celecoxib and warfarin

celecoxib has been researched along with warfarin in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	14 (66.67)	29.6817
2010's	6 (28.57)	24.3611
2020's	1 (4.76)	2.80

Authors

Authors	Studies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Abadi, AH; Abdel-Halim, M; Engel, M; Fathalla, RK; Hammam, MA; Hartmann, RW; Hefnawy, A; Keeton, AB; Maher, A; Maxuitenko, Y; Piazza, GA; Racheed, NAS; Sigler, S	1
Frank, DA; Haase, KK; Lane, L; Rojas-Fernandez, CH	1
Porterfield, LM	1
Geis, GS; Harper, K; Hubbard, RC; Karim, A; Piergies, A; Slater, M; Tolbert, D; Wallemark, CB	1
Mersfelder, TL; Stewart, LR	1
Davis, JV; Linder, JD; Mönkemüller, KE; Wilcox, CM	1
Killen, JP	1
Dubisar, BM; Farrar, C; Lea, JW; Stoner, SC	1
Egan, M; Morreale, AP; Plowman, BK; Schaefer, MG	1
Atac, B; Daly, AK; Gupta, S; Malhi, H	1
Chan, AL	1
Bush, TM; Chakravarty, EF; Chung, L; Kearns, P; Wang, C	1
Dayani, PN; Holekamp, NM; Siddiqi, OK	1
Al-Wabli, R; El-Haggar, R; Fouad, M	1

Reviews

1 review(s) available for celecoxib and warfarin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for celecoxib and warfarin

Article	Year
Celecoxib does not significantly alter the pharmacokinetics or hypoprothrombinemic effect of warfarin in healthy subjects. Journal of clinical pharmacology, 2000, Volume: 40, Issue:6 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Celecoxib; Drug Interactions; Female; Humans; Male; Middle Aged; Prothrombin Time; Pyrazoles; Stereoisomerism; Sulfonamides; Warfarin	2000
Interaction of rofecoxib and celecoxib with warfarin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Jul-01, Volume: 60, Issue:13 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Celecoxib; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Synergism; Female; Humans; International Normalized Ratio; Isoenzymes; Lactones; Male; Membrane Proteins; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Warfarin	2003

Article

Year

Celecoxib does not significantly alter the pharmacokinetics or hypoprothrombinemic effect of warfarin in healthy subjects.

Journal of clinical pharmacology, 2000, Volume: 40, Issue:6

Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Celecoxib; Drug Interactions; Female; Humans; Male; Middle Aged; Prothrombin Time; Pyrazoles; Stereoisomerism; Sulfonamides; Warfarin

2000

Interaction of rofecoxib and celecoxib with warfarin.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Jul-01, Volume: 60, Issue:13

Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Celecoxib; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Synergism; Female; Humans; International Normalized Ratio; Isoenzymes; Lactones; Male; Membrane Proteins; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Warfarin

2003

Other Studies

18 other study(ies) available for celecoxib and warfarin

Article	Year
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
From Celecoxib to a Novel Class of Phosphodiesterase 5 Inhibitors: Trisubstituted Pyrazolines as Novel Phosphodiesterase 5 Inhibitors with Extremely High Potency and Phosphodiesterase Isozyme Selectivity. Journal of medicinal chemistry, 2021, 04-22, Volume: 64, Issue:8 Topics: Animals; Blood Proteins; Celecoxib; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Design; Female; Half-Life; Humans; Isoenzymes; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phosphodiesterase 5 Inhibitors; Protein Binding; Pyrazoles; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship	2021
Potential interaction between celecoxib and warfarin. The Annals of pharmacotherapy, 2000, Volume: 34, Issue:5 Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Celecoxib; Drug Interactions; Female; Geriatric Assessment; Humans; International Normalized Ratio; Pyrazoles; Sulfonamides; Warfarin	2000
Why is this patient starting to bruise? RN, 2000, Volume: 63, Issue:5 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Celecoxib; Drug Monitoring; Ecchymosis; Humans; Male; Nursing Assessment; Pyrazoles; Sulfonamides; Warfarin	2000
Warfarin and celecoxib interaction. The Annals of pharmacotherapy, 2000, Volume: 34, Issue:3 Topics: Aged; Anticoagulants; Celecoxib; Cyclooxygenase Inhibitors; Drug Interactions; Female; Humans; International Normalized Ratio; Pyrazoles; Sulfonamides; Warfarin	2000
Cyclooxygenase-2 inhibitor celecoxib: a possible cause of gastropathy and hypoprothrombinemia. Southern medical journal, 2000, Volume: 93, Issue:9 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arthritis; Atrial Fibrillation; Bicarbonates; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Gastrointestinal Hemorrhage; Hip Joint; Humans; Hypoprothrombinemias; Incidence; Intestinal Mucosa; Isoenzymes; Lactones; Male; Membrane Proteins; Mucus; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Warfarin	2000
The coxibs, selective inhibitors of cyclooxygenase-2. The New England journal of medicine, 2001, Dec-06, Volume: 345, Issue:23 Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Humans; International Normalized Ratio; Isoenzymes; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Warfarin	2001
Possible international normalized ratio elevation associated with celecoxib and warfarin in an elderly psychiatric patient. Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5 Topics: Anticoagulants; Celecoxib; Cyclooxygenase Inhibitors; Drug Interactions; Drug Therapy, Combination; Humans; International Normalized Ratio; Male; Middle Aged; Prothrombin Time; Psychotic Disorders; Pyrazoles; Sulfonamides; Warfarin	2003
Warfarin and celecoxib interaction in the setting of cytochrome P450 (CYP2C9) polymorphism with bleeding complication. Postgraduate medical journal, 2004, Volume: 80, Issue:940 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arthralgia; Aryl Hydrocarbon Hydroxylases; Celecoxib; Cytochrome P-450 CYP2C9; Drug Interactions; Female; Hemorrhage; Humans; International Normalized Ratio; Polymorphism, Genetic; Pyrazoles; Sulfonamides; Warfarin	2004
Celecoxib-induced deep-vein thrombosis. The Annals of pharmacotherapy, 2005, Volume: 39, Issue:6 Topics: Anticoagulants; Celecoxib; Cyclooxygenase Inhibitors; Enoxaparin; Gout; Humans; International Normalized Ratio; Male; Middle Aged; Prothrombin Time; Pyrazoles; Risk Factors; Sulfonamides; Venous Thrombosis; Warfarin	2005
Bleeding complications in patients on celecoxib and warfarin. Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:5 Topics: Aged; Anticoagulants; Celecoxib; Cyclooxygenase 2 Inhibitors; Databases, Factual; Drug Interactions; Drug Therapy, Combination; Female; Hemorrhage; Hospitals, Teaching; Humans; Middle Aged; Pyrazoles; Retrospective Studies; Sulfonamides; Warfarin	2005
Safety of intravitreal injections in patients receiving warfarin anticoagulation. American journal of ophthalmology, 2007, Volume: 144, Issue:3 Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Anticoagulants; Aptamers, Nucleotide; Aspirin; Celecoxib; Choroidal Neovascularization; Drug Therapy, Combination; Eye Hemorrhage; Female; Humans; Injections; Macular Degeneration; Male; Middle Aged; Pyrazoles; Retrospective Studies; Sulfonamides; Vascular Endothelial Growth Factor A; Vitreous Body; Warfarin	2007
Synthesis, In-vivo and In-vitro Anti-inflammatory Evaluation of some Novel Coumarin Derivatives. Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2018, Volume: 17, Issue:2 Topics: Albumins; Animals; Anti-Inflammatory Agents; Celecoxib; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Erythrocyte Membrane; Formaldehyde; Hemolysis; Male; Molecular Structure; Protein Denaturation; Rats; Structure-Activity Relationship	2018