ci 966 has been researched along with tiagabine in 3 studies
| Studies (ci 966) | Trials (ci 966) | Recent Studies (post-2010) (ci 966) | Studies (tiagabine) | Trials (tiagabine) | Recent Studies (post-2010) (tiagabine) |
|---|---|---|---|---|---|
| 14 | 0 | 4 | 571 | 102 | 111 |
| Protein | Taxonomy | ci 966 (IC50) | tiagabine (IC50) |
|---|---|---|---|
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | 2.2107 | |
| Sodium- and chloride-dependent GABA transporter 1 | Homo sapiens (human) | 0.2213 | |
| Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (house mouse) | 0.1968 | |
| Sodium- and chloride-dependent betaine transporter | Mus musculus (house mouse) | 0.27 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borden, LA; Branchek, TA; Gluchowski, C; Murali Dhar, TG; Smith, KE; Weinshank, RL | 1 |
| Borden, LA; Branchek, TA; Dhar, TG; Gluchowski, C; Smith, KE; Tyagarajan, S; Weinshank, RL | 1 |
| Andrade e Silva, ML; Cunha, WR; Fontana, AC; Magalhães, LG; Mortensen, OV; Pereira, AC; Souza Rezende, KC; Timple, JM | 1 |
3 other study(ies) available for ci 966 and tiagabine
| Article | Year |
|---|---|
Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.
Topics: Animals; Anticonvulsants; Carrier Proteins; Cell Line; Cloning, Molecular; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nicotinic Acids; Nipecotic Acids; Organic Anion Transporters; Oximes; Pyridines; Rats; Recombinant Proteins; Structure-Activity Relationship; Tiagabine; Transfection | 1994 |
Design, synthesis and evaluation of substituted triarylnipecotic acid derivatives as GABA uptake inhibitors: identification of a ligand with moderate affinity and selectivity for the cloned human GABA transporter GAT-3.
Topics: Animals; Binding Sites; Biological Transport; Blood-Brain Barrier; Carrier Proteins; Cell Line; Cloning, Molecular; Drug Design; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Ligands; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Organic Anion Transporters; Proline; Rats | 1994 |
The lignan (-)-hinokinin displays modulatory effects on human monoamine and GABA transporter activities.
Topics: 4-Butyrolactone; Attention Deficit Disorder with Hyperactivity; Benzodioxoles; Dioxoles; Dopamine; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; Humans; Lignans; Molecular Structure; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism | 2013 |