caffeine has been researched along with mannitol in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (18.18) | 18.7374 |
| 1990's | 5 (15.15) | 18.2507 |
| 2000's | 12 (36.36) | 29.6817 |
| 2010's | 10 (30.30) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kehoe, J | 1 |
| Bruton, JD | 1 |
| Pietras, RJ; Wright, EM | 1 |
| Bull, AB; Harrison, GG | 1 |
| Drevius, LO | 1 |
| Gantt, R; Jones, GM; Parshad, R; Sanford, KK; Tarone, RE | 1 |
| Jones, GM; Parshad, R; Sanford, KK; Tarone, RE | 1 |
| Daniels, S; Duncan, CJ | 1 |
| Duncan, CJ; Morton, JW | 1 |
| Beuckmann, CT; Franke, H; Galla, HJ | 1 |
| Chessic, K; Liang, E; Yazdanian, M | 1 |
| Artusi, M; Colombo, P; Sacchetti, C; Santi, P | 1 |
| KURODA, K | 1 |
| Brown, MB; Forbes, B; Jones, SA; Khengar, RH; Turner, RB | 1 |
| Bock, U; Diembeck, W; Düsing, HJ; Gamer, A; Haltner-Ukomadu, E; Hoffmann, C; Kaca, M; Kamp, H; Kersen, S; Kietzmann, M; Korting, HC; Krächter, HU; Lehr, CM; Liebsch, M; Mehling, A; Müller-Goymann, C; Netzlaff, F; Niedorf, F; Rübbelke, MK; Schäfer, U; Schäfer-Korting, M; Schmidt, E; Schreiber, S; Spielmann, H; Vuia, A; Weimer, M | 1 |
| Heine, RJ; Meeuse, JC; Olthof, MR; Seebus, E; van Dam, RM; van Dijk, AE | 1 |
| Kholova, D; Kvetina, J; Smetana, J; Smetanova, L; Stetinova, V; Svoboda, Z | 1 |
| Karadzovska, D; Riviere, JE | 1 |
| Karadzovska, D; Riviere, J | 1 |
| Jacobsen, J; Marxen, E; Mosgaard, MD; Pedersen, AML | 1 |
| Hansen, SE; Jacobsen, J; Janfelt, C; Marxen, E | 1 |
1 review(s) available for caffeine and mannitol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for caffeine and mannitol
| Article | Year |
|---|---|
Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance.
Topics: Alkaloids; Blood Glucose; Caffeine; Chlorogenic Acid; Coffee; Cross-Over Studies; Glucose Tolerance Test; Humans; Insulin; Male; Mannitol; Overweight; Placebos | 2009 |
31 other study(ies) available for caffeine and mannitol
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Cyclic AMP-induced slow inward current in depolarized neurons of Aplysia californica.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aplysia; Caffeine; Calcium; Cyclic AMP; Electric Conductivity; Ganglia; Ion Channels; Magnesium; Mannitol; Meglumine; Membrane Potentials; Neurons; Phosphodiesterase Inhibitors; Potassium; Protein Kinase Inhibitors; Sodium; Tetraethylammonium; Tetraethylammonium Compounds | 1990 |
Contraction of rat soleus muscle and the effects of hypertonic treatments.
Topics: Animals; Caffeine; Female; Hypertonic Solutions; In Vitro Techniques; Mannitol; Membrane Potentials; Muscle Contraction; Potassium; Rats; Sucrose; Urea | 1991 |
Routes of nonelectrolyte permeation across epithelial membranes.
Topics: Acetamides; Alcohols; Animals; Antipyrine; Bufo marinus; Caffeine; Choroid Plexus; Epithelium; Erythritol; Gallbladder; Glycerol; Kinetics; Mannitol; Mathematics; Membranes; Niacinamide; Organ Specificity; Permeability; Rabbits; Rana catesbeiana; Sucrose; Urea; Urinary Bladder; Water | 1974 |
Recent advances in the understanding of anaesthetic-induced malignant hyperpyrexia.
Topics: Acidosis; Anesthetics; Animals; Anura; Bicarbonates; Caffeine; Calcium; Cold Temperature; Disease Models, Animal; Electrolytes; Enzymes; Halothane; Malignant Hyperthermia; Mannitol; Muscles; Procaine; Rats; Sarcoplasmic Reticulum; Succinylcholine; Swine; Tromethamine | 1973 |
The permeability of bull spermatozoa to water, polyhydric alcohols and univalent anions and the effects of the anions upon the kinetic activity of spermatozoa and sperm models.
Topics: Alcohols; Animals; Bromides; Caffeine; Cattle; Cell Membrane Permeability; Cell Movement; Chlorides; Erythritol; Fluorides; Iodides; Isotonic Solutions; Male; Mannitol; Models, Biological; Nitrates; Quaternary Ammonium Compounds; Sorbitol; Spermatozoa; Thiocyanates; Water | 1972 |
Repair of chromosome damage induced by X-irradiation during G2 phase in a line of normal human fibroblasts and its malignant derivative.
Topics: 4-Nitroquinoline-1-oxide; Caffeine; Catalase; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cytarabine; DNA Repair; Fibroblasts; Humans; Interphase; Mannitol; Radiation Dosage | 1982 |
Neoplastic transformation of human cells in culture associated with deficient repair of light-induced chromosomal DNA damage.
Topics: Caffeine; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Chromatids; DNA Repair; Humans; Light; Mannitol; Neoplasms | 1982 |
Are oxygen radicals implicated in the calcium paradox of the rat heart?
Topics: Animals; Caffeine; Calcium; Catalase; Creatine Kinase; Deferoxamine; Dinitrophenols; Free Radical Scavengers; Free Radicals; In Vitro Techniques; Mannitol; Myocardial Reperfusion Injury; Myocardium; Oxygen; Rats; Rats, Wistar; Superoxide Dismutase; Thiourea; Vitamin E | 1994 |
Effect of osmotic pressure on cellular damage in the perfused rat kidney.
Topics: Animals; Caffeine; Calcium; In Vitro Techniques; Kidney; L-Lactate Dehydrogenase; Mannitol; Osmotic Pressure; Perfusion; Rats; Rats, Wistar; Regression Analysis; Reperfusion Injury; Sarcolemma | 1994 |
An improved low-permeability in vitro-model of the blood-brain barrier: transport studies on retinoids, sucrose, haloperidol, caffeine and mannitol.
Topics: Animals; Blood-Brain Barrier; Caffeine; Cells, Cultured; Colchicine; Culture Media, Serum-Free; Endothelium, Vascular; Haloperidol; Mannitol; Retinoids; Sucrose; Swine | 1999 |
Evaluation of an accelerated Caco-2 cell permeability model.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Caco-2 Cells; Caffeine; Cell Membrane Permeability; Central Nervous System Stimulants; Diuretics, Osmotic; Electric Conductivity; Epithelial Cells; Humans; Hydrostatic Pressure; Mannitol; Microscopy, Electron; Microscopy, Electron, Scanning; Pharmaceutical Preparations | 2000 |
Caffeine microparticles for nasal administration obtained by spray drying.
Topics: Administration, Intranasal; Caffeine; Central Nervous System Stimulants; Drug Compounding; Excipients; Lactose; Mannitol; Methylcellulose; Microscopy, Electron, Scanning; Microspheres; Oxazines; Particle Size; Pharmaceutical Vehicles; Polyethylene Glycols; Powders | 2002 |
[Studies on the hygroscopicity of water-soluble, crystalline drugs. VIII].
Topics: Benzoates; Borates; Caffeine; Mannitol; Water; Wettability | 1963 |
Nail swelling as a pre-formulation screen for the selection and optimisation of ungual penetration enhancers.
Topics: Administration, Topical; Adult; Animals; Caffeine; Carbon Radioisotopes; Chemistry, Pharmaceutical; Diffusion Chambers, Culture; Drug Compounding; Drug Evaluation, Preclinical; Hoof and Claw; Horses; Humans; Hydrogen Peroxide; Kinetics; Mannitol; Middle Aged; Nails; Organ Size; Permeability; Pharmaceutical Vehicles; Reproducibility of Results; Thioglycolates; Urea; Water | 2007 |
The use of reconstructed human epidermis for skin absorption testing: Results of the validation study.
Topics: Animal Testing Alternatives; Animals; Caffeine; Epidermis; Flufenamic Acid; Humans; Ivermectin; Mannitol; Organ Culture Techniques; Plastic Surgery Procedures; Reproducibility of Results; Skin Absorption; Skin Irritancy Tests; Swine | 2008 |
Caco-2 cells and Biopharmaceutics Classification System (BCS) for prediction of transepithelial transport of xenobiotics (model drug: caffeine).
Topics: Biological Transport; Caco-2 Cells; Caffeine; Cell Culture Techniques; Cell Survival; Diffusion; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Kinetics; Linear Models; Mannitol; Permeability; Tight Junctions; Xenobiotics | 2009 |
Assessing vehicle effects on skin absorption using artificial membrane assays.
Topics: Animals; Biological Assay; Caffeine; Cortisone; Diclofenac; Ethanol; In Vitro Techniques; Mannitol; Membranes, Artificial; Propylene Glycol; Quantitative Structure-Activity Relationship; Salicylic Acid; Skin; Skin Absorption; Swine; Testosterone; Water | 2013 |
Assessing vehicle effects on skin absorption of non-volatile compounds using membrane-coated fiber arrays.
Topics: Acrylic Resins; Caffeine; Cortisone; Diclofenac; Dimethylpolysiloxanes; Ethanol; Mannitol; Membranes, Artificial; Polyethylene Glycols; Salicylic Acid; Skin Absorption; Testosterone; Volatilization; Water | 2013 |
Mucin dispersions as a model for the oromucosal mucus layer in in vitro and ex vivo buccal permeability studies of small molecules.
Topics: Caffeine; Cell Line; Diffusion; Epithelium; Gastric Mucins; Humans; Mannitol; Mouth Mucosa; Mucus; Nicotine; Permeability; Propranolol; Small Molecule Libraries | 2017 |
Buccal delivery of small molecules - Impact of levulinic acid, oleic acid, sodium dodecyl sulfate and hypotonicity on ex vivo permeability and spatial distribution in mucosa.
Topics: Administration, Buccal; Animals; Caffeine; Diazepam; Epithelium; Levulinic Acids; Lipids; Mannitol; Micelles; Mouth Mucosa; Oleic Acid; Osmolar Concentration; Permeability; Propylene Glycol; Small Molecule Libraries; Sodium Dodecyl Sulfate; Swine | 2018 |