caffeine and adenosine

caffeine has been researched along with adenosine in 597 studies

Research

Studies (597)

TimeframeStudies, this research(%)All Research%
pre-1990180 (30.15)18.7374
1990's155 (25.96)18.2507
2000's143 (23.95)29.6817
2010's93 (15.58)24.3611
2020's26 (4.36)2.80

Authors

AuthorsStudies
Browne, RG; Howard, HR; Koe, BK; Lebel, LA; Sarges, R; Seymour, PA1
Daly, JW1
Borea, PA; Dalpiaz, A; Gilli, G; Gilli, P; Scatturin, A; Varani, K1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bearne, SL; Lunn, FA; Roy, AC1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
de Lera Ruiz, M; Lim, YH; Zheng, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Berizzi, A; Bird, L; Culurgioni, S; Navratilova, IH; Olsen, RHJ; Rawlins, PB; Robinson, S; Shepherd, C; Thompson, LEJ; Varzandeh, S1
Kostopoulos, GK; Phillis, JW1
Wong, JL; Zady, MF1
Edstrom, JP; Kirkpatrick, JR; Kostopoulos, GK; Phillis, JW1
Mitsuda, H; Nakajima, K; Nishikawa, Y2
Borg, DC; Schmidt, J1
Hittelman, KJ; Rosak, C1
Bockaert, J; Perez, M; Premont, J1
Ozato, K1
Asano, T; Hidaka, H; Ochiai, Y1
Buckley, JT1
Finlayson, LH; Osborne, MP1
Ehara, T; Goto, M; Yatani, A1
Chiba, S; Furukawa, Y; Kobayashi, M1
Chiba, S1
Lohmann, W; Sapper, H; Schimmack, W1
Lohmann, W; Schimmack, W1
Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S1
David, M; Griesmacher, A; Horvath, G; Mueller, MM; Weigel, G1
Gadd, GM; Sabie, FT1
Mustafa, SJ; Ramagopal, MV1
Henry, JL; Yashpal, K1
Hara, T; Minematsu, N; Mizuki, Y; Obara, N; Ushijima, I; Yamada, M1
Holycross, BJ; Jackson, EK1
Dulloo, AG; Girardier, L; Seydoux, J2
Adén, U; Fredholm, BB; Johansson, B; Lindström, K; Svenningsson, P1
Brown, K; Newland, MC2
Domenici, MR; Frank, C; Sagratella, S; Scotti de Carolis, A; Zeng, YC1
Arizono, K; Brady, FO; Garrett, SH; Xiong, X1
Cooper, DR; Coulson, R; Johnson, RA; Olsson, RA; Scheinman, SJ1
Caporali, MG; Popoli, P; Scotti de Carolis, A2
Okamoto, K; Yamada, Y; Yoshida, H1
Huddart, H; Lynch, M1
Smits, P; Thien, T1
Nasir, T; Zarrindast, MR1
Mitsumoto, Y; Mohri, T; Ohkubo, T1
Guillet, R; Kellogg, CK1
Andén, NE; Casas, M; Ferré, S; Grabowska-Andén, M; Herrera-Marschitz, M; Ungerstedt, U1
Holtzman, SG; Mante, S; Minneman, KP1
Haraguchi, H; Kuribara, H1
Brownstone, RM; Geiger, JD; Lesiuk, HJ; Peeling, J; Rydzy, M; Saunders, JK; Sutherland, GR1
Arzubiaga, C; Biaggioni, I; Paul, S; Puckett, A1
Ammon, HP2
Holtzman, SG; Mumford, GK1
Beninger, RJ; Josselyn, SA1
Holtzman, SG2
Branch, RA; Brown, NJ; Porter, J; Ryder, D1
Branch, KR; Jackson, EK; Magee, WD; Oliver, RD; Tofovic, SP1
Seale, TW; Sekar, KC; Sheldon, RE; Toubas, PL1
Brechler, V; Garbarz, E; Lotersztajn, S; Pavoine, C; Pecker, F1
Elphick, M; Godfrey, PP; Powell, T; Taghavi, Z1
Crews, FT; Garg, LC; Narang, N1
Mante, S; Minneman, KP1
Lin, Y; Phillis, JW1
Haas, HL; Kostopoulos, G; Psarropoulou, C1
Hasegawa, T1
Lenders, JW; Smits, P; Thien, T1
Berman, RF; Lupica, CR; Rosen, JB; Whitcomb, K1
Contreras, E; Germany, A; Villar, M1
Ahn, D; Hirsh, JK; Hunt, JM; Silinsky, EM; Solsona, C1
Barrera, CM; Dohanich, GP; Dunlap, WP; Hunter, RE1
Centelles, JJ; Franco, R; Kinne, RK1
Barone, JJ; Grice, HC1
Biaggioni, I; Feoktistov, I; Hollister, AS; Paul, S; Robertson, D1
Boyet, S; Dumont, I; Nehlig, A; Pereira de Vasconcelos, A1
Lautt, WW1
Durcan, MJ; Morgan, PF1
Coffin, VL; Spealman, RD2
Barraco, RA; DeLong, RE; Phillis, JW; Washington, DO1
DeLander, GE; Hopkins, CJ1
Dar, MS; Wooles, WR1
Aitken, RJ; Irvine, S; Mattei, A1
Boekema, P; De Abreu, R; Smits, P; Thien, T; van 't Laar, A1
Mersmann, HJ1
Antunes-Rodrigues, J; Favaretto, AL; López-Jiménez, MA; Picanço-Diniz, DL; Valença, MM1
Greenblatt, DJ; Kaplan, GB; Leduc, BW; Shader, RI; Thompson, ML1
Baldwin, HA; File, SE1
Bedia, E; Donovan, JF; Hammitt, DG; Rogers, PR; Syrop, CH; Williamson, RA1
O'Regan, MH1
Adamson, P; Brammer, MJ; Campbell, IC; Hajimohammadreza, I; Mantzouridis, T; Xiang, JZ1
Diaz, C; Gill, JM; Schiffman, SS1
McPhee, MD; Whiting, SJ1
Appalsamy, M; Mosqueda-Garcia, R; Robertson, D; Tseng, CJ1
Schouten, J; Smits, P; Thien, T2
Biaggioni, I; Branch, RA; Jackson, EK; Paul, S; Robertson, D1
Cazzola, G; Dainotti, E; Maraschio, P; Piantanida, M; Tiepolo, L; Tupler, R1
Clark, M; Post, RM1
Holycross, BJ; Jackson, EK; Li, P1
Sosnowski, M; Stevens, CW; Yaksh, TL1
Lautt, WW; McQuaker, JE1
Phillis, JW3
Fujiwara, Y; Kazahaya, Y; Otsuki, S; Sandyk, R; Takeda, T1
Chisholm, RL; Drummond, IA1
Dunwiddie, TV1
DeLong, RE; Phillis, JW2
Lindblad, S; Rzepczynski, D; Zieve, L1
Bravo, M; López-Sáez, JF; Pincheira, J1
Holloway, WR; Thor, DH1
Fredholm, BB3
Ahlijanian, MK; Takemori, AE3
Durston, AJ; Weijer, CJ1
Goldberg, SR; Katz, JL; Prada, JA2
Green, RM; Stiles, GL1
Andersson, KE; Kjellin, G; Persson, CG1
Beeker, TG; Diaz, C; Schiffman, SS1
Fredholm, BB; Lindström, K2
Green, CL; Swanson, TH1
Daly, JW; Padgett, W; Shamim, MT; Ukena, D1
Corradetti, R; Pedata, F; Pepeu, G; Vannucchi, MG1
Biaggioni, IO; Branch, RA; Jackson, EK; Li, P; Ohnishi, A1
Phillis, JW; Stair, RE1
Spealman, RD1
Abla, KA; Carney, JM; Daly, JW; Seale, TW; Shamim, MT1
Giovannelli, L; Giovannini, MG; Pedata, F; Pepeu, G1
Jarvis, MF; Williams, M2
Dugich, MM; Hawkins, M; Porter, NM; Radulovacki, M; Urbancic, M1
Boyet, S; Collignon, A; Nehlig, A; Pereira de Vasconcelos, A1
Boulenger, JP; Marangos, PJ; Salem, N; Uhde, TW1
Smits, P; Thien, T; van 't Laar, A1
Jackson, EK; Kuan, CJ; Wells, JN1
Benedetti, M; Frank, C; Sagratella, S; Scotti de Carolis, A1
Benedetti, M; Popoli, P; Scotti de Carolis, A1
Finn, IB; Holtzman, SG1
Conlay, LA; Evoniuk, G; Wurtman, RJ1
Cheung, WT; Lee, CM; Ng, TB1
Greene, RW; Haas, HL1
Clark, RL; Cusick, WA; Eschbach, K; Heyse, JF1
Gutknecht, AM; Lozeman, FJ; Markovic, J; Stanley, JC1
Harvey, JA; Winsky, L1
Barraco, RA; Campbell, WR; Phillis, JW; Shehin, SE; Stair, RE1
Goldberg, SR; Katz, JL1
Daly, JW; Evoniuk, G; Jacobson, KA; Shamim, MT; Wurtman, RJ1
Henry, JL; Salter, MW1
Buckholtz, NS; Middaugh, LD1
Ferrario, P; Mantegazza, P; Zambotti, F; Zecca, L; Zonta, N1
Biaggioni, I; Feely, J; Goldberg, MR; Hollister, AS; Onrot, J; Robertson, D; Shaheen, O; Wilkinson, GR1
Carney, JM; Coffin, VL1
Evoniuk, G; von Borstel, RW; Wurtman, RJ1
Dews, PB; Glowa, JR; Malaspina, S; Sobel, E1
De Sarno, P; Giovannelli, L; Pedata, F; Pepeu, G1
González-Fernández, A; Hernández, P; López-Sáez, JF1
Holloway, FA; Shull, RN1
Marangos, PJ; Patel, J; Post, RM; Weiss, SR1
Greene, RW; Haas, HL; Hermann, A1
Chesielski, L; Kempf, E; Lehmann, A; Maitre, M; Mandel, P1
Molnár, J; Prágai, B1
Carmichael, WM1
Davies, JI; Peers, DG1
Bygdeman, S; Johnsen, O1
Haslam, RJ; Rosson, GM1
Butcher, RW; Hittelman, KJ1
Kacew, S; Singhal, RL1
Haslam, RJ1
Lin, PP1
Cazenave, JP; Guccione, MA; Mustard, JF; Packham, MA1
Lackie, JM1
Fujii, S; Okuda, H; Saito, Y1
Chapman, RA; Miller, DJ1
Dryden, EE; Manery, JF; Woo, YT1
Feldman, JF; Thayer, JP1
Doctor, RB; Jindal, MN; Kelkar, VV1
Frantsuzova, SB1
Brock, N; Pohl, VP1
Komatsu, Y1
Nitz, RE; Scholtholt, J; Schraven, E1
Chiba, S; Hashimoto, K; Kubota, K1
Kvamme, E; Reichelt, KL; Wedege, E1
Anderson, SM; Daly, JW; Padgett, W; Weir, RL1
Caldwell, P; Emmett-Oglesby, MW; Spencer, DG1
Daly, JW; Sugio, K1
Mantegazza, P; Tammiso, R; Zambotti, F; Zecca, L; Zonta, N1
Paul, SM; Skolnick, P1
Phillis, JW; Wu, PH2
Schimmel, RJ1
Hollins, C; Lloyd, H; Stone, TW1
Annau, Z; Katims, JJ; Snyder, SH1
Annau, Z; Bruns, RF; Daly, JW; Katims, JJ; Snyder, SH1
Plagemann, PG; Wohlhueter, RM1
Sklar, P; Snyder, SH1
Altman, HJ; Barraco, RA; Coffin, VL; Phillis, JW; Taylor, JA1
Persons, DL; Shankel, DM1
Coleman, RA1
Boulenger, JP; Marangos, PJ; Patel, J2
Migas, EA1
Iverson, LL1
Boulenger, JP; Marangos, PJ; Parma, AM; Patel, J; Post, RM1
Lal, H; Spencer, DG1
Deng, JF; Rall, TW; Spyker, DA; Steward, O1
Butts-Lamb, P; Daly, JW; Padgett, W1
Kulkarni, SK; Mehta, AK1
Gilboe, DP; Nuttall, FQ1
Barber, R; Butcher, RW; Goka, TJ1
Gould, RJ; Katims, JJ; Murphy, KM; Snyder, SH1
Pedata, F; Pepeu, G; Spignoli, G1
Carney, JM; Logan, L1
DeLong, RE; Phillis, JW; Preston, G1
Glowa, JR; Spealman, RD1
Pedata, F; Pepeu, GC; Spignoli, G1
Elliott, J; Jhamandas, K; Notman, H; Sutak, M1
Renshaw, AA; von Borstel, RW; Wurtman, RJ1
Levine, AS; Morley, JE; Oken, MM; Wager-Srdar, SA1
Collier, HO; Tucker, JF1
Dragunow, M; Goddard, GV1
Conlay, LA; von Borstel, RW; Wurtman, RJ1
Tolkovsky, AM1
Aller, P; de la Torre, C; González-Fernández, A1
González-Fernández, A; López-Sáez, JF; Mingo, R1
Green, RD; Miletich, RS; Radulovacki, M1
González-Fernández, A; López-Sáez, JF1
Chelack, BJ; Jiang, ZG; Phillis, JW1
McGarry, SJ; Williams, AJ1
Kamphuis, J; Smits, P; Thien, T1
Danhof, M; Gubbens-Stibbe, JM; Ijzerman, AP; Jacobson, KA; Mathôt, RA; Soudijn, W1
Cahill, CM; Sawynok, J; White, TD1
Charest, J; Li, J; Marchand, S1
Charland, SL; Melko, GP; Stanek, EJ1
Bayne, CJ; Chen, JH1
Daly, JW; Jacobson, KA; Nikodijević, O1
Schiffmann, SN; Vanderhaeghen, JJ1
Bravo, M; Gallo, C; Lopez-Saez, JF; Navarrete, MH; Pincheira, J1
Semenov, VV; Studentsova, IA1
Imaizumi, M; Miyazaki, S; Onodera, K1
Semenov, VV1
Behbehani, MM; Dollberg-Stolik, O1
Etzel, BA; Guillet, R1
De Abreu, RA; Rongen, GA; Smits, P; Thien, T; Van Belle, H; Ver Donck, K; Willemsen, JJ1
Cortijo, J; Morcillo, EJ; Orón, JD; Perpiñá, M1
Inoue, I; Maeda, K; Miwa, M; Morita, H; Nakai, S; Odani, H; Shinzato, T1
Jacobson, KA; Ji, XD; Kim, HO; Melman, N; Olah, ME; Stiles, GL1
Daly, JW; Nikodijevic, O; Shi, D; Wong, V1
Babey, AM; Palmour, RM; Young, SN1
Delle Donne, KT; Sonsalla, PK1
Bingmann, D; Moraidis, I1
Bennett, MR; Larkum, ME; Warren, DA1
Hunt, JM; Redman, RS; Silinsky, EM1
Shafaghi, B; Zarrindast, MR1
Howell, LL; Landrum, AM1
Cerqueira, MD; Jacobson, AF; Raisys, V; Shattuc, S1
Jarvis, MF; Martin, GE; Rossi, DJ1
Aranda, JV; Davis, GM; Lopes, JM; Mullahoo, K1
Hicks, JL; Salter, MW1
Bravo, M; Lopez-Saez, JF; Navarrete, MH; Pincheira, J; Rodriguez, M1
Fukuuchi, Y; Isozumi, K; Itoh, Y; Takeda, H1
Holtzman, SG; Woolfolk, DR1
Kuan, CJ; Tarng, JL; Tseng, CJ; Tung, CS1
Biaggioni, I; Kurunwune, B; Paul, S1
Krnjević, K; Zhu, PJ1
Daly, JW; Gallo-Rodriguez, C; Jacobson, KA; Maillard, M; Nikodijević, O; Padgett, WL1
Howell, LL1
Ahlberg, S; Brené, S; Fredholm, BB; Johansson, B; Lindefors, N; Persson, H; van der Ploeg, I1
Fink, JS; Pollack, AE1
Fisher, CE; Hughes, RN1
Poon, A; Sawynok, J1
Bauer, J; Berger, M; Biber, K; Fiebich, BL; Gyufko, K; van Calker, D1
Shaban, M; Smith, RA; Stone, TW1
Adeyemo, O; Buchanan, P; Jain, N; Kemp, N; Stone, TW1
Chern, Y; Ching, YH; Lai, HL; Lee, EH; Lee, YC; Wang, HL1
Barnes, RC; Carper, HT; Luong, LS; Mandell, GL; Sullivan, GW1
Hoock, C; Schmidt, H; Steinmetz, J1
Borbély, AA; Schwierin, B; Tobler, I1
Jen, SC; Rovainen, CM1
Fochtmann, L; Francis, A1
Kaneko, S; Mizuno, K; Okada, M1
Jackson, EK; Kusaka, H; Pfeifer, CA; Tofovic, SP1
Ferre, S; Fuxe, K; Popoli, P; Tinner-Staines, B1
Jacobson, KA; Lin, RC; Von Lubitz, DK1
Eigler, A; Endres, S; Greten, TF; Haslberger, C; Sinha, B; Sullivan, GW1
Kaneko, S; Kawata, Y; Kiryu, K; Mizuno, K; Okada, M; Tasaki, H; Wada, K1
Daly, JW; Evans, SM; Griffiths, RR; Holtzman, SG; Hughes, JR; Strain, EC1
Bernardi, G; Calabresi, P; Centonze, D; Pisani, A1
Hespel, P; Richter, EA; Vergauwen, L1
Fredholm, BB; Georgiev, V; Johansson, B; Lindström, K1
Snyder, SH1
Costentin, J; El Yacoubi, M; Heath, JK; Ledent, C; Parmentier, M; Pedrazzini, T; Schiffmann, SN; Vanderhaeghen, JJ; Vassart, G; Vaugeois, JM1
Chang, YH; Chern, Y; Ching, YH; Conti, M; Lai, HL; Lee, YC1
Conant, JA; Conlay, LA; deBros, F; Wurtman, R1
Huddart, H; King, JA; Staff, WG1
Frobenius, W; Geis, U; Hipp, J; Müller, CE; Pawłowski, M; Sandoval-Ramírez, J; Schobert, U; Suzuki, F1
Cunha, RA; Gonçalves, ML; Ribeiro, JA1
Chiang, PH; Lee, JN; Tsai, EM1
Drazba, JA; Krahl, SE; Liu, YZ; Rivkees, SA; Swanson, TH1
Akimoto, T; Mashimoto, S; Suetsugi, M; Ushijima, I; Watanabe, K; Yamada, M1
Job, RF; Minor, TR; Woodson, JC1
Eikvar, L; Kirkebøen, KA1
Ando, S; Brooks, SC; Floras, JS; Notarius, CF; Rongen, GA1
O'Regan, MH; Phillis, JW; Song, D1
Khandwala, H; Loomis, CW; Zhang, Z1
Bennett, MR; Brain, KL; Lin, YQ1
Newland, MC1
Assmann, H; Illes, P; Nörenberg, W; Richter, M; Wirkner, K1
Kaneko, S; Okada, M1
Kaneko, S; Kawata, Y; Kondo, T; Mizuno, K; Murakami, T; Okada, M; Wada, K1
Hurwitz, R; Lyons, K; Taketa, R1
Richardt, G; Schreieck, J1
Dorsa, DM; Ward, RP1
Esser, MJ; Reid, AR; Sawynok, J1
Kaplan, GB; Weisberg, SP1
Bultynck, G; Casteels, R; De Smedt, H; De Smet, P; Maes, K; Missiaen, L; Parys, JB; Sienaert, I; Zizi, M1
Dixon, DA; Fenix, LA; Kim, DM; Raffa, RB1
Angel, M; Biaggioni, I; Cavalcante, J; Christman, B; Costa, F; Haile, V; Sulur, P1
Adair, TH; Anand, V; Brady, AL; Gu, JW; Kelly, WC; Moore, MC1
Dassesse, D; Goldberg, I; Schiffmann, SN; Vanderhaeghen, JJ; Vanderwinden, JM1
Fallahi, M; Mirnajafi-Zadeh, J; Palizvan, MR; Pourgholami, MH; Rostampour, M1
Kopf, SR; Melani, A; Pedata, F; Pepeu, G1
Blazev, R; Lamb, GD1
Ichikawa, S; Kitamura, S; Kuwana, Y; Nakamura, J; Shiozaki, S; Yamada, K1
Baldo, BA; Koob, GF; Markou, A1
Asano, A; Fraser, LR; Fujiwara, T; Funahashi, H; Nagai, T; Niwa, K1
Chrousos, GP; Crane, ML; Elenkov, IJ; Kino, T; Link, AA; McGuire, JL; Wilder, RL; Worth, JA1
Liu, XJ; Reid, A; Sawynok, J1
Borgeat, P; Bourgoin, SG; Harbour, D; Naccache, PH; Thibault, N1
Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM1
Aguirre-Bañuelos, P; Castañeda-Hernández, G; Granados-Soto, V; López-Muñoz, FJ; Pérez-Urizar, J1
Chad, JE; Pivovarov, AS; Walker, RJ1
Gean, PW; Lu, KT; Wu, SP1
Capasso, A1
Materi, LM; Rasmusson, DD; Semba, K1
Li, SN; Wong, PT1
Clowes, P; Majd-Ardekani, J; Menash-Bonsu, V; Nunan, TO1
Dixon, AK; Freeman, TC; Lee, K; Preston, Z; Richardson, PJ; Widdowson, L1
Adén, U; Fredholm, BB; Herlenius, E; Tang, LQ1
Dassesse, D; Ledent, C; Meunier, JC; Parmentier, M; Schiffmann, SN1
Chilian, WM; Jones, DW; Merkus, D; Nishikawa, Y; Stepp, DW1
Fathollahi, Y; Khalili, M; Semnanian, S1
Davies, DG; Fowler, JC; Gervitz, LM; Lutherer, LO; Pirch, JH1
Beilstein, MA; Chen, JF; Cuellar, B; Fink, JS; Grandy, DK; Hackett, E; Impagnatiello, F; Low, MJ; Moratalla, R; Ongini, E; Rubinstein, M; Schwarzschild, MA1
Fredholm, BB; Irenius, E; Kull, B; Schulte, G1
Funahashi, H; Nagai, T1
Chung, ES; Dobson, JG; Fenton, RA; Lorbar, M; Meyer, TE; Norton, GR; Perlini, S; Woodiwiss, AJ1
Dunwiddie, TV; Masino, SA1
Belluscio, L; Corvol, JC; Fienberg, AA; Girault, JA; Hervé, D; Jaber, M; Le Moine, C; Ledent, C; Studler, JM1
Dziubina, A; Gołembiowska, K1
Ashihara, H; Crozier, A; Kato, A; Koshiishi, C; Yama, S1
Betsholtz, C; Dunwiddie, TV; Escorihuela, RM; Fernández-Teruel, A; Fredholm, BB; Giménez-Llort, L; Halldner, L; Hårdemark, A; Herlenius, E; Johansson, B; Masino, SA; Poelchen, W; Wiesenfeld-Hallin, Z; Xu, XJ1
Atchison, DJ; Floras, JS; Notarius, CF; Rongen, GA1
Hleihel, W; Huchet-Cadiou, C; Léoty, C; Talon, S1
Carcillo, JA; Jackson, EK; Tofovic, SP; Zacharia, L1
Emala, CW; Lee, HT1
Hamann, M; Richter, A1
Antle, MC; Mistlberger, RE; Steen, NM1
Persson, PB1
Grbović, L; Pesić, S; Prostran, M; Radenković, M1
Curtis, SM; Dulhunty, AF; Gallant, EM; Haarmann, C; Laver, D; Pace, S1
Costentin, J; El Yacoubi, M; Ledent, C; Ongini, E; Parmentier, M; Vaugeois, JM1
Adén, U; Herlenius, E; Lagercrantz, H; Tang, LQ1
Shearman, LP; Weaver, DR1
Green, TA; Schenk, S1
Ashihara, H; Crozier, A; Kato, M; Ye, CX; Zheng, XQ1
Nguyen, TT; White, PJ1
Flood, AJ; Headrick, JP; Willems, L1
Deutsch, M; Fixler, D; Shainberg, A; Tirosh, R; Zinman, T1
Aslantas, A; Dokmeci, I; Firat, Z; Karadag, HC; Tamer, M; Ulugol, A1
Bibb, JA; Fienberg, AA; Fisone, G; Fredholm, BB; Greengard, P; Kim, Y; Lindskog, M; Nairn, AC; Pozzi, L; Svenningsson, P1
Büyükokuroğlu, ME; Demirezer, LO; Güvenalp, Z1
Boix, F; Hilgenfeldt, U; Knardahl, S; Rosenborg, L1
Carrega, L; Devaux, C; Fund-Saunier, O; Guieu, R; Peragut, JC; Pham, T; Saadjian, A; Sauze, N1
Da Silva, AL; Dall'Igna, OP; de Oliveira, RV; Dietrich, MO; Hoffmann, A; Lara, DR; Souza, DO1
Brenner, M; Danielczyk, W; Deckert, J; Durany, N; Jellinger, K; Paulus, W; Ransmayr, G; Riederer, P; Tatschner, T; Zöchling, R1
Antoniou, K; Ferré, S; Fuxe, K; Goldberg, SR; Justinova, Z; Karcz-Kubicha, M; Müller, CE; Pezzola, A; Popoli, P; Quarta, D; Reggio, R; Solinas, M; Terasmaa, A1
Blay, J; Butler, JJ; Hoskin, DW; Mader, JS; Watson, CL; Zhang, H1
Berrino, L; Capuano, A; De Novellis, V; Filippelli, A; Mazzeo, F; Rossi, F; Stella, L; Vitelli, MR1
Floras, JS; Notarius, CF; Rongen, GA1
O'Regan, MH; Phillis, JW1
TETZNER, KH1
DAVOREN, PR; SUTHERLAND, EW1
RIZACK, MA1
DEGUBAREFF, T; SLEATOR, W1
Brodmann, M; Lischnig, U; Lueger, A; Pilger, E; Stark, G1
Abo-Salem, OM; Bilkei-Gorzo, A; Filipek, B; Hayallah, AM; Müller, CE; Zimmer, A1
Lorist, MM; Tops, M1
Morelli, M1
Fredholm, BB; Svenningsson, P1
Costentin, J; El Yacoubi, M; Vaugeois, JM1
Chen, JF1
Goulart, EC; Kaster, MP; Rodrigues, AL; Rosa, AO; Rosso, MM; Santos, AR1
Aqel, RA; Baldwin, SA; Iskandrian, AE; Trimm, JR; Zoghbi, GJ1
Bach-Rojecky, L1
Henry, S; Noorbakhsh, F; Power, C; Schnermann, J; Tsutsui, S; Warren, K; Winston, BW; Yong, VW1
Cass, CE; Lang, TT; Young, JD1
Bodineau, L; Frugière, A; Gaytan, S; Gros, F; Saadani-Makki, F1
Batista, LC; Prediger, RD; Takahashi, RN1
Goto, W; Hirao, M; Ikeda, T; Kobayashi, T; Oku, H; Sugiyama, T1
Borycz, J; Ciruela, F; Ferré, S; Franco, R; Goldberg, SR; Hockemeyer, J; Lluis, C; Patkar, K; Quarta, D; Solinas, M; Woods, AS1
Funahashi, H; Romar, R1
Burchert, W; Fricke, E; Horstkotte, D; Wielepp, JP1
Ferré, S; Goldberg, SR; Karcz-Kubicha, M; Müller, CE; Schindler, CW; Tella, SR; Thorndike, EB1
Alexander West, G; Britz, GW; Groysman, L; Jensen, EM; Kung, DK; Meno, JR; Ngai, AC; Nguyen, TS; Winn, HR1
Prediger, RD; Takahashi, RN1
Dall'Igna, OP; de Oliveira, RV; Lara, DR; Neto, PF; Santos Gomes, MW; Schuh, JF; Souza, DO; Tort, AB1
Kogi, K; Konno, T; Nagai, A; Nakahata, N; Uchibori, T2
de Leeuw, PW; Houben, AJ; Koster, D; Kroon, AA; Postma, CT; Smits, P; van Engelshoven, JM; Wierema, TK1
Hoexter, MQ; Mello, LE; Rosa, PS; Tufik, S1
Brailoiu, E; Cooper, RL; Dropic, AJ1
Bertolasi, V; Ferretti, V; Pretto, L; Tabrizi, MA1
Antoniou, K; Bekris, E; Ferré, S; Goldberg, SR; Hyphantis, T; Marselos, M; Müller, CE; Panlilio, L; Papadopoulou-Daifoti, Z; Papathanasiou, G1
Becker, J; Ghisolfi, ES; Lara, DR; Luersen, G; Martins, FF; Ramos, FL; Schuch, A; Strimitzer, IM1
Aguilar, E; Bové, J; Cortés, R; Marin, C; Mengod, G; Serrats, J1
Ely, MR; Motl, RW; O'connor, PJ; Puetz, T; Tubandt, L1
Abraham, EH; Cho, SY; Engles, JM; Hilton, J; Polster, J; Wahl, RL1
Aqel, R; Blackmon, L; Heo, J; Htay, T; Iskandrian, AE; Zoghbi, GJ1
Chan, ES; Chen, JF; Cronstein, BN; Delano, DL; Desai, A; Fernandez, P; Friedman, SL; Montesinos, MC; Pillinger, MH; Reiss, AB; Schwarzschild, MA; Yee, H1
Conde, SV; Gonzalez, C; Obeso, A; Rigual, R; Rocher, A; Vicario, I1
da Silva, AL; Dall'Igna, OP; Hoffmann, A; Lara, DR; Souza, DO1
Arendash, GW; Cracchiolo, JR; Jackson, EK; Rezai-Zadeh, K; Schleif, W; Shippy, D; Tan, J; Zacharia, LC1
Bayes-Genis, A; Casadó, V; Cinca, J; Ciruela, F; Franco, R; Hove-Madsen, L; Llach, A; Lluis, C; Prat-Vidal, C1
Aubel, B; Bourgoin, S; Farré, A; Hamon, M; Kayser, V1
Achermann, P; Adam, M; Dürr, R; Gottselig, JM; Khatami, R; Landolt, HP; Rétey, JV1
Akundi, RS; Back, SA; Craig, A; Luo, NL; Ren, J; Ribeiro, I; Rivkees, SA1
Bishnoi, M; Chopra, K; Kulkarni, SK1
Chen, HH; Pan, HZ1
Bibb, JA; Galdi, S; Greene, RW; Hendrick, J; Sahin, B; Snyder, GL1
Borycz, J; Cunha, RA; Ferré, S; Goldberg, SR; Köfalvi, A; Melani, A; Panlilio, L; Pedata, F; Pereira, MF; Rodrigues, RJ1
Bangalore, S; Messerli, FH; Parkar, S1
Bakker, SJ; Bosselaar, M; Heine, RJ; Riksen, NP; Rongen, GA; Smits, P; Tack, CJ1
Daré, E; Fredholm, BB; Johansson, B; Tiselius, C; Valen, G; Yang, JN1
Gu, R; Li, W; Shan, H; Wang, J; Wang, WH; Xu, Y; Yang, B; Zhang, Y1
Baraldi, PG; Benini, A; Borea, PA; Gessi, S; Leung, E; Maclennan, S; Merighi, S; Mirandola, P; Simioni, C; Varani, K1
Shapiro, RE1
Franke, B; Riksen, NP; Rongen, GA; Smits, P; van den Broek, P1
Bishnoi, M; Kulkarni, SK; Singh, K1
Furukawa, K; Ishii, N; Kataoka, K; Nagao, K; Tsuru, H1
Cohen-Williams, ME; Grzelak, ME; Higgins, GA; Hodgson, RA; Pond, AJ; Varty, GB1
Antoniou, K; Borycz, J; Ciruela, F; Ferre, S; Franco, R; Goldberg, SR; Justinova, Z; Lluis, C; Quarta, D; Quiroz, C; Solinas, M1
Benko, I; Brugós, L; Cseppento, A; Deák, G; Edes, I; Galajda, Z; Gesztelyi, R; Kovács, P; Roszer, T; Sipka, S; Szentmiklósi, AJ; Szilasi, M; Zsuga, J1
Desfrere, L; Gressens, P; Olivier, P; Schwendimann, L; Verney, C1
Ferré, S1
Ramkumar, V; Toth, LA; Xie, X1
Binfaré, RW; Budni, J; Lobato, KR; Rodrigues, AL; Rosa, AO; Santos, AR1
Badner, J; Childs, E; de Wit, H; Deckert, J; Hohoff, C; Xu, K1
Coskun, C; Mutlu, D; Savci, V; Suzer, O; Yalcin, M; Yilmaz, MS1
McGeoch, RJ; Oldroyd, KG1
Landolt, HP1
Bhaskara, S; Chandrasekharan, MB; Ganguly, R1
Edelman, GM; Jing, J; Jones, FS; Stevens, A; Stonehouse, AH1
Benedek, G; Horvath, G; Kekesi, G; Nagy, E; Tuboly, G1
Batuca, JR; Conde, SV; Gonzalez, C; Monteiro, EC; Obeso, A1
Kjaergaard, J; Lukashev, D; Ohta, A; Sitkovsky, MV1
Balkin, TJ; Grugle, NL; Killgore, DB; Killgore, WD; Muckle, AE1
Burbiel, CE; Knittel, J; Müller, CE; Töpfer, M; Verspohl, EJ1
Cullen, PK; Furst, S; Minor, TR; Rowe, M1
Anagnostopoulos, C; Donovan, J; Harbinson, M; Loong, CY; Reyes, E; Underwood, SR1
Andretic, R; Greenspan, RJ; Han, KA; Jones, FS; Kim, YC1
Franco, R1
Koh, HC; Lee, CB1
Baghdoyan, HA; Lydic, R; Van Dort, CJ1
Chaimovitz, C; Douvdevani, A; Kachko, L; Nakav, S; Rogachev, B; Vorobiov, M; Zlotnik, M1
Chestley, T; Duckworth, ML; Mizuno, T; Parkinson, FE; Xiong, W; Zamzow, CR1
Boerman, OC; Dekker, D; Meijer, P; Oyen, WJ; Rongen, GA; Scheffer, GJ; Smits, P; van den Broek, PH; Wouters, CW1
Hollander, E1
Capasso, A; Gallo, C1
Kern, MJ; Salcedo, J1
Belikoff, B; Hatfield, S; Lukashev, D; Ohta, A; Sitkovsky, M1
Rose'Meyer, RB1
Jalali, A; Kawa, K; Larsen, C; Trevitt, J1
Boison, D; Li, T; Shen, HY1
Buntine, P; Cabalag, MS; Knott, JC; Meyer, A; Smit, D; Taylor, DM1
Hoffman, AF; Kawamura, M; Laaris, N; Lupica, CR; Masino, SA1
Ribeiro, JA; Sebastião, AM1
Bryant, SM; Karydes, HC1
Groszmann, RJ; Mehal, WZ; Ripoll, C; Zipprich, A1
Cressey, D1
Venton, BJ; Xu, Y1
Beconi, MT; Breininger, E; Cetica, PD1
de Rooij, M; Meijer, P; Rongen, GA; Scheffer, GJ; Smits, P; van den Broek, PH; Wouters, CW1
Carta, AR; Kachroo, A; Morelli, M; Schwarzschild, MA1
Boison, D1
Porkka-Heiskanen, T1
Díaz-Muñoz, M; Salín-Pascual, R1
Bauer, A; Elmenhorst, D; Garibotto, V; Prescher, A1
Lautt, WW; Ming, Z1
Franke, B; Peters, WH; Pickkers, P; Ramakers, BP; Riksen, NP; Smits, P; van den Broek, P; van der Hoeven, JG1
Rivkees, SA; Wendler, CC2
Hayaishi, O; Huang, ZL; Urade, Y1
Hirasawa, H1
Antonucci, I; Bucciarelli, T; De Caterina, R; Prontera, T; Renda, G; Ruggieri, B; Stuppia, L; Tatasciore, A; Zimarino, M1
Baskar, R; Jaiswal, P; Soldati, T; Thewes, S1
Hage, FG; Iskandrian, AE2
Barnett, AG; Fraser, JF; Johnson, LP; Khafagi, FA; Lee, JC; McHenry, CM; Walters, DL; Warnholtz, CR; Wilson, MG1
Agarwal, A; Agarwal, M; Agarwal, MK; Chakrabarti, A; Glick, A; Gupta, K; Sharma, JP; Wald, DN; Yang, J; Zhang, Y1
Belzowzki, A; Bergren, D; Brugler, A; Hillman, BG; Hillman, KC; Hillman, SR; Kuss, B; Ngo, BT; Pisarri, T; Rendell, MS; Thompson, SL; Turner, SA1
Conde, SV; Gonzalez, C; Monteiro, EC; Obeso, A; Ribeiro, MJ; Rigual, R1
Chatterjee, D; Chiu, GS; Darmody, PT; Freund, GG; Johnson, RW; Meling, DD; Walsh, JP1
Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J1
Deboer, T; Ferrari, MD; Meijer, JH; Van den Maagdenberg, AM; van Diepen, HC1
Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J1
Górska, A; Gołembiowska, K; Kamińska, K; Noworyta-Sokołowska, K; Wardas, J1
Meeusen, R; Roelands, B; Spriet, LL1
Bruner, RC; Choi, DS; Nam, HW1
Dayanim, S; Grewal, S; Londhe, VA; Lopez, B; Maisonet, TM1
Arheden, H; Carlsson, M; Ekelund, U; Hedén, B; Jögi, J; Markenroth Bloch, K; Ståhlberg, F1
Dierckx, RA; Elsinga, PH; Ishiwata, K; Khanapur, S; Meerlo, P; Paul, S; Sijbesma, JW; van Waarde, A1
Landolt, HP; Urry, E1
Pohanka, M1
Marczinski, CA1
Bakuradze, T; Baum, M; Eirich, M; Eisenbrand, G; Erk, T; Habermeyer, M; Montoya, GA; Richling, E1
Edvinsson, L; Haanes, KA1
Bilos, A; Deinum, J; Donders, AR; Riksen, NP; Rongen, GA; van den Berg, TN1
Matsuda, T; Matsumoto, H; Mikuri, M; Nakatsuma, K; Shimada, T; Ushimaru, S; Yamazaki, T1
Huang, YG; Shen, L; Xu, L; Zhang, YG1
Hanff, TC; Minor, TR1
Chang, CJ; Chen, SA; Chen, YC; Chen, YH; Chen, YJ; Kao, YH; Lin, YK; Lu, YY; Tsai, WC; Yang, LY1
Hiromura, M; Honda, S; Inoue, K; Kosako, K; Kuroki, H; Shiratani, T; Soeda, S; Toda, A; Uchiyama, H1
Boehm, SL; Fritz, BM1
Braun, OÖ; Christersson, C; Grove, EL; Halvorsen, S; James, SK; Lindholm, D; Storey, RF; Varenhorst, C1
Kawada, T; Matsuda, T; Matsumoto, H; Mikuri, M; Shimada, T; Takahashi, H; Takahashi, N; Ushimaru, S; Yamazaki, T1
Costa, G; Morelli, M; Simola, N1
Bajaj, NS; Hage, FG; Saab, R2
Brito, R; Calaza, KC; Paes-de-Carvalho, R; Pereira-Figueiredo, D; Socodato, R1
Jouret, F; Marx, B; Scuvée, É; Scuvée-Moreau, J; Seutin, V1
Faingold, CL; Kommajosyula, SP; Randall, M1
Kuijpers, D; Oudkerk, M; Prakken, NH; van der Harst, P; van Dijkman, PR; Vliegenthart, R1
Leiner, T1
Chuang, HC; Chuang, LT; Ho, SC; Li, YT; Wu, JJ; Yang, TT1
Fredholm, BB; Wang, Y; Yang, J1
Aho, V; Ikonen, HMK; Panula, P; Porkka-Heiskanen, T; Puttonen, HAJ; Salminen, T; Vainikka, M; Wigren, HK1
Kaandorp, TAM; Kuijpers, D; Oudkerk, M; van der Harst, P; van Dijk, R; van Dijkman, PRM; Vliegenthart, R1
Ateş, N; Dede, F; Eraldemir, FC; Karadenizli, S; Özsoy, ÖD; Şahin, D1
Bai, X; He, J; Li, T; Qiao, H; Xu, J; Ye, X; Zhang, J; Zhang, W1
Aires, ID; Ambrósio, AF; Baqi, Y; Boia, R; Cunha, RA; Elvas, F; Madeira, MH; Müller, CE; Rodrigues-Neves, AC; Santiago, AR; Szabó, EC; Tomé, ÂR; Tralhão, P1
Kaandorp, TAM; Kuijpers, D; Oudkerk, M; van Assen, M; van der Harst, P; van Dijk, R; van Dijkman, PRM; Vliegenthart, R1
Abu-Zaid, E; Birkmeier, S; Greulich, S; Kaesemann, P; Mahrholdt, H; Sechtem, U; Seitz, A; Vecchio, F1
Crespo, M; León-Navarro, DA; Martín, M1
Álvarez-Bagnarol, Y; Ayala-Santiago, C; Canela, EI; Casadó, V; Clemens, S; Cruz-Reyes, N; Díaz-Ríos, M; Ferré, S; Molina-Castro, GC; Moreno, E; Rivera-Oliver, M1
Andersson, J; Braun, OÖ; Heller, S; Henriksson, P; James, S; Lauermann, J; Lindholm, D; Öhagen, P; Varenhorst, C1
Fathalla, AM; Moustafa, AA; Soliman, AM1
de Paula Soares-Rachetti, V; Dos Santos, MKF; Gavioli, EC; Lobão-Soares, B; Rosa, LS1
Cardoso, AM; Carvalho, FB; Duarte, MMF; Gutierres, JM; Morsch, VM; Oliveira, L; Pillat, MM; Schetinger, MRC; Spanevello, RM; Stefanello, N; Ulrich, H; Vieira, JM1
Anastasiadi, RM; Berti, F; Di Tommaso, D; Peressi, M; Pividori, M; Redivo, L; Resmini, M1
Byrne, C; Forman, JL; Hasbak, P; Hurry, PK; Kjaer, A; Schmedes, A; Wissenberg, M1
Gilbert, N1
Cai, Q; Cao, T; Li, B; Li, H; Ma, T; Tian, Y; Xu, Y1
Babar, AK; Bui, L; DeGolovine, A; Gould, KL; Johnson, NP; Kitkungvan, D; Kumar, S; Madjid, M; Nacimbene, A; Patel, MB; Roby, AE; Vejpongsa, P1
Byrne, C; Hasbak, P; Kjaer, A1
Abdalla, FH; Bernardes, VM; Braun, JBS; Casali, EA; Castilhos, LG; da Cruz, IBM; de Andrade, CM; de Oliveira, JS; Leal, DBR; Manzoni, AG; Passos, DF; Ruchel, JB1
Bekeredjian, R; Chatzitofi, M; Greulich, S; Kaesemann, P; Löbig, S; Mahrholdt, H; Sechtem, U; Seitz, A; Tauscher, G1
Chong, JW; Lee, JC; Luis, SA1
Huang, CL; Lin, A; Lin, CT; Shih, CT; Tsai, YC; Wu, CC1
Gom, RC; Phillips, TJ; Teskey, GC; Wolff, MD1
Calzavara, MB; Camerini, BA; de Mattos Hungria, F; Ramos, AC; Suiama, MA1
Dong, M; Hu, K; Mo, H; Tang, S; Xiong, M; Zeng, Z; Zhao, D; Zhu, J1
Adachi, LNS; Assumpção, JAF; Battastini, AMO; Caumo, W; Cioato, SG; de Oliveira, C; de Souza, A; Medeiros, LF; Rozisky, JR; Scarabelot, VL; Silva, RS; Torres, ILS1
Cai, Z; Huang, R; Li, Y; Ma, Y; Pan, L; Wu, H; Wu, X1
Chen, JF; Schwarzschild, MA1
Banks, MI; Grady, SM; Jaeckel, ER; Krause, BM; Murphy, CA; Sanders, RD; Sultan, ZW1
Brito, R; Calaza, KC; Cunha-Rodrigues, MC; Nascimento, AA; Pereira-Figueiredo, D1
Hosonuma, M; Inoue, K; Kondo, S; Masaki, R; Matsumoto, H; Ogura, K; Oishi, Y; Okada, N; Sakai, K; Sato, S; Sekimoto, T; Shinke, T; Sumida, A; Takahashi, H; Tanaka, H; Tsujita, H; Tsukamoto, S1
Berman, NK; Cronstein, BN; Honig, S; Pillinger, MH1
Ishibashi, K; Ishii, K; Ishiwata, K; Miura, Y; Toyohara, J; Wagatsuma, K1
Byrne, C; Hasbak, P; Hurry, PK; Kjær, A; Lassen, ML; Schmedes, AV; Sheykhzade, M; Wissenberg, M1
Deboer, T; Landolt, HP; Reichert, CF1
Cai, X; Chen, J; Gyabaah, AT; Huang, ZL; Li, Y; Li, Z; Ma, C; Shi, H; Tu, Y; Yu, C1
Songy, B1
Li, Z; Liu, J; Lopez, A; Qin, K; Zhang, P1
Farinha-Ferreira, M; Rei, N; Ribeiro, JA; Sebastião, AM; Valente, CA; Vaz, SH1
Chen, JF; Choi, DS; Cunha, RA1
Agostinho, P; Canas, PM; Carvalho, RA; Cunha, RA; Ferreira, SG; Gaspar, I; Lopes, CR; Lopes, JP; Oliveira, A; Rodrigues, MS; Santos, J; Silva, HB; Simões, AP; Szabó, E; Tomé, ÂR1
Vellapandian, C; Yerragopu, AK1
Hok, L; Vianello, R1
Florén Lind, S; Frick, A; Grönbladh, A; Meurling, E; Stam, F; Zelleroth, S1
Ding, Y; Huang, PJ; Li, AZ; Liu, J; Xie, Y1
Dieckmann, T; Evans, NM; Huang, PJ; Li, AZ; Liu, J; Lu, C1
Gaber, M; Ghareeb, D; Hamed, A; Hamed, M; Mohamed, TM; Nofal, MS1

Reviews

54 review(s) available for caffeine and adenosine

ArticleYear
Adenosine receptors: targets for future drugs.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines

1982
Adenosine A2A receptor as a drug discovery target.
    Journal of medicinal chemistry, 2014, May-08, Volume: 57, Issue:9

    Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction

2014
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Biochemical mechanism of caffeine tolerance.
    Archiv der Pharmazie, 1991, Volume: 324, Issue:5

    Topics: Adenosine; Animals; Caffeine; Drug Tolerance; Humans

1991
The physiological role of adenosine in the central nervous system.
    International review of neurobiology, 1985, Volume: 27

    Topics: Adenosine; Adenylyl Cyclases; Analgesia; Animals; Behavior, Animal; Benzodiazepines; Brain Chemistry; Caffeine; Central Nervous System; Cerebrovascular Circulation; Drug Interactions; Electrophysiology; Ethanol; Humans; Locomotion; Narcotics; Neural Conduction; Neural Inhibition; Neurotransmitter Agents; Receptors, Cell Surface; Receptors, Purinergic; Sleep; Synapses; Time Factors; Vasodilation

1985
Effects of enprofylline and theophylline may show the role of adenosine.
    Life sciences, 1986, Mar-24, Volume: 38, Issue:12

    Topics: Adenosine; Animals; Asthma; Brain; Bronchodilator Agents; Caffeine; Diuresis; Fatty Acids, Nonesterified; Gastric Acid; Heart; Humans; Kidney; Kinetics; Lung; Natriuresis; Phosphodiesterase Inhibitors; Receptors, Cell Surface; Receptors, Purinergic; Respiration; Seizures; SRS-A; Theophylline; Vasoconstriction; Vasodilation; Xanthines

1986
Nifedipine: more than a calcium channel blocker.
    General pharmacology, 1986, Volume: 17, Issue:3

    Topics: Adenosine; Animals; Benzodiazepines; Biological Transport; Caffeine; Coronary Disease; Humans; Nifedipine; Receptors, Cell Surface; Receptors, Purinergic

1986
Adenosine antagonists as potential therapeutic agents.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:2

    Topics: Adenosine; Animals; Caffeine; Central Nervous System; Humans; Receptors, Purinergic; Species Specificity; Xanthines

1988
Coffee and the human cardiovascular system.
    The Netherlands journal of medicine, 1987, Volume: 31, Issue:1-2

    Topics: Adenosine; Blood Pressure; Caffeine; Cardiovascular System; Cholesterol; Coffee; Heart Diseases; Humans; Lipoproteins; Risk Factors

1987
Cyclic nucleotides in higher plants?
    Advances in cyclic nucleotide research, 1974, Volume: 4, Issue:0

    Topics: Adenine; Adenosine; Adenylyl Cyclases; Caffeine; Cyclic AMP; Gibberellins; Phosphoric Diester Hydrolases; Plant Growth Regulators; Plants; Protein Kinases; Theophylline

1974
[New aspects of the mechanism of the central nervous system stimulating effect of caffeine].
    Deutsche medizinische Wochenschrift (1946), 1984, Sep-28, Volume: 109, Issue:39

    Topics: Adenosine; Aminobutyrates; Animals; Brain; Caffeine; Calcium; Cyclic AMP; Habituation, Psychophysiologic; Humans; Mice; Naloxone; Phosphodiesterase Inhibitors; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Opioid; Receptors, Purinergic; Xanthines

1984
The mechanism(s) of action of the benzodiazepines.
    Medicinal research reviews, 1981,Spring, Volume: 1, Issue:1

    Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Caffeine; Carbolines; Cats; Cattle; Diazepam; gamma-Aminobutyric Acid; Humans; Molecular Weight; Muscle Relaxation; Neurotransmitter Agents; Niacinamide; Purines; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures; Sleep Wake Disorders

1981
The role of adenosine and its nucleotides in central synaptic transmission.
    Progress in neurobiology, 1981, Volume: 16, Issue:3-4

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphatases; Animals; Axonal Transport; Behavior, Animal; Benzodiazepines; Brain; Caffeine; Morphine; Nucleotidases; Receptors, Cell Surface; Receptors, Purinergic; Synapses

1981
Adenosine receptor interactions and anxiolytics.
    Neuropharmacology, 1983, Volume: 22, Issue:12B

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anti-Anxiety Agents; Benzodiazepines; Caffeine; Diazepam; Humans; Motor Activity; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic

1983
Xanthine interference with dipyridamole-thallium-201 myocardial imaging.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:4

    Topics: Adenosine; Animals; Caffeine; Coronary Disease; Dipyridamole; Dogs; False Negative Reactions; Heart; Humans; Male; Pentoxifylline; Radionuclide Imaging; Thallium Radioisotopes; Xanthine; Xanthines

1995
Astra Award Lecture. Adenosine, adenosine receptors and the actions of caffeine.
    Pharmacology & toxicology, 1995, Volume: 76, Issue:2

    Topics: Adenosine; Animals; Awards and Prizes; Brain; Caffeine; Humans; Neurotransmitter Agents; Pharmacology; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Societies, Scientific

1995
[Receptor mediated effects of adenosine and caffeine].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1998, Mar-30, Volume: 118, Issue:9

    Topics: Adenosine; Caffeine; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury; Receptors, Purinergic P1

1998
Indirect modulation of dopamine D2 receptors as potential pharmacotherapy for schizophrenia: I. Adenosine agonists.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:4

    Topics: Adenosine; Animals; Caffeine; Clinical Trials as Topic; Drug Interactions; Humans; Mutation; Neurotransmitter Agents; Receptors, Dopamine D2; Receptors, Purinergic P1; Schizophrenia

1999
The role and regulation of adenosine in the central nervous system.
    Annual review of neuroscience, 2001, Volume: 24

    Topics: Adenosine; Animals; Arousal; Caffeine; Central Nervous System; Humans; Neurons; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Sleep

2001
Caffeine, fatigue, and cognition.
    Brain and cognition, 2003, Volume: 53, Issue:1

    Topics: Adenosine; Attention; Caffeine; Central Nervous System Stimulants; Cognition; Dopamine; Electroencephalography; Fatigue; Humans; Reaction Time

2003
Adenosine A2A antagonists: potential preventive and palliative treatment for Parkinson's disease.
    Experimental neurology, 2003, Volume: 184, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Caffeine; Central Nervous System Stimulants; Humans; Neuroprotective Agents; Palliative Care; Parkinson Disease; Parkinson Disease, Secondary; Rats

2003
Adenosine-dopamine interactions: development of a concept and some comments on therapeutic possibilities.
    Neurology, 2003, Dec-09, Volume: 61, Issue:11 Suppl 6

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Humans; Mice; Nerve Tissue Proteins; Parkinson Disease; Phosphoproteins; Phosphorylation; Pyrimidines; Receptor, Adenosine A2A; Receptors, Dopamine D2; Signal Transduction; Triazoles

2003
The adenosine A(2A) receptor as an attractive target for Parkinson's disease treatment.
    Drug news & perspectives, 2003, Volume: 16, Issue:9

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Brain; Caffeine; Dopamine; Humans; Levodopa; Neuroprotective Agents; Parkinson Disease; Receptor, Adenosine A2A; Treatment Failure

2003
Caffeine and headaches.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2007, Volume: 28 Suppl 2

    Topics: Adenosine; Brain; Caffeine; Drug Combinations; Drug Synergism; Headache Disorders; Headache Disorders, Secondary; Humans; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome

2007
Adenosine A1-A2A receptor heteromers: new targets for caffeine in the brain.
    Frontiers in bioscience : a journal and virtual library, 2008, Jan-01, Volume: 13

    Topics: Adenosine; Animals; Brain; Caffeine; Central Nervous System Stimulants; Corpus Striatum; Dimerization; Humans; Models, Biological; Motor Activity; Receptor, Adenosine A1; Receptor, Adenosine A2A

2008
An update on the mechanisms of the psychostimulant effects of caffeine.
    Journal of neurochemistry, 2008, Volume: 105, Issue:4

    Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Humans; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1

2008
Adenosine and dopamine receptor interactions in striatum and caffeine-induced behavioral activation.
    Comparative medicine, 2007, Volume: 57, Issue:6

    Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Corpus Striatum; Dopamine; Humans; Locomotion; Models, Biological; Parkinson Disease; Parkinsonian Disorders; Receptors, Dopamine; Receptors, Purinergic P1; Rodentia; Signal Transduction

2007
Pharmacological options for inducing maximal hyperaemia during studies of coronary physiology.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Feb-01, Volume: 71, Issue:2

    Topics: Adenosine; Adenosine Triphosphate; Animals; Caffeine; Coronary Stenosis; Dobutamine; Fractional Flow Reserve, Myocardial; Humans; Hyperemia; Infusions, Intravenous; Nitroprusside; Papaverine; Vasodilator Agents

2008
Sleep homeostasis: a role for adenosine in humans?
    Biochemical pharmacology, 2008, Jun-01, Volume: 75, Issue:11

    Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Homeostasis; Humans; Receptors, Purinergic P1; Sleep

2008
Hypoxia-adenosinergic immunosuppression: tumor protection by T regulatory cells and cancerous tissue hypoxia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Oct-01, Volume: 14, Issue:19

    Topics: Adenosine; Animals; Caffeine; CD8-Positive T-Lymphocytes; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunosuppressive Agents; Immunotherapy; Mice; Models, Biological; Neoplasms; Receptor, Adenosine A2A; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory

2008
[Coffee and cancer].
    Medicina clinica, 2008, Nov-08, Volume: 131, Issue:16

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Anticarcinogenic Agents; Caffeine; Cell Transformation, Neoplastic; Coffee; Female; Humans; Lymphocyte Activation; Male; Mice; Mice, Transgenic; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Receptors, Adenosine A2; Theobromine; Theophylline

2008
Effects of caffeine and theophylline on coronary hyperemia induced by adenosine or dipyridamole.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Oct-01, Volume: 74, Issue:4

    Topics: Adenosine; Animals; Caffeine; Coronary Circulation; Coronary Disease; Dipyridamole; Drug Administration Schedule; Drug Interactions; Echocardiography, Doppler; Humans; Hyperemia; Myocardial Perfusion Imaging; Positron-Emission Tomography; Practice Guidelines as Topic; Predictive Value of Tests; Theophylline; Time Factors; Vasodilator Agents

2009
The antihypoxia-adenosinergic pathogenesis as a result of collateral damage by overactive immune cells.
    Journal of leukocyte biology, 2009, Volume: 86, Issue:3

    Topics: Acute Lung Injury; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Disease Models, Animal; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Mice; Mice, Mutant Strains; Oxygen; Oxygen Consumption; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Respiratory Distress Syndrome; T-Lymphocytes, Regulatory

2009
Caffeine and adenosine.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20 Suppl 1

    Topics: Adenosine; Animals; Caffeine; Cognition; Humans; Learning; Mental Disorders; Models, Biological; Nervous System Diseases; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1

2010
Pathophysiological roles for purines: adenosine, caffeine and urate.
    Progress in brain research, 2010, Volume: 183

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Caffeine; Dopamine; Humans; Neuroprotective Agents; Parkinson Disease; Purines; Receptor, Adenosine A2A; Uric Acid

2010
Methylxanthines, seizures, and excitotoxicity.
    Handbook of experimental pharmacology, 2011, Issue:200

    Topics: Adenosine; Animals; Caffeine; Humans; Neurotoxins; Seizures; Theophylline; Xanthines

2011
Methylxanthines and sleep.
    Handbook of experimental pharmacology, 2011, Issue:200

    Topics: Adenosine; Animals; Caffeine; Humans; Receptor, Adenosine A1; Receptors, Adenosine A2; Sleep

2011
Purine molecules as hypnogenic factors role of adenosine, ATP, and caffeine.
    Central nervous system agents in medicinal chemistry, 2010, Dec-01, Volume: 10, Issue:4

    Topics: Adenosine; Adenosine Triphosphate; Animals; Caffeine; Central Nervous System Stimulants; Humans; Hypnotics and Sedatives; Neurotransmitter Agents; Purines; Sleep; Structure-Activity Relationship; Synaptic Transmission

2010
Adverse and protective influences of adenosine on the newborn and embryo: implications for preterm white matter injury and embryo protection.
    Pediatric research, 2011, Volume: 69, Issue:4

    Topics: Adenosine; Animals; Caffeine; Embryo, Mammalian; Female; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infant, Premature; Leukomalacia, Periventricular; Nerve Fibers, Myelinated; Neuroprotective Agents; Oligodendroglia; Pregnancy; Protein Isoforms; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Respiration

2011
The role of adenosine in the regulation of sleep.
    Current topics in medicinal chemistry, 2011, Volume: 11, Issue:8

    Topics: Adenosine; Adenosine Triphosphate; Animals; Caffeine; Extracellular Space; Gene Expression; Humans; Mice; Mice, Knockout; Neurons; Neurotransmitter Agents; Nucleoside Transport Proteins; Preoptic Area; Prostaglandin D2; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A1; Receptor, Adenosine A2A; Sleep; Sleep Disorders, Circadian Rhythm; Subarachnoid Space; Synaptic Transmission; Wakefulness

2011
Adenosine signaling in striatal circuits and alcohol use disorders.
    Molecules and cells, 2013, Volume: 36, Issue:3

    Topics: Adenosine; Alcohol Drinking; Alcohol-Related Disorders; Animals; Caffeine; Choice Behavior; Corpus Striatum; Dopamine Antagonists; Ethanol; Humans; Mice; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Dopamine; Receptors, Purinergic P1; Signal Transduction

2013
Adenosine, caffeine, and performance: from cognitive neuroscience of sleep to sleep pharmacogenetics.
    Current topics in behavioral neurosciences, 2015, Volume: 25

    Topics: Adenosine; Attention; Caffeine; Humans; Neurosciences; Pharmacogenetics; Psychomotor Performance; Sleep; Sleep Deprivation

2015
The effects of caffeine on the cholinergic system.
    Mini reviews in medicinal chemistry, 2014, Volume: 14, Issue:6

    Topics: Acetylcholine; Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Cholinergic Agents; Cholinesterases; Cytokines; Humans; Receptors, Cholinergic

2014
Regulatory effect of caffeine on the acute and the chronic pain and its possible mechanisms.
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2014, Volume: 36, Issue:6

    Topics: Adenosine; Caffeine; Central Nervous System Stimulants; Chronic Pain; Humans; Pain

2014
[Mechanisms of caffeine-induced diuresis].
    Medecine sciences : M/S, 2016, Volume: 32, Issue:5

    Topics: Adenosine; Animals; Caffeine; Diuresis; Diuretics; Humans; Kidney Tubules; Receptors, Purinergic P1; Signal Transduction; Sodium

2016
Low, but not high, dose caffeine is a readily available probe for adenosine actions.
    Molecular aspects of medicine, 2017, Volume: 55

    Topics: Adenosine; Caffeine; Dose-Response Relationship, Drug; Humans

2017
Long-term consequences of disrupting adenosine signaling during embryonic development.
    Molecular aspects of medicine, 2017, Volume: 55

    Topics: Adenosine; Animals; Caffeine; DNA Methylation; Embryonic Development; Epigenesis, Genetic; Humans; Mice; Receptors, Purinergic P1; Signal Transduction

2017
Adenosine role in brain functions: Pathophysiological influence on Parkinson's disease and other brain disorders.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:4

    Topics: Adenosine; Brain Diseases; Caffeine; Dopamine; Humans; Parkinson Disease

2018
Craving espresso: the dialetics in classifying caffeine as an abuse drug.
    Naunyn-Schmiedeberg's archives of pharmacology, 2018, Volume: 391, Issue:12

    Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Craving; Dopamine; Humans; Illicit Drugs

2018
The Therapeutic Potential of Purinergic Receptors in Alzheimer's Disease and Promising Therapeutic Modulators.
    Mini reviews in medicinal chemistry, 2021, Volume: 21, Issue:11

    Topics: Adenosine; Alzheimer Disease; Caffeine; Humans; Protein Isoforms; Purinergic Agonists; Purinergic Antagonists; Receptors, Purinergic; Signal Transduction

2021
Do caffeine and more selective adenosine A
    Parkinsonism & related disorders, 2020, Volume: 80 Suppl 1

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Disease Models, Animal; Humans; Neuroprotective Agents; Parkinson Disease; Receptor, Adenosine A2A

2020
Caffeine and Its Neuroprotective Role in Ischemic Events: A Mechanism Dependent on Adenosine Receptors.
    Cellular and molecular neurobiology, 2022, Volume: 42, Issue:6

    Topics: Adenosine; Brain; Caffeine; Central Nervous System; Glucose; Humans; Ischemia; Neuroprotective Agents; Oxygen; Receptors, Purinergic P1; Retina

2022
Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives.
    Journal of sleep research, 2022, Volume: 31, Issue:4

    Topics: Adenosine; Caffeine; Circadian Rhythm; Humans; Sleep; Sleep Deprivation; Wakefulness

2022
Striatopallidal adenosine A
    Neuropharmacology, 2023, 03-15, Volume: 226

    Topics: Adenosine; Caffeine; Cognition; Corpus Striatum; Dopamine; Glutamates; Goals; Humans; Receptor, Adenosine A2A

2023

Trials

24 trial(s) available for caffeine and adenosine

ArticleYear
Caffeine potentiates the renin response to diazoxide in man. Evidence for a regulatory role of endogenous adenosine.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

    Topics: Adenosine; Adult; Blood Pressure; Caffeine; Catecholamines; Diazoxide; Drug Synergism; Drug Tolerance; Female; Humans; Infusions, Intravenous; Male; Pulse; Purinergic Antagonists; Renin; Time Factors

1991
Evidence for an antagonism between caffeine and adenosine in the human cardiovascular system.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:2

    Topics: Adenosine; Adult; Aldosterone; Blood Pressure; Caffeine; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Male; Oxygen Consumption; Random Allocation

1987
Cardiovascular effects of two xanthines and the relation to adenosine antagonism.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:6

    Topics: Adenosine; Adult; Aldosterone; Blood Pressure; Caffeine; Double-Blind Method; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Male; Nausea; Norepinephrine; Random Allocation; Renin; Xanthines

1989
Plasma adenosine levels: measurement in humans and relationship to the anxiogenic effects of caffeine.
    Psychiatry research, 1987, Volume: 21, Issue:3

    Topics: Adenosine; Adult; Anxiety; Caffeine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Psychological Tests; Random Allocation

1987
Respiratory stimulant effects of adenosine in man after caffeine and enprofylline.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:6

    Topics: Adenosine; Adult; Bronchodilator Agents; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Respiration; Respiratory Function Tests; Stimulation, Chemical; Xanthines

1987
Effects of caffeine on analgesia from transcutaneous electrical nerve stimulation.
    The New England journal of medicine, 1995, Aug-03, Volume: 333, Issue:5

    Topics: Adenosine; Adult; Caffeine; Double-Blind Method; Female; Humans; Male; Pain; Pain Measurement; Transcutaneous Electric Nerve Stimulation

1995
Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:2

    Topics: Adenosine; Adult; Blood Pressure; Caffeine; Carrier Proteins; Cross-Over Studies; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Epinephrine; Heart Rate; Humans; Infusions, Intra-Arterial; Injections, Intravenous; Male; Membrane Proteins; Middle Aged; Norepinephrine; Nucleoside Transport Proteins; Piperazines; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Antagonists; Reference Values; Systole; Vasodilation

1995
Role of adenosine in dialysis-induced hypotension.
    Journal of the American Society of Nephrology : JASN, 1994, Volume: 4, Issue:12

    Topics: Adenosine; Aged; Caffeine; Female; Humans; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Models, Biological; Norepinephrine; Renal Dialysis; Sympathetic Nervous System; Vascular Resistance; Vasodilation; Xanthine; Xanthines

1994
Adenosine challenge and boost protocols: new tools for myocardial perfusion imaging.
    Clinical nuclear medicine, 1999, Volume: 24, Issue:2

    Topics: Adenosine; Caffeine; Cardiac Output; Coronary Disease; Dipyridamole; Exercise Test; Heart; Humans; Radionuclide Imaging

1999
Effect of adenosine receptor blockade with caffeine on sympathetic response to handgrip exercise in heart failure.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:3

    Topics: Adenosine; Blood Pressure; Caffeine; Exercise Test; Female; Hand Strength; Heart Failure; Heart Rate; Humans; Infusions, Intravenous; Ischemia; Isometric Contraction; Isotonic Contraction; Male; Middle Aged; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Reflex; Sympathetic Nervous System

2001
Effect of caffeine administered intravenously on intracoronary-administered adenosine-induced coronary hemodynamics in patients with coronary artery disease.
    The American journal of cardiology, 2004, Feb-01, Volume: 93, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adult; Caffeine; Coronary Artery Disease; Hemodynamics; Humans; Hyperemia; Infusions, Intravenous; Injections, Intra-Arterial; Male; Middle Aged; Pilot Projects; Vasodilator Agents

2004
Caffeine modulates P50 auditory sensory gating in healthy subjects.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:3

    Topics: Adenosine; Adult; Analysis of Variance; Caffeine; Central Nervous System Stimulants; Electroencephalography; Electrooculography; Evoked Potentials, Auditory; Feeding Behavior; Female; Humans; Male; Receptors, Purinergic P1

2006
Adenosinergic mechanisms contribute to individual differences in sleep deprivation-induced changes in neurobehavioral function and brain rhythmic activity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Oct-11, Volume: 26, Issue:41

    Topics: Adenosine; Adult; Brain; Caffeine; Cross-Over Studies; Electroencephalography; Humans; Individuality; Male; Polysomnography; Psychomotor Performance; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sleep Deprivation; Sleep Stages

2006
Acute elevation of plasma non-esterified fatty acids increases pulse wave velocity and induces peripheral vasodilation in humans in vivo.
    Clinical science (London, England : 1979), 2007, Volume: 113, Issue:1

    Topics: Adenosine; Autonomic Nervous System; Blood Flow Velocity; Blood Pressure; Caffeine; Compliance; Cross-Over Studies; Fat Emulsions, Intravenous; Fatty Acids, Unsaturated; Forearm; Humans; Insulin; Pulse; Receptors, Purinergic P1; Vasodilation; Vasodilator Agents

2007
Rosuvastatin increases extracellular adenosine formation in humans in vivo: a new perspective on cardiovascular protection.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:6

    Topics: Adenosine; Administration, Oral; Annexin A5; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fluorobenzenes; Forearm; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Intra-Arterial; Male; Nitroprusside; Pyrimidines; Radionuclide Imaging; Regional Blood Flow; Reperfusion Injury; Rosuvastatin Calcium; Sulfonamides; Time Factors; Up-Regulation; Vasodilation; Vasodilator Agents

2009
Upregulation of ecto-5'-nucleotidase by rosuvastatin increases the vasodilator response to ischemia.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:4

    Topics: 5'-Nucleotidase; Adenosine; Blood Flow Velocity; Brachial Artery; Caffeine; Central Nervous System Stimulants; Female; Fluorobenzenes; Forearm; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Intra-Arterial; Ischemia; Male; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Time Factors; Up-Regulation; Vasodilator Agents; Young Adult

2010
Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury.
    Critical care (London, England), 2011, Volume: 15, Issue:1

    Topics: Adenosine; AMP Deaminase; Caffeine; Double-Blind Method; Endotoxemia; Escherichia coli; Humans; Immunity, Innate; Inflammation; Kidney; Lipopolysaccharides; Male; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1

2011
Genetic determinants of blood pressure responses to caffeine drinking.
    The American journal of clinical nutrition, 2012, Volume: 95, Issue:1

    Topics: Adenosine; Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Caffeine; Coffee; Double-Blind Method; Epinephrine; Humans; Male; Plant Extracts; Polymorphism, Genetic; Receptor, Adenosine A2A; Receptors, Adrenergic, alpha-2; Young Adult

2012
Effect of caffeine on adenosine-induced reversible perfusion defects assessed by automated analysis.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2012, Volume: 19, Issue:3

    Topics: Adenosine; Blood Flow Velocity; Caffeine; Coronary Artery Disease; Coronary Circulation; Drug Interactions; Exercise Test; Female; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Myocardial Perfusion Imaging; Reproducibility of Results; Sensitivity and Specificity; Vasodilator Agents

2012
Submaximal adenosine-induced coronary hyperaemia with 12 h caffeine abstinence: implications for clinical adenosine perfusion imaging tests.
    Clinical physiology and functional imaging, 2015, Volume: 35, Issue:1

    Topics: Adenosine; Adult; Blood Flow Velocity; Caffeine; Coronary Circulation; Drug Administration Schedule; Drug Interactions; Female; Humans; Magnetic Resonance Angiography; Male; Myocardial Perfusion Imaging; Reproducibility of Results; Sensitivity and Specificity; Vasodilation; Vasodilator Agents

2015
The effect of eplerenone on adenosine formation in humans in vivo: a double-blinded randomised controlled study.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Adenosine; Caffeine; Dipyridamole; Double-Blind Method; Eplerenone; Forearm; Hemodynamics; Humans; Hyperemia; Male; Nitroprusside; Regional Blood Flow; Spironolactone; Treatment Outcome; Young Adult

2014
Design and rationale of TROCADERO: A TRial Of Caffeine to Alleviate DyspnEa Related to ticagrelOr.
    American heart journal, 2015, Volume: 170, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine; Caffeine; Dose-Response Relationship, Drug; Double-Blind Method; Dyspnea; Electrocardiography; Purinergic P1 Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Ticagrelor

2015
Caffeine and incidence of dyspnea in patients treated with ticagrelor.
    American heart journal, 2018, Volume: 200

    Topics: Adenosine; Aged; Caffeine; Drug Monitoring; Dyspnea; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Patient Reported Outcome Measures; Purinergic P2Y Receptor Antagonists; Ticagrelor

2018
Quantitative myocardial perfusion positron emission tomography and caffeine revisited with new insights on major adverse cardiovascular events and coronary flow capacity.
    European heart journal. Cardiovascular Imaging, 2019, Jul-01, Volume: 20, Issue:7

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Aged; Caffeine; Cardiovascular Diseases; Coronary Circulation; Dipyridamole; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Positron-Emission Tomography; Purines; Pyrazoles

2019

Other Studies

519 other study(ies) available for caffeine and adenosine

ArticleYear
4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Cats; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Corpus Striatum; Male; Molecular Structure; Motor Activity; Purinergic Antagonists; Quinoxalines; Rats; Receptors, Purinergic; Sleep; Structure-Activity Relationship; Triazoles

1990
Binding thermodynamics as a tool to investigate the mechanisms of drug-receptor interactions: thermodynamics of cytoplasmic steroid/nuclear receptors in comparison with membrane receptors.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Estradiol; Female; Humans; In Vitro Techniques; Male; Metribolone; Pregnenediones; Prostate; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid; Thermodynamics; Uterus

2005
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Surface Plasmon Resonance Screening to Identify Active and Selective Adenosine Receptor Binding Fragments.
    ACS medicinal chemistry letters, 2022, Jul-14, Volume: 13, Issue:7

    Topics:

2022
Adenosine as a putative transmitter in the cerebral cortex. Studies with potentiators and antagonists.
    Life sciences, 1975, Oct-10, Volume: 17, Issue:7

    Topics: Action Potentials; Adenine Nucleotides; Adenosine; Animals; Blood Pressure; Caffeine; Cerebral Cortex; Dose-Response Relationship, Drug; Hexobendine; Male; Neurotransmitter Agents; Papaverine; Rats; Receptors, Drug; Structure-Activity Relationship; Theophylline

1975
Kinetics and mechanism of carbon-8 methylation of purine bases and nucleosides by methyl radical.
    Journal of the American Chemical Society, 1977, Jul-20, Volume: 99, Issue:15

    Topics: Adenine; Adenosine; Caffeine; Guanine; Guanosine; Hot Temperature; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Kinetics; Methods; Methylation; Photochemistry; Purine Nucleosides

1977
Effects of adenosine and adenine nucleotides on synaptic transmission in the cerebral cortex.
    Canadian journal of physiology and pharmacology, 1979, Volume: 57, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Brain; Caffeine; Cerebral Cortex; Male; Neural Inhibition; Neurons; Rats; Synapses; Synaptic Transmission; Theophylline

1979
Relationship between accumulation of guanine ribonucleotidyl-(3'-5')-adenosine and formation of riboflavin.
    Journal of nutritional science and vitaminology, 1977, Volume: 23, Issue:5

    Topics: Adenosine; Ascomycota; Caffeine; Depression, Chemical; Dinucleoside Phosphates; Escherichia coli; Glucose; Guanine Nucleotides; Neurospora crassa; Riboflavin; Saccharomyces cerevisiae; Saccharomycetales; Stimulation, Chemical

1977
Free radicals from purine nucleosides after hydroxyl radical attack.
    Radiation research, 1976, Volume: 65, Issue:2

    Topics: Adenine; Adenosine; Caffeine; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Free Radicals; Guanosine; Hydroxylation; Imidazoles; Inosine; Purine Nucleosides; Radiation Effects

1976
Formation of guanine ribonucleotidyl-(3'-5')-adenosine in a flavinogenic strain of Eremothecium ashbyii.
    Journal of nutritional science and vitaminology, 1976, Volume: 22, Issue:2

    Topics: Adenosine; Ascomycota; Caffeine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Culture Media; Dinucleoside Phosphates; Guanine Nucleotides; Phosphoric Diester Hydrolases; Riboflavin; Ribonucleases; Saccharomycetales

1976
Characterization of lipolytic responses of isolated white adipocytes from hamsters.
    Biochimica et biophysica acta, 1977, Feb-28, Volume: 496, Issue:2

    Topics: Adenosine; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Caffeine; Catecholamines; Cricetinae; Dose-Response Relationship, Drug; Glycerol; Insulin; Lipid Mobilization; Male; Nicotinic Acids; Norepinephrine; Phentolamine; Propranolol; Prostaglandins E

1977
Adenosine-sensitive adenylate cyclase in rat striatal homogenates.
    FEBS letters, 1977, Mar-15, Volume: 75, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; Caffeine; Corpus Striatum; Cyclic AMP; Kinetics; Male; Rats; Structure-Activity Relationship; Theophylline; Xanthines

1977
Effects of ACTH, adenyl compounds, and methylxanthines on goldfish erythrophores in culture.
    General and comparative endocrinology, 1977, Volume: 31, Issue:3

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adrenocorticotropic Hormone; Animals; Bucladesine; Caffeine; Cells, Cultured; Chromatophores; Cyclic AMP; Cytoplasmic Granules; Dose-Response Relationship, Drug; Goldfish; Kinetics; Microscopy, Phase-Contrast; Pigments, Biological; Theophylline; Xanthines

1977
Selective inhibition of separated forms of human platelet cyclic nucleotide phosphodiesterase by platelet aggregation inhibitors.
    Molecular pharmacology, 1977, Volume: 13, Issue:3

    Topics: Adenosine; Blood Platelets; Caffeine; Chromatography, DEAE-Cellulose; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dipyridamole; Humans; In Vitro Techniques; Kinetics; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phthalazines; Platelet Aggregation; Theophylline

1977
Properties of human erythrocyte phosphatidylinositol kinase and inhibition by adenosine, ADP and related compounds.
    Biochimica et biophysica acta, 1977, Jun-23, Volume: 498, Issue:1

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Caffeine; Cyclic AMP; Enzyme Activation; Erythrocytes; Guanine Nucleotides; Humans; Kinetics; Mercaptoethanol; Phosphatidylinositols; Phosphotransferases; Polyethylene Glycols; Theophylline

1977
Effect of cyclic-AMP and other compounds on electrical activity of neurohaemal tissue in Carausius.
    Journal of insect physiology, 1977, Volume: 23, Issue:4

    Topics: Action Potentials; Adenosine; Animals; Bucladesine; Caffeine; Cyclic AMP; Histamine; Insecta; Nervous System; Norepinephrine; Theophylline

1977
Interaction between caffeine and adenosine on the membrane current and tension component in the bullfrog atrial muscle.
    The Japanese journal of physiology, 1979, Volume: 29, Issue:4

    Topics: Action Potentials; Adenosine; Animals; Anura; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Manganese; Myocardial Contraction; Rana catesbeiana

1979
Effects of cardioactive substances on the post-stimulation potentiation of contractility in the isolated dog atrium.
    Japanese heart journal, 1978, Volume: 19, Issue:2

    Topics: Adenosine; Animals; Caffeine; Chlorides; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Manganese; Myocardial Contraction; Ouabain; Pentobarbital; Propranolol; Tetrodotoxin; Verapamil

1978
Differences in chronotropic and inotropic responses of canine atrial muscle and SA node pacemaker activity to adenosine and ACh.
    Japanese heart journal, 1976, Volume: 17, Issue:1

    Topics: Acetylcholine; Adenosine; Animals; Atrial Function; Atropine; Caffeine; Depression, Chemical; Dogs; Heart Rate; Myocardial Contraction; Physostigmine; Sinoatrial Node

1976
Stacking interactions of nucleobases: NMR-investigations. II. Self-association of purine-and pyrimidine-derivatives.
    Biophysics of structure and mechanism, 1975, Dec-19, Volume: 1, Issue:4

    Topics: Adenine; Adenosine; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Deuterium; Hypoxanthines; Magnetic Resonance Spectroscopy; Polymers; Purines; Pyrimidines; Thermodynamics; Uracil; Uric Acid; Water

1975
Association of sexual hormones with nucleobases in water: NMR-investigations.
    Biophysics of structure and mechanism, 1975, Dec-19, Volume: 1, Issue:4

    Topics: Adenine; Adenosine; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Deuterium; Estradiol; Hypoxanthines; Magnetic Resonance Spectroscopy; Purines; Pyrimidines; Testosterone; Thermodynamics; Uracil; Uric Acid; Water

1975
Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Caffeine; Electroencephalography; Male; Parasympatholytics; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Theophylline; Xanthines

1992
Functional implications of cAMP and Ca2+ on prostaglandin I2 and thromboxane A2 synthesis by human endothelial cells.
    Arteriosclerosis and thrombosis : a journal of vascular biology, 1992, Volume: 12, Issue:4

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Caffeine; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Epoprostenol; Humans; Kinetics; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2

1992
Effect of nucleosides and nucleotides and the relationship between cellular adenosine 3':5'-cyclic monophosphate (cyclic AMP) and germ tube formation in Candida albicans.
    Mycopathologia, 1992, Volume: 119, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine Nucleotides; Adenosine; Caffeine; Candida albicans; Cyclic AMP; Theophylline

1992
Analysis of the effects of adenosine in skinned bovine coronary artery.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:2

    Topics: Adenosine; Animals; Caffeine; Calcium; Cattle; Coronary Vessels; Dinoprost; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Octoxynol; Polyethylene Glycols; Potassium; Saponins

1992
Adenosine receptor link in an adrenal opioid-induced antinociception in the rat tail-flick test.
    Neuroscience letters, 1992, Apr-27, Volume: 138, Issue:2

    Topics: Adenosine; Analysis of Variance; Animals; Caffeine; Male; Nociceptors; Pain Measurement; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Purinergic; Substance P

1992
Effects of lithium and purinergic compounds on the behavioral and physiological aspects of restraint stress in rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3

    Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Defecation; Injections, Intraperitoneal; Injections, Intraventricular; Lithium; Male; Motor Activity; Purines; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer; Stress, Psychological

1992
Effects of chronic treatment with caffeine on kidney responses to angiotensin II.
    European journal of pharmacology, 1992, Sep-04, Volume: 219, Issue:3

    Topics: Adenosine; Angiotensin II; Animals; Caffeine; Drug Administration Schedule; Glomerular Filtration Rate; Kidney; Kidney Function Tests; Male; Perfusion; Rats; Rats, Sprague-Dawley

1992
Potentiation of the thermogenic antiobesity effects of ephedrine by dietary methylxanthines: adenosine antagonism or phosphodiesterase inhibition?
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:11

    Topics: Adenosine; Adipose Tissue, Brown; Animals; Caffeine; Diet; Dose-Response Relationship, Drug; Drug Synergism; Eating; Ephedrine; Fasting; Hot Temperature; Male; Obesity; Oxygen Consumption; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Theobromine; Xanthines

1992
Evidence that the increase in striatal c-fos following acute high-dose caffeine is not due to direct interaction with striatal adenosine receptors.
    Acta physiologica Scandinavica, 1992, Volume: 146, Issue:4

    Topics: Adenosine; Animals; Caffeine; Corpus Striatum; Dose-Response Relationship, Drug; Genes, fos; Purinergic Antagonists; Quinazolines; Rats; RNA, Messenger; Triazoles; Xanthines

1992
Oral caffeine consumption by rats: the role of flavor history, concentration, concurrent food, and an adenosine agonist.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: Adenosine; Animals; Caffeine; Drinking Behavior; Feeding Behavior; Food; Male; Phenylisopropyladenosine; Quinine; Rats; Taste

1992
Effects of adenosinergic drugs on hypoxia-induced electrophysiological changes in rat hippocampal slices.
    Life sciences, 1992, Volume: 51, Issue:13

    Topics: Adenosine; Animals; Caffeine; Dizocilpine Maleate; Electrophysiology; Hippocampus; Hypoxia; In Vitro Techniques; Male; Membrane Potentials; Phenethylamines; Phenylisopropyladenosine; Potassium; Purinergic Antagonists; Rats; Rats, Inbred Strains; Synapses; Xanthines

1992
Purinergic agonist induction of metallothionein.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 201, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Cells, Cultured; Cladribine; Deoxyadenosines; Dose-Response Relationship, Drug; Immunoblotting; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; RNA, Messenger; Theophylline; Time Factors; Transcription, Genetic; Vasodilator Agents

1992
Adenosine stimulates phosphate and glucose transport in opossum kidney epithelial cells.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 2

    Topics: Adenosine; Aminoisobutyric Acids; Animals; Biological Transport; Caffeine; Carrier Proteins; Cells, Cultured; Cyclic AMP; Dideoxyadenosine; Epithelium; Glucose; Kidney; Opossums; Phenylisopropyladenosine; Phosphates; Protein Kinase C; Sodium-Phosphate Cotransporter Proteins; Symporters

1991
Akinesia due to catecholamine depletion in mice is prevented by caffeine. Further evidence for an involvement of adenosinergic system in the control of motility.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:4

    Topics: Adenosine; alpha-Methyltyrosine; Animals; Caffeine; Catecholamines; Dose-Response Relationship, Drug; Male; Methyltyrosines; Mice; Motor Activity; Movement Disorders; Reserpine; Tyrosine 3-Monooxygenase

1991
DC6, a novel type of Dictyostelium discoideum gene regulated by secreted factors but not by cAMP.
    Differentiation; research in biological diversity, 1991, Volume: 46, Issue:3

    Topics: Adenosine; Animals; Blotting, Northern; Caffeine; Cell Differentiation; Cell Fractionation; Cloning, Molecular; Cyclic AMP; Dictyostelium; Gene Expression Regulation, Fungal; Genes, Fungal; RNA

1991
Purinergic modulation of field stimulation responses of rat and human vas deferens smooth muscle.
    General pharmacology, 1991, Volume: 22, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Electric Stimulation; Guanethidine; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Quinidine; Rats; Receptors, Purinergic; Theophylline; Urinary Bladder; Vas Deferens; Vasodilator Agents

1991
Effects of adenosine on human coronary arterial circulation.
    Circulation, 1991, Volume: 84, Issue:5

    Topics: Adenosine; Caffeine; Coronary Circulation; Dose-Response Relationship, Drug; Humans

1991
Methylxanthine-induced attenuation of pecking in chickens.
    British journal of pharmacology, 1991, Volume: 104, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apomorphine; Behavior, Animal; Caffeine; Chickens; Dipyridamole; Female; Male; Theophylline; Xanthines

1991
Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives.
    Neuroscience letters, 1991, Dec-09, Volume: 133, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Affinity Labels; Animals; Biological Transport; Caffeine; Cells, Cultured; Cytarabine; Dipyridamole; Embryo, Mammalian; Hippocampus; Kinetics; Neuroglia; Neurons; Pentoxifylline; Rats; Sodium; Theophylline; Thioinosine; Tritium; Xanthines

1991
Neonatal caffeine exposure alters developmental sensitivity to adenosine receptor ligands.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:4

    Topics: Adenosine; Age Factors; Animals; Animals, Newborn; Brain; Caffeine; Kinetics; Ligands; Motor Activity; Phenylisopropyladenosine; Rats; Receptors, Purinergic

1991
Postsynaptic dopamine/adenosine interaction: II. Postsynaptic dopamine agonism and adenosine antagonism of methylxanthines in short-term reserpinized mice.
    European journal of pharmacology, 1991, Jan-03, Volume: 192, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bromocriptine; Caffeine; Dopamine; Male; Mice; Motor Activity; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine; Sulpiride; Synapses; Theophylline; Xanthines

1991
Role of adenosine receptors in caffeine tolerance.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Administration, Oral; Animals; Binding Sites; Brain; Caffeine; Cyclic AMP; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Time Factors; Tritium; Xanthines

1991
Behavioral effects of adenosine agonists: evaluation by punishment, discrete shuttle avoidance and activity tests in mice.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:3

    Topics: Adenosine; Animals; Avoidance Learning; Caffeine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred Strains; Motor Activity; Phenylisopropyladenosine; Punishment; Reinforcement Schedule; Xanthines

1991
The effects of caffeine on ischemic neuronal injury as determined by magnetic resonance imaging and histopathology.
    Neuroscience, 1991, Volume: 42, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Brain Ischemia; Caffeine; Cerebral Cortex; Corpus Striatum; Hippocampus; Histocytochemistry; Magnetic Resonance Imaging; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Purinergic

1991
Caffeine and theophylline as adenosine receptor antagonists in humans.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Caffeine; Heart Rate; Humans; Male; Platelet Aggregation; Purinergic Antagonists; Receptors, Purinergic; Substance Withdrawal Syndrome; Theophylline

1991
Peripheral mechanisms of thermogenesis induced by ephedrine and caffeine in brown adipose tissue.
    International journal of obesity, 1991, Volume: 15, Issue:5

    Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature Regulation; Caffeine; Culture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Ephedrine; Male; Oxygen Consumption; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Theophylline; Xanthines

1991
Qualitative differences in the discriminative stimulus effects of low and high doses of caffeine in the rat.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3

    Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Administration Schedule; Locomotion; Male; Motor Activity; Rats; Rats, Inbred Strains; Xanthines

1991
Behavioral effects of intrastriatal caffeine mediated by adenosinergic modulation of dopamine.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Animals; Behavior, Animal; Caffeine; Corpus Striatum; Dopamine; Flupenthixol; Male; Microinjections; Rats; Rats, Inbred Strains; Rotation; Stereoisomerism; Stereotyped Behavior

1991
CGS 15943, a nonxanthine adenosine receptor antagonist: effects on locomotor activity of nontolerant and caffeine-tolerant rats.
    Life sciences, 1991, Volume: 49, Issue:21

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Motor Activity; Quinazolines; Rats; Rats, Inbred Strains; Triazoles

1991
Caffeine potentiates vasodilator-induced renin release.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3

    Topics: Adenosine; Analysis of Variance; Animals; Blood Pressure; Caffeine; Chromatography, High Pressure Liquid; Drug Synergism; Hydralazine; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Renin; Xanthines

1991
Fetal and newborn lambs differ in their cardiopulmonary responsiveness to adenosine agonists.
    Developmental pharmacology and therapeutics, 1990, Volume: 15, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Blood Pressure; Bradycardia; Caffeine; Female; Heart; Heart Rate, Fetal; Hydrogen-Ion Concentration; Phenylisopropyladenosine; Pregnancy; Pulmonary Gas Exchange; Respiration; Sheep; Vasodilator Agents

1990
Activation of Na+/Ca2+ exchange by adenosine in ewe heart sarcolemma is mediated by a pertussis toxin-sensitive G protein.
    The Journal of biological chemistry, 1990, Oct-05, Volume: 265, Issue:28

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Calcium; Female; GTP-Binding Proteins; Guanosine; Heart Ventricles; Inosine; Kinetics; Myocardium; Pertussis Toxin; Phenylisopropyladenosine; Sarcolemma; Sheep; Sodium; Virulence Factors, Bordetella

1990
Chronic carbamazepine down-regulates adenosine A2 receptors: studies with the putative selective adenosine antagonists PD115,199 and PD116,948.
    Psychopharmacology, 1990, Volume: 100, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Brain Chemistry; Caffeine; Carbamazepine; Clonidine; Cyclic AMP; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenylisopropyladenosine; Purines; Receptors, Adrenergic; Sulfonamides; Theophylline; Xanthines

1990
Adenosine and its analogs stimulate phosphoinositide hydrolysis in the kidney.
    Pharmacology, 1990, Volume: 40, Issue:2

    Topics: Adenosine; Animals; Caffeine; Dose-Response Relationship, Drug; Hydrolysis; In Vitro Techniques; Kidney; Kidney Medulla; Male; Phosphatidylinositols; Rabbits; Receptors, Muscarinic

1990
Is adenosine involved in inhibition of forskolin-stimulated cyclic AMP accumulation by caffeine in rat brain?
    Molecular pharmacology, 1990, Volume: 38, Issue:5

    Topics: Adenosine; Adenosine Deaminase; Animals; Brain Chemistry; Caffeine; Cerebral Cortex; Colforsin; Cyclic AMP; Dipyridamole; Drug Synergism; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Purinergic

1990
Chronic caffeine exposure enhances adenosinergic inhibition of cerebral cortical neurons.
    Brain research, 1990, Jun-18, Volume: 520, Issue:1-2

    Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Dose-Response Relationship, Drug; Electrophysiology; Male; Neurons; Rats; Rats, Inbred Strains; Reference Values

1990
An electrophysiological study of the ontogenesis of adenosine receptors in the CA1 area of rat hippocampus.
    Brain research. Developmental brain research, 1990, Aug-01, Volume: 55, Issue:1

    Topics: Action Potentials; Adenosine; Animals; Caffeine; Female; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Thioinosine

1990
Depressive effects of lipid peroxides mediated via a purine receptor. Effect of lipid peroxide on the cortical synaptosomal GTPase activity.
    Biochemical pharmacology, 1990, Oct-01, Volume: 40, Issue:7

    Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Circadian Rhythm; Down-Regulation; GTP Phosphohydrolases; Lipid Peroxides; Locomotion; Mice; Phenobarbital; Rats; Receptors, Purinergic; Synaptosomes

1990
Caffeine and theophylline attenuate adenosine-induced vasodilation in humans.
    Clinical pharmacology and therapeutics, 1990, Volume: 48, Issue:4

    Topics: Adenosine; Adolescent; Adult; Bronchodilator Agents; Caffeine; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Regional Blood Flow; Theophylline; Vasodilation; Xanthines

1990
Adenosine involvement in postictal events in amygdala-kindled rats.
    Epilepsy research, 1990, Volume: 6, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amygdala; Animals; Anticonvulsants; Caffeine; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Kindling, Neurologic; Male; Rats; Seizures; Theophylline; Time Factors

1990
Effects of some adenosine analogs on morphine-induced analgesia and tolerance.
    General pharmacology, 1990, Volume: 21, Issue:5

    Topics: 2-Chloroadenosine; Adenosine; Analgesics; Animals; Caffeine; Drug Synergism; Drug Tolerance; Injections, Intraventricular; Mice; Morphine; Naloxone; Phenylisopropyladenosine

1990
The effects of TMB-8 on acetylcholine release from frog motor nerve: interactions with adenosine.
    European journal of pharmacology, 1990, Mar-27, Volume: 178, Issue:3

    Topics: Acetylcholine; Adenosine; Animals; Caffeine; Calcium Channel Blockers; Gallic Acid; In Vitro Techniques; Motor Endplate; Motor Neurons; Rana pipiens

1990
Effects of uric acid and caffeine on A1 adenosine receptor binding in developing rat brain.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:4

    Topics: Adenosine; Aging; Animals; Binding, Competitive; Brain; Caffeine; Male; Oxonic Acid; Rats; Rats, Inbred Strains; Receptors, Purinergic; Time Factors; Uric Acid

1990
Further characterization of adenosine transport in renal brush-border membranes.
    Biochimica et biophysica acta, 1990, May-24, Volume: 1024, Issue:2

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Caffeine; Hypoxanthine; Hypoxanthines; Kidney Tubules, Proximal; Kinetics; Microvilli; Rats; Rats, Inbred Strains; Sodium; Substrate Specificity

1990
Sixth International Caffeine Workshop, Hong Kong, 7-10 August 1989.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1990, Volume: 28, Issue:4

    Topics: Adenosine; Animals; Arrhythmias, Cardiac; Bone Development; Caffeine; DNA Replication; Female; Humans; Mental Processes; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction

1990
Adenosine inhibits the rise in intracellular calcium and platelet aggregation produced by thrombin: evidence that both effects are coupled to adenylate cyclase.
    Molecular pharmacology, 1990, Volume: 37, Issue:6

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Caffeine; Calcium; Cytosol; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Xanthines

1990
Effects of caffeine, L-phenylisopropyladenosine and their combination on local cerebral blood flow in the rat.
    European journal of pharmacology, 1990, Apr-25, Volume: 179, Issue:3

    Topics: Adenosine; Animals; Antipyrine; Blood Pressure; Caffeine; Cerebrovascular Circulation; Drug Interactions; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains

1990
Noncompetitive antagonism of adenosine by caffeine on the hepatic and superior mesenteric arteries of anesthetized cats.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Cats; Chloralose; Dose-Response Relationship, Drug; Drug Interactions; Female; Hepatic Artery; Injections, Intravenous; Isoproterenol; Male; Mesenteric Arteries; Pentobarbital

1990
Caffeine-induced seizures: apparent proconvulsant action of N-ethyl carboxamidoadenosine (NECA).
    Life sciences, 1990, Volume: 47, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Caffeine; Cerebral Ventricles; Dose-Response Relationship, Drug; Male; Mice; Premedication; Receptors, Purinergic; Regression Analysis; Seizures

1990
Modulation of the behavioral effects of chlordiazepoxide by methylxanthines and analogs of adenosine in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Chlordiazepoxide; Conditioning, Psychological; Male; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Saimiri; Theobromine; Theophylline; Xanthines

1985
Behavioral characteristics of centrally administered adenosine analogs.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Caffeine; Dilazep; Dipyridamole; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Motor Activity

1986
Spinal adenosine modulates descending antinociceptive pathways stimulated by morphine.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Analgesia; Animals; Caffeine; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Nociceptors; Spinal Cord; Theophylline; Xanthines

1986
Effect of chronically administered methylxanthines on ethanol-induced motor incoordination in mice.
    Life sciences, 1986, Oct-20, Volume: 39, Issue:16

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Brain; Caffeine; Drug Synergism; Ethanol; Kinetics; Male; Mice; Motor Activity; Receptors, Purinergic; Theophylline; Xanthines

1986
Discriminative stimulus properties of caffeine in the rat: noradrenergic mediation.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adrenergic alpha-Antagonists; Animals; Apomorphine; Avoidance Learning; Caffeine; Clonidine; Diazepam; Discrimination Learning; Male; Norepinephrine; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Theobromine; Theophylline

1986
Paradoxical stimulation of human sperm motility by 2-deoxyadenosine.
    Journal of reproduction and fertility, 1986, Volume: 78, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Caffeine; Calcimycin; Colforsin; Cyclic AMP; Deoxyadenosines; Freezing; Humans; Male; Sperm Motility; Spermatozoa; Stimulation, Chemical

1986
Inhibition of porcine adipose tissue lipogenesis by beta-adrenergic agonists.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1989, Volume: 94, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adipose Tissue; Adrenergic beta-Agonists; Animals; Caffeine; Drug Interactions; Epinephrine; Isoproterenol; Lipids; Male; Propranolol; Swine; Theophylline

1989
Effect of adenosine on gonadotropin and prolactin secretion by hemipituitaries in vitro.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1989, Volume: 22, Issue:6

    Topics: Adenosine; Animals; Caffeine; Culture Media; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; In Vitro Techniques; Luteinizing Hormone; Male; Pituitary Gland; Prolactin; Rats

1989
The role of the purinergic system in the control of stereotypy: relationship to D-1/D-2 dopamine receptor activity.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzazepines; Caffeine; Carbamazepine; Dopamine Antagonists; Drug Interactions; Electroencephalography; Haloperidol; Male; Rabbits; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic; Stereotyped Behavior

1989
Relationship of plasma and brain concentrations of caffeine and metabolites to benzodiazepine receptor binding and locomotor activity.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Adenosine; Animals; Brain; Caffeine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flumazenil; Male; Mice; Motor Activity; Receptors, GABA-A

1989
Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Alprazolam; Anxiety; Caffeine; Chlordiazepoxide; Clonidine; Flumazenil; Motor Activity; Muscle Relaxants, Central; Norepinephrine; Propranolol; Receptors, Adrenergic; Receptors, GABA-A; Receptors, Purinergic; Social Behavior

1989
Comparison of motility stimulants for cryopreserved human semen.
    Fertility and sterility, 1989, Volume: 52, Issue:3

    Topics: Adenosine; Animals; Caffeine; Calcium; Cricetinae; Cyclic AMP; Deoxyadenosines; Female; Humans; Kallikreins; Male; Pentoxifylline; Relaxin; Semen Preservation; Sperm Motility; Sperm-Ovum Interactions

1989
Xylazine-evoked depression of rat cerebral cortical neurons: a pharmacological study.
    General pharmacology, 1989, Volume: 20, Issue:4

    Topics: Acetylcholine; Adenosine; Animals; Caffeine; Cerebral Cortex; Depression, Chemical; In Vitro Techniques; Male; Neural Inhibition; Neurons; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Thiazines; Xylazine

1989
Alpha 2-adrenergic, kappa-opiate, and P1-purinergic autoreceptors have mutually antagonistic effects: a new regulatory mechanism?
    Journal of neurochemistry, 1989, Volume: 53, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzofurans; Caffeine; Calcium; Cerebral Cortex; Clonidine; Dioxanes; Fluorescent Dyes; Fura-2; Homeostasis; Idazoxan; Male; Naloxone; Phenylisopropyladenosine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Purinergic; Synaptosomes

1989
Methyl xanthines enhance taste: evidence for modulation of taste by adenosine receptor.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adult; Animals; Caffeine; Female; Humans; In Vitro Techniques; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Taste; Theobromine; Theophylline; Xanthines

1985
The effect of adenosine and adenosine analogues on methylxanthine-induced hypercalciuria in the rat.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:10

    Topics: Adenosine; Animals; Body Weight; Caffeine; Calcium; Diet; Diuresis; Male; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Xanthines

1989
Modulatory effects of adenosine on baroreflex activation in the brainstem of normotensive rats.
    European journal of pharmacology, 1989, Dec-12, Volume: 174, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Brain Stem; Caffeine; Cisterna Magna; Heart Rate; Injections; Male; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex

1989
Caffeine potentiates the renin response to furosemide in rats. Evidence for a regulatory role of endogenous adenosine.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:1

    Topics: Adenosine; Animals; Caffeine; Drug Synergism; Furosemide; Kidney; Male; Rats; Rats, Inbred Strains; Renin; Xanthines

1989
Differential expression of the ICF (immunodeficiency, centromeric heterochromatin, facial anomalies) mutation in lymphocytes and fibroblasts.
    Journal of medical genetics, 1989, Volume: 26, Issue:7

    Topics: Adenosine; Caffeine; Centromere; Child, Preschool; Chromosome Aberrations; Chromosomes; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; Facial Expression; Female; Fibroblasts; Folic Acid; Humans; Immunologic Deficiency Syndromes; Lymphocytes; Mutation; Thymidine

1989
Carbamazepine, but not caffeine, is highly selective for adenosine A1 binding sites.
    European journal of pharmacology, 1989, May-19, Volume: 164, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Carbamazepine; Cerebellum; Corpus Striatum; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic

1989
Adenosine-angiotensin II interactions. Part II. The role of adenosine in regulating angiotensin II-induced changes in heart rate and aldosterone release.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:2

    Topics: Adenosine; Aldosterone; Angiotensin II; Animals; Blood Pressure; Caffeine; Heart Rate; Male; Rats; Rats, Inbred Strains; Xanthines

1989
Assessment of the role of A1/A2 adenosine receptors mediating the purine antinociception, motor and autonomic function in the rat spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autonomic Nervous System; Blood Pressure; Caffeine; Male; Movement; Pain; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Spinal Cord; Urinary Bladder

1989
Methodological approach to pharmacodynamic calculations of vascular responses in vivo.
    Proceedings of the Western Pharmacology Society, 1989, Volume: 32

    Topics: Adenosine; Animals; Caffeine; Cats; Dose-Response Relationship, Drug; Hemodynamics; Liver Circulation; Vascular Resistance

1989
Caffeine and premenstrual syndrome.
    American journal of public health, 1989, Volume: 79, Issue:12

    Topics: Adenosine; Animals; Caffeine; Female; Humans; Premenstrual Syndrome; Rats

1989
Inhibitory effects of carbamazepine on clonidine-induced aggressive behavior in mice.
    The International journal of neuroscience, 1988, Volume: 42, Issue:1-2

    Topics: Adenosine; Aggression; Animals; Behavior, Animal; Caffeine; Carbamazepine; Clonidine; Haloperidol; Male; Mice; Prazosin; Receptors, Cell Surface; Yohimbine

1988
The effect of caffeine, adenosine, and buffer ionic composition on the induction of cell-surface cAMP binding during starvation of Dictyostelium discoideum.
    Developmental genetics, 1988, Volume: 9, Issue:4-5

    Topics: Adenosine; Buffers; Caffeine; Cyclic AMP; Dictyostelium; Kinetics; Receptors, Cyclic AMP

1988
The role of adenosine in cerebral vascular regulation during reductions in perfusion pressure.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:6

    Topics: Adenosine; Animals; Blood Gas Analysis; Blood Pressure; Caffeine; Cerebrovascular Circulation; Injections, Intraperitoneal; Male; Perfusion; Rats; Rats, Inbred Strains; Vascular Resistance

1986
Inhibitory neuromodulators do not alter the course of experimental hepatic encephalopathy.
    Metabolic brain disease, 1988, Volume: 3, Issue:3

    Topics: Adenosine; Animals; Caffeine; Cerebral Ventricles; Glycine; Hepatic Encephalopathy; Injections, Intraperitoneal; Injections, Intraventricular; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Strychnine

1988
Fanconi's anemia lymphocytes: effect of caffeine, adenosine and niacinamide during G2 prophase.
    Mutation research, 1988, Volume: 199, Issue:1

    Topics: Adenosine; Anemia, Aplastic; Caffeine; Chromosome Aberrations; DNA Repair; Fanconi Anemia; Humans; In Vitro Techniques; Interphase; Lymphocytes; NAD; Niacinamide

1988
Chlorpromazine and trifluoperazine potentiate the action of adenosine on rat cerebral cortical neurons.
    General pharmacology, 1985, Volume: 16, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Cerebral Cortex; Chlorpromazine; Depression, Chemical; Drug Synergism; Iontophoresis; Male; Rats; Rats, Inbred Strains; Synaptic Transmission; Synaptosomes; Trifluoperazine; Vasodilator Agents

1985
Interactive effects of caffeine, 2-chloroadenosine and haloperidol on activity, social investigation and play fighting of juvenile rats.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:3

    Topics: 2-Chloroadenosine; Adenosine; Aggression; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Humans; Male; Motor Activity; Rats; Receptors, Cell Surface; Receptors, Purinergic; Social Behavior

1985
On the mechanism of action of theophylline and caffeine.
    Acta medica Scandinavica, 1985, Volume: 217, Issue:2

    Topics: Adenosine; Asthma; Caffeine; Calcium; Cyclic AMP; Humans; Muscle Contraction; Receptors, Cell Surface; Receptors, Purinergic; Theophylline

1985
Effects of (-)-N6-(R-phenylisopropyl)-adenosine (PIA) and caffeine on nociception and morphine-induced analgesia, tolerance and dependence in mice.
    European journal of pharmacology, 1985, Jun-07, Volume: 112, Issue:2

    Topics: Adenosine; Analgesics; Animals; Brain; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Humans; Male; Mice; Morphine; Morphine Dependence; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic

1985
Influence of cyclic AMP and hydrolysis products on cell type regulation in Dictyostelium discoideum.
    Journal of embryology and experimental morphology, 1985, Volume: 86

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acid Phosphatase; Adenine; Adenosine; Caffeine; Cell Differentiation; Cyclic AMP; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Isoenzymes; Spores, Fungal

1985
Effects of caffeine and 8-phenyltheophylline on the actions of purines and opiates in the guinea-pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1

    Topics: Adenosine; Animals; Caffeine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Nalorphine; Norepinephrine; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Theophylline

1986
Stereoselective behavioral effects of N6-phenylisopropyl-adenosine and antagonism by caffeine.
    Psychopharmacology, 1985, Volume: 87, Issue:3

    Topics: Adenosine; Animals; Caffeine; Color; Conditioning, Operant; Food; Male; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, Purinergic; Reinforcement Schedule; Stereoisomerism

1985
Chronic caffeine ingestion sensitizes the A1 adenosine receptor-adenylate cyclase system in rat cerebral cortex.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:1

    Topics: Adenosine; Adenylyl Cyclases; Animals; Caffeine; Cerebral Cortex; Cross-Linking Reagents; Guanine Nucleotides; Kinetics; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Purinergic; Substance Withdrawal Syndrome; Time Factors

1986
Cross-tolerance studies between caffeine and (-)-N6-(phenylisopropyl)-adenosine (PIA) in mice.
    Life sciences, 1986, Feb-17, Volume: 38, Issue:7

    Topics: Adenosine; Animals; Body Weight; Caffeine; Dose-Response Relationship, Drug; Drinking; Drug Tolerance; Kinetics; Male; Methamphetamine; Mice; Motor Activity; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic

1986
Caffeine intensifies taste of certain sweeteners: role of adenosine receptor.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Adenosine; Adult; Caffeine; Drug Synergism; Female; Humans; Male; Receptors, Cell Surface; Receptors, Purinergic; Sweetening Agents; Taste

1986
The xanthine derivative 1-(5'-oxohexyl)-3-methyl-7-propyl xanthine (HWA 285) enhances the actions of adenosine.
    Acta pharmacologica et toxicologica, 1986, Volume: 58, Issue:3

    Topics: Adenosine; Animals; Biological Transport; Caffeine; Cyclic AMP; Drug Synergism; Erythrocyte Membrane; Hippocampus; Humans; Pentoxifylline; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Theobromine; Xanthines

1986
Analogs of caffeine: antagonists with selectivity for A2 adenosine receptors.
    Life sciences, 1986, Aug-25, Volume: 39, Issue:8

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Caffeine; Humans; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship

1986
Chronic caffeine treatment reduces caffeine but not adenosine effects on cortical acetylcholine release.
    British journal of pharmacology, 1986, Volume: 88, Issue:3

    Topics: Acetylcholine; Adenosine; Animals; Body Weight; Caffeine; Cerebral Cortex; Electric Stimulation; Exploratory Behavior; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic

1986
Adenosine in renin-dependent renovascular hypertension.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 12, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Hypertension, Renovascular; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Renin; Renin-Angiotensin System; Time Factors

1988
Ro 15-1788 both antagonizes and potentiates adenosine-evoked depression of cerebral cortical neurons.
    European journal of pharmacology, 1987, Apr-14, Volume: 136, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Cerebral Cortex; Evoked Potentials; Flumazenil; Male; Rats; Rats, Inbred Strains

1987
Psychomotor stimulant effects of methylxanthines in squirrel monkeys: relation to adenosine antagonism.
    Psychopharmacology, 1988, Volume: 95, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Male; Psychomotor Performance; Receptors, Purinergic; Saimiri; Stimulation, Chemical; Theophylline; Xanthines

1988
3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs.
    Life sciences, 1988, Volume: 43, Issue:21

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Body Temperature; Caffeine; Male; Mice; Mice, Inbred DBA; Motor Activity; Reference Values; Theobromine; Theophylline

1988
Purinergic modulation of cortical acetylcholine release is decreased in aging rats.
    Experimental gerontology, 1988, Volume: 23, Issue:3

    Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Caffeine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Parietal Lobe; Rats; Rats, Inbred Strains

1988
Differences in adenosine A-1 and A-2 receptor density revealed by autoradiography in methylxanthine-sensitive and insensitive mice.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autoradiography; Brain; Caffeine; Male; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Organ Specificity; Receptors, Purinergic; Species Specificity; Tritium

1988
Effects of chronic administration of caffeine on adenosine A1 and A2 receptors in rat brain.
    Brain research bulletin, 1988, Volume: 21, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Caffeine; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic

1988
Comparative effects of caffeine and L-phenylisopropyladenosine on local cerebral glucose utilization in the rat.
    European journal of pharmacology, 1988, Nov-15, Volume: 157, Issue:1

    Topics: Adenosine; Animals; Brain; Caffeine; Carbon Radioisotopes; Drug Synergism; Glucose; Humans; Locomotion; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains

1988
Role of endogenous adenosine as a modulator of the renin response to salt restriction.
    Nephrologie, 1987, Volume: 8, Issue:6

    Topics: Adenosine; Animals; Caffeine; Diet, Sodium-Restricted; Glomerular Filtration Rate; Humans; Male; Potassium; Rats; Rats, Inbred Strains; Receptors, Purinergic; Renal Circulation; Renin; Sodium; Xanthines

1987
Comparative influence of calcium blocker and purinergic drugs on epileptiform bursting in rat hippocampal slices.
    Brain research, 1988, Feb-16, Volume: 441, Issue:1-2

    Topics: Adenosine; Animals; Caffeine; Calcium; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Neurons; Nifedipine; Phenylisopropyladenosine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Verapamil

1988
Effects of adenosine analogs alone and in combination with caffeine in the squirrel monkey.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Caffeine; Conditioning, Operant; Drug Interactions; Male; Motor Activity; Phenylisopropyladenosine; Receptors, Purinergic; Saimiri

1988
Anticonvulsant activity of carbamazepine and N6-L-phenylisopropyladenosine in rabbits. Relationship to adenosine receptors in central nervous system.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:3

    Topics: Adenosine; Animals; Anticonvulsants; Caffeine; Carbamazepine; Central Nervous System; Drug Interactions; Electroencephalography; Male; Pentylenetetrazole; Phenylisopropyladenosine; Rabbits; Receptors, Purinergic; Seizures

1988
Tolerance and cross-tolerance to theophylline-induced stimulation of locomotor activity in rats.
    Life sciences, 1988, Volume: 42, Issue:24

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Dextroamphetamine; Drug Tolerance; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline

1988
Endogenous adenosine and hemorrhagic shock: effects of caffeine administration or caffeine withdrawal.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:12

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Male; Rats; Rats, Inbred Strains; Shock, Hemorrhagic; Substance Withdrawal Syndrome; Time Factors

1988
Potentiation of the anti-lipolytic effect of 2-chloroadenosine after chronic caffeine treatment.
    Pharmacology, 1988, Volume: 36, Issue:5

    Topics: 2-Chloroadenosine; Adenosine; Adipose Tissue; Animals; Body Weight; Caffeine; Cell Membrane; Drug Synergism; In Vitro Techniques; Lipolysis; Male; Organ Size; Radioligand Assay; Rats; Rats, Inbred Strains; Xanthines

1988
Endogenous adenosine inhibits hippocampal CA1 neurones: further evidence from extra- and intracellular recording.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:5

    Topics: Adenosine; Adenosine Deaminase; Animals; Caffeine; Electrophysiology; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Neurons; Rats; Rats, Inbred Strains; Thioinosine

1988
Interactions between caffeine and adenosine agonists in producing embryo resorptions and malformations in mice.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:3

    Topics: 2-Chloroadenosine; Abnormalities, Drug-Induced; Adenosine; Animals; Body Weight; Caffeine; Drug Administration Schedule; Drug Synergism; Embryo Loss; Female; Fetal Death; Mice; Mice, Inbred Strains; Phenylisopropyladenosine; Pregnancy

1987
Stimulation of glycogenolysis in isolated hepatocytes by adenosine and one of its analogues is inhibited by caffeine.
    The Biochemical journal, 1987, Nov-01, Volume: 247, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Cell Separation; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; In Vitro Techniques; Liver; Liver Glycogen; Male; Phenylisopropyladenosine; Phosphorylases; Rats; Rats, Inbred Strains; Stimulation, Chemical

1987
An involvement of adenosine in cerebral blood flow regulation during hypercapnia.
    General pharmacology, 1987, Volume: 18, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Cerebrovascular Circulation; Coformycin; Dipyridamole; Hypercapnia; Male; Pentostatin; Rats; Rats, Inbred Strains

1987
Effects of N6-(L-phenylisopropyl)adenosine, caffeine, theophylline and rolipram on the acquisition of conditioned responses in the rabbit.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Adenosine; Animals; Caffeine; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Phenylisopropyladenosine; Pyrrolidinones; Rabbits; Rolipram; Theophylline

1987
Behavioral and cardiovascular effects of analogs of adenosine in cynomolgus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Blood Pressure; Caffeine; Cardiovascular System; Clonidine; Cocaine; Dextroamphetamine; Heart Rate; Isomerism; Macaca fascicularis; Male; Phenylisopropyladenosine

1987
Central effects of adenosine analogs on blood pressure and heart rate in the mouse.
    The Canadian journal of cardiology, 1987, Volume: 3, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Phenylisopropyladenosine

1987
Psychomotor stimulant effects of caffeine alone and in combination with an adenosine analog in the squirrel monkey.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1

    Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Food; Male; Motor Activity; Saimiri

1987
A1- and A2-selective adenosine antagonists: in vivo characterization of cardiovascular effects.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Heart Rate; Male; Mice; Mice, Inbred Strains; Nicotine; Receptors, Purinergic

1987
Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat.
    Neuroscience, 1987, Volume: 22, Issue:2

    Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Caffeine; Cats; Dipyridamole; Injections, Intravenous; Iontophoresis; Naloxone; Neurons; Spinal Cord; Strychnine; Theophylline; Vibration

1987
Effects of caffeine and L-phenylisopropyladenosine on locomotor activity of mice.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:2

    Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Phenylisopropyladenosine; Time Factors; Tritium

1987
Effects of 2-chloroadenosine on hippocampal GABA content and turnover.
    Journal of neural transmission, 1986, Volume: 65, Issue:3-4

    Topics: 2-Chloroadenosine; 4-Aminobutyrate Transaminase; Adenosine; Aminooxyacetic Acid; Animals; Caffeine; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraventricular; Kinetics; Male; Rats; Rats, Inbred Strains

1986
Reduction of liver plasma flow by caffeine and theophylline.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:5

    Topics: Adenosine; Adult; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Humans; Indocyanine Green; Kinetics; Liver Circulation; Male; Middle Aged; Norepinephrine; Theophylline

1986
Effects of selected analogs of adenosine on schedule-controlled behavior in rats.
    Neuropharmacology, 1986, Volume: 25, Issue:10

    Topics: Adenosine; Animals; Caffeine; Chlordiazepoxide; Conditioning, Operant; Drug Interactions; Drug Tolerance; Levorphanol; Male; Phenylisopropyladenosine; Rats; Reaction Time; Reinforcement Schedule

1986
Antagonism of the cardiovascular effects of adenosine by caffeine or 8-(p-sulfophenyl)theophylline.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:2

    Topics: Adenosine; Blood Pressure; Brain; Caffeine; Heart Rate; Hemodynamics; Receptors, Purinergic; Theophylline

1987
Behavioral effects of caffeine, (-)N-((R)-1-methyl-2-phenylethyl)-adenosine (PIA), and their combination in the mouse.
    Psychopharmacology, 1985, Volume: 87, Issue:4

    Topics: Adenosine; Animals; Caffeine; Conditioning, Operant; Drug Interactions; Food; Light; Male; Mice; Reinforcement Schedule; Sound

1985
Effect of adenosine, adenosine derivatives, and caffeine on acetylcholine release from brain synaptosomes: interaction with muscarinic autoregulatory mechanisms.
    Journal of neurochemistry, 1986, Volume: 46, Issue:5

    Topics: Acetylcholine; Adenosine; Animals; Brain; Caffeine; Cerebral Cortex; Hippocampus; Male; Oxotremorine; Physostigmine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes

1986
Effect of caffeine and adenosine on G2 repair: mitotic delay and chromosome damage.
    Mutation research, 1985, Volume: 149, Issue:2

    Topics: Adenosine; Caffeine; Chromosomes; DNA Repair; Interphase; Mitosis; Plants; Uracil

1985
Effects of caffeine and L-PIA on rats with selective damage of the hippocampal system.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:3

    Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Colchicine; Conditioning, Operant; Dose-Response Relationship, Drug; Hippocampus; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Time Factors

1985
Adenosine antagonists. Lack of effect on the inhibition of kindled seizures in rats by carbamazepine.
    Neuropharmacology, 1985, Volume: 24, Issue:7

    Topics: Adenosine; Animals; Caffeine; Carbamazepine; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Seizures; Theophylline

1985
Effects of caffeine on hippocampal pyramidal cells in vitro.
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: Adenosine; Animals; Caffeine; Calcium; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neural Conduction; Neurons; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin

1985
Protective effect of adenosine and nicotinamide against audiogenic seizure.
    Biochemical pharmacology, 1974, Oct-15, Volume: 23, Issue:20

    Topics: Acoustic Stimulation; Adenosine; Adenosine Triphosphate; Animals; Blood Pressure; Brain Chemistry; Caffeine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred Strains; NAD; Niacinamide; Norepinephrine; Phosphocreatine; Phosphorus Radioisotopes; Time Factors

1974
Repression of alkaline phosphatase synthesis by adenine, adenosine and adenine nucleotides in an adenine auxotroph of Bacillus anthracis.
    Acta microbiologica Academiae Scientiarum Hungaricae, 1973, Volume: 20, Issue:3

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Alkaline Phosphatase; Bacillus anthracis; Caffeine; Chlorpromazine; Culture Media; Dinitrophenols; Enzyme Repression; Inosine Nucleotides; Lyases; Mutation; Phosphates; Theophylline

1973
The determination of nikethamide and other compounds in pharmaceutical dosage forms by thin-layer chromatography.
    The Analyst, 1971, Volume: 96, Issue:147

    Topics: Adenosine; Caffeine; Chromatography, Thin Layer; Dosage Forms; Gels; Methods; Niacinamide; Silicon Dioxide; Solvents; Spectrophotometry; Strychnine; Theophylline; Ultraviolet Rays

1971
Significance of the caffeine-like effect of various purines, pyrimidines and derivatives on adipose-tissue phosphodiesterase.
    The Biochemical journal, 1971, Volume: 124, Issue:2

    Topics: Adenine; Adenosine; Adipose Tissue; Animals; Caffeine; Deoxyadenosines; Epididymis; Guanosine; Male; Phosphoric Monoester Hydrolases; Purines; Pyrimidines; Rats

1971
Methyl xantines in the inhibition of platelet aggregation.
    Acta medica Scandinavica. Supplementum, 1971, Volume: 525

    Topics: Adenosine; Aminophylline; Blood Platelets; Caffeine; Cell Aggregation; Cyclic AMP; Norepinephrine; Tritium; Xanthines

1971
Aggregation of human blood platelets by vasopressin.
    The American journal of physiology, 1972, Volume: 223, Issue:4

    Topics: Acetates; Adenosine; Animals; Anticoagulants; Blood Platelets; Caffeine; Carbon Isotopes; Cations, Divalent; Cell Aggregation; Chelating Agents; Citrates; Creatine Kinase; Cyclic AMP; Dogs; Ethylmaleimide; Fibrinogen; Glycols; Hirudins; Humans; Imipramine; Phosphocreatine; Prostaglandins; Rabbits; Serotonin; Swine; Vasopressins

1972
Effects of antilipolytic agents and alpha-adrenergic antagonists on cyclic AMP metabolism in hamster white adipocytes.
    Biochimica et biophysica acta, 1973, Sep-25, Volume: 316, Issue:3

    Topics: 1-Propanol; Adenosine; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Caffeine; Cricetinae; Cyclic AMP; Epididymis; Epinephrine; Male; Nicotinic Acids; Norepinephrine; Phenoxybenzamine; Phentolamine; Prostaglandins; Pyrazoles; Tritium

1973
Effect of certain halogenated hydrocarbon insecticides on cyclic adenosine 3',5'-monophosphate-3H formation by rat kidney cortex.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 188, Issue:1

    Topics: Adenosine; Adenylyl Cyclases; Animals; Caffeine; Chlordan; Cyclic AMP; DDT; Dieldrin; Dose-Response Relationship, Drug; Drug Synergism; Endrin; Heptachlor; Hydrazines; Imidazoles; Insecticides; Kidney Cortex; Male; Phosphoric Diester Hydrolases; Propranolol; Prostaglandins; Rats; Tritium

1974
Interactions of the pharmacological receptors of blood platelets with adenylate cyclase.
    Series haematologica (1968), 1973, Volume: 6, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Binding Sites; Blood Platelets; Caffeine; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Thin Layer; Cyclic AMP; Enzyme Activation; Epinephrine; Humans; Isoproterenol; Papaverine; Platelet Adhesiveness; Prostaglandins; Receptors, Adrenergic; Stimulation, Chemical; Sympatholytics; Time Factors

1973
Inhibition of platelet adherence to a collagen-coated surface by agents that inhibit platelet shape change and clot retraction.
    The Journal of laboratory and clinical medicine, 1974, Volume: 84, Issue:4

    Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Caffeine; Carbon Radioisotopes; Chromium Radioisotopes; Clot Retraction; Colchicine; Collagen; Cyclic AMP; Cytochalasin B; Maleimides; Mercuribenzoates; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Prostaglandins; Serotonin; Sulfhydryl Compounds; Sulfonic Acids; Swine

1974
The aggregation of rabbit polymorphonuclear leucocytes: effects of antimitotic agents, cyclic nucleotides and methyl xanthines.
    Journal of cell science, 1974, Volume: 16, Issue:1

    Topics: Adenine; Adenosine; Animals; Bucladesine; Caffeine; Cell Aggregation; Colchicine; Cyclic AMP; Cyclic GMP; Depression, Chemical; In Vitro Techniques; Leukocytes; Nucleotides, Cyclic; Rabbits; Stimulation, Chemical; Theobromine; Theophylline; Vinblastine; Xanthines

1974
Studies on lipolysis in lipid micelles isolated from adipose tissue.
    Journal of biochemistry, 1974, Volume: 75, Issue:6

    Topics: Adenosine; Adenosine Monophosphate; Adipose Tissue; Animals; Bucladesine; Caffeine; Colloids; Cyclic AMP; Epididymis; Epinephrine; In Vitro Techniques; Lipid Metabolism; Macromolecular Substances; Male; Phospholipases; Rats; Theophylline

1974
Structure-activity relations for caffeine: a comparative study of the inotropic effects of the methylxanthines, imidazoles and related compounds on the frog's heart.
    The Journal of physiology, 1974, Volume: 242, Issue:3

    Topics: Adenosine; Animals; Caffeine; Cyclic AMP; Dose-Response Relationship, Drug; Heart; Heart Atria; Histamine; Histidine; Hydrogen-Ion Concentration; Hypoxanthines; Imidazoles; In Vitro Techniques; Naphazoline; Phentolamine; Pilocarpine; Potassium; Pyridines; Rana pipiens; Solutions; Structure-Activity Relationship; Surface Tension; Theobromine; Theophylline; Tolazoline; Xanthines

1974
Theophylline inhibition of nucleoside transport and its relation to cyclic AMP in skeletal muscle.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:6

    Topics: Adenine; Adenosine; Animals; Biological Transport; Bucladesine; Caffeine; Carbon Radioisotopes; Chromatography, Paper; Cyclic AMP; Hypoxanthines; In Vitro Techniques; Inosine; Isoproterenol; Muscle Contraction; Muscles; Nucleosides; Phenytoin; Propranolol; Protein Binding; Purines; Rana pipiens; Ribose; Sorbitol; Theophylline; Tritium; Uridine

1974
Cyclic AMP-induced tyrosinase synthesis in Neurospora crassa.
    Biochemical and biophysical research communications, 1974, Dec-11, Volume: 61, Issue:3

    Topics: Adenine; Adenosine; Adenosine Monophosphate; Bucladesine; Caffeine; Catechol Oxidase; Cyclic AMP; Cycloheximide; Enzyme Induction; Neurospora; Neurospora crassa; Theophylline

1974
Chlorpromazine-induced contracture of frog rectus abdominis muscle.
    Pharmacology, 1974, Volume: 12, Issue:1

    Topics: Acetylcholine; Adenosine; Animals; Arsenic; Atropine; Caffeine; Chlorpromazine; Choline; Cocaine; Cyanides; Electric Stimulation; Fluorides; Hexamethonium Compounds; In Vitro Techniques; Iodoacetates; Muscle Contraction; Ouabain; Physostigmine; Potassium Chloride; Procaine; Quinine; Sparteine; Stimulation, Chemical; Tubocurarine

1974
[The effect of methylxanthines on catecholamine and adenylate nucleotide concentration in rat myocardium].
    Biulleten' eksperimental'noi biologii i meditsiny, 1974, Volume: 78, Issue:10

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Caffeine; Inosine; Inosine Nucleotides; Myocardium; Phosphorus; Rats; Stimulation, Chemical; Strophanthins; Theobromine; Theophylline; Tyramine; Xanthines

1974
[Comparative investigation on the vitro inhibition of adenosine decomposition by dilazep].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:11A Suppl

    Topics: Adenosine; Adult; Azepines; Benzoates; Caffeine; Cell Membrane Permeability; Dipyridamole; Drug Interactions; Erythrocytes; Ethylenediamines; Humans; In Vitro Techniques; Lidoflazine; Theophylline; Vasodilator Agents

1974
Adenosine uptake by isolated membrane vesicles from Escherichia coli K-12.
    Biochimica et biophysica acta, 1973, Dec-13, Volume: 330, Issue:2

    Topics: Adenine; Adenosine; Ascorbic Acid; Azides; Biological Transport, Active; Caffeine; Carbon Radioisotopes; Cell Membrane; Chloromercuribenzoates; Escherichia coli; Iodoacetates; Kinetics; Maleimides; Microscopy, Electron; Mutation; Organoids; Phenazines; Ribonucleosides; Time Factors

1973
On the mechanism of the antagonistic action of xanthine derivatives against adenosine and coronary vasodilators.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:8

    Topics: Acetamides; Adenosine; Animals; Blood Flow Velocity; Caffeine; Cell Membrane Permeability; Coronary Vessels; Coumarins; Dipyridamole; Dogs; Drug Interactions; Erythrocytes; Female; Glycolates; Humans; Male; Piperazines; Receptors, Drug; Structure-Activity Relationship; Theophylline; Vasodilator Agents; Xanthines; Xylenes

1972
Inhibition of the negative chronotropic action of adenosine by caffeine in the dog.
    European journal of pharmacology, 1973, Volume: 21, Issue:3

    Topics: Acetylcholine; Action Potentials; Adenosine; Animals; Caffeine; Calcium; Dogs; Female; Heart Rate; Male; Norepinephrine; Pacemaker, Artificial; Sinoatrial Node; Time Factors

1973
Effects of amines on the level of N-acetyl-aspartate and N-acetyl-aspartyl-glutamate in mouse brain tissue slices.
    Journal of neurochemistry, 1971, Volume: 18, Issue:11

    Topics: Acetylcholine; Adenosine; Amines; Amino Acids; Amino Alcohols; Aminobutyrates; Animals; Aspartic Acid; Basal Ganglia; Biogenic Amines; Brain; Caffeine; Cerebellum; Cerebral Cortex; Dipeptides; Dopamine; Edetic Acid; Glutamates; Glycine; Histamine; Medulla Oblongata; Mice; Norepinephrine; Pons; Puromycin; Serotonin; Spermine; Taurine

1971
Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system.
    Epilepsia, 1984, Volume: 25, Issue:4

    Topics: Adenosine; Animals; Anticonvulsants; Brain; Caffeine; Carbamazepine; Cerebellum; Cerebral Cortex; Cyclic AMP; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline

1984
Tolerance to N6-(L-phenylisopropyl) adenosine. Contribution of behavioral mechanisms and cross-tolerance profile.
    Neuropharmacology, 1984, Volume: 23, Issue:6

    Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic

1984
Adenosine analogs: potentiation of bradykinin-induced plasma exudation in rat skin and prevention by caffeine and theophylline.
    Life sciences, 1984, Oct-08, Volume: 35, Issue:15

    Topics: Adenosine; Animals; Bradykinin; Caffeine; Capillary Permeability; Cyproheptadine; Drug Synergism; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Skin; Theophylline

1984
Purine involvement in morphine antinociception.
    British journal of pharmacology, 1984, Volume: 83, Issue:4

    Topics: 2-Chloroadenosine; Adenosine; Analgesia; Animals; Body Temperature; Bucladesine; Caffeine; Male; Morphine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains

1984
Adenosine mediates sedative action of various centrally active drugs.
    Medical hypotheses, 1982, Volume: 9, Issue:4

    Topics: Adenosine; Animals; Antipsychotic Agents; Arousal; Brain; Caffeine; Diazepam; Hypnotics and Sedatives; Phenothiazines; Rats; Receptors, Cell Surface; Receptors, Purinergic; Synapses; Synaptic Transmission; Synaptosomes; Theophylline

1982
Interactions between catecholamines, methyl xanthines and adenosine in regulation of cyclic AMP accumulation in hamster adipocytes.
    Biochimica et biophysica acta, 1980, Apr-17, Volume: 629, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Caffeine; Catecholamines; Cricetinae; Cyclic AMP; Epinephrine; Isoproterenol; Mesocricetus; Norepinephrine; Phentolamine; Theophylline

1980
Methylxanthines modulate adenosine release from slices of cerebral cortex.
    Brain research, 1981, Mar-02, Volume: 207, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine Triphosphatases; Aminophylline; Animals; Caffeine; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Male; Mice; Ouabain; Theophylline; Xanthines

1981
Interactions in the behavioral effects of methylxanthines and adenosine derivatives.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Brain; Caffeine; Cardiac Complexes, Premature; Diazepam; Drug Interactions; Heart Rate; Male; Mice; Mice, Inbred ICR; Motor Activity; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Stimulation, Chemical; Xanthines

1983
Inhibition of the transport of adenosine, other nucleosides and hypoxanthine in novikoff rat hepatoma cells by methylxanthines, papaverine, N6-cyclohexyladenosine and N6-phenylisopropyladenosine.
    Biochemical pharmacology, 1984, Jun-01, Volume: 33, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Biological Transport, Active; Caffeine; Cell Line; Hypoxanthine; Hypoxanthines; Liver Neoplasms, Experimental; Papaverine; Phenylisopropyladenosine; Rats; Theophylline; Uridine; Xanthines

1984
Behavioral and molecular actions of caffeine: focus on adenosine.
    Journal of psychiatric research, 1984, Volume: 18, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anxiety Disorders; Behavior; Caffeine; Child; Cyclic AMP; Diagnosis, Differential; Humans; Male; Phenylisopropyladenosine; Psychomotor Performance; Rats; Receptors, Cell Surface; Receptors, Purinergic; Seizures; Sleep Initiation and Maintenance Disorders; Stimulation, Chemical; Tea; Xanthines

1984
Behavioral interaction of adenosine and methylxanthines on central purinergic systems.
    Neuroscience letters, 1984, Jun-15, Volume: 47, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Caffeine; Drug Interactions; Male; Mice; Mice, Inbred ICR; Motor Activity; Papaverine; Theophylline

1984
Effects of antimutagens on prophage induction in E coli lysogenic for lambda.
    Environmental mutagenesis, 1983, Volume: 5, Issue:1

    Topics: Acriflavine; Adenosine; Aminoacridines; Bacteriophage lambda; Caffeine; DNA Repair; Escherichia coli; Quinacrine; Spermine; Ultraviolet Rays; Virus Activation

1983
Purine antagonists in the identification of adenosine-receptors in guinea-pig trachea and the role of purines in non-adrenergic inhibitory neurotransmission.
    British journal of pharmacology, 1980, Volume: 69, Issue:3

    Topics: Adenosine; Animals; Caffeine; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Phenoxybenzamine; Phentolamine; Purines; Quinidine; Receptors, Drug; Synaptic Transmission; Trachea; Xanthines

1980
Effects of caffeine and theophylline on adenosine and benzodiazepine receptors in human brain.
    Neuroscience letters, 1982, May-28, Volume: 30, Issue:2

    Topics: Adenosine; Binding, Competitive; Brain; Caffeine; Diazepam; Humans; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Purinergic; Theophylline; Xanthines

1982
Adenosine actions and adenosine receptors after 1 week treatment with caffeine.
    Acta physiologica Scandinavica, 1982, Volume: 115, Issue:2

    Topics: Adenosine; Adipose Tissue; Animals; Caffeine; Cyclic AMP; Dose-Response Relationship, Drug; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Time Factors

1982
[Purinergic effect of ethymisole].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 94, Issue:9

    Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Brain; Caffeine; Cyclic AMP; Drug Interactions; Energy Metabolism; Etimizol; Imidazoles; Rats

1982
Coffee and opiate receptors. Another cup of coffee?
    Nature, 1983, Jan-20, Volume: 301, Issue:5897

    Topics: Adenosine; Animals; Caffeine; Coffee; Guinea Pigs; Humans; Naloxone; Receptors, Cell Surface; Receptors, Opioid; Receptors, Purinergic

1983
Chronic caffeine consumption increases the number of brain adenosine receptors.
    Life sciences, 1983, Mar-07, Volume: 32, Issue:10

    Topics: Adenosine; Animals; Brain; Caffeine; Diazepam; Diet; Mice; Receptors, Cell Surface; Receptors, Purinergic; Xanthines

1983
Discriminative stimulus properties of L-phenylisopropyl adenosine: blockade by caffeine and generalization to 2-chloroadenosine.
    Life sciences, 1983, May-16, Volume: 32, Issue:20

    Topics: 2-Chloroadenosine; Adenosine; Animals; Caffeine; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Psychological; Male; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, Purinergic

1983
Reduction in caffeine toxicity by acetaminophen.
    Journal of toxicology. Clinical toxicology, 1982, Volume: 19, Issue:10

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Acetaminophen; Acoustic Stimulation; Adenosine; Adult; Animals; Brain; Caffeine; Drug Interactions; Female; Humans; Mice; Seizures

1982
Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines.
    Cellular and molecular neurobiology, 1983, Volume: 3, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Brain; Caffeine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theobromine; Theophylline; Xanthines

1983
Evidence for the presence of P1- and P2-purinoceptors in rat caecum.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 264, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Caffeine; Cecum; Cyclic AMP; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Quinidine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline

1983
Effects of chronic caffeine on brain adenosine receptors: regional and ontogenetic studies.
    Life sciences, 1984, Feb-27, Volume: 34, Issue:9

    Topics: Adenosine; Animals; Brain; Brain Stem; Caffeine; Cerebellum; Female; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic; Thioinosine; Time Factors

1984
The synergistic action of caffeine or adenosine on glucose stimulation of liver glycogen synthase phosphatase activity.
    FEBS letters, 1984, May-21, Volume: 170, Issue:2

    Topics: Adenine; Adenosine; Animals; Caffeine; Drug Synergism; Enzyme Activation; Glucose; Glycogen-Synthase-D Phosphatase; Liver; Phosphoprotein Phosphatases; Rats

1984
Hormone and methylxanthine action on breast epithelial cells.
    Life sciences, 1984, Jun-18, Volume: 34, Issue:25

    Topics: 2-Chloroadenosine; Adenosine; Animals; Breast; Breast Neoplasms; Caffeine; Cell Line; Cyclic AMP; Epithelium; Female; Fibrocystic Breast Disease; Humans; Mice; Terbutaline; Xanthines

1984
Caffeine actions and adenosine.
    Psychopharmacology bulletin, 1984,Summer, Volume: 20, Issue:3

    Topics: Adenosine; Animals; Caffeine; Mice; Motor Activity

1984
Biphasic effect of methylxanthines on acetylcholine release from electrically-stimulated brain slices.
    British journal of pharmacology, 1984, Volume: 83, Issue:1

    Topics: Acetylcholine; Adenosine; Aminophylline; Animals; Brain; Caffeine; Dipyridamole; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Xanthines

1984
Potentiation of the action of adenosine on cerebral cortical neurones by the tricyclic antidepressants.
    British journal of pharmacology, 1984, Volume: 83, Issue:2

    Topics: Action Potentials; Adenosine; Animals; Antidepressive Agents, Tricyclic; Caffeine; Cerebral Cortex; Clomipramine; Desipramine; Drug Synergism; Iprindole; Male; Neurons; Nortriptyline; Rats; Rats, Inbred Strains

1984
Antagonism of the behavioral effects of L-phenylisopropyladenosine (L-PIA) by caffeine and its metabolites.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Conditioning, Psychological; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline; Xanthines

1984
Effects of anoxia on cerebral blood flow in the rat brain: evidence for a role of adenosine in autoregulation.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1984, Volume: 4, Issue:4

    Topics: Adenosine; Animals; Brain; Caffeine; Cerebrovascular Circulation; Dipyridamole; Homeostasis; Hypoxia; Injections, Intravenous; Male; Papaverine; Rats; Rats, Inbred Strains; Regional Blood Flow

1984
Behavioral effects of caffeine, N6-(L-phenylisopropyl) adenosine and their combination in the squirrel monkey.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:3

    Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Combinations; Electroshock; Food; Male; Phenylisopropyladenosine; Saimiri

1984
Effect of adenosine and caffeine on acetylcholine release from electrically stimulated brain slices.
    Annali dell'Istituto superiore di sanita, 1984, Volume: 20, Issue:1

    Topics: Acetylcholine; Adenosine; Animals; Caffeine; Cerebral Cortex; Male; Rats; Rats, Inbred Strains

1984
Antagonism of enkephalin action on acetylcholine release by methylxanthines: lack of a purine link.
    British journal of pharmacology, 1983, Volume: 80, Issue:4

    Topics: Acetylcholine; Adenosine; Animals; Caffeine; Cerebral Cortex; Enkephalins; Guinea Pigs; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Rats; Theophylline; Xanthines

1983
Adenosine strongly potentiates pressor responses to nicotine in rats.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:17

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Drug Synergism; Electric Stimulation; Male; Nicotine; Phenylephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Theophylline

1984
Thermoregulatory effects of purines and caffeine.
    Life sciences, 1983, Dec-12, Volume: 33, Issue:24

    Topics: Adenosine; Animals; Body Temperature Regulation; Caffeine; Drug Interactions; Inosine; Male; Purine Nucleosides; Rats; Rats, Inbred Strains

1983
Novel form of drug-dependence--on adenosine in guinea pig ileum.
    Nature, 1983, Apr-14, Volume: 302, Issue:5909

    Topics: Adenosine; Animals; Caffeine; Guinea Pigs; Humans; Ileum; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Substance-Related Disorders; Theophylline

1983
Adenosine modulation of amygdala kindling.
    Experimental neurology, 1984, Volume: 84, Issue:3

    Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Amygdala; Animals; Caffeine; Differential Threshold; Kindling, Neurologic; Male; Papaverine; Rats; Rats, Inbred Strains; Seizures

1984
Chronic caffeine consumption potentiates the hypotensive action of circulating adenosine.
    Life sciences, 1983, Mar-07, Volume: 32, Issue:10

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Drug Synergism; Male; Rats; Rats, Inbred Strains

1983
2'-Deoxyadenosine functionally uncouples adenylate cyclase from the guanyl nucleotide subunit without altering simultaneous GppNHp occupancy.
    FEBS letters, 1980, Jul-28, Volume: 116, Issue:2

    Topics: Adenosine; Adenylyl Cyclases; Animals; Caffeine; Cell Line; Cell Membrane; Deoxyadenosines; Enzyme Activation; Glioma; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Macromolecular Substances; Mice; Neuroblastoma

1980
Stimulation of nucleologenesis by adenosine.
    Cell biology international reports, 1982, Volume: 6, Issue:1

    Topics: Adenosine; Caffeine; Cell Division; Cell Nucleolus; Cell Nucleus; Chromatin; Densitometry; Plant Cells

1982
ATP level and caffeine efficiency on cytokinesis inhibition in plants.
    European journal of cell biology, 1982, Volume: 27, Issue:2

    Topics: 2,4-Dinitrophenol; Adenosine; Adenosine Triphosphate; Caffeine; Cell Division; Dinitrophenols; Fluoroacetates; Nucleosides; Oxygen; Plant Cells; Plants

1982
N6 (L-phenylisopropyl) adenosine (L-PHA) increases slow-wave sleep (S2) and decreases wakefulness in rats.
    Brain research, 1982, Aug-19, Volume: 246, Issue:1

    Topics: Adenosine; Animals; Caffeine; Male; Phenylisopropyladenosine; Rats; Sleep; Wakefulness

1982
Effect of caffeine on G2 repair and its reversion by adenosine.
    Mutation research, 1982, Volume: 106, Issue:2

    Topics: Adenosine; Adenosine Triphosphate; Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; DNA Repair; Plants; Radiation-Sensitizing Agents; Uracil; Xanthines

1982
Effects of morphine and caffeine on adenosine release from rat cerebral cortex: is caffeine a morphine antagonist.
    Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:12

    Topics: Acetylcholine; Adenosine; Animals; Caffeine; Cerebral Cortex; Male; Morphine; Rats; Tritium

1980
Adenosine discriminates between the caffeine and adenine nucleotide sites on the sheep cardiac sarcoplasmic reticulum calcium-release channel.
    The Journal of membrane biology, 1994, Volume: 137, Issue:2

    Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Ion Channel Gating; Magnesium; Myocardium; Ruthenium Red; Ryanodine; Sarcoplasmic Reticulum; Sheep

1994
Vascular effects of pentoxifylline in humans.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:4

    Topics: Adenosine; Adult; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Female; Forearm; Hemodynamics; Humans; Infusions, Intra-Arterial; Male; Muscle, Smooth, Vascular; Pentoxifylline; Receptors, Purinergic P1; Vasodilation

1994
Quantification of the in vivo potency of the adenosine A2 receptor antagonist 8-(3-chlorostyryl)caffeine.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Adenosine; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Drug Evaluation, Preclinical; Drug Interactions; Heart Rate; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats

1995
Spinal opioid receptors and adenosine release: neurochemical and behavioral characterization of opioid subtypes.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Adenosine; Analgesics; Animals; Behavior, Animal; Caffeine; Calcium; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Nociceptors; Oligopeptides; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Synaptosomes

1995
Hemocyte adhesion in the California mussel (Mytilus californianus): regulation by adenosine.
    Biochimica et biophysica acta, 1995, Aug-31, Volume: 1268, Issue:2

    Topics: Adenosine; Animals; Bivalvia; Caffeine; Cell Adhesion; Cyclic AMP; Hemocytes; Receptors, Purinergic P1

1995
Locomotor activity in mice during chronic treatment with caffeine and withdrawal.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Caffeine; Dopamine Agents; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Parasympathomimetics; Substance Withdrawal Syndrome; Xanthines

1993
Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Corpus Striatum; Enkephalins; Gene Expression Regulation; Globus Pallidus; Neurons; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Purinergic; Substance P; Substantia Nigra

1993
G2 repair and aging: influence of donor age on chromosomal aberrations in human lymphocytes.
    Mutation research, 1993, Volume: 295, Issue:2

    Topics: Adenosine; Adult; Aged; Aging; Caffeine; Cell Cycle; Child, Preschool; Chromosome Aberrations; DNA Repair; Female; Humans; In Vitro Techniques; Infant; Male; Middle Aged; Niacinamide

1993
[Quantitative and qualitative criteria for assessing the efficacy of antimutagens in an experiment].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1993, Issue:3

    Topics: 4-Aminobenzoic Acid; Adenosine; alpha-Tocopherol; Animals; Antimutagenic Agents; Benzoates; Bone Marrow; Bone Marrow Cells; Caffeine; Chromosome Aberrations; Dose-Response Relationship, Drug; Drug Combinations; Gamma Rays; Humans; Lymphocytes; Magnoliopsida; Mice; Salmonella typhimurium; Seeds; Tocopherols; Vitamin E

1993
Effects of xanthine derivatives in a light/dark test in mice and the contribution of adenosine receptors.
    Methods and findings in experimental and clinical pharmacology, 1994, Volume: 16, Issue:9

    Topics: Adenosine; Animals; Antihypertensive Agents; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Interactions; Light; Male; Mice; Phenethylamines; Purinergic P1 Receptor Antagonists; Structure-Activity Relationship; Theophylline; Xanthines

1994
[Mutagenesis, antimutagenesis and the cellular regulatory system].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1995, Issue:1

    Topics: Adenosine; Antimutagenic Agents; Caffeine; Colchicine; Cyclic AMP; Mutagenesis; Plant Cells; Plants; Seeds; Theophylline

1995
Partial sciatic nerve ligation results in an enlargement of the receptive field and enhancement of the response of dorsal horn neurons to noxious stimulation by an adenosine agonist.
    Pain, 1994, Volume: 58, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Caffeine; Causalgia; Electrophysiology; Hyperalgesia; Male; Neurons; Nociceptors; Pain Measurement; Patch-Clamp Techniques; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Stimulation, Chemical; Vasodilator Agents

1994
Effects of neonatal exposure to caffeine on adenosine A1 receptor ontogeny using autoradiography.
    Brain research. Developmental brain research, 1994, Oct-14, Volume: 82, Issue:1-2

    Topics: Adenosine; Administration, Oral; Aging; Animals; Animals, Newborn; Autoradiography; Brain; Caffeine; Cerebellum; Female; Hippocampus; Humans; Infant, Newborn; Infant, Premature; Male; Neurons; Organ Specificity; Pyramidal Cells; Rats; Receptors, Purinergic P1; Thalamus; Tritium

1994
Effects of alkylxanthines on contractility of diaphragm fibres isolated from normal and sensitized guinea-pigs.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:12

    Topics: Adenosine; Animals; Bronchodilator Agents; Caffeine; Calcium; Culture Media; Dantrolene; Diaphragm; Electric Stimulation; Extracellular Space; Female; Guinea Pigs; Immunization; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Serum Albumin, Bovine; Theobromine; Theophylline; Verapamil; Xanthines

1993
Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors.
    Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Brain Chemistry; Caffeine; CHO Cells; Cricetinae; Gene Expression; Iodine Radioisotopes; Molecular Structure; Phenethylamines; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines

1994
Chronic effects of ethanol on central adenosine function of mice.
    Brain research, 1994, Jul-04, Volume: 650, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Caffeine; Ethanol; Male; Mice; Motor Activity; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Time Factors

1994
Caffeine and propranolol block the increase in rat pineal melatonin production produced by stimulation of adenosine receptors.
    Neuroscience letters, 1994, Jul-18, Volume: 176, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Binding, Competitive; Caffeine; Caudate Nucleus; Circadian Rhythm; Male; Melatonin; Pineal Gland; Propranolol; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Vasodilator Agents

1994
Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3

    Topics: Adenosine; Animals; Caffeine; Corpus Striatum; Dopamine; Male; Methamphetamine; Mice; MPTP Poisoning; Receptors, Purinergic P1; Theophylline; Tyrosine 3-Monooxygenase

1994
Epileptogenic actions of xanthines in relation to their affinities for adenosine A1 receptors in CA3 neurons of hippocampal slices (guinea pig).
    Brain research, 1994, Mar-21, Volume: 640, Issue:1-2

    Topics: Adenosine; Animals; Caffeine; Calcium; Cyclic AMP; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Xanthines

1994
Calcium concentration changes in the calyciform nerve terminal of the avian ciliary ganglion after tetanic stimulation.
    Journal of the autonomic nervous system, 1994, Volume: 46, Issue:3

    Topics: Adenosine; Animals; Caffeine; Calcium; Chick Embryo; Electric Stimulation; Ganglia, Parasympathetic; Long-Term Potentiation; Nerve Endings; Nifedipine; Potassium; Terpenes; Tetany; Thapsigargin

1994
Reduction by intracellular calcium chelation of acetylcholine secretion without occluding the effects of adenosine at frog motor nerve endings.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Acetylcholine; Adenosine; Animals; Buffers; Caffeine; Calcium; Chelating Agents; Cytoplasm; Drug Interactions; Egtazic Acid; In Vitro Techniques; Intracellular Fluid; Motor Neurons; Nerve Endings; Neuromuscular Junction; Rana pipiens

1994
Effects of adenosine receptor agonists and antagonists on acquisition of passive avoidance learning.
    European journal of pharmacology, 1994, May-02, Volume: 256, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Avoidance Learning; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilator Agents

1994
Behavioral and pharmacological modulation of respiration in rhesus monkeys.
    Journal of the experimental analysis of behavior, 1994, Volume: 62, Issue:1

    Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Cocaine; Humans; Infant, Newborn; Macaca mulatta; Male; Plethysmography; Respiration

1994
Serum caffeine levels after 24 hours of caffeine abstention: observations on clinical patients undergoing myocardial perfusion imaging with dipyridamole or adenosine.
    European journal of nuclear medicine, 1994, Volume: 21, Issue:1

    Topics: Adenosine; Caffeine; Contraindications; Coronary Disease; Dipyridamole; Heart; Hemodynamics; Humans; Immunoenzyme Techniques; Male; Middle Aged; Thallium Radioisotopes; Time Factors; Tomography, Emission-Computed, Single-Photon

1994
Adenosine agonists reduce conditioned avoidance responding in the rat.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:4

    Topics: Adenosine; Animals; Antipsychotic Agents; Avoidance Learning; Binding, Competitive; Caffeine; Catalepsy; Dose-Response Relationship, Drug; Electroshock; Female; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, Purinergic; Receptors, Purinergic P1

1993
Role of adenosine in the hypoxic ventilatory response of the newborn piglet.
    Pediatric pulmonology, 1994, Volume: 17, Issue:1

    Topics: Adenosine; Animals; Animals, Newborn; Caffeine; Cerebrospinal Fluid; Citrates; Dipyridamole; Drug Combinations; Hypoxia; Oxygen; Purinergic P1 Receptor Antagonists; Respiration; Swine; Theophylline

1994
ATP-evoked increases in intracellular calcium in neurons and glia from the dorsal spinal cord.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:3 Pt 2

    Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Caffeine; Calcium; Electrophysiology; Extracellular Space; Intracellular Membranes; Neuroglia; Neurons; Rats; Rats, Wistar; Spinal Cord; Suramin; Terpenes; Thapsigargin

1994
Defective G2 repair in Down syndrome: effect of caffeine, adenosine and niacinamide in control and X-ray irradiated lymphocytes.
    Clinical genetics, 1994, Volume: 45, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Caffeine; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; DNA Repair; Down Syndrome; Humans; Infant; Lymphocytes; Niacinamide

1994
Mechanisms of CBF augmentation during hypoxia in cats: probable participation of prostacyclin, nitric oxide and adenosine.
    The Keio journal of medicine, 1994, Volume: 43, Issue:1

    Topics: Adenosine; Animals; Arginine; Caffeine; Cats; Cerebrovascular Circulation; Epoprostenol; Hypoxia; Indomethacin; Nitric Oxide; omega-N-Methylarginine

1994
Restraint stress potentiates analgesia induced by 5'-N-ethylcarboxamidoadenosine: comparison with morphine.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesia; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Restraint, Physical; Stress, Physiological

1993
Effect of adenosine blockade on plasma renin activity and catecholamines.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1993, Volume: 17, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Consciousness; Epinephrine; Hydralazine; Kidney; Male; Norepinephrine; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renin; Renin-Angiotensin System; Secretory Rate; Sodium, Dietary; Theophylline; Xanthines

1993
Caffeine withdrawal: apparent heterologous sensitization to adenosine and prostacyclin actions in human platelets.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Alprostadil; Blood Platelets; Caffeine; Epoprostenol; Humans; Male; Models, Biological; Purinergic P1 Receptor Antagonists; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Purinergic P1; Sensitivity and Specificity; Substance Withdrawal Syndrome; Up-Regulation

1993
Adenosine release is a major cause of failure of synaptic transmission during hypoglycaemia in rat hippocampal slices.
    Neuroscience letters, 1993, Jun-11, Volume: 155, Issue:2

    Topics: Action Potentials; Adenosine; Animals; Caffeine; Cell Hypoxia; Energy Metabolism; Evoked Potentials; Glucose; Glyburide; Hippocampus; Hypoglycemia; Neural Inhibition; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline; Tolbutamide

1993
8-(3-Chlorostyryl)caffeine (CSC) is a selective A2-adenosine antagonist in vitro and in vivo.
    FEBS letters, 1993, May-24, Volume: 323, Issue:1-2

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Caffeine; Locomotion; Male; Mice; Rats

1993
Effects of adenosine agonists on ventilation during hypercapnia, hypoxia and hyperoxia in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Carbon Dioxide; Female; Hypercapnia; Hypoxia; Macaca mulatta; Male; Oxygen; Phenethylamines; Plethysmography; Pyrrolidinones; Receptors, Purinergic; Respiration; Respiratory Function Tests; Rolipram

1993
Effect of long term caffeine treatment on A1 and A2 adenosine receptor binding and on mRNA levels in rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:4

    Topics: Adenosine; Animals; Autoradiography; Base Sequence; Blotting, Northern; Brain; Caffeine; Corpus Striatum; Hippocampus; In Situ Hybridization; Male; Molecular Sequence Data; Organ Specificity; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; RNA, Messenger; Xanthines

1993
Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway.
    Neuroscience, 1995, Volume: 68, Issue:3

    Topics: Adenosine; Adrenergic Uptake Inhibitors; Animals; Caffeine; Dopamine Agonists; Ergolines; Genes, fos; Globus Pallidus; Immunohistochemistry; Male; Neostriatum; Neural Pathways; Phosphodiesterase Inhibitors; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine; Theobromine; Theophylline

1995
Effects of diazepam and cyclohexyladenosine on open-field behavior in rats perinatally exposed to caffeine.
    Life sciences, 1996, Volume: 58, Issue:8

    Topics: Adenosine; Animals; Caffeine; Diazepam; Eliminative Behavior, Animal; Emotions; Female; Grooming; Locomotion; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Sex Characteristics

1996
Antinociception by adenosine analogs and an adenosine kinase inhibitor: dependence on formalin concentration.
    European journal of pharmacology, 1995, Nov-14, Volume: 286, Issue:2

    Topics: Adenosine; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Caffeine; Deoxyadenosines; Enzyme Inhibitors; Formaldehyde; Male; Pentostatin; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1

1995
Adenosine A2b receptors mediate an increase in interleukin (IL)-6 mRNA and IL-6 protein synthesis in human astroglioma cells.
    Journal of neurochemistry, 1996, Volume: 66, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antineoplastic Agents; Astrocytoma; Blotting, Northern; Caffeine; Dose-Response Relationship, Immunologic; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; RNA, Messenger; Stereoisomerism; Tumor Cells, Cultured; Xanthines

1996
Purine suppression of proliferation of Sertoli-like TM4 cells in culture.
    Cell proliferation, 1995, Volume: 28, Issue:12

    Topics: Adenosine; Animals; Caffeine; Cell Division; Cells, Cultured; Male; Mice; Purinergic P1 Receptor Antagonists; Purines; Receptors, Purinergic P1; Sertoli Cells; Theobromine; Theophylline

1995
Anxiolytic activity of adenosine receptor activation in mice.
    British journal of pharmacology, 1995, Volume: 116, Issue:3

    Topics: Adenosine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Male; Maze Learning; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline

1995
Circadian rhythm in the Ca(2+)-inhibitable adenylyl activity of the rat striatum.
    FEBS letters, 1996, May-06, Volume: 385, Issue:3

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Caffeine; Calcium; Circadian Rhythm; Colforsin; Corpus Striatum; Cyclic AMP; Guanosine Diphosphate; Isoenzymes; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley

1996
Methylxanthines with adenosine alter TNF alpha-primed PMN activation.
    Immunopharmacology, 1995, Volume: 31, Issue:1

    Topics: Adenosine; Caffeine; Humans; Kinetics; Luminescent Measurements; Neutrophil Activation; Neutrophils; Pentoxifylline; Peroxidase; Superoxides; Tumor Necrosis Factor-alpha

1995
Caffeine-evoked contractures in single slow (tonic) muscle fibres of the frog (Rana temporaria and R. esculenta).
    Pflugers Archiv : European journal of physiology, 1996, Volume: 432, Issue:2

    Topics: Adenosine; Administration, Topical; Animals; Caffeine; Cations, Divalent; Dose-Response Relationship, Drug; Gallopamil; Hydrogen-Ion Concentration; Injections; Lanthanum; Muscle Contraction; Muscle Fibers, Skeletal; Osmolar Concentration; Potassium; Rana esculenta; Rana temporaria; Time Factors

1996
Effects of N6-cyclopentyladenosine and caffeine on sleep regulation in the rat.
    European journal of pharmacology, 1996, Apr-11, Volume: 300, Issue:3

    Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Electroencephalography; Male; Rats; Rats, Sprague-Dawley; Sleep; Sleep Deprivation; Sleep Stages

1996
An adenosine agonist increases blood flow and density of capillary branches in the optic tectum of Xenopus laevis tadpoles.
    Microcirculation (New York, N.Y. : 1994), 1994, Volume: 1, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Capillaries; Microcirculation; Microscopy, Video; Neovascularization, Physiologic; Nitroglycerin; Regional Blood Flow; Superior Colliculi; Theophylline; Time Factors; Vasodilator Agents; Xenopus laevis

1994
Genetic variation in immediate and delayed postictal refractory period in rats.
    Brain research, 1996, May-20, Volume: 721, Issue:1-2

    Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Epilepsy; Genetic Variation; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Species Specificity

1996
Adenosine A1 and A2 receptors modulate extracellular dopamine levels in rat striatum.
    Neuroscience letters, 1996, Jul-05, Volume: 212, Issue:1

    Topics: Adenosine; Animals; Antihypertensive Agents; Caffeine; Camptothecin; Dopamine; Enzyme Inhibitors; Extracellular Space; Irinotecan; Male; Microdialysis; Neostriatum; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theobromine; Vasodilator Agents

1996
Central effects of caffeine on renal renin secretion and norepinephrine spillover.
    Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:2

    Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Hydralazine; Injections, Intraventricular; Kidney; Male; Norepinephrine; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin; Vasodilator Agents; Xanthines

1996
Adenosine A1 receptor-dopamine D1 receptor interaction in the rat limbic system: modulation of dopamine D1 receptor antagonist binding sites.
    Neuroscience letters, 1996, Apr-19, Volume: 208, Issue:2

    Topics: Adenosine; Animals; Autoradiography; Benzazepines; Binding Sites; Binding, Competitive; Caffeine; Central Nervous System Stimulants; Dopamine Antagonists; Iodine Radioisotopes; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1

1996
Cerebral ischemia in gerbils: effects of acute and chronic treatment with adenosine A2A receptor agonist and antagonist.
    European journal of pharmacology, 1995, Dec-20, Volume: 287, Issue:3

    Topics: Adenosine; Animals; Brain Ischemia; Caffeine; Cell Survival; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models, Animal; Female; Gerbillinae; Hippocampus; Laser-Doppler Flowmetry; Neurons; Phenethylamines; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Treatment Outcome

1995
Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis.
    Scandinavian journal of immunology, 1997, Volume: 45, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Caffeine; Dipyridamole; Humans; Inosine; Leukocytes, Mononuclear; Lipopolysaccharides; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Rolipram; Tumor Necrosis Factor-alpha; Xanthines

1997
Determination of the effects of caffeine and carbamazepine on striatal dopamine release by in vivo microdialysis.
    European journal of pharmacology, 1997, Feb-26, Volume: 321, Issue:2

    Topics: Adenosine; Animals; Anticonvulsants; Caffeine; Carbamazepine; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Ligands; Male; Microdialysis; Rats; Rats, Wistar; Receptors, Purinergic P1

1997
Caffeine: a model drug of abuse.
    NIDA research monograph, 1996, Volume: 162

    Topics: Adenosine; Animals; Behavior; Caffeine; Dopamine; Humans; Substance-Related Disorders

1996
Endogenous adenosine mediates the presynaptic inhibition induced by aglycemia at corticostriatal synapses.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jun-15, Volume: 17, Issue:12

    Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Corpus Striatum; Evoked Potentials; Glipizide; Glucose; Glutamic Acid; Hypoglycemic Agents; In Vitro Techniques; Membrane Potentials; Neurons; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synapses; Theophylline; Tolbutamide; Xanthines

1997
Adenosine exerts a glycogen-sparing action in contracting rat skeletal muscle.
    The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 1

    Topics: Adenosine; Animals; Caffeine; Cyclic AMP; Drug Combinations; Glycogen; Glycogen Synthase; Male; Muscle Contraction; Muscle, Skeletal; Phosphorylase a; Rats; Rats, Wistar; Theobromine; Xanthines

1997
A1 and A2A adenosine receptors and A1 mRNA in mouse brain: effect of long-term caffeine treatment.
    Brain research, 1997, Jul-11, Volume: 762, Issue:1-2

    Topics: Adenosine; Animals; Antihypertensive Agents; Autoradiography; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; In Situ Hybridization; Male; Mice; Mice, Inbred Strains; Phenethylamines; Radioligand Assay; Receptors, Purinergic P1; RNA, Messenger; Time Factors; Tritium; Xanthines

1997
Adenosine receptors. Knockouts anxious for new therapy.
    Nature, 1997, Aug-14, Volume: 388, Issue:6643

    Topics: Adenosine; Animals; Caffeine; Drug Therapy; Mice; Mice, Knockout; Pain; Receptors, Purinergic P1

1997
Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor.
    Nature, 1997, Aug-14, Volume: 388, Issue:6643

    Topics: Adenosine; Aggression; Animals; Blood Pressure; Brain; Caffeine; Cloning, Molecular; Heart Rate; Humans; Hypertension; Male; Mice; Mice, Knockout; Molecular Sequence Data; Pain; Phenethylamines; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Restriction Mapping; Sequence Homology, Amino Acid

1997
Activation of phosphodiesterase IV during desensitization of the A2A adenosine receptor-mediated cyclic AMP response in rat pheochromocytoma (PC12) cells.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adrenal Gland Neoplasms; Animals; Blotting, Western; Caffeine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Activation; Enzyme Inhibitors; Isoquinolines; Kinetics; PC12 Cells; Phenethylamines; Pheochromocytoma; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Recombinant Proteins; Sulfonamides

1997
Caffeine alters plasma adenosine levels.
    Nature, 1997, Sep-11, Volume: 389, Issue:6647

    Topics: Adenosine; Animals; Caffeine; Humans; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Sympathomimetics; Tyramine

1997
Purinergic modulation of rat urinary bladder detrusor smooth muscle.
    General pharmacology, 1997, Volume: 29, Issue:4

    Topics: Adenosine; Adenosine Triphosphate; Animals; Atropine; Caffeine; Electric Stimulation; In Vitro Techniques; Labetalol; Male; Muscle, Smooth; Purinergic Agonists; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Quinidine; Rats; Rats, Wistar; Receptors, Purinergic; Urinary Bladder

1997
Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonists.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Adenosine; Animals; Binding, Competitive; Brain; Caffeine; Molecular Structure; Phenethylamines; Protein Binding; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theobromine; Xanthines

1997
Adenosine A2A receptors facilitate 45Ca2+ uptake through class A calcium channels in rat hippocampal CA3 but not CA1 synaptosomes.
    Neuroscience letters, 1997, Nov-28, Volume: 238, Issue:1-2

    Topics: 2-Chloroadenosine; Adenosine; Animals; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Hippocampus; Male; omega-Agatoxin IVA; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Spider Venoms; Synaptosomes; Veratridine; Xanthines

1997
Adenosine-stimulated intracellular calcium increase in cultured human uterine myocyte.
    Gynecologic and obstetric investigation, 1998, Volume: 45, Issue:1

    Topics: Adenosine; Adult; Aniline Compounds; Caffeine; Calcium; Cells, Cultured; Female; Fluorescent Dyes; Humans; Middle Aged; Myometrium; Xanthenes

1998
Evidence for physiologically active axonal adenosine receptors in the rat corpus callosum.
    Brain research, 1998, Feb-16, Volume: 784, Issue:1-2

    Topics: Action Potentials; Adenosine; Animals; Axons; Caffeine; Corpus Callosum; Electrophysiology; Immunohistochemistry; Male; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Synaptic Transmission

1998
Stress-dependent antinociceptive effects of carbamazepine: a study in stressed and nonstressed rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:1

    Topics: Adenosine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Caffeine; Carbamazepine; Cerebral Ventricles; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Male; Naloxone; Pain; Physical Stimulation; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Time Factors

1998
Inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats.
    Behavioral neuroscience, 1998, Volume: 112, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Analysis of Variance; Animals; Caffeine; Central Nervous System Stimulants; Electroshock; Enzyme Inhibitors; Escape Reaction; Fear; Helplessness, Learned; Male; Neural Inhibition; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Restraint, Physical; Stress, Psychological

1998
Caffeine abstinence augments the systolic blood pressure response to adenosine in humans.
    The American journal of cardiology, 1998, Jun-01, Volume: 81, Issue:11

    Topics: Adenosine; Adult; Blood Pressure; Caffeine; Heart Rate; Humans; Male; Middle Aged; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome

1998
The role of adenosine in rat coronary flow regulation during respiratory and metabolic acidosis.
    European journal of pharmacology, 1998, Sep-04, Volume: 356, Issue:2-3

    Topics: Acidosis; Acidosis, Respiratory; Adenosine; Animals; Caffeine; Coronary Circulation; Hypercapnia; Male; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Theophylline; Triazines; Triazoles

1998
Inhibition of strychnine-allodynia is mediated by spinal adenosine A1- but not A2-receptors in the rat.
    Brain research, 1998, Oct-12, Volume: 808, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Spinal; Male; Pain; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Cord; Strychnine; Xanthines

1998
Calcium in sympathetic boutons of rat superior cervical ganglion during facilitation, augmentation and potentiation.
    Journal of the autonomic nervous system, 1998, Aug-27, Volume: 73, Issue:1

    Topics: Action Potentials; Adenosine; Adrenergic Fibers; Agatoxins; Animals; Caffeine; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Central Nervous System Stimulants; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Ionophores; Kinetics; Nifedipine; omega-Conotoxin GVIA; Peptides; Presynaptic Terminals; Rats; Rats, Wistar; Ryanodine; Spider Venoms; Superior Cervical Ganglion; Synaptic Transmission; Thapsigargin

1998
Quantifying the molecular structure of behavior: separate effects of caffeine, cocaine, and adenosine agonists on interresponse times and lever-press durations.
    Behavioural pharmacology, 1997, Volume: 8, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Phenylisopropyladenosine; Rats; Reaction Time; Reinforcement Schedule; Time Factors; Vasodilator Agents

1997
Behavioral characterization of caffeine and adenosine agonists during chronic caffeine exposure.
    Behavioural pharmacology, 1997, Volume: 8, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Phenylisopropyladenosine; Rats

1997
Adenosine A2A receptors inhibit the conductance of NMDA receptor channels in rat neostriatal neurons.
    Amino acids, 1998, Volume: 14, Issue:1-3

    Topics: Adenosine; Adenylyl Cyclases; Animals; Caffeine; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; In Vitro Techniques; Neostriatum; Neurons; Patch-Clamp Techniques; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Signal Transduction; Theophylline

1998
Pharmacological interactions between magnesium ion and adenosine on monoaminergic system in the central nervous system.
    Magnesium research, 1998, Volume: 11, Issue:4

    Topics: Adenosine; Animals; Biogenic Monoamines; Caffeine; Carbamazepine; Central Nervous System; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Magnesium; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Serotonin; Theobromine; Theophylline; Visual Cortex

1998
Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin.
    The European journal of neuroscience, 1999, Volume: 11, Issue:1

    Topics: Adenosine; Animals; Antihypertensive Agents; Biological Transport; Caffeine; Central Nervous System Stimulants; Fluoxetine; Hippocampus; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quipazine; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Theobromine; Theophylline; Vasodilator Agents

1999
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines

1999
Molecular and behavioral effects mediated by Gs-coupled adenosine A2a, but not serotonin 5-Ht4 or 5-Ht6 receptors following antipsychotic administration.
    Neuroscience, 1999, Volume: 89, Issue:3

    Topics: Adenosine; Animals; Antipsychotic Agents; Behavior, Animal; Caffeine; Catalepsy; Clozapine; Corpus Striatum; Cyclic AMP; Dopamine D2 Receptor Antagonists; Gene Expression Regulation; Genes, fos; GTP-Binding Protein alpha Subunits, Gs; Haloperidol; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D2; Receptors, Purinergic P1; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Second Messenger Systems; Serotonin; Serotonin Antagonists; Theophylline

1999
Peripheral antinociceptive action of amitriptyline in the rat formalin test: involvement of adenosine.
    Pain, 1999, Volume: 80, Issue:1-2

    Topics: Adenosine; Amitriptyline; Analgesics; Animals; Antidepressive Agents, Tricyclic; Caffeine; Dose-Response Relationship, Drug; Male; Pain; Pain Measurement; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Glutamate; Receptors, Histamine; Receptors, Opioid

1999
Adenosine receptor antagonists inhibit the development of morphine sensitization in the C57BL/6 mouse.
    Neuroscience letters, 1999, Apr-02, Volume: 264, Issue:1-3

    Topics: Adenosine; Animals; Caffeine; Drug Combinations; Drug Resistance; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Narcotics; Purinergic P1 Receptor Antagonists; Xanthines

1999
Adenine-nucleotide binding sites on the inositol 1,4,5-trisphosphate receptor bind caffeine, but not adenophostin A or cyclic ADP-ribose.
    Cell calcium, 1999, Volume: 25, Issue:2

    Topics: Adenine; Adenosine; Adenosine Diphosphate Ribose; Animals; Binding Sites; Caffeine; Calcium; Calcium Channels; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Inositol 1,4,5-Trisphosphate Receptors; Mice; Models, Genetic; Protein Binding; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Time Factors

1999
Intravascular source of adenosine during forearm ischemia in humans: implications for reactive hyperemia.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:6

    Topics: Adenosine; Adult; Caffeine; Female; Forearm; Humans; Hyperemia; Ischemia; Male; Microdialysis; Muscle, Skeletal; Reference Values; Regional Blood Flow; Substance Withdrawal Syndrome; Thromboxanes; Time Factors

1999
Adenosine upregulates VEGF expression in cultured myocardial vascular smooth muscle cells.
    The American journal of physiology, 1999, Volume: 277, Issue:2

    Topics: Adenosine; Animals; Caffeine; Cell Hypoxia; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Endothelial Growth Factors; Lymphokines; Male; Muscle, Smooth, Vascular; Myocardium; Reference Values; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1999
Caffeine-mediated induction of c-fos, zif-268 and arc expression through A1 receptors in the striatum: different interactions with the dopaminergic system.
    The European journal of neuroscience, 1999, Volume: 11, Issue:9

    Topics: Adenosine; Animals; Apoptosis Regulatory Proteins; Caffeine; Cell Count; Central Nervous System Stimulants; DNA-Binding Proteins; Dopamine; Early Growth Response Protein 1; Fluorescent Antibody Technique; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Hydroxydopamines; Image Processing, Computer-Assisted; Immediate-Early Proteins; Immunohistochemistry; In Situ Hybridization; Male; Muscle Proteins; Neostriatum; Neurons; Rats; Rats, Wistar; Receptors, Purinergic P1; Transcription Factors

1999
Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors.
    European journal of pharmacology, 1999, Sep-10, Volume: 380, Issue:2-3

    Topics: Adenosine; Animals; Autoradiography; Binding, Competitive; Brain; Caffeine; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrazines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Tritium; Xanthines

1999
Anticonvulsant action of 2-chloroadenosine injected focally into the perirhinal cortex in amygdaloid kindled rats.
    Epilepsy research, 1999, Volume: 37, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Amygdala; Analysis of Variance; Animals; Anticonvulsants; Caffeine; Dose-Response Relationship, Drug; Injections; Kindling, Neurologic; Male; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures

1999
Adenosine and memory storage: effect of A(1) and A(2) receptor antagonists.
    Psychopharmacology, 1999, Volume: 146, Issue:2

    Topics: Adenosine; Animals; Avoidance Learning; Caffeine; Central Nervous System Stimulants; Male; Memory; Mice; Purinergic P1 Receptor Antagonists; Pyrimidines; Triazoles; Xanthines

1999
Adenosine inhibits depolarization-induced Ca(2+) release in mammalian skeletal muscle.
    Muscle & nerve, 1999, Volume: 22, Issue:12

    Topics: Adenosine; Adenosine Monophosphate; Animals; Caffeine; Calcium; In Vitro Techniques; Inosine Monophosphate; Magnesium; Muscle Contraction; Muscle Fatigue; Muscle Fibers, Skeletal; Muscle, Skeletal; Rats; Rats, Long-Evans; Sarcoplasmic Reticulum

1999
Actions of adenosine A2A receptor antagonist KW-6002 on drug-induced catalepsy and hypokinesia caused by reserpine or MPTP.
    Psychopharmacology, 1999, Volume: 147, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine; Animals; Antiparkinson Agents; Antipsychotic Agents; Caffeine; Catalepsy; Dopamine Agents; Hypokinesia; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Reserpine; Theophylline

1999
Role of adenosine A2 receptors in brain stimulation reward under baseline conditions and during cocaine withdrawal in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Dec-15, Volume: 19, Issue:24

    Topics: Adenosine; Animals; Brain; Caffeine; Cocaine; Differential Threshold; Dopamine Uptake Inhibitors; Drug Interactions; Electric Stimulation; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Reaction Time; Receptors, Purinergic P1; Reference Values; Reward; Substance Withdrawal Syndrome; Theobromine

1999
Both fertilization promoting peptide and adenosine stimulate capacitation but inhibit spontaneous acrosome loss in ejaculated boar spermatozoa in vitro.
    Molecular reproduction and development, 2000, Volume: 55, Issue:1

    Topics: Acrosome; Adenosine; Animals; Caffeine; Cells, Cultured; Chlortetracycline; Dose-Response Relationship, Drug; Humans; Male; Mice; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Spermatozoa; Swine; Thyrotropin-Releasing Hormone

2000
Ligand-activation of the adenosine A2a receptors inhibits IL-12 production by human monocytes.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Jan-01, Volume: 164, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Caffeine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Immunologic; Female; Humans; Immunosuppressive Agents; Interleukin-10; Interleukin-12; Ligands; Lipopolysaccharides; Male; Monocytes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Signal Transduction

2000
Acute paw oedema induced by local injection of adenosine A(1), A(2) and A(3) receptor agonists.
    European journal of pharmacology, 1999, Dec-15, Volume: 386, Issue:2-3

    Topics: Acute Disease; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Drug Interactions; Edema; Enzyme Inhibitors; Histamine H1 Antagonists; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3

1999
Adenosine receptor occupancy suppresses chemoattractant-induced phospholipase D activity by diminishing membrane recruitment of small GTPases.
    Blood, 2000, Jan-15, Volume: 95, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); ADP-Ribosylation Factor 1; Adult; Caffeine; Cell Membrane; Enzyme Activation; GTP Phosphohydrolases; Humans; In Vitro Techniques; Isoenzymes; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenethylamines; Phospholipase D; Protein Kinase C; Protein Kinase C-alpha; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; rhoA GTP-Binding Protein; Triazoles

2000
The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists.
    Psychopharmacology, 2000, Volume: 148, Issue:2

    Topics: Adenosine; Administration, Oral; Animals; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Administration Schedule; Injections, Intraperitoneal; Light; Male; Maze Learning; Mice; Mice, Knockout; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Reaction Time; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines

2000
Activation of adenosine A1 receptors facilitates the analgesic effect of ketorolac and ketorolac-caffeine combinations in the rat.
    Proceedings of the Western Pharmacology Society, 1999, Volume: 42

    Topics: Adenosine; Analgesics, Non-Narcotic; Animals; Area Under Curve; Caffeine; Central Nervous System Stimulants; Drug Synergism; Female; Ketorolac; Pain Measurement; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar

1999
Involvement of ryanodine receptors in EPYLRFamide-mediated reduction of acetylcholine-induced inward currents in helix lucorum identified neurones.
    Regulatory peptides, 2000, Mar-17, Volume: 88, Issue:1-3

    Topics: Acetylcholine; Adenosine; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Aniline Compounds; Animals; Caffeine; Chelating Agents; Cyclic ADP-Ribose; Dantrolene; Egtazic Acid; Fluorescent Dyes; Helix, Snails; Neurons; Neuropeptides; Ryanodine; Ryanodine Receptor Calcium Release Channel; Xanthenes

2000
Promotion of forskolin-induced long-term potentiation of synaptic transmission by caffeine in area CA1 of the rat hippocampus.
    The Chinese journal of physiology, 1999, Dec-31, Volume: 42, Issue:4

    Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Colforsin; Cyclic AMP; Drug Synergism; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Quinazolines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazoles; Xanthines

1999
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence.
    Life sciences, 2000, Volume: 66, Issue:10

    Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Theobromine; Theophylline

2000
Inhibition of synaptically evoked cortical acetylcholine release by adenosine: an in vivo microdialysis study in the rat.
    Neuroscience, 2000, Volume: 97, Issue:2

    Topics: Acetylcholine; Adenosine; Analysis of Variance; Animals; Caffeine; Cerebral Cortex; Chromatography, High Pressure Liquid; Dipyridamole; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synapses; Xanthines

2000
The adenosine receptor agonist, APNEA, increases calcium influx into rat cortical synaptosomes through N-type channels associated with A2a receptors.
    Neurochemical research, 2000, Volume: 25, Issue:4

    Topics: Adenosine; Animals; Brain Chemistry; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Cerebral Cortex; Dose-Response Relationship, Drug; Male; omega-Conotoxin GVIA; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptosomes; Xanthines

2000
Time for abstention from caffeine before an adenosine myocardial perfusion scan.
    Nuclear medicine communications, 2000, Volume: 21, Issue:4

    Topics: Adenosine; Adult; Aged; Caffeine; Drug Interactions; Exercise Test; False Negative Reactions; Heart; Humans; Middle Aged; Organophosphorus Compounds; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Time Factors

2000
Adenosine receptor expression and function in rat striatal cholinergic interneurons.
    British journal of pharmacology, 2000, Volume: 130, Issue:4

    Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Baclofen; Bicuculline; Caffeine; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; GABA Antagonists; Gene Expression; Male; Membrane Potentials; Naloxone; Narcotic Antagonists; Neurons; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Tritium; Xanthines

2000
Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain.
    Pediatric research, 2000, Volume: 48, Issue:2

    Topics: Adenosine; Animals; Animals, Newborn; Autoradiography; Brain; Caffeine; Female; Gene Expression Regulation, Developmental; In Situ Hybridization; Phenethylamines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Purinergic P1; Tritium; Xanthines

2000
Regulation of nociceptin mRNA expression in the septum by dopamine and adenosine systems.
    Neuroreport, 2000, Sep-28, Volume: 11, Issue:14

    Topics: Adenosine; Animals; Caffeine; Denervation; Dopamine; Dose-Response Relationship, Drug; Male; Mice; Mice, Knockout; Neural Pathways; Neurons; Nociceptin; Opioid Peptides; Oxidopamine; Receptor, Adenosine A2A; Receptors, Dopamine; Receptors, Purinergic P1; RNA, Messenger; Septal Nuclei; Stress, Physiological

2000
Adenosine preconditions against endothelin-induced constriction of coronary arterioles.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6

    Topics: Adenosine; Animals; Arterioles; Caffeine; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Microcirculation; Purinergic P1 Receptor Antagonists; Vasoconstriction; Vasodilation; Vasodilator Agents; Xanthines

2000
Caffeine increases paragigantocellularis neuronal firing rate and induces withdrawal signs in morphine-dependent rats.
    European journal of pharmacology, 2001, Feb-02, Volume: 412, Issue:3

    Topics: Adenosine; Analgesics, Opioid; Animals; Caffeine; Electrophysiology; Male; Medulla Oblongata; Microinjections; Morphine; Morphine Dependence; Neurons; Purinergic P1 Receptor Agonists; Rats; Substance Withdrawal Syndrome; Theophylline

2001
Adenosine induces initial hypoxic-ischemic depression of synaptic transmission in the rat hippocampus in vivo.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:3

    Topics: Acid-Base Equilibrium; Adenosine; Animals; Blood Pressure; Caffeine; Carotid Artery, Common; Constriction; Excitatory Postsynaptic Potentials; Heart Rate; Hippocampus; Hypoxia-Ischemia, Brain; Male; Oxygen; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline

2001
The role of the D(2) dopamine receptor (D(2)R) in A(2A) adenosine receptor (A(2A)R)-mediated behavioral and cellular responses as revealed by A(2A) and D(2) receptor knockout mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Feb-13, Volume: 98, Issue:4

    Topics: Adenosine; Amphetamines; Animals; Caffeine; Catalepsy; Corpus Striatum; Dopamine Antagonists; Enkephalins; Gene Expression; Haloperidol; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic P1; RNA, Messenger

2001
Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells.
    Biochemical pharmacology, 2001, Feb-15, Volume: 61, Issue:4

    Topics: Adenosine; Animals; Caffeine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theobromine; Theophylline; Transfection

2001
Regulation of in vitro penetration of frozen-thawed boar spermatozoa by caffeine and adenosine.
    Molecular reproduction and development, 2001, Volume: 58, Issue:4

    Topics: Acrosome Reaction; Adenosine; Animals; Caffeine; Coculture Techniques; Cryopreservation; Culture Media; Cyclic AMP; Female; Fertilization in Vitro; Male; Second Messenger Systems; Semen Preservation; Sperm Capacitation; Spermatozoa; Swine

2001
Antiadrenergic effects of adenosine in pressure overload hypertrophy.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:3

    Topics: Adenosine; Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; Caffeine; Calcium; Cardiomegaly; Cells, Cultured; Coronary Circulation; Disease Models, Animal; Echocardiography; In Vitro Techniques; Inosine; Isoproterenol; Male; Myocardial Contraction; Myocardium; Organ Size; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley

2001
Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jun-15, Volume: 21, Issue:12

    Topics: Adenosine; Amphetamine; Animals; Caffeine; Carrier Proteins; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Heterotrimeric GTP-Binding Proteins; Heterozygote; In Situ Hybridization; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Neurons; Organ Specificity; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D1; Receptors, Purinergic P1; RNA, Messenger

2001
Involvement of adenosine in the effect of antidepressants on glutamate and aspartate release in the rat prefrontal cortex.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:6

    Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Antidepressive Agents; Aspartic Acid; Brain; Caffeine; Glutamic Acid; Male; Microdialysis; Rats; Rats, Wistar; Veratridine

2001
A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle.
    FEBS letters, 2001, Jun-15, Volume: 499, Issue:1-2

    Topics: Adenosine; Adenosylhomocysteinase; Caffeine; Carbon Dioxide; Cell Extracts; Chloroplasts; Homocysteine; Hydrolases; Methionine Adenosyltransferase; Methylation; Plant Leaves; S-Adenosylhomocysteine; S-Adenosylmethionine; Tea; Theobromine

2001
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jul-31, Volume: 98, Issue:16

    Topics: Adenosine; Animals; Anxiety; Autoradiography; Behavior, Animal; Caffeine; Hippocampus; Hyperalgesia; Hypoxia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Purinergic P1

2001
Inhibition of caffeine-induced Ca2+ release by adenosine in mammalian skinned slow- and fast-twitch fibres.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 364, Issue:3

    Topics: Adenosine; Animals; Caffeine; Calcium; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Skeletal; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Vasodilator Agents

2001
Inhibition of adenosine deaminase attenuates endotoxin-induced release of cytokines in vivo in rats.
    Shock (Augusta, Ga.), 2001, Volume: 16, Issue:3

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Blood Pressure; Caffeine; Catecholamines; Cytokines; Endotoxemia; Endotoxins; Enzyme Inhibitors; Heart; Heart Rate; Male; Propranolol; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin; Xanthines

2001
Systemic adenosine given after ischemia protects renal function via A(2a) adenosine receptor activation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:3

    Topics: Adenosine; Analysis of Variance; Animals; Bucladesine; Caffeine; Kidney; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Reperfusion Injury; Vasodilation; Xanthines

2001
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines

2001
Adenosine and caffeine modulate circadian rhythms in the Syrian hamster.
    Neuroreport, 2001, Sep-17, Volume: 12, Issue:13

    Topics: Adenosine; Animals; Caffeine; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Mesocricetus; Motor Activity; Neurons; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sleep; Sleep Deprivation; Suprachiasmatic Nucleus

2001
Tubuloglomerular feedback in adenosine A1 receptor-deficient mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:5

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Feedback, Physiological; Glomerular Filtration Rate; Humans; Kidney Glomerulus; Kidney Tubules; Mice; Mice, Knockout; Receptors, Purinergic P1; Renin; Sodium

2001
Characterization of adenosine action in isolated rat renal artery. Possible role of adenosine A(2A) receptors.
    General pharmacology, 2000, Volume: 35, Issue:1

    Topics: Adenosine; Animals; Caffeine; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Indomethacin; Isotonic Solutions; Male; Models, Animal; Muscle Relaxation; Nitroarginine; Potassium Chloride; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Renal Artery; Tetraethylammonium; Vasodilator Agents; Xanthines

2000
Characteristics of irreversible ATP activation suggest that native skeletal ryanodine receptors can be phosphorylated via an endogenous CaMKII.
    Biophysical journal, 2001, Volume: 81, Issue:6

    Topics: Acid Phosphatase; Adenosine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Alleles; Animals; Binding, Competitive; Caffeine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Electrophysiology; Immunoblotting; Ligands; Lipid Bilayers; Muscle, Skeletal; Peptides; Phosphorylation; Protein Kinase C; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Swine; Time Factors

2001
In vivo labelling of the adenosine A2A receptor in mouse brain using the selective antagonist [3H]SCH 58261.
    The European journal of neuroscience, 2001, Volume: 14, Issue:9

    Topics: Adenosine; Animals; Binding Sites; Binding, Competitive; Blood-Brain Barrier; Brain; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazoles; Tritium

2001
Perinatal respiratory control and its modulation by adenosine and caffeine in the rat.
    Pediatric research, 2002, Volume: 51, Issue:1

    Topics: Adenosine; Animals; Animals, Newborn; Autoradiography; Brain Stem; Caffeine; Female; In Situ Hybridization; Pregnancy; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Respiration; Spinal Cord

2002
Distinct pharmacological mechanisms leading to c-fos gene expression in the fetal suprachiasmatic nucleus.
    Journal of biological rhythms, 2001, Volume: 16, Issue:6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Dizocilpine Maleate; Female; Gene Expression Regulation; Genes, fos; Image Processing, Computer-Assisted; In Situ Hybridization; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; RNA, Messenger; Suprachiasmatic Nucleus

2001
Dopaminergic mechanism for caffeine-produced cocaine seeking in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzazepines; Caffeine; Central Nervous System Stimulants; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Salicylamides; Self Administration; Theophylline; Vasodilator Agents

2002
Theacrine (1,3,7,9-tetramethyluric acid) synthesis in leaves of a Chinese tea, kucha (Camellia assamica var. kucha).
    Phytochemistry, 2002, Volume: 60, Issue:2

    Topics: Adenosine; Alkaloids; Beverages; Caffeine; Camellia; Carbon Radioisotopes; Methylation; Molecular Structure; Plant Leaves; Staining and Labeling; Time Factors; Uric Acid

2002
Chronic caffeine treatment causes changes in cardiac adenosine receptor function in rats.
    Pharmacology, 2002, Volume: 65, Issue:3

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Central Nervous System Stimulants; Female; Heart Rate; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Stimulation, Chemical

2002
Coronary function and adenosine receptor-mediated responses in ischemic-reperfused mouse heart.
    Cardiovascular research, 2002, Volume: 55, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Animals; Caffeine; Coronary Circulation; Heart; Male; Mice; Mice, Inbred C57BL; Models, Animal; Myocardial Contraction; Myocardial Reperfusion Injury; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Antagonists; Vasodilator Agents; Xanthines

2002
Differential aspects in ratio measurements of [Ca(2+)](i) relaxation in cardiomyocyte contraction following various drug treatments.
    Cell calcium, 2002, Volume: 31, Issue:6

    Topics: Adenosine; Algorithms; Animals; Animals, Newborn; Caffeine; Calcium; Cardiotonic Agents; Cells, Cultured; Chelating Agents; Cyclic AMP; Doxorubicin; Electric Stimulation; Enzyme Inhibitors; Indoles; Isoproterenol; Models, Theoretical; Muscle Contraction; Myocardium; Myocytes, Cardiac; Rats; Ryanodine; Thapsigargin

2002
Involvement of adenosine in the anti-allodynic effect of amitriptyline in streptozotocin-induced diabetic rats.
    Neuroscience letters, 2002, Aug-09, Volume: 328, Issue:2

    Topics: Adenosine; Amitriptyline; Analgesics; Animals; Antidepressive Agents, Tricyclic; Caffeine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Interactions; Female; Hyperalgesia; Neuralgia; Nociceptors; Pain Measurement; Pain Threshold; Peripheral Nerves; Phosphodiesterase Inhibitors; Physical Stimulation; Rats; Rats, Sprague-Dawley

2002
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine.
    Nature, 2002, Aug-15, Volume: 418, Issue:6899

    Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neostriatum; Nerve Tissue Proteins; Neurons; Phenethylamines; Phosphoproteins; Phosphorylation; Phosphothreonine; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P1; Triazoles

2002
Sedative, anticonvulsant and behaviour modifying effects of Centranthus longiflorus ssp. longiflorus: a study of comparison to diazepam.
    Die Pharmazie, 2002, Volume: 57, Issue:8

    Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Depression; Diazepam; Female; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Seizures; Sleep; Swimming; Thiopental; Turkey; Valerianaceae

2002
Contraction-related factors affect the concentration of a kallidin-like peptide in rat muscle tissue.
    The Journal of physiology, 2002, Oct-01, Volume: 544, Issue:Pt 1

    Topics: Adenosine; Animals; Bradykinin; Caffeine; Dose-Response Relationship, Drug; Electric Stimulation; Hydrogen-Ion Concentration; Kallidin; Male; Microdialysis; Muscle Contraction; Muscle, Skeletal; Osmolar Concentration; Rats; Rats, Wistar

2002
Supraspinal antinociceptive effects of mu and delta agonists involve modulation of adenosine uptake.
    Anesthesiology, 2003, Volume: 98, Issue:2

    Topics: Adenosine; Analgesics, Opioid; Animals; Brain Chemistry; Caffeine; Extracellular Space; Female; Injections; Injections, Intraventricular; Mice; Mice, Inbred C57BL; Pain Measurement; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Synaptosomes

2003
Chronic treatment with caffeine blunts the hyperlocomotor but not cognitive effects of the N-methyl-D-aspartate receptor antagonist MK-801 in mice.
    Psychopharmacology, 2003, Volume: 166, Issue:3

    Topics: Adenosine; Animals; Avoidance Learning; Caffeine; Central Nervous System Stimulants; Cognition; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Male; Maze Learning; Memory; Mice; Motor Activity; Postural Balance; Receptors, N-Methyl-D-Aspartate

2003
Up-regulation of striatal adenosine A(2A) receptors in schizophrenia.
    Neuroreport, 2003, Mar-03, Volume: 14, Issue:3

    Topics: Adenosine; Aged; Aged, 80 and over; Antipsychotic Agents; Cadaver; Caffeine; Control Groups; Corpus Striatum; Female; Humans; Male; Middle Aged; Phenethylamines; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Schizophrenia; Up-Regulation

2003
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:7

    Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines

2003
Adenosine inhibits activation-induced T cell expression of CD2 and CD28 co-stimulatory molecules: role of interleukin-2 and cyclic AMP signaling pathways.
    Journal of cellular biochemistry, 2003, Aug-01, Volume: 89, Issue:5

    Topics: Adenosine; Animals; Antibodies, Monoclonal; Caffeine; CD2 Antigens; CD28 Antigens; CD3 Complex; Cell Cycle; Colforsin; Cyclic AMP; Female; Flavins; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phenethylamines; Receptors, Interleukin-2; Receptors, Purinergic P1; Signal Transduction; T-Lymphocytes; Tyrosine

2003
Interactive role of adenosine and dopamine in the opiate withdrawal syndrome.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:2

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Chromatography, High Pressure Liquid; Dopamine; Injections, Subcutaneous; Male; Microdialysis; Morphine; Pyrimidines; Rats; Rats, Wistar; Receptors, Dopamine; Substance Withdrawal Syndrome; Triazoles

2003
Caffeine and coffee tolerance.
    Circulation, 2003, Aug-12, Volume: 108, Issue:6

    Topics: Adenosine; Baroreflex; Blood Pressure; Caffeine; Coffee; Drug Tolerance; Heart Rate; Humans; Hypertension; Infusions, Intravenous; Muscles; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Sympathetic Nervous System; Vasomotor System

2003
Effects of adenosine receptor antagonists on pial arteriolar dilation during carbon dioxide inhalation.
    European journal of pharmacology, 2003, Aug-29, Volume: 476, Issue:3

    Topics: Adenosine; Administration, Inhalation; Animals; Caffeine; Carbon Dioxide; Cerebral Cortex; Cerebral Veins; Cerebrovascular Circulation; Drug Interactions; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines

2003
[Administration of injectable gentisic acid combined preparation].
    Medizinische Klinik, 1957, Jul-26, Volume: 52, Issue:30

    Topics: Adenosine; Analgesics; Caffeine; Gentisates; Humans; Procaine

1957
THE EFFECT OF L-EPINEPHRINE AND OTHER AGENTS ON THE SYNTHESIS AND RELEASE OF ADENOSINE 3',5'-PHOSPHATE BY WHOLE PIGEON ERYTHROCYTES.
    The Journal of biological chemistry, 1963, Volume: 238

    Topics: Adenine Nucleotides; Adenosine; Animals; Birds; Caffeine; Columbidae; Epinephrine; Erythrocytes; Isoproterenol; Magnesium; Norepinephrine; Pharmacology; Phosphates; Probenecid; Research; Sympatholytics

1963
ACTIVATION OF AN EPINEPHRINE-SENSITIVE LIPOLYTIC ACTIVITY FROM ADIPOSE TISSUE BY ADENOSINE 3',5'-PHOSPHATE.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adipose Tissue; Caffeine; Calcium; Epididymis; Epinephrine; Humans; Lipid Metabolism; Lipolysis; Male; Pharmacology; Phosphates; Rats; Research; Theophylline

1964
EFFECTS OF CAFFEINE ON MAMMALIAN ATRIAL MUSCLE, AND ITS INTERACTION WITH ADENOSINE AND CALCIUM.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 148

    Topics: Acetylcholine; Adenosine; Aminohydrolases; Atropine; Caffeine; Calcium; Guinea Pigs; Heart Atria; Myocardium; Nucleosides; Pharmacology; Physostigmine; Research; Reserpine

1965
The effect of caffeine on peripheral vascular resistance in isolated perfused guinea pig hind limbs.
    Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:4

    Topics: Adenosine; Animals; Caffeine; Dose-Response Relationship, Drug; Female; Flavins; Guinea Pigs; Hindlimb; Hypoxia; Iliac Artery; Iloprost; Male; Nitrogen; Norepinephrine; Perfusion; Triazines; Triazoles; Vascular Resistance; Vasoconstriction; Vasodilation

2003
Antinociceptive effects of novel A2B adenosine receptor antagonists.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Analgesia; Animals; Caffeine; Drug Synergism; Male; Mice; Morphine; Pain

2004
Adenosine A2A receptors and depression.
    Neurology, 2003, Dec-09, Volume: 61, Issue:11 Suppl 6

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Depression; Disease Models, Animal; Dopamine Antagonists; Drug Interactions; Haloperidol; Mice; Mice, Knockout; Motor Activity; Neurotransmitter Agents; Parkinsonian Disorders; Purines; Pyrimidines; Receptor, Adenosine A2A; Triazines; Triazoles

2003
Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors.
    Neuroscience letters, 2004, Jan-23, Volume: 355, Issue:1-2

    Topics: Adenosine; Animals; Antidepressive Agents; Caffeine; Depressive Disorder; Disease Models, Animal; Female; Male; Mice; Motor Activity; Receptor, Adenosine A1; Receptor, Adenosine A2A; Stress, Psychological; Triazines; Triazoles; Xanthines

2004
Analgesic effect of caffeine and clomipramine: a possible interaction between adenosine and serotonin systems.
    Acta pharmaceutica (Zagreb, Croatia), 2003, Volume: 53, Issue:1

    Topics: Adenosine; Analgesia; Animals; Caffeine; Clomipramine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Injections, Intraperitoneal; Male; Mice; Pain Measurement; Reaction Time; Serotonin

2003
A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Feb-11, Volume: 24, Issue:6

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Caffeine; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Inflammation; Inflammation Mediators; Interleukin-1; Macrophages; Matrix Metalloproteinase 12; Metalloendopeptidases; Mice; Mice, Knockout; Microglia; Multiple Sclerosis; Myelin Sheath; Phenotype; Receptor, Adenosine A1; Recurrence; RNA, Messenger; Severity of Illness Index; Spinal Cord; Up-Regulation

2004
Interactions of nucleoside analogs, caffeine, and nicotine with human concentrative nucleoside transporters 1 and 2 stably produced in a transport-defective human cell line.
    Molecular pharmacology, 2004, Volume: 65, Issue:4

    Topics: Adenosine; Biological Transport; Caffeine; Dose-Response Relationship, Drug; Floxuridine; Humans; Membrane Transport Proteins; Molecular Sequence Data; Nicotine; Transfection; Tritium; Tumor Cells, Cultured; Uridine

2004
Involvement of adenosinergic A1 systems in the occurrence of respiratory perturbations encountered in newborns following an in utero caffeine exposure. a study on brainstem-spinal cord preparations isolated from newborn rats.
    Neuroscience, 2004, Volume: 127, Issue:2

    Topics: Adenosine; Animals; Animals, Newborn; Caffeine; Female; In Vitro Techniques; Medulla Oblongata; Neural Pathways; Pons; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-fos; Rats; Receptor, Adenosine A1; Respiratory Center; Respiratory Physiological Phenomena; Spinal Cord; Xanthines

2004
Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.
    European journal of pharmacology, 2004, Sep-19, Volume: 499, Issue:1-2

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Male; Maze Learning; Mice; Receptor, Adenosine A1; Triazines; Triazoles; Xanthines

2004
Effects of adenosine on optic nerve head circulation in rabbits.
    Experimental eye research, 2004, Volume: 79, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine A1 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Animals; Caffeine; Capillaries; Dose-Response Relationship, Drug; Glyburide; Injections; Injections, Intravenous; Optic Disk; Phenethylamines; Potassium Channels; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rabbits; Regional Blood Flow; Stimulation, Chemical; Vasodilation; Vitreous Body; Xanthines

2004
Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation.
    Journal of neurochemistry, 2004, Volume: 91, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Synaptic Transmission; Theophylline

2004
Reduction of the incidence of polyspermic penetration into porcine oocytes by pretreatment of fresh spermatozoa with adenosine and a transient co-incubation of the gametes with caffeine.
    Reproduction (Cambridge, England), 2004, Volume: 128, Issue:6

    Topics: Adenosine; Animals; Caffeine; Cell Culture Techniques; Cells, Cultured; Depression, Chemical; Female; Male; Microscopy, Fluorescence; Phosphodiesterase Inhibitors; Sperm-Ovum Interactions; Spermatozoa; Swine; Time Factors

2004
[Effect of caffeine on myocardial blood flow during pharmacological vasodilation].
    Zeitschrift fur Kardiologie, 2005, Volume: 94, Issue:2

    Topics: Adenosine; Caffeine; Coronary Circulation; Coronary Disease; Coronary Vessels; Drug Interactions; Humans; Hyperemia; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Male; Middle Aged; Positron-Emission Tomography; Vasodilation

2005
Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.
    British journal of pharmacology, 2005, Volume: 144, Issue:5

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Intraperitoneal; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines

2005
Effect of caffeine on cerebral blood flow response to somatosensory stimulation.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2005, Volume: 25, Issue:6

    Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Cerebrovascular Circulation; Electric Stimulation; Injections, Intravenous; Male; Physical Stimulation; Pia Mater; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Somatosensory Cortex; Theophylline; Vasodilation; Vasodilator Agents

2005
Modulation of short-term social memory in rats by adenosine A1 and A(2A) receptors.
    Neuroscience letters, 2005, Mar-16, Volume: 376, Issue:3

    Topics: Adenosine; Animals; Behavior, Animal; Brain; Caffeine; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intraperitoneal; Male; Memory, Short-Term; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Social Behavior; Triazines; Triazoles; Xanthines

2005
Effect of subchronic caffeine treatment on MK-801-induced changes in locomotion, cognition and ataxia in mice.
    Behavioural pharmacology, 2005, Volume: 16, Issue:2

    Topics: Adenosine; Amphetamine; Animals; Ataxia; Caffeine; Central Nervous System Stimulants; Cognition; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Humans; Locomotion; Male; Mice; Receptors, N-Methyl-D-Aspartate; Schizophrenia

2005
2-(1-Hexyn-1-yl)adenosine-induced intraocular hypertension is mediated via K+ channel opening through adenosine A2A receptor in rabbits.
    European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Alkynes; Animals; Antihypertensive Agents; Caffeine; Decanoic Acids; Glyburide; Hydroxy Acids; Hypotonic Solutions; Intraocular Pressure; Male; Ocular Hypertension; Phenethylamines; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rabbits; Receptor, Adenosine A2A; Sodium Chloride; Time Factors; Xanthines

2005
Mechanisms of adenosine-induced renal vasodilatation in hypertensive patients.
    Journal of hypertension, 2005, Volume: 23, Issue:9

    Topics: Adenosine; Adult; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Hypertension; Hypertension, Renovascular; Male; Middle Aged; omega-N-Methylarginine; Renal Circulation; Time Factors; Vasodilation

2005
Consequences of prolonged caffeine administration and its withdrawal on pilocarpine- and kainate-induced seizures in rats.
    Epilepsia, 2005, Volume: 46, Issue:9

    Topics: Adenosine; Animals; Caffeine; Coffea; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Epilepsy, Temporal Lobe; Kainic Acid; Male; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Substance Withdrawal Syndrome

2005
Presynaptic mechanism of action induced by 5-HT in nerve terminals: possible involvement of ryanodine and IP3 sensitive 2+ stores.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2005, Volume: 142, Issue:3

    Topics: Adenosine; Animals; Astacoidea; Caffeine; Calcium Channels; Inositol 1,4,5-Trisphosphate Receptors; Membrane Potentials; Neuromuscular Junction; Presynaptic Terminals; Receptors, Cytoplasmic and Nuclear; Ryanodine; Ryanodine Receptor Calcium Release Channel; Serotonin

2005
A structural study of new potent and selective antagonists to the A2B adenosine receptor.
    Acta crystallographica. Section B, Structural science, 2005, Volume: 61, Issue:Pt 5

    Topics: Acetamides; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Asparagine; Caffeine; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Histidine; Humans; Hydrogen Bonding; Kinetics; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Binding; Theophylline; Xanthines

2005
A detailed behavioral analysis of the acute motor effects of caffeine in the rat: involvement of adenosine A1 and A2A receptors.
    Psychopharmacology, 2005, Volume: 183, Issue:2

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Xanthines

2005
Reversion of levodopa-induced motor fluctuations by the A2A antagonist CSC is associated with an increase in striatal preprodynorphin mRNA expression in 6-OHDA-lesioned rats.
    Synapse (New York, N.Y.), 2006, Jun-01, Volume: 59, Issue:7

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine; Adrenergic Agents; Animals; Caffeine; Corpus Striatum; Dynorphins; Dyskinesias; Enkephalins; Immunohistochemistry; In Situ Hybridization; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; RNA, Messenger

2006
Effect of caffeine on leg muscle pain during cycling exercise among females.
    Medicine and science in sports and exercise, 2006, Volume: 38, Issue:3

    Topics: Adenosine; Adolescent; Adult; Analgesics; Bicycling; Caffeine; Double-Blind Method; Exercise Test; Female; Georgia; Humans; Leg; Pain Measurement

2006
In vitro evaluation of adenosine 5'-monophosphate as an imaging agent of tumor metabolism.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Caffeine; Carbon Radioisotopes; Cell Line, Tumor; Female; Humans; Immunophenotyping; In Vitro Techniques; Models, Biological; Neoplasm Metastasis; Neoplasms; Positron-Emission Tomography; Time Factors

2006
Effect of caffeine on ischemia detection by adenosine single-photon emission computed tomography perfusion imaging.
    Journal of the American College of Cardiology, 2006, Jun-06, Volume: 47, Issue:11

    Topics: Adenosine; Aged; Caffeine; Coffee; Drinking; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Single-Blind Method; Time Factors; Tomography, Emission-Computed, Single-Photon

2006
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis.
    British journal of pharmacology, 2006, Volume: 148, Issue:8

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Cell Line; Chromatography, High Pressure Liquid; Ethanol; Hepatocytes; Humans; Liver Cirrhosis; Matrix Metalloproteinases, Membrane-Associated; Methotrexate; Mice; Mice, Inbred C57BL; Rats; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; Thioacetamide; Triazines; Triazoles

2006
Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.
    Journal of neurochemistry, 2006, Volume: 98, Issue:2

    Topics: Adenosine; Animals; Caffeine; Carotid Body; Catecholamines; Central Nervous System Stimulants; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Hypoxia; Immunohistochemistry; Male; Potassium; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Presynaptic; Respiratory Mechanics; Triazines; Triazoles; Xanthines

2006
Beta-amyloid treatment sensitizes mice to amphetamine-induced locomotion but reduces response to caffeine.
    Neuro-degenerative diseases, 2004, Volume: 1, Issue:1

    Topics: Adenosine; Adrenergic Agents; Alzheimer Disease; Amphetamine; Amyloid beta-Peptides; Animals; Avoidance Learning; Brain; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Glutamine; Injections, Intraventricular; Male; Mice; Motor Activity; Psychotic Disorders

2004
Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production.
    Neuroscience, 2006, Nov-03, Volume: 142, Issue:4

    Topics: Adenosine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Brain; Caffeine; Cell Line, Tumor; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Memory Disorders; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Neuropsychological Tests; Peptide Fragments; Presenilin-1; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Treatment Outcome

2006
Adenosine A2A receptors are expressed in human atrial myocytes and modulate spontaneous sarcoplasmic reticulum calcium release.
    Cardiovascular research, 2006, Nov-01, Volume: 72, Issue:2

    Topics: Adenosine; Aged; Caffeine; Calcium; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; Female; Heart Atria; Humans; Immunohistochemistry; Isoquinolines; Male; Microscopy, Confocal; Middle Aged; Myocytes, Cardiac; Patch-Clamp Techniques; Phenethylamines; Receptors, Adenosine A2; Reverse Transcriptase Polymerase Chain Reaction; Ryanodine; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Stimulation, Chemical; Sulfonamides

2006
Evidence for adenosine- and serotonin-mediated antihyperalgesic effects of cizolirtine in rats suffering from diabetic neuropathy.
    Neuropharmacology, 2007, Volume: 52, Issue:2

    Topics: Adenosine; Analgesics; Animals; Area Under Curve; Caffeine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hyperalgesia; Male; Oxadiazoles; Pain Measurement; Pain Threshold; Piperazines; Psychomotor Performance; Pyrazoles; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Vocalization, Animal

2007
Protective effects of caffeine on chronic hypoxia-induced perinatal white matter injury.
    Annals of neurology, 2006, Volume: 60, Issue:6

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Asphyxia Neonatorum; Brain; Caffeine; Cell Differentiation; Cell Lineage; Chronic Disease; Disease Models, Animal; Female; Humans; Hypoxia, Brain; Infant, Newborn; Leukomalacia, Periventricular; Mice; Mice, Inbred C57BL; Nerve Fibers, Myelinated; Neuroprotective Agents; Oligodendroglia; Pregnancy; Receptor, Adenosine A1; Stem Cells

2006
Involvement of adenosinergic receptor system in an animal model of tardive dyskinesia and associated behavioural, biochemical and neurochemical changes.
    European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3

    Topics: Adenosine; Akathisia, Drug-Induced; Animals; Antioxidants; Behavior, Animal; Brain; Caffeine; Catalase; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Haloperidol; Lipid Peroxidation; Male; Mastication; Maze Learning; Motor Activity; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Purinergic P1; Stereotyped Behavior; Superoxide Dismutase; Vasodilator Agents

2006
Hyperalgesia, low-anxiety, and impairment of avoidance learning in neonatal caffeine-treated rats.
    Psychopharmacology, 2007, Volume: 191, Issue:1

    Topics: Adenosine; Animals; Animals, Newborn; Anxiety; Avoidance Learning; Behavior, Animal; Body Temperature Regulation; Brain; Caffeine; Central Nervous System Stimulants; Female; Hot Temperature; Hyperalgesia; Male; Memory; Motor Activity; Pain Measurement; Pain Threshold; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Time Factors

2007
Evaluation of neuronal phosphoproteins as effectors of caffeine and mediators of striatal adenosine A2A receptor signaling.
    Brain research, 2007, Jan-19, Volume: 1129, Issue:1

    Topics: Adenosine; Animals; Antihypertensive Agents; Caffeine; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Phenethylamines; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Presynaptic Terminals; Receptor, Adenosine A2A; Synaptic Membranes; Up-Regulation

2007
Effect of 2-(6-cyano-1-hexyn-1-yl)adenosine on ocular blood flow in rabbits.
    Life sciences, 2007, Feb-27, Volume: 80, Issue:12

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Eye; Flavins; Intraocular Pressure; Male; Rabbits; Regional Blood Flow; Retinal Vessels; Vasodilator Agents; Xanthines

2007
Differential glutamate-dependent and glutamate-independent adenosine A1 receptor-mediated modulation of dopamine release in different striatal compartments.
    Journal of neurochemistry, 2007, Volume: 101, Issue:2

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Caffeine; Corpus Striatum; Dopamine; Glutamic Acid; Male; Microdialysis; Nucleus Accumbens; Phosphodiesterase Inhibitors; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Adenosine A1; Synaptic Transmission; Theophylline

2007
"One" cup of coffee and nuclear SPECT to go.
    Journal of the American College of Cardiology, 2007, Jan-30, Volume: 49, Issue:4

    Topics: Adenosine; Caffeine; Coffee; Humans; Tomography, Emission-Computed, Single-Photon

2007
Sex differences in mouse heart rate and body temperature and in their regulation by adenosine A1 receptors.
    Acta physiologica (Oxford, England), 2007, Volume: 190, Issue:1

    Topics: Adenosine; Animals; Body Temperature; Caffeine; Central Nervous System Stimulants; Female; Genotype; Heart Rate; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Receptor, Adenosine A1; Sex Characteristics

2007
Adenosine stimulates the basolateral 50 pS K channels in the thick ascending limb of the rat kidney.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenylyl Cyclases; Algorithms; Animals; Bucladesine; Caffeine; Dose-Response Relationship, Drug; Enzyme Activation; Female; Kidney; Male; Patch-Clamp Techniques; Phenethylamines; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adenosine A2; Stimulation, Chemical; Xanthines

2007
Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.
    Molecular pharmacology, 2007, Volume: 72, Issue:2

    Topics: Adenosine; Caffeine; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Extracellular Signal-Regulated MAP Kinases; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Receptor, Adenosine A2B; Receptor, Adenosine A3; Vascular Endothelial Growth Factor A

2007
The 1976C>T polymorphism in the adenosine A2A receptor gene does not affect the vasodilator response to adenosine in humans in vivo.
    Pharmacogenetics and genomics, 2007, Volume: 17, Issue:7

    Topics: Adenosine; Adult; Alleles; AMP Deaminase; Base Sequence; Caffeine; DNA Primers; Female; Genotype; Humans; Male; Pharmacogenetics; Polymorphism, Single Nucleotide; Receptor, Adenosine A2A; Vasodilation

2007
Involvement of adenosinergic receptors in anxiety related behaviours.
    Indian journal of experimental biology, 2007, Volume: 45, Issue:5

    Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Female; Male; Maze Learning; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline

2007
The participation of adenosine receptors in the adenosine 5'-triphosphate-induced relaxation in the isolated rabbit corpus cavernosum penis.
    International journal of urology : official journal of the Japanese Urological Association, 2007, Volume: 14, Issue:8

    Topics: Acetamides; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Animals; Caffeine; Flavins; Male; Muscle Relaxation; Muscle, Smooth; Penile Erection; Penis; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Purines; Rabbits; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Receptors, Purinergic P2

2007
The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors.
    Behavioural brain research, 2007, Dec-11, Volume: 185, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Amphetamine; Animals; Antipsychotic Agents; Attention; Caffeine; Central Nervous System Stimulants; Choice Behavior; Dopamine; Dose-Response Relationship, Drug; Male; Motor Activity; Phenethylamines; Psychomotor Performance; Purines; Rats; Reaction Time; Reflex, Startle; Xanthines

2007
Modulation of adenosine-induced responses in the guinea-pig trachea during long-term caffeine treatment: possible role of epithelium.
    Journal of pharmacological sciences, 2007, Volume: 105, Issue:3

    Topics: Adenosine; Animals; Body Weight; Caffeine; Capsaicin; Cromolyn Sodium; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Nitroarginine; Trachea

2007
Transient inhibition of astrocytogenesis in developing mouse brain following postnatal caffeine exposure.
    Pediatric research, 2007, Volume: 62, Issue:5

    Topics: Adenosine; Animals; Animals, Newborn; Apoptosis; Astrocytes; Behavior, Animal; Body Weight; Brain; Caffeine; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Immunohistochemistry; Injections, Intraperitoneal; Mice; Microtubule-Associated Proteins; Models, Animal; Nerve Growth Factors; Organ Size; Phenethylamines; Pyrimidines; Receptor, Adenosine A2A; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Synaptophysin; Time Factors; Triazoles

2007
Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, May-15, Volume: 32, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Aniline Compounds; Animals; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Dipyridamole; Female; Male; Mice; Motor Activity; Nucleoside Transport Proteins; Receptor, Adenosine A1; Receptor, Adenosine A2A; Swimming; Triazines; Triazoles; Xanthines; Zinc

2008
Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:12

    Topics: Adenosine; Adolescent; Adult; Anxiety Disorders; Brain; Brain Chemistry; Caffeine; DNA Mutational Analysis; Dopamine; Dose-Response Relationship, Drug; Female; Genetic Predisposition to Disease; Genetic Testing; Genetic Variation; Genotype; Humans; Male; Phosphodiesterase Inhibitors; Polymorphism, Genetic; Receptor, Adenosine A2A; Receptors, Dopamine D2; Self-Assessment; Young Adult

2008
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
    European journal of pharmacology, 2008, Apr-14, Volume: 584, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Carotid Arteries; Consciousness; Cytidine; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theobromine; Theophylline; Time Factors; Triazines; Triazoles; Uridine; Ventricular Function, Left; Ventricular Pressure; Xanthines

2008
Caffeine induction of Cyp6a2 and Cyp6a8 genes of Drosophila melanogaster is modulated by cAMP and D-JUN protein levels.
    Gene, 2008, May-31, Volume: 415, Issue:1-2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Bucladesine; Caffeine; Cell Line; Cyclic AMP; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 6; Drosophila melanogaster; Drosophila Proteins; Enzyme Inhibitors; Gene Expression Regulation; Genes, Insect; Intracellular Space; Mixed Function Oxygenases; Models, Genetic; Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Transcription, Genetic

2008
Caffeine stimulates cytochrome oxidase expression and activity in the striatum in a sexually dimorphic manner.
    Molecular pharmacology, 2008, Volume: 74, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Base Pairing; Caffeine; Electron Transport Complex IV; Female; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Inbred C57BL; Neostriatum; PC12 Cells; Phenethylamines; Promoter Regions, Genetic; Rats; RNA, Messenger; RNA, Small Interfering; Sex Characteristics; Time Factors; Transcription, Genetic; Up-Regulation

2008
The antinociceptive interaction of anandamide and adenosine at the spinal level.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:3

    Topics: Adenosine; Analgesics; Animals; Arachidonic Acids; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Hot Temperature; Inflammation; Injections, Spinal; Male; Pain; Pain Measurement; Polyunsaturated Alkamides; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Reaction Time

2009
An antagonistic interaction between A2B adenosine and D2 dopamine receptors modulates the function of rat carotid body chemoreceptor cells.
    Journal of neurochemistry, 2008, Volume: 107, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Acetamides; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Carotid Body; Catecholamines; Chemoreceptor Cells; Cyclic AMP; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptor, Adenosine A2B; Receptors, Dopamine D2; Tritium; Vasodilator Agents

2008
Sex differences in cognitive estimation during sleep deprivation: effects of stimulant countermeasures.
    The International journal of neuroscience, 2008, Volume: 118, Issue:11

    Topics: Adenosine; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Cognition Disorders; Dextroamphetamine; Dopamine; Female; Humans; Male; Mental Processes; Modafinil; Neuropsychological Tests; Placebos; Prefrontal Cortex; Sex Characteristics; Sleep Deprivation; Stress, Psychological; Wakefulness; Young Adult

2008
Modulation of insulin release by adenosine A1 receptor agonists and antagonists in INS-1 cells: the possible contribution of 86Rb+ efflux and 45Ca2+ uptake.
    Cell biochemistry and function, 2008, Volume: 26, Issue:8

    Topics: 3T3-L1 Cells; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Antineoplastic Agents; Caffeine; Calcium; Calcium Channels; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Insulin; Mice; Potassium Channels; Rats; Rats, Wistar; Receptor, Adenosine A1; Rubidium; Xanthines

2008
Enhancing brain adenosine signaling with the nucleoside transport blocker NBTI (S-(4-nitrobenzyl)-6-theoinosine) mimics the effects of inescapable shock on later shuttle-escape performance in rats.
    Behavioral neuroscience, 2008, Volume: 122, Issue:6

    Topics: Adenosine; Analysis of Variance; Animals; Behavior, Animal; Brain; Caffeine; Electroshock; Escape Reaction; Freezing Reaction, Cataleptic; Male; Nucleoside Transport Proteins; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Reaction Time; Signal Transduction; Thioinosine; Xanthines

2008
High-dose adenosine overcomes the attenuation of myocardial perfusion reserve caused by caffeine.
    Journal of the American College of Cardiology, 2008, Dec-09, Volume: 52, Issue:24

    Topics: Adenosine; Aged; Caffeine; Central Nervous System Stimulants; Coffee; Coronary Artery Disease; Coronary Vessels; Drug Interactions; Female; Humans; Hyperemia; Male; Middle Aged; Myocardial Infarction; Myocardial Perfusion Imaging; Prospective Studies; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Vasodilation; Vasodilator Agents

2008
Drosophila D1 dopamine receptor mediates caffeine-induced arousal.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Dec-23, Volume: 105, Issue:51

    Topics: Adenosine; Animals; Arousal; Caffeine; Dopamine; Down-Regulation; Drosophila Proteins; Methamphetamine; Mutation; Neurotransmitter Agents; Organisms, Genetically Modified; Receptors, Dopamine

2008
Modification of the cardiovascular response of posterior hypothalamic adenosine A(2A) receptor stimulation by adenylate cyclase and KATP channel blockade in anesthetized rats.
    Autonomic neuroscience : basic & clinical, 2009, Mar-12, Volume: 146, Issue:1-2

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aminoquinolines; Anesthesia, Inhalation; Animals; Blood Pressure; Bradycardia; Caffeine; Glipizide; Guanylate Cyclase; Heart Rate; Hypothalamus, Posterior; Imines; KATP Channels; Male; Microinjections; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A

2009
Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jan-21, Volume: 29, Issue:3

    Topics: Acetylcholine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Arousal; Behavior, Animal; Caffeine; Chromatography, High Pressure Liquid; Electroencephalography; Electromyography; Male; Mice; Microdialysis; Phenethylamines; Phosphodiesterase Inhibitors; Prefrontal Cortex; Receptor, Adenosine A1; Receptors, Adenosine A2; Spectrum Analysis; Triazines; Triazoles; Xanthines

2009
Blocking adenosine A2A receptor reduces peritoneal fibrosis in two independent experimental models.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:8

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cells, Cultured; Central Nervous System Stimulants; Chlorhexidine; Collagen; Disease Models, Animal; Fibroblasts; Fibrosis; Mice; Mice, Knockout; Peritoneal Cavity; Phenethylamines; Vasodilator Agents

2009
Transgenic expression of human equilibrative nucleoside transporter 1 in mouse neurons.
    Journal of neurochemistry, 2009, Volume: 109, Issue:2

    Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Equilibrative Nucleoside Transporter 1; Ethanol; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; Neurons; PC12 Cells; Rats; Receptors, Purinergic P1; Up-Regulation

2009
Optimal dosing of desvenlafaxine, new insights in gambling and anorexia, and caffeine-induced psychosis.
    CNS spectrums, 2009, Volume: 14, Issue:3

    Topics: Adenosine; Anorexia; Antidepressive Agents, Second-Generation; Caffeine; Central Nervous System Stimulants; Cyclohexanols; Ethnicity; Gambling; Humans; Psychoses, Substance-Induced; Venlafaxine Hydrochloride

2009
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
    Current drug safety, 2009, Volume: 4, Issue:2

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline

2009
Adenosine receptor interactions alter cardiac contractility in rat heart.
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Caffeine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flavins; Imines; In Vitro Techniques; Male; Myocardial Contraction; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Stimulation, Chemical

2010
Differential effects of adenosine antagonists in two models of parkinsonian tremor.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 94, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Synergism; Jaw; Male; Parkinsonian Disorders; Pimozide; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Tacrine; Theophylline; Tremor; Triazoles

2009
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance.
    Epilepsia, 2010, Volume: 51, Issue:3

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of Death; Death, Sudden; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Kainic Acid; Mice; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Risk Factors; Seizures; Survival Analysis; Tubercidin

2010
Recent caffeine ingestion reduces adenosine efficacy in the treatment of paroxysmal supraventricular tachycardia.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:1

    Topics: Adenosine; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Caffeine; Case-Control Studies; Female; Humans; Male; Middle Aged; Surveys and Questionnaires; Tachycardia, Supraventricular; Time Factors

2010
Control of cannabinoid CB1 receptor function on glutamate axon terminals by endogenous adenosine acting at A1 receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jan-13, Volume: 30, Issue:2

    Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzoxazines; Biophysics; CA1 Region, Hippocampal; Caffeine; Calcium Channel Blockers; Dronabinol; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Piperidines; Presynaptic Terminals; Propanolamines; Pyrazoles; Quinoxalines; Receptor, Adenosine A1; Receptor, Cannabinoid, CB1; Xanthines

2010
Adenosine and caffeine-induced paroxysmal supraventricular tachycardia.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:5

    Topics: Adenosine; Anti-Arrhythmia Agents; Caffeine; Humans; Tachycardia, Supraventricular

2010
A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:7

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatic Artery; Liver Cirrhosis, Experimental; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Portal Vein; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Vascular Resistance; Vasodilation; Vasodilator Agents

2010
Acupuncture for mice.
    Nature, 2010, Jun-03, Volume: 465, Issue:7298

    Topics: Acupuncture Therapy; Adenosine; Animals; Caffeine; Humans; Mice; Models, Animal; Pain; Pain Management; Pentostatin; Placebo Effect; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1

2010
Rapid determination of adenosine deaminase kinetics using fast-scan cyclic voltammetry.
    Physical chemistry chemical physics : PCCP, 2010, Sep-14, Volume: 12, Issue:34

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Caffeine; Cattle; Electric Conductivity; Electrochemistry; Enzyme Assays; Kinetics; Oxidation-Reduction; Pentostatin; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Silver; Time Factors

2010
Capacitation inducers act through diverse intracellular mechanisms in cryopreserved bovine sperm.
    Theriogenology, 2010, Oct-01, Volume: 74, Issue:6

    Topics: Adenosine; Animals; Bicarbonates; Caffeine; Cattle; Chlortetracycline; Cryopreservation; Female; Fertilization in Vitro; Fluorescence; Heparin; Intracellular Fluid; Male; Semen; Semen Analysis; Semen Preservation; Signal Transduction; Sperm Capacitation; Superoxides

2010
Adenosine A(1) receptors in human brain and transfected CHO cells: Inhibition of [(3)H]CPFPX binding by adenosine and caffeine.
    Neuroscience letters, 2011, Jan-10, Volume: 487, Issue:3

    Topics: Adenosine; Animals; Binding, Competitive; Brain; Caffeine; CHO Cells; Cricetinae; Cricetulus; Humans; Positron-Emission Tomography; Radiopharmaceuticals; Receptor, Adenosine A1; Transfection; Tritium; Xanthines

2011
Caffeine-induced natriuresis and diuresis via blockade of hepatic adenosine-mediated sensory nerves and a hepatorenal reflex.
    Canadian journal of physiology and pharmacology, 2010, Volume: 88, Issue:11

    Topics: Adenosine; Animals; Caffeine; Diuresis; Kidney; Liver; Male; Natriuresis; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reflex

2010
What's new in Shock, September 2011?
    Shock (Augusta, Ga.), 2011, Volume: 36, Issue:3

    Topics: Adenosine; Animals; Caffeine; Humans; Myocardial Reperfusion Injury; Neutrophils; Shock; Stem Cells

2011
Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds.
    BMC developmental biology, 2012, Jan-23, Volume: 12

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Deaminase; Caffeine; Cell Adhesion; Cell Adhesion Molecules; Cell Division; Cell Enlargement; Chemotactic Factors; Cyclic AMP; Cytoplasmic Streaming; Cytosol; Dictyostelium; Glucose; Protozoan Proteins; Signal Transduction

2012
The effect of caffeine on adenosine myocardial perfusion imaging: time to reassess?
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2012, Volume: 19, Issue:3

    Topics: Adenosine; Caffeine; Coronary Artery Disease; Coronary Circulation; Exercise Test; Female; Humans; Male; Myocardial Perfusion Imaging

2012
ATP depletion triggers acute myeloid leukemia differentiation through an ATR/Chk1 protein-dependent and p53 protein-independent pathway.
    The Journal of biological chemistry, 2012, Jul-06, Volume: 287, Issue:28

    Topics: Acute Disease; Adenosine; Adenosine Triphosphate; Antibiotics, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Caffeine; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Comet Assay; DNA Damage; Doxorubicin; HEK293 Cells; Humans; Leukemia, Myeloid; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Signal Transduction; Staurosporine; Thioinosine; Tumor Suppressor Protein p53

2012
The effect of vasoactive agents on post-pressure hyperemia.
    Microvascular research, 2012, Volume: 84, Issue:3

    Topics: Adenosine; Alprostadil; Animals; Area Under Curve; Arterial Pressure; Buffers; Caffeine; Dinoprostone; Dopamine; Epinephrine; Humans; Hyperemia; Microdialysis; NG-Nitroarginine Methyl Ester; Phosphates; Rats; Rats, Wistar; Regional Blood Flow; Skin; Time Factors; Vasoconstrictor Agents

2012
Chronic caffeine intake in adult rat inhibits carotid body sensitization produced by chronic sustained hypoxia but maintains intact chemoreflex output.
    Molecular pharmacology, 2012, Volume: 82, Issue:6

    Topics: Acclimatization; Adenosine; Animals; Caffeine; Carotid Body; Carotid Sinus; Chemoreceptor Cells; Dopamine; Down-Regulation; Ganglion Cysts; Hypercapnia; Hyperventilation; Hypoxia; Partial Pressure; Pulmonary Ventilation; Rats; Rats, Wistar; Receptors, Purinergic P1; Up-Regulation

2012
Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Oct-03, Volume: 32, Issue:40

    Topics: Adenosine; Amino Acid Chloromethyl Ketones; Amnesia, Anterograde; Amygdala; Animals; Caffeine; Caspase 1; Caspase Inhibitors; Conditioning, Classical; Cues; Enzyme Activation; Fear; Hypoxia, Brain; Interleukin 1 Receptor Antagonist Protein; Male; MAP Kinase Signaling System; Maze Learning; Mental Recall; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxygen; Receptors, Interleukin-1 Type I; Receptors, Purinergic P1; Recognition, Psychology; Theobromine; Xanthines

2012
Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors.
    Physical therapy, 2013, Volume: 93, Issue:3

    Topics: Adenosine; Analysis of Variance; Animals; Ankle Joint; Caffeine; Clonidine; Disease Models, Animal; Fenclonine; Hyperalgesia; Male; Mice; Morphine; Pain, Postoperative; Receptor, Adenosine A1; Xanthines; Yohimbine

2013
Reduced sleep and low adenosinergic sensitivity in cacna1a R192Q mutant mice.
    Sleep, 2013, Jan-01, Volume: 36, Issue:1

    Topics: Adenosine; Analysis of Variance; Animals; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Disease Models, Animal; Electroencephalography; Electromyography; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Sleep Deprivation; Sleep Stages; Sleep, REM; Sodium Chloride

2013
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
    Neuroscience, 2013, Mar-27, Volume: 234

    Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines

2013
Effects of adenosine receptor antagonists on the in vivo LPS-induced inflammation model of Parkinson's disease.
    Neurotoxicity research, 2013, Volume: 24, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Corpus Striatum; Dopamine; Dopaminergic Neurons; Glutamic Acid; Hydroxyl Radical; Inflammation; Lipopolysaccharides; Male; Microinjections; Parkinson Disease; Purines; Rats; Receptor, Adenosine A2A

2013
Caffeine, exercise and the brain.
    Nestle Nutrition Institute workshop series, 2013, Volume: 76

    Topics: Adenosine; Attention; Brain; Caffeine; Central Nervous System Stimulants; Dopamine; Exercise; Fatigue; Humans; Motivation; Muscle, Skeletal; Musculoskeletal Pain; Physical Endurance; Plant Extracts; Purinergic P1 Receptor Antagonists

2013
Caffeine induces alveolar apoptosis in the hyperoxia-exposed developing mouse lung.
    Pediatric research, 2014, Volume: 75, Issue:3

    Topics: Adenosine; Animals; Animals, Newborn; Apoptosis; Bronchoalveolar Lavage; Caffeine; In Situ Nick-End Labeling; Mice; Pulmonary Alveoli; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Signal Transduction

2014
Use of 11C-MPDX and PET to study adenosine A1 receptor occupancy by nonradioactive agonists and antagonists.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2014, Volume: 55, Issue:2

    Topics: Adenosine; Allosteric Site; Animals; Brain; Caffeine; Carbon Radioisotopes; Ethanol; Heart Rate; Male; Morpholines; Positron-Emission Tomography; Pyrimidines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptor, Adenosine A1; Xanthines

2014
Combined alcohol and energy drink use: hedonistic motives, adenosine, and alcohol dependence.
    Alcoholism, clinical and experimental research, 2014, Volume: 38, Issue:7

    Topics: Adenosine; Alcohol Drinking; Alcoholism; Caffeine; Drinking Behavior; Energy Drinks; Ethanol; Humans; Motivation; Philosophy; Pleasure; Purinergic P1 Receptor Antagonists; Reward; Risk Factors; Self Administration

2014
Modulation of 3',5'-cyclic AMP homeostasis in human platelets by coffee and individual coffee constituents.
    The British journal of nutrition, 2014, Nov-14, Volume: 112, Issue:9

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Deaminase; Adult; Blood Platelets; Caffeine; Coffee; Cyclic AMP; Homeostasis; Humans; Phosphodiesterase Inhibitors; Pyrazines; Signal Transduction

2014
Expression and characterization of purinergic receptors in rat middle meningeal artery-potential role in migraine.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Adenosine; Animals; Caffeine; Intracellular Space; Male; Meningeal Arteries; Migraine Disorders; Purine Nucleotides; Pyrimidine Nucleotides; Rats, Sprague-Dawley; Receptors, Purinergic; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2014
Effect of caffeine on intravenous adenosine-induced hyperemia in fractional flow reserve measurement.
    The Journal of invasive cardiology, 2014, Volume: 26, Issue:11

    Topics: Adenosine; Administration, Oral; Aged; Blood Pressure; Caffeine; Coronary Angiography; Coronary Stenosis; Dose-Response Relationship, Drug; Female; Fractional Flow Reserve, Myocardial; Humans; Hyperemia; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Papaverine; Premedication; Prospective Studies

2014
Adenosine signaling in reserpine-induced depression in rats.
    Behavioural brain research, 2015, Jun-01, Volume: 286

    Topics: Adenosine; Adrenergic Uptake Inhibitors; Animals; Brain; Caffeine; Depressive Disorder; Dose-Response Relationship, Drug; Flavins; Male; Neuropsychological Tests; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Random Allocation; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reserpine; Swimming; Theophylline

2015
Ablation of androgen receptor gene triggers right ventricular outflow tract ventricular tachycardia.
    International journal of cardiology, 2015, Jun-15, Volume: 189

    Topics: Action Potentials; Adenosine; Animals; Caffeine; Calcium; Flecainide; Gene Knockdown Techniques; Gene Knockout Techniques; Isoproterenol; Male; Mice; Mice, Knockout; Receptors, Androgen; Tachycardia, Ventricular; Ventricular Dysfunction, Left

2015
Effect of adenosine system in the action of oseltamivir on behavior in mice.
    Neuroscience letters, 2015, Jul-10, Volume: 599

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Antiviral Agents; Behavior, Animal; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Neuraminidase; Oseltamivir; Phenethylamines; Pyrimidines; Receptors, Adenosine A2; Triazoles; Walking

2015
Adenosinergic regulation of binge-like ethanol drinking and associated locomotor effects in male C57BL/6J mice.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 135

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Alcohol Drinking; Animals; Binge Drinking; Caffeine; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Purinergic P1; Sucrose; Xanthines

2015
Is Caffeine Abstention Necessary Before Adenosine-Induced Fractional Flow Reserve Measurement?
    Journal of the American College of Cardiology, 2015, Oct-27, Volume: 66, Issue:17

    Topics: Adenosine; Caffeine; Fractional Flow Reserve, Myocardial; Humans; Hyperemia; Papaverine; Prospective Studies; Receptors, Purinergic P1; Vasodilator Agents

2015
Activation of adenosine A₂A receptors suppresses the emission of pro-social and drug-stimulated 50-kHz ultrasonic vocalizations in rats: possible relevance to reward and motivation.
    Psychopharmacology, 2016, Volume: 233, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Amphetamine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Interpersonal Relations; Male; Morphine; Motivation; Motor Activity; Narcotics; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Reward; Social Behavior; Vocalization, Animal

2016
Caffeine does not significantly reduce the sensitivity of vasodilator stress myocardial perfusion imaging.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2016, Volume: 23, Issue:3

    Topics: Adenosine; Caffeine; Coronary Circulation; Exercise Test; Myocardial Perfusion Imaging; Vasodilator Agents

2016
Caffeine intake and myocardial perfusion imaging.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2016, Volume: 23, Issue:3

    Topics: Adenosine; Caffeine; Coronary Circulation; Myocardial Perfusion Imaging; Perfusion

2016
Caffeine exposure alters adenosine system and neurochemical markers during retinal development.
    Journal of neurochemistry, 2016, Volume: 138, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Animals; Caffeine; Chick Embryo; Chickens; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptor, Adenosine A2A; Retina

2016
Susceptibility to seizure-induced sudden death in DBA/2 mice is altered by adenosine.
    Epilepsy research, 2016, Volume: 124

    Topics: Adenosine; Animals; Caffeine; Death, Sudden; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Male; Mice, Inbred DBA; Purinergic P1 Receptor Antagonists; Pyrazoles; Pyrimidines; Receptors, Purinergic P1; Respiration; Respiration Disorders; Seizures; Tubercidin; Xanthines

2016
Caffeine intake inverts the effect of adenosine on myocardial perfusion during stress as measured by T1 mapping.
    The international journal of cardiovascular imaging, 2016, Volume: 32, Issue:10

    Topics: Adenosine; Aged; Aged, 80 and over; Caffeine; Case-Control Studies; Coffee; Coronary Circulation; False Negative Reactions; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Ischemia; Myocardial Perfusion Imaging; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Vasodilator Agents

2016
Hold off on that shot of Java: more evidence that caffeine intake leads to false negative adenosine stress myocardial perfusion.
    The international journal of cardiovascular imaging, 2017, Volume: 33, Issue:1

    Topics: Adenosine; Caffeine; Coronary Circulation; Exercise Test; Humans; Myocardial Perfusion Imaging; Predictive Value of Tests; Vasodilator Agents

2017
Characterization of particulate-phase polycyclic aromatic hydrocarbons emitted from incense burning and their bioreactivity in RAW264.7 macrophage.
    Environmental pollution (Barking, Essex : 1987), 2017, Volume: 220, Issue:Pt B

    Topics: Adenosine; Air Pollutants; Air Pollution, Indoor; Alcohols; Aldehydes; Amides; Animals; Caffeine; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Imidazoles; Ketones; Macrophages; Mice; Molecular Weight; Nitric Oxide; Particulate Matter; Polycyclic Aromatic Hydrocarbons; Smoke; Taiwan; Tumor Necrosis Factor-alpha

2017
Homeostatic response to sleep/rest deprivation by constant water flow in larval zebrafish in both dark and light conditions.
    Journal of sleep research, 2017, Volume: 26, Issue:3

    Topics: Adenosine; Animals; Arousal; Caffeine; Circadian Rhythm; Darkness; Homeostasis; Larva; Light; Models, Animal; Phenylalanine; Receptor, Adenosine A1; Reflex, Startle; Rest; Sleep; Sleep Deprivation; Wakefulness; Water Movements; Zebrafish

2017
Effects of caffeine intake prior to stress cardiac magnetic resonance perfusion imaging on regadenoson- versus adenosine-induced hyperemia as measured by T1 mapping.
    The international journal of cardiovascular imaging, 2017, Volume: 33, Issue:11

    Topics: Adenosine; Aged; Caffeine; Coffee; Coronary Artery Disease; Coronary Circulation; Female; Humans; Hyperemia; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Perfusion Imaging; Predictive Value of Tests; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Pyrazoles; Reproducibility of Results; Time Factors; Vasodilator Agents

2017
The Effects of Adenosinergic Modulation on Cytokine Levels in a Pentylenetetrazole-Induced Generalized Tonic-Clonic Seizure Model.
    Neuroimmunomodulation, 2017, Volume: 24, Issue:1

    Topics: Adenosine; Animals; Brain; Caffeine; Central Nervous System Stimulants; Convulsants; Cytokines; Disease Models, Animal; Drug Interactions; Male; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Seizures

2017
Theacrine: A purine alkaloid from Camellia assamica var. kucha with a hypnotic property via the adenosine system.
    Neuroscience letters, 2017, 10-17, Volume: 659

    Topics: Adenosine; Alkaloids; Animals; Caffeine; Camellia; Drug Synergism; Hippocampus; Male; Mice; Pentobarbital; Pyrimidines; Rats; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazoles; Uric Acid; Xanthines

2017
Treatment with A
    Cell death & disease, 2017, 10-05, Volume: 8, Issue:10

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Humans; Inflammation; Ischemia; Male; Microglia; Nitrobenzenes; Pyridines; Rats; Receptor, Adenosine A2A; Reperfusion Injury; Retina; Retinal Diseases

2017
Disagreement between splenic switch-off and myocardial T1-mapping after caffeine intake.
    The international journal of cardiovascular imaging, 2018, Volume: 34, Issue:4

    Topics: Adenosine; Aged; Caffeine; Case-Control Studies; Coffee; Coronary Circulation; Female; Hemodynamics; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Ischemia; Myocardial Perfusion Imaging; Observer Variation; Predictive Value of Tests; Purinergic P1 Receptor Antagonists; Reproducibility of Results; Spleen; Vasodilator Agents

2018
Effects of caffeine on the detection of ischemia in patients undergoing adenosine stress cardiovascular magnetic resonance imaging.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2017, Dec-18, Volume: 19, Issue:1

    Topics: Adenosine; Aged; Caffeine; Central Nervous System Stimulants; Coronary Circulation; Electrocardiography; Exercise Test; Female; Humans; Magnetic Resonance Imaging, Cine; Male; Myocardial Ischemia; Predictive Value of Tests; Vasodilator Agents

2017
Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation.
    European journal of pharmacology, 2018, Mar-05, Volume: 822

    Topics: 5'-Nucleotidase; Adenosine; Animals; Caffeine; Cerebellum; Female; Fever; Gait; Lactation; Mothers; Motor Activity; Oxidative Stress; Pregnancy; Rats; Receptor, Adenosine A2A; Seizures; Time Factors

2018
Adenosine A
    Molecular neurobiology, 2019, Volume: 56, Issue:2

    Topics: Adenosine; Caffeine; Cells, Cultured; Dopamine; Humans; Motor Neurons; Neurons, Efferent; Receptors, Dopamine D1; Spinal Cord; Synaptic Transmission

2019
Caffeine and high intensity exercise: Impact on purinergic and cholinergic signalling in lymphocytes and on cytokine levels.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Acetylcholinesterase; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Caffeine; Cell Proliferation; Cytokines; Glucocorticoids; Hydrolysis; Lymphocyte Activation; Lymphocytes; Male; Physical Conditioning, Animal; Rats, Wistar; Receptors, Cholinergic; Receptors, Purinergic; Signal Transduction

2018
Prediction of self-assembly of adenosine analogues in solution: a computational approach validated by isothermal titration calorimetry.
    Physical chemistry chemical physics : PCCP, 2019, Feb-20, Volume: 21, Issue:8

    Topics: Adenosine; Caffeine; Calorimetry; Dimerization; Models, Molecular; Molecular Structure; Solvents; Structure-Activity Relationship; Surface Properties; Theophylline; Thermodynamics; Water

2019
Dose-Dependent Effect of Caffeine on Adenosine-Induced Myocardial Stress Perfusion in Rubidium-82 Positron-Emission Tomography/Computed Tomography.
    JACC. Cardiovascular imaging, 2019, Volume: 12, Issue:6

    Topics: Adenosine; Administration, Oral; Adult; Caffeine; Coronary Circulation; Dose-Response Relationship, Drug; Female; Healthy Volunteers; Humans; Male; Myocardial Perfusion Imaging; Positron Emission Tomography Computed Tomography; Predictive Value of Tests; Radiopharmaceuticals; Random Allocation; Reproducibility of Results; Rubidium Radioisotopes; Vasodilator Agents; Young Adult

2019
The science of tea's mood-altering magic.
    Nature, 2019, Volume: 566, Issue:7742

    Topics: Adenosine; Affect; Alpha Rhythm; Animals; Antioxidants; Behavior; Beta Rhythm; Blood-Brain Barrier; Caffeine; Catechin; Cognition; Dementia; Depression; Exercise; gamma-Aminobutyric Acid; Glutamates; Humans; Hydrocortisone; Life Style; Mental Health; Middle Aged; Stress, Psychological; Tea; Theta Rhythm

2019
Caffeine Treatment Promotes Differentiation and Maturation of Hypoxic Oligodendrocytes via Counterbalancing Adenosine 1 Adenosine Receptor-Induced Calcium Overload.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Mar-06, Volume: 25

    Topics: Adenosine; Animals; Caffeine; Calcium; Cell Differentiation; Cells, Cultured; China; Homeostasis; Hypoxia; Myelin Sheath; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Calcium-Sensing; Receptors, Purinergic P1

2019
Effect of Caffeine Ingestion on Relative Myocardial Blood Flow Imaging.
    JACC. Cardiovascular imaging, 2019, Volume: 12, Issue:5

    Topics: Adenosine; Caffeine; Positron Emission Tomography Computed Tomography; Rubidium Radioisotopes

2019
The Authors' Reply.
    JACC. Cardiovascular imaging, 2019, Volume: 12, Issue:5

    Topics: Adenosine; Caffeine; Positron Emission Tomography Computed Tomography; Rubidium Radioisotopes

2019
Lipotoxicity-associated inflammation is prevented by guarana (
    Drug and chemical toxicology, 2021, Volume: 44, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperlipidemias; Inflammation; Lymphocytes; Male; Rats; Rats, Wistar; Simvastatin; Theobromine; Theophylline

2021
Impact of caffeine on myocardial perfusion reserve assessed by semiquantitative adenosine stress perfusion cardiovascular magnetic resonance.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2019, 06-24, Volume: 21, Issue:1

    Topics: Adenosine; Aged; Caffeine; Coronary Circulation; Female; Humans; Hyperemia; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Ischemia; Myocardial Perfusion Imaging; Predictive Value of Tests; Prospective Studies; Purinergic P1 Receptor Antagonists; Reproducibility of Results; Vasodilation; Vasodilator Agents

2019
Blood Flow Reserve at Common Caffeine Levels.
    JACC. Cardiovascular imaging, 2019, Volume: 12, Issue:8 Pt 1

    Topics: Adenosine; Caffeine; Positron-Emission Tomography; Rubidium Radioisotopes; Tomography

2019
Hypnotic Effects of
    Nutrients, 2019, Oct-09, Volume: 11, Issue:10

    Topics: Adenosine; Animals; Caffeine; DNA, Bacterial; Gene Expression; Hypnotics and Sedatives; Limosilactobacillus fermentum; Locomotion; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Real-Time Polymerase Chain Reaction; Signal Transduction; Sleep; Sleep Aids, Pharmaceutical

2019
Caffeine Exacerbates Postictal Hypoxia.
    Neuroscience, 2019, 12-01, Volume: 422

    Topics: Adenosine; Animals; CA1 Region, Hippocampal; Caffeine; Dose-Response Relationship, Drug; Hypoxia; Kindling, Neurologic; Male; Oxygen; Phenethylamines; Pyrimidines; Rats; Receptors, Adenosine A2; Seizures; Triazoles

2019
Potential beneficial effects of caffeine administration in the neonatal period of an animal model of schizophrenia.
    Behavioural brain research, 2020, 08-05, Volume: 391

    Topics: Adenosine; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Locomotion; Male; Motor Activity; Rats; Rats, Inbred SHR; Rats, Wistar; Schizophrenia

2020
Effects of the excitation or inhibition of basal forebrain cholinergic neurons on cognitive ability in mice exposed to chronic intermittent hypoxia.
    Brain research bulletin, 2020, Volume: 164

    Topics: Acetylcholine; Adenosine; Animals; Apoptosis; Caffeine; Cholinergic Neurons; Cognition; Endoplasmic Reticulum Stress; Hypoxia, Brain; Male; Maze Learning; Mice; Oxidative Stress

2020
Effects of gestational and breastfeeding caffeine exposure in adenosine A1 agonist-induced antinociception of infant rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2020, Volume: 80, Issue:8

    Topics: Adenosine; Animals; Caffeine; Female; Lactation; Pregnancy; Rats; Rats, Wistar; Receptor, Adenosine A1

2020
Electrophysiological signatures of acute systemic lipopolysaccharide-induced inflammation: potential implications for delirium science.
    British journal of anaesthesia, 2021, Volume: 126, Issue:5

    Topics: Adenosine; Age Factors; Animals; Caffeine; Cerebral Cortex; Cytokines; Delirium; Disease Models, Animal; Electroencephalography; Electrophysiological Phenomena; Humans; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Piroxicam; Prostaglandins; Wakefulness

2021
Linear concentration-response relationship of serum caffeine with adenosine-induced fractional flow reserve overestimation: a comparison with papaverine.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2021, Dec-03, Volume: 17, Issue:11

    Topics: Adenosine; Caffeine; Coronary Angiography; Coronary Stenosis; Fractional Flow Reserve, Myocardial; Humans; Hyperemia; Papaverine; Predictive Value of Tests; Vasodilator Agents

2021
The effects of caffeine on bone mineral density and fracture risk.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2022, Volume: 33, Issue:6

    Topics: Adenosine; Adult; Bone Density; Caffeine; Coffee; Fractures, Bone; Humans; Osteoporosis

2022
Adenosine A
    Movement disorders : official journal of the Movement Disorder Society, 2022, Volume: 37, Issue:4

    Topics: Adenosine; Caffeine; Coffee; Humans; Parkinson Disease; Receptor, Adenosine A2A

2022
Image-derived and physiological markers to predict adequate adenosine-induced hyperemic response in Rubidium-82 myocardial perfusion imaging.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022, Volume: 29, Issue:6

    Topics: Adenosine; Biomarkers; Caffeine; Coronary Circulation; Humans; Myocardial Perfusion Imaging; Positron-Emission Tomography; Rubidium Radioisotopes; Tomography, X-Ray Computed; Vasodilator Agents

2022
Caffeine excites medial parabrachial nucleus neurons of mice by blocking adenosine A1 receptor.
    Brain research, 2022, 09-01, Volume: 1790

    Topics: Adenosine; Animals; Apnea; Caffeine; Mice; Neurons; Parabrachial Nucleus; Receptor, Adenosine A1; Receptor, Adenosine A2A

2022
Adenosine-caffeine: the agonist-antagonist couple for vasodilator stress tests.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2023, Volume: 30, Issue:2

    Topics: Adenosine; Caffeine; Exercise Test; Humans; Vasodilator Agents

2023
General Label-Free Fluorescent Aptamer Binding Assay Using Cationic Conjugated Polymers.
    Analytical chemistry, 2022, 11-08, Volume: 94, Issue:44

    Topics: Adenosine; Aptamers, Nucleotide; Biosensing Techniques; Caffeine; Cations; Hydrocortisone; Polymers

2022
Changes in adenosine receptors and neurotrophic factors in the SOD1G93A mouse model of amyotrophic lateral sclerosis: Modulation by chronic caffeine.
    PloS one, 2022, Volume: 17, Issue:12

    Topics: Adenosine; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Caffeine; Disease Models, Animal; Mice; Mice, Transgenic; Receptors, Purinergic P1; Spinal Cord; Superoxide Dismutase; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2022
Effects of Chronic Caffeine Consumption on Synaptic Function, Metabolism and Adenosine Modulation in Different Brain Areas.
    Biomolecules, 2023, 01-04, Volume: 13, Issue:1

    Topics: Adenosine; Animals; Caffeine; Hippocampus; Male; Mice; Prospective Studies; Receptors, Purinergic P1

2023
Chemoimmunotherapy with doxorubicin and caffeine combination enhanced ICD induction and T-cell infiltration in B16F10 melanoma tumors.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:5

    Topics: Adenosine; Animals; Caffeine; Doxorubicin; Immunogenic Cell Death; Melanoma; Mice; T-Lymphocytes; Tumor Microenvironment

2023
Selective Deuteration Improves the Affinity of Adenosine A
    Journal of chemical information and modeling, 2023, 05-22, Volume: 63, Issue:10

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Caffeine; Ligands; Receptor, Adenosine A2A

2023
Acute caffeine differently affects risk-taking and the expression of BDNF and of adenosine and opioid receptors in rats with high or low anxiety-like behavior.
    Pharmacology, biochemistry, and behavior, 2023, Volume: 227-228

    Topics: Adenosine; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Caffeine; Rats; Receptors, Opioid; Receptors, Purinergic P1; Risk-Taking; RNA, Messenger

2023
Cross-Binding of Four Adenosine/ATP Aptamers to Caffeine, Theophylline, and Other Methylxanthines.
    Biochemistry, 2023, 08-01, Volume: 62, Issue:15

    Topics: Adenosine; Adenosine Triphosphate; Aptamers, Nucleotide; Caffeine; Theophylline

2023
Cross-Binding of Adenosine by Aptamers Selected Using Theophylline.
    Chembiochem : a European journal of chemical biology, 2023, Dec-01, Volume: 24, Issue:23

    Topics: Adenosine; Aptamers, Nucleotide; Caffeine; Nucleotide Motifs; Theophylline

2023
Caffeine-folic acid-loaded-chitosan nanoparticles combined with methotrexate as a novel HepG2 immunotherapy targeting adenosine A2A receptor downstream cascade.
    BMC complementary medicine and therapies, 2023, Oct-27, Volume: 23, Issue:1

    Topics: Adenosine; Caffeine; Chitosan; Folic Acid; Humans; Immunotherapy; Methotrexate; Molecular Docking Simulation; Nanoparticles; Neoplasms; Receptor, Adenosine A2A; Tumor Microenvironment

2023
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