Page last updated: 2024-08-18

chalcone and warfarin

chalcone has been researched along with warfarin in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.41)18.7374
1990's6 (16.22)18.2507
2000's9 (24.32)29.6817
2010's13 (35.14)24.3611
2020's7 (18.92)2.80

Authors

AuthorsStudies
Gray, TI; Pelter, A; Ward, RS1
Boudet, AM; Harada, H; Marigo, G; Ranjeva, R1
Cunningham, S; Kollmeyer, WD; Stacey, G1
Hasegawa, T; Iwashima, A; Nishino, A; Nishino, H; Okuyama, T; Takata, M; Takayasu, J; Tokuda, H1
Kim, SH; Kim, SJ; Shin, JM; Shin, W1
Hakamata, Y; Hayashi, T; Hirayama, Y; Satake, M; Sekita, S; Shirota, O; Takizawa, K; Yanagawa, T1
Abeygunawardana, C; Dinkova-Kostova, AT; Talalay, P1
Akendengue, B; Hocquemiller, R; Laurens, A; Ngou-Milama, E1
Bozak, RE; Dinkova-Kostova, AT; Hicks, RJ; Massiah, MA; Talalay, P1
Eckermann, C; Eckermann, S; Schmidt, J; Schneider, B; Schröder, G; Schröder, J; Strack, D1
Hatano, T; Ito, H; Tanuma, S; Uchiumi, F; Yoshida, T1
Kawanishi, K; Moriyasu, M; Ueda, H1
Akihisa, T; Iizuka, M; Iwatsuki, K; Mukainaka, T; Nishino, H; Ogasawara, K; Schneider, S; Suzuki, T; Tokuda, H; Ukiya, M1
Carbonetti, A; Delle Monache, F; Delle Monache, G; Trani, M1
Elvin-Lewis, MP; Lewis, WH; Okunade, AL1
Lee, FS; Wang, QE; Wang, X1
Curini, M; Epifano, F; Genovese, S; Menghini, L1
Bhatia, G; Khanna, AK; Kumar, M; Modukuri, RK; Rai, S; Sashidhara, KV; Shukla, R; Sonkar, R1
Kase, Y; Kobayashi, H; Lee, KK; Omiya, Y; Yuzurihara, M1
Borges, F; Kachler, S; Klotz, KN; Matos, MJ; Santana, L; Uriarte, E; Vazquez-Rodriguez, S1
Pan, S; Ruan, J; Wang, Y; Wei, H; Wu, G; Yang, X; Zhang, X1
Ali, S; Sarkar, J; Sashidhara, KV; Singh, N; Sinha, S1
Mandi, P; Nantasenamat, C; Pingaew, R; Prachayasittikul, S; Prachayasittikul, V; Ruchirawat, S; Saekee, A1
Dai, Y; Qin, L; Shen, XY; Wang, PL; Yao, XS; Yao, ZH; Zhang, FX1
Armesto-Quintas, G; Borges, F; Lama López, R; Matos, MJ; Muñoz Crego, A; Santana, L; Santos, Y; Serra, S; Uriarte, E; Vazquez-Rodriguez, S1
Alvarez-Idaboy, JR; Galano, A; Mazzone, G; Russo, N1
Abou-Zied, OK; Ghasemi, A; Karimi-Jafari, MH; Khammari, A; Khoobi, M; Saboury, AA; Yousefinejad, S1
Chang, KH; Chen, CM; Chiu, YJ; Huang, CC; Lee, SY; Lee-Chen, GJ; Lin, W; Yang, SM1
Bahrami, A; Garcia-Canovas, F; Garcia-Molina, F; Hassan Khan, MT; Munoz-Munoz, J; Saboury, AA; Zolghadri, S1
Chen, YH; Kuo, IC; Lee, CK; Lee, JH; Lee, TH; Mei, HC1
Dong, J; Gao, J; Wang, Y; Zhang, W1
Danduga, RCSR; Kola, PK; Konidala, SK; Kotra, V1
Alanazi, MM; Amran, SI; Biswas, S; Chander, S; Das, B; Hadda, TB; Hasan, AH; Jamalis, J; Murugesan, S; Pratama, MRF; Shakya, S1
Cao, D; Dong, B; Han, Y; Lin, W; Liu, Q; Shan, Y; Sun, Y; Wang, KN; Xing, M; Zhu, Y1
Biswas, S; Chander, S; Das, B; Hasan, AH; Hussain, FHS; Jamalis, J; Jamil, S; Murugesan, S; Pratama, MRF; Shakya, S1
Kumar, A; Kumar, S1
Çelik Onar, H; Ece, A; Erçağ, E; Gülçin, İ; Özden, EM; Taslak, HD1

Reviews

5 review(s) available for chalcone and warfarin

ArticleYear
Recent advances in the fight against leishmaniasis with natural products.
    Parasite (Paris, France), 1999, Volume: 6, Issue:1

    Topics: Alkaloids; Animals; Antiprotozoal Agents; Chalcone; Chalcones; Coumarins; Drug Evaluation, Preclinical; Furans; Lactones; Leishmania; Leishmaniasis; Molecular Structure; Phytotherapy; Plant Extracts; Plants, Medicinal; Quinones; Terpenes

1999
Aldose reductase inhibitors from the nature.
    Current medicinal chemistry, 2003, Volume: 10, Issue:15

    Topics: Acids, Carbocyclic; Aldehyde Reductase; Animals; Chalcone; Coumarins; Ellagic Acid; Enzyme Inhibitors; Flavonoids; Gossypol; Humans; Monoterpenes; Stilbenes; Structure-Activity Relationship

2003
Natural antimycobacterial metabolites: current status.
    Phytochemistry, 2004, Volume: 65, Issue:8

    Topics: Alkaloids; Antitubercular Agents; Chalcone; Chromones; Coumarins; Flavonoids; Microbial Sensitivity Tests; Peptides; Phenols; Plant Preparations; Saponins; Steroids; Terpenes

2004
Chemistry and pharmacology of oxyprenylated secondary plant metabolites.
    Phytochemistry, 2007, Volume: 68, Issue:7

    Topics: Alkaloids; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Asteraceae; Chalcone; Coumarins; Molecular Structure; Plant Extracts; Rutaceae

2007
A comprehensive review on tyrosinase inhibitors.
    Journal of enzyme inhibition and medicinal chemistry, 2019, Volume: 34, Issue:1

    Topics: Agaricales; Animals; Chalcone; Coumarins; Enzyme Inhibitors; Flavonoids; Humans; Monophenol Monooxygenase; Resveratrol

2019

Other Studies

32 other study(ies) available for chalcone and warfarin

ArticleYear
The carbon-13 nuclear magnetic resonance spectra of flavonoids and related compounds.
    Journal of the Chemical Society. Perkin transactions 1, 1976, Issue:23

    Topics: Chalcone; Coumarins; Flavonoids; Isoflavones; Magnetic Resonance Spectroscopy

1976
Phenolic metabolism in petunia tissues. I. Characteristic responses of enzymes involved in different steps of polyphenol synthesis to different hormonal influences.
    Biochimica et biophysica acta, 1975, Jul-14, Volume: 399, Issue:1

    Topics: Alcohol Oxidoreductases; Cells, Cultured; Chalcone; Cinnamates; Coumarins; Culture Media; Flavonoids; Intramolecular Lyases; Isomerases; Ligases; Lignin; Malate Dehydrogenase; Mixed Function Oxygenases; Phenols; Phenylalanine Ammonia-Lyase; Phosphogluconate Dehydrogenase; Plants; Time Factors

1975
Chemical control of interstrain competition for soybean nodulation by Bradyrhizobium japonicum.
    Applied and environmental microbiology, 1991, Volume: 57, Issue:7

    Topics: Benzoates; Benzophenones; Chalcone; Cloning, Molecular; Coumarins; Flavonoids; Gene Expression; Genes, Bacterial; Glycine max; Isoflavones; Molecular Structure; Rhizobiaceae; Symbiosis

1991
Anti-tumor-promotion by principles obtained from Angelica keiskei.
    Planta medica, 1991, Volume: 57, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Calmodulin; Chalcone; Coumarins; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Molecular Structure; Phospholipids

1991
Structure-taste correlations in sweet dihydrochalcone, sweet dihydroisocoumarin, and bitter flavone compounds.
    Journal of medicinal chemistry, 1995, Oct-13, Volume: 38, Issue:21

    Topics: Chalcone; Chalcones; Chemical Phenomena; Chemistry, Physical; Coumarins; Crystallization; Crystallography, X-Ray; Flavones; Flavonoids; Isocoumarins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Structure-Activity Relationship; Sweetening Agents; Taste; Thermodynamics

1995
Antiandrogenic natural Diels--Alder-type adducts from Brosimum rubescens.
    Journal of natural products, 1997, Volume: 60, Issue:10

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgen Receptor Antagonists; Animals; Chalcone; Chromatography, High Pressure Liquid; Coumarins; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Peru; Plant Epidermis; Plants, Medicinal; Rats; Rats, Wistar; Spectrometry, Mass, Fast Atom Bombardment

1997
Chemoprotective properties of phenylpropenoids, bis(benzylidene)cycloalkanones, and related Michael reaction acceptors: correlation of potencies as phase 2 enzyme inducers and radical scavengers.
    Journal of medicinal chemistry, 1998, Dec-17, Volume: 41, Issue:26

    Topics: Animals; Anticarcinogenic Agents; Chalcone; Cinnamates; Coumarins; Enzyme Induction; Free Radical Scavengers; Liver Neoplasms, Experimental; Luminescent Measurements; Magnetic Resonance Spectroscopy; Mice; Molecular Conformation; NAD(P)H Dehydrogenase (Quinone); Structure-Activity Relationship; Superoxides; Tumor Cells, Cultured

1998
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Mar-13, Volume: 98, Issue:6

    Topics: Animals; Benzylidene Compounds; Butanones; Carcinoma, Hepatocellular; Chalcone; Cinnamates; Coumarins; Cyclohexanones; Cyclopentanes; Enzyme Induction; FMN Reductase; Glutathione; Glutathione Transferase; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; NADH, NADPH Oxidoreductases; Sulfhydryl Compounds; Tumor Cells, Cultured

2001
Stilbenecarboxylate biosynthesis: a new function in the family of chalcone synthase-related proteins.
    Phytochemistry, 2003, Volume: 62, Issue:3

    Topics: Acyltransferases; Amino Acid Sequence; Amino Acid Substitution; Benzopyrans; Chalcone; Cloning, Molecular; Coenzyme A; Coumarins; Decarboxylation; Electrophoresis, Polyacrylamide Gel; Hydrangea; Isocoumarins; Molecular Sequence Data; Recombinant Proteins; Salicylates; Sequence Homology, Amino Acid; Stilbenes; Substrate Specificity

2003
Transcriptional suppression of the HIV promoter by natural compounds.
    Antiviral research, 2003, Volume: 58, Issue:1

    Topics: Anti-HIV Agents; Chalcone; Coumarins; Flavonoids; Gene Expression Regulation, Viral; HIV; HIV Infections; Humans; Hydrolyzable Tannins; Jurkat Cells; Promoter Regions, Genetic; Tannins; Tetradecanoylphorbol Acetate; Transfection

2003
Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects.
    Cancer letters, 2003, Nov-25, Volume: 201, Issue:2

    Topics: Angelica; Anticarcinogenic Agents; Antigens, Viral; Burkitt Lymphoma; Carcinogens; Chalcone; Chemoprevention; Coumarins; Ether; Flavanones; Humans; Hydroxylamines; Molecular Structure; Nitric Oxide Donors; Plant Extracts; Plant Stems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2003
Dihydrochalcones and coumarins of Esenbeckia grandiflora subsp. brevipetiolata.
    Fitoterapia, 2004, Volume: 75, Issue:1

    Topics: Brazil; Chalcone; Coumarins; Humans; Medicine, Traditional; Phytotherapy; Plant Extracts; Plant Leaves; Plant Roots; Plants, Medicinal

2004
Isolation and purification of inflacoumarin A and licochalcone A from licorice by high-speed counter-current chromatography.
    Journal of chromatography. A, 2004, Sep-03, Volume: 1048, Issue:1

    Topics: Chalcone; Chalcones; Chromatography, High Pressure Liquid; Coumarins; Countercurrent Distribution; Glycyrrhiza; Magnetic Resonance Spectroscopy

2004
Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chalcone; Coumarins; Edema; Microsomes; Rats

2011
Antispasmodic effect of shakuyakukanzoto extract on experimental muscle cramps in vivo: role of the active constituents of Glycyrrhizae radix.
    Journal of ethnopharmacology, 2013, Jan-09, Volume: 145, Issue:1

    Topics: Animals; Animals, Outbred Strains; Chalcone; Chalcones; Coumarins; Dantrolene; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drugs, Chinese Herbal; Electric Stimulation; Flavanones; Glucosides; Glycyrrhetinic Acid; Glycyrrhiza; Male; Mice; Muscle Contraction; Muscle Cramp; Muscle, Skeletal; Paeonia; Parasympatholytics; Phytotherapy; Plant Roots; Rats; Rats, Wistar; Rotarod Performance Test; Tibial Nerve

2013
Chalcone-based derivatives as new scaffolds for hA3 adenosine receptor antagonists.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:5

    Topics: Animals; Binding, Competitive; Chalcone; CHO Cells; Coumarins; Cricetinae; Cricetulus; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Structure-Activity Relationship; Thiophenes

2013
Chalcone derivatives from the fern Cyclosorus parasiticus and their anti-proliferative activity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 60

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Coumarins; Ferns; Hep G2 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Plant Extracts; Plant Leaves

2013
Anti-tumour activity of a novel coumarin-chalcone hybrid is mediated through intrinsic apoptotic pathway by inducing PUMA and altering Bax/Bcl-2 ratio.
    Apoptosis : an international journal on programmed cell death, 2014, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Coumarins; Cytochromes c; Female; G2 Phase Cell Cycle Checkpoints; Heterografts; Humans; M Phase Cell Cycle Checkpoints; Membrane Potential, Mitochondrial; Mice; Mice, SCID; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Uterine Cervical Neoplasms

2014
Synthesis, biological evaluation and molecular docking of novel chalcone-coumarin hybrids as anticancer and antimalarial agents.
    European journal of medicinal chemistry, 2014, Oct-06, Volume: 85

    Topics: Antimalarials; Antineoplastic Agents; Cell Line, Tumor; Chalcone; Chemistry Techniques, Synthetic; Coumarins; Cysteine Endopeptidases; Humans; Molecular Docking Simulation; Plasmodium falciparum; Protein Conformation; Triazoles; Tubulin

2014
Identification of metabolites of PSORALEAE FRUCTUS in rats by ultra performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry analysis.
    Journal of pharmaceutical and biomedical analysis, 2015, Aug-10, Volume: 112

    Topics: Administration, Oral; Animals; Chalcone; Chromatography, High Pressure Liquid; Coumarins; Drug Interactions; Drugs, Chinese Herbal; Flavanones; Fruit; Furocoumarins; Isoflavones; Male; Medicine, Chinese Traditional; Phenols; Plant Extracts; Psoralea; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry

2015
Design, synthesis and antibacterial study of new potent and selective coumarin-chalcone derivatives for the treatment of tenacibaculosis.
    Bioorganic & medicinal chemistry, 2015, Nov-01, Volume: 23, Issue:21

    Topics: Animals; Anti-Bacterial Agents; Aquaculture; Chalcone; Coumarins; Drug Design; Escherichia coli; Fish Diseases; Fishes; Flavobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Tenacibaculum

2015
Coumarin-Chalcone Hybrids as Peroxyl Radical Scavengers: Kinetics and Mechanisms.
    Journal of chemical information and modeling, 2016, 04-25, Volume: 56, Issue:4

    Topics: Chalcone; Coumarins; Free Radical Scavengers; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Conformation; Peroxides; Solvents; Water

2016
Insights into the molecular interaction between two polyoxygenated cinnamoylcoumarin derivatives and human serum albumin.
    Physical chemistry chemical physics : PCCP, 2017, Apr-12, Volume: 19, Issue:15

    Topics: Binding Sites; Calorimetry; Chalcone; Circular Dichroism; Coumarins; Fluorescence Resonance Energy Transfer; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Serum Albumin, Human; Spectrometry, Fluorescence; Static Electricity; Thermodynamics

2017
Novel synthetic chalcone-coumarin hybrid for Aβ aggregation reduction, antioxidation, and neuroprotection.
    CNS neuroscience & therapeutics, 2018, Volume: 24, Issue:12

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Antioxidants; Cell Line, Tumor; Chalcone; Coumarins; Dose-Response Relationship, Drug; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Inhibitory Concentration 50; Neuroblastoma; Neuronal Outgrowth; Protein Aggregates; Reactive Oxygen Species; RNA Interference; RNA, Messenger; Transfection

2018
Characterizing Tyrosinase Modulators from the Roots of
    Molecules (Basel, Switzerland), 2019, Sep-10, Volume: 24, Issue:18

    Topics: Angelica; Chalcone; Chalcones; Chromatography, Liquid; Coumarins; Enzyme Inhibitors; Monophenol Monooxygenase; Plant Roots; Tandem Mass Spectrometry; Umbelliferones

2019
Design, synthesis and bioactivity evaluation of coumarin-chalcone hybrids as potential anticancer agents.
    Bioorganic chemistry, 2020, Volume: 95

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Chalcone; Coumarins; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fluorescent Dyes; HCT116 Cells; Humans; Inhibitory Concentration 50; Precision Medicine; Reactive Oxygen Species; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase

2020
Coumarin-chalcone hybrids targeting insulin receptor: Design, synthesis, anti-diabetic activity, and molecular docking.
    Bioorganic chemistry, 2020, Volume: 104

    Topics: Administration, Oral; Animals; Antigens, CD; Chalcone; Coumarins; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Hypoglycemic Agents; Injections, Intraperitoneal; Male; Molecular Docking Simulation; Molecular Structure; Rats; Rats, Wistar; Receptor, Insulin; Streptozocin; Structure-Activity Relationship

2020
Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and molecular dynamics simulation.
    Bioorganic chemistry, 2022, Volume: 119

    Topics: Acetylcholinesterase; Alzheimer Disease; Cells, Cultured; Chalcone; Cholinesterase Inhibitors; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Thiophenes

2022
Two Ratiometric Fluorescent Probes Based on the Hydroxyl Coumarin Chalcone Unit with Large Fluorescent Peak Shift for the Detection of Hydrazine in Living Cells.
    Analytical chemistry, 2022, 09-20, Volume: 94, Issue:37

    Topics: Carbon; Chalcone; Chalcones; Coumarins; Fluorescent Dyes; Humans; Hydrazines; Hydroxyl Radical; Phenols; Pyrazoles; Soil; Spectrometry, Fluorescence; Water

2022
Design, synthesis, anti-acetylcholinesterase evaluation and molecular modelling studies of novel coumarin-chalcone hybrids.
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:21

    Topics: Acetylcholinesterase; Chalcone; Chalcones; Cholinesterase Inhibitors; Coumarins; Molecular Docking Simulation; Molecular Dynamics Simulation; Spectroscopy, Fourier Transform Infrared

2023
Synthesis, Computational and Pharmacological Evaluation of 7-(2-(2- (3- (Substituted Phenyl) Acryloyl) Phenoxy) Ethoxy)-4-Methyl-2H-Chromen- 2-Ones as CNS Agents.
    Central nervous system agents in medicinal chemistry, 2023, Volume: 23, Issue:1

    Topics: Animals; Central Nervous System Agents; Chalcone; Coumarins; Diazepam; Mice; Prospective Studies; Structure-Activity Relationship

2023
Novel coumarin-chalcone derivatives: Synthesis, characterization, antioxidant, cyclic voltammetry, molecular modelling and biological evaluation studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors.
    Chemico-biological interactions, 2023, Sep-25, Volume: 383

    Topics: Acetylcholinesterase; Antioxidants; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Chalcone; Cholinesterase Inhibitors; Coumarins; Glycoside Hydrolases; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship

2023
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