Compounds > bz-423
Page last updated: 2024-09-04

bz-423 and pk 11195

bz-423 has been researched along with pk 11195 in 2 studies

Compound Research Comparison

Studies
(bz-423)		Trials
(bz-423)		Recent Studies (post-2010)
(bz-423)		Studies
(pk 11195)		Trials
(pk 11195)		Recent Studies (post-2010) (pk 11195)
560141,06311259

Protein Interaction Comparison

ProteinTaxonomybz-423 (IC50)pk 11195 (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.005
Translocator proteinRattus norvegicus (Norway rat)0.003
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.005
Translocator proteinHomo sapiens (human)0.1645
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.005
Nuclear receptor subfamily 1 group I member 3 Homo sapiens (human)0.39
GABA theta subunitRattus norvegicus (Norway rat)0.005
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.005

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blatt, NB; Boitano, A; Dineen, TA; Ellman, JA; Emal, CD; Glick, GD; Leonetti, F; Opipari, AW; Roush, WR1
Cleary, J; Glick, GD; Johnson, KM; Opipari, AW1

Other Studies

2 other study(ies) available for bz-423 and pk 11195

ArticleYear
Structure activity studies of a novel cytotoxic benzodiazepine.
    Bioorganic & medicinal chemistry letters, 2003, Oct-06, Volume: 13, Issue:19

    Topics: Animals; Arthritis; Benzodiazepines; Cell Death; Lupus Vulgaris; Structure-Activity Relationship

2003
Inhibition of the mitochondrial F1F0-ATPase by ligands of the peripheral benzodiazepine receptor.
    Bioorganic & medicinal chemistry letters, 2007, Mar-15, Volume: 17, Issue:6

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Benzodiazepines; Cell Line, Tumor; Cell Proliferation; GABA-A Receptor Antagonists; Humans; Hydrolysis; Isoquinolines; Kinetics; Ligands; Mitochondria; Proton-Translocating ATPases; Structure-Activity Relationship

2007
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