caffeine and naloxone
caffeine has been researched along with naloxone in 55 studies
Research
Studies (55)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (38.18) | 18.7374 |
| 1990's | 9 (16.36) | 18.2507 |
| 2000's | 12 (21.82) | 29.6817 |
| 2010's | 12 (21.82) | 24.3611 |
| 2020's | 1 (1.82) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Collier, HO; Francis, DL; Roy, AC | 1 |
| Aceto, MD; Carchman, RA; Flora, RE; Harris, LS | 1 |
| Butt, NM; Collier, HO; Cuthbert, NJ; Francis, DL; Saeed, SA | 1 |
| Durcan, MJ; Morgan, PF | 1 |
| Campus, MP; Capogrossi, MC; Lakatta, EG; Sisini, A; Ventura, C | 1 |
| Kuribara, H; Tadokoro, S | 1 |
| Contreras, E; Germany, A; Villar, M | 1 |
| DeLander, GE; Hopkins, CJ | 1 |
| Adamson, P; Brammer, MJ; Campbell, IC; Hajimohammadreza, I; Mantzouridis, T; Xiang, JZ | 1 |
| Frank, GB; Kokate, TG | 1 |
| Ahlijanian, MK; Takemori, AE | 1 |
| Henry, JL; Salter, MW | 1 |
| Kaschube, M; Strubelt, O; Zetler, G | 1 |
| Koob, GF; Swerdlow, NR; Vaccarino, FJ | 1 |
| Gorodetzky, CW; Kullberg, MP | 1 |
| Levine, AS; Morley, JE; Wager-Srdar, S | 1 |
| Ammon, HP | 1 |
| Eaves, M; Koob, GF; Rivier, J; Seeligson, M; Sutton, R; Swerdlow, N; Vale, W | 1 |
| Collier, HO; Cuthbert, NJ; Francis, DL | 1 |
| Arnold, MA; Carr, DB; Martin, JB; Pian, MC; Togasaki, DM | 1 |
| Iverson, LL | 1 |
| Devoize, JL; Eschalier, A; Renoux, M; Rigal, F; Trolese, JF | 1 |
| Waite, E; Wang, RI | 1 |
| Contreras, E; Juica, S; Tamayo, L | 1 |
| Erickson, CK | 1 |
| Holtzman, SG; Jones, DN | 1 |
| Begnini, J; Bellot, RG; De-La-Vega, DD; Frussa-Filho, R; Jimenez-Bernal, RE; Lopes, FP; Mello, CF; Schwartz, CC | 1 |
| Akimoto, T; Mashimoto, S; Suetsugi, M; Ushijima, I; Watanabe, K; Yamada, M | 1 |
| Adams, DJ; Smith, AB | 1 |
| Capasso, A | 1 |
| Dixon, AK; Freeman, TC; Lee, K; Preston, Z; Richardson, PJ; Widdowson, L | 1 |
| Fogle, CM; Mayorga, AJ; Paule, MG; Popke, EJ | 1 |
| Bezard, E; Bilbao, A; Chen, JF; Cippitelli, A; Granado, N; Martín, AB; Moratalla, R; Navarro, M; Ortiz, O; Rodríguez de Fonseca, F | 1 |
| Capasso, A; Gallo, C | 1 |
| Bhanumathy, M; Chandrasekar, SB; Divakar, K; Goli, D; Harisha, R; Pawar, AT; Shivaprasad, HN; Sushma, G | 1 |
| Habib, M; Waheed, I | 1 |
| Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J | 1 |
| Carrillo-Munguía, N; Díaz-Reval, MI; González-Trujano, ME; Huerta, M; Trujillo, X | 1 |
| Caumo, W; Dos Santos, ARS; Martins, DF; Martins, TC; Medeiros, LF; Nucci-Martins, C; Siteneski, A; Souza, A; Torres, ILS | 1 |
| Beardsley, PM; Elder, HJ; Walentiny, DM | 1 |
Reviews
2 review(s) available for caffeine and naloxone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[New aspects of the mechanism of the central nervous system stimulating effect of caffeine].
Topics: Adenosine; Aminobutyrates; Animals; Brain; Caffeine; Calcium; Cyclic AMP; Habituation, Psychophysiologic; Humans; Mice; Naloxone; Phosphodiesterase Inhibitors; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Opioid; Receptors, Purinergic; Xanthines | 1984 |
Trials
1 trial(s) available for caffeine and naloxone
| Article | Year |
|---|---|
Crossover and parallel study of oral analgesics.
Topics: Administration, Oral; Adult; Aged; Analgesics; Analysis of Variance; Aspirin; Caffeine; Clinical Trials as Topic; Dextropropoxyphene; Drug Combinations; Humans; Middle Aged; Naloxone; Oxycodone; Phenacetin | 1981 |
Other Studies
52 other study(ies) available for caffeine and naloxone
| Article | Year |
|---|---|
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Morphone abstinence and quasi-abstinence effects after phosphodiesterase inhibitors and naloxone.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Male; Morphine; Naloxone; Phosphodiesterase Inhibitors; Prostaglandins; Rats; Structure-Activity Relationship; Substance Withdrawal Syndrome; Theophylline; Time Factors; Xanthines | 1975 |
Caffeine elicited withdrawal signs in morphine-dependent rhesus monkeys.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Behavior, Animal; Benzoates; Brain; Caffeine; Conditioning, Operant; Female; Haplorhini; Humans; Macaca mulatta; Male; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome | 1978 |
Mechanism of quasi-morphine withdrawal behaviour induced by methylxanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Humans; Male; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Theobromine; Theophylline; Xanthines | 1979 |
Opioid receptor mediation of the hypothermic response to caffeine.
Topics: Animals; Body Temperature; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Male; Metergoline; Mice; Naloxone; Receptors, Opioid; Sympatholytics | 1992 |
Leucine-enkephalin increases the level of inositol (1,4,5) triphosphate and releases calcium from an intracellular pool in rat ventricular cardiac myocytes.
Topics: Animals; Caffeine; Calcium; Enkephalin, Leucine; Heart; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Myocardium; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Ryanodine; Sarcoplasmic Reticulum; Second Messenger Systems | 1991 |
The ambulation-increasing effect of buprenorphine in mice: comparison with the effect of morphine.
Topics: Animals; Buprenorphine; Caffeine; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Locomotion; Male; Methamphetamine; Mice; Morphine; Naloxone; Pilocarpine; Scopolamine | 1991 |
Effects of some adenosine analogs on morphine-induced analgesia and tolerance.
Topics: 2-Chloroadenosine; Adenosine; Analgesics; Animals; Caffeine; Drug Synergism; Drug Tolerance; Injections, Intraventricular; Mice; Morphine; Naloxone; Phenylisopropyladenosine | 1990 |
Spinal adenosine modulates descending antinociceptive pathways stimulated by morphine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Analgesia; Animals; Caffeine; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Nociceptors; Spinal Cord; Theophylline; Xanthines | 1986 |
Alpha 2-adrenergic, kappa-opiate, and P1-purinergic autoreceptors have mutually antagonistic effects: a new regulatory mechanism?
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzofurans; Caffeine; Calcium; Cerebral Cortex; Clonidine; Dioxanes; Fluorescent Dyes; Fura-2; Homeostasis; Idazoxan; Male; Naloxone; Phenylisopropyladenosine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Purinergic; Synaptosomes | 1989 |
Blockade of K+ contractures in skeletal muscle by opioid drugs: a nonstereospecific effect.
Topics: Animals; Caffeine; In Vitro Techniques; Isometric Contraction; Muscles; Naloxone; Narcotics; Neuromuscular Depolarizing Agents; Potassium; Rana pipiens; Stereoisomerism | 1989 |
The effect of chronic administration of caffeine on morphine-induced analgesia, tolerance and dependence in mice.
Topics: Analgesia; Animals; Caffeine; Drug Interactions; Drug Tolerance; Male; Mice; Morphine; Morphine Dependence; Naloxone; Phenylisopropyladenosine; Reaction Time; Receptors, Opioid | 1986 |
Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat.
Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Caffeine; Cats; Dipyridamole; Injections, Intravenous; Iontophoresis; Naloxone; Neurons; Spinal Cord; Strychnine; Theophylline; Vibration | 1987 |
Failure of coffee to inhibit the pharmacodynamic activity of morphine in vivo.
Topics: Analgesia; Animals; Blood Pressure; Caffeine; Coffee; Guinea Pigs; Heart Rate; Male; Mice; Morphine; Muscle, Smooth; Naloxone; Rats; Rats, Inbred Strains; Respiration | 1986 |
Effects of naloxone on heroin-, amphetamine- and caffeine-stimulated locomotor activity in the rat.
Topics: Amphetamine; Animals; Caffeine; Heroin; Male; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cocaine; Codeine; Evaluation Studies as Topic; Glucuronates; Humans; Hydrolysis; Meperidine; Meprobamate; Mescaline; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Naloxone; Pentobarbital; Secobarbital; Substance-Related Disorders | 1974 |
Food intake: opioid/purine interactions.
Topics: Animals; Butorphanol; Caffeine; Cyclazocine; Drug Interactions; Endorphins; Ethylketocyclazocine; Feeding Behavior; Male; Naloxone; Purines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Effects of alpha-flupenthixol and naloxone on CRF-induced locomotor activation.
Topics: Animals; Arousal; Brain; Caffeine; Corticotropin-Releasing Hormone; Dextroamphetamine; Dose-Response Relationship, Drug; Flupenthixol; Injections, Intraventricular; Male; Motor Activity; Naloxone; Premedication; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Thioxanthenes | 1984 |
Character and meaning of quasi-morphine withdrawal phenomena elicited by methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Humans; Hypoxanthines; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Phosphodiesterase Inhibitors; Pyrimidines; Rats; Substance Withdrawal Syndrome; Theobromine; Theophylline; Triazoles; Xanthines | 1981 |
Caffeine stimulates beta-endorphin release in blood but not in cerebrospinal fluid.
Topics: Animals; beta-Endorphin; Caffeine; Endorphins; Kinetics; Male; Naloxone; Prolactin; Rats; Rats, Inbred Strains | 1982 |
Coffee and opiate receptors. Another cup of coffee?
Topics: Adenosine; Animals; Caffeine; Coffee; Guinea Pigs; Humans; Naloxone; Receptors, Cell Surface; Receptors, Opioid; Receptors, Purinergic | 1983 |
Influence of naloxone on antidepressant drug effects in the forced swimming test in mice.
Topics: Animals; Antidepressive Agents; Atropine; Behavior, Animal; Caffeine; Drug Interactions; Male; Mice; Naloxone; Physical Exertion; Restraint, Physical; Swimming | 1984 |
Sensitivity changes after morphine treatment in the mouse uterus.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Drug Tolerance; Female; In Vitro Techniques; Mice; Morphine; Naloxone; Serotonin; Theophylline; Uterine Contraction | 1982 |
Requirements for an ideal alcohol antagonist.
Topics: Alcoholic Intoxication; Animals; Caffeine; Cats; Dextroamphetamine; Disease Models, Animal; Dogs; Ethanol; gamma-Aminobutyric Acid; Humans; Maleates; Naloxone; Pentylenetetrazole; Rabbits; Strychnine | 1980 |
Influence of naloxone upon motor activity induced by psychomotor stimulant drugs.
Topics: Animals; Apomorphine; Caffeine; Catecholamines; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Male; Motor Activity; Naloxone; Neurotransmitter Uptake Inhibitors; Rats; Rats, Sprague-Dawley; Scopolamine | 1994 |
Antinociceptive effect of purine nucleotides.
Topics: Analgesics; Animals; Caffeine; Male; Mice; Naloxone; Narcotic Antagonists; Nociceptors; Purine Nucleotides; Quinidine; Receptors, Purinergic P1; Receptors, Purinergic P2; Rosaniline Dyes; Suramin; Theophylline | 1996 |
Stress-dependent antinociceptive effects of carbamazepine: a study in stressed and nonstressed rats.
Topics: Adenosine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Caffeine; Carbamazepine; Cerebral Ventricles; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Male; Naloxone; Pain; Physical Stimulation; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Time Factors | 1998 |
Met-enkephalin-induced mobilization of intracellular Ca2+ in rat intracardiac ganglion neurones.
Topics: Animals; Biological Transport; Caffeine; Calcium; Charybdotoxin; Electrophysiology; Enkephalin, Methionine; Ganglia; Heart Conduction System; Intracellular Membranes; Naloxone; Neurons; Potassium Channel Blockers; Potassium Channels; Rats; Ryanodine | 1999 |
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence.
Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2000 |
Adenosine receptor expression and function in rat striatal cholinergic interneurons.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Baclofen; Bicuculline; Caffeine; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; GABA Antagonists; Gene Expression; Male; Membrane Potentials; Naloxone; Narcotic Antagonists; Neurons; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Tritium; Xanthines | 2000 |
Comparison of drug effects on the performance of two timing tasks in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pentobarbital; Physostigmine; Rats; Rats, Sprague-Dawley; Task Performance and Analysis; Time Factors | 2000 |
Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice.
Topics: Adenosine A2 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Corpus Striatum; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Exploratory Behavior; Male; Mice; Mice, Knockout; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Receptor, Adenosine A2A; Receptors, Opioid, mu; RNA, Messenger; Substance Withdrawal Syndrome | 2006 |
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2009 |
Involvement of opioid, adenosine and 5-HT(3) receptors in antinociceptive effects of an ayurvedic polyherbal formulation.
Topics: Analgesics; Analgesics, Opioid; Animals; Caffeine; Drug Combinations; Medicine, Ayurvedic; Meperidine; Mice; Naloxone; Narcotic Antagonists; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Purinergic P1; Receptors, Serotonin, 5-HT3; Tail | 2011 |
Evaluation of anti-nociceptive, anti-inflammatory and antipyretic activities of Artemisia scoparia hydromethanolic extract.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Artemisia; Caffeine; Carrageenan; Edema; Female; Fever; Herb-Drug Interactions; Male; Methanol; Mice; Mice, Inbred BALB C; Naloxone; Pain; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Sodium Glutamate | 2013 |
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines | 2013 |
Tramadol and Tramadol+Caffeine Synergism in the Rat Formalin Test Are Mediated by Central Opioid and Serotonergic Mechanisms.
Topics: Analgesics, Opioid; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Ketanserin; Naloxone; Ondansetron; Pain; Pain Measurement; Rats; Tramadol | 2015 |
Neurobiological mechanisms of antiallodynic effect of transcranial direct current stimulation (tDCS) in a mice model of neuropathic pain.
Topics: Adenosine A1 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Flumazenil; GABA Modulators; Hyperalgesia; Male; Mice; Morpholines; Naloxone; Narcotic Antagonists; Neuralgia; Pain Threshold; Physical Stimulation; Pyrazoles; Transcranial Direct Current Stimulation; Xanthines | 2018 |
Theophylline reverses oxycodone's but not fentanyl's respiratory depression in mice while caffeine is ineffective against both opioids.
Topics: Analgesics, Opioid; Animals; Caffeine; Fentanyl; Male; Mice; Naloxone; Narcotic Antagonists; Oxycodone; Respiratory Insufficiency; Theophylline | 2023 |