cd 437 and adarotene
cd 437 has been researched along with adarotene in 13 studies
Compound Research Comparison
| Studies (cd 437) | Trials (cd 437) | Recent Studies (post-2010) (cd 437) | Studies (adarotene) | Trials (adarotene) | Recent Studies (post-2010) (adarotene) |
|---|---|---|---|---|---|
| 134 | 0 | 26 | 43 | 1 | 25 |
Research
Studies (13)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (76.92) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Carminati, P; Cincinelli, R; Dallavalle, S; Gaetano, C; Giannini, G; Illy, B; Merlini, L; Penco, S; Pisano, C; Supino, R; Vesci, L; Zuco, V; Zunino, F | 1 |
| Bruey-Sedano, N; Dawson, MI; Farhana, L; Fontana, JA; Harris, DL; Hobbs, PD; James, SY; Jong, L; Lange, CW; Leid, M; Liu, G; Peterson, VJ; Rishi, AK; Zhang, XK | 1 |
| Carella, S; Carminati, P; Cincinelli, R; Dallavalle, S; De Zani, D; Garattini, E; Giannini, G; Merlini, L; Nannei, R; Penco, S; Pisano, C; Vesci, L; Zanchi, C; Zuco, V; Zunino, F | 1 |
| Arumugarajah, S; Bhuiyan, M; Chao, WR; Dawson, MI; Farhana, L; Fontana, JA; Fukushi, J; Han, YH; Harris, DL; Hobbs, PD; Jong, L; Liu, G; Mustelin, T; Patel, BB; Sani, BP; Schiff, LJ; Stallcup, WB; Su, Y; Tautz, L; Waleh, N; Xia, Z; Ye, M; Zhang, XK | 1 |
| Bhuiyan, M; Chao, WR; Dawson, MI; Farhana, L; Feng, GS; Fontana, JA; Han, YH; Hobbs, PD; Jiang, T; Jong, L; Macchiarulo, A; Nuti, R; Pang, Y; Patel, B; Pellicciari, R; Su, Y; Tautz, L; Waleh, N; Xia, Z; Xue, LP; Ye, M; Zhang, XK | 1 |
| Castro, DJ; Correa, RG; Das, JK; Dawson, MI; Farhana, L; Fontana, JA; Oshima, RG; Reed, JC; Xia, Z; Yu, J | 2 |
| Carminati, P; Chiarucci, I; Diomede, L; Ferrara, FF; Garattini, E; Gianni', M; Kalac, Y; Merlini, L; Parrella, E; Pisano, C; Simoni, D; Terao, M; Zanier, R | 1 |
| Aulicino, C; Barbarino, M; Beretta, GL; Bucci, F; Carminati, P; Lanzi, C; Pisano, C; Supino, R; Zanchi, C; Zanier, R; Zuco, V; Zunino, F | 1 |
| Kadara, H; Lotan, D; Lotan, R; Pisano, C; Schroeder, CP | 1 |
| Barzago, MM; Carminati, P; Dallavalle, S; Diomede, L; Fratelli, M; Garattini, E; Giannì, M; Kurosaki, M; Merlini, L; Parrella, E; Pisano, C; Raska, I; Rochette-Egly, C; Tavecchio, M; Terao, M | 1 |
| Antoccia, A; Boldetti, A; Cenciarelli, C; Di Francesco, AM; Erba, E; Fratelli, M; Garattini, E; Gianni', M; Merlini, L; Paroni, G; Pisano, C; Riccardi, R; Tavecchio, M; Terao, M; Valli, C | 1 |
| Ausubel, FM; Conery, AL; Fricke, N; Fuchs, BB; Gao, H; Gilmore, MS; Hendricks, GL; Keohane, CE; Kim, W; Lee, K; Mylonakis, E; Pan, W; Rajamuthiah, R; Shen, S; Steele, AD; Van Tyne, D; Vlahovska, PM; Wuest, WM; Zhu, W | 1 |
Other Studies
13 other study(ies) available for cd 437 and adarotene
| Article | Year |
|---|---|
A novel atypical retinoid endowed with proapoptotic and antitumor activity.
Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Cinnamates; DNA Damage; Drug Screening Assays, Antitumor; Female; Humans; Melanoma; Mice; Mice, Nude; Ovarian Neoplasms; Protein Isoforms; Receptors, Retinoic Acid; Retinoids; Structure-Activity Relationship; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured | 2003 |
Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest.
Topics: Adamantane; Antineoplastic Agents; Apoptosis; Binding, Competitive; Cell Division; Cell Line, Tumor; Cinnamates; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Drug Design; Drug Screening Assays, Antitumor; Humans; Ligands; Models, Molecular; Molecular Conformation; Naphthalenes; Quantitative Structure-Activity Relationship; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcriptional Activation | 2004 |
Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity.
Topics: Acrylates; Adamantane; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Retinoids; Stereoisomerism; Structure-Activity Relationship | 2005 |
An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and
Topics: Adamantane; Angiogenesis Inhibitors; Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Cinnamates; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Endothelial Cells; Humans; In Vitro Techniques; Microcirculation; Protein Tyrosine Phosphatases; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Cytoplasmic and Nuclear; Retinoids; Stereoisomerism | 2007 |
Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and
Topics: Adamantane; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Cinnamates; Dimerization; Enzyme Inhibitors; Humans; Models, Molecular; Neoplasms; Protein Tyrosine Phosphatase, Non-Receptor Type 11 | 2008 |
Heteroatom-substituted analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-Adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid.
Topics: Acrylates; Adamantane; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cinnamates; Drug Design; Humans; Leukemia, Myeloid, Acute; Ligands; Mice; Orphan Nuclear Receptors | 2011 |
Analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. 2. Impact of 3-chloro group replacement on inhibition of proliferation and induction of apoptosis of
Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cinnamates; Drug Screening Assays, Antitumor; Leukemia; Ligands; Mice; Models, Molecular; Neoplastic Stem Cells; Receptors, Cytoplasmic and Nuclear; Stem Cells; Stereoisomerism; Structure-Activity Relationship; Wnt1 Protein | 2012 |
ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis.
Topics: Adamantane; Antineoplastic Agents; Apoptosis; Calcium; Cell Line, Tumor; Chelating Agents; Cinnamates; Dihydropyridines; Egtazic Acid; Gene Expression; HeLa Cells; Homeostasis; Humans; Intracellular Fluid; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid; Mitochondria; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma; Retinoids | 2004 |
Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response.
Topics: Adamantane; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cinnamates; Cytochromes c; DNA; DNA Damage; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Activation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Histones; Humans; In Situ Nick-End Labeling; Membrane Potentials; Mitochondria; Phosphorylation; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2005 |
Induction of GDF-15/NAG-1/MIC-1 in human lung carcinoma cells by retinoid-related molecules and assessment of its role in apoptosis.
Topics: Adamantane; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Large Cell; Cinnamates; Cytokines; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; Humans; Lung Neoplasms; Oncogene Proteins, Viral; Poly(ADP-ribose) Polymerases; Repressor Proteins; Retinoids; RNA, Small Interfering; Tretinoin; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2006 |
Antitumor activity of the retinoid-related molecules (E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor gamm
Topics: Adamantane; Animals; Antineoplastic Agents; Calcium; Cell Death; Cell Differentiation; Cells, Cultured; Chlorocebus aethiops; Cinnamates; COS Cells; Cytosol; Disease Models, Animal; G2 Phase; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, SCID; Mitosis; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma; Retinoids; RNA, Messenger; Teratocarcinoma; Tretinoin | 2006 |
Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity.
Topics: Adamantane; Animals; Cell Death; Cell Line, Tumor; Cell Proliferation; CHO Cells; Chromosome Aberrations; Cinnamates; Cricetinae; Cricetulus; DNA Breaks, Double-Stranded; DNA Repair; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Activation; Histones; Humans; Phosphorylation; Protein Kinases; Recombination, Genetic; Retinoids; S Phase | 2008 |
A new class of synthetic retinoid antibiotics effective against bacterial persisters.
Topics: Animals; Anti-Bacterial Agents; Benzoates; Caenorhabditis elegans; Cell Death; Cell Line; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Gentamicins; Humans; Lipid Bilayers; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Molecular Dynamics Simulation; Mutation; Naphthols; Retinoids; Staphylococcal Infections | 2018 |