citrulline and valine

citrulline has been researched along with valine in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199024 (47.06)18.7374
1990's5 (9.80)18.2507
2000's5 (9.80)29.6817
2010's10 (19.61)24.3611
2020's7 (13.73)2.80

Authors

AuthorsStudies
Simon, JP; Stalon, V1
Hensgens, HE; Meijer, AJ1
Batshaw, M; Brusilow, S; Kulovich, S; Nyhan, W; Spector, E; Thoene, J; Walser, M1
Counahan, R; Cox, BD; El-Bishti, M; Ogg, CS1
Horváth, M; Mestyán, J; Schultz, K; Soltész, G1
Rogers, QR; Spensley, MS; Willits, NH; Zicker, SC1
Mattingley, JM1
Schwarz, E1
Jäkel, A; Liappis, N1
Frimpter, GW1
Cohen, PP; Marshall, M1
Bergström, J; Fürst, P; Norée, LO; Vinnars, E1
Menne, F1
Cahill, CF; Felig, P; Marliss, E; Ohman, JL1
Campbell, DJ; Reid, DW; Yakymyshyn, LY1
Hornig, D; Weber, F; Wiss, O1
Geisler, C; Höcker, P; Stacher, A; Wiser, M1
Griffin, GE; Kesner, L; Muntwyler, E; Sanslone, WR1
Evered, DF; Nunn, PB1
Landau, RL; Lugibihl, K2
Kataura, A; Kataura, K1
Chambers, P; Hill, DL1
Aoyagi, K; Narita, M; Ohba, S; Tojo, S1
Meijer, AJ; Van Roermund, CW; Wanders, RJ1
Belkaïd, M; Hervé, G; Penverne, B1
Kee, AJ; Smith, RC1
Flynn, NE; Flynn, SP; Knabe, DA; Wu, G; Yan, W1
Dugan, ME; Lien, KA; Mosenthin, R; Sauer, WC; Souffrant, WB1
Acchiardo, SR; Chiang, TM; Ford, K; Grokulsky, G; Kang, ES; Wang, YB1
Depledge, MH; Galloway, TS; Morrall, CE; Trapido-Rosenthal, HG1
Campbell, E; Philip, R; Wheatley, DN1
Gulyaeva, NV; Gustafsson, MK; Moiseeva, YV; Onufriev, MV; Terenina, NB1
Alley, SC; Benjamin, D; Carter, PJ; Gerber, HP; Grewal, IS; Hayes, B; Hernandez-Ilizaliturri, FJ; Kung-Sutherland, M; McCormick, R; McDonagh, CF; Miyamoto, J; Morris-Tilden, C; Okeley, N; Stone, I1
Dai, W; Li, RT; Liang, L; Lin, SW; Lu, JK; Xiang, Y; Yang, TY; Zhang, Q; Zhang, Y1
El-Bassossy, HM; El-Fawal, R; Fahmy, A; Watson, ML1
Alley, SC; Baker Lee, C; Benjamin, DR; Hengel, SM; Lyon, RP; Nicholas, ND; Sanderson, RJ1
Casas, MG; Delaria, K; Dorywalska, M; Dushin, R; Farias, SE; Foletti, D; Hasa-Moreno, A; Liu, SH; Lui, V; Moine, L; Navaratnam, T; O'Donnell, CJ; Pons, J; Rajpal, A; Shelton, DL; Strop, P; Tran, TT; Zhou, D1
Casanova, R; Gébleux, R; Neri, D; Soltermann, A; Stringhini, M1
Agarwal, P; Chen, SC; Fine, BM; Gibiansky, L; Girish, S; Jin, JY; Kågedal, M; Koppada, N; Li, C; Lu, D; Saad, O; Samineni, D; Wang, B; Wang, X; Xu, J1
Akita, RW; Caculitan, NG; Cheung, TK; Dela Cruz Chuh, J; Haley, B; Kozak, KR; Lee, BC; Liu, Y; Ma, Y; Phung, Q; Pillow, TH; Polson, AG; Sadowsky, J; Sliwkowski, MX; Zhang, D1
Dai, W; He, B; Li, S; Liang, Y; Sun, Y; Wang, X; Wang, Y; Zhang, H; Zhang, Q; Zhang, Y1
An, Z; Anami, Y; Gui, X; Tsuchikama, K; Xiong, W; Yamazaki, CM; Zhang, N1
Fine, BM; Gillespie, WR; Girish, S; Jin, JY; Kågedal, M; Li, C; Lu, D; Samineni, D1
Cao, Z; Kong, Y; Li, T; Liu, W; Ma, Z; Rosenbaum, ER; Song, B; Wan, Z; Yue, X; Zhai, Y1
Chen, F; Dong, K; Dong, LH; Jiang, J; Li, L; Song, HF; Wang, L; Xu, MZ1
Liu, Y; Shen, Y; Tu, J; Ye, Z; Zhang, Y1
Anna, P; Magdalena, D; Magdalena, G; Magdalena, KP; Marta, S; Michal, S; Rafał, S1
Li, S; Lyu, G; Yang, H; Yang, Y1
Aldawod, H; Alhamadsheh, MM; Amin, TU; Balgoname, A; Emara, R; Haque Tuhin, MT; Jiang, G; Liang, D; Pal, A; Patel, AD1
Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF1

Reviews

2 review(s) available for citrulline and valine

ArticleYear
Aminoacidurias due to inherited disorders of metabolism. 2.
    The New England journal of medicine, 1973, Oct-25, Volume: 289, Issue:17

    Topics: Acidosis; Alanine; Amino Acid Metabolism, Inborn Errors; Arginase; Arginine; Carbamates; Citrulline; Dipeptides; Glutarates; Glycine; Histidine; Humans; Hydroxyproline; Hyperglycemia; Infant, Newborn; Keto Acids; Lysine; Malonates; Maple Syrup Urine Disease; Ornithine Carbamoyltransferase; Phosphotransferases; Proline; Sarcosine; Succinates; Urea; Valine

1973
[Feeble mindedness caused by genetic disorders of amino acid metabolism].
    Hippokrates, 1968, May-31, Volume: 39, Issue:10

    Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Citrulline; Glycine; Hartnup Disease; Histidine; Homocystinuria; Humans; Hydroxyproline; Intellectual Disability; Lysine; Maple Syrup Urine Disease; Methionine; Phenylketonurias; Proline; Sarcosine; Succinates; Transferases; Tryptophan; Valine

1968

Other Studies

49 other study(ies) available for citrulline and valine

ArticleYear
L-Ornithine carbamoyltransferase from Saccharomyces cerevisiae: steady-state kinetic analysis.
    European journal of biochemistry, 1977, May-16, Volume: 75, Issue:2

    Topics: Aminobutyrates; Arsenates; Citrulline; Kinetics; Mathematics; Organophosphonates; Ornithine Carbamoyltransferase; Phosphates; Saccharomyces cerevisiae; Structure-Activity Relationship; Valine

1977
The interrelationship between ureogenesis and protein synthesis in isolated rat-liver cells.
    Biochimica et biophysica acta, 1979, Feb-01, Volume: 582, Issue:3

    Topics: Amino Acids; Aminooxyacetic Acid; Ammonia; Animals; Arginine; Citrulline; Cycloheximide; Glucose; Leucine; Liver; Male; Protein Biosynthesis; Rats; Urea; Valine

1979
Neonatal citrllinemia: treatment with keto-analogues of essential amino acids.
    The Journal of pediatrics, 1977, Volume: 90, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Essential; Arginine; Argininosuccinate Synthase; Citrulline; Fibroblasts; Histidine; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Threonine; Tryptophan; Valine

1977
Plasma amino acids in children and adolescents on hemodialysis.
    Kidney international, 1976, Volume: 10, Issue:6

    Topics: Adolescent; Amino Acids; Child; Child Nutritional Physiological Phenomena; Citrulline; Diet; Female; Glycine; Growth; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methylhistidines; Nutritional Physiological Phenomena; Proline; Renal Dialysis; Serine; Tyrosine; Valine

1976
The metabolic effects of glucagon infusion in normoglycaemic and hypoglycaemic small-for-gestational-age infants. II. Changes in plasma amino acids.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1976, Volume: 17, Issue:3

    Topics: Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Citrulline; Glucagon; Gluconeogenesis; Glycine; Humans; Hypoglycemia; Infant, Low Birth Weight; Infant, Newborn; Infant, Small for Gestational Age; Infusions, Parenteral; Isoleucine; Leucine; Liver; Proline; Valine

1976
Concentrations of amino acids in the plasma of neonatal foals with septicemia.
    American journal of veterinary research, 1991, Volume: 52, Issue:7

    Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Arginine; Citrulline; Female; Glycine; Gram-Negative Bacteria; Horse Diseases; Horses; Immunoglobulin G; Isoleucine; Male; Phenylalanine; Proline; Sepsis; Threonine; Valine

1991
Paper chromatography of urinary amino acids. A 30 year survey of dietary influences on the normal pattern, and patients' results.
    Biomedical chromatography : BMC, 1986, Volume: 1, Issue:3

    Topics: Adult; Amino Acids; Child; Chromatography, Paper; Citrulline; Diet; Glutamine; Humans; Hydroxyproline; Infant; Valine

1986
[Biochemical stigmas of human skin surface in old age (author's transl)].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1974, Volume: 12, Issue:3

    Topics: Adult; Aged; Aging; Alanine; Amino Acids; Ammonia; Citrulline; Glutamates; Glycine; Histidine; Humans; Lactates; Pyrrolidonecarboxylic Acid; Skin; Surface Properties; Sweating; Threonine; Urea; Valine

1974
[Free amino acids in the 24 h urine of healthy children (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1974, Volume: 122, Issue:9

    Topics: Adolescent; Age Factors; Alanine; Amino Acids; Aminobutyrates; Carnosine; Child; Chromatography, Ion Exchange; Citrulline; Female; Glycine; Histidine; Humans; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Serine; Sex Factors; Threonine; Tyrosine; Valine

1974
Ornithine transcarbamylase from Streptococcus faecalis and bovine liver. II. Multiple binding sites for carbamyl-P and L-norvaline, correlation with steady state kinetics.
    The Journal of biological chemistry, 1972, Mar-25, Volume: 247, Issue:6

    Topics: Amino Acids; Animals; Binding Sites; Carbamates; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Citrulline; Enterococcus faecalis; Feedback; Hydrogen-Ion Concentration; Kinetics; Liver; Macromolecular Substances; Mathematics; Ornithine; Ornithine Carbamoyltransferase; Phosphates; Phosphoric Acids; Phosphorus Isotopes; Species Specificity; Tritium; Valerates; Valine

1972
Intracellular free amino acid concentration in human muscle tissue.
    Journal of applied physiology, 1974, Volume: 36, Issue:6

    Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine

1974
Plasma amino acid levels in diabetic ketoacidosis.
    Diabetes, 1970, Volume: 19, Issue:10

    Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine

1970
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
    American journal of obstetrics and gynecology, 1971, Sep-15, Volume: 111, Issue:2

    Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine

1971
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1971, Volume: 41, Issue:1

    Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine

1971
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
    Wiener klinische Wochenschrift, 1971, Apr-09, Volume: 83, Issue:14

    Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine

1971
Amino acid content of muscle and plasma with altered pH.
    Metabolism: clinical and experimental, 1970, Volume: 19, Issue:2

    Topics: Acidosis, Respiratory; Alanine; Alkalosis; Amino Acids; Animals; Aspartic Acid; Carbon Dioxide; Cell Membrane; Citrulline; Extracellular Space; Glutamine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Male; Muscles; Partial Pressure; Potassium Deficiency; Rats; Serine; Threonine; Valine

1970
Uptake of amino acids by mucosa of rat colon in vitro.
    European journal of biochemistry, 1968, Volume: 4, Issue:3

    Topics: Animals; Biological Transport; Carbon Isotopes; Citrulline; Colon; Cyanides; Depression, Chemical; Dinitrophenols; Glycine; Histidine; Intestinal Mucosa; Intestinal Secretions; Lysine; Male; Methionine; Rats; Serous Membrane; Valine

1968
Effect of glucagon on concentration of several free amino acids in plasma.
    Metabolism: clinical and experimental, 1969, Volume: 18, Issue:4

    Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine

1969
The comparison of free and bound amino acids between dry and wet types of cerumen.
    The Tohoku journal of experimental medicine, 1967, Volume: 91, Issue:3

    Topics: Amino Acids; Aspartic Acid; Cerumen; Child; Chromatography, Paper; Chromatography, Thin Layer; Citrulline; Glutamates; Glycine; Humans; Lipids; Protein Binding; Valine

1967
The effect of progesterone on the concentration of plasma amino acids in man.
    Metabolism: clinical and experimental, 1967, Volume: 16, Issue:12

    Topics: Acromegaly; Alanine; Amino Acids; Arginine; Citrulline; Cystine; Fasting; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Progesterone; Proline; Proteins; Threonine; Tyrosine; Valine

1967
The biosynthesis of proline by Tetrahymena pyriformis.
    Biochimica et biophysica acta, 1967, Nov-28, Volume: 148, Issue:2

    Topics: Acids; Alanine; Arginine; Carbon Isotopes; Citrulline; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Hydrolases; Ketoglutaric Acids; Kinetics; Metals; Ornithine; Oxidoreductases; Proline; Protein Denaturation; Pyrroles; Tetrahymena; Transaminases; Ureohydrolases; Valine

1967
Regulation of biosynthesis of guanidinosuccinic acid in isolated rat hepatocytes and in vivo.
    Kidney international. Supplement, 1983, Volume: 16

    Topics: Amino Acids; Ammonium Chloride; Animals; Arginine; Citrulline; Guanidines; In Vitro Techniques; Liver; Male; Ornithine; Rats; Rats, Inbred Strains; Succinates; Urea; Valine

1983
Analysis of the control of citrulline synthesis in isolated rat-liver mitochondria.
    European journal of biochemistry, 1984, Jul-16, Volume: 142, Issue:2

    Topics: Acetazolamide; Ammonia; Animals; Bicarbonates; Carbamoyl-Phosphate Synthase (Ammonia); Carbamyl Phosphate; Citrulline; Male; Mitochondria, Liver; Ornithine; Ornithine Carbamoyltransferase; Rats; Rats, Inbred Strains; Valine

1984
In situ behavior of the pyrimidine pathway enzymes in Saccharomyces cerevisiae. 4. The channeling of carbamylphosphate to aspartate transcarbamylase and its partition in the pyrimidine and arginine pathways.
    Archives of biochemistry and biophysics, 1994, Feb-15, Volume: 309, Issue:1

    Topics: Arginine; Aspartate Carbamoyltransferase; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cell Membrane Permeability; Citrulline; Hydrogen-Ion Concentration; Kinetics; Ligases; Ornithine Carbamoyltransferase; Pyrimidines; Saccharomyces cerevisiae; Valine

1994
Organ clearance of tyrosyl-arginine and its effect on amino acid metabolism in young sheep.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:8

    Topics: Aging; Amino Acids; Analgesics; Animals; Arginine; Citrulline; Endorphins; Female; Hindlimb; Intestinal Mucosa; Intestines; Isoleucine; Kidney; Leucine; Liver; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Regional Blood Flow; Sheep; Tyrosine; Valine

1993
Arginine degradation in developing porcine enterocytes.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Aging; Animals; Animals, Newborn; Animals, Suckling; Arginine; Cells, Cultured; Citrulline; Cyclohexanecarboxylic Acids; Intestinal Mucosa; Jejunum; Nitric Oxide Synthase; Nitroarginine; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroline Carboxylate Reductases; Swine; Valine; Weaning

1996
Evaluation of the 15N-isotope dilution technique for determining the recovery of endogenous protein in ileal digestion of pigs: effect of dilution in the precursor pool for endogenous nitrogen secretion.
    Journal of animal science, 1997, Volume: 75, Issue:1

    Topics: Alanine; Animals; Citrulline; Diet; Dietary Proteins; Digestion; Glutamine; Ileum; Indicator Dilution Techniques; Infusions, Intravenous; Leucine; Male; Nitrogen; Nitrogen Isotopes; Proteins; Swine; Time Factors; Trichloroacetic Acid; Urea; Valine

1997
Normal circulating adult human red blood cells contain inactive NOS proteins.
    The Journal of laboratory and clinical medicine, 2000, Volume: 135, Issue:6

    Topics: Arginase; Arginine; Chromatography, Thin Layer; Citrulline; Enzyme Inhibitors; Erythrocytes; Humans; Hydrolysis; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Valine

2000
Characterisation of nitric oxide synthase activity in the tropical sea anemone Aiptasia pallida.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2000, Volume: 125, Issue:4

    Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Epithelial Cells; NADP; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Sea Anemones; Staining and Labeling; Valine

2000
Arginine deprivation and tumour cell death: arginase and its inhibition.
    Molecular and cellular biochemistry, 2003, Volume: 244, Issue:1-2

    Topics: Animals; Arginase; Arginine; Cattle; Cell Death; Cell Division; Cell Line; Citrulline; Dose-Response Relationship, Drug; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Ornithine; Time Factors; Valine

2003
Nitric oxide synthase activity in Fasciola hepatica: a radiometric study.
    Parasitology, 2003, Volume: 126, Issue:Pt 6

    Topics: Animals; Arginase; Cattle; Citrulline; Enzyme Inhibitors; Fasciola hepatica; Guanidines; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Radiometry; Thiourea; Valine

2003
Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas.
    Blood, 2009, Apr-30, Volume: 113, Issue:18

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD19; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Survival; Citrulline; Dimerization; Dipeptides; Drug Resistance, Neoplasm; Female; Flow Cytometry; Gene Dosage; Humans; Immunoconjugates; Immunoenzyme Techniques; Lymphoma, Non-Hodgkin; Lysosomes; Mice; Mice, SCID; Oligopeptides; Receptors, Complement 3d; Rituximab; Valine; Xenograft Model Antitumor Assays

2009
Novel cathepsin B-sensitive paclitaxel conjugate: Higher water solubility, better efficacy and lower toxicity.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Jun-28, Volume: 160, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cathepsin B; Cell Cycle; Cell Line, Tumor; Citrulline; Dipeptides; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Polyethylene Glycols; Tumor Burden; Valine

2012
Arginase inhibition alleviates hypertension in the metabolic syndrome.
    British journal of pharmacology, 2013, Volume: 169, Issue:3

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Arginase; Blood Pressure; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypolipidemic Agents; Insulin Resistance; Male; Metabolic Syndrome; Nitric Oxide; Ornithine; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Valine

2013
Antibody-conjugated drug assay for protease-cleavable antibody-drug conjugates.
    Bioanalysis, 2016, Volume: 8, Issue:1

    Topics: Animals; Biological Assay; Citrulline; Drug Stability; Female; Humans; Immunoconjugates; Oligopeptides; Papain; Rats; Valine

2016
Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Biomarkers; Carbamates; Carboxylesterase; Citrulline; Drug Design; Drug Stability; Humans; Immunoconjugates; Mice; Mice, Knockout; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Structure-Activity Relationship; Valine

2016
Non-internalizing antibody-drug conjugates display potent anti-cancer activity upon proteolytic release of monomethyl auristatin E in the subendothelial extracellular matrix.
    International journal of cancer, 2017, 04-01, Volume: 140, Issue:7

    Topics: Animals; Antibodies; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; CHO Cells; Citrulline; Cricetulus; Endothelium; Extracellular Matrix; Female; Humans; Immunoconjugates; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Oligopeptides; Protein Isoforms; Tenascin; Valine

2017
Platform model describing pharmacokinetic properties of vc-MMAE antibody-drug conjugates.
    Journal of pharmacokinetics and pharmacodynamics, 2017, Volume: 44, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Citrulline; Cohort Studies; Female; Humans; Immunoconjugates; Male; Middle Aged; Models, Biological; Neoplasms; Oligopeptides; Valine; Young Adult

2017
Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody-Drug Conjugates.
    Cancer research, 2017, 12-15, Volume: 77, Issue:24

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Cathepsin B; Cell Line, Tumor; Cells, Cultured; Citrulline; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Immunoconjugates; Oligopeptides; Prodrugs; Proteolysis; Valine

2017
A comparative study of the antitumor efficacy of peptide-doxorubicin conjugates with different linkers.
    Journal of controlled release : official journal of the Controlled Release Society, 2018, 04-10, Volume: 275

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Citrulline; Doxorubicin; Drug Delivery Systems; Drug Liberation; Integrin alphaVbeta3; Melanoma, Experimental; Mice, Inbred C57BL; Peptides, Cyclic; Prodrugs; Valine

2018
Glutamic acid-valine-citrulline linkers ensure stability and efficacy of antibody-drug conjugates in mice.
    Nature communications, 2018, 06-28, Volume: 9, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Breast Neoplasms; Carboxylic Ester Hydrolases; Cell Line, Tumor; Citrulline; Drug Design; Drug Stability; Female; Gene Expression; Glutamic Acid; Humans; Hydrolysis; Immunoconjugates; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Receptor, ErbB-2; Survival Analysis; Valine; Xenograft Model Antitumor Assays

2018
Time-to-Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine-Citrulline-Monomethylauristatin E Antibody-Drug Conjugates.
    CPT: pharmacometrics & systems pharmacology, 2019, Volume: 8, Issue:8

    Topics: Body Weight; Citrulline; Clinical Trials as Topic; Drug Dosage Calculations; Female; Humans; Immunoconjugates; Male; Models, Biological; Neoplasms; Oligopeptides; Peripheral Nervous System Diseases; Time Factors; Valine

2019
Benchmark Examination of Blood Amino Acids Patterns in Phenylketonuria Neonates and Young Children on Phenylalanine-Restricted Dietary Treatment.
    Fetal and pediatric pathology, 2022, Volume: 41, Issue:3

    Topics: Arginine; Benchmarking; Child; Child, Preschool; Citrulline; Diet; Humans; Infant, Newborn; Methionine; Phenylalanine; Phenylketonurias; Proline; Tyrosine; Valine

2022
Conjugating MMAE to a novel anti-HER2 antibody for selective targeted delivery.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:24

    Topics: Animals; Antibodies, Monoclonal; Cell Proliferation; Cell Survival; Citrulline; Drug Delivery Systems; Female; Immunoconjugates; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Oligopeptides; Receptor, ErbB-2; Tumor Cells, Cultured; Valine

2020
EGFR Targeted Cetuximab-Valine-Citrulline (vc)-Doxorubicin Immunoconjugates- Loaded Bovine Serum Albumin (BSA) Nanoparticles for Colorectal Tumor Therapy.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Adsorption; Animals; Cattle; Cell Line, Tumor; Cell Survival; Cetuximab; Citrulline; Colorectal Neoplasms; Doxorubicin; Drug Delivery Systems; Endocytosis; ErbB Receptors; Humans; Immunoconjugates; Mice; Nanoparticles; Particle Size; Proton Magnetic Resonance Spectroscopy; Serum Albumin, Bovine; Tissue Distribution; Valine

2021
Targeted metabolomics analysis of serum and Mycobacterium tuberculosis antigen-stimulated blood cultures of pediatric patients with active and latent tuberculosis.
    Scientific reports, 2022, 03-08, Volume: 12, Issue:1

    Topics: Biomarkers; Blood Culture; Child; Citrulline; Glutamine; Humans; Kynurenine; Latent Tuberculosis; Leucine; Metabolomics; Mycobacterium tuberculosis; Tuberculosis; Valine

2022
Metabolic characterization of amniotic fluid of fetuses with isolated choroid plexus cyst.
    Journal of perinatal medicine, 2022, Oct-26, Volume: 50, Issue:8

    Topics: Amniotic Fluid; Arginine; Aspartic Acid; Choroid Plexus; Citrulline; Coenzyme A; Cysts; Ethanolamines; Female; Glucose; Humans; Hydroxylysine; Isoleucine; Leucine; Pregnancy; Proline; Ultrasonography, Prenatal; Valine

2022
Enhancing the Safety and Efficacy of PSMA-Based Small-Molecule Drug Conjugates by Linker Stabilization and Conjugation to Transthyretin Binding Ligand.
    Journal of medicinal chemistry, 2022, 11-24, Volume: 65, Issue:22

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Citrulline; Humans; Immunoconjugates; Ligands; Mice; Prealbumin; Valine

2022
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
    Andrology, 2023, Volume: 11, Issue:7

    Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine

2023