caffeine and xanthine

caffeine has been researched along with xanthine in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.63)18.7374
1990's7 (16.28)18.2507
2000's12 (27.91)29.6817
2010's14 (32.56)24.3611
2020's5 (11.63)2.80

Authors

AuthorsStudies
Brufani, M; Cavallaro, RA; Filocamo, L; Galione, A; Galuppi, A; Genazzani, AA1
Bearne, SL; Lunn, FA; Roy, AC1
Fernández, JR; Firestein, BL; Sweet, ES; Welsh, WJ1
Mohamed, T; Osman, W; Rao, PP; Tin, G1
Gilboe, DP1
Hafkenscheid, JC; Hekster, YA; Nouws, JF; Vree, JB; Vree, TB1
Carney, JM; Logan, L; McMaster, SB; Seale, TW1
Charland, SL; Melko, GP; Stanek, EJ1
Inoue, I; Maeda, K; Miwa, M; Morita, H; Nakai, S; Odani, H; Shinzato, T1
Hindmarsh, KW; Kalapurackal, M; Sankaran, K; Tan, L1
Fay, LB; Richoz, J; Stadler, RH; Turesky, RJ; Welti, DH1
Goldhaber, JI1
Mazzafera, P; Vitória, AP1
Kurihara, T; Labádi, I; Miskolci, C; Molnár, J; Motohashi, N1
Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM1
Cameron, IL; Lyles, MB1
Azam, S; Hadi, N; Hadi, SM; Khan, NU1
BLAKE, M; HARRIS, LE1
FIRTH, A; SMITH, WG1
Ariniemi, K; Hietanen, H; Kanerva, H; Kekki, T; Lindevall, K; Lipponen, M; Marvola, J; Marvola, M; Mykkänen, S; Slot, L1
Anstis, M; Edwards, HG; Munshi, T1
Güçlü, V; Sağlam, A; Ucun, F1
Daly, JW1
Dekker, MJ; Graham, TE; Gusba, JE; Robinson, LE1
Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Yu, CL1
Lan, J; Lian, S; Wang, W; Yang, F; You, J; Zhao, D1
Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Summers, R; Yu, CL1
Farrokhpour, H; Fathi, F1
Coreno, M; Feyer, V; Moise, A; Moskovskaya, TE; Plekan, O; Prince, KC; Richter, R; Soshnikov, DY; Trofimov, AB; Zaytseva, IL1
John, SA; Raj, MA1
Alnahhas, RN; Bachman, JL; Barrick, JE; Dasgupta, A; Hammerling, MJ; Otoupal, PB; Quandt, EM; Slater, B; Subramanian, MV; Summers, RM1
Guo, H; Yue, Y1
Bertrand, B; Bodio, E; Casini, A; de Jager, MH; Groothuis, GM; Le Gendre, P; Monchaud, D; Picquet, M; Pirrotta, M; Richard, P; Stefan, L; Warmerdam, E1
Laing, T; Lake, BR; Mohamed, HA; Phillips, RM; Willans, CE1
Chang, DW; Eng, C; Hildebrandt, MAT; Kopetz, S; Liang, D; Lin, M; Long, Y; Mishra, L; Raju, GS; Sanchez-Espiridion, B; White, L; Wu, X; Ye, Y1
Dong, ZB; Liang, YR; Lu, J; Ma, YX; Wu, HS; Wu, XH; Ye, JH; Zheng, XQ1
Azzolin, VF; Barbisan, F; da Cruz Jung, IE; da Cruz, IBM; da Cunha, BSN; do Prado-Lima, PA; Duarte, MMMF; Duarte, T; Ribeiro, EE; Turra, BO1
Bell, TL; Carrasco-Cabrera, CP; Kertesz, MA1
Busch, M; D'Alessandro, A; Fu, X; Kanias, T; Kleinman, S; Page, GP; Reisz, JA; Stone, M; Zimring, JC1
Gowthaman, NSK; John, SA; Sinduja, B1
Liu, H; Wang, B; Xiong, L; Yang, N; Zhang, S1
Anitta, S; Meenakshi, S; Sekar, C; Sudhan, N1
Ahluwalia, BS; Cogger, VC; Cole, L; Diekmann, R; Holte, C; Kruse, L; Le Couteur, D; Lockwood, GP; Mao, H; McCourt, PAG; Szafranska, K; Whitchurch, CB; Wolfson, DL1

Reviews

2 review(s) available for caffeine and xanthine

ArticleYear
Xanthine interference with dipyridamole-thallium-201 myocardial imaging.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:4

    Topics: Adenosine; Animals; Caffeine; Coronary Disease; Dipyridamole; Dogs; False Negative Reactions; Heart; Humans; Male; Pentoxifylline; Radionuclide Imaging; Thallium Radioisotopes; Xanthine; Xanthines

1995
Caffeine analogs: biomedical impact.
    Cellular and molecular life sciences : CMLS, 2007, Volume: 64, Issue:16

    Topics: Alzheimer Disease; Asthma; Biomedical Research; Caffeine; Calcium; Central Nervous System Stimulants; Diabetes Mellitus; Diuretics; Humans; Inflammation; Lung Diseases; Mental Disorders; Molecular Structure; Neoplasms; Pain; Parkinson Disease; Phosphoric Diester Hydrolases; Protein Isoforms; Receptors, GABA-A; Receptors, Purinergic P1; Xanthine

2007

Trials

3 trial(s) available for caffeine and xanthine

ArticleYear
Role of adenosine in dialysis-induced hypotension.
    Journal of the American Society of Nephrology : JASN, 1994, Volume: 4, Issue:12

    Topics: Adenosine; Aged; Caffeine; Female; Humans; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Models, Biological; Norepinephrine; Renal Dialysis; Sympathetic Nervous System; Vascular Resistance; Vasodilation; Xanthine; Xanthines

1994
Neutron activation-based gamma scintigraphy in pharmacoscintigraphic evaluation of an Egalet constant-release drug delivery system.
    International journal of pharmaceutics, 2004, Aug-20, Volume: 281, Issue:1-2

    Topics: Adult; Area Under Curve; Biological Availability; Caffeine; Chemistry, Pharmaceutical; Delayed-Action Preparations; Gastrointestinal Tract; Humans; Male; Neutron Activation Analysis; Oxides; Radioisotopes; Radionuclide Imaging; Samarium; Xanthine

2004
Stored RBC metabolism as a function of caffeine levels.
    Transfusion, 2020, Volume: 60, Issue:6

    Topics: Adult; Blood Preservation; Caffeine; Coffee; Erythrocytes; Female; Glycolysis; Humans; Male; Metabolomics; Pentose Phosphate Pathway; Xanthine

2020

Other Studies

38 other study(ies) available for caffeine and xanthine

ArticleYear
Potentiation of cADPR-induced Ca(2+)-release by methylxanthine analogues.
    Journal of medicinal chemistry, 1999, Jul-15, Volume: 42, Issue:14

    Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cyclic ADP-Ribose; Drug Evaluation, Preclinical; In Vitro Techniques; Ovum; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Structure-Activity Relationship; Xanthines

1999
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines

2010
Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine.
    Bioorganic & medicinal chemistry, 2010, Sep-15, Volume: 18, Issue:18

    Topics: Binding Sites; Cognition Disorders; Energy Metabolism; Guanine; Guanine Deaminase; Humans; Kinetics; Ligands; Liver Diseases; Microtubules; Molecular Dynamics Simulation; Protein Binding; Small Molecule Libraries; Structure-Activity Relationship

2010
Selective inhibition of human acetylcholinesterase by xanthine derivatives: in vitro inhibition and molecular modeling investigations.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Caffeine; Catalytic Domain; Cholinesterase Inhibitors; Humans; Hydrogen Bonding; Molecular Docking Simulation; Pentoxifylline; Protein Binding; Thermodynamics; Xanthine; Xanthines

2013
The mechanism of caffeine-enhanced glucose stimulation of liver glycogen synthase phosphatase activity.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Drug Interactions; Glucose; Glucose-6-Phosphate; Glucosephosphates; Liver; Male; Phosphoprotein Phosphatases; Rats; Structure-Activity Relationship; Theobromine; Theophylline; Time Factors; Xanthine; Xanthines

1986
Excretion and metabolism of a series of xanthines by the turtle Pseudemys scripta elegans.
    The veterinary quarterly, 1989, Volume: 11, Issue:1

    Topics: Animals; Caffeine; Theobromine; Theophylline; Turtles; Uric Acid; Xanthine; Xanthines

1989
Sensitivity of inbred mice to methylxanthines is not determined by plasma xanthine concentration.
    Neuroscience letters, 1985, May-01, Volume: 56, Issue:1

    Topics: Animals; Body Temperature; Caffeine; Male; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Motor Activity; Species Specificity; Theophylline; Xanthine; Xanthines

1985
Plasma beta-endorphin concentration and xanthine treatment in apnea of prematurity.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1993, Volume: 16, Issue:3

    Topics: Apnea; beta-Endorphin; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Xanthine; Xanthines

1993
Oxidation of caffeine and related methylxanthines in ascorbate and polyphenol-driven Fenton-type oxidations.
    Free radical research, 1996, Volume: 24, Issue:3

    Topics: Animals; Ascorbic Acid; Caffeine; Catalase; Cattle; Chromatography, High Pressure Liquid; Edetic Acid; Ferrous Compounds; Hydroxyl Radical; Kinetics; Liver; Mass Spectrometry; Molecular Structure; Oxidation-Reduction; Phenols; Purines; Superoxide Dismutase; Xanthine; Xanthine Oxidase; Xanthines

1996
Free radicals enhance Na+/Ca2+ exchange in ventricular myocytes.
    The American journal of physiology, 1996, Volume: 271, Issue:3 Pt 2

    Topics: Animals; Caffeine; Calcium; Carrier Proteins; Heart Ventricles; Hydrogen Peroxide; Myocardium; Patch-Clamp Techniques; Rabbits; Reactive Oxygen Species; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Xanthine; Xanthine Oxidase; Xanthines

1996
Xanthine degradation and related enzyme activities in leaves and fruits of two coffea species differing in caffeine catabolism.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:5

    Topics: Caffeine; Coffee; Plant Leaves; Seeds; Species Specificity; Urate Oxidase; Xanthine; Xanthine Dehydrogenase

1999
Guanine-cytosine rich regions of plasmid DNA can be the target in anti-plasmid effect of phenothiazines.
    International journal of antimicrobial agents, 2000, Volume: 14, Issue:3

    Topics: Binding Sites; Caffeine; Cytosine; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Guanine; Guanosine Monophosphate; Phenothiazines; Plasmids; Xanthine

2000
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
    Teratogenesis, carcinogenesis, and mutagenesis, 2001, Volume: 21, Issue:2

    Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chromatography, Gas; Cytosol; Diet; Enzyme Inhibitors; Ethanol; Free Radicals; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Male; Meat; NAD; Neoplasms; Niacinamide; Phosphodiesterase Inhibitors; Prostate; Prostatic Neoplasms; Purines; Rats; Rats, Sprague-Dawley; Spin Trapping; Temperature; Theobromine; Theophylline; Time Factors; Vasodilator Agents; Xanthine; Xanthine Oxidase

2001
Caffeine and other xanthines as cytochemical blockers and removers of heterocyclic DNA intercalators from chromatin.
    Cell biology international, 2002, Volume: 26, Issue:2

    Topics: Acridine Orange; Aminophylline; Animals; Caffeine; Cell Nucleus; Central Nervous System Stimulants; Chick Embryo; Chromatin; Chromosomes; DNA; Fluorescent Dyes; Intercalating Agents; Kinetics; Microscopy, Fluorescence; Mutagens; Phosphodiesterase Inhibitors; Protein Binding; Spectrometry, Fluorescence; Time Factors; Uric Acid; Xanthine

2002
Antioxidant and prooxidant properties of caffeine, theobromine and xanthine.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:9

    Topics: Animals; Antioxidants; Caffeine; Cattle; Copper; DNA; DNA Damage; Hydroxyl Radical; Oxidants; Plasmids; Theobromine; Uric Acid; Xanthine

2003
The action of solubilizing agents on the solubility of xanthine derivatives in water. II. The application of conductimetric titrations to the study of xanthine combinations.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1952, Volume: 41, Issue:10

    Topics: Caffeine; Diuretics; Solubility; Theobromine; Theophylline; Water; Xanthine; Xanthines

1952
THE ANTI-ANAPHYLACTIC ACTIVITY OF THEOPHYLLINE AND SOME RELATED XANTHINE DERIVATIVES.
    The Journal of pharmacy and pharmacology, 1964, Volume: 16

    Topics: Anaphylaxis; Anti-Allergic Agents; Caffeine; Diuretics; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Lipids; Lung; Pharmacology; Research; Theobromine; Theophylline; Xanthine; Xanthines

1964
Raman spectroscopic characterisations and analytical discrimination between caffeine and demethylated analogues of pharmaceutical relevance.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 61, Issue:7

    Topics: Alkaloids; Caffeine; Models, Chemical; Spectroscopy, Fourier Transform Infrared; Theobromine; Theophylline; Xanthine

2005
Molecular structures and vibrational frequencies of xanthine and its methyl derivatives (caffeine and theobromine) by ab initio Hartree-Fock and density functional theory calculations.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2007, Volume: 67, Issue:2

    Topics: Caffeine; Mathematical Computing; Models, Chemical; Molecular Structure; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Theobromine; Vibration; Xanthine

2007
Glucose homeostasis remains altered by acute caffeine ingestion following 2 weeks of daily caffeine consumption in previously non-caffeine-consuming males.
    The British journal of nutrition, 2007, Volume: 98, Issue:3

    Topics: Administration, Oral; Blood Glucose; C-Peptide; Caffeine; Epinephrine; Fatty Acids, Nonesterified; Glucose; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Male; Xanthine

2007
A novel caffeine dehydrogenase in Pseudomonas sp. strain CBB1 oxidizes caffeine to trimethyluric acid.
    Journal of bacteriology, 2008, Volume: 190, Issue:2

    Topics: Bacterial Proteins; Caffeine; Oxidoreductases; Pseudomonas; Substrate Specificity; Theobromine; Ubiquinone; Uric Acid; Xanthine

2008
Phosphine-free, palladium-catalyzed arylation of heterocycles through C-H bond activation with pivalic acid as a cocatalyst.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2009, Volume: 15, Issue:6

    Topics: Azoles; Caffeine; Catalysis; Heterocyclic Compounds; Palladium; Pentanoic Acids; Toluene; Xanthine

2009
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
    Journal of bacteriology, 2009, Volume: 191, Issue:14

    Topics: Caffeine; Gene Expression; Metabolic Networks and Pathways; Pseudomonas putida; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines

2009
Theoretical study of valance photoelectron spectra of hypoxanthine, xanthine, and caffeine using direct symmetry-adapted cluster/configuration interaction methodology.
    Journal of computational chemistry, 2011, Volume: 32, Issue:11

    Topics: Caffeine; Computer Simulation; Hypoxanthine; Models, Molecular; Models, Theoretical; Photochemistry; Quantum Theory; Xanthine

2011
X-ray spectroscopy of heterocyclic biochemicals: xanthine, hypoxanthine, and caffeine.
    The journal of physical chemistry. A, 2012, Jun-14, Volume: 116, Issue:23

    Topics: Caffeine; Carbon; Gases; Hypoxanthine; Models, Chemical; Molecular Structure; Nitrogen; Oxygen; Quantum Theory; Spectrometry, X-Ray Emission; X-Ray Absorption Spectroscopy; Xanthine

2012
Simultaneous determination of uric acid, xanthine, hypoxanthine and caffeine in human blood serum and urine samples using electrochemically reduced graphene oxide modified electrode.
    Analytica chimica acta, 2013, Apr-10, Volume: 771

    Topics: Blood Chemical Analysis; Caffeine; Catalysis; Electrochemistry; Electrodes; Graphite; Humans; Hypoxanthine; Oxidation-Reduction; Oxides; Purines; Spectrum Analysis, Raman; Time Factors; Uric Acid; Urinalysis; Xanthine

2013
Decaffeination and measurement of caffeine content by addicted Escherichia coli with a refactored N-demethylation operon from Pseudomonas putida CBB5.
    ACS synthetic biology, 2013, Jun-21, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Beverages; Biosensing Techniques; Caffeine; Escherichia coli; Genome, Bacterial; Glutathione Transferase; Guanine; Methylation; Multigene Family; Operon; Plasmids; Pseudomonas putida; Xanthine; Xanthines

2013
Quantum mechanical/molecular mechanical study of catalytic mechanism and role of key residues in methylation reactions catalyzed by dimethylxanthine methyltransferase in caffeine biosynthesis.
    Journal of chemical information and modeling, 2014, Feb-24, Volume: 54, Issue:2

    Topics: Biocatalysis; Caffeine; Methylation; Methyltransferases; Models, Molecular; Protein Conformation; Quantum Theory; Thermodynamics; Xanthine

2014
Caffeine-based gold(I) N-heterocyclic carbenes as possible anticancer agents: synthesis and biological properties.
    Inorganic chemistry, 2014, Feb-17, Volume: 53, Issue:4

    Topics: Animals; Antineoplastic Agents; Caffeine; Cell Line; Cell Line, Tumor; Cell Proliferation; Gold; Heterocyclic Compounds; Humans; Inhibitory Concentration 50; Ligands; Methane; Molecular Structure; Xanthine

2014
Synthesis and anticancer activity of silver(I)-N-heterocyclic carbene complexes derived from the natural xanthine products caffeine, theophylline and theobromine.
    Dalton transactions (Cambridge, England : 2003), 2015, Apr-28, Volume: 44, Issue:16

    Topics: Antineoplastic Agents; Biological Products; Caffeine; Cell Line, Tumor; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Hydrophobic and Hydrophilic Interactions; Methane; Molecular Conformation; Silver; Theobromine; Theophylline; Xanthine

2015
Global and targeted serum metabolic profiling of colorectal cancer progression.
    Cancer, 2017, Oct-15, Volume: 123, Issue:20

    Topics: Adenoma; Adult; Aged; Caffeine; Case-Control Studies; Chromatography, Liquid; Colonic Polyps; Colorectal Neoplasms; Disease Progression; Female; Humans; Hypoxanthine; Intestinal Polyps; Logistic Models; Male; Mannose; Metabolomics; Middle Aged; Multivariate Analysis; Tandem Mass Spectrometry; Urea; Xanthine

2017
Different Catabolism Pathways Triggered by Various Methylxanthines in Caffeine-Tolerant Bacterium
    Journal of microbiology and biotechnology, 2018, Jul-28, Volume: 28, Issue:7

    Topics: Biodegradation, Environmental; Caffeine; Drug Tolerance; Gardens; Metabolic Networks and Pathways; Pseudomonas putida; Soil; Soil Microbiology; Substrate Specificity; Tea; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines

2018
The Influence of a Xanthine-Catechin Chemical Matrix on in vitro Macrophage-Activation Triggered by Antipsychotic Ziprasidone.
    Inflammation, 2019, Volume: 42, Issue:3

    Topics: Animals; Antipsychotic Agents; Caffeine; Catechin; Cell Proliferation; Complex Mixtures; Inflammation; Macrophage Activation; Macrophages; Mice; Oxidative Stress; Paullinia; Piperazines; RAW 264.7 Cells; Theobromine; Thiazoles; Xanthine

2019
Caffeine metabolism during cultivation of oyster mushroom (Pleurotus ostreatus) with spent coffee grounds.
    Applied microbiology and biotechnology, 2019, Volume: 103, Issue:14

    Topics: Caffeine; Coffee; Culture Media; Fruiting Bodies, Fungal; Industrial Microbiology; Industrial Waste; Mycelium; Pleurotus; Waste Products; Xanthine

2019
Fabrication of low-cost sustainable electrocatalyst: a diagnostic tool for multifunctional disorders in human fluids.
    Journal of materials chemistry. B, 2020, 10-28, Volume: 8, Issue:41

    Topics: Ascorbic Acid; Biosensing Techniques; Caffeine; Carbon; Catalysis; Electrochemical Techniques; Electrodes; Female; Humans; Hypoxanthine; Male; Uric Acid; Xanthine

2020
Synthesis and evaluation of novel xanthine-acrylamides and xanthine-acrylates as insecticidal agents.
    Pest management science, 2022, Volume: 78, Issue:5

    Topics: Acrylamides; Animals; Caffeine; Insecticides; Larva; Molecular Structure; Moths; Pesticides; Structure-Activity Relationship; Xanthine

2022
Brushite nanoparticles based electrochemical sensor for detection of uric acid, xanthine, hypoxanthine and caffeine.
    Analytical biochemistry, 2022, 12-15, Volume: 659

    Topics: Ascorbic Acid; Caffeine; Electrochemical Techniques; Electrodes; Humans; Hypoxanthine; Nanoparticles; Uric Acid; Xanthine

2022
Effect of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure.
    Scientific reports, 2023, 08-17, Volume: 13, Issue:1

    Topics: Animals; Caffeine; Endothelial Cells; Liver; Rats; Theobromine; Xanthine

2023