bryostatin-1 has been researched along with nonane* in 1 studies
1 other study(ies) available for bryostatin-1 and nonane
Article | Year |
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Synthesis of the bryostatin 1 northern hemisphere (C1-C16) via desymmetrization by ketalization/ring-closing metathesis.
[reaction: see text] Synthesis of the northern hemisphere (C1-C16) of bryostatin 1, a potent anticancer agent, has been accomplished in 14 steps and 11% overall yield via desymmetrization by ketalization/ring-closing metathesis. A 2,9-dioxabicyclo[3.3.1]nonane template facilitated stereoselective A-ring functionalization, while an efficient hetero-Diels-Alder reaction was used to elaborate the B-ring. Topics: Acetals; Alkanes; Antineoplastic Agents; Bridged Bicyclo Compounds; Bryostatins; Cyclization; Macrolides; Molecular Structure | 2004 |