosnan, JT; Brosnan, ME; Edison, EE; Meyer, C | 1 |
| Barth, EJ; Clarke, CN; Edmiston, PL; Fraga, D; Hale, RN; Jourden, MJ; Palmer, AK; Prada, RC; Snider, MJ | 1 |
| De Deyn, PP; De Vriese, A; Delanghe, JR; Marescau, B; Schepers, E; Taes, YE; Vanholder, R | 1 |
| SELDIN, DW; SIMS, EA | 1 |
| FLOOD, RG; PINELLI, RW | 2 |
| SIMS, EA | 1 |
| Alessandrì, MG; Battini, R; Casarano, M; Cioni, G; Leuzzi, V | 1 |
| González, RG; Halpern, EF; Lee, V; Lentz, MR; Ratai, EM; Westmoreland, SV | 1 |
| Aguirre, M; Aldámiz-Echevarría, L; Andrade, F; Ariceta, G; Elorz, J; Martin, S; Prieto, JA; Rodríguez-Soriano, J; Sanjurjo, P | 1 |
| Braissant, O; Henry, H | 1 |
| Struys, E; Wood, T; Young, S | 1 |
| Anselm, IA; Coulter, DL; Darras, BT | 1 |
| Merinero, B; Puig, JG; Torres, RJ; Verdú, A | 1 |
| Salomons, GS; Schutz, PW; Stockler, S | 1 |
| Battini, R; Schulze, A | 1 |
| Calvin, J; Carling, RS; Hogg, SL; Wood, TC | 1 |
| LEVEDAHL, BH; SAMUELS, LT | 1 |
| Aldámiz-Echevarría, L; Andrade, F; Elorz, J; Martín, S; Prieto, JA; Sanjurjo, P | 1 |
| Brosnan, JT; Brosnan, ME; da Silva, RP; Nissim, I | 1 |
| Bodamer, OA; Hung, C; Iqbal, F; Item, BC; Mühl, A; Prayer, D; Ratschmann, R | 1 |
| Bilos, A; Brussel, W; Buoni, S; de Vries, M; Engelke, UF; Hayek, J; Kluijtmans, LA; Kremer, B; Morava, E; Salomons, GS; Tassini, M; Valensin, G; Veendrick-Meekes, MJ; Vivi, A; Wevers, RA; Zannolli, R | 1 |
| Barger, AV; Campeau, NG; Port, JD; Renaud, DL | 1 |
| Bertolo, RF; Brosnan, JT; Brosnan, ME; Brunton, JA; Trottier, NL; Warford-Woolgar, L; Wijekoon, EP | 1 |
| Barros, TL; Covell, J; Evins, AE; Fava, M; Kaufman, MJ; Medeiros, CL; Ongur, D; Prescot, AP; Renshaw, PF; Wang, L | 1 |
| Dasarathy, S; Gruca, LL; Kalhan, SC; Kasumov, T | 1 |
| Beal, R; Eberhardt, RT; Handy, D; Holbrook, M; Jahangir, E; Loscalzo, J; Palmisano, J; Vita, JA | 1 |
| Fujinawa, J; Ganapathy, V; Hosoya, K; Kasai, Y; Tachikawa, M; Terasaki, T; Yokoyama, R | 1 |
| Béard, E; Braissant, O; Henry, H; Torrent, C | 1 |
| Coons, SW; Nieman, RA; Pfisterer, WK; Preul, MC; Scheck, AC; Spetzler, RF | 1 |
| O'Brien, WE; Sun, Q | 1 |
| ASKONAS, BA; STERN, K | 1 |
| Brosnan, JT; Brosnan, ME | 1 |
| Angley, MT; Gerber, JP; McKinnon, RA; Sorich, MJ; Wang, L; Young, RL | 1 |
| Briand, G; Feki, M; Kaabachi, N; Nasrallah, F | 1 |
| Kolling, J; Wyse, AT | 1 |
| Casey, B; Connolly, MB; Davis, C; Horvath, GA; Jakobs, C; Lowry, N; Mercimek-Mahmutoglu, S; Poskitt, KJ; Salomons, GS; Sinclair, G; Stockler-Ipsiroglu, S | 1 |
| Ardon, O; Longo, N; Pasquali, M; Schwartz, E; Vanzo, R | 1 |
| Aarsen, FK; de Coo, IF; de Klerk, JB; Huijmans, JG; Jakobs, C; Knol, DL; Mancini, GM; Pouwels, PJ; Salomons, GS; ten Hoopen, LW; van de Kamp, JM; van der Knaap, MS | 1 |
| Afenjar, A; Barbier, V; Boddaert, N; Chabli, A; Cheillan, D; de Keyzer, Y; de Lonlay, P; Desguerre, I; Jakobs, C; Mazzuca, M; Munnich, A; Philippe, A; Salomons, GS; Valayannopoulos, V | 1 |
| Boenzi, S; Di Ciommo, VM; Dionisi-Vici, C; Goffredo, BM; la Marca, G; Martinelli, D; Rizzo, C | 1 |
| Brosnan, JT; Brosnan, ME; Brown, C; da Silva, RP; Deminice, R; Furey, GN; Jacobs, RL; Jordao, AA; Kelly, KB; King-Jones, K; Lamarre, SG; McCarter, SA | 1 |
| Baĭsa, AE; Burov, SV; Chefu, SG; Leko, MV; Veselkina, OS; Vlasov, TD | 1 |
| Osaka, H; Shimbo, H; Wada, T | 1 |
| Buyse, J; De Smet, S; Dierick, NA; Lemme, A; Maertens, L; Michiels, J; Rademacher, M | 1 |
| Braissant, O | 2 |
| Barkovich, JA; Betsalel, OT; Jakobs, C; Johnston, K; Ndika, JD; O'Neill, P; Salomons, GS; Wirt, MD | 1 |
| Gong, Q; Isobe, T; Li, J; Liu, M; Matsumura, A; Quan, H; Xing, H; Yang, Z; Yue, Q | 1 |
| Li, W; Liang, YJ; Wang, HP; Wu, YJ; Yang, L | 1 |
| Bout, MA; Briand, G; Feki, M; Joncquel-Chevalier Curt, M; Kaabachi, N; Khouja, N; Kraoua, I; Nasrallah, F; Taieb, SH | 1 |
| Bacci, A; Bonora, S; Mucci, A; Righi, V; Schenetti, L; Tugnoli, V | 1 |
| Afenjar, A; Bekri, S; Benoist, JF; Briand, G; Cartault, F; Chabli, A; Chabrol, B; Cheillan, D; Cuisset, JM; Deiva, K; Delorme, R; Dobbelaere, D; Douay, O; Gerard, M; Goldenberg, A; Héron, D; Joncquel-Chevalier Curt, M; Lion-François, L; Mention-Mulliez, K; Pinard, JM; Pitelet, G; Porchet, N; Portes, VD; Prieur, F; Rivier, F; Salomons, GS; Simard, G; Tardieu, M; Valayannopoulos, V; Vamecq, J; Vianey-Saban, C | 1 |
| Aksentijevic, D; Balaban, RS; Channon, KM; Clarke, K; Dawson, D; de Bono, JP; Hunyor, I; Lygate, CA; Medway, DJ; Neubauer, S; Phillips, D; Sebag-Montefiore, L; ten Hove, M; Watkins, H; Zervou, S | 1 |
| Niess, B; Obrenovic, M; Ostojic, SM; Stojanovic, M | 1 |
| Aziz, K; Brosnan, JT; Brosnan, ME; Edison, EE | 1 |
| Aldámiz-Echevarría, L; Andrade, F; Asla, I; Echeverría, J; Lage, S; Luz Couce, M; Prieto, JA; Rodríguez, A; Ruiz, N; Sanjurjo, P | 1 |
| Barshop, BA; El-Gharbawy, AH; Goldstein, JL; Koeberl, DD; Millington, DS; Schlune, A; Schulze, A; Vaisnins, AE; Young, SP | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; McGowan, RA | 1 |
| Furlan, AC; Moreira, I; Murakami, AE; Ospina-Rojas, IC; Picoli, KP; Rodrigueiro, RJ | 1 |
| Amedjout, N; Boulahdour, N; Cheillan, D; Hamadouche, T; Kessaci, F; Nouioua, S; Salomons, GS; Tazir, M; Zaouidi, S | 1 |
| Atzori, L; Fanos, V; Lanari, M; Lazzarotto, T; Locci, E; Manzoni, P; Noto, A | 1 |
| Afenjar, A; Bekri, S; Benoist, JF; Briand, G; Cartault, F; Chabli, A; Chabrol, B; Cheillan, D; Cuisset, JM; Deiva, K; Delorme, R; Des Portes, V; Dobbelaere, D; Douay, O; Gerard, M; Goldenberg, A; Héron, D; Joncquel-Chevalier Curt, M; Lion-François, L; Mention-Mulliez, K; Pinard, JM; Pitelet, G; Porchet, N; Prieur, F; Rivier, F; Salomons, GS; Simard, G; Tardieu, M; Valayannopoulos, V; Vamecq, J; Vianey-Saban, C | 1 |
| Brosnan, JT; Brosnan, ME; Clow, K; da Silva, RP | 1 |
| Harris, RM; Kharbanda, KK; Moats, JC; Osna, NA; Thomes, PG; Todero, SL; Tuma, DJ | 1 |
| Angle, B; Araújo, HC; Barshop, B; Coskun, T; Diogo, L; Geraghty, M; Grolik, C; Haliloglu, G; Konstantopoulou, V; Korenke, GC; Leuzzi, V; Levtova, A; Longo, N; Mackenzie, J; Maranda, B; Marquart, I; Mercimek-Mahmutoglu, S; Mhanni, AA; Mitchell, G; Morris, A; Newlove, T; Nyhan, W; Renaud, D; Scaglia, F; Schlune, A; Schulze, A; Stockler-Ipsiroglu, S; Valayannopoulos, V; van Karnebeek, C; van Spronsen, FJ; Verbruggen, KT; Yuskiv, N | 1 |
| DeBiase, I; Jensen, M; Longo, N; Pasquali, M; Randall, H; Schwarz, E; Yuzyuk, T | 1 |
| da Cunha, SF; de Freitas, EC; Deminice, R; Franco, GS; Jordao, AA; Rosa, FT | 1 |
| Anninos, A; Burgard, P; Gan-Schreier, H; Haas, D; Haege, G; Hoffmann, GF; Langhans, CD; Okun, JG; Schulze, A | 1 |
| Nguyen, T; Pitt, JJ; Tzanakos, N | 1 |
| Abdullah, O; Bogdanov, VB; Bogdanova, OV; Kanekar, S; Prescot, AP; Renshaw, PF | 1 |
| Drid, P; Hoffman, JR; Ostojic, SM; Stojanovic, M | 1 |
| Cedazo-Mínguez, Á; Cifuentes, A; Ibáñez, C; Lodeiro, M; Simó, C | 1 |
| Berg, JP; Birkeland, KI; Bærug, A; Jenum, AK; Nakstad, B; Sachse, D; Sletner, L | 1 |
| Amayreh, W; Das, AM; Meyer, U | 1 |
| Auray-Blais, C; Lavoie, P; Maranda, B | 1 |
| Ostojic, SM; Vojvodic-Ostojic, A | 1 |
| Ostojic, SM; Stojanovic, M | 1 |
| Béard, E; Braissant, O; Hanna-El-Daher, L; Henry, H; Tenenbaum, L | 1 |
| Bertolo, RF; Brunton, JA; Furlong, KR; McBreairty, LE; Robinson, JL | 1 |
| Collet, JP; Dunbar, M; Edgar, V; Elango, R; Jaggumantri, S; Mignone, C; Newlove, T; Sargent, M; Stockler-Ipsiroglu, S; van Karnebeek, CD | 1 |
| Ostojic, SM | 8 |
| Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Liu, X; Parvez, F; Peters, BA; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Ghasemi, K; Khanmohammadi, M; Saligheh Rad, H | 1 |
| Baumgarten, TJ; Butz, M; Hoogenboom, N; Oeltzschner, G; Schnitzler, A; Wittsack, HJ | 1 |
| Apatean, D; Battini, R; DeBrosse, S; Dessoffy, K; Dowling, MD; Edvardson, S; Eichler, F; Johnston, K; Koeller, DM; Nouioua, S; Stockler-Ipsiroglu, S; Tazir, M; Verma, A; Wierenga, AM; Wierenga, KJ; Wong, LJ; Zhang, V | 1 |
| Drid, P; Hoffman, JR; Ostojic, SM; Sekulic, D; Stojanovic, M; Zenic, N | 1 |
| Halas, V; Lemme, A; Németh, K; Rademacher, M; Tossenberger, J | 1 |
| Drid, P; Ostojic, J; Ostojic, SM | 1 |
| Drid, P; Jovanov, P; Ostojic, J; Ostojic, SM; Vranes, M | 1 |
| Deldicque, L; Francaux, M | 1 |
| Drid, P; Ostojic, J; Ostojic, SM; Vranes, M | 1 |
| Bezard, M; Brunotto, M; Dodelson de Kremer, R; Martínez, LD | 1 |
| Charismiadou, M; Deligeorgis, SG; Fotakis, C; Goliomytis, M; Lantzouraki, DZ; Simitzis, PE; Zoumpoulakis, P | 1 |
| Baharom, S; Bruce, CR; De Matteo, R; Della Gatta, P; Dickinson, H; Ellery, S; Hale, N; Harding, R; Kowalski, GM; Snow, RJ; Walker, D | 1 |
| Bertolo, RF; Brunton, JA; Dinesh, OC | 2 |
| Fukaya, M; Hosoya, KI; Sakai, K; Tachikawa, M; Terasaki, T; Watanabe, M | 1 |
| Loncar, D; Ostojic, SM; Sekulic, D; Vranes, M; Zenic, N | 1 |
| Aydin, HI | 1 |
| Kocic, V; Ostojic, SM; Stajer, V; Vranes, M | 1 |
| Bandeira, AO; Bruun, TUJ; Debray, FG; Ficicioglu, C; Goldstein, J; Joost, K; Koeberl, DD; Luísa, D; Mercimek-Andrews, S; Nassogne, MC; O'Sullivan, S; Õunap, K; Salomons, GS; Schulze, A; Sidky, S; van Maldergem, L | 1 |
| Gai, XR; He, DT; Lai, WQ; Li, JT; Sun, XL; Yang, LB; Zhang, LY | 1 |
| Gadžurić, S; Jovanov, P; Marić, A; Ostojić, S; Panić, J; Sakač, M; Vraneš, M | 1 |
| Ostojic, J; Ostojic, SM; Semeredi, S; Stajer, V; Vranes, M | 1 |
| Fu, Y; Gao, F; Jiang, Y; Li, J; Li, Y; Zhang, L; Zhou, G | 1 |
| Gao, F; Li, JL; Wang, XF; Zhang, L; Zhou, GH; Zhu, XD | 1 |
| Braun, U; DeGroot, AA; Dilger, RN | 1 |
| Benoit, R; Boutin, J; Brigitte, C; Dominique, D; Isabelle, RV; Samir, M; Samuel, A | 1 |
| Dong, B; He, D; Lai, W; Li, J; Yang, L; Zhang, L | 1 |
| Bosch, G; Braun, U; Hendriks, WH; van der Poel, AFB | 1 |
| Bertolo, RF; Brunton, JA; Martin, GM; McBreairty, LE; Randunu, R; Robinson, JL; Ryan, RA; Walsh, CJ | 1 |
| Ahmed, S; George, C; Henkelman, M; Naufer, A; Schulze, A; Sinha, A; Tkachyova, I; Tsagaris, M; van Eede, M; von Both, I | 1 |
| Ardalan, M; Batista, ED; Titgemeyer, EC | 1 |
| Adriano, E; Balestrino, M | 1 |
| Arning, E; Ashcraft, P; Bottiglieri, T; Brown, M; Gibson, KM; Jansen, E; Kirby, T; Rinaldo, P; Roullet, JB; Salomons, GS; Turgeon, C; Walters, DC | 1 |
| Arunachalam, P; Choe, CU; Gelderblom, M; Gerloff, C; Jensen, M; Magnus, T; Müller, C; Schwedhelm, E; Zeller, T | 1 |
| Choe, CU; Gerloff, C; Hornig, S; Isbrandt, D; Neu, A; Sasani, A; Schwedhelm, E; Tsikas, D | 1 |
| Braun, U; Cahaner, A; Epstein, T; Gravitz, D; Rademacher, M; Reicher, N; Uni, Z | 1 |
| Pearl, KA; Speer, HF; Titgemeyer, EC | 1 |
| Braun, U; De Smet, S; Golian, A; Kermanshahi, H; Lemme, A; Majdeddin, M; Michiels, J | 1 |
| Acs, P; Betlehem, J; Olah, A; Ostojic, SM; Ratgeber, L | 1 |
| Chen, JZ; Guo, G; Huo, WJ; Liu, Q; Liu, YJ; Wang, C; Wang, DH; Wu, MJ; Wu, ZZ; Zhang, J; Zheng, C | 1 |
| Ferraro, TN; Gaughan, J; Hackmyer, C; Khadeer, M; Lovett, J; McGarry, A; Moaddel, R; Pradhan, B; Shaikh, H; Wainer, IW | 1 |
| Bertolo, RF; Brunton, JA; Dinesh, OC; Kankayaliyan, T; Rademacher, M; Tomlinson, C | 1 |
| Allsop, J; Baburamani, AA; Ciarrusta, J; De Vita, E; Dimitrova, R; Hughes, E; Kangas, J; Long, KR; McAlonan, GM; Patkee, PA; Rutherford, MA | 1 |
| Cheng, X; Gao, W; Jiang, M; Leng, X; Li, M; Lu, X; Tian, J; Wen, H; Wu, F; Yu, L; Zhang, W | 1 |
| Braun, U; Portocarero, N | 1 |
| Korovljev, D; Nesic, N; Ostojic, J; Ostojic, SM; Seper, V; Stajer, V; Todorovic, N | 1 |
| Ostojic, SM; Stajer, V; Todorovic, N | 1 |
| Jezdimirovic, T; Ostojic, J; Ostojic, SM; Stajer, V; Zanini, D | 1 |
| Cadogan, DJ; Chrystal, PV; Inhuber, V; McGilchrist, P; Moss, AF; Sharma, NK; Wilkinson, SJ | 1 |
| Cai, W; Li, X; Ma, C; Pan, J; Wang, C; Yang, K; Zang, C; Zhang, S | 1 |
| Akanuma, SI; Hosoya, KI; Jomura, R; Kubo, Y; Tachikawa, M | 1 |
| Andjic, MM; Bolevich, S; Draginic, ND; Jakovljevic, VLJ; Jeremic, JN; Milinkovic, MV; Pantovic, SB; Prokic, VZ; Rankovic, MR; Sretenovic, JZ; Zivkovic, VI | 1 |
| Liu, N; Sun, Q | 1 |
| Beckmann, B; Blau, LS; Dimina, L; Finkel, A; Jantz, M; Lützow, M; Maassen, N; Mariotti, F; Röhrig, MA; Shushakov, V; Thorns, A; Tsikas, D | 1 |
| Chai, X; Cheng, S; Cong, X; Hu, Y; Men, J; Qiao, Z; Rao, S | 1 |
Reviews
15 review(s) available for creatine and glycine
| Article | Year |
|---|---|
Creatine: biosynthesis, regulation, and function.
Topics: Amidinotransferases; Animals; Arginine; Creatine; Diet, Vegetarian; Enzyme Repression; Glycine; Guanidines; Humans; Liver; Male; Methyltransferases; Phosphocreatine; S-Adenosylmethionine; Substrate Specificity; Transferases | 1979 |
Dietary factors influencing amino acid degradation.
Topics: Amino Acids; Aminoisobutyric Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginase; Arginine; Chickens; Creatine; Diet; Feces; Glycine; Kidney; Lysine; Nutritional Requirements; Rats; Serine; Urea | 1972 |
Clinical characteristics and diagnostic clues in inborn errors of creatine metabolism.
Topics: Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Metabolism, Inborn Errors; Methyltransferases; Mutation | 2003 |
Laboratory diagnosis of defects of creatine biosynthesis and transport.
Topics: Biological Transport; Creatine; Diagnostic Tests, Routine; Glycine; Humans; Mutation | 2005 |
AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: a review.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Creatine; Developmental Disabilities; Genetic Predisposition to Disease; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Intellectual Disability; Language Development Disorders; Membrane Transport Proteins; Movement Disorders; Phenotype; Prognosis; Speech Disorders | 2008 |
Cerebral creatine deficiency syndromes: clinical aspects, treatment and pathophysiology.
Topics: Adult; Amidinotransferases; Animals; Brain Diseases, Metabolic, Inborn; Cerebellar Diseases; Child; Child, Preschool; Creatine; Creatinine; Diagnosis, Differential; Female; Genetic Diseases, X-Linked; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Male; Nerve Tissue Proteins; Plasma Membrane Neurotransmitter Transport Proteins; Syndrome | 2007 |
Pre-symptomatic treatment of creatine biosynthesis defects.
Topics: Amidinotransferases; Brain Diseases, Metabolic; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Humans | 2007 |
Creatine and guanidinoacetate transport at blood-brain and blood-cerebrospinal fluid barriers.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Cerebrospinal Fluid; Creatine; Glycine; Humans | 2012 |
Cellular bioenergetics of guanidinoacetic acid: the role of mitochondria.
Topics: Animals; Biological Transport, Active; Creatine; Creatine Kinase; Cytosol; Energy Metabolism; Glycine; Humans; Mitochondria | 2015 |
Potential harmful effects of dietary supplements in sports medicine.
Topics: Alkaloids; Amines; Creatine; Dietary Supplements; Drug Contamination; Drug Interactions; Drug Overdose; Endocrine Disruptors; Estrogens; Glycine; Humans; Nitrates; Sports; Sports Medicine; Tetrahydroisoquinolines; Triazines; Weight Loss | 2016 |
Tackling guanidinoacetic acid for advanced cellular bioenergetics.
Topics: Creatine; Energy Metabolism; GABA Plasma Membrane Transport Proteins; Glycine; Humans; Membrane Glycoproteins; Membrane Transport Proteins | 2017 |
Benefits and drawbacks of guanidinoacetic acid as a possible treatment to replenish cerebral creatine in AGAT deficiency.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Clinical Trials as Topic; Creatine; Developmental Disabilities; Glycine; Humans; Intellectual Disability; Speech Disorders; Treatment Outcome | 2019 |
Guanidinoacetic acid deficiency: a new entity in clinical medicine?
Topics: Creatine; Energy Metabolism; Glycine; Humans; Metabolic Diseases | 2020 |
The physiological role of guanidinoacetic acid and its relationship with arginine in broiler chickens.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Creatine; Diet; Dietary Supplements; Glycine | 2021 |
Safety of Dietary Guanidinoacetic Acid: A Villain of a Good Guy?
Topics: Aged; Animals; Creatine; Dietary Supplements; Energy Metabolism; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Risk Assessment | 2021 |
Trials
24 trial(s) available for creatine and glycine
| Article | Year |
|---|---|
Creatine corrects muscle 31P spectrum in gyrate atrophy with hyperornithinaemia.
Topics: Adolescent; Adult; Child; Creatine; Dietary Supplements; Female; Glycine; Gyrate Atrophy; Humans; Magnetic Resonance Spectroscopy; Male; Methionine; Middle Aged; Muscle, Skeletal; Ornithine; Phosphorus Isotopes | 1999 |
Effect of cisplatin treatment on the urinary excretion of guanidinoacetic acid, creatinine and creatine in patients with urinary tract neoplasm, and on superoxide generation in human neutrophils.
Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Creatine; Creatinine; Female; Glycine; Humans; Kidney; Male; Middle Aged; Neutrophils; Superoxides; Urologic Neoplasms | 2000 |
Plasma guanidino compounds are altered by oral creatine supplementation in healthy humans.
Topics: Adaptation, Physiological; Administration, Oral; Arginine; Creatine; Dietary Supplements; Double-Blind Method; Female; Glycine; Guanidines; Humans; Male | 2004 |
Guanidino compounds after creatine supplementation in renal failure patients and their relation to inflammatory status.
Topics: Administration, Oral; Aged; Arginine; Biomarkers; C-Reactive Protein; Creatine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Follow-Up Studies; Glycine; Guanidines; Humans; Inflammation; Male; Nephelometry and Turbidimetry; Prognosis; Renal Dialysis; Renal Insufficiency; Severity of Illness Index; Succinates; Treatment Outcome; Urea | 2008 |
Oral glycine administration increases brain glycine/creatine ratios in men: a proton magnetic resonance spectroscopy study.
Topics: Administration, Oral; Adult; Brain; Creatine; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Protons | 2009 |
The effect of L-arginine and creatine on vascular function and homocysteine metabolism.
Topics: Aged; Arginine; Brachial Artery; Coronary Artery Disease; Creatine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Hyperemia; Male; Methionine; Middle Aged; Regional Blood Flow; Treatment Outcome; Ultrasonography; Vasodilation | 2009 |
Supplementation of guanidinoacetic acid to broiler diets: effects on performance, carcass characteristics, meat quality, and energy metabolism.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Chickens; Creatine; Diet; Dietary Supplements; Energy Metabolism; Glycine; Male; Oxidative Stress | 2012 |
Creatine metabolism and safety profiles after six-week oral guanidinoacetic acid administration in healthy humans.
Topics: Administration, Oral; Adult; Creatine; Creatinine; Dietary Supplements; Female; Glycine; Humans; Male | 2013 |
Short-term creatine supplementation does not reduce increased homocysteine concentration induced by acute exercise in humans.
Topics: Adolescent; Creatine; Cysteine; Dietary Supplements; Double-Blind Method; Energy Intake; Exercise; Feeding Behavior; Folic Acid; Glycine; Healthy Volunteers; Homocysteine; Humans; Male; Methionine; S-Adenosylmethionine; Soccer; Vitamin B 12 | 2014 |
Dose-response effects of oral guanidinoacetic acid on serum creatine, homocysteine and B vitamins levels.
Topics: Administration, Oral; Creatine; Creatinine; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Glycine; Homocysteine; Humans; Male; Vitamin B Complex; Young Adult | 2014 |
Single-dose oral guanidinoacetic acid exhibits dose-dependent pharmacokinetics in healthy volunteers.
Topics: Administration, Oral; Adult; Area Under Curve; Creatine; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glycine; Healthy Volunteers; Humans; Male; Young Adult | 2015 |
Guanidinoacetic acid loading affects plasma γ-aminobutyric acid in healthy men.
Topics: Administration, Oral; Adult; Creatine; Dietary Supplements; Double-Blind Method; Down-Regulation; Fasting; gamma-Aminobutyric Acid; Glutamine; Glycine; Humans; Male; Pilot Projects; Young Adult | 2015 |
Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial.
Topics: Adult; Bangladesh; Biomarkers; Cohort Studies; Creatine; Dietary Supplements; Double-Blind Method; Down-Regulation; Female; Folic Acid; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Intention to Treat Analysis; Male; Middle Aged; Patient Dropouts; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Supplementation with Guanidinoacetic Acid in Women with Chronic Fatigue Syndrome.
Topics: Adult; Creatine; Dietary Supplements; Fatigue; Fatigue Syndrome, Chronic; Female; Glycine; Humans; Middle Aged; Muscle Strength; Muscles; Musculoskeletal Pain; Physical Exertion; Treatment Outcome | 2016 |
Dietary guanidinoacetic acid increases brain creatine levels in healthy men.
Topics: Adult; Aspartic Acid; Biomarkers; Brain; Cerebellum; Creatine; Dietary Supplements; Down-Regulation; Follow-Up Studies; Glycine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Methylation; Neuroimaging; Neurons; Performance-Enhancing Substances; Protein Processing, Post-Translational; Thalamus; Toxicity Tests, Acute; Young Adult | 2017 |
Guanidinoacetic acid versus creatine for improved brain and muscle creatine levels: a superiority pilot trial in healthy men.
Topics: Adult; Biomarkers; Creatine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Follow-Up Studies; Frontal Lobe; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Spectroscopy; Male; Middle Cerebellar Peduncle; Neurons; Performance-Enhancing Substances; Pilot Projects; Quadriceps Muscle; Serbia; Up-Regulation; Young Adult | 2016 |
Guanidinoacetic acid with creatine compared with creatine alone for tissue creatine content, hyperhomocysteinemia, and exercise performance: A randomized, double-blind superiority trial.
Topics: Adult; Biomarkers; Brain; Creatine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Drug Combinations; Energy Metabolism; Exercise; Glycine; Humans; Hyperhomocysteinemia; Male; Muscle Strength; Muscle, Skeletal; Physical Endurance; Reference Values; Resistance Training; Weight Gain; Young Adult | 2019 |
Effects of guanidinoacetic acid on growth performance, creatine metabolism and plasma amino acid profile in broilers.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Creatine; Diet; Dietary Supplements; Glycine; Male; Random Allocation | 2019 |
Guanidinoacetic acid loading for improved location-specific brain creatine.
Topics: Brain; Cerebellum; Creatine; Dietary Supplements; Energy Metabolism; Glycine; Gray Matter; Healthy Volunteers; Humans; Magnetic Resonance Spectroscopy; Male; Thalamus; White Matter; Young Adult | 2021 |
Neonatal Piglets Can Synthesize Adequate Creatine, but Only with Sufficient Dietary Arginine and Methionine, or with Guanidinoacetate and Excess Methionine.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Arginine; Creatine; Diet; Drug Tapering; Female; Glycine; Isotope Labeling; Male; Methionine; Phenylalanine; Swine; Tyrosine | 2021 |
Guanidinoacetate-Creatine Supplementation Improves Functional Performance and Muscle and Brain Bioenergetics in the Elderly: A Pilot Study.
Topics: Aged; Biomarkers; Brain; Cognition; Creatine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Energy Metabolism; Female; Glycine; Healthy Volunteers; Humans; Male; Muscle, Skeletal; Muscles; Physical Functional Performance; Pilot Projects; Proton Magnetic Resonance Spectroscopy | 2021 |
Effects of dietary guanidinoacetic acid on growth performance, guanidinoacetic acid absorption and creatine metabolism of lambs.
Topics: Animal Feed; Animals; Chickens; Creatine; Diet; Dietary Supplements; Energy Metabolism; Glycine; Male; Sheep; Sheep, Domestic | 2022 |
Guanidinoacetic acid provides superior cardioprotection to its combined use with betaine and (or) creatine in HIIT-trained rats.
Topics: Animals; Betaine; Creatine; Glycine; High-Intensity Interval Training; Hydrogen Peroxide; Male; Rats; Rats, Wistar | 2022 |
Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise.
Topics: Arginine; Citrulline; Creatine; Creatinine; Dietary Supplements; Glutamates; Glutamine; Glycine; Homoarginine; Humans; Lysine; Male; Malondialdehyde; Methyltransferases; Nitrates; Nitrites; Ornithine; Phenylalanine; Sarcosine; Sodium Chloride; Tryptophan; Tyrosine | 2022 |
Other Studies
252 other study(ies) available for creatine and glycine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |
Nitrogen retention in rats fed on diets enriched with arginine and glycine. 1. Improved N retention after trauma.
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Creatine; Food, Fortified; Glycine; Hindlimb; Liver; Nitrogen; Nutritional Physiological Phenomena; Rats; Time Factors; Urea | 1977 |
The effect of a meal of meat on glomerular filtration rate in dogs at normal urine flows.
Topics: Animals; Creatine; Creatinine; Dogs; Female; Glomerular Filtration Rate; Glycine; Hematocrit; Meat; Metabolic Clearance Rate | 1976 |
Clinical test of renal guanidinoacetic acid metabolism by oral citrulline and creatine loading.
Topics: 17-Ketosteroids; Amidinotransferases; Animals; Chronic Disease; Citrulline; Creatine; Diabetes Mellitus, Type 2; Female; Glomerulonephritis; Glycine; Humans; Kidney; Kidney Tubules, Proximal; Middle Aged; Ovariectomy; Rats; Rats, Inbred WKY | 1992 |
The effect of guanidino substances from uremic plasma on insulin binding to erythrocyte receptors in uremia.
Topics: Adult; Creatine; Creatinine; Down-Regulation; Erythrocytes; Female; Glycine; Guanidines; Humans; Insulin; Male; Middle Aged; Receptor, Insulin; Renal Dialysis; Urea; Uremia | 1991 |
Clinical analysis in intact erythrocytes using 1H spin echo NMR.
Topics: Adult; Arthritis, Rheumatoid; Choline; Creatine; Cytosol; Ergothioneine; Erythrocytes; Female; Glutathione; Glycine; Graves Disease; Humans; Indomethacin; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oxidation-Reduction; Spectrum Analysis; Sulfhydryl Compounds; Time Factors | 1991 |
Contribution of high concentrations of PTH(1-34) to muscle weakness in uremia by suppression of guanidinoacetic acid synthesis.
Topics: Animals; Creatine; Glycine; In Vitro Techniques; Kidney Tubules; Muscles; Parathyroid Hormone; Peptide Fragments; Rats; Teriparatide; Uremia | 1991 |
Prevention of 11-deoxycorticosterone-salt-induced glomerular hypertrophy and glomerulosclerosis by dietary phosphate binder.
Topics: Aluminum Hydroxide; Animals; Antacids; Blood Pressure; Calcium; Creatine; Desoxycorticosterone; Disease Models, Animal; Glomerular Filtration Rate; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Glycine; Hematocrit; Hypertrophy; Kidney Glomerulus; Male; Myocardium; Phosphates; Proteinuria; Rats; Rats, Inbred Strains; Spleen | 1990 |
Effects of monosaccharides and disaccharides on the formation of food mutagens in model systems.
Topics: Chromatography, High Pressure Liquid; Creatine; Creatinine; Disaccharides; Ethylene Glycols; Food; Glycine; Hot Temperature; Maillard Reaction; Monosaccharides; Mutagenicity Tests; Mutagens; Quinoxalines; Salmonella; Temperature | 1990 |
Biochemical mechanisms of oxfenicine cardiotoxicity.
Topics: Adenosine Triphosphatases; Animals; Calcium; Creatine; Creatine Kinase; Female; Glycine; Heart; Kidney; Lipid Metabolism; Liver; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Myocardium; Oxidative Phosphorylation; Rats | 1988 |
Multiple forms of rat kidney L-arginine:glycine amidinotransferase.
Topics: Amidinotransferases; Animals; Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Creatine; Glycine; Immunosorbent Techniques; Isoelectric Focusing; Kidney; Male; Rats | 1988 |
Coronary hyperemia and cardiac hypertrophy following inhibition of fatty acid oxidation. Evidence of a regulatory role for cytosolic phosphorylation potential.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Creatine; Cytosol; Dogs; Fatty Acids; Glycine; Hemodynamics; Isoproterenol; Organ Size; Oxidation-Reduction; Oxygen Consumption; Palmitates; Phosphocreatine; Phosphorylation | 1985 |
[Metabolism of guanidinoacetic acid and creatine in uremia].
Topics: Animals; Creatine; Female; Glycine; Glycine Transaminase; Guanidines; Humans; Kidney; Male; Middle Aged; Muscles; Pancreas; Propionates; Rabbits; Renal Dialysis; Transaminases; Uremia | 1988 |
Methylmalonic aciduria and propionic acidaemia studied by proton nuclear magnetic resonance spectroscopy.
Topics: Amino Acid Metabolism, Inborn Errors; Betaine; Creatine; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Infant; Infant, Newborn; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Malonates; Methylmalonic Acid; Propionates | 1986 |
[Administration of creatine for several days: its effects on increased creatinuria (author's transl)].
Topics: Adult; Aged; Amidinotransferases; Arginine; Creatine; Enzyme Repression; Female; Glycine; Humans; Male; Middle Aged; Time Factors | 1974 |
[Assimilation of creatinine, creatine and guanidoacetic acid by Ceratocystis stenoceras strain IP 1013-70 (F. Mariat) (author's transl)].
Topics: Ascomycota; Biological Evolution; Creatine; Creatinine; Glycine; Guanidines; Sporothrix; Thiamine | 1974 |
Amino acid utilization during total parenteral nutrition in the surgical neonate.
Topics: Administration, Oral; Amino Acids; Blood Urea Nitrogen; Creatine; Glucose; Glycine; Humans; Infant, Newborn; Leucine; Lysine; Metabolic Clearance Rate; Nitrogen; Parenteral Nutrition; Phenylalanine; Valine | 1973 |
Photoreduction of dyes catalysed by organic and bio-molecules.
Topics: Amino Acids; Catalysis; Creatine; Edetic Acid; Electrodes; Free Radicals; Glycine; Hydrogen-Ion Concentration; Light; Magnesium; Methylene Blue; Oxidation-Reduction; Photochemistry; Potentiometry; Spectrophotometry | 1974 |
Arginine and creatine interrelationships in the chick.
Topics: Aminoisobutyric Acids; Animals; Arginase; Arginine; Caseins; Chickens; Creatine; Creatinine; Diet; Feces; Glycine; Kidney; Liver; Lysine; Transaminases; Urea | 1972 |
Effect of dietary protein on glycine amidinotransferase activity in lactating rat tissue.
Topics: Amidinotransferases; Animals; Creatine; Creatinine; Dietary Proteins; Female; Glycine; Kidney; Lactation; Mammary Glands, Animal; Pancreas; Pregnancy; Rats | 1973 |
Stimulation of insulin secretion by guanidinoacetic acid and other guanidine derivatives.
Topics: Amino Acids; Animals; Arginine; Atropine; Carbachol; Creatine; Glycine; Guanidines; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Perfusion; Rats; Stimulation, Chemical | 1970 |
Distribution of creatine, guanidinoacetate and the enzymes for their biosynthesis in the animal kingdom. Implications for phylogeny.
Topics: Acetates; Animals; Annelida; Arginine; Biological Evolution; Canavanine; Carbon Isotopes; Chordata, Nonvertebrate; Creatine; Echinodermata; Glycine; Guanidines; Invertebrates; Methyltransferases; Organ Specificity; S-Adenosylmethionine; Species Specificity; Transferases; Vertebrates | 1972 |
Amino acid, creatine and creatinine studies in myotonic dystrophy.
Topics: Adult; Age Factors; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Creatinine; Erythrocytes; Female; Glutamine; Glycine; Hemolysis; Humans; Male; Membranes; Middle Aged; Myotonic Dystrophy; Ornithine; Permeability; Serine; Threonine | 1972 |
Distribution of creatine, guanidinoacetate and enzymes for their biosynthesis in the animal kingdom. Implications for phylogeny.
Topics: Acetates; Amidines; Animals; Anura; Arginine; Biological Evolution; Carbon Isotopes; Chickens; Chromatography, Paper; Creatine; Fishes; Fresh Water; Glycine; Guanidines; Humans; Male; Methyltransferases; Rats; S-Adenosylmethionine; Seawater; Sharks; Transferases; Turtles; Vertebrates | 1972 |
Relationship of arginine and methionine to creatine formation in chicks.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Chickens; Choline; Choline Deficiency; Creatine; Cystine; Deficiency Diseases; Depression, Chemical; Folic Acid; Folic Acid Deficiency; Glycine; Glycine max; Guanidines; Lipid Metabolism; Liver; Male; Methionine; Muscles; Ornithine; Stimulation, Chemical; Urea; Vitamin B 12; Vitamin B 12 Deficiency; Zea mays | 1971 |
Reduced renal arginine-glycine transamidinase activity in myotonic goats and in patients with myotonic muscular dystrophy.
Topics: Acetates; Adult; Aged; Animals; Arginine; Autopsy; Biopsy; Creatine; Disease Models, Animal; Glycine; Goats; Guanine; Humans; Kidney; Male; Muscular Dystrophies; Myotonia; Transferases | 1969 |
[Transamidinase].
Topics: Amino Acids; Animals; Arginine; Cats; Chemical Phenomena; Chemistry; Chickens; Creatine; Dogs; Glycine; Humans; Hydrogen-Ion Concentration; Hypophysectomy; Kidney; Kidney Diseases; Liver; Methods; Mice; Rats; Temperature; Transferases; Vitamin E Deficiency | 1970 |
Accumulation of 2-aminoimidazole by Streptomyces eurocidicus.
Topics: Amines; Ammonium Chloride; Anti-Bacterial Agents; Arginine; Asparagine; Chromatography, Paper; Creatine; Creatinine; Glucose; Glutamine; Glycine; Histidine; Imidazoles; Nucleosides; Spectrophotometry; Streptomyces | 1970 |
[Effect of substrate supply on post-asphyctic restoration of adenine nucleotides in rabbit hearts in vivo].
Topics: Adenine; Adenine Nucleotides; Animals; Asparagine; Asphyxia; Creatine; Folic Acid; Formates; Fructose; Glucose; Glutamine; Glycine; Glycogen; Heart; Isotonic Solutions; Lactates; Methods; Myocardium; Nucleosides; Oxalates; Phosphates; Phosphocreatine; Rabbits; Ribose | 1970 |
Relationship of arginine and methionine in the nutrition of the chick and the significance of creatine biosynthesis in their interaction.
Topics: Aminobutyrates; Animal Feed; Animals; Arginine; Betaine; Chickens; Creatine; Diet; Drug Antagonism; Drug Synergism; Glycine; Lysine; Methionine; Muscles; Nutritional Physiological Phenomena; Pyridoxine | 1971 |
Evidence for a dual role of creatine in the regulation of kidney transamidinase activities in the rat.
Topics: Amidines; Animals; Arginine; Body Weight; Creatine; Glycine; Kidney; Liver; Male; Methyltransferases; Rats; Time Factors; Transaminases | 1971 |
Metabolic studies of acetoacetate, pyruvate, lactate and citrate in uremic acidosis.
Topics: Acetoacetates; Acidosis; Analysis of Variance; Chronic Disease; Citrates; Citric Acid Cycle; Creatine; Female; Glycine; Humans; Kidney Function Tests; Lactates; Male; Models, Biological; Pyruvates; Uremia | 1968 |
Renal handling of glycine in primary hyperuricaemia.
Topics: Adult; Creatine; Glycine; Humans; Kidney; Male; Uric Acid | 1966 |
Arginine-lysine antagonism in the chick and its relationship to dietary cations.
Topics: Acetates; Animals; Arginine; Chlorides; Citrates; Creatine; Dietary Proteins; Glutamates; Glycine; Growth; Leucine; Lysine; Potassium; Poultry; Quaternary Ammonium Compounds | 1966 |
Carcass transamidinase activities, in vitro, and rates of creatine synthesis, in vivo, in normal and protein-depleted rats.
Topics: Animals; Arginine; Creatine; Diet; Glucose; Glycine; In Vitro Techniques; Male; Protein Deficiency; Rats; Transaminases | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
Repression of rat kidney L-arginine:glycine amidinotransferase synthesis by creatine at a pretranslational level.
Topics: Amidinotransferases; Animals; Creatine; Diet; Electrophoresis, Polyacrylamide Gel; Fluorometry; Glycine; Immunosorbent Techniques; Kidney; Male; Molecular Weight; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Messenger | 1984 |
Post-traumatic creatinuria.
Topics: Adult; Animals; Creatine; Creatinine; DNA; Female; Fractures, Bone; Glycine; Hindlimb; Humans; Ischemia; Male; Methylhistidines; Middle Aged; Muscles; Nitrogen; Rats; Rats, Inbred Strains; Time Factors; Wounds and Injuries | 1984 |
Decreased activities of glycine and guanidinoacetate methyltransferases and increased levels of creatine in tumor cells.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Ehrlich Tumor; Creatine; Glycine; Glycine N-Methyltransferase; Guanidines; Guanidinoacetate N-Methyltransferase; Isoenzymes; Kidney; Liver; Liver Neoplasms, Experimental; Male; Methionine Adenosyltransferase; Methyltransferases; Mice; Rats; Spleen; Tissue Distribution | 1982 |
Nitrogen retention, muscle creatine and orotic acid excretion in traumatized rats fed arginine and glycine enriched diets.
Topics: Amino Acids; Animals; Arginine; Creatine; Dietary Proteins; Glycine; Laparotomy; Male; Muscles; Nitrogen; Orotic Acid; Rats; Wounds and Injuries | 1981 |
Enzymatic studies on the mechanism of creatinuria in rats with experimental thyrotoxic myopathy and dystrophic mice.
Topics: Amidinotransferases; Animals; Creatine; Enzyme Activation; Glycine; Kidney; Male; Mice; Mice, Inbred C57BL; Muscular Diseases; Rabbits; Rats; Rats, Inbred Strains; Triiodothyronine | 1981 |
Quantitative importance of non-skeletal-muscle N tau-methylhistidine and creatine in human urine.
Topics: Creatine; Creatinine; Glycine; Histidine; Humans; Male; Methylhistidines; Middle Aged; Muscles; Muscular Diseases | 1981 |
Inhibition of arginine-glycine amidinotransferase by ornithine. A possible mechanism for the muscular and chorioretinal atrophies in gyrate atrophy of the choroid and retina with hyperornithinemia.
Topics: Amidinotransferases; Animals; Arginase; Atrophy; Choroid; Creatine; Glycine; Humans; Kidney; Kinetics; Male; Muscles; Ornithine; Ornithine-Oxo-Acid Transaminase; Rats; Retina; Retinal Degeneration; Uveal Diseases | 1980 |
Gyrate atrophy of the choroid and retina with hyperornithinemia. Deficient formation of guanidinoacetic acid from arginine.
Topics: Adolescent; Adult; Amidinotransferases; Arginine; Atrophy; Child; Choroid; Creatine; Female; Glycine; Guanidines; Humans; Male; Ornithine; Retina; Retinal Diseases; Uveal Diseases | 1980 |
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminant Analysis; Female; Glioblastoma; Glioma; Glutamates; Glutamine; Glycine; Humans; Hydrogen; Inositol; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Protons | 1995 |
Guanidino compound metabolism in rats subjected to 20% to 90% nephrectomy.
Topics: Animals; Arginine; Creatine; Glycine; Guanidines; Homoarginine; Kidney; Kidney Failure, Chronic; Male; Nephrectomy; Propionates; Rats; Rats, Sprague-Dawley; Reference Values; Uremia | 1995 |
Age-dependent neurotoxicity of striatal lesions produced by aminooxyacetic acid: quantitative in vitro 1H NMR spectroscopic studies.
Topics: Aging; Alanine; Animals; Aspartic Acid; Corpus Striatum; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; In Vitro Techniques; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Rats; Rats, Sprague-Dawley | 1995 |
Proton magnetic resonance spectroscopy of astrocytic tumors: an in vitro study.
Topics: Antibodies, Monoclonal; Astrocytoma; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Female; Glioma; Glycine; Humans; Immunohistochemistry; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Temporal Lobe | 1993 |
Guanidino compounds in serum and urine of cirrhotic patients.
Topics: Adult; Aged; Amino Acids; Budd-Chiari Syndrome; Creatine; Creatinine; Female; Glycine; Guanidines; Hepatitis; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Reference Values; Regression Analysis; Sex Characteristics; Urea | 1995 |
Cerebral metabolite patterns in dialysis patients: evaluation with H-1 MR spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Glycine; Humans; Inositol; Kidney Failure, Chronic; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis | 1995 |
In situ changes in purine nucleotide and N-acetyl concentrations upon inducing global ischemia in cat brain.
Topics: Acetylation; Adenosine; Animals; Aspartic Acid; Brain Ischemia; Cats; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glycine; Magnetic Resonance Spectroscopy; Male; Purine Nucleotides; Taurine | 1993 |
Childhood adrenoleukodystrophy: assessment with proton MR spectroscopy.
Topics: Adolescent; Adrenoleukodystrophy; Aspartic Acid; Child; Child, Preschool; Choline; Creatine; gamma-Aminobutyric Acid; Genetic Linkage; Glucose; Glutamates; Glutamine; Glycine; Humans; Hydrogen; Inositol; Lipids; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; X Chromosome | 1993 |
Renal handling of guanidino compounds in rat and rabbit.
Topics: Affinity Labels; Animals; Arginine; Creatine; Glycine; Guanidines; Kidney; Male; Methylguanidine; Propionates; Rabbits; Rats; Rats, Sprague-Dawley; Succinates; Tissue Distribution; Urea | 1997 |
Simultaneous determination of creatinine, creatine, and guanidinoacetic acid in human serum and urine using liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
Topics: Atmospheric Pressure; Chromatography, High Pressure Liquid; Creatine; Creatinine; Glycine; Humans; Mass Spectrometry; Time Factors | 1997 |
Metabolism of glycine in primary astroglial cells: synthesis of creatine, serine, and glutathione.
Topics: Animals; Animals, Newborn; Arginine; Astrocytes; Brain; Carbon Isotopes; Cells, Cultured; Creatine; Glutathione; Glycine; Kinetics; Methionine; Nuclear Magnetic Resonance, Biomolecular; Rats; Rats, Wistar; Serine | 1998 |
Creatine metabolism in the seminiferous epithelium of rats. I. Creatine synthesis by isolated and cultured cells.
Topics: Animals; Arginine; Carbon Radioisotopes; Cell Separation; Cells, Cultured; Coculture Techniques; Creatine; Glycine; Male; Rats; Rats, Sprague-Dawley; Seminiferous Epithelium; Sertoli Cells; Spermatozoa | 1998 |
Therapeutic trial of arginine restriction in creatine deficiency syndrome.
Topics: Arginine; Child, Preschool; Creatine; Female; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Metabolism, Inborn Errors; Methyltransferases | 1998 |
An accurate stable isotope dilution gas chromatographic-mass spectrometric approach to the diagnosis of guanidinoacetate methyltransferase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Creatine; Gas Chromatography-Mass Spectrometry; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Methyltransferases; Radioisotope Dilution Technique | 1998 |
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Creatine; Disease Models, Animal; Glycine; Humans; Mice; Mice, Transgenic; Motor Activity; Muscle, Skeletal; Neurons; Neuroprotective Agents; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine; Tyrosine 3-Monooxygenase | 1999 |
Localized 1H NMR measurements of 2-pyrrolidinone in human brain in vivo.
Topics: Adult; Anticonvulsants; Body Water; Creatine; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Glycine; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Phantoms, Imaging; Pyrrolidinones; Treatment Outcome; Vigabatrin | 1999 |
ATP nucleotidylation of creatine kinase.
Topics: Adenosine Triphosphate; Alzheimer Disease; Animals; Azides; Brain Chemistry; Chromatography, High Pressure Liquid; Creatine; Creatine Kinase; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glycine; Humans; Iodoacetates; Isoenzymes; Muscle, Skeletal; Nucleotidyltransferases; Oxidation-Reduction; Peptides; Phosphorus Radioisotopes; Photoaffinity Labels; Rabbits; Substrate Specificity; Temperature; Time Factors; Tromethamine; Trypsin | 1999 |
Glycine improves survival after hemorrhagic shock in the rat.
Topics: Animals; Creatine; Creatine Kinase; Dose-Response Relationship, Drug; Female; Glycine; Injections, Intravenous; Kupffer Cells; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Analysis; Transaminases; Tumor Necrosis Factor-alpha | 1999 |
Guanidinoacetate methyltransferase (GAMT) deficiency: non-invasive enzymatic diagnosis of a newly recognized inborn error of metabolism.
Topics: Amniotic Fluid; Cells, Cultured; Chromatography, High Pressure Liquid; Creatine; Female; Fetal Diseases; Fibroblasts; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Lymphocytes; Male; Metabolism, Inborn Errors; Methyltransferases; Pregnancy; Prenatal Diagnosis; S-Adenosylmethionine; Skin | 2000 |
Mental retardation and behavioral problems as presenting signs of a creatine synthesis defect.
Topics: Aspartic Acid; Body Fluids; Brain Diseases, Metabolic; Child, Preschool; Creatine; Diagnosis, Differential; Epilepsy; Follow-Up Studies; Glycine; Humans; Infant; Intellectual Disability; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Disorders | 2000 |
Two new severe mutations causing guanidinoacetate methyltransferase deficiency.
Topics: Base Sequence; Cells, Cultured; Child, Preschool; Chromatography, High Pressure Liquid; Creatine; Creatinine; DNA Mutational Analysis; Genetic Heterogeneity; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Male; Metabolism, Inborn Errors; Methyltransferases; Mutation; Phenotype; Polymorphism, Restriction Fragment Length; RNA, Messenger | 2000 |
In vivo 1H magnetic resonance spectroscopic measurement of brain glycine levels in nonketotic hyperglycinemia.
Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Chromosome Aberrations; Chromosome Disorders; Creatine; Follow-Up Studies; Genes, Recessive; Glutamic Acid; Glutamine; Glycine; Humans; Hyperglycinemia, Nonketotic; Infant; Infant, Newborn; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male | 2001 |
Analysis of guanidinoacetate and creatine by isotope dilution electrospray tandem mass spectrometry.
Topics: Adult; Child; Child, Preschool; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant, Newborn; Isotopes; Mass Spectrometry; Methyltransferases; Neonatal Screening; Reference Values; Reproducibility of Results | 2001 |
Influence of 72% injury in one kidney on several organs involved in guanidino compound metabolism: a time course study.
Topics: Acute Kidney Injury; Animals; Arginine; Creatine; Creatinine; Glycine; Guanidines; Homoarginine; Kidney; Kidney Failure, Chronic; Male; Methylguanidine; Muscle, Skeletal; Nephrectomy; Propionates; Rats; Rats, Sprague-Dawley; Succinates; Time Factors; Urea; Uremia | 2001 |
Arginine:glycine amidinotransferase deficiency: the third inborn error of creatine metabolism in humans.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Amino Acid Sequence; Base Sequence; Brain; Child; Child, Preschool; Codon, Nonsense; Creatine; Female; Fibroblasts; Genotype; Glycine; Humans; Intellectual Disability; Lymphocytes; Molecular Sequence Data; Nuclear Family; RNA, Messenger | 2001 |
Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenine Nucleotides; Amidinotransferases; Animals; Creatine; Diet; Glycine; Hepatocytes; Homocysteine; Kidney; Liver; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Muscle, Skeletal; Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Sprague-Dawley | 2001 |
Improving treatment of guanidinoacetate methyltransferase deficiency: reduction of guanidinoacetic acid in body fluids by arginine restriction and ornithine supplementation.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Child; Child, Preschool; Creatine; Dietary Supplements; Female; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant; Methyltransferases; Ornithine; Urea | 2001 |
Myocellular creatine and creatine transporter serine phosphorylation after starvation.
Topics: Animals; Creatine; Creatine Kinase; Gene Expression; Glycine; Guanidinoacetate N-Methyltransferase; Male; Membrane Transport Proteins; Methyltransferases; Muscle, Skeletal; Phosphocreatine; Phosphorylation; Rats; Rats, Wistar; RNA, Messenger; Specific Pathogen-Free Organisms; Starvation | 2002 |
Guanidinoacetate and creatine plus creatinine assessment in physiologic fluids: an effective diagnostic tool for the biochemical diagnosis of arginine:glycine amidinotransferase and guanidinoacetate methyltransferase deficiencies.
Topics: Amidinotransferases; Biomarkers; Body Fluids; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatine; Creatinine; Glycine; Guanidinoacetate N-Methyltransferase; Heterozygote; Humans; Male; Methyltransferases; Pedigree | 2002 |
Creatine depletion in a new case with AGAT deficiency: clinical and genetic study in a large pedigree.
Topics: Amidinotransferases; Child, Preschool; Creatine; Female; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Male; Methyltransferases; Pedigree; Psychomotor Disorders | 2002 |
Activation of GABA(A) receptors by guanidinoacetate: a novel pathophysiological mechanism.
Topics: Animals; Animals, Newborn; Binding Sites; Brain; Brain Diseases, Metabolic, Inborn; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; CHO Cells; Creatine; Cricetinae; Female; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Globus Pallidus; Glycine; Guanidinoacetate N-Methyltransferase; Membrane Potentials; Methyltransferases; Mice; Mice, Inbred C57BL; Neurons; Oocytes; Receptors, GABA-A; Receptors, GABA-B; Recombinant Fusion Proteins; Sulfur Radioisotopes; Xenopus | 2002 |
Chronic lithium and sodium valproate both decrease the concentration of myoinositol and increase the concentration of inositol monophosphates in rat brain.
Topics: Animals; Anticonvulsants; Brain Chemistry; Central Nervous System Stimulants; Creatine; Dextroamphetamine; Glucose-6-Phosphate; Glycine; Inositol; Inositol Phosphates; Lithium; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Valproic Acid | 2003 |
Effects of creatine precursors in arthritis; clinical and metabolic study of glycocyamine and betaine.
Topics: Arthritis; Betaine; Creatine; Female; Glycine; Humans | 1952 |
Creatine and guanidoacetic acid metabolism in muscle disease.
Topics: Acetates; Blood; Creatine; Disease; Glycine; Muscles; Muscular Diseases; Urine | 1953 |
Metabolism of creatine and guanidoacetic acid in premature and full-term infants.
Topics: Acetates; Biochemical Phenomena; Creatine; Creatinine; Glycine; Humans; Infant; Infant, Premature | 1953 |
Influence of creatine precursors and high energy phosphates on convalescence from poliomyelitis.
Topics: Acetates; Convalescence; Creatine; Fabaceae; Glycine; Leadership; Phosphates; Poliomyelitis | 1956 |
Relationship between growth and muscle creatine levels in young rats fed supplementary folacin, B12 and methylating agents with and without glycocyamine.
Topics: Animals; Creatine; Folic Acid; Glycine; Growth; Muscles; Musculoskeletal Physiological Phenomena; Physiological Phenomena; Rats | 1956 |
[The use of phosphoglycocyamine in the in vitro biosynthesis of creatine and phosphocreatine].
Topics: Amidines; Coenzymes; Creatine; Glycine; In Vitro Techniques; Liver; Muscles; Musculoskeletal Physiological Phenomena; Phosphocreatine | 1958 |
Effects of dietary creatine and glycine on transamidinase activity in dystrophic mice.
Topics: Amidinotransferases; Animals; Creatine; Creatinine; Diet; Glycine; Kidney; Mice; Muscular Dystrophies; Nutrition Assessment; Transferases | 1961 |
Partial reversal of creatine inhibition of transamidinase by dietary glycine.
Topics: Amidinotransferases; Creatine; Creatinine; Diet; Fabaceae; Glycine; Humans; Transferases | 1961 |
Effect of diet and sex on kidney transamidinase activity in the rat.
Topics: Amidinotransferases; Animals; Creatine; Creatinine; Diet; Fabaceae; Glycine; Kidney; Rats; Sex; Transferases | 1963 |
[RESEARCH ON THE NUTRITION OF ERWINIA CAROTOVORA].
Topics: Alanine; Aminobutyrates; Ammonium Compounds; Arginine; Asparagine; Aspartic Acid; Boron; Calcium; Cobalt; Copper; Creatine; Creatinine; Culture; Culture Media; Cysteine; Cystine; Erwinia; Glutamates; Glycine; Iron; Lysine; Magnesium; Manganese; Methionine; Minerals; Molybdenum; Pectobacterium carotovorum; Proteins; Quaternary Ammonium Compounds; Tryptophan; Tyrosine; Zinc | 1963 |
AN ABNORMALITY OF GLUTAMINE METABOLISM IN PRIMARY GOUT.
Topics: Ammonia; Creatine; Creatinine; Glutamine; Glycine; Gout; Humans; Hyperuricemia; Kidney; Metabolism; Nitrogen; Radioisotopes; Uric Acid; Urine | 1963 |
EXTRACTIVES FROM MUSCLE MEAT OF BALAENOPTERA PHYSALUS (LINNAEUS).
Topics: Alanine; Animals; Cetacea; Chromatography; Creatine; Creatinine; Dipeptides; Fin Whale; Glutamine; Glycine; Guanidines; Histidine; Infrared Rays; Inositol; Meat; Muscles; Picrates; Purines; Research; Taurine; Tissue Extracts | 1963 |
[THE PROBLEM OF THE SPECIFICITY OF GUANIDINE FOR THE DEVELOPMENT OF A GUANIDINE-REQUIRING MUTANT OF POLIOVIRUS].
Topics: Adenine; Amino Acids; Arginine; Creatine; Creatinine; Enterovirus C, Human; Glycine; Guanidine; Guanidines; Hydrazines; Metabolism; Mutation; Ornithine; Poliovirus; Research; Uracil; Urea | 1963 |
TRANSAMIDINASE ACTIVITIES IN VITRO OF KIDNEYS FROM TUMOR-BEARING MICE AND RATS FED DIETS SUPPLEMENTED WITH PROTEIN OR CERTAIN AMINO ACIDS.
Topics: Amidinotransferases; Amino Acids; Animals; Arginine; Blood Chemical Analysis; Carcinoma 256, Walker; Creatine; Creatinine; Diet; Dietary Proteins; Dietary Supplements; Glycine; In Vitro Techniques; Kidney; Mice; Neoplasms; Neoplasms, Experimental; Proteins; Rats; Research; Transferases; Urine | 1964 |
EFFECTS OF DIETARY CREATINE AND RELATED COMPOUNDS ON TISSUE GLYCOGEN DEPOSITION IN RATS.
Topics: Cold Temperature; Creatine; Creatinine; Diet; Glycine; Glycogen; Liver Glycogen; Physiology; Rats; Research; Stress, Physiological; Swimming | 1964 |
[REMARKS ON ISATIN-BETA-THIOSEMICARBAZONE AND ON SEVERAL INHIBITORS OF VIRAL DEVELOPMENT].
Topics: Antiviral Agents; Arginine; Citrulline; Creatine; Creatinine; Enterovirus C, Human; Glutamine; Glycine; Guanidine; Guanidines; Indoles; Isatin; Mutation; Ornithine; Pharmacology; Poliovirus; Thiosemicarbazones; Thiourea; Uracil; Urea | 1964 |
TISSUE REPRESSOR CONCENTRATION AND TARGET ENZYME LEVEL.
Topics: Acetates; Amidines; Citrulline; Creatine; Creatinine; Enzyme Inhibitors; Enzyme Repression; Ethionine; Genetics; Glycine; Guanidine; Guanidines; Liver; Methionine; Ornithine; Pharmacology; Proteins; Research; Transferases | 1964 |
EFFECT OF DIETARY GLYCINE ON TRANSAMIDINASE ACTIVITY OF TUMOR BEARING MICE.
Topics: Amidinotransferases; Animals; Creatine; Creatinine; Diet; Glycine; Humans; Mice; Neoplasms | 1964 |
EVALUATION OF THE AMINO ACID EXCRETION PATTERN OF MENTAL RETARDATES AS A SCREENING TECHNIQUE FOR INBORN ERRORS OF METABOLISM.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Child; Chromatography; Creatine; Creatinine; Cystine; Glutamates; Glutamine; Glycine; Humans; Infant; Intellectual Disability; Mass Screening; Renal Aminoacidurias; Threonine | 1964 |
N15 TRACER STUDIES ON THE ORIGIN OF URINARY AMMONIA IN THE ACIDOTIC DOG, WITH NOTES ON THE ENZYMATIC SYNTHESIS OF LABELED CLUTAMIC ACID AND GLUTAMINES.
Topics: Acidosis; Amino Acids; Ammonia; Blood; Chromatography; Creatine; Creatinine; Dogs; Glutamates; Glutamine; Glycine; Humans; Kidney; Ligases; Nitrogen; p-Aminohippuric Acid; Physiology; Radioisotopes; Research; Urine | 1965 |
Transamidination in the nephrectomized rat.
Topics: Animals; Creatine; Creatinine; Glycine; Nephrectomy; Rats | 1959 |
Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders.
Topics: Adolescent; Adult; Age Factors; Autistic Disorder; Biological Assay; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cohort Studies; Creatine; Creatinine; Developmental Disabilities; Female; Glycine; Humans; Male; Sensitivity and Specificity; Ultraviolet Rays | 2003 |
MR spectroscopy of muscle and brain in guanidinoacetate methyltransferase (GAMT)-deficient mice: validation of an animal model to study creatine deficiency.
Topics: Animals; Brain; Brain Chemistry; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Hindlimb; Humans; Magnetic Resonance Spectroscopy; Metabolism, Inborn Errors; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal | 2003 |
[Metabolism of creatine].
Topics: Creatine; Glycine; Humans | 1950 |
Creatine and glycocyamine metabolism in rabbits in vitamin E deficiency.
Topics: Animals; Creatine; Glycine; Rabbits; Vitamin E; Vitamin E Deficiency | 1951 |
The biochemical basis of betaine-glycocyamine therapy.
Topics: Betaine; Biochemical Phenomena; Cardiovascular Diseases; Creatine; Glycine; Humans | 1951 |
Treatment of cardiac decompensation with betaine and glycocyamine.
Topics: Betaine; Biochemical Phenomena; Cardiovascular Diseases; Creatine; Glycine; Heart Failure; Humans | 1951 |
Use of betaine and glycocyamine in the treatment of patients with heart disease: preliminary report.
Topics: Betaine; Cardiovascular Diseases; Creatine; Glycine; Heart Diseases; Humans | 1951 |
Origin of urinary creatine in progressive muscular dystrophy.
Topics: Creatine; Glycine; Humans; Muscular Dystrophies | 1952 |
Guanidinoacetate methyltransferase deficiency: differences of creatine uptake in human brain and muscle.
Topics: Arginine; Brain; Child; Creatine; Creatinine; Gas Chromatography-Mass Spectrometry; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Magnetic Resonance Spectroscopy; Male; Methyltransferases; Muscle, Skeletal; Ornithine; Phosphocreatine; Turkey | 2004 |
Creatine and guanidinoacetate: diagnostic markers for inborn errors in creatine biosynthesis and transport.
Topics: Adolescent; Adult; Age Factors; Aged; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Female; Gas Chromatography-Mass Spectrometry; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant; Male; Membrane Transport Proteins; Methyltransferases; Reference Values; Syndrome | 2004 |
Guanidinoacetate and creatine/creatinine levels in controls and patients with urea cycle defects.
Topics: Age Factors; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Reference Values; Sensitivity and Specificity; Spain; Urea | 2004 |
Determination of guanidinoacetate and creatine in urine and plasma by liquid chromatography-tandem mass spectrometry.
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Liquid; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Indicator Dilution Techniques; Mass Spectrometry; Methyltransferases; Plasma; Reference Values | 2004 |
Phosphorylated guanidinoacetate partly compensates for the lack of phosphocreatine in skeletal muscle of mice lacking guanidinoacetate methyltransferase.
Topics: Adenosine Triphosphate; Animals; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Homeostasis; Ischemia; Methyltransferases; Mice; Mice, Knockout; Muscle, Skeletal; Phenotype; Phosphocreatine; Phosphorylation; Rest | 2004 |
Age related reference values for urine creatine and guanidinoacetic acid concentration in children and adolescents by gas chromatography-mass spectrometry.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Creatine; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Infant; Infant, Newborn; Male; Reference Values; Sex Factors | 2004 |
Two novel mutations in SLC6A8 cause creatine transporter defect and distinctive X-linked mental retardation in two unrelated Dutch families.
Topics: Base Sequence; Brain; Cells, Cultured; Child; Creatine; DNA; DNA Mutational Analysis; Family Health; Fibroblasts; Glycine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Membrane Transport Proteins; Mental Retardation, X-Linked; Mutation; Netherlands; Skin | 2005 |
In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats.
Topics: Amino Acids; Amygdala; Animals; Creatine; Dipeptides; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Glycine; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Rats; Rats, Wistar; Up-Regulation | 2005 |
Creatine metabolism in combined methylmalonic aciduria and homocystinuria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Female; Glycine; Homocysteine; Homocystinuria; Humans; Male; Methionine; Methylmalonic Acid; Vitamin B 12 | 2005 |
Biochemical and behavioural phenotyping of a mouse model for GAMT deficiency.
Topics: Animals; Behavior, Animal; Brain Chemistry; Creatine; Creatinine; Deficiency Diseases; Disease Models, Animal; Exploratory Behavior; Glycine; Guanidinoacetate N-Methyltransferase; Memory; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Muscles; Neuropsychological Tests; Phenotype; Psychomotor Performance; Reaction Time; Rotarod Performance Test; Spatial Behavior | 2005 |
1H chemical shift imaging of the brain in guanidino methyltransferase deficiency, a creatine deficiency syndrome; guanidinoacetate accumulation in the gray matter.
Topics: Aspartic Acid; Brain Chemistry; Child, Preschool; Choline; Creatine; Glutamic Acid; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Syndrome | 2005 |
Evidence for creatine biosynthesis in Müller glia.
Topics: Amidinotransferases; Animals; Arginine; Cell Line; Creatine; Female; Glutamate-Ammonia Ligase; Glycine; Guanidinoacetate N-Methyltransferase; Male; Methionine; Mice; Neuroglia; Rabbits; Rats; Rats, Wistar; Retina; RNA, Messenger | 2005 |
Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies.
Topics: Adolescent; Betaine; Biomarkers; Child; Child, Preschool; Choline; Creatine; Female; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Methylamines; Muscles; Myositis | 2005 |
Monitoring the effects of chronic alcohol consumption and abstinence on brain metabolism: a longitudinal proton magnetic resonance spectroscopy study.
Topics: Adult; Aged; Alcoholism; Aspartic Acid; Brain Chemistry; Creatine; Female; Functional Laterality; Glycine; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Temperance | 2005 |
Proton magnetic resonance spectroscopy of normal human brain and glioma: a quantitative in vivo study.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Glioma; Glycine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male | 2005 |
1H MR spectroscopy of the brain in Cr transporter defect.
Topics: Brain; Creatine; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Membrane Transport Proteins; Syndrome | 2005 |
Metabolic alterations in focally activated primary somatosensory cortex of alpha-chloralose-anesthetized rats measured by 1H MRS at 11.7 T.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Chloralose; Creatine; Data Interpretation, Statistical; Electric Stimulation; Forelimb; Glutamic Acid; Glycine; Inositol; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Oxygen; Phosphocreatine; Rats; Rats, Sprague-Dawley; Somatosensory Cortex | 2005 |
Phosphagen kinase of the giant tubeworm Riftia pachyptila. Cloning and expression of cytoplasmic and mitochondrial isoforms of taurocyamine kinase.
Topics: Amino Acid Sequence; Animals; Annelida; Arginine; Catalysis; Cloning, Molecular; Creatine; Cytoplasm; DNA, Complementary; Evolution, Molecular; Gene Library; Glycine; Helminths; Kinetics; Mitochondria; Molecular Sequence Data; Phosphotransferases (Nitrogenous Group Acceptor); Phylogeny; Protein Isoforms; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Temperature | 2005 |
Quantitative determination of guanidinoacetate and creatine in dried blood spot by flow injection analysis-electrospray tandem mass spectrometry.
Topics: Amidinotransferases; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant; Infant, Newborn; Nervous System Diseases; Reference Values; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2006 |
Clinicopathological phenotype of ALS with a novel G72C SOD1 gene mutation mimicking a myopathy.
Topics: Aged; Amyotrophic Lateral Sclerosis; Blotting, Western; Creatine; Cysteine; DNA Mutational Analysis; Family Health; Female; Glycine; Humans; Immunohistochemistry; Muscular Diseases; Mutation; Myosins; NAD; Phenotype; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitin | 2006 |
Metabolic phenotyping of nude and normal (Alpk:ApfCD, C57BL10J) mice.
Topics: Alanine; Animals; Biomarkers; Citric Acid; Creatine; Creatinine; Dimethylamines; Female; Glycine; Hippurates; Lactic Acid; Male; Methylamines; Mice; Mice, Inbred C57BL; Mice, Nude; Nuclear Magnetic Resonance, Biomolecular; Phenotype; Principal Component Analysis; Sex Factors; Succinic Acid; Taurine | 2006 |
In vivo localized 1H MR spectroscopy of rat testes: stimulated echo acquisition mode (STEAM) combined with short TI inversion recovery (STIR) improves the detection of metabolite signals.
Topics: Animals; Choline; Creatine; Glutamic Acid; Glycine; Lactates; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Testis | 2006 |
High cerebral guanidinoacetate and variable creatine concentrations in argininosuccinate synthetase and lyase deficiency: implications for treatment?
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Argininosuccinate Synthase; Argininosuccinic Aciduria; Brain; Child; Child, Preschool; Creatine; Female; Glycine; Humans; Infant, Newborn; Male; Pregnancy | 2006 |
Prenatal diagnosis of guanidinoacetate methyltransferase deficiency: increased guanidinoacetate concentrations in amniotic fluid.
Topics: Amniocentesis; Amniotic Fluid; Creatine; Female; Fetal Diseases; Gestational Age; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Pregnancy; Reference Values | 2006 |
Assay for the simultaneous determination of guanidinoacetic acid, creatinine and creatine in plasma and urine by capillary electrophoresis UV-detection.
Topics: Creatine; Creatinine; Electrophoresis, Capillary; Glycine; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2006 |
Methods for the diagnosis of creatine deficiency syndromes: a comparative study.
Topics: Adolescent; Aging; Biomarkers; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatine; Creatinine; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Indicators and Reagents; Infant; Male; Mass Spectrometry; Purine-Pyrimidine Metabolism, Inborn Errors; Reference Standards | 2006 |
GAMT deficiency: features, treatment, and outcome in an inborn error of creatine synthesis.
Topics: Adolescent; Adult; Child; Creatine; Epilepsy; Female; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Male; Metabolism, Inborn Errors; Movement Disorders | 2006 |
Unusual clinical and MRI features of a cerebellopontine angle medulloepithelioma. Case report and review of literature.
Topics: Brain Chemistry; Cerebellar Neoplasms; Cerebellopontine Angle; Child, Preschool; Choline; Creatine; Glycine; Hearing Loss, Bilateral; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neoplasm, Residual; Neuroectodermal Tumors, Primitive | 2006 |
Successful treatment of a guanidinoacetate methyltransferase deficient patient: findings with relevance to treatment strategy and pathophysiology.
Topics: Brain; Child Development; Child, Preschool; Creatine; Dietary Supplements; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Magnetic Resonance Spectroscopy; Treatment Outcome | 2007 |
Acute variations in homocysteine levels are related to creatine changes induced by physical activity.
Topics: Adult; Arginine; Creatine; Exercise Test; Glycine; Homocysteine; Humans; Male; Methionine; Ornithine; Physical Exertion; Physical Fitness | 2007 |
Automated MR spectroscopy of intra- and extraventricular neurocytomas.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Cerebral Ventricle Neoplasms; Cerebral Ventricles; Choline; Contrast Media; Creatine; Female; Gadolinium DTPA; Glycine; Humans; Image Enhancement; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Neurocytoma; Reproducibility of Results | 2007 |
Creatine transporter deficiency: prevalence among patients with mental retardation and pitfalls in metabolite screening.
Topics: Autistic Disorder; Child; Child, Preschool; Creatine; Creatinine; Glycine; Humans; Infant; Intellectual Disability; Male; Mass Screening; Membrane Transport Proteins; Metabolism, Inborn Errors; Reproducibility of Results; Sensitivity and Specificity | 2007 |
Creatine synthesis: production of guanidinoacetate by the rat and human kidney in vivo.
Topics: Adult; Amino Acids; Animals; Citrulline; Creatine; Creatinine; Diet; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Kidney; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Changing the substrate specificity of creatine kinase from creatine to glycocyamine: evidence for a highly evolved active site.
Topics: Amino Acid Sequence; Animals; Binding Sites; Creatine; Creatine Kinase, MM Form; Evolution, Molecular; Gene Expression; Glycine; Humans; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutant Proteins; Phylogeny; Rabbits; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
Reabsorption of creatine and guanidoacetic acid by the renal tubules.
Topics: Creatine; Creatinine; Glycine; Humans; Kidney; Kidney Function Tests; Kidney Tubules; Urine | 1949 |
Urinary glycocyamine, creatine and creatinine; their excretion in children with the nephrotic syndrome.
Topics: Child; Creatine; Creatinine; Glycine; Humans; Infant; Nephritis; Nephrotic Syndrome; Urine | 1949 |
Creatinuria from guanidoacetic acid ingestion and its relation to the site of action of methyltestosterone.
Topics: Creatine; Creatinine; Eating; Glycine; Humans; Methyltestosterone; Urine | 1949 |
Urinary glycocyamine, creatine and creatinine; their excretion by normal infants and children.
Topics: Body Fluids; Child; Creatine; Creatinine; Glycine; Humans; Infant; Urinary Tract; Urine | 1949 |
Arginine and glycine stimulate creatine synthesis in creatine transporter 1-deficient lymphoblasts.
Topics: Arginine; Cell Line; Creatine; Glycine; Guanidines; Humans; Lymphocytes; Membrane Transport Proteins; Propionates | 2008 |
Metabolic markers of neuronal injury correlate with SIV CNS disease severity and inoculum in the macaque model of neuroAIDS.
Topics: AIDS Dementia Complex; Analysis of Variance; Animals; Aspartic Acid; Choline; Creatine; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Inositol; Linear Models; Macaca mulatta; Magnetic Resonance Spectroscopy; Severity of Illness Index; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus | 2008 |
The arginine-creatine pathway is disturbed in children and adolescents with renal transplants.
Topics: Adolescent; Arginine; Cardiovascular Diseases; Case-Control Studies; Child; Creatine; Creatinine; Female; Glycine; Homocysteine; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Methylation; Risk Factors | 2008 |
Quantification of creatine and guanidinoacetate using GC-MS and LC-MS/MS for the detection of cerebral creatine deficiency syndromes.
Topics: Chromatography, High Pressure Liquid; Creatine; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Metabolism, Inborn Errors; Syndrome; Tandem Mass Spectrometry | 2007 |
Cardiac manifestations in a child with a novel mutation in creatine transporter gene SLC6A8.
Topics: Base Sequence; Brain Chemistry; Child; Child Behavior Disorders; Creatine; Developmental Disabilities; Electrocardiography, Ambulatory; Exons; Frameshift Mutation; Glycine; Humans; Language Development Disorders; Magnetic Resonance Spectroscopy; Male; Mental Retardation, X-Linked; Molecular Sequence Data; Nerve Tissue Proteins; Phenotype; Plasma Membrane Neurotransmitter Transport Proteins; Sequence Deletion; Ventricular Premature Complexes | 2008 |
Urinary guanidinoacetate and creatine levels in patients with HPRT deficiency.
Topics: Creatine; Creatinine; Glycine; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome | 2008 |
Simultaneous determination of guanidinoacetate, creatine and creatinine in urine and plasma by un-derivatized liquid chromatography-tandem mass spectrometry.
Topics: Adult; Blood Chemical Analysis; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Chromatography, Liquid; Creatine; Creatinine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Membrane Transport Proteins; Syndrome; Tandem Mass Spectrometry; Young Adult | 2008 |
The effect of testosterone and methyltestosterone on guanidoacetic acid, creatine, and creatinine in plasma and urine.
Topics: Body Fluids; Creatine; Creatinine; Glycine; Methyltestosterone; Plasma; Testosterone | 1948 |
Determination of creatine and guanidinoacetate by GC-MS: study of their stability in urine at different temperatures.
Topics: Acetamides; Creatine; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Organosilicon Compounds; Temperature; Trifluoroacetic Acid | 2009 |
Creatine synthesis: hepatic metabolism of guanidinoacetate and creatine in the rat in vitro and in vivo.
Topics: Amidinotransferases; Animals; Cells, Cultured; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Hepatocytes; Liver; Male; Models, Biological; Nitrogen Isotopes; Rats; Rats, Sprague-Dawley | 2009 |
Low creatinine: the diagnostic clue for a treatable neurologic disorder.
Topics: Biomarkers; Creatine; Creatinine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant; Male; Nervous System Diseases | 2009 |
Guanidinoacetate methyltransferase (GAMT) deficiency diagnosed by proton NMR spectroscopy of body fluids.
Topics: Adult; Body Fluids; Child; Child, Preschool; Creatine; Female; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Hydrogen-Ion Concentration; Infant; Magnetic Resonance Spectroscopy; Male; Protons; Reference Values | 2009 |
MRS is the test of choice for detecting and monitoring disorders of creatine metabolism.
Topics: Brain; Brain Chemistry; Creatine; Developmental Disabilities; Glycine; Humans; Infant; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolic Diseases; Protons; Treatment Outcome | 2009 |
Creatine synthesis is a major metabolic process in neonatal piglets and has important implications for amino acid metabolism and methyl balance.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Animals, Newborn; Arginine; Betaine-Homocysteine S-Methyltransferase; Body Weight; Creatine; Glycine; Homocysteine; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Organ Size; Swine | 2009 |
Simultaneous assay of isotopic enrichment and concentration of guanidinoacetate and creatine by gas chromatography-mass spectrometry.
Topics: Adult; Analytic Sample Preparation Methods; Calibration; Carbon Isotopes; Creatine; Fasting; Fat Emulsions, Intravenous; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Indicator Dilution Techniques; Indicators and Reagents; Infusions, Intravenous; Models, Biological; Nitrogen Isotopes; Pentanones | 2009 |
The blood-brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters.
Topics: Animals; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Models, Biological; Oocytes; Organ Culture Techniques; Rats; Rats, Wistar; RNA, Messenger; Taurine; Xenopus laevis | 2009 |
Dissociation of AGAT, GAMT and SLC6A8 in CNS: relevance to creatine deficiency syndromes.
Topics: Amidinotransferases; Animals; Brain Diseases, Metabolic, Inborn; Brain Mapping; Cell Count; Cells, Cultured; Central Nervous System; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Immunohistochemistry; In Situ Hybridization; Nerve Tissue Proteins; Neurons; Plasma Membrane Neurotransmitter Transport Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Syndrome | 2010 |
Using ex vivo proton magnetic resonance spectroscopy to reveal associations between biochemical and biological features of meningiomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Biomarkers, Tumor; Choline; Creatine; Diagnosis, Differential; Female; Follow-Up Studies; Glutamic Acid; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Prognosis | 2010 |
Diagnosis of creatine metabolism disorders by determining creatine and guanidinoacetate in plasma and urine.
Topics: Amidinotransferases; Chromatography, High Pressure Liquid; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Metabolic Diseases; Tandem Mass Spectrometry | 2010 |
Glycine-creatine metabolism in its relationship to aging.
Topics: Age Factors; Aging; Creatine; Glycine; Humans | 1947 |
Creatine metabolism and the urea cycle.
Topics: Animals; Creatine; Glycine; Humans; Kidney; Urea; Urea Cycle Disorders, Inborn | 2010 |
Is there a role for routinely screening children with autism spectrum disorder for creatine deficiency syndrome?
Topics: Biomarkers; Brain Diseases, Metabolic, Inborn; Child; Child Development Disorders, Pervasive; Chromatography, High Pressure Liquid; Creatine; Female; Glycine; Humans; Male; Mass Screening; Mental Retardation, X-Linked; Plasma Membrane Neurotransmitter Transport Proteins; Syndrome; Tandem Mass Spectrometry | 2010 |
GC/MS determination of guanidinoacetate and creatine in urine: A routine method for creatine deficiency syndrome diagnosis.
Topics: Adolescent; Adult; Brain Diseases, Metabolic, Inborn; Calibration; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatine; Diagnostic Tests, Routine; Female; Gas Chromatography-Mass Spectrometry; Glycine; Humans; Infant; Infant, Newborn; Limit of Detection; Male; Reference Values; Syndrome; Tandem Mass Spectrometry; Young Adult | 2010 |
Creatine prevents the inhibition of energy metabolism and lipid peroxidation in rats subjected to GAA administration.
Topics: Animals; Brain Diseases, Metabolic; Creatine; Disease Models, Animal; Energy Metabolism; Glycine; Guanidinoacetate N-Methyltransferase; Injections, Intraperitoneal; Lipid Peroxidation; Neuroprotective Agents; Oxidative Stress; Rats | 2010 |
Treatment of intractable epilepsy in a female with SLC6A8 deficiency.
Topics: Arginine; Child; Creatine; Drug Therapy, Combination; Epilepsy; Female; Glycine; Heterozygote; Humans; Nerve Tissue Proteins; Plasma Membrane Neurotransmitter Transport Proteins | 2010 |
Disorders of creatine transport and metabolism.
Topics: Amidinotransferases; Brain Diseases, Metabolic, Inborn; Creatine; Creatinine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant, Newborn; Magnetic Resonance Spectroscopy; Mental Retardation, X-Linked; Neonatal Screening; Plasma Membrane Neurotransmitter Transport Proteins | 2011 |
Long-term follow-up and treatment in nine boys with X-linked creatine transporter defect.
Topics: Amino Acid Transport Disorders, Inborn; Arginine; Brain; Child; Child, Preschool; Chromosomes, Human, X; Creatine; Genes, X-Linked; Glycine; Humans; Infant; Intelligence Tests; Magnetic Resonance Spectroscopy; Male; Membrane Transport Proteins; Neurons | 2012 |
Treatment by oral creatine, L-arginine and L-glycine in six severely affected patients with creatine transporter defect.
Topics: Administration, Oral; Adolescent; Amino Acid Transport Disorders, Inborn; Arginine; Child; Child, Preschool; Cognition Disorders; Creatine; Female; Glycine; Humans; Intellectual Disability; Magnetic Resonance Spectroscopy; Male; Membrane Transport Proteins; Nerve Tissue Proteins; Plasma Membrane Neurotransmitter Transport Proteins | 2012 |
Simultaneous determination of creatine and guanidinoacetate in plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Liquid; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant; Infant, Newborn; Middle Aged; Reference Standards; Tandem Mass Spectrometry; Young Adult | 2011 |
Creatine supplementation prevents the accumulation of fat in the livers of rats fed a high-fat diet.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Amidinotransferases; Animals; Carnitine O-Palmitoyltransferase; Creatine; Dietary Fats; Dietary Supplements; Fatty Liver; Gene Expression Regulation; Glycine; Kidney; Lipid Metabolism; Lipid Peroxidation; Liver; Male; PPAR alpha; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Adenosylmethionine | 2011 |
[Amides of creatine: perspectives of neuroprotection].
Topics: Amides; Animals; Brain Ischemia; Creatine; Female; gamma-Aminobutyric Acid; Glycine; Hemodynamics; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Injections, Intravenous; Ischemic Attack, Transient; Male; Microscopy; Microtomy; Models, Animal; Neuroprotective Agents; Phenylalanine; Rats; Rats, Wistar; Tetrazolium Salts; Tyrosine | 2011 |
A simple screening method using ion chromatography for the diagnosis of cerebral creatine deficiency syndromes.
Topics: Brain Diseases, Metabolic, Inborn; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Creatine; Creatinine; Glycine; Humans; Male; Mental Retardation, X-Linked; Plasma Membrane Neurotransmitter Transport Proteins; Transferases | 2012 |
Developmental progress and creatine restoration upon long-term creatine supplementation of a patient with arginine:glycine amidinotransferase deficiency.
Topics: Amidinotransferases; Brain; Child; Creatine; Developmental Disabilities; Dietary Supplements; Female; Glycine; Humans; Mutation | 2012 |
Proton MR spectroscopy of central neurocytoma using short and long echo time: new proofs for the existence of glycine and glutamate.
Topics: Adolescent; Adult; Aspartic Acid; Cerebral Ventricle Neoplasms; Choline; Creatine; Female; Glutamic Acid; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Neurocytoma; Young Adult | 2012 |
Metabonomic responses in rat urine following subacute exposure to propoxur.
Topics: Animals; Carboxylic Acids; Creatine; Glycine; Insecticides; Liver; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabolomics; Propoxur; Rats; Rats, Wistar; Taurine | 2012 |
Guanidinoacetate methyltransferase (GAMT) deficiency in two Tunisian siblings: clinical and biochemical features.
Topics: Abnormalities, Multiple; Adolescent; Amino Acid Metabolism, Inborn Errors; Child; Chromatography, High Pressure Liquid; Consanguinity; Creatine; Female; Genetic Predisposition to Disease; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Lymphocytes; Male; Siblings; Tandem Mass Spectrometry; Tunisia | 2012 |
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutathione; Glycine; Hemangiopericytoma; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Meningeal Neoplasms; Meningioma | 2012 |
Screening for primary creatine deficiencies in French patients with unexplained neurological symptoms.
Topics: Creatine; Creatinine; Female; Glycine; Humans; Male; Nerve Tissue Proteins; Nervous System Diseases; Plasma Membrane Neurotransmitter Transport Proteins; Retrospective Studies | 2012 |
Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.
Topics: Adenylate Kinase; Animals; Creatine; Exercise Tolerance; Female; Glycine; Guanidinoacetate N-Methyltransferase; Heart Failure; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Myocardial Infarction; Oxygen Consumption; Physical Conditioning, Animal; Physical Exertion; Ventricular Remodeling | 2013 |
Creatine and guanidinoacetate content of human milk and infant formulas: implications for creatine deficiency syndromes and amino acid metabolism.
Topics: Adult; Amino Acids; Creatine; Female; Glycine; Humans; Infant; Infant Formula; Infant Nutrition Disorders; Infant Nutritional Physiological Phenomena; Milk, Human | 2013 |
Arginine-guanidinoacetate-creatine pathway in preterm newborns: creatine biosynthesis in newborns.
Topics: Arginine; Birth Weight; Case-Control Studies; Creatine; Female; Gestational Age; Glycine; Humans; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Male; Metabolic Networks and Pathways; Models, Biological | 2013 |
Elevation of guanidinoacetate in newborn dried blood spots and impact of early treatment in GAMT deficiency.
Topics: Case-Control Studies; Child, Preschool; Creatine; Dried Blood Spot Testing; Early Diagnosis; Female; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant; Infant, Newborn; Language Development Disorders; Male; Movement Disorders; Ornithine; Treatment Outcome | 2013 |
Partitioning of [methyl-3H]methionine to methylated products and protein is altered during high methyl demand conditions in young Yucatan miniature pigs.
Topics: Animals; Animals, Newborn; Creatine; DNA Methylation; Fetal Growth Retardation; Glycine; Methionine; Methylation; Phosphatidylcholines; Proteins; Swine; Swine, Miniature; Tritium | 2013 |
Dietary glycine+serine responses of male broilers given low-protein diets with different concentrations of threonine.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Creatine; Diet; Diet, Protein-Restricted; Dietary Proteins; Dietary Supplements; Digestion; Dose-Response Relationship, Drug; Glycine; Male; Pectoralis Muscles; Serine; Threonine; Uric Acid | 2013 |
Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Brain; Child; Creatine; Developmental Disabilities; Female; Glycine; Humans; Intellectual Disability; Magnetic Resonance Spectroscopy; Speech Disorders | 2013 |
Urinary metabolomics in newborns infected by human cytomegalovirus: a preliminary investigation.
Topics: 3-Hydroxybutyric Acid; Adult; Aminoisobutyric Acids; Betaine; Creatine; Cytomegalovirus; Cytomegalovirus Infections; Discriminant Analysis; Female; Glycine; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Inositol; Magnetic Resonance Spectroscopy; Metabolomics; Pregnancy; Pregnancy Complications, Infectious; Taurine | 2013 |
Creatine and guanidinoacetate reference values in a French population.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amino Acid Metabolism, Inborn Errors; Case-Control Studies; Child; Child, Preschool; Creatine; Female; France; Glycine; Humans; Infant; Infant, Newborn; Male; Middle Aged; Reference Values; Sex Factors; White People; Young Adult | 2013 |
Synthesis of guanidinoacetate and creatine from amino acids by rat pancreas.
Topics: Amidinotransferases; Amino Acids; Animals; Creatine; Creatinine; Diet; Dietary Supplements; Glycine; Guanidinoacetate N-Methyltransferase; Kidney; Liver; Male; Pancreas; Phosphocreatine; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2014 |
Alcohol consumption decreases rat hepatic creatine biosynthesis via altered guanidinoacetate methyltransferase activity.
Topics: Alcohol Drinking; Animals; Antimetabolites, Antineoplastic; Apoptosis; Central Nervous System Depressants; Creatine; Ethanol; Glycine; Guanidinoacetate N-Methyltransferase; Hepatocytes; Kidney; Liver; Male; Myocardium; Rats; Rats, Wistar; S-Adenosylhomocysteine; Tubercidin | 2014 |
Guanidinoacetate methyltransferase (GAMT) deficiency: outcomes in 48 individuals and recommendations for diagnosis, treatment and monitoring.
Topics: Adolescent; Adult; Arginine; Brain; Child; Child, Preschool; Combined Modality Therapy; Creatine; Female; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant; Infant, Newborn; Intellectual Disability; Language Development Disorders; Male; Middle Aged; Movement Disorders; Ornithine; Practice Guidelines as Topic; Sodium Benzoate; Treatment Outcome; Young Adult | 2014 |
GAMT deficiency: 20 years of a treatable inborn error of metabolism.
Topics: Arginine; Creatine; Female; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Intellectual Disability; Language Development Disorders; Male; Movement Disorders; Ornithine; Sodium Benzoate | 2014 |
Feasibility of newborn screening for guanidinoacetate methyltransferase (GAMT) deficiency.
Topics: Brain; Creatine; Dried Blood Spot Testing; False Positive Reactions; Feasibility Studies; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant, Newborn; Language Development Disorders; Movement Disorders; Neonatal Screening; Retrospective Studies | 2014 |
Diagnosis and therapeutic monitoring of inborn errors of creatine metabolism and transport using liquid chromatography-tandem mass spectrometry in urine, plasma and CSF.
Topics: Case-Control Studies; Child; Creatine; Creatinine; Female; Gas Chromatography-Mass Spectrometry; Genetic Diseases, Inborn; Glycine; Humans; Infant; Male; Reference Standards; Young Adult | 2014 |
Newborn screening for guanidinoacetate methyl transferase deficiency.
Topics: Arginine; Creatine; Diet; Female; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Intellectual Disability; Language Development Disorders; Male; Metabolism, Inborn Errors; Movement Disorders; Ornithine; Sodium Benzoate | 2014 |
Neurochemical alterations in frontal cortex of the rat after one week of hypobaric hypoxia.
Topics: Alanine; Altitude; Animals; Corpus Striatum; Creatine; Depressive Disorder; Female; Frontal Lobe; Glutamic Acid; Glycine; Hippocampus; Hypoxia; Inositol; Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley; Swimming; Time Factors | 2014 |
Decreased cerebrospinal fluid levels of L-carnitine in non-apolipoprotein E4 carriers at early stages of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Arginine; Biomarkers; Carnitine; Cognition Disorders; Cognitive Dysfunction; Creatine; Dicarboxylic Acids; Female; Glycine; Heterozygote; Humans; Male; Middle Aged; Neuropsychological Tests; Peptide Fragments; Sensitivity and Specificity; tau Proteins | 2014 |
Urine NMR metabolomics analysis of breastfeeding biomarkers during and after pregnancy in a large prospective cohort study.
Topics: Adaptation, Physiological; Adult; Biomarkers; Breast Feeding; Creatine; Creatinine; Female; Gestational Age; Glycine; Humans; Infant; Infant Formula; Infant, Newborn; Lactose; Metabolomics; Norway; Pregnancy; Prospective Studies; Time Factors | 2014 |
Treatment of arginase deficiency revisited: guanidinoacetate as a therapeutic target and biomarker for therapeutic monitoring.
Topics: Benzoates; Biomarkers; Child; Creatine; Glycine; Humans; Hyperargininemia; Male; Ornithine; Treatment Outcome | 2014 |
High-throughput tandem mass spectrometry multiplex analysis for newborn urinary screening of creatine synthesis and transport disorders, Triple H syndrome and OTC deficiency.
Topics: Biomarkers; Creatine; Creatinine; Filtration; Glycine; Humans; Hyperammonemia; Infant, Newborn; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Paper; Reference Values; Reproducibility of Results; Tandem Mass Spectrometry; Uracil; Urea Cycle Disorders, Inborn; Urinalysis | 2014 |
Mild guanidinoacetate increase under partial guanidinoacetate methyltransferase deficiency strongly affects brain cell development.
Topics: Animals; Apoptosis; Axons; Brain; Cells, Cultured; Coculture Techniques; Creatine; Dependovirus; Genetic Vectors; Glycine; Guanidinoacetate N-Methyltransferase; Neuroglia; Neurons; Rats, Sprague-Dawley; Receptors, GABA-A; RNA Interference | 2015 |
Guanidinoacetate is more effective than creatine at enhancing tissue creatine stores while consequently limiting methionine availability in Yucatan miniature pigs.
Topics: Animals; Body Weight; Creatine; Diet; Dietary Supplements; Glycine; Liver; Methionine; Methylation; Muscles; S-Adenosylmethionine; Swine; Swine, Miniature; Tissue Distribution | 2015 |
Treatment of Creatine Transporter (SLC6A8) Deficiency With Oral S-Adenosyl Methionine as Adjunct to L-arginine, Glycine, and Creatine Supplements.
Topics: Administration, Oral; Arginine; Basal Ganglia; Brain Diseases, Metabolic, Inborn; Central Nervous System Agents; Child; Creatine; Drug Therapy, Combination; Follow-Up Studies; Glycine; Humans; Magnetic Resonance Spectroscopy; Male; Medication Adherence; Mental Retardation, X-Linked; Plasma Membrane Neurotransmitter Transport Proteins; S-Adenosylmethionine; Treatment Outcome | 2015 |
Accurate grading of brain gliomas by soft independent modeling of class analogy based on non-negative matrix factorization of proton magnetic resonance spectra.
Topics: Algorithms; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glycine; Humans; Neoplasm Grading; Principal Component Analysis; Proton Magnetic Resonance Spectroscopy | 2016 |
Low visual cortex GABA levels in hepatic encephalopathy: links to blood ammonia, critical flicker frequency, and brain osmolytes.
Topics: Ammonia; Brain Chemistry; Creatine; Female; Flicker Fusion; gamma-Aminobutyric Acid; Glutamine; Glycine; Hepatic Encephalopathy; Humans; Inositol; Male; Middle Aged; Neuropsychological Tests; Osmolar Concentration; Visual Cortex | 2015 |
Arginine:glycine amidinotransferase (AGAT) deficiency: Clinical features and long term outcomes in 16 patients diagnosed worldwide.
Topics: Adolescent; Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Developmental Disabilities; Female; Gene Expression; Genes, Recessive; Glycine; Humans; Intellectual Disability; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Muscular Diseases; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Analysis, DNA; Speech Disorders; Treatment Outcome; Young Adult | 2015 |
Digestibility and metabolism of dietary guanidino acetic acid fed to broilers.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Creatine; Diet; Dietary Supplements; Digestion; Feces; Glycine; Male | 2016 |
Guanidinoacetic acid increases skeletal muscle creatine stores in healthy men.
Topics: Adult; Creatine; Glycine; Humans; Male; Muscle, Skeletal; Pilot Projects; Reference Values | 2016 |
Creatine metabolism: detection of creatine and guanidinoacetate in saliva of healthy subjects.
Topics: Adolescent; Adult; Child; Child, Preschool; Creatine; Female; Glycine; Humans; Male; Middle Aged; Reference Values; Saliva; Young Adult | 2016 |
A new perspective to improve brain bioenergetics in disorders with functional GAMT and CT1.
Topics: Animals; Brain; Brain Diseases, Metabolic; Creatine; Energy Metabolism; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Membrane Transport Proteins | 2016 |
NMR Metabolomics Investigates the Influence of Flavonoid-Enriched Rations on Chicken Plasma.
Topics: 3-Hydroxybutyric Acid; Acetic Acid; Alanine; Animal Feed; Animals; Anti-Inflammatory Agents; Antioxidants; Betaine; Chickens; Citric Acid; Creatine; Dietary Supplements; Flavanones; Glycine; Hesperidin; Lipoproteins; Metabolomics; Poultry; Succinic Acid; Vitamin E | 2017 |
Does maternal-fetal transfer of creatine occur in pregnant sheep?
Topics: Animals; Creatine; Female; Glycine; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy, Animal; Sheep | 2017 |
Co-administration of creatine and guanidinoacetic acid for augmented tissue bioenergetics: A novel approach?
Topics: Creatine; Energy Metabolism; Glycine; Models, Biological; Organ Specificity | 2017 |
Creatine supplementation to total parenteral nutrition improves creatine status and supports greater liver and kidney protein synthesis in neonatal piglets.
Topics: Animals; Animals, Newborn; Arginine; Body Weight; Cholesterol; Creatine; Dietary Supplements; Glycine; Kidney; Lipids; Liver; Muscle, Skeletal; Organ Size; Parenteral Nutrition; Random Allocation; Swine; Swine, Miniature; Triglycerides | 2018 |
Cell-Type-Specific Spatiotemporal Expression of Creatine Biosynthetic Enzyme S-adenosylmethionine:guanidinoacetate N-methyltransferase in Developing Mouse Brain.
Topics: Animals; Brain; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Methyltransferases; Mice, Inbred C57BL; Neurons; Phosphocreatine; S-Adenosylmethionine | 2018 |
Guanidinoacetic Acid and Creatine are Associated with Cardiometabolic Risk Factors in Healthy Men and Women: A Cross-Sectional Study.
Topics: Adolescent; Adult; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Chromatography, Liquid; Cohort Studies; Creatine; Cross-Sectional Studies; Female; Glycine; Humans; Insulin; Insulin Secretion; Male; Metabolic Diseases; Middle Aged; Overweight; Risk Factors; Tandem Mass Spectrometry; Triglycerides; Young Adult | 2018 |
Creatine Transporter Deficiency in Two Brothers with Autism Spectrum Disorder.
Topics: Adolescent; Arginine; Autism Spectrum Disorder; Brain Diseases, Metabolic, Inborn; Child; Creatine; Glycine; Humans; Male; Mental Retardation, X-Linked; Nerve Tissue Proteins; Plasma Membrane Neurotransmitter Transport Proteins; S-Adenosylmethionine; Siblings | 2018 |
Serum creatine is not a reliable marker of muscular fitness in young adults.
Topics: Adult; Creatine; Creatinine; Cross-Sectional Studies; Female; Glycine; Hand Strength; Humans; Male; Young Adult | 2018 |
Treatment outcome of creatine transporter deficiency: international retrospective cohort study.
Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Creatine; Creatinine; Female; Genotype; Glycine; Humans; Infant; Intellectual Disability; Male; Membrane Transport Proteins; Phenotype; Seizures; Treatment Outcome; Young Adult | 2018 |
Effects of guanidinoacetic acid on growth performance, creatine and energy metabolism, and carcass characteristics in growing-finishing pigs.
Topics: Animal Feed; Animals; Creatine; Diet; Dietary Supplements; Energy Metabolism; Female; Glycine; Glycine max; Liver; Male; Swine; Zea mays | 2018 |
Hydrophilic interaction chromatography coupled to tandem mass spectrometry as a method for simultaneous determination of guanidinoacetate and creatine.
Topics: Calibration; Chromatography, Liquid; Creatine; Glycine; Humans; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Reproducibility of Results; Tandem Mass Spectrometry; Time Factors | 2018 |
Creatine Monohydrate and Guanidinoacetic Acid Supplementation Affects the Growth Performance, Meat Quality, and Creatine Metabolism of Finishing Pigs.
Topics: Animal Feed; Animals; Calpain; Creatine; Dietary Supplements; Glycine; Kidney; Liver; Meat; Muscles; Swine | 2018 |
Attenuating effects of guanidinoacetic acid on preslaughter transport-induced muscle energy expenditure and rapid glycolysis of broilers.
Topics: Animal Feed; Animals; Blood Glucose; Chickens; Corticosterone; Creatine; Diet; Energy Metabolism; Glycine; Glycolysis; Male; Meat; Pectoralis Muscles; Random Allocation; Stress, Physiological; Transportation | 2019 |
Guanidinoacetic acid is efficacious in improving growth performance and muscle energy homeostasis in broiler chicks fed arginine-deficient or arginine-adequate diets.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Creatine; Diet; Energy Metabolism; Glycine; Homeostasis; Male; Muscles | 2019 |
LC-MS/MS measurements of urinary guanidinoacetic acid and creatine: Method optimization by deleting derivatization step.
Topics: Chromatography, High Pressure Liquid; Clinical Laboratory Techniques; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Language Development Disorders; Movement Disorders; Tandem Mass Spectrometry | 2019 |
Stability of creatine monohydrate and guanidinoacetic acid during manufacture (retorting and extrusion) and storage of dog foods.
Topics: Animal Feed; Animals; Creatine; Dogs; Food Preservation; Food Storage; Glycine; Time Factors | 2019 |
The Kidneys Are Quantitatively More Important than Pancreas and Gut as a Source of Guanidinoacetic Acid for Hepatic Creatine Synthesis in Sow-Reared Yucatan Miniature Piglets.
Topics: Amino Acids; Animals; Creatine; Female; Glycine; Intestinal Mucosa; Kidney; Liver; Methylation; Pancreas; Swine; Swine, Miniature | 2020 |
Effects of supplemental creatine and guanidinoacetic acid on spatial memory and the brain of weaned Yucatan miniature pigs.
Topics: Animal Feed; Animals; Brain; Creatine; Diet; Dietary Supplements; Glycine; Male; Spatial Memory; Swine; Swine, Miniature; Weaning | 2020 |
Magnetic resonance imaging reveals specific anatomical changes in the brain of Agat- and Gamt-mice attributed to creatine depletion and guanidinoacetate alteration.
Topics: Animals; Arginine; Brain; Chromatography, High Pressure Liquid; Creatine; DNA Modification Methylases; DNA Repair Enzymes; Glycine; Guanidinoacetate N-Methyltransferase; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Phenotype; Tumor Suppressor Proteins | 2020 |
Effect of post-ruminal guanidinoacetic acid supplementation on creatine synthesis and plasma homocysteine concentrations in cattle.
Topics: Abomasum; Animal Feed; Animals; Arginine; Cattle; Creatine; Diet; Dietary Supplements; Female; Glycine; Homocysteine; Medicago sativa; Methionine; Random Allocation; Zea mays | 2020 |
Presence of guanidinoacetate may compensate creatine absence and account for less statin-induced muscle damage in GAMT-deficient compared to AGAT-deficient mice.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Creatine; Developmental Disabilities; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intellectual Disability; Language Development Disorders; Mice; Movement Disorders; Muscular Diseases; Phosphorylation; Speech Disorders | 2020 |
Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Brain; Carnitine; Creatine; Creatinine; Developmental Disabilities; gamma-Aminobutyric Acid; Glycine; Humans; Male; Metabolomics; Succinate-Semialdehyde Dehydrogenase | 2020 |
Homoarginine- and Creatine-Dependent Gene Regulation in Murine Brains with l-Arginine:Glycine Amidinotransferase Deficiency.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Arginine; Brain; Creatine; Developmental Disabilities; Gene Expression Regulation; Glycine; Homoarginine; Intellectual Disability; Mice; Mice, Inbred C57BL; Speech Disorders; Stroke | 2020 |
Human gut microbiota as a source of guanidinoacetic acid.
Topics: Amino Acids; Creatine; Dietary Supplements; Gastrointestinal Microbiome; Glycine; Humans | 2020 |
Creatine, guanidinoacetate and homoarginine in statin-induced myopathy.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Creatine; Developmental Disabilities; Glycine; Guanidinoacetate N-Methyltransferase; Homoarginine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intellectual Disability; Mice; Muscular Diseases; Phosphocreatine; Speech Disorders | 2020 |
From broiler breeder hen feed to the egg and embryo: The molecular effects of guanidinoacetate supplementation on creatine transport and synthesis.
Topics: Animal Feed; Animals; Biological Transport; Chickens; Creatine; Diet; Dietary Supplements; Female; Gene Expression; Glycine; Ovum; Random Allocation | 2020 |
Relative bioavailability of guanidinoacetic acid delivered ruminally or abomasally to cattle.
Topics: Abomasum; Animals; Biological Availability; Cattle; Creatine; Glycine; Rumen | 2020 |
Guanidinoacetic acid supplementation improves feed conversion in broilers subjected to heat stress associated with muscle creatine loading and arginine sparing.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Creatine; Diet; Dietary Supplements; Energy Metabolism; Glycine; Heat-Shock Response; Male | 2020 |
Effects of guanidinoacetic acid and coated folic acid supplementation on growth performance, nutrient digestion and hepatic gene expression in Angus bulls.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cattle; Creatine; Detergents; Diet; Dietary Supplements; Digestion; Folic Acid; Gene Expression; Glycine; Insulin-Like Growth Factor I; Liver; Male; Nutrients; Phosphatidylinositol 3-Kinases; Rumen | 2021 |
Cross-sectional analysis of plasma and CSF metabolomic markers in Huntington's disease for participants of varying functional disability: a pilot study.
Topics: Adult; Arginine; Biomarkers; Creatine; Cross-Sectional Studies; Disability Evaluation; Female; Glycine; Humans; Huntington Disease; Male; Metabolomics; Middle Aged; Pilot Projects; Treatment Outcome; Young Adult | 2020 |
Neurometabolite mapping highlights elevated myo-inositol profiles within the developing brain in down syndrome.
Topics: Aspartic Acid; Brain; Choline; Creatine; Down Syndrome; Female; Fetus; Glycine; Humans; Infant, Newborn; Inositol; Magnetic Resonance Spectroscopy; Male | 2021 |
Creatine improves the flesh quality of Pacific white shrimp (Litopenaeus vannamei) reared in freshwater.
Topics: Amino Acids; Animals; Collagen; Creatine; Dietary Supplements; Down-Regulation; Fresh Water; Glycine; Hepatopancreas; Muscle Proteins; Muscles; Myosin Heavy Chains; Penaeidae; RNA, Messenger; Up-Regulation | 2021 |
Effect of guanidinoacetic acid supplementation in cattle.
Topics: Animal Feed; Animals; Cattle; Creatine; Diet; Dietary Supplements; Glycine | 2021 |
Effect of Creatine and Guanidinoacetate Supplementation on Plasma Homocysteine in Metabolically Healthy Men and Women.
Topics: Creatine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Male | 2021 |
Guanidinoacetate-creatine in secondary progressive multiple sclerosis: a case report.
Topics: Creatine; Female; Glycine; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive | 2022 |
Guanidinoacetic acid as a partial replacement to arginine with or without betaine in broilers offered moderately low crude protein diets.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Chickens; Creatine; Diet; Diet, Protein-Restricted; Dietary Supplements; Glycine; Male; Weight Gain | 2022 |
Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF.
Topics: Animals; Choroid Plexus; Creatine; Epithelial Cells; Glycine; Guanidinoacetate N-Methyltransferase; Rats | 2022 |
Laboratory Diagnosis of Cerebral Creatine Deficiency Syndromes by Determining Creatine and Guanidinoacetate in Plasma and Urine.
Topics: Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant, Newborn; Neonatal Screening; Syndrome; Tandem Mass Spectrometry | 2022 |
Does Methionine Status Influence the Outcome of Selenomethinione Supplementation? A Comparative Study of Metabolic and Selenium Levels in HepG2 Cells.
Topics: Amino Acids; Aspartic Acid; Choline; Citrates; Creatine; Dietary Supplements; Glycine; Hep G2 Cells; Humans; Hypoxanthines; Lactates; Methionine; Nucleoside Diphosphate Sugars; Racemethionine; Selenium; Selenomethionine; Selenoproteins | 2022 |