Page last updated: 2024-08-17

colchicine and digoxin

colchicine has been researched along with digoxin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's5 (19.23)18.2507
2000's8 (30.77)29.6817
2010's12 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A1
Thakker, DR; Troutman, MD1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
de Lannoy, IA; Silverman, M1
Cano, NJ; Carcagne, J; Grandgeorge, M; Sabouraud, AE; Scherrmann, JM; Urtizberea, M1
Smith, GH1
Benmoussa, K; Cano, NJ; Mani, JC; Navarro-Teulon, I; Roquet, F; Sabouraud, AE; Scherrmann, JM1
Scherrmann, JM1
Baud, FJ; Bismuth, C; Borron, SW; Scherrmann, JM; Taboulet, P1
Almeida, I; Ely, D; Podila, L; Taub, ME1
Audus, K; Galinis, D; Mitra, P; Williams, G; Yazdanian, M1
Cai, YD; Chen, L; Huang, T; Kong, X; Yang, J; Zheng, M1

Reviews

2 review(s) available for colchicine and digoxin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antibody treatment of toxin poisoning--recent advances.
    Journal of toxicology. Clinical toxicology, 1994, Volume: 32, Issue:4

    Topics: Animals; Binding Sites; Colchicine; Digoxin; Humans; Immunotherapy; Tissue Distribution; Toxins, Biological; Venoms

1994

Other Studies

24 other study(ies) available for colchicine and digoxin

ArticleYear
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
    Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine

2003
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
    Pharmaceutical research, 2003, Volume: 20, Issue:8

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics

2003
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin.
    Biochemical and biophysical research communications, 1992, Nov-30, Volume: 189, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; CHO Cells; Colchicine; Cricetinae; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Resistance; Kinetics; Membrane Glycoproteins; Quinidine; Verapamil; Vinblastine

1992
Analytical control procedures of immunoreactivity for IgG and Fab fragments specific to haptens.
    Pharmaceutical research, 1992, Volume: 9, Issue:5

    Topics: Antibody Specificity; Binding Sites, Antibody; Colchicine; Digitoxin; Digoxin; Haptens; Immunoglobulin Fab Fragments; Immunoglobulin Fragments

1992
Case studies of a clinical pharmacist.
    American journal of hospital pharmacy, 1972, Volume: 29, Issue:11

    Topics: Aged; Alcoholism; Allopurinol; Arrhythmias, Cardiac; Chloral Hydrate; Colchicine; Digoxin; Drug Synergism; Gastrointestinal Hemorrhage; Gout; Hospitals, Teaching; Humans; Liver Diseases; Male; Middle Aged; Nitroglycerin; Patient Care Team; Pharmacists; Pharmacy Service, Hospital; Quinidine; Warfarin; Washington

1972
Monoclonal digoxin-specific antibodies induce dose- and affinity-dependent plasma digoxin redistribution in rats.
    Pharmaceutical research, 1995, Volume: 12, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Colchicine; Digoxin; Dose-Response Relationship, Drug; Immunoglobulin G; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tritium

1995
Immunotoxicotherapy: successes, disappointments and hopes.
    Human & experimental toxicology, 1997, Volume: 16, Issue:10

    Topics: Adult; Antibodies, Monoclonal; Antidepressive Agents, Tricyclic; Antivenins; Arrhythmias, Cardiac; Binding Sites, Antibody; Colchicine; Digoxin; Female; Humans; Immunization, Passive; Immunoglobulin Fab Fragments; Immunotherapy; Lipopolysaccharides; Poisoning; Sepsis; Venoms

1997
Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:11

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Caco-2 Cells; Cell Line; Cell Membrane Permeability; Cell Polarity; Colchicine; Dexamethasone; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Humans; Hydrocortisone; Paclitaxel; Probenecid; Time Factors; Transfection; Vinblastine

2005
A comprehensive study demonstrating that p-glycoprotein function is directly affected by changes in pH: implications for intestinal pH and effects on drug absorption.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:10

    Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Biological Transport; Caco-2 Cells; Colchicine; Digoxin; Dogs; Humans; Hydrogen-Ion Concentration; Hydrolysis; Intestinal Absorption; Intestinal Mucosa; Madin Darby Canine Kidney Cells; Permeability; Protein Conformation; Structure-Activity Relationship; Transfection

2011
The Use of Chemical-Chemical Interaction and Chemical Structure to Identify New Candidate Chemicals Related to Lung Cancer.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Animals; Antineoplastic Agents; Arsenicals; Berberine; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Colchicine; Daunorubicin; Digoxin; Drug Discovery; Humans; Lung; Lung Neoplasms; Ouabain; Prednisone; Small Cell Lung Carcinoma; Tretinoin

2015
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