caffeine and apnea

caffeine has been researched along with apnea in 303 studies

Research

Studies (303)

Timeframe	Studies, this research(%)	All Research%
pre-1990	73 (24.09)	18.7374
1990's	29 (9.57)	18.2507
2000's	41 (13.53)	29.6817
2010's	104 (34.32)	24.3611
2020's	56 (18.48)	2.80

Authors

Authors	Studies
Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U	1
Aranda, JV; Bergsteinsson, H; Gorman, W; Gunn, T	1
Aranda, JV; Baltassat, P; Bethenod, M; Bory, C; Frederich, A; Porthault, M	2
Boutroy, MJ; Monin, P; Royer, RJ; Royer-Morrot, MJ; Vert, P	2
Aranda, JV; Gunn, TR; Metrakos, K; Riley, P; Willis, D	1
Aranda, JV; Turmen, T	1
Aldridge, A; Aranda, JV; Collinge, JM; Cook, CE; Gorman, W; Loughnan, PM; Neims, AH; Outerbridge, EW	1
Brazier, JL; Renaud, H; Ribon, B; Salle, BL	1
Bada, HS; Khanna, NN; Somani, SM; Tin, AA	1
Aranda, JV; Louridas, TA; Turmen, T	1
Aldridge, A; Aranda, JV; Haber, R; Louridas, AT; Thom, P; Vitullo, BB	1
de Boer, P; de Bruijne, JI; Koppe, JG	1
Riechert, M	1
Lucey, JF	1
Debry, G; Martinet, Y	1
Carnevale, A; Chiarotti, M; De Carolis, MP; De Giovanni, N; Muzii, U; Romagnoli, C; Tortorolo, G; Zecca, E	1
Brown, SS; Chin, KC; Durbin, GM; Hale, KA; Morgan, ME; Scanlon, JE	1
Jongejan, HT; Sauer, PJ; van den Anker, JN	1
Irani, AJ; Merchant, RH	1
Amato, M; Hüppi, P; Isenschmid, M	1
Sacristán del Castillo, JA; Soto Alvarez, J	1
Aujard, Y	1
Gremillet, C; Lequien, P; Lhermitte, M; Morisot, C; Robert, MH; Simoens, C; Trublin, F	1
Erickson, R; Sims, ME; Walther, FJ	1
Baan, J; Ruys, JH; Stijnen, T; Van Bel, F; Van de Bor, M	1
Fink, R; Hannallah, RS; Hicks, JM; Ruttimann, UE; Welborn, LG	1
Fuglsang, G; Jakobsen, P; Kjaer Nielsen, L; Nielsen, K; Sennels, F; Thelle, T	1
Flood, E	1
Noerr, B	1
Braun, RJ; Evans, MA; Kelly, DH; McCulloch, KM; Simms, PE	1
Bairam, A; Vert, P	1
Cattarossi, L; Colacino, V; Janes, A; LoGreco, P; Macagno, F; Rubini, S; Zilli, M	1
Gupta, P; Somani, SM	1
Badoual, J; Blais, JC; Carrier, O; d'Athis, P; Moran, C; Olive, G; Plissonnier, M; Pons, G; Rey, E; Richard, MO	1
Motoya, H; Nakao, T; Umetsu, M; Wakamatsu, A	1
Badoual, J; Carrier, O; d'Athis, P; Moran, C; Olive, G; Pons, G; Rey, E; Richard, MO	1
Congdon, PJ; Faye, S; Hay, AW; Nadkarni, S	1
Boeckx, R; de Soto, H; Fink, R; Hannallah, RS; Ruttimann, UE; Welborn, LG	1
Badoual, J; Carrier, O; Moran, C; Olive, G; Pons, G; Rey, E; Richard, MO	1
Krauss, AN	1
Badonnel, Y; Bairam, A; Boutroy, MJ; Vert, P	1
Broly, F; Carpentier, C; Houdret, N; Lequien, P; Lhermitte, M; Roussel, P; Zaoui, C	1
Sacré, L; Vandenplas, Y	1
Fox, WW; Spitzer, AR	1
Bendell, D; Duke, JC; Mattice, CD; McCaffree, MA; Orr, WC; Toubas, PL	1
Aranda, JV; Davis, JM; Metrakos, K	1
Anwar, M; Graff, M; Hegyi, T; Hiatt, M; Mojica, N; Mondestin, H; Novo, R	1
Kusenbach, G; Reinhardt, D	1
Billon, B; Le Guennec, JC	1
Brouard, C; de Gamarra, E; Flouvat, B; Moriette, G; Murat, I; Pajot, N; Relier, JP; Walti, H	1
Koyama, EA; Spierer, DN	1
Billon, B; Le Guennec, JC; Paré, C	1
Aubertin, D; Cathely, JP; Cormier, JP; Jamain, B; Michon, L; Moreau, M; Touratier, P	1
de Wilde, TW; Koppe, JG; Rietveld, HJ	1
Haley, TJ	1
Labow, R	1
Dandurand, KR	1
Aranda, JV; Beharry, K; Papageorgiou, A; Scalais, E	1
Khanna, NN; Somani, SM	2
Aranda, JV; Davis, J; Grondin, D; Trippenbach, T; Turmen, T; Watters, G; Zinman, R	1
Bielicki, M; Sourgens, H; Staib, AH; von Loewenich, V	1
Aranda, JV; Outerbridge, EW; Trippenbach, T	1
Mullner, JW	1
Maisels, MJ; Marks, KH; Rothberg, AD; Ward, RM	1
Lindström, B; Lönnerholm, G; Paalzow, L; Sedin, G	1
Hargreaves, DB; Lealman, GT; Mulley, BA	1
Horowitz, DA; Jablonski, WJ; Mehta, KA	1
Gorodischer, R; Karplus, M	1
Boyer, A; Chua, C; Khanna, NN; Menke, JA; Miller, J; Somani, SM	1
Alix, D; Berthou, F; Dreano, Y; Gouedard, H; Picart, D; Riche, C	1
Banagale, RC	1
Bada, HS; Khanna, NN; Somani, SM	2
Aranda, JV; Grondin, D; Sasyniuk, BI	1
Aranda, JV; Davis, J; Turmen, T	1
Aranda, JV; Clozel, M; Howell, J	1
Blin, MC; Couchard, M; De Gamarra, E; Dreyfus-Brisac, C; Flouvat, B; Moriette, G; Murat, I; Relier, JP	1
Lipowsky, G; Riechert, M; Stiegler, H; Stöckl, H	1
Floberg, S; Lindström, B; Lönnerholm, G	1
Sawynok, J	1
Brendstrup, L; Greisen, G; Larsen, PB; Lundstrøm, KE; Skov, L	1
Brendstrup, L; Flachs, H; Larsen, PB; Skov, L	1
Greenspun, JC; Welborn, LG	1
Hindmarsh, KW; Kalapurackal, M; Sankaran, K; Tan, L	1
Charles, B; Cowley, D; Gray, P; Sidhu, J; Triggs, E; Tudehope, D	1
Bucher, HU; Duc, G	1
Calhoun, LK	1
Charles, BG; Flenady, VJ; Lee, TC; Steer, PA	1
Charles, B; Flenady, V; Lee, TC; Shearman, A; Steer, P	1
Kotagal, U; Pesce, AJ; Rashkin, M	1
Fang, S; Gamsu, HR; Greenough, A; Marsden, JT; Peters, TJ; Sherwood, RA	1
Burd, RS; Helikson, MA; Tobias, JD	1
Huon, C; Moriette, G; Mussat, P; Parat, S; Rey, E	1
Adhikari, M; Botha, JH; du Preez, MJ; McFadyen, ML	1
Anderson, BJ; Gunn, TR; Holford, NH; Johnson, R	1
Bohnhorst, B; Darraj, S; Poets, CF	1
Tobias, JD	1
DeCristofaro, JD; Katz, S; Subhani, M	1
Henderson-Smart, DJ; Steer, PA	2
Henderson-Smart, DJ; Steer, P	4
Ahn, HW; Choi, JH; Park, KJ; Shin, WG; Suh, OK	1
Erenberg, A; Haack, DG; Hicks, GM; Leff, RD; Mosdell, KW; Wynne, BA	1
Bertini, G; Dani, C; Martelli, E; Reali, MF; Rubaltelli, FF; Tronchin, M; Wiechmann, L	1
Bhatia, J	1
Comer, AM; Figgitt, DP; Perry, CM	1
Bauer, J; Hentschel, R; Linderkamp, O; Maier, K	1
Aggarwal, R; Deorari, AK; Paul, VK; Singhal, A	1
Choi, DM; Davis, L	1
Gannon, BA	1
Chirino-Barcelo, Y; Khoo, YM; Lee, HS; Ong, D; Tan, KL	1
Bhatt-Mehta, V; Schumacher, RE	1
Belkahia, C; Boukef-Larguèche, S; Chaouachi, S; Cherif, A; Klouz, A; Marrakchi, Z	1
Belkahia, C; Boukef-Larguèche, S; Cherif, A; Klouz, A; Zouari, B	1
GESHELIN, SA	2
Anderson, BJ; McNamara, DG; Nixon, GM	1
Gaugler, C; Marlier, L; Messer, J	1
Padmakumar, B; Sajit, NT; Steggall, M	1
Beedgen, B; Hoecker, C; Linderkamp, O; Nelle, M; Rengelshausen, J	1
Bairam, A; Kinkead, R; Montandon, G	1
Barrington, KJ; Davis, P; Doyle, LW; Ohlsson, A; Roberts, RS; Schmidt, B; Solimano, A; Tin, W	2
Bancalari, E	2
Cattarossi, L; Logreco, P; Macagno, F; Savoia, M; Violino, M	1
Baudon, JJ; Biran-Mucignat, V; Ducrocq, S; Gold, F; Lebas, F	1
Baudon, JJ; Biran-Mucignat, V; Boelle, PY; Ducrocq, S; Gold, F; Lebas, F	1
Coulter, DM	1
Hand, IL; Noble, LM	1
Duke, T; McCallum, AD	1
Hutchison, AA; Leon, AE; Ma, CX; Michienzi, K	1
Aranda, JV; Botica, ML; Natarajan, G; Thomas, R	1
Stevenson, DK	1
Bairam, A; Joseph, V; Kinkead, R; Lajeunesse, Y; Montandon, G	1
Bin-Nun, A; Ionchev, A; Meadow, W; Soloveychik, V; Sriram, S	1
Charles, BG; Flenady, VJ; Gray, PH; Shearman, A; Steer, PA; Townsend, SR	1
Bohlin, K; Jonsson, B; Kamper, J; Lindwall, R; Verder, H	1
Bacopoulou, F; Markantonis, SL; Skouroliakou, M	1
Asztalos, E; Davis, PG; Doyle, LW; Haslam, R; Roberts, RS; Schmidt, B; Sinha, S; Tin, W	1
El Ayoubi, M; Lescure, S; Lopez, E; Moriette, G	1
Poets, CF	2
Bairam, A; Joseph, V; Julien, CA	2
Powell, E; Winckworth, LC	1
Aranda, JV; Beharry, K; Davis, J; Natarajan, G; Valencia, GB	1
Mathew, OP	1
Rockley, TJ	1
De Paoli, AG; Henderson-Smart, DJ	2
Doyle, LW; Dukhovny, D; Kamholz, KL; Kok, JH; Lorch, SA; Mao, W; Roberts, RS; Schmidt, B; Wang, N; Zupancic, JA	1
Davis, P; Doyle, LW; Roberts, RS; Schmidt, B	1
Anderson, PJ; Asztalos, EV; Barrington, KJ; Davis, PG; Dewey, D; Doyle, LW; Grunau, RE; Moddemann, D; Ohlsson, A; Roberts, RS; Schmidt, B; Solimano, A; Tin, W	1
Maitre, NL; Stark, AR	1
Vavasseur, C	1
Cesar, K; Iolster, T; Latifi, S; White, D	1
Della Pasqua, O; Field, DJ; Gade, S; Kairamkonda, V; Mulla, H; Pandya, HC; Patel, P; Spooner, N	1
Bedetta, M; Paolillo, P; Picone, S	1
Bairam, A; Boudaa, N; Carrière, V; Germim, PS; Pasquier, JC; Praud, JP; Samson, N	1
Arnal, AV; Bartlett, D; Gore, JL; Leiter, JC; Rudkin, A	1
Chawla, R; Haloi, P; Kumar, M; Singh, M	1
Abu Jawdeh, EG; Argus, BM; Bandyopadhyay, A; Davis, PG; Limrungsikul, A; Martin, RJ; Nakad, PE; O'Riordan, M; Supapannachart, S; Yunis, KA	1
Arand, J; Engel, C; Poets, CF; Vatlach, S	1
Schoen, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Yu, T	1
Blazer, S; Haleluya, NS; Ulanovsky, I; Weissman, A	1
Anderson, PJ; Davis, PG; Doyle, LW; Grunau, RE; Herlenius, E; Moddemann, D; O'Brien, K; Roberts, R; Sankaran, K; Schmidt, B	1
Bassler, D; Kreutzer, K	1
Aschner, JL; Chan, J; Key, AP; Lambert, WE; Maitre, NL; Stark, AR	1
Butler, TJ; Firestone, KS; Grow, JL; Kantak, AD	1
Asztalos, E; Bhattacharjee, R; Biggs, SN; Bradford, R; Cheshire, M; Costantini, L; D'ilario, J; Davey, M; Dix, J; Doyle, LW; Gibbons, J; Horne, RS; Marcus, CL; Meltzer, LJ; Narang, I; Nixon, GM; Opie, G; Roberts, RS; Schmidt, B; Traylor, J	1
Khan, SR; Poets, CF	1
Diab, M; Gad, GI; Hassanein, SM; Ismail, RI	1
Barrington, K; Lee, SK; Lodha, A; McMillan, DD; Seshia, M; Shah, PS; Yang, J	1
Chen, DM; Wang, RQ; Xu, JL	1
Andersen, ML; Araujo, P; Tufik, S	1
Marcus, CL	1
Clark, MT; Delos, JB; Fairchild, KD; Kattwinkel, J; Lake, DE; Lee, H; Mennen, AC; Mohr, MA; Moorman, JR; Sinkin, RA; Vergales, BD	1
Ding, X; Greer, JJ; Ren, J	1
Abdel-Hady, H; Mohammed, S; Nasef, N; Nour, I; Shabaan, AE; Shouman, B	1
Nagesh, NK; Razak, A	1
Beck, J; Lehtonen, L; Leppäsalo, J; Parikka, V; Soukka, H; Zhai, Q	1
Bairam, A; Joseph, V; Mubayed, S; Uppari, N	1
Davidson, D; DeCristofaro, J; Demeglio, D; Doyle, J; Katz, S; Varela, M	1
Di Fiore, JM; Gauda, E; MacFarlane, P; Martin, RJ; Poets, CF	1
Chung, S; Chung, SH; Kim, KS; Kim, SN; Lim, G; Park, HW	1
Liu, G; Tian, X; Zhao, Y	1
Carnielli, VP; Fabbri, L; Ferrari, F; Kiechl-Kohlendorfer, U; Lasagna, G; Lista, G; Papagaroufalis, K; Polackova, R; Saenz, P	1
Carlos, C; Consenstein, L; Cóté, A; Franco, P; Hageman, J; Kelly, D; McEntire, B; Pellerite, M; Raoux, A; Rusciolelli, C	1
Franco, R; Martínez-Pinilla, E; Oñatibia-Astibia, A	1
Delos, J; Fairchild, K; Kattwinkel, J; Lake, D; Mohr, M; Moorman, JR; Paget-Brown, A; Tabacaru, C	1
Huang, JH; Wen, XH; Wu, WY; Yu, M; Zhang, XZ; Zhu, R	1
Armanian, AM; Faghihian, E; Iranpour, R; Salehimehr, N	1
Ahlawat, R; Chavez-Valdez, R; Gauda, EB; Wills-Karp, M	1
Ahmed, W; Alansari, K; Davidson, BL; El Tatawy, LA; Khalafalla, H; Toaimah, FH	1
Balch, AH; Korgenski, EK; Sherwin, CM; Ward, RM; Yu, T	1
Barco, S; Bruschettini, M; Cangemi, G; Chinea, B; Gennai, I; Ramenghi, LA; Risso, F; Romantsik, O; Tripodi, G	1
Chen, C; Mu, DZ; Shi, J; Shu, XX; Tang, J; Yang, XY	1
Ahlers-Schmidt, CR; Bloom, BT; Engel, M; Powell, MB	1
Onland, W; Ten Hove, CH; van Kaam, AH; Vliegenthart, RJ	1
Dobson, NR; Patel, RM	1
Laviolle, B; Maheux, A; Pladys, P	1
Atik, A; Cheong, J; De Matteo, R; Doyle, LW; Harding, R; Kondos-Devcic, D; Tolcos, M	1
Duan, YH; Han, JT; Su, P; Wei, QZ; Zhang, X	1
Chauhan, M; Gray, PH	1
Amberson, M; Dukhovny, D; Freiberger, C; Montenegro, BL; Rhein, LM; Veit, L	1
Ahmad, A; Klein, B; Mondal, T	1
Nanu, R; Ray, RS; Sun, JJ	1
Bairam, A; Joseph, V; Uppari, NP	1
Anderson, PJ; Asztalos, EV; Costantini, L; D'Ilario, J; Davis, PG; Dewey, D; Doyle, LW; Grunau, RE; Moddemann, D; Nelson, H; Ohlsson, A; Roberts, RS; Schmidt, B; Solimano, A; Tin, W	1
Bhat Y, R; Jayashree, P; Kamath, A; Lewis, LES; Najih, M; Shashikala, -; Shivakumar, M	1
Cheong, JLY; Doyle, LW; Ranganathan, S	1
Abu-Shaweesh, JM; Martin, RJ	1
Datta, AN; Jost, K; Koch, G; Pfister, M; Schulzke, SM; van den Anker, J	1
McDonald, FB; O'Halloran, KD	1
Jayashree, P; Khurana, S; Lewis, LES; Ramesh Bhat, Y; Shivakumar, M; Sujith Kumar Reddy, GV	1
Chalwadi, UK; Kalappanavar, NK	1
Shivakumar, M; Simon Lewis, LE	1
Carlo, WA; Gentle, SJ; Travers, CP	1
Kamimura, H; Nagasato, A; Nakamura, M	1
Hutten, GJ; Miedema, M; Onland, W; van Kaam, AH; Vliegenthart, R	1
Baerts, W; Dix, LML; Lemmers, PMA; van Bel, F	1
Anderson, PJ; Asztalos, EV; Costantini, L; D'Ilario, J; Davis, PG; Dewey, D; Doyle, LW; Grunau, RE; Moddemann, D; Mürner-Lavanchy, IM; Nelson, H; Ohlsson, A; Roberts, RS; Schmidt, B; Solimano, A; Tin, W	1
Dobson, NR; Hunt, CE	1
Dempsey, EM; McDonald, FB; O'Halloran, KD	1
Kamath, A; Lewis, LES; M, S; Nayak, K; Purkayastha, J	1
Andersson, S; Kirjavainen, T; Mikkola, K; Rantakari, K; Seppä-Moilanen, M	1
Brattström, P; Bruschettini, M; Ley, D; Russo, C	2
Hinder, M; Huvanandana, J; McEwan, A; Thamrin, C; Tracy, MB	1
Álvarado Socarras, JL	1
Dong, LB; Li, YF; Qiao, S; Zhang, Y	1
Chen, X; Cheng, R; Feng, Y; Mao, XN; Qiu, J; Zhao, L	1
Hutten, GJ; Miedema, M; Onland, W; van Kaam, AH; Vliegenthart, RJS	1
Chen, J; Chen, X; Jin, L	1
Jain, VG; Jobe, A; Patel, RM; Saroha, V	1
Anderson, PJ; Asztalos, EV; Doyle, LW; Grunau, RE; Moddemann, D; Roberts, RS; Schmidt, B	1
Gao, Z; Han, D; Kou, C; Li, Z; Liu, Z; Wu, W; Zhang, Y	1
Bendel-Stenzel, E; Chhabra, R; Harper, B; Ku, L; Laughon, M; Moya, F; Payne, EH; Puia-Dumitrescu, M; Smith, PB; Soriano, A; Wade, KC; Zhao, J	1
Lyu, Y; Wang, LF; Yang, ZY; Zhang, HT; Zhang, X	1
Ihara, K; Maeda, T; Sekiguchi, K; Wasada, R	1
MacFarlane, PM; Mitchell, L	1
McPherson, C; Rostas, SE	1
Bruschettini, M; Johansson, M; Juhl Jørgensen, K	1
Clark, RH; Greenberg, RG; Ji, D; Ku, L; Laughon, M; Smith, PB; Zimmerman, KO	1
Brossier, D; Denis, M; Faucon, C; Goyer, I; Heuzé, N; Jokic, M; Porcheret, F	1
Bruschettini, M; Johansson, M; Nava, C; Nylander Vujovic, S	1
Aghai, ZH; Amendolia, B; Bhat, V; Chung, J; Nakhla, T; Saslow, J; Slater-Myer, L; Tran Lopez, K	1
Abushanab, D; Al-Badriyeh, D; Al-Shaibi, S; Alhersh, E	1
Chen, P; Huang, L; Wan, L	1
Ding, Y; Gan, JM; He, T; Li, W; Liao, ZC; Wang, MJ; Yue, SJ	1
Liu, S; Liu, Y; Wang, X; Xu, F; Yang, L; Yuan, X; Zhang, R; Zhang, X; Zhu, C	1
Gao, XB; Jacqz-Aigrain, E; Jiang, ZH; Ni, SQ; Wang, CH; Wu, YE; Yang, F; Zhao, W; Zheng, Y	1
Di, X; Fan, J; Guo, A; Hu, X; Huang, L; Xie, H; Xue, J; Zhao, P; Zhu, Z	1
Alsweiler, JM; McKinlay, CJD; McNamara, DG; Oliphant, EA	1
Grunau, RE; Synnes, A	1
Cheong, JLY; Doyle, LW	1
Davis, PG	1
Patel, RM; Saroha, V	1
Chen, F; Cheng, R; Guo, HL; He, X; Jia, WW; Li, L; Liu, Y; Lu, KY; Ni, MM; Qiu, JC; Xu, J	1
Eichenwald, EC	1
Ayede, AI; Ekhaguere, OA; Ezeaka, CV	1
Aranda, JV; Beharry, KD	1
Jain, N; Nair, PMC; Nandakumar, A; Pournami, F; Prabhakar, J; Prakash, R	1
Engbers, AGJ; Flint, RB; Knibbe, CAJ; Koch, BCP; Poets, CF; Reiss, IKM; Simons, SHP; Völler, S	1
Conlon, S; Di Fiore, JM; Martin, RJ	1
Elmowafi, M; Mohsen, N; Nasef, N; Nour, I	1
Ibrahim, NR; Mohd Kori, AM; Nasir, A; Van Rostenberghe, H; Yaacob, NM	1
Gao, X; Jiang, Z; Liang, J; Ni, S	1
Gueta, I; Hanna, M; Loebstein, R; Rosen, C; Strauss, T; Taran, C; Yarden-Bilavsky, H	1
Kumar, P; Saini, SS	1
Andersson, S; Kirjavainen, T; Seppä-Moilanen, M	1
Andersen, L; Ariagno, S; Collura, C; Thorvilson, M	1
Dong, W; Lei, X; Yang, Y; Yuan, Y	1
Armanian, AM; Feizi, A; Iranpour, R; Miladi, N	1
Bancalari, E; Chavez, L	1
Cai, X; Chen, J; Gyabaah, AT; Huang, ZL; Li, Y; Li, Z; Ma, C; Shi, H; Tu, Y; Yu, C	1
Boyle, MA; Egan, R; McElligott, F; Smith, A	1
Chen, F; Cheng, R; Dai, HR; Ding, XS; Du, FF; Guo, HL; Hu, YH; Long, JY; Tian, M; Xia, Y; Xu, J	1
Lin, XZ; Xie, JB	1
Hadi, MA; Kassab, YW; Khairuddin, N; Ming, LC; Yao, LM; Yun, WZ	1
Chen, F; Cheng, R; Dai, HR; Ding, XS; Guo, HL; He, X; Hu, YH; Jiao, Z; Liu, Y; Lu, KY; Xu, J	1
Jiang, H; Li, Y; Liu, W; Miao, Y; Wang, A; Zhang, Y; Zhao, S; Zhou, Y	1
Andrés, JLP; Cañada-Martínez, AJ; García-Robles, A; González, PS; Pericás, CC; Ponce-Rodriguez, HD; Solaz-García, Á; Vento, M; Verdú-Andrés, J	1
Bona, MD; Boni, L; Cecchi, A; Ciarcià, M; Dani, C; la Marca, G; Luzzati, M; Miselli, F; Remaschi, G	1
Ali, A; Ambreen, G; Aslam, MS; Hussain, K; Kumar, M; Salat, MS; Saleem, SM; Shah, SAA; Tahir, A	1
Prakash, R	1
Kannan Loganathan, P; Nair, V	1
Brattström, P; Bruschettini, M; Davis, PG; Onland, W; Russo, C; Soll, R	1
Ciarcià, M; Corsini, I; Dani, C; Fusco, M; Gitto, E; Leonardi, V; Manti, S; Marseglia, L	1
Schmidt, B	1
Jiang, H; Li, Y; Liu, W; Miao, Y; Teng, P; Wang, A; Zhang, Y; Zhao, S	1
Itoh, S; Kawaguchi, N; Konishi, Y; Koyano, K; Kuboi, T; Kusaka, T; Nakamura, S; Nakano, A; Nishioka, K; Noguchi, Y; Okada, H; Sadamura, T; Sugino, M; Tadatomo, Y	1
Akdere, SK; Atalah, YEY; Barış, HE; Boran, P; Eralp, EE; Gücüyener, K; Özdemir, H; Özek, E; Sabancı, M	1
Bruschettini, M; Marques, KA; Moresco, L; Sjögren, A; Soll, R	1
Avdic, E; Bruschettini, M; Evans, S; Fiander, M; Pessano, S; Soll, R	1
Bruschettini, M; Davis, PG; Fiander, M; Marques, KA; Roehr, CC; Soll, R	1

Reviews

62 review(s) available for caffeine and apnea

Article	Year
Methylxanthines in apnea of prematurity. Clinics in perinatology, 1979, Volume: 6, Issue:1 Topics: Apnea; Caffeine; Hemodynamics; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Respiration; Theophylline	1979
Pharmacotherapy of neonatal apnea. Indian pediatrics, 1991, Volume: 28, Issue:11 Topics: Apnea; Caffeine; Citrates; Doxapram; Drug Combinations; Humans; Infant, Newborn; Theophylline	1991
Caffeine: a new look at an age-old drug. International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:11 Topics: Apnea; Arteriosclerosis; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Neoplasms	1988
Metabolism and pharmacokinetics of theophylline in human neonates, children, and adults. Drug metabolism reviews, 1983, Volume: 14, Issue:2 Topics: Adult; Age Factors; Apnea; Asthma; Biotransformation; Bradycardia; Caffeine; Child; Female; Half-Life; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Kinetics; Male; Methylation; Pulmonary Edema; Theophylline; Tissue Distribution	1983
Pharmacological rationale for the clinical use of caffeine. Drugs, 1995, Volume: 49, Issue:1 Topics: Animals; Apnea; Caffeine; Central Nervous System; Headache; Humans; Hypotension; Obesity; Pain; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists	1995
Anesthesia and apnea. Perioperative considerations in the former preterm infant. Pediatric clinics of North America, 1994, Volume: 41, Issue:1 Topics: Age Factors; Anemia; Anesthesia; Apnea; Bradycardia; Caffeine; Clinical Protocols; Gestational Age; Humans; Incidence; Infant, Newborn; Infant, Premature; Respiratory Mechanics; Risk Factors	1994
Pharmacologic management of apnea of prematurity. The Journal of perinatal & neonatal nursing, 1996, Volume: 9, Issue:4 Topics: Apnea; Bronchodilator Agents; Caffeine; Drug Monitoring; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1996
Standards of laboratory practice: theophylline and caffeine monitoring. National Academy of Clinical Biochemistry. Clinical chemistry, 1998, Volume: 44, Issue:5 Topics: Apnea; Bronchodilator Agents; Caffeine; Drug Monitoring; Humans; Infant, Newborn; Lung Diseases, Obstructive; Quality Control; Specimen Handling; Theophylline	1998
Caffeine versus theophylline for apnea in preterm infants. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Apnea; Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline	2000
Postoperative caffeine for preventing apnea in preterm infants. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Anesthesia, General; Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Postoperative Complications; Postoperative Period	2000
Methylxanthine treatment for apnea in preterm infants. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline; Vasodilator Agents; Xanthines	2000
Current options in the management of apnea of prematurity. Clinical pediatrics, 2000, Volume: 39, Issue:6 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Doxapram; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline; Xanthines	2000
Caffeine citrate: a review of its use in apnoea of prematurity. Paediatric drugs, 2001, Volume: 3, Issue:1 Topics: Apnea; Brain; Caffeine; Central Nervous System Stimulants; Citrates; Drug Combinations; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic; Respiration	2001
Methylxanthine treatment for apnea in preterm infants. The Cochrane database of systematic reviews, 2001, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline; Vasodilator Agents; Xanthines	2001
Prophylactic caffeine to prevent postoperative apnea following general anesthesia in preterm infants. The Cochrane database of systematic reviews, 2001, Issue:4 Topics: Anesthesia, General; Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Postoperative Complications; Postoperative Period	2001
Apnea in the newborn. Indian journal of pediatrics, 2001, Volume: 68, Issue:10 Topics: Aminophylline; Apnea; Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Positive-Pressure Respiration; Respiration, Artificial	2001
Theophylline or caffeine: which is best for apnea of prematurity? Neonatal network : NN, 2000, Volume: 19, Issue:8 Topics: Apnea; Caffeine; Citrates; Drug Combinations; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Theophylline; Treatment Outcome	2000
Treatment of apnea of prematurity. Paediatric drugs, 2003, Volume: 5, Issue:3 Topics: Aminophylline; Apnea; Caffeine; Clinical Trials as Topic; Doxapram; Humans; Infant, Newborn; Infant, Premature; Respiratory System Agents; Theophylline	2003
Methylxanthines for the treatment of apnea associated with bronchiolitis and anesthesia. Paediatric anaesthesia, 2004, Volume: 14, Issue:7 Topics: Anesthesia, General; Apnea; Bronchiolitis; Caffeine; Clinical Trials as Topic; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Respiratory System Agents; Theophylline	2004
Evidence behind the WHO guidelines: hospital care for children: is caffeine useful in the prevention of apnoea of prematurity? Journal of tropical pediatrics, 2007, Volume: 53, Issue:2 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Hospitals; Humans; Infant, Newborn; Infant, Premature; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; World Health Organization	2007
Nasal CPAP and surfactant for treatment of respiratory distress syndrome and prevention of bronchopulmonary dysplasia. Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:9 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Citrates; Combined Modality Therapy; Continuous Positive Airway Pressure; Humans; Infant, Newborn; Positive-Pressure Respiration; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn	2009
[Apnea of prematurity: what's new?]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17, Issue:2 Topics: Apnea; Bradycardia; Brain Damage, Chronic; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Citrates; Combined Modality Therapy; Continuous Positive Airway Pressure; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases; Neonatal Screening; Oxygen; Risk Factors	2010
Interventions for apnoea of prematurity: a personal view. Acta paediatrica (Oslo, Norway : 1992), 2010, Volume: 99, Issue:2 Topics: Amino Acids; Apnea; Caffeine; Continuous Positive Airway Pressure; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Oxygen Inhalation Therapy; Posture	2010
Caffeine versus theophylline for apnea in preterm infants. The Cochrane database of systematic reviews, 2010, Jan-20, Issue:1 Topics: Apnea; Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Theophylline	2010
Question 1 Does caffeine treatment for apnoea of prematurity improve neurodevelopmental outcome in later life? Archives of disease in childhood, 2010, Volume: 95, Issue:9 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Cognition Disorders; Developmental Disabilities; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2010
Caffeine impact on neonatal morbidities. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2010, Volume: 23 Suppl 3 Topics: Animals; Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Morbidity; Respiration, Artificial	2010
Apnea of prematurity: pathogenesis and management strategies. Journal of perinatology : official journal of the California Perinatal Association, 2011, Volume: 31, Issue:5 Topics: Apnea; Arrhythmias, Cardiac; Brain Stem; Caffeine; Central Nervous System Stimulants; Continuous Positive Airway Pressure; Fetal Organ Maturity; Humans; Hypercapnia; Hypoxia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Prognosis; Receptors, Purinergic P1; Respiratory Rate; Respiratory System	2011
Methylxanthine treatment for apnoea in preterm infants. The Cochrane database of systematic reviews, 2010, Dec-08, Issue:12 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intermittent Positive-Pressure Ventilation; Randomized Controlled Trials as Topic; Theophylline; Vasodilator Agents; Xanthines	2010
Prophylactic methylxanthine for prevention of apnoea in preterm infants. The Cochrane database of systematic reviews, 2010, Dec-08, Issue:12 Topics: Apnea; Bradycardia; Caffeine; Central Nervous System Stimulants; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Recurrence; Theophylline; Xanthines	2010
Caffeine citrate: when and for how long. A literature review. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25 Suppl 3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Humans; Infant, Newborn; Infant, Premature, Diseases	2012
Use of methylxanthine therapies for the treatment and prevention of apnea of prematurity. Paediatric drugs, 2014, Volume: 16, Issue:2 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Drug Monitoring; Humans; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Theophylline	2014
Caffeine for apnea of prematurity: a neonatal success story. Neonatology, 2014, Volume: 105, Issue:4 Topics: Animals; Apnea; Birth Weight; Caffeine; Cost-Benefit Analysis; Drug Costs; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Lung; Respiratory System Agents; Treatment Outcome	2014
An Overview on the Respiratory Stimulant Effects of Caffeine and Progesterone on Response to Hypoxia and Apnea Frequency in Developing Rats. Advances in experimental medicine and biology, 2015, Volume: 860 Topics: Age Factors; Animals; Animals, Newborn; Apnea; Caffeine; Heart Rate; Hypoxia; Progesterone; Rats; Respiration	2015
Cardiorespiratory events in preterm infants: interventions and consequences. Journal of perinatology : official journal of the California Perinatal Association, 2016, Volume: 36, Issue:4 Topics: Animals; Apnea; Bradycardia; Caffeine; Central Nervous System Stimulants; Continuous Positive Airway Pressure; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lung; Oxygen; Respiration, Artificial; Retinopathy of Prematurity	2016
Early Caffeine Use in Very Low Birth Weight Infants and Neonatal Outcomes: A Systematic Review and Meta-Analysis. Journal of Korean medical science, 2015, Volume: 30, Issue:12 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Citrates; Enterocolitis, Necrotizing; Humans; Infant; Infant Mortality; Infant, Newborn; Infant, Very Low Birth Weight; Risk Factors; Treatment Outcome	2015
The potential of methylxanthine-based therapies in pediatric respiratory tract diseases. Respiratory medicine, 2016, Volume: 112 Topics: Adolescent; Apnea; Asthma; Bronchodilator Agents; Caffeine; Child; Child, Preschool; Cough; Humans; Infant; Infant, Newborn; Infant, Premature; Phosphodiesterase Inhibitors; Theobromine; Theophylline; Xanthines	2016
Doxapram Treatment for Apnea of Prematurity: A Systematic Review. Neonatology, 2017, Volume: 111, Issue:2 Topics: Apnea; Caffeine; Doxapram; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Respiratory System Agents; Theophylline	2017
The Role of Caffeine in Noninvasive Respiratory Support. Clinics in perinatology, 2016, Volume: 43, Issue:4 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Noninvasive Ventilation; Respiratory Distress Syndrome, Newborn	2016
Caffeine for apnea of prematurity: Effects on the developing brain. Neurotoxicology, 2017, Volume: 58 Topics: Animals; Apnea; Brain; Caffeine; Central Nervous System Stimulants; Humans	2017
Caffeine use in the neonatal intensive care unit. Seminars in fetal & neonatal medicine, 2017, Volume: 22, Issue:5 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Intensive Care Units, Neonatal	2017
Caffeine controversies. Current opinion in pediatrics, 2018, Volume: 30, Issue:2 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Drug Administration Schedule; Ductus Arteriosus, Patent; Humans; Infant, Newborn; Infant, Premature	2018
High versus standard dose caffeine for apnoea: a systematic review. Archives of disease in childhood. Fetal and neonatal edition, 2018, Volume: 103, Issue:6 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Humans; Infant; Infant Mortality; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Treatment Outcome	2018
Caffeine: an evidence-based success story in VLBW pharmacotherapy. Pediatric research, 2018, Volume: 84, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Evidence-Based Medicine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Inflammation; Motor Disorders; Patient Safety; Retinopathy of Prematurity; Vision Disorders; Xanthines	2018
High-versus low-dose caffeine in preterm infants: a systematic review and meta-analysis. Acta paediatrica (Oslo, Norway : 1992), 2019, Volume: 108, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant; Infant Mortality; Infant, Newborn; Infant, Premature	2019
Efficacy and Safety of Different Maintenance Doses of Caffeine Citrate for Treatment of Apnea in Premature Infants: A Systematic Review and Meta-Analysis. BioMed research international, 2018, Volume: 2018 Topics: Apnea; Caffeine; Citrates; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Randomized Controlled Trials as Topic	2018
Is early caffeine therapy safe and effective for ventilated preterm infants? Journal of perinatology : official journal of the California Perinatal Association, 2019, Volume: 39, Issue:5 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic	2019
Mechanistic actions of oxygen and methylxanthines on respiratory neural control and for the treatment of neonatal apnea. Respiratory physiology & neurobiology, 2020, Volume: 273 Topics: Animals; Apnea; Caffeine; Continuous Positive Airway Pressure; Humans; Infant, Newborn; Infant, Newborn, Diseases; Oxygen; Respiratory Physiological Phenomena; Xanthines	2020
Caffeine Therapy in Preterm Infants: The Dose (and Timing) Make the Medicine. Neonatal network : NN, 2019, Nov-01, Volume: 38, Issue:6 Topics: Airway Extubation; Apnea; Caffeine; Central Nervous System; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care, Neonatal; Respiratory System; Treatment Outcome	2019
Confounding biases in studies on early- versus late-caffeine in preterm infants: a systematic review. Pediatric research, 2020, Volume: 88, Issue:3 Topics: Apnea; Caffeine; Drug Administration Schedule; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Respiration; Risk Assessment	2020
Caffeine for the Treatment of Apnea in the Neonatal Intensive Care Unit: A Systematic Overview of Meta-Analyses. Paediatric drugs, 2020, Volume: 22, Issue:4 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Randomized Controlled Trials as Topic; Theophylline; Treatment Outcome	2020
Neurodevelopmental outcomes after neonatal caffeine therapy. Seminars in fetal & neonatal medicine, 2020, Volume: 25, Issue:6 Topics: Animals; Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Citrates; Developmental Disabilities; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Neurodevelopmental Disorders	2020
Caffeine for preterm infants: Fixed standard dose, adjustments for age or high dose? Seminars in fetal & neonatal medicine, 2020, Volume: 25, Issue:6 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Cerebral Hemorrhage; Citrates; Dose-Response Relationship, Drug; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infant, Premature, Diseases	2020
National and international guidelines for neonatal caffeine use: Are they evidenced-based? Seminars in fetal & neonatal medicine, 2020, Volume: 25, Issue:6 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Evidence-Based Medicine; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Observational Studies as Topic	2020
Caffeine and bronchopulmonary dysplasia: Clinical benefits and the mechanisms involved. Pediatric pulmonology, 2022, Volume: 57, Issue:6 Topics: Animals; Apnea; Bronchopulmonary Dysplasia; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2022
Caffeine: Some of the Evidence behind Its Use and Abuse in the Preterm Infant. Neonatology, 2022, Volume: 119, Issue:4 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2022
[Recent research on gene polymorphisms related to caffeine therapy in preterm infants with apnea of prematurity]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2022, Jul-15, Volume: 24, Issue:7 Topics: Apnea; Caffeine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infant, Premature, Diseases; Polymorphism, Single Nucleotide	2022
Comparative efficacy and safety of caffeine citrate and aminophylline in treating apnea of prematurity: A systematic review and meta-analysis. PloS one, 2022, Volume: 17, Issue:9 Topics: Aminophylline; Apnea; Caffeine; Citrates; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infant, Premature, Diseases	2022
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity. The Cochrane database of systematic reviews, 2023, 04-11, Volume: 4 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Child; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature, Diseases	2023
Effect of prophylactic caffeine in the treatment of apnea in very low birth weight infants: a meta-analysis. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2023, Volume: 36, Issue:1 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Respiration, Artificial	2023
Caffeine versus other methylxanthines for the prevention and treatment of apnea in preterm infants. The Cochrane database of systematic reviews, 2023, 10-04, Volume: 10 Topics: Aminophylline; Apnea; Birth Weight; Bronchopulmonary Dysplasia; Caffeine; Hearing Loss; Humans; Infant, Extremely Premature; Infant, Newborn; Randomized Controlled Trials as Topic; Theophylline	2023
Doxapram for the prevention and treatment of apnea in preterm infants. The Cochrane database of systematic reviews, 2023, 10-25, Volume: 10 Topics: Aminophylline; Apnea; Caffeine; Doxapram; Humans; Infant, Newborn; Infant, Premature; Lung Diseases	2023
Methylxanthine for the prevention and treatment of apnea in preterm infants. The Cochrane database of systematic reviews, 2023, 10-31, Volume: 10 Topics: Apnea; Caffeine; Cerebral Palsy; Disabled Persons; Humans; Infant; Infant, Newborn; Infant, Premature; Lung Diseases; Motor Disorders; Oxygen	2023

Trials

53 trial(s) available for caffeine and apnea

Article	Year
Caffeine or theophylline for neonatal apnoea? Archives of disease in childhood, 1992, Volume: 67, Issue:4 Spec No Topics: Apnea; Caffeine; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Infant, Premature; Theophylline; Time Factors; Treatment Outcome	1992
High-dose caffeine suppresses postoperative apnea in former preterm infants. Anesthesiology, 1989, Volume: 71, Issue:3 Topics: Anesthesia, General; Apnea; Bradycardia; Caffeine; Clinical Trials as Topic; Double-Blind Method; Hernia, Inguinal; Humans; Infant; Infant, Newborn; Infant, Premature; Monitoring, Physiologic; Postoperative Complications; Prospective Studies; Random Allocation	1989
The effect of caffeine compared with theophylline in the treatment of idiopathic apnea in premature infants. Acta paediatrica Scandinavica, 1989, Volume: 78, Issue:5 Topics: Administration, Oral; Apnea; Bradycardia; Caffeine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant, Newborn; Infant, Premature; Male; Random Allocation; Theophylline	1989
The use of caffeine in the control of post-anesthetic apnea in former premature infants. Anesthesiology, 1988, Volume: 68, Issue:5 Topics: Anesthesia, Inhalation; Apnea; Caffeine; Clinical Trials as Topic; Double-Blind Method; Hernia, Inguinal; Humans; Infant, Newborn; Infant, Premature; Postoperative Complications; Prospective Studies; Random Allocation	1988
Theophylline versus caffeine: comparative effects in treatment of idiopathic apnea in the preterm infant. The Journal of pediatrics, 1987, Volume: 110, Issue:4 Topics: Apnea; Caffeine; Double-Blind Method; Heart Rate; Humans; Infant, Newborn; Infant, Premature, Diseases; Natriuresis; Random Allocation; Respiration; Theophylline	1987
Comparative efficacy of theophylline and caffeine in the treatment of idiopathic apnea in premature infants. American journal of diseases of children (1960), 1985, Volume: 139, Issue:7 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Tachycardia; Theophylline	1985
Effects of caffeine being studied for treatment of apnea in newborns. Canadian Medical Association journal, 1983, Aug-01, Volume: 129, Issue:3 Topics: Apnea; Caffeine; Clinical Trials as Topic; Double-Blind Method; Humans; Infant, Newborn; Infant, Newborn, Diseases	1983
The efficacy of caffeine in the treatment of recurrent idiopathic apnea in premature infants. The Journal of pediatrics, 1981, Volume: 99, Issue:6 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Prospective Studies; Recurrence	1981
Cerebral blood flow and left ventricular output in spontaneously breathing, newborn preterm infants treated with caffeine or aminophylline. Acta paediatrica (Oslo, Norway : 1992), 1995, Volume: 84, Issue:1 Topics: Aminophylline; Analysis of Variance; Apnea; Caffeine; Cerebrovascular Circulation; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Regression Analysis; Respiration; Stroke Volume; Ventricular Function, Left	1995
Aminophylline versus caffeine citrate for apnea and bradycardia prophylaxis in premature neonates. Acta paediatrica (Oslo, Norway : 1992), 1995, Volume: 84, Issue:4 Topics: Apnea; Bradycardia; Caffeine; Citrates; Drug Combinations; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1995
Saliva as a valid alternative to serum in monitoring intravenous caffeine treatment for apnea of prematurity. Therapeutic drug monitoring, 1996, Volume: 18, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Monitoring; Enzyme Multiplied Immunoassay Technique; Female; Humans; Infant, Newborn; Infant, Premature; Injections, Intravenous; Male; Predictive Value of Tests; Saliva	1996
Population pharmacokinetics of intravenous caffeine in neonates with apnea of prematurity. Clinical pharmacology and therapeutics, 1997, Volume: 61, Issue:6 Topics: Apnea; Caffeine; Chromatography, High Pressure Liquid; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Male; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Single-Blind Method	1997
Comparison of the effects of theophylline and caffeine on serum erythropoietin concentration in premature infants. European journal of pediatrics, 1998, Volume: 157, Issue:5 Topics: Anemia; Apnea; Caffeine; Erythropoietin; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline	1998
Low-dose doxapram for treatment of apnoea following early weaning in very low birthweight infants: a randomized, double-blind study. Acta paediatrica (Oslo, Norway : 1992), 1998, Volume: 87, Issue:11 Topics: Apnea; Blood Pressure; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Doxapram; Humans; Infant, Newborn; Infant, Very Low Birth Weight; Infusions, Intravenous; Respiratory System Agents; Treatment Outcome; Ventilator Weaning	1998
Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants. Biology of the neonate, 1999, Volume: 76, Issue:4 Topics: Apnea; Birth Weight; Bradycardia; Caffeine; Doxapram; Drug Resistance; Gestational Age; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infusions, Intravenous; Intubation, Gastrointestinal; Oxygen; Respiratory System Agents	1999
Caffeine citrate for the treatment of apnea of prematurity: a double-blind, placebo-controlled study. Pharmacotherapy, 2000, Volume: 20, Issue:6 Topics: Apnea; Caffeine; Citrates; Double-Blind Method; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Male	2000
Brain hemodynamic changes in preterm infants after maintenance dose caffeine and aminophylline treatment. Biology of the neonate, 2000, Volume: 78, Issue:1 Topics: Aminophylline; Apnea; Birth Weight; Blood Flow Velocity; Blood Volume; Caffeine; Central Nervous System Stimulants; Cerebrovascular Circulation; Electron Transport Complex IV; Gestational Age; Hemoglobins; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Oxygen; Oxyhemoglobins; Ultrasonography, Doppler	2000
[Pharmacologic study of monohydrated caffeine in the treatment of apnoea of premature infant]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2003, Volume: 10, Issue:6 Topics: Administration, Oral; Apnea; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Infant, Premature; Male; Prospective Studies	2003
[Monohydrated caffeine: which dosage is effective in the treatment of apnea of prematurity?]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2003, Volume: 10, Issue:8 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Infant, Premature; Treatment Outcome	2003
Olfactory stimulation prevents apnea in premature newborns. Pediatrics, 2005, Volume: 115, Issue:1 Topics: Apnea; Aromatherapy; Bradycardia; Caffeine; Central Nervous System Stimulants; Combined Modality Therapy; Doxapram; Drug Therapy, Combination; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Odorants; Physical Stimulation; Respiratory System Agents; Smell	2005
Effects of a divided high loading dose of caffeine on circulatory variables in preterm infants. Archives of disease in childhood. Fetal and neonatal edition, 2006, Volume: 91, Issue:1 Topics: Anterior Cerebral Artery; Apnea; Blood Flow Velocity; Caffeine; Carotid Artery, Internal; Celiac Artery; Central Nervous System Stimulants; Cerebrovascular Circulation; Drug Administration Schedule; Humans; Infant, Newborn; Infant, Premature; Intestines; Mesenteric Artery, Superior; Regional Blood Flow; Vascular Resistance	2006
Caffeine therapy for apnea of prematurity. The New England journal of medicine, 2006, May-18, Volume: 354, Issue:20 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Combined Modality Therapy; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Logistic Models; Male; Oxygen Inhalation Therapy; Respiration, Artificial; Weight Gain	2006
Long-term effects of caffeine therapy for apnea of prematurity. The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19 Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Developmental Disabilities; Epilepsy; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Logistic Models; Male; Odds Ratio; Retinopathy of Prematurity; Survival Rate	2007
Caffeine citrate treatment for extremely premature infants with apnea: population pharmacokinetics, absolute bioavailability, and implications for therapeutic drug monitoring. Therapeutic drug monitoring, 2008, Volume: 30, Issue:6 Topics: Apnea; Biological Availability; Caffeine; Central Nervous System Stimulants; Citrates; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Infant, Newborn; Infant, Premature; Male	2008
Caffeine versus theophylline for apnea of prematurity: a randomised controlled trial. Journal of paediatrics and child health, 2009, Volume: 45, Issue:10 Topics: Apnea; Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Drug Therapy, Combination; Greece; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Secondary Prevention; Theophylline	2009
Caffeine for Apnea of Prematurity trial: benefits may vary in subgroups. The Journal of pediatrics, 2010, Volume: 156, Issue:3 Topics: Apnea; Caffeine; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Oxygen Inhalation Therapy; Xanthines	2010
Survival without disability to age 5 years after neonatal caffeine therapy for apnea of prematurity. JAMA, 2012, Jan-18, Volume: 307, Issue:3 Topics: Apnea; Blindness; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Child Development; Child, Preschool; Cognition Disorders; Deafness; Developmental Disabilities; Female; Follow-Up Studies; Humans; Incidence; Infant; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Odds Ratio; Survival Analysis; Treatment Outcome	2012
The effects of caffeine on heart rate variability in newborns with apnea of prematurity. Journal of perinatology : official journal of the California Perinatal Association, 2014, Volume: 34, Issue:8 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Female; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Prospective Studies	2014
Reduction in developmental coordination disorder with neonatal caffeine therapy. The Journal of pediatrics, 2014, Volume: 165, Issue:2 Topics: Apnea; Caffeine; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Motor Skills Disorders; Treatment Outcome	2014
Long-term effects of caffeine therapy for apnea of prematurity on sleep at school age. American journal of respiratory and critical care medicine, 2014, Oct-01, Volume: 190, Issue:7 Topics: Actigraphy; Apnea; Caffeine; Central Nervous System Stimulants; Child; Child, Preschool; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Parents; Polysomnography; Prospective Studies; Sleep; Sleep Wake Disorders; Surveys and Questionnaires; Time	2014
High versus low-dose caffeine for apnea of prematurity: a randomized controlled trial. European journal of pediatrics, 2015, Volume: 174, Issue:7 Topics: Airway Extubation; Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Dose-Response Relationship, Drug; Double-Blind Method; Egypt; Female; Hospital Mortality; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Pilot Projects; Prospective Studies; Respiration, Artificial; Tachycardia	2015
Apnea of prematurity and caffeine pharmacokinetics: potential impact on hospital discharge. Journal of perinatology : official journal of the California Perinatal Association, 2016, Volume: 36, Issue:2 Topics: Apnea; Caffeine; Drug Monitoring; Female; Gestational Age; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Male; Outcome Assessment, Health Care; Patient Discharge; Purinergic P1 Receptor Antagonists; Time Factors; Withholding Treatment	2016
[Clinical effectiveness of different doses of caffeine for primary apnea in preterm infants]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2016, Volume: 54, Issue:1 Topics: Apnea; Birth Weight; Caffeine; Citrates; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Pregnancy; Treatment Outcome	2016
[Effect of caffeine citrate on early pulmonary function in preterm infants with apnea]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2016, Volume: 18, Issue:3 Topics: Aminophylline; Apnea; Caffeine; Citrates; Continuous Positive Airway Pressure; Female; Humans; Infant, Newborn; Infant, Premature; Lung; Male	2016
Caffeine Administration to Prevent Apnea in Very Premature Infants. Pediatrics and neonatology, 2016, Volume: 57, Issue:5 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Female; Gestational Age; Humans; Infant, Extremely Premature; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; Male	2016
Caffeine for the Treatment of Apnea in Bronchiolitis: A Randomized Trial. The Journal of pediatrics, 2016, Volume: 177 Topics: Apnea; Bronchiolitis; Caffeine; Citrates; Double-Blind Method; Female; Humans; Infant; Male	2016
[Effect of early caffeine treatment on the need for respirator therapy in preterm infants with respiratory distress syndrome]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2016, Volume: 18, Issue:12 Topics: Apnea; Caffeine; Female; Humans; Infant; Infant, Newborn; Male; Prospective Studies; Respiratory Distress Syndrome, Newborn; Ventilators, Mechanical	2016
Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity: An 11-Year Follow-up of the CAP Randomized Clinical Trial. JAMA pediatrics, 2017, 06-01, Volume: 171, Issue:6 Topics: Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Child Behavior Disorders; Child Development; Citrates; Developmental Disabilities; Double-Blind Method; Educational Status; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Male; Motor Disorders	2017
Comparative Efficacy and Safety of Caffeine and Aminophylline for Apnea of Prematurity in Preterm (≤34 weeks) Neonates: A Randomized Controlled Trial. Indian pediatrics, 2017, Apr-15, Volume: 54, Issue:4 Topics: Aminophylline; Apnea; Caffeine; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male	2017
Long-term neurodevelopment outcome of caffeine versus aminophylline therapy for apnea of prematurity. Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:4 Topics: Aminophylline; Apnea; Caffeine; Child Development; Cognition Disorders; Developmental Disabilities; Female; Hearing Disorders; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Language Development Disorders; Male; Motor Disorders; Purinergic P1 Receptor Antagonists; Survival Rate; Time Factors; Vision Disorders	2017
Neurobehavioral Outcomes 11 Years After Neonatal Caffeine Therapy for Apnea of Prematurity. Pediatrics, 2018, Volume: 141, Issue:5 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Child; Child Development; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Male; Motor Skills; Psychomotor Performance; Spatial Processing; Visual Perception	2018
Acute hemodynamic effects of methylxanthine therapy in preterm neonates: Effect of variations in subgroups. Journal of tropical pediatrics, 2019, 06-01, Volume: 65, Issue:3 Topics: Aminophylline; Apnea; Caffeine; Dose-Response Relationship, Drug; Echocardiography; Female; Gestational Age; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Treatment Outcome; Ventilator Weaning; Xanthines	2019
Influence of prevention of caffeine citrate on cytokine profile and bronchopulmonary dysplasia in preterm infants with apnea. Minerva pediatrica, 2020, Volume: 72, Issue:2 Topics: Apnea; Birth Weight; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Citrates; Drug Administration Schedule; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Infusions, Intravenous; Interleukin-6; Interleukin-8; Length of Stay; Maintenance Chemotherapy; Male; Respiration, Artificial; Time Factors	2020
[Clinical effect and safety of different maintenance doses of caffeine citrate in treatment of apnea in very low birth weight preterm infants: a prospective randomized controlled trial]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2019, Volume: 21, Issue:6 Topics: Apnea; Caffeine; Child; Citrates; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Prospective Studies	2019
Caffeine citrate maintenance doses effect on extubation and apnea postventilation in preterm infants. Pediatric pulmonology, 2020, Volume: 55, Issue:10 Topics: Airway Extubation; Apnea; Caffeine; Citrates; Continuous Positive Airway Pressure; Double-Blind Method; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Male	2020
[Comparison of the efficacy of domestic and imported caffeine citrate in the treatment of apnea in preterm infants: a prospective randomized double-blind controlled trial]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2020, Volume: 22, Issue:7 Topics: Apnea; Caffeine; Citrates; Double-Blind Method; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Prospective Studies	2020
Early application of caffeine improves white matter development in very preterm infants. Respiratory physiology & neurobiology, 2020, Volume: 281 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Child Development; Diffusion Tensor Imaging; Female; Gray Matter; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature, Diseases; Magnetic Resonance Imaging; Male; Outcome Assessment, Health Care; White Matter	2020
(Rad 8)Caffeine prophylaxis to improve intermittent hypoxaemia in infants born late preterm: a randomised controlled dosage trial (Latte Dosage Trial). BMJ open, 2020, 10-20, Volume: 10, Issue:10 Topics: Apnea; Caffeine; Female; Humans; Hypoxia; Infant; Infant, Newborn; Infant, Premature; New Zealand; Pregnancy	2020
Duration of Caffeine for Apnea of Prematurity-A Randomized Controlled Trial. Indian journal of pediatrics, 2021, Volume: 88, Issue:12 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2021
Prophylactic versus therapeutic caffeine for apnea of prematurity: a randomized controlled trial. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:25 Topics: Apnea; Caffeine; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Oxygen	2022
A Randomized Controlled Trial Comparing Two Doses of Caffeine for Apnoea in Prematurity. International journal of environmental research and public health, 2021, 04-23, Volume: 18, Issue:9 Topics: Apnea; Caffeine; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2021
Effect of Prophylactic Caffeine on Noninvasive Respiratory Support in Preterm Neonates Weighing 1250-2000 g: A Randomized Controlled Trial. Archives of Iranian medicine, 2022, 02-01, Volume: 25, Issue:2 Topics: Apnea; Caffeine; Continuous Positive Airway Pressure; Humans; Infant; Infant, Newborn; Infant, Premature; Respiratory Distress Syndrome, Newborn	2022
Enteral and Parenteral Treatment with Caffeine for Preterm Infants in the Delivery Room: A Randomised Trial. Paediatric drugs, 2023, Volume: 25, Issue:1 Topics: Apnea; Caffeine; Delivery Rooms; Gestational Age; Humans; Infant, Newborn; Infant, Premature	2023

Other Studies

188 other study(ies) available for caffeine and apnea

Article	Year
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium	1999
Efficacy of caffeine in treatment of apnea in the low-birth-weight infant. The Journal of pediatrics, 1977, Volume: 90, Issue:3 Topics: Apnea; Caffeine; Carbon Dioxide; Drug Evaluation; Humans; Hydrogen-Ion Concentration; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases	1977
Biotransformation of theophylline to caffeine in premature newborn. Lancet (London, England), 1978, Dec-02, Volume: 2, Issue:8101 Topics: Administration, Oral; Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1978
Methylation of theophylline to caffeine in premature infants. Lancet (London, England), 1979, Apr-14, Volume: 1, Issue:8120 Topics: Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Methylation; Theophylline; Xanthines	1979
Sequelae of caffeine treatment in preterm infants with apnea. The Journal of pediatrics, 1979, Volume: 94, Issue:1 Topics: Apnea; Caffeine; Child Development; Female; Follow-Up Studies; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; Intermittent Positive-Pressure Ventilation; Male; Nervous System Diseases; Retinopathy of Prematurity	1979
Pharmacokinetic profile of caffeine in the premature newborn infant with apnea. The Journal of pediatrics, 1979, Volume: 94, Issue:4 Topics: Administration, Oral; Apnea; Caffeine; Half-Life; Humans; Infant, Newborn; Infant, Premature, Diseases; Infusions, Parenteral; Kinetics	1979
Plasma xanthine levels in low birthweight infants treated or not treated with theophylline. Archives of disease in childhood, 1979, Volume: 54, Issue:3 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Metabolic Clearance Rate; Milk, Human; Theophylline; Xanthines	1979
Metabolism of theophylline to caffeine in premature newborn infants. The Journal of pediatrics, 1979, Volume: 94, Issue:6 Topics: Adult; Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1979
Interconversion of theophylline and caffeine in newborn infants. The Journal of pediatrics, 1979, Volume: 94, Issue:6 Topics: Age Factors; Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theobromine; Theophylline; Xanthines	1979
Caffeine, a metabolite of theophylline during the treatment of apnea in the premature infant. The Journal of pediatrics, 1979, Volume: 94, Issue:6 Topics: Apnea; Caffeine; Half-Life; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Theophylline	1979
Relationship of plasma and CSF concentrations of caffeine in neonates with apnea. The Journal of pediatrics, 1979, Volume: 95, Issue:4 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases	1979
Metabolism of theophylline to caffeine in human fetal liver. Science (New York, N.Y.), 1979, Dec-14, Volume: 206, Issue:4424 Topics: Apnea; Biotransformation; Caffeine; Cells, Cultured; Gestational Age; Humans; Infant, Newborn; Liver; Methylation; Theophylline	1979
Apneic spells and transcutaneous PO2: treatment with caffeine, 19-year follow-up. Birth defects original article series, 1979, Volume: 15, Issue:4 Topics: Apnea; Blood Gas Analysis; Blood Pressure; Caffeine; Diagnosis, Differential; Follow-Up Studies; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Oxygen; Partial Pressure; Skin	1979
Micro-method for the determination of caffeine and theophylline allowing direct application of biological fluids to thin-layer chromatography plates. Journal of chromatography, 1978, Jul-01, Volume: 146, Issue:1 Topics: Apnea; Caffeine; Child; Child, Preschool; Chromatography, Thin Layer; Female; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Male; Microchemistry; Saliva; Theophylline	1978
The xanthine treatment of apnea of prematurity. Pediatrics, 1975, Volume: 55, Issue:5 Topics: Aminophylline; Apnea; Bradycardia; Caffeine; Humans; Hypoxia; Infant, Newborn; Infant, Premature, Diseases; Prognosis; Theophylline; Xanthines	1975
[Effects of coffee on the respiratory system]. Revue des maladies respiratoires, 1992, Volume: 9, Issue:6 Topics: Adult; Apnea; Bronchial Neoplasms; Caffeine; Coffee; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lung Diseases, Obstructive; Male; Occupational Diseases; Pregnancy; Respiratory Hypersensitivity; Respiratory System; Risk Factors; Smoking	1992
Effectiveness and side effects of two different doses of caffeine in preventing apnea in premature infants. Therapeutic drug monitoring, 1992, Volume: 14, Issue:1 Topics: Apnea; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theobromine; Theophylline	1992
Severe caffeine intoxication in a preterm neonate. European journal of pediatrics, 1992, Volume: 151, Issue:6 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male	1992
Percutaneous caffeine application in the treatment of neonatal apnoea. European journal of pediatrics, 1991, Volume: 150, Issue:8 Topics: Administration, Cutaneous; Apnea; Caffeine; Chromatography, High Pressure Liquid; Citrates; Drug Combinations; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature	1991
[Importance of monitoring theophylline and caffeine plasma levels in the management of neonatal apnea]. Anales espanoles de pediatria, 1991, Volume: 34, Issue:4 Topics: Apnea; Asphyxia Neonatorum; Caffeine; Humans; Infant, Newborn; Monitoring, Physiologic; Theophylline	1991
[Caffeine in the treatment of apnea in premature infants]. Archives francaises de pediatrie, 1990, Volume: 47, Issue:10 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases	1990
[Efficacy of percutaneous caffeine in the treatment of apnea in the premature infant]. Archives francaises de pediatrie, 1990, Volume: 47, Issue:3 Topics: Administration, Cutaneous; Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Massage	1990
Cardiovascular effects of caffeine therapy in preterm infants. American journal of diseases of children (1960), 1990, Volume: 144, Issue:10 Topics: Apnea; Blood Pressure; Caffeine; Cardiac Output; Heart; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Stroke Volume; Ventilator Weaning	1990
Does caffeine affect cerebral blood flow in the preterm infant? Acta paediatrica Scandinavica, 1989, Volume: 78, Issue:2 Topics: Apnea; Blood Gas Monitoring, Transcutaneous; Caffeine; Cerebrovascular Circulation; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Ultrasonography	1989
Caffeine citrate in the NICU. Neonatal network : NN, 1989, Volume: 7, Issue:5 Topics: Apnea; Caffeine; Citrates; Drug Combinations; Humans; Infant, Newborn; Infant, Premature, Diseases; Intensive Care Units, Neonatal	1989
Caffeine citrate. Pointers in practical pharmacology. Neonatal network : NN, 1989, Volume: 7, Issue:6 Topics: Apnea; Caffeine; Citrates; Drug Combinations; Humans; Infant, Newborn; Infant, Premature, Diseases	1989
Transplacentally acquired caffeine and the occurrence of apnea, bradycardia, and periodic breathing in preterm infants: preliminary communication. Pediatric pulmonology, 1989, Volume: 7, Issue:2 Topics: Apnea; Bradycardia; Caffeine; Cheyne-Stokes Respiration; Chromatography, High Pressure Liquid; Female; Fetal Blood; Humans; Infant, Newborn; Infant, Premature; Maternal-Fetal Exchange; Pregnancy; Respiration; Respiration Disorders; Respiratory Function Tests	1989
Low-dose doxapram for apnoea of prematurity. Lancet (London, England), 1986, Apr-05, Volume: 1, Issue:8484 Topics: Apnea; Caffeine; Doxapram; Drug Therapy, Combination; Humans; Infant, Newborn; Infant, Premature, Diseases; Pilot Projects; Recurrence	1986
Oral versus intramuscular loading of caffeine in idiopathic apnoea of prematurity. European journal of pediatrics, 1988, Volume: 148, Issue:3 Topics: Administration, Oral; Apnea; Blood Glucose; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Injections, Intramuscular; Insulin	1988
Maturation of caffeine N-demethylation in infancy: a study using the 13CO2 breath test. Pediatric research, 1988, Volume: 23, Issue:6 Topics: Apnea; Breath Tests; Caffeine; Carbon Dioxide; Chromatography, High Pressure Liquid; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Oxidoreductases, N-Demethylating; Pierre Robin Syndrome	1988
Change of plasma half-life of caffeine during caffeine therapy for apnea in premature infants. Acta paediatrica Japonica : Overseas edition, 1987, Volume: 29, Issue:4 Topics: Apnea; Caffeine; Half-Life; Humans; Infant, Newborn; Infant, Premature	1987
Developmental changes of caffeine elimination in infancy. Developmental pharmacology and therapeutics, 1988, Volume: 11, Issue:5 Topics: Aging; Apnea; Caffeine; Drug Administration Schedule; Gestational Age; Half-Life; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases	1988
The relationship between theophylline, caffeine and heart rate in neonates. Annals of clinical biochemistry, 1988, Volume: 25 ( Pt 4) Topics: Aminophylline; Apnea; Caffeine; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Theophylline; Xanthines	1988
Maturation of caffeine metabolic pathways in infancy. Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:2 Topics: Acetylation; Administration, Oral; Adult; Age Factors; Apnea; Caffeine; Chromatography, High Pressure Liquid; Citrates; Drug Combinations; Female; Humans; Hydroxylation; Infant; Infant, Newborn; Infant, Premature; Male; Pierre Robin Syndrome; Time Factors; Uracil; Xanthines	1988
Apnea in infancy: pathophysiology, diagnosis, and treatment. New York state journal of medicine, 1986, Volume: 86, Issue:2 Topics: Aminophylline; Apnea; Caffeine; Chemoreceptor Cells; Home Nursing; Humans; Infant; Infant, Newborn; Monitoring, Physiologic; Pulmonary Gas Exchange; Sudden Infant Death; Theophylline	1986
Simultaneous administration of caffeine and phenobarbitone in infants with apnea. The Journal of pediatrics, 1987, Volume: 110, Issue:4 Topics: Apnea; Caffeine; Drug Therapy, Combination; Half-Life; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital	1987
[Xanthines in apnea of premature infants. Influence on gastroesophageal reflux]. Archives francaises de pediatrie, 1987, Volume: 44, Issue:5 Topics: Apnea; Caffeine; Gastroesophageal Reflux; Humans; Infant, Newborn; Infant, Premature, Diseases; Xanthines	1987
Infant apnea. Pediatric clinics of North America, 1986, Volume: 33, Issue:3 Topics: Airway Obstruction; Apnea; Bradycardia; Caffeine; Cardiography, Impedance; Home Nursing; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Monitoring, Physiologic; Risk; Sleep; Sudden Infant Death; Theophylline; Xanthines	1986
Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study. Pediatrics, 1986, Volume: 78, Issue:1 Topics: Apnea; Birth Weight; Caffeine; Female; Humans; Infant, Newborn; Maternal Age; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; Smoking; Surveys and Questionnaires	1986
Apnoea and seizures. Archives of disease in childhood, 1986, Volume: 61, Issue:8 Topics: Apnea; Caffeine; Electroencephalography; Female; Humans; Infant; Male; Seizures	1986
Effect of caffeine on pneumogram and apnoea of infancy. Archives of disease in childhood, 1986, Volume: 61, Issue:9 Topics: Apnea; Caffeine; Citrates; Drug Combinations; Humans; Infant, Newborn; Infant, Premature, Diseases; Respiration; Time Factors	1986
[Peculiarities of drug therapy in childhood]. Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:11 Topics: Apnea; Biological Availability; Biotransformation; Caffeine; Child; Child, Preschool; Dexamethasone; Drug Therapy; Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature, Diseases; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Receptors, Drug; Theophylline; Tissue Distribution	1986
Delay in caffeine elimination in breast-fed infants. Pediatrics, 1987, Volume: 79, Issue:2 Topics: Apnea; Biological Availability; Bottle Feeding; Breast Feeding; Caffeine; Fatty Acids, Nonesterified; Female; Half-Life; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Lipase; Longitudinal Studies; Milk, Human; Prospective Studies	1987
Caffeine citrate: an alternative to theophylline for apnea in prematurity. Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:10 Topics: Apnea; Caffeine; Citrates; Drug Combinations; Humans; Infant, Newborn; Theophylline	1985
Maturational changes of caffeine concentrations and disposition in infancy during maintenance therapy for apnea of prematurity: influence of gestational age, hepatic disease, and breast-feeding. Pediatrics, 1985, Volume: 76, Issue:5 Topics: Aging; Apnea; Breast Feeding; Caffeine; Cholestasis; Citrates; Drug Combinations; Gestational Age; Half-Life; Hepatitis; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Liver; Longitudinal Studies; Prospective Studies	1985
[Resuscitation of the newborn]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Jun-08, Volume: 45, Issue:27 Topics: Acidosis, Respiratory; Apnea; Bicarbonates; Caffeine; Catheterization; Cyanosis; Equipment and Supplies, Hospital; Glucose; Heart Massage; Hernia, Diaphragmatic; Humans; Hypertonic Solutions; Hypoxia; Infant, Newborn; Intubation, Intratracheal; Laryngoscopy; Oxygen Inhalation Therapy; Pierre Robin Syndrome; Pulmonary Atelectasis; Respiration, Artificial; Resuscitation; Syncope; Tampons, Surgical; Umbilical Cord	1969
[Apnea periods in the premature infant]. Tijdschrift voor ziekenverpleging, 1974, Aug-27, Volume: 27, Issue:31 Topics: Apnea; Caffeine; Heart Rate; Humans; Infant, Newborn; Infant, Premature, Diseases; Monitoring, Physiologic; Oxygen Inhalation Therapy; Positive-Pressure Respiration; Resuscitation	1974
Use of caffeine in neonates. American journal of hospital pharmacy, 1984, Volume: 41, Issue:8 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Newborn, Diseases	1984
Ontogeny of human caffeine and theophylline metabolism. Developmental pharmacology and therapeutics, 1984, Volume: 7 Suppl 1 Topics: Adult; Aged; Apnea; Caffeine; Child; Child, Preschool; Half-Life; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Kinetics; Middle Aged; Theophylline	1984
Maternal coffee drinking and unusually high concentrations of caffeine in the newborn. Journal of toxicology. Clinical toxicology, 1984, Volume: 22, Issue:5 Topics: Apnea; Caffeine; Coffee; Female; Half-Life; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Pregnancy; Saliva	1984
Effect of caffeine on control of breathing in infantile apnea. The Journal of pediatrics, 1983, Volume: 103, Issue:6 Topics: Apnea; Caffeine; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Maximal Voluntary Ventilation; Pulmonary Ventilation; Respiration; Respiratory Function Tests; Sudden Infant Death	1983
T4 levels in methylxanthine-treated premature newborns. Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Retrospective Studies; Theophylline; Thyroid Gland; Thyrotropin; Thyroxine	1983
Interaction of caffeine and continuous distending airway pressure in neonatal apnea. American journal of perinatology, 1983, Volume: 1, Issue:1 Topics: Apnea; Caffeine; Combined Modality Therapy; Humans; Infant, Newborn; Infant, Premature, Diseases; Lung Volume Measurements; Male; Respiration, Artificial	1983
Effects of caffeine in the treatment of apnea. Canadian Medical Association journal, 1984, Apr-15, Volume: 130, Issue:8 Topics: Animals; Apnea; Caffeine; Cerebrovascular Circulation; Coronary Circulation; Humans; Infant, Newborn	1984
The metabolic effects of caffeine in the newborn infant. Pediatric pharmacology (New York, N.Y.), 1981, Volume: 1, Issue:3 Topics: Apnea; Blood Glucose; Caffeine; Catecholamines; Electrolytes; Heart Rate; Homeostasis; Humans; Infant, Newborn; Infant, Newborn, Diseases; Parenteral Nutrition	1981
Plasma theophylline and caffeine and plasma clearance of theophylline during theophylline treatment in the first year of life. European journal of clinical pharmacology, 1983, Volume: 24, Issue:3 Topics: Apnea; Caffeine; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline; Xanthines	1983
Plasma xanthine levels in premature infants treated for apnoea with theophylline. Journal of clinical and hospital pharmacy, 1983, Volume: 8, Issue:2 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Theophylline; Xanthines	1983
Apnea associated with theophylline withdrawal in a term neonate. American journal of diseases of children (1960), 1982, Volume: 136, Issue:1 Topics: Apnea; Caffeine; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Pregnancy; Substance Withdrawal Syndrome; Theophylline	1982
Pharmacokinetic aspects of caffeine in premature infants with apnoea. European journal of clinical pharmacology, 1982, Volume: 22, Issue:1 Topics: Apnea; Caffeine; Female; Half-Life; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Male	1982
Cross validation of serum to saliva relationships of caffeine, theophylline and total methylxanthines in neonates. Developmental pharmacology and therapeutics, 1982, Volume: 4, Issue:1-2 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Saliva; Theophylline; Xanthines	1982
[Use of caffeine in the treatment of apnea in premature infants]. Developmental pharmacology and therapeutics, 1982, Volume: 4 Suppl Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Theophylline; Time Factors	1982
Effect of serum caffeine level on pneumocardiogram of premature infants treated for apnea with theophylline. Medical hypotheses, 1982, Volume: 9, Issue:6 Topics: Apnea; Caffeine; Electrocardiography; False Negative Reactions; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Respiration; Theophylline	1982
Caffeine and theophylline: serum/CSF correlation in premature infants. The Journal of pediatrics, 1980, Volume: 96, Issue:6 Topics: Apnea; Blood-Brain Barrier; Caffeine; Chromatography, Liquid; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline; Xanthines	1980
Pharmacologic considerations in the therapy of neonatal apnea. Pediatric clinics of North America, 1981, Volume: 28, Issue:1 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Monitoring, Physiologic; Theophylline	1981
Relationship of dose and plasma concentrations of caffeine and ventilation in neonatal apnea. Seminars in perinatology, 1981, Volume: 5, Issue:4 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Kinetics; Respiration	1981
Methylxanthines in serum, saliva, and spinal fluid of premature infants. Seminars in perinatology, 1981, Volume: 5, Issue:4 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Kinetics; Saliva; Theophylline	1981
Adverse effects of caffeine and theophylline in the newborn infant. Seminars in perinatology, 1981, Volume: 5, Issue:4 Topics: Apnea; Asphyxia Neonatorum; Caffeine; Cardiovascular System; Central Nervous System; Digestive System; Hormones; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Kidney; Retina; Theophylline	1981
[Pharmacokinetics of theophylline and caffeine in premature infants with apnea (author's transl)]. Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1981, Volume: 129, Issue:12 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Protein Binding; Theophylline	1981
Use of salivary concentrations in the prediction of serum caffeine and theophylline concentrations in premature infants. The Journal of pediatrics, 1980, Volume: 96, Issue:3 Pt 1 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Regression Analysis; Saliva; Theophylline	1980
Simultaneous determination of theophylline and caffeine after extractive alkylation in small volumes of plasma by gas chromatography--mass spectrometry. Journal of chromatography, 1980, Nov-14, Volume: 221, Issue:1 Topics: Alkylation; Apnea; Caffeine; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Theophylline	1980
Plasma beta-endorphin concentration and xanthine treatment in apnea of prematurity. Clinical and investigative medicine. Medecine clinique et experimentale, 1993, Volume: 16, Issue:3 Topics: Apnea; beta-Endorphin; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Xanthine; Xanthines	1993
Individualizing aminophylline doses in premature infants using bioelectrical impedance: a non-invasive approach. Journal of paediatrics and child health, 1993, Volume: 29, Issue:2 Topics: Aminophylline; Apnea; Caffeine; Electric Impedance; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Metabolic Clearance Rate; Models, Biological; Regression Analysis	1993
Aminophylline versus caffeine citrate... Acta paediatrica (Oslo, Norway : 1992), 1995, Volume: 84, Issue:10 Topics: Aminophylline; Apnea; Bradycardia; Caffeine; Cardiotonic Agents; Citrates; Clinical Trials as Topic; Drug Combinations; Humans; Infant, Newborn; Infant, Premature, Diseases; Placebos; Research Design	1995
Apnea following spinal anaesthesia in two former pre-term infants. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:10 Topics: Age Factors; Anesthesia, Spinal; Anesthetics, Local; Apnea; Benzoates; Bradycardia; Caffeine; Central Nervous System Stimulants; Drug Combinations; Female; Follow-Up Studies; Hernia, Inguinal; Humans; Infant; Infant, Newborn; Infant, Premature; Intraoperative Complications; Male; Nerve Block; Tetracaine; Time Factors	1998
The effect of theophylline on apnoea and hypoxaemic episodes in the premature neonate during the 1st 3 days after birth. Annals of tropical paediatrics, 1998, Volume: 18, Issue:3 Topics: Apnea; Blood Pressure; Bradycardia; Bronchodilator Agents; Caffeine; Female; Gestational Age; Humans; Hypoxia; Infant, Newborn; Infant, Small for Gestational Age; Male; Oxygen; Theophylline	1998
Caffeine overdose in a premature infant: clinical course and pharmacokinetics. Anaesthesia and intensive care, 1999, Volume: 27, Issue:3 Topics: Age Factors; Apnea; Caffeine; Central Nervous System Stimulants; Drug Overdose; Female; Humans; Infant, Newborn; Infant, Premature; Medication Errors; Models, Theoretical; Pharmacokinetics	1999
Caffeine in the treatment of apnea associated with respiratory syncytial virus infection in neonates and infants. Southern medical journal, 2000, Volume: 93, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Critical Care; Data Interpretation, Statistical; Follow-Up Studies; Humans; Infant; Infant, Newborn; Injections, Intravenous; Recurrence; Respiratory Syncytial Virus Infections; Respiratory Tract Infections; Retrospective Studies; Time Factors	2000
Prediction of postdischarge complications by predischarge event recordings in infants with apnea of prematurity. Journal of perinatology : official journal of the California Perinatal Association, 2000, Volume: 20, Issue:2 Topics: Apnea; Caffeine; Citrates; Drug Combinations; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Monitoring, Ambulatory; Predictive Value of Tests	2000
Pharmacokinetics of theophylline and caffeine after intravenous administration of aminophylline to premature neonates in Korea. Research communications in molecular pathology and pharmacology, 1999, Volume: 105, Issue:1-2 Topics: Aminophylline; Apnea; Caffeine; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Korea; Male; Theophylline	1999
Effect of caffeine on oxygen consumption and metabolic rate in very low birth weight infants with idiopathic apnea. Pediatrics, 2001, Volume: 107, Issue:4 Topics: Apnea; Body Weight; Caffeine; Energy Metabolism; Humans; Infant, Newborn; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Oxygen Consumption	2001
Postoperative recovery after inguinal herniotomy in ex-premature infants and the use of caffeine. British journal of anaesthesia, 2002, Volume: 88, Issue:2 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Hernia, Inguinal; Humans; Infant; Infant, Newborn; Infant, Premature; Postoperative Complications	2002
Caffeine in apnoeic Asian neonates: a sparse data analysis. British journal of clinical pharmacology, 2002, Volume: 54, Issue:1 Topics: Apnea; Asia; Body Weight; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Citrates; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Infant, Newborn; Infusions, Intravenous; Injections, Intravenous; Male; Statistics as Topic	2002
[IS SUBARACHNOID ADMINISTRATION OF CAFFEINE IN APNEA DURING HIGH SPINAL ANESTHESIA?]. Khirurgiia, 1963, Volume: 39 Topics: Anesthesia; Anesthesia, Spinal; Anesthesiology; Apnea; Caffeine; Humans	1963
[PRINCIPAL HAZARDS OF SPINAL ANESTHESIA AND METHODS FOR THEIR ELIMINATION]. Vestnik khirurgii imeni I. I. Grekova, 1963, Volume: 91 Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesia, Spinal; Anesthesiology; Apnea; Blood Pressure; Blood Pressure Determination; Caffeine; Ephedrine; Humans	1963
Apnoeas in bronchiolitis: is there a role for caffeine? Archives of disease in childhood, 2005, Volume: 90, Issue:4 Topics: Apnea; Bronchiolitis; Caffeine; Central Nervous System Stimulants; Humans; Infant	2005
Long-term consequences of neonatal caffeine on ventilation, occurrence of apneas, and hypercapnic chemoreflex in male and female rats. Pediatric research, 2006, Volume: 59, Issue:4 Pt 1 Topics: Animals; Animals, Newborn; Apnea; Caffeine; Central Nervous System Stimulants; Female; Humans; Hypercapnia; Male; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Reflex; Stress, Physiological	2006
Caffeine for apnea of prematurity. The New England journal of medicine, 2006, May-18, Volume: 354, Issue:20 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Respiration, Artificial	2006
Correlation between plasma and urinary caffeine levels in preterm infants. Journal of perinatal medicine, 2006, Volume: 34, Issue:4 Topics: Apnea; Caffeine; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Male	2006
[Caffeine citrate utilization for treatment of apnea in French neonatal units]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:10 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Utilization; France; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Surveys and Questionnaires	2006
[Apnea of prematurity: risk factors and ambulatory treatment with caffeine citrate]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:10 Topics: Ambulatory Care; Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Citrates; Continuous Positive Airway Pressure; Female; Gastroesophageal Reflux; Humans; Hypotension; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Multivariate Analysis; Pregnancy; Pregnancy, Multiple; Retrospective Studies; Risk Factors	2006
Caffeine for apnea of prematurity. The New England journal of medicine, 2006, Aug-31, Volume: 355, Issue:9 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Diuresis; Growth; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Weight Gain	2006
Caffeine for apnea of prematurity. The New England journal of medicine, 2006, Aug-31, Volume: 355, Issue:9 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Ductus Arteriosus, Patent; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Oxygen Inhalation Therapy	2006
Serum caffeine concentrations in preterm neonates. American journal of perinatology, 2007, Volume: 24, Issue:1 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Cross-Sectional Studies; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Male; Retrospective Studies	2007
Therapeutic drug monitoring for caffeine in preterm neonates: an unnecessary exercise? Pediatrics, 2007, Volume: 119, Issue:5 Topics: Apnea; Caffeine; Citrates; Drug Monitoring; Humans; Infant, Newborn; Infant, Premature	2007
On the caffeination of prematurity. The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Developmental Disabilities; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Retinopathy of Prematurity; Weight Gain	2007
Enhancement of the breathing frequency response to hypoxia by neonatal caffeine treatment in adult male rats: the role of testosterone. Respiratory physiology & neurobiology, 2009, Feb-28, Volume: 165, Issue:2-3 Topics: Age Factors; Animals; Animals, Newborn; Apnea; Caffeine; Central Nervous System Stimulants; Hypoxia; Male; Orchiectomy; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Sex Characteristics; Testosterone	2009
Acute hemodynamic effects of caffeine administration in premature infants. Journal of perinatology : official journal of the California Perinatal Association, 2009, Volume: 29, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Hemodynamics; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Prospective Studies	2009
Caffeine reduces apnea frequency and enhances ventilatory long-term facilitation in rat pups raised in chronic intermittent hypoxia. Pediatric research, 2010, Volume: 68, Issue:2 Topics: Animals; Animals, Newborn; Apnea; Caffeine; Central Nervous System Stimulants; Female; Humans; Hypoxia; Infant, Newborn; Male; Plethysmography, Whole Body; Pulmonary Ventilation; Random Allocation; Rats; Respiratory Mechanics	2010
Orphan drugs. Viridian Pharma replies. BMJ (Clinical research ed.), 2010, Dec-07, Volume: 341 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Drug Costs; Humans; Infant, Newborn; Orphan Drug Production	2010
Economic evaluation of caffeine for apnea of prematurity. Pediatrics, 2011, Volume: 127, Issue:1 Topics: Apnea; Caffeine; Cost-Benefit Analysis; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Retrospective Studies	2011
Archimedes: Does caffeine treatment for apnoea of prematurity improve neurodevelopmental outcome in later life? Archives of disease in childhood, 2011, Volume: 96, Issue:8 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Developmental Disabilities; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Research Design	2011
Alteration of carotid body chemoreflexes after neonatal intermittent hypoxia and caffeine treatment in rat pups. Respiratory physiology & neurobiology, 2011, Aug-15, Volume: 177, Issue:3 Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Apnea; Body Temperature; Body Weight; Caffeine; Carotid Body; Central Nervous System Stimulants; Chemoreceptor Cells; Domperidone; Dopamine; Dopamine Antagonists; Female; Hypoxia; Male; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reflex; Time Factors; Ventilation	2011
What are the main research findings during the last 5 years that have changed my approach to clinical practice? Archives of disease in childhood. Fetal and neonatal edition, 2013, Volume: 98, Issue:1 Topics: Apnea; Caffeine; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Extremely Premature; Infant, Newborn; Neonatology; Oximetry; Practice Patterns, Physicians'; Retinopathy of Prematurity; Vascular Endothelial Growth Factor A	2013
Neuroprotection for premature infants?: another perspective on caffeine. JAMA, 2012, Jan-18, Volume: 307, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Cognition Disorders; Female; Humans; Infant, Premature; Infant, Very Low Birth Weight; Male	2012
Caffeine therapy in neonatal intensive care. Irish medical journal, 2012, Volume: 105, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Child Development; Child, Preschool; Humans; Infant; Infant, Newborn; Intensive Care, Neonatal; Premature Birth	2012
Caffeine as treatment for bronchiolitis-related apnoea. Journal of paediatrics and child health, 2012, Volume: 48, Issue:7 Topics: Apnea; Bronchiolitis; Caffeine; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Retrospective Studies; Treatment Outcome	2012
Dried blood spots and sparse sampling: a practical approach to estimating pharmacokinetic parameters of caffeine in preterm infants. British journal of clinical pharmacology, 2013, Volume: 75, Issue:3 Topics: Apnea; Birth Weight; Caffeine; Central Nervous System Agents; Dried Blood Spot Testing; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Male; Models, Theoretical; Prospective Studies; Specimen Handling	2013
Effects of caffeine and/or nasal CPAP treatment on laryngeal chemoreflexes in preterm lambs. Journal of applied physiology (Bethesda, Md. : 1985), 2013, Mar-01, Volume: 114, Issue:5 Topics: Animals; Animals, Newborn; Apnea; Arterial Pressure; Bradycardia; Caffeine; Continuous Positive Airway Pressure; Female; Larynx; Male; Muscles; Pregnancy; Reflex; Sheep	2013
Influence of age, body temperature, GABAA receptor inhibition and caffeine on the Hering-Breuer inflation reflex in unanesthetized rat pups. Respiratory physiology & neurobiology, 2013, Mar-01, Volume: 186, Issue:1 Topics: Aging; Animals; Animals, Newborn; Apnea; Body Temperature; Caffeine; Central Nervous System Stimulants; GABA-A Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adenosine A2; Receptors, GABA-A; Reflex; Respiration; Respiratory Physiological Phenomena	2013
The use of caffeine for the treatment of apnea of prematurity and bradycardia in a holoprosencephalic child with cleft lip and palate. Journal of clinical anesthesia, 2013, Volume: 25, Issue:8 Topics: Apnea; Bradycardia; Caffeine; Central Nervous System Stimulants; Citrates; Cleft Lip; Cleft Palate; Female; Holoprosencephaly; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Postoperative Complications	2013
Methylxanthine use for apnea of prematurity among an international cohort of neonatologists. Journal of neonatal-perinatal medicine, 2013, Volume: 6, Issue:3 Topics: Apnea; Australia; Caffeine; Cross-Sectional Studies; Female; Health Knowledge, Attitudes, Practice; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lebanon; Male; Neonatology; Surveys and Questionnaires; Thailand; United States; Xanthines	2013
Safety profile comparison between extemporaneous and a licensed preparation of caffeine citrate in preterm infants with apnea of prematurity. Neonatology, 2014, Volume: 105, Issue:2 Topics: Apnea; Caffeine; Chemistry, Pharmaceutical; Citrates; Drug-Related Side Effects and Adverse Reactions; Female; Germany; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Licensure; Longitudinal Studies; Male	2014
Effects of caffeine treatment for apnea of prematurity on cortical speech-sound differentiation in preterm infants. Journal of child neurology, 2015, Volume: 30, Issue:3 Topics: Acoustic Stimulation; Analysis of Variance; Apnea; Brain Mapping; Caffeine; Central Nervous System Stimulants; Cerebral Cortex; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Female; Humans; Infant; Infant, Premature; Male; Phonetics	2015
Standardizing documentation and the clinical approach to apnea of prematurity reduces length of stay, improves staff satisfaction, and decreases hospital cost. Joint Commission journal on quality and patient safety, 2014, Volume: 40, Issue:6 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Documentation; Gestational Age; Hospital Costs; Humans; Infant, Premature; Inservice Training; Job Satisfaction; Length of Stay; Monitoring, Ambulatory; Patient Discharge; Prospective Studies; Quality of Health Care	2014
Current management of apnea in premature infants: is caffeine the magic bullet? Early human development, 2014, Volume: 90 Suppl 2 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Respiration, Artificial; Respiratory System Agents	2014
Former preterm infants, caffeine was good for you, but now beware of snoring! American journal of respiratory and critical care medicine, 2014, Oct-01, Volume: 190, Issue:7 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Female; Humans; Infant, Premature, Diseases; Male; Sleep; Sleep Wake Disorders	2014
Effect of caffeine on preterm infants' cerebral cortical activity: an observational study. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:17 Topics: Apnea; Blood Pressure; Caffeine; Cerebral Cortex; Electroencephalography; Female; Gestational Age; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Intensive Care, Neonatal; Length of Stay; Male; Oxygen; Prospective Studies; Respiratory Physiological Phenomena; Respiratory System; Sleep; Wakefulness	2015
Association of early caffeine administration and neonatal outcomes in very preterm neonates. JAMA pediatrics, 2015, Volume: 169, Issue:1 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Canada; Ductus Arteriosus, Patent; Gestational Age; Humans; Infant; Infant Mortality; Infant, Extremely Premature; Infant, Newborn; Retrospective Studies; Time Factors; Treatment Outcome	2015
[Comparison of caffeine citrate and aminophylline for treating primary apnea in premature infants]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2014, Volume: 16, Issue:11 Topics: Aminophylline; Apnea; Caffeine; Citrates; Female; Humans; Infant, Newborn; Infant, Premature; Male; Retrospective Studies	2014
Neonatal caffeine therapy and sleep: important findings to guide new approaches and reduce concerns. American journal of respiratory and critical care medicine, 2014, Dec-01, Volume: 190, Issue:11 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Female; Humans; Infant, Premature, Diseases; Male; Sleep; Sleep Wake Disorders	2014
Reply: neonatal caffeine therapy and sleep: important findings to guide new approaches and reduce concerns. American journal of respiratory and critical care medicine, 2014, Dec-01, Volume: 190, Issue:11 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Female; Humans; Infant, Premature, Diseases; Male; Sleep; Sleep Wake Disorders	2014
Very long apnea events in preterm infants. Journal of applied physiology (Bethesda, Md. : 1985), 2015, Mar-01, Volume: 118, Issue:5 Topics: Apnea; Bradycardia; Caffeine; Continuous Positive Airway Pressure; Female; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Monitoring, Physiologic; Oxygen; Respiration	2015
Ampakines enhance weak endogenous respiratory drive and alleviate apnea in perinatal rats. American journal of respiratory and critical care medicine, 2015, Mar-15, Volume: 191, Issue:6 Topics: Analgesics, Opioid; Animals; Animals, Newborn; Apnea; Brain Stem; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Fetus; In Vitro Techniques; Plethysmography; Rats; Respiration; Respiratory Distress Syndrome, Newborn; Spinal Cord	2015
Caffeine in a term neonate with apnea. Indian pediatrics, 2015, Volume: 52, Issue:4 Topics: Apnea; Caffeine; Continuous Positive Airway Pressure; Humans; Infant, Newborn; Male; Ventilator Weaning	2015
The effect of caffeine citrate on neural breathing pattern in preterm infants. Early human development, 2015, Volume: 91, Issue:10 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Female; Humans; Infant, Newborn; Infant, Premature; Male; Respiration	2015
The Real-World Routine Use of Caffeine Citrate in Preterm Infants: A European Postauthorization Safety Study. Neonatology, 2016, Volume: 109, Issue:3 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Citrates; Europe; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Product Surveillance, Postmarketing	2016
Neonatal intensive care unit discharge of infants with cardiorespiratory events: Tri-country comparison of academic centers. Journal of neonatal-perinatal medicine, 2015, Volume: 8, Issue:4 Topics: Academic Medical Centers; Apnea; Caffeine; Canada; Central Nervous System Stimulants; Clinical Decision-Making; France; Gestational Age; Humans; Infant; Infant, Newborn; Intensive Care Units, Neonatal; Monitoring, Physiologic; Patient Discharge; Respiratory Function Tests; United States	2015
Clinical associations of immature breathing in preterm infants: part 1-central apnea. Pediatric research, 2016, Volume: 80, Issue:1 Topics: Algorithms; Apnea; Caffeine; Cohort Studies; Electrocardiography; Enterocolitis, Necrotizing; Female; Gestational Age; Hemorrhage; Humans; Infant; Infant, Newborn; Infant, Premature; Intensive Care, Neonatal; Male; Oxygen; Patient Discharge; Pregnancy; Respiration; Respiration Disorders; Retrospective Studies; Sepsis; Sleep Apnea, Central	2016
Mechanisms of modulation of cytokine release by human cord blood monocytes exposed to high concentrations of caffeine. Pediatric research, 2016, Volume: 80, Issue:1 Topics: Apgar Score; Apnea; Caffeine; Central Nervous System Stimulants; Comorbidity; Cyclic AMP; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Gene Expression Regulation; Humans; Infant, Newborn; Infant, Premature; Inflammation; Interleukin-10; Lipopolysaccharides; Male; Monocytes; Phosphoric Diester Hydrolases; Receptors, Purinergic P1; Transcription, Genetic; Tumor Necrosis Factor-alpha	2016
Incorporating pharmacodynamic considerations into caffeine therapeutic drug monitoring in preterm neonates. BMC pharmacology & toxicology, 2016, 06-07, Volume: 17, Issue:1 Topics: Apnea; Caffeine; Citrates; Drug Monitoring; Female; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Male; Retrospective Studies	2016
DBS-LC-MS/MS assay for caffeine: validation and neonatal application. Bioanalysis, 2016, Volume: 8, Issue:18 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Chromatography, Liquid; Dried Blood Spot Testing; Drug Monitoring; Hematocrit; Humans; Infant, Newborn; Infant, Premature; Limit of Detection; Tandem Mass Spectrometry	2016
[Current research status of drug therapy for apnea of prematurity]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2016, Volume: 18, Issue:9 Topics: Aminophylline; Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2016
Clinically significant cardiopulmonary events and the effect of definition standardization on apnea of prematurity management. Journal of perinatology : official journal of the California Perinatal Association, 2017, Volume: 37, Issue:1 Topics: Apnea; Birth Weight; Caffeine; Disease Management; Female; Gestational Age; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Length of Stay; Male; Monitoring, Physiologic; Respiration, Artificial; Retrospective Studies; United States	2017
Caffeine for apnea in bronchiolitis. The Journal of pediatrics, 2017, Volume: 182 Topics: Apnea; Bronchiolitis; Caffeine; Humans; Infant, Premature; Infant, Premature, Diseases	2017
Use of caffeine for preterm infants in Australia and New Zealand: A survey. Journal of paediatrics and child health, 2016, Volume: 52, Issue:12 Topics: Airway Extubation; Apnea; Caffeine; Health Care Surveys; Humans; Infant, Newborn; New Zealand; Practice Patterns, Physicians'; Premature Birth	2016
Economics of Home Monitoring for Apnea in Late Preterm Infants. Respiratory care, 2017, Volume: 62, Issue:1 Topics: Ambulatory Care; Apnea; Bradycardia; Caffeine; Central Nervous System Stimulants; Cost Savings; Gestational Age; Health Care Costs; Humans; Infant; Infant, Newborn; Infant, Premature; Length of Stay; Monitoring, Ambulatory; Oximetry; Oxygen; Patient Readmission	2017
Atrial arrhythmia after newborn eye exam, to caffeine or not to caffeine? Journal of neonatal-perinatal medicine, 2016, Volume: 9, Issue:4 Topics: Apnea; Atrial Premature Complexes; Bradycardia; Caffeine; Central Nervous System Stimulants; Cyclopentolate; Drug Interactions; Female; Fundus Oculi; Humans; Infant; Infant, Newborn; Infant, Premature; Mydriatics; Ophthalmoscopy; Phenylephrine; Retinopathy of Prematurity	2016
A low cost, simplified, and scaleable pneumotachograph and face mask for neonatal mouse respiratory measurements. Journal of pharmacological and toxicological methods, 2017, Volume: 86 Topics: Animals; Animals, Newborn; Apnea; Caffeine; Central Nervous System Stimulants; Equipment Design; Female; Humans; Infant; Male; Masks; Mice; Oxygen Consumption; Pregnancy; Respiratory Mechanics; Sudden Infant Death; Tidal Volume; Transducers, Pressure	2017
Respiratory responses to progesterone and allopregnanolone following chronic caffeine treatment in newborn female rats. Respiratory physiology & neurobiology, 2017, Volume: 240 Topics: Analysis of Variance; Anesthetics; Animals; Animals, Newborn; Apnea; Caffeine; Carbon Dioxide; Central Nervous System Stimulants; Drug Combinations; Female; Hypoxia; Male; Plethysmography; Pregnanolone; Progesterone; Progestins; Rats; Respiration; Sex Characteristics	2017
Neonatal Caffeine Treatment and Respiratory Function at 11 Years in Children under 1,251 g at Birth. American journal of respiratory and critical care medicine, 2017, 11-15, Volume: 196, Issue:10 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Child; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Male; Odds Ratio; Respiration, Artificial; Respiratory Function Tests	2017
Caffeine Citrate Dosing Adjustments to Assure Stable Caffeine Concentrations in Preterm Neonates. The Journal of pediatrics, 2017, Volume: 191 Topics: Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Citrates; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Weight Gain	2017
Pharmacotherapies for apnoea of prematurity: time to pause and consider targeted sex-specific strategies? Experimental physiology, 2018, 02-01, Volume: 103, Issue:2 Topics: Apnea; Caffeine; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male	2018
Comparative Efficacy and Safety of Caffeine and Aminophylline for Apnea of Prematurity: Few Concerns. Indian pediatrics, 2017, 12-15, Volume: 54, Issue:12 Topics: Aminophylline; Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2017
Comparative Efficacy and Safety of Caffeine and Aminophylline for Apnea of Prematurity: Few Concerns: Author's Reply. Indian pediatrics, 2017, 12-15, Volume: 54, Issue:12 Topics: Aminophylline; Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2017
[Comparative Study of the Efficacy and Safety of Caffeine and Aminophylline for the Treatment of Apnea in Preterm Infants]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2018, Volume: 138, Issue:2 Topics: Administration, Oral; Aminophylline; Apnea; Caffeine; Female; Humans; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Male; Safety; Treatment Outcome	2018
Effects of caffeine on the preterm brain: An observational study. Early human development, 2018, Volume: 120 Topics: Apnea; Brain; Caffeine; Electroencephalography; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Neuroprotective Agents; Oxygen; Spectroscopy, Near-Infrared	2018
Caffeine therapy for apnoea of prematurity: Wake up to the fact that sex matters. Experimental physiology, 2018, Volume: 103, Issue:10 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Retrospective Studies; Sex Characteristics	2018
Caffeine and supplemental oxygen effectively suppress periodic breathing with only minor effects during long episodes of apnoea in preterm infants. Acta paediatrica (Oslo, Norway : 1992), 2019, Volume: 108, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Female; Humans; Infant, Newborn; Infant, Premature; Male; Oxygen; Polysomnography; Prospective Studies	2019
The effect of caffeine loading on cerebral autoregulation in preterm infants. Acta paediatrica (Oslo, Norway : 1992), 2019, Volume: 108, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Cerebrovascular Circulation; Cohort Studies; Female; Homeostasis; Humans; Infant, Newborn; Infant, Premature; Male	2019
Caffeine use in preterm infants: from magic to uncertainty. Archivos argentinos de pediatria, 2018, 12-01, Volume: 116, Issue:6 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2018
High versus low dose caffeine in preterm infants. Acta paediatrica (Oslo, Norway : 1992), 2019, Volume: 108, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant; Infant, Newborn; Infant, Premature	2019
A pilot study of limb stimulation for the treatment of neonatal apnea. Medicine, 2018, Volume: 97, Issue:49 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Female; Foot; Hand; Humans; Infant, Newborn; Infant, Premature; Male; Massage; Pilot Projects; Retrospective Studies; Treatment Failure	2018
[Clinical effect of early or late administration of caffeine citrate in prevention and treatment of apnea in very low birth weight infants]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2018, Volume: 20, Issue:12 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Child; Citrates; Humans; Infant; Infant, Very Low Birth Weight; Retrospective Studies	2018
High versus low dose caffeine in preterm infants. Acta paediatrica (Oslo, Norway : 1992), 2019, Volume: 108, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant; Infant, Newborn; Infant, Premature	2019
Self-reported Quality of Life at Middle School Age in Survivors of Very Preterm Birth: Results From the Caffeine for Apnea of Prematurity Trial. JAMA pediatrics, 2019, 05-01, Volume: 173, Issue:5 Topics: Apnea; Caffeine; Case-Control Studies; Central Nervous System Stimulants; Child; Female; Follow-Up Studies; Health Status Indicators; Humans; Infant, Extremely Premature; Infant, Newborn; Infant, Premature, Diseases; Male; Quality of Life; Self Report; Survivors; Treatment Outcome	2019
Dosing and Safety of Off-label Use of Caffeine Citrate in Premature Infants. The Journal of pediatrics, 2019, Volume: 211 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Cerebral Hemorrhage; Citrates; Ductus Arteriosus, Patent; Electronic Health Records; Enterocolitis, Necrotizing; Female; Gestational Age; Humans; Infant, Extremely Premature; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Intensive Care, Neonatal; Male; Multivariate Analysis; Off-Label Use; Treatment Outcome	2019
Caffeine not associated with irritable behaviour in very low-birth-weight infants. Early human development, 2019, Volume: 137 Topics: Aminophylline; Apnea; Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Female; Humans; Infant Behavior; Infant, Newborn; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Irritable Mood; Male; Movement	2019
Is earlier better when it comes giving caffeine to preterm infants or are we risking unnecessary treatment and serious harm? Acta paediatrica (Oslo, Norway : 1992), 2020, Volume: 109, Issue:3 Topics: Apnea; Caffeine; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2020
Wide variation in caffeine discontinuation timing in premature infants. Journal of perinatology : official journal of the California Perinatal Association, 2020, Volume: 40, Issue:2 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Cohort Studies; Combined Modality Therapy; Drug Administration Schedule; Female; Hospitalization; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Male; Positive-Pressure Respiration; Respiration	2020
Caffeine treatment for bronchiolitis-related apnea in the pediatric intensive care unit. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2020, Volume: 27, Issue:1 Topics: Apnea; Bronchiolitis; Caffeine; Case-Control Studies; Central Nervous System Stimulants; Citrates; Female; Hospitalization; Humans; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Length of Stay; Male; Retrospective Studies	2020
Stopping caffeine in premature neonates: how long does it take for the level of caffeine to fall below the therapeutic range? The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:3 Topics: Apnea; Caffeine; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Retrospective Studies	2022
Developmental population pharmacokinetics of caffeine in Chinese premature infants with apnoea of prematurity: A post-marketing study to support paediatric labelling in China. British journal of clinical pharmacology, 2021, Volume: 87, Issue:3 Topics: Apnea; Caffeine; Child; China; Humans; Infant; Infant, Newborn; Infant, Premature; Marketing	2021
Population pharmacokinetic study of caffeine citrate in Chinese premature infants with apnea. Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:6 Topics: Apnea; Asian People; Caffeine; Central Nervous System Stimulants; Citrates; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Models, Biological; Nonlinear Dynamics; Retrospective Studies	2020
Childhood respiratory outcomes after neonatal caffeine therapy. Seminars in fetal & neonatal medicine, 2020, Volume: 25, Issue:6 Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Child; Citrates; Ductus Arteriosus, Patent; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Oxygen Inhalation Therapy	2020
When to start and stop caffeine and why respiratory status matters. Seminars in fetal & neonatal medicine, 2020, Volume: 25, Issue:6 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Humans; Hypoxia; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Respiration, Artificial	2020
Therapy for Apnoea of Prematurity: A Retrospective Study on Effects of Standard Dose and Genetic Variability on Clinical Response to Caffeine Citrate in Chinese Preterm Infants. Advances in therapy, 2021, Volume: 38, Issue:1 Topics: Apnea; Caffeine; China; Citrates; Humans; Infant; Infant, Newborn; Infant, Premature; Reference Standards; Retrospective Studies	2021
Is caffeine available and affordable in low and middle-income countries? A survey in sub-Saharan Africa. Seminars in fetal & neonatal medicine, 2020, Volume: 25, Issue:6 Topics: Africa South of the Sahara; Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Costs and Cost Analysis; Developing Countries; Health Services Accessibility; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Pharmaceutical Preparations; World Health Organization	2020
Pharmacokinetics, pharmacodynamics and metabolism of caffeine in newborns. Seminars in fetal & neonatal medicine, 2020, Volume: 25, Issue:6 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Dose-Response Relationship, Drug; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature, Diseases; Intensive Care Units, Neonatal	2020
The Pharmacokinetics of Caffeine in Preterm Newborns: No Influence of Doxapram but Important Maturation with Age. Neonatology, 2021, Volume: 118, Issue:1 Topics: Apnea; Caffeine; Doxapram; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2021
Are we over-treating hypoxic spells in preterm infants? Seminars in fetal & neonatal medicine, 2021, Volume: 26, Issue:3 Topics: Apnea; Caffeine; Humans; Hypoxia; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2021
Simultaneous quantitation of serum caffeine and its metabolites by ultra-high-performance liquid chromatography-tandem mass spectrometry for CYP1A2 activity prediction in premature infants. Biomedical chromatography : BMC, 2021, Volume: 35, Issue:9 Topics: Apnea; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Male; Tandem Mass Spectrometry	2021
Caffeine citrate for apnea of prematurity-One dose does not fit all a prospective study. Journal of perinatology : official journal of the California Perinatal Association, 2021, Volume: 41, Issue:9 Topics: Apnea; Caffeine; Citrates; Humans; Infant; Infant, Newborn; Infant, Premature; Prospective Studies	2021
Caffeine Duration for Apnea of Prematurity: All Bets Are Off! Indian journal of pediatrics, 2021, Volume: 88, Issue:12 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases	2021
Caffeine is a respiratory stimulant without effect on sleep in the short-term in late-preterm infants. Pediatric research, 2022, Volume: 92, Issue:3 Topics: Apnea; Caffeine; Carbon Dioxide; Central Nervous System Stimulants; Humans; Hypoxia; Infant; Infant, Newborn; Infant, Premature; Respiratory System Agents; Sleep	2022
Caffeine for the Treatment of Central Apnea in Trisomy 18: A Case Study in the Novel Use of Methylxanthines in Palliative Transport. Journal of palliative medicine, 2022, Volume: 25, Issue:5 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Sleep Apnea, Central; Trisomy 18 Syndrome; Xanthines	2022
Caffeine excites medial parabrachial nucleus neurons of mice by blocking adenosine A1 receptor. Brain research, 2022, 09-01, Volume: 1790 Topics: Adenosine; Animals; Apnea; Caffeine; Mice; Neurons; Parabrachial Nucleus; Receptor, Adenosine A1; Receptor, Adenosine A2A	2022
The Use of Caffeine for Apnoea Associated with Trisomy 13 and Trisomy 18. Irish medical journal, 2021, 09-20, Volume: 114, Issue:8 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Trisomy 13 Syndrome; Trisomy 18 Syndrome	2021
Therapeutic drug monitoring of caffeine and its primary metabolites in plasma using LC-ESI-MS/MS for apnea of prematurity treatment: Evaluation of ultrapure water as a surrogate matrix. Biomedical chromatography : BMC, 2022, Volume: 36, Issue:11 Topics: Animals; Apnea; Caffeine; Drug Monitoring; Humans; Infant, Newborn; Infant, Premature; Rats; Tandem Mass Spectrometry; Theobromine; Theophylline; Water	2022
Effectiveness and safety of early versus late caffeine therapy in managing apnoea of prematurity among preterm infants: a retrospective cohort study. International journal of clinical pharmacy, 2022, Volume: 44, Issue:5 Topics: Apnea; Caffeine; Cohort Studies; Humans; Infant; Infant, Newborn; Infant, Premature; Retrospective Studies	2022
Population pharmacokinetic modeling of caffeine in preterm infants with apnea of prematurity: New findings from concomitant erythromycin and AHR genetic polymorphisms. Pharmacological research, 2022, Volume: 184 Topics: Apnea; Caffeine; Erythromycin; Humans; Infant; Infant, Newborn; Infant, Premature; Polymorphism, Genetic; Receptors, Aryl Hydrocarbon	2022
The association of salivary caffeine levels with serum concentrations in premature infants with apnea of prematurity. European journal of pediatrics, 2022, Volume: 181, Issue:12 Topics: Apnea; Caffeine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infant, Premature, Diseases	2022
Evaluation of pharmaceutically compounded oral caffeine on the impact of medication adherence and risk of readmission among preterm neonates: A single-center quasi-experimental study. PloS one, 2022, Volume: 17, Issue:11 Topics: Apnea; Caffeine; Gestational Age; Humans; Infant; Infant, Newborn; Medication Adherence; Patient Readmission	2022
It is time for a rethink about caffeine therapy for apnoea of prematurity. Acta paediatrica (Oslo, Norway : 1992), 2023, Volume: 112, Issue:9 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infant, Premature, Diseases	2023
Comments on our paper about using caffeine for preterm infants helped to fill knowledge gaps. Acta paediatrica (Oslo, Norway : 1992), 2023, Volume: 112, Issue:9 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature	2023
Effects of caffeine on diaphragmatic activity in preterm infants. Pediatric pulmonology, 2023, Volume: 58, Issue:7 Topics: Apnea; Caffeine; Diaphragm; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Sleep Apnea Syndromes	2023
Caffeine for Apnea of Prematurity: Too Much or Too Little of a Good Thing. The Journal of pediatrics, 2023, Volume: 259 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infant, Premature, Diseases	2023
Serum caffeine concentrations in preterm infants: a retrospective study. Scientific reports, 2023, 06-26, Volume: 13, Issue:1 Topics: Apnea; Caffeine; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Retrospective Studies	2023
Effects of caffeine therapy for apnea of prematurity on sleep and neurodevelopment of preterm infants at 6 months of corrected age. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2023, Dec-01, Volume: 19, Issue:12 Topics: Apnea; Caffeine; Humans; Infant; Infant, Newborn; Infant, Premature; Polysomnography; Sleep	2023