colistin has been researched along with indole* in 1 studies
1 other study(ies) available for colistin and indole
Article | Year |
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Indole and (E)-2-hexenal, phytochemical potentiators of polymyxins against Pseudomonas aeruginosa and Escherichia coli.
Combinations of polymyxins and phytochemicals were tested for antimicrobial activity against two gram-negative bacteria. Various degrees of potentiation were found against Pseudomonas aeruginosa and Escherichia coli with (E)-2-hexenal and indole. Three-compound combinations were found to further increase the activity of polymyxin B sulfate and colistin methanesulfonate against both bacteria. Combinations with colistin against P. aeruginosa resulted in the highest degree of potentiation, with a 512-fold increase in colistin antimicrobial activity. These results indicate the potential efficacy of phytochemical combinations with antibiotics to enhance total biological activity. Topics: Anti-Bacterial Agents; Colistin; Drug Combinations; Drug Synergism; Escherichia coli; GABA Modulators; Hexobarbital; Indoles; Microbial Sensitivity Tests; Polymyxin B; Pseudomonas aeruginosa | 1996 |