clonidine and mk 912
clonidine has been researched along with mk 912 in 12 studies
Research
Studies (12)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bamford, O; Hawkins, RL | 1 |
| Dollery, CT; Fuller, RW; Gertz, BJ; Warren, JB; Williams, VC | 1 |
| Baldwin, JJ; Clineschmidt, BV; Huff, JR; Lotti, VJ; Pettibone, DJ; Randall, WC; Vacca, J; Young, SD | 1 |
| Clineschmidt, BV; Hucker, HB; Huff, JR; Lis, EV; Lotti, VJ; Pettibone, DJ; Reiss, DR; Sweeney, BM; Vacca, J | 1 |
| Muceniece, R; Rangel, N; Tiger, G; Uhlén, S; Wikberg, JE | 1 |
| Bouloumié, A; Devedjian, JC; Lafontan, M; Planat, V; Record, M; Saulnier-Blache, JS; Valet, P | 1 |
| Dan, K; Hirose, H; Maruyama, H; Nakamura, K; Saruta, T; Seto, Y | 1 |
| Blue, DR; Dillon, MP; Eglen, RM; Jasper, JR; Lesnick, JD; MacLennan, SJ; Zhu, QM | 1 |
| Centurión, D; Gupta, S; Jiménez-Mena, LR; Lozano-Cuenca, J; MaassenVanDenBrink, A; Mehrotra, S; Muñoz-Islas, E; Sánchez-López, A; Villalón, CM | 1 |
| Centurión, D; Görnemann, T; Jähnichen, S; Kleuser, B; Pertz, HH; Villalón, CM; von Wenckstern, H | 1 |
| Honda, M; Ishikawa, T; Nakayama, K; Suzuki, M | 1 |
| Albarrán-Juárez, JA; Centurión, D; Görnemann, T; Lozano-Cuenca, J; Pertz, HH; Villalón, CM | 1 |
Trials
1 trial(s) available for clonidine and mk 912
| Article | Year |
|---|---|
Assessment of MK-912, an alpha 2-adrenoceptor antagonist, with use of intravenous clonidine.
Topics: Adrenergic alpha-Antagonists; Adult; Blood Glucose; Blood Pressure; Clonidine; Double-Blind Method; Gonadotropins; Heart Rate; Humans; Infusions, Intravenous; Male; Quinolizines; Random Allocation; Salivation | 1989 |
Other Studies
11 other study(ies) available for clonidine and mk 912
| Article | Year |
|---|---|
Central effects of an alpha 2-adrenergic antagonist on fetal lambs: a possible mechanism for hypoxic apnea.
Topics: Adrenergic alpha-Antagonists; Animals; Apnea; Clonidine; Female; Fetal Diseases; Fetal Hypoxia; Pregnancy; Quinolizines; Receptors, Adrenergic, alpha; Respiration; Sheep | 1990 |
Pharmacological profile of a new potent and specific alpha 2-adrenoceptor antagonist, L-657,743.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Binding, Competitive; Blood Platelets; Cattle; Cerebral Cortex; Clonidine; Humans; In Vitro Techniques; Ketanserin; Male; Prazosin; Quinolizines; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Vas Deferens | 1987 |
A peripherally acting alpha-2 adrenoceptor antagonist: L-659,066.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood-Brain Barrier; Callitrichinae; Clonidine; Decerebrate State; Dihydroxyphenylalanine; Gastrointestinal Motility; Male; Muscle Contraction; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1988 |
Comparison of the binding activities of some drugs on alpha 2A, alpha 2B and alpha 2C-adrenoceptors and non-adrenergic imidazoline sites in the guinea pig.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Cerebral Cortex; Clonidine; Guinea Pigs; Imidazoles; Imidazoline Receptors; Kidney; Quinolizines; Rats; Receptors, Adrenergic, alpha-2; Receptors, Drug | 1995 |
Alpha 2-adrenergic stimulation promotes preadipocyte proliferation. Involvement of mitogen-activated protein kinases.
Topics: 3T3 Cells; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Clone Cells; Clonidine; Cyclic AMP; Dioxanes; Humans; Idazoxan; Kinetics; Male; Mice; Pertussis Toxin; Quinolizines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1994 |
Effects of alpha 2-adrenergic agonism, imidazolines, and G-protein on insulin secretion in beta cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Glucose; GTP-Binding Proteins; Humans; Imidazoles; Indoles; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Molecular Structure; Oxymetazoline; Pancreatic Neoplasms; Pertussis Toxin; Phentolamine; Pyrroles; Quinolizines; Receptors, Adrenergic, alpha-2; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1997 |
Cardiovascular effects of rilmenidine, moxonidine and clonidine in conscious wild-type and D79N alpha2A-adrenoceptor transgenic mice.
Topics: Adrenergic alpha-Antagonists; Amino Acid Substitution; Animals; Binding, Competitive; Blood Pressure; Cardiovascular Agents; Cell Line; Clonidine; Consciousness; Dogs; Heart Rate; Humans; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Mutation; Naphthyridines; Oxazoles; Quinolizines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Rilmenidine; Saphenous Vein; Tritium | 1999 |
Clonidine inhibits the canine external carotid vasodilatation to capsaicin by alpha2A/2C-adrenoceptors.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Carotid Artery, External; Clonidine; Dogs; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Indoles; Isoindoles; Male; Phenylephrine; Quinolizines; Receptors, Adrenergic, alpha-2; Reproducibility of Results; Vasodilation; Yohimbine | 2006 |
Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Gene Expression; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Neuromuscular Junction; Norepinephrine; Piperazines; Prazosin; Pulmonary Veins; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Vasoconstriction; Yohimbine | 2007 |
Role of alpha2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenalectomy; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amides; Anesthetics, Local; Animals; Blood Pressure; Blood Vessels; Body Temperature Regulation; Clonidine; Cold Temperature; Heart Rate; Intracellular Signaling Peptides and Proteins; Isoquinolines; Laser-Doppler Flowmetry; Male; Mice; Naphthyridines; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Quinolizines; Receptors, Adrenergic, alpha-2; Reflex; Regional Blood Flow; rho-Associated Kinases; Skin; Skin Temperature; Sympathetic Nervous System; Tetrodotoxin; Vasoconstriction | 2007 |
Pharmacological profile of the clonidine-induced inhibition of vasodepressor sensory outflow in pithed rats: correlation with alpha(2A/2C)-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Blood Vessels; Calcitonin Gene-Related Peptide; Clonidine; Decerebrate State; Electric Stimulation; Heart Rate; Imidazoles; In Vitro Techniques; Isoindoles; Male; Neurons, Afferent; Quinolizines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |