carbocyanines and lumin
carbocyanines has been researched along with lumin* in 1 studies
Other Studies
1 other study(ies) available for carbocyanines and lumin
| Article | Year |
|---|---|
Suppressive effects of a cyanine dye against herpes simplex virus (HSV)-1 infection.
In this study, we demonstrate that a cyanine dye, lumin, significantly suppressed cytopathic effect by herpes simplex virus (HSV)-1 toward human amnionic FL cell and also it reduced replication of HSV-1 in a dose-dependent manner. In addition, lumin additively augmented the antiviral effect of interferon (IFN)-alpha. Furthermore, fluorescence microscopic study showed that lumin (not IFN-alpha) itself remarkably induced alkalinization of intracellular organelle, suggesting the inhibition of virus invasion into the cells. These results suggest that lumin exerts an antiviral action against HSV-1 with the independent pathways of IFN-alpha and also it would become a therapeutically effective drug in clinical practice. Topics: Amniotic Fluid; Carbocyanines; Cell Line; Endosomes; Herpes Simplex; Herpesvirus 1, Human; Humans; Hydrogen-Ion Concentration; Interferon-alpha; Quinolinium Compounds; Virus Replication | 2009 |