caffeine and doxapram

caffeine has been researched along with doxapram in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199010 (33.33)18.7374
1990's5 (16.67)18.2507
2000's7 (23.33)29.6817
2010's4 (13.33)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cohn, M; Cohn, ML; Kraynack, BJ; Taylor, FH1
Bonora, M; Gautier, H; Milic-Emili, J; Siafakas, NM1
Day, MA; Neims, AH; Piercy, WN; Williams, RL1
Aranda, JV; Bairam, A; Blanchard, PW; Bureau, MA; Cote, A; Laudignon, N1
Irani, AJ; Merchant, RH1
Boyet, S; Nehlig, A; Schroeder, H1
Jauchem, JR1
Bairam, A; Vert, P1
Winnie, AP1
DaVanzo, JP; Kang, LS; Kline, ES; Ward, JW; Watterson, JR1
Bonora, M; Gautier, H1
Chernick, V; Ioffe, S; Jansen, AH1
Huon, C; Moriette, G; Mussat, P; Parat, S; Relier, JP1
Huon, C; Moriette, G; Mussat, P; Parat, S; Rey, E1
Bohnhorst, B; Darraj, S; Poets, CF1
Bhatia, J1
Barbé, F; Boutroy, MJ; Fresson, J; Hascoët, JM; Maillard, C1
Bhatt-Mehta, V; Schumacher, RE1
Bury, G; Charles, B; Charlton, M; Flenady, V; Fraser, S; Gray, PH; Hegarty, J; Henderson-Smart, D; Horton, L; Jacklin, R; Reid, S; Rogers, Y; Shearman, A; Steer, P; Walsh, A1
Gaugler, C; Marlier, L; Messer, J1
Giguère, S; Robertson, SA; Sanchez, LC; Shih, A; Szabo, NJ; Womble, AY1
Onland, W; Ten Hove, CH; van Kaam, AH; Vliegenthart, RJ1
Engbers, AGJ; Flint, RB; Knibbe, CAJ; Koch, BCP; Poets, CF; Reiss, IKM; Simons, SHP; Völler, S1
Koch, G; van den Anker, JN1
Allegaert, K; Carkeek, K; Cassart, V; Cornette, L; de Boode, WP; de Kort, EHM; Dijk, PH; Flint, RB; Hemels, MAC; Hermans, I; Hutten, GJ; Hütten, MC; Kelen, D; Kroon, AA; Lacaze-Masmonteil, T; Lefevere, J; Nuytemans, DH; Onland, W; Pas, ABT; Plaskie, K; Poley, MJ; Poppe, JA; Reiss, IKM; Simons, SHP; Smits, A; Stewart, B; Storm, KK; van Kaam, AH; van Weissenbruch, MM; Voeten, M; Willemsen, SP; Williams, O; Zonnenberg, IA1
Avdic, E; Bruschettini, M; Evans, S; Fiander, M; Pessano, S; Soll, R1

Reviews

7 review(s) available for caffeine and doxapram

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacotherapy of neonatal apnea.
    Indian pediatrics, 1991, Volume: 28, Issue:11

    Topics: Apnea; Caffeine; Citrates; Doxapram; Drug Combinations; Humans; Infant, Newborn; Theophylline

1991
Effects of drugs on thermal responses to microwaves.
    General pharmacology, 1985, Volume: 16, Issue:4

    Topics: Adrenergic beta-Antagonists; Analgesics; Anesthetics; Animals; Bemegride; Body Temperature; Caffeine; Cardiac Glycosides; Chlorpromazine; Cholinesterase Inhibitors; Doxapram; Glucocorticoids; Hexamethonium; Hexamethonium Compounds; Microwaves; Nicotine; Nikethamide; Parasympatholytics; Parasympathomimetics; Pentylenetetrazole; Serotonin; Sympathomimetics; Vitamins

1985
Current options in the management of apnea of prematurity.
    Clinical pediatrics, 2000, Volume: 39, Issue:6

    Topics: Apnea; Caffeine; Central Nervous System Stimulants; Doxapram; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline; Xanthines

2000
Treatment of apnea of prematurity.
    Paediatric drugs, 2003, Volume: 5, Issue:3

    Topics: Aminophylline; Apnea; Caffeine; Clinical Trials as Topic; Doxapram; Humans; Infant, Newborn; Infant, Premature; Respiratory System Agents; Theophylline

2003
Doxapram Treatment for Apnea of Prematurity: A Systematic Review.
    Neonatology, 2017, Volume: 111, Issue:2

    Topics: Apnea; Caffeine; Doxapram; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Respiratory System Agents; Theophylline

2017
Doxapram for the prevention and treatment of apnea in preterm infants.
    The Cochrane database of systematic reviews, 2023, 10-25, Volume: 10

    Topics: Aminophylline; Apnea; Caffeine; Doxapram; Humans; Infant, Newborn; Infant, Premature; Lung Diseases

2023

Trials

9 trial(s) available for caffeine and doxapram

ArticleYear
Chemical respirogenesis: a comparative study.
    Acta anaesthesiologica Scandinavica. Supplementum, 1973, Volume: 51

    Topics: Adult; Aminobutyrates; Aminophylline; Bemegride; Benzamides; Blood Pressure; Caffeine; Central Nervous System Stimulants; Doxapram; Female; Humans; Lobeline; Methylphenidate; Nikethamide; Pentylenetetrazole; Placebos; Pulse; Quinolizines; Respiration; Respiratory Tract Diseases; Spirometry

1973
Use of preestablished criteria for deciding on extubation in the very low birthweight newborn. Preliminary analysis of a randomized study.
    Biology of the neonate, 1993, Volume: 63, Issue:2

    Topics: Caffeine; Double-Blind Method; Doxapram; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Oxygen Inhalation Therapy; Prospective Studies; Respiration, Artificial; Retrospective Studies; Time Factors

1993
Low-dose doxapram for treatment of apnoea following early weaning in very low birthweight infants: a randomized, double-blind study.
    Acta paediatrica (Oslo, Norway : 1992), 1998, Volume: 87, Issue:11

    Topics: Apnea; Blood Pressure; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Doxapram; Humans; Infant, Newborn; Infant, Very Low Birth Weight; Infusions, Intravenous; Respiratory System Agents; Treatment Outcome; Ventilator Weaning

1998
Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants.
    Biology of the neonate, 1999, Volume: 76, Issue:4

    Topics: Apnea; Birth Weight; Bradycardia; Caffeine; Doxapram; Drug Resistance; Gestational Age; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infusions, Intravenous; Intubation, Gastrointestinal; Oxygen; Respiratory System Agents

1999
QT interval lengthening in premature infants treated with doxapram.
    Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:6

    Topics: Caffeine; Central Nervous System Stimulants; Doxapram; Drug Interactions; Female; Gestational Age; Hemodynamics; Humans; Infant, Newborn; Infant, Premature; Long QT Syndrome; Male

2001
High dose caffeine citrate for extubation of preterm infants: a randomised controlled trial.
    Archives of disease in childhood. Fetal and neonatal edition, 2004, Volume: 89, Issue:6

    Topics: Caffeine; Citrates; Double-Blind Method; Doxapram; Drug Combinations; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Male; Respiration, Artificial; Respiratory System Agents; Time Factors; Treatment Outcome; Ventilator Weaning

2004
Olfactory stimulation prevents apnea in premature newborns.
    Pediatrics, 2005, Volume: 115, Issue:1

    Topics: Apnea; Aromatherapy; Bradycardia; Caffeine; Central Nervous System Stimulants; Combined Modality Therapy; Doxapram; Drug Therapy, Combination; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Odorants; Physical Stimulation; Respiratory System Agents; Smell

2005
Comparison of the effects of caffeine and doxapram on respiratory and cardiovascular function in foals with induced respiratory acidosis.
    American journal of veterinary research, 2007, Volume: 68, Issue:12

    Topics: Acidosis, Respiratory; Anesthetics, Inhalation; Animals; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Doxapram; Horses; Isoflurane

2007
Doxapram versus placebo in preterm newborns: a study protocol for an international double blinded multicentre randomized controlled trial (DOXA-trial).
    Trials, 2023, Oct-10, Volume: 24, Issue:1

    Topics: Bronchopulmonary Dysplasia; Caffeine; Double-Blind Method; Doxapram; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Multicenter Studies as Topic; Randomized Controlled Trials as Topic

2023

Other Studies

14 other study(ies) available for caffeine and doxapram

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Comparisons between the antianesthetic action of dibutyryl cyclic AMP and analeptic drugs on amobarbital-induced narcosis in the rat.
    Pharmacology, 1976, Volume: 14, Issue:1

    Topics: Amobarbital; Amphetamines; Anesthetics; Animals; Benzamides; Bucladesine; Caffeine; Central Nervous System Stimulants; Doxapram; Male; Pentylenetetrazole; Picrotoxin; Rats; Strychnine; Theophylline

1976
[Ventilatory effects of various respiratory stimulants in awake cats (author's transl)].
    Bulletin europeen de physiopathologie respiratoire, 1979, Volume: 15 Suppl

    Topics: Almitrine; Animals; Caffeine; Carbon Dioxide; Cats; Central Nervous System; Central Nervous System Stimulants; Consciousness; Doxapram; Drug Interactions; Hypercapnia; Oxygen; Peripheral Nerves; Piperazines; Respiration; Respiratory Function Tests; Triazines

1979
Alteration of ovine fetal respiratory-like activity by diazepam, caffeine, and doxapram.
    American journal of obstetrics and gynecology, 1977, Jan-01, Volume: 127, Issue:1

    Topics: Animals; Blood Gas Analysis; Caffeine; Depression, Chemical; Diazepam; Doxapram; Female; Fetal Blood; Fetus; Infusions, Parenteral; Pregnancy; Pressure; Respiration; Sheep; Stimulation, Chemical; Trachea

1977
Interactive ventilatory effects of two respiratory stimulants, caffeine and doxapram, in newborn lambs.
    Biology of the neonate, 1992, Volume: 61, Issue:3

    Topics: Animals; Animals, Newborn; Behavior, Animal; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Doxapram; Drug Synergism; Infusions, Intravenous; Pulmonary Ventilation; Respiration; Sheep; Tidal Volume

1992
Effects of caffeine and doxapram perfusion on local cerebral glucose utilization in conscious rats.
    European journal of pharmacology, 1989, Aug-22, Volume: 167, Issue:2

    Topics: Animals; Autoradiography; Blood Gas Analysis; Blood Pressure; Body Temperature; Brain; Caffeine; Deoxyglucose; Doxapram; Energy Metabolism; Glucose; In Vitro Techniques; Male; Perfusion; Rats; Rats, Inbred Strains

1989
Low-dose doxapram for apnoea of prematurity.
    Lancet (London, England), 1986, Apr-05, Volume: 1, Issue:8484

    Topics: Apnea; Caffeine; Doxapram; Drug Therapy, Combination; Humans; Infant, Newborn; Infant, Premature, Diseases; Pilot Projects; Recurrence

1986
Species dependent effects of doxapram HCl on alcohol dehydrogenase activity.
    European journal of pharmacology, 1969, Volume: 6, Issue:2

    Topics: Alcohol Oxidoreductases; Alcohols; Animals; Bemegride; Benzamides; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Dogs; Doxapram; Electrophoresis; Ethanol; Female; Glycols; Guinea Pigs; Horses; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Methylphenidate; Mice; Microsomes; Morpholines; Nikethamide; Pentylenetetrazole; Propylene Glycols; Pyrrolidinones; Rabbits; Rats; Species Specificity

1969
Possible alterations in brain monoamine metabolism during hypoxia-induced tachypnea in cats.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1980, Volume: 49, Issue:5

    Topics: Aminophylline; Animals; Biogenic Amines; Brain; Caffeine; Carbidopa; Cats; Dihydroxyphenylalanine; Doxapram; Hypercapnia; Hypoxia; Respiration Disorders

1980
Drug-induced changes in fetal breathing activity and sleep state.
    Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:4

    Topics: Animals; Caffeine; Doxapram; Female; Fetus; Indomethacin; Pilocarpine; Pregnancy; Respiration; Sheep; Sleep; Sodium Cyanide

1983
The Pharmacokinetics of Caffeine in Preterm Newborns: No Influence of Doxapram but Important Maturation with Age.
    Neonatology, 2021, Volume: 118, Issue:1

    Topics: Apnea; Caffeine; Doxapram; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases

2021
Not Only Preterm Neonates Mature but Also Traditional Dosing Regimens Have to Mature: The Role of Mathematical Modeling.
    Neonatology, 2021, Volume: 118, Issue:1

    Topics: Caffeine; Clinical Protocols; Doxapram; Gestational Age; Humans; Infant, Newborn; Infant, Premature

2021
chemdatabank.com