clonidine and codeine

clonidine has been researched along with codeine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19909 (32.14)18.7374
1990's3 (10.71)18.2507
2000's11 (39.29)29.6817
2010's5 (17.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Boettcher, C; Bünemann, M; Dees, C; Lohse, MJ; Nikolaev, VO; Zenk, MH1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lawrence, F; Rappolt, RT1
Järvinen, A; Paakkari, I1
Dharmsathaphorn, K; Gertler, SL; Hofmann, AF; Jones, BR; Kelts, DG; Pressman, JH; Steinbach, JH; Stokes, K; Stone, DM; Witztum, KF1
Culnane, M; Dubner, R; Gracely, RH; Max, MB; Schafer, SC1
Sandyk, R1
Mulry, JT1
Javel, AF1
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH1
Charney, DS; Kleber, HD1
Cutler, R; Fishbain, DA; Rosomoff, HL1
Perera, I1
Dunn, GS; Merrick, PM; Montgomery, CJ; Reimer, EJ; Sanderson, PM; Scheepers, LD1
Anderson, D; Bradbury, L; Stones, RW1
Kim, KH; Park, SC1

Reviews

2 review(s) available for clonidine and codeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Opiate detoxification protocols. A clinical manual.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1993, Volume: 5, Issue:1

    Topics: Administration, Cutaneous; Clinical Protocols; Clonidine; Codeine; Female; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Psychiatric Status Rating Scales; Receptors, Opioid; Substance Withdrawal Syndrome

1993

Trials

4 trial(s) available for clonidine and codeine

ArticleYear
Association of pain relief with drug side effects in postherpetic neuralgia: a single-dose study of clonidine, codeine, ibuprofen, and placebo.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:4

    Topics: Aged; Aged, 80 and over; Clinical Trials as Topic; Clonidine; Codeine; Double-Blind Method; Female; Herpes Zoster; Humans; Ibuprofen; Male; Middle Aged; Neuralgia; Pain Measurement; Random Allocation

1988
The effectiveness of clonidine as an analgesic in paediatric adenotonsillectomy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:12

    Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Blood Pressure; Child; Clonidine; Codeine; Consciousness; Deglutition; Double-Blind Method; Female; Fentanyl; Follow-Up Studies; Humans; Incidence; Injections, Intravenous; Intraoperative Care; Male; Morphine; Pain Measurement; Pain, Postoperative; Premedication; Tonsillectomy

1998
Randomized placebo controlled trial of lofexidine hydrochloride for chronic pelvic pain in women.
    Human reproduction (Oxford, England), 2001, Volume: 16, Issue:8

    Topics: Acetaminophen; Adrenergic alpha-Agonists; Anti-Inflammatory Agents, Non-Steroidal; Body Mass Index; Chronic Disease; Clonidine; Codeine; Drug Therapy, Combination; Female; Humans; Pelvic Pain; Placebos; Treatment Outcome

2001
Effect of adding cervical facet joint injections in a multimodal treatment program for long-standing cervical myofascial pain syndrome with referral pain patterns of cervical facet joint syndrome.
    Journal of anesthesia, 2012, Volume: 26, Issue:5

    Topics: Acetaminophen; Anesthetics, General; Chronic Pain; Clonidine; Codeine; Combined Modality Therapy; Double-Blind Method; Exercise Therapy; Female; Follow-Up Studies; Humans; Ibuprofen; Injections; Male; Middle Aged; Myofascial Pain Syndromes; Neck Pain; Pain Measurement; Prospective Studies; Zygapophyseal Joint

2012

Other Studies

22 other study(ies) available for clonidine and codeine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors.
    The Journal of biological chemistry, 2007, Sep-14, Volume: 282, Issue:37

    Topics: Cells, Cultured; Fluorescence Resonance Energy Transfer; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Morphine; Receptors, Opioid, mu

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Outpatient detoxification of heroin addiction, 1969--1973 (methadone, darvon, codeine, clonidine).
    Clinical toxicology, 1979, Volume: 14, Issue:1

    Topics: Clonidine; Codeine; Dextropropoxyphene; Heroin Dependence; Humans; Methadone

1979
Continuous monitoring of ventilation in spontaneously breathing anesthetized rats.
    Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:11

    Topics: Anesthesia; Animals; Blood Pressure; Cardiovascular Agents; Clonidine; Codeine; Heart Rate; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Inbred Strains; Respiration; Respiratory Function Tests; Thyrotropin-Releasing Hormone; Tidal Volume

1989
Limitations of indirect methods of estimating small bowel transit in man.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:7

    Topics: Antidiarrheals; Blood Glucose; Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Clonidine; Codeine; Colon; Disaccharides; Duodenum; Female; Gastrointestinal Motility; Humans; Hydrogen; Intestine, Small; Lactulose; Male; Methods; Xylose

1987
Tourette syndrome: successful treatment with clonidine and oxycodone.
    Journal of neurology, 1986, Volume: 233, Issue:3

    Topics: Adolescent; Clonidine; Codeine; Drug Therapy, Combination; Humans; Male; Oxycodone; Tourette Syndrome

1986
Guanabenz therapy for opiate withdrawal.
    Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:1

    Topics: Adult; Clonidine; Codeine; Guanabenz; Guanidines; Humans; Male; Substance Withdrawal Syndrome

1985
Mixed substance abuse withdrawal treated by clonidine.
    The Journal of the Medical Society of New Jersey, 1983, Volume: 80, Issue:12

    Topics: Adult; Clonidine; Codeine; Glutethimide; Humans; Male; Substance Withdrawal Syndrome

1983
Narcotic discrimination in pigeons.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity

1980
Iatrogenic opiate addiction: successful detoxification with clonidine.
    The American journal of psychiatry, 1980, Volume: 137, Issue:8

    Topics: Clonidine; Codeine; Female; Humans; Middle Aged; Opioid-Related Disorders; Oxycodone; Pain, Intractable; Substance Withdrawal Syndrome

1980
What you need to know: addiction--cough mixture.
    Singapore medical journal, 1997, Volume: 38, Issue:3

    Topics: Acute Disease; Adrenergic alpha-Agonists; Antitussive Agents; Chronic Disease; Clonidine; Codeine; Dopamine Antagonists; Drug Combinations; Drug Overdose; Drug Therapy, Combination; Humans; Opioid-Related Disorders; Promethazine; Thioridazine

1997
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