clonidine has been researched along with eedq in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 18 (85.71) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nowak, G; Pilc, A; Zak, J | 1 |
| Barturen, F; Garcia-Sevilla, JA | 1 |
| Engberg, G; Eriksson, E | 1 |
| Agneter, E; Drobny, H; Singer, EA | 1 |
| Takano, Y; Yaksh, TL | 1 |
| Agnati, L; Fredholm, B; Fuxe, K; Härfstrand, A | 1 |
| Enna, SJ; Nomura, S; Pilc, A; Vetulani, J | 1 |
| García-Sevilla, JA; Pineda, J; Ruiz-Ortega, JA; Ugedo, L | 2 |
| Goiny, M; Herrera-Marschitz, M; Meana, JJ | 1 |
| Gabilondo, AM; García-Sevilla, JA | 1 |
| Badia, A; Giraldo, J; Sallés, J | 1 |
| Oriowo, MA | 1 |
| Fröhlich, R; Illes, P; Szabo, B | 1 |
| Badia, A; Giraldo, J; Sallés, J; Vila, E | 1 |
| Ruiz-Ortega, JA; Ugedo, L | 1 |
| Pineda, J; Ruiz-Ortega, JA; Ugedo, L | 1 |
| Agneter, E; Feuerstein, TJ; Sauermann, W; Singer, EA | 1 |
| García-Sevilla, JA; Pineda, J; Ugedo, L | 1 |
| Esteban, S; García-Sevilla, JA; Sastre-Coll, A | 1 |
| Busquets, X; García-Sevilla, JA; Miralles, A; Ribas, C | 1 |
21 other study(ies) available for clonidine and eedq
| Article | Year |
|---|---|
N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, an irreversible receptor inactivator, as a tool for measurement of alpha 2-adrenoceptor occupancy in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Male; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1992 |
Long term treatment with desipramine increases the turnover of alpha 2-adrenoceptors in the rat brain.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Desipramine; Male; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1992 |
Effects of alpha 2-adrenoceptor agonists on locus coeruleus firing rate and brain noradrenaline turnover in N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)-treated rats.
Topics: Animals; Brain; Clonidine; Dose-Response Relationship, Drug; Electrodes; Guanfacine; In Vitro Techniques; Locus Coeruleus; Male; Norepinephrine; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Estimation of agonist dissociation constants at central presynaptic alpha-2 autoreceptors in the absence of autoinhibition.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Norepinephrine; Quinolines; Quinoxalines; Rats; Receptors, Adrenergic, alpha | 1991 |
Relative efficacy of spinal alpha-2 agonists, dexmedetomidine, clonidine and ST-91, determined in vivo by using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, an irreversible antagonist.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Injections, Spinal; Male; Medetomidine; Morphine; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord | 1991 |
Reciprocal interactions between alpha 2-adrenoceptor agonist and neuropeptide Y binding sites in the nucleus tractus solitarius of the rat. A biochemic and autoradiographic analysis.
Topics: Animals; Binding, Competitive; Clonidine; Dioxanes; Idazoxan; Kinetics; Male; Medulla Oblongata; Neuropeptide Y; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Neuropeptide Y; Receptors, Neurotransmitter; Subcellular Fractions | 1989 |
An in vivo procedure for the selective inactivation of rat brain cerebral cortical alpha-adrenoceptors using N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ).
Topics: Adrenergic alpha-Antagonists; Animals; Cell Membrane; Cerebral Cortex; Clonidine; Cyclic AMP; Dihydroalprenolol; Inositol Phosphates; Isoproterenol; Male; Norepinephrine; Prazosin; Quinolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
The stimulatory effect of clonidine through imidazoline receptors on locus coeruleus noradrenergic neurones is mediated by excitatory amino acids and modulated by serotonin.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Catecholamines; Clonidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Extracellular Space; Imidazoline Receptors; Kynurenic Acid; Locus Coeruleus; Male; Methyltyrosines; Neurons; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Serotonin; Sympathetic Nervous System; Sympatholytics; Tyrosine 3-Monooxygenase | 1995 |
In vivo modulation of norepinephrine and glutamate release through imidazoline receptors in the rat central nervous system.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Central Nervous System; Clonidine; Dioxanes; Glutamic Acid; Idazoxan; Imidazoline Receptors; Norepinephrine; Quinolines; Rats; Receptors, Drug | 1995 |
The stimulatory effect of clonidine on locus coeruleus noradrenergic neurons through imidazoline receptors is modulated by excitatory amino acids.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Clonidine; Excitatory Amino Acids; Fenclonine; Imidazoline Receptors; Locus Coeruleus; Male; Methyltyrosines; Neurons; Norepinephrine; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reserpine | 1995 |
Spontaneous withdrawal from long-term treatment with morphine accelerates the turnover of alpha 2-adrenoceptors in the rat brain: up-regulation of receptors associated with increased receptor appearance.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Male; Morphine; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Substance Withdrawal Syndrome; Time Factors; Up-Regulation | 1995 |
Analysis of agonism at functional prejunctional alpha 2-adrenoceptors of rat vas deferens using operational and null approaches.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Algorithms; Alkylation; Animals; Clonidine; Drug Synergism; Electric Stimulation; In Vitro Techniques; Male; Neuromuscular Junction; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Vas Deferens | 1994 |
The prejunctional inhibitory effect of alpha-methylnoradrenaline in the rat vas deferens is not mediated via alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; Imidazoles; Isometric Contraction; Male; Neuromuscular Junction; Nordefrin; Phenoxybenzamine; Phentolamine; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vas Deferens; Vasoconstrictor Agents; Yohimbine | 1995 |
No evidence for functional imidazoline receptors on locus coeruleus neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Imidazoline Receptors; Injections, Intravenous; Locus Coeruleus; Male; Microelectrodes; Neurons; Oxazoles; Quinolines; Rats; Rats, Wistar; Receptors, Drug; Rilmenidine | 1996 |
Modelling the changes induced by chronic desipramine treatment on the factors governing the agonism at prejunctional alpha 2-adrenoceptors.
Topics: Adrenergic Uptake Inhibitors; Animals; Clonidine; Desipramine; Dose-Response Relationship, Drug; Logistic Models; Male; Models, Biological; Muscle, Smooth; Quinolines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vas Deferens; Xylazine | 1996 |
The stimulatory effect of clonidine on locus coeruleus neurons of rats with inactivated alpha 2-adrenoceptors: involvement of imidazoline receptors located in the nucleus paragigantocellularis.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Electrophysiology; Imidazoline Receptors; Locus Coeruleus; Male; Medulla Oblongata; Microinjections; Neurons; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Drug | 1997 |
Receptor reserve and turnover of alpha-2 adrenoceptors that mediate the clonidine-induced inhibition of rat locus coeruleus neurons in vivo.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Locus Coeruleus; Male; Neurons; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 1997 |
The slope parameter of concentration-response curves used as a touchstone for the existence of spare receptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Models, Theoretical; Norepinephrine; Quinolines; Quinoxalines; Rats | 1997 |
Enhanced alpha2A-autoreceptor reserve for clonidine induced by reserpine and cholinomimetic agents in the rat vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoreceptors; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Male; Muscle Contraction; Muscle, Smooth; Neostigmine; Parasympathomimetics; Pilocarpine; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reserpine; Vas Deferens | 1997 |
Effects of imidazoline drugs on tyrosine and tryptophan hydroxylase activity in rat brain in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzofurans; Brain; Clonidine; Dihydroxyphenylalanine; Imidazoles; Male; Quinolines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1999 |
Brain alpha(2)-adrenoceptors in monoamine-depleted rats: increased receptor density, G coupling proteins, receptor turnover and receptor mRNA.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Brain; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Gene Expression Regulation; GTP-Binding Proteins; Idazoxan; Male; Membranes; Norepinephrine; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reserpine; RNA, Messenger; Tritium | 2001 |