Page last updated: 2024-08-25

broxaterol and isoxazoles

broxaterol has been researched along with isoxazoles in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199012 (33.33)18.7374
1990's23 (63.89)18.2507
2000's1 (2.78)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crotti, P; Fracchia, C; Gurrieri, G; Nava, S; Rampulla, C1
Decramer, M; Derom, E; Gurrieri, G; Janssens, S; Tjandramaga, TB1
Ansalone, D; Gurrieri, G; Petraglia, A; Pisati, R; Scarpitta, M1
Crippa, L; De Biase, D; Flores D'Arcais, A; Romagnoni, G1
Cappelletti, G; Fornasini, G; Galimberti, C; Hanozet, G; Parenti, P1
Barnes, PJ; Brown, AC; Chung, KF; Hui, KP; Ventresca, P1
Gazzaniga, A; Luisi, PL; Stroppolo, F; Walde, P; Willimann, H1
Bianco, S; Fai, V; Gambaro, G; Lodola, E; Pisati, R; Robuschi, M; Scuri, M; Spagnotto, S1
Carenzi, A; Della Bella, D; Moriggi, E; Sala, R1
Burni, B; Dottorini, ML; Grassi, V; Gurrieri, G; Malerba, M; Peccini, F; Sorbini, CA; Tantucci, C1
Ansalone, D; Calvanese, RC; Federico, S; Galzerano, V; Gurrieri, G; Petraglia, A; Scarpitta, M; Zinno, A1
Borgia, M; Simone, P; Torre, L; Ventresca, GP1
Della Bella, D1
Löfdahl, CG; Sigvaldasson, A; Skoogh, BE; Svedmyr, N1
Bianco, S1
Ziment, I1
Allegra, L1
Corsico, R; Lodola, E; Majani, U; Rampulla, C1
Bianco, S; Robuschi, M; Simone, P; Vaghi, A; Ventresca, GP1
Bründler, H; Godly, R; Herzog, H; Imhof, E; Perruchoud, AP1
Cafaggi, R; D'Onofrio, V; Giosuè, S; Guerrini, P; Perrone, N; Scano, M1
Casali, L; Colombo, ML; Manazza, P; Rossi, A; Zoia, MC1
Chetta, A; Cuomo, A; Garavaldi, G; Gurrieri, G; Olivieri, D1
Bianco, S; Gambaro, G; Lodola, E; Pisati, R; Robuschi, M; Scuri, M; Spagnotto, S1
Boni, E; Filippi, B; Giustina, A; Grassi, V; Malerba, M; Politi, A; Romagnoni, G; Tantucci, C1
Benedetti, M; Boner, AL; Comis, A; Marcer, G; Spezia, E1
Duranti, R; Gigliotti, F; Gorini, M; Gurrieri, G; Scano, G1
Biasin, C; Ferrari, M; Lo Cascio, V; Lodola, E; Olivieri, M; Pisati, R1
Pavord, ID; Tattersfield, AE; Wahedna, I; Wisniewski, AF; Wong, CS1
Bresciani, E; Desenzani, P; Giustina, A; Grassi, V; Licini, M; Malerba, M; Zaltieri, G1
Boni, E; Filippi, B; Grassi, V; Malerba, M; Romagnoni, G; Tantucci, C1
de Bock, V; Decramer, M; Derom, E; Gayan-Ramirez, G; Gurrieri, G1
Ganassini, A; Rossi, A1
Conti, P; Dallanoce, C; De Amici, M; De Micheli, C; Klotz, KN1
Behr, B; Hoffmann, C; Klotz, KN; Ottolina, G1

Reviews

3 review(s) available for broxaterol and isoxazoles

ArticleYear
Broxaterol: pharmacological profile of a unique structural feature.
    Respiration; international review of thoracic diseases, 1989, Volume: 55 Suppl 2

    Topics: Adrenergic beta-Agonists; Animals; Asthma; Bronchodilator Agents; Humans; Isoxazoles; Oxazoles; Structure-Activity Relationship

1989
Role of broxaterol in bronchial hyperresponsiveness.
    Respiration; international review of thoracic diseases, 1989, Volume: 55 Suppl 2

    Topics: Adrenergic beta-Agonists; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agents; Double-Blind Method; Humans; Isoxazoles; Oxazoles; Randomized Controlled Trials as Topic

1989
Broxaterol: therapeutic trials and safety profile.
    Respiration; international review of thoracic diseases, 1989, Volume: 55 Suppl 2

    Topics: Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Child; Double-Blind Method; Humans; Isoxazoles; Oxazoles; Randomized Controlled Trials as Topic

1989

Trials

21 trial(s) available for broxaterol and isoxazoles

ArticleYear
Effect of a beta 2-agonist (broxaterol) on respiratory muscle strength and endurance in patients with COPD with irreversible airway obstruction.
    Chest, 1992, Volume: 101, Issue:1

    Topics: Adrenergic beta-Agonists; Aged; Carbon Dioxide; Double-Blind Method; Humans; Isoxazoles; Lung Diseases, Obstructive; Middle Aged; Muscle Contraction; Oxygen; Respiratory Mechanics; Respiratory Muscles

1992
Bronchodilation and beta 2-selectivity of broxaterol in asthmatics: a crossover, single-blind, terbutaline- and placebo-controlled study.
    International journal of clinical pharmacology, therapy, and toxicology, 1992, Volume: 30, Issue:10

    Topics: Adrenergic beta-Agonists; Adult; Airway Resistance; Asthma; Blood Pressure; Bronchi; Bronchodilator Agents; Female; Forced Expiratory Volume; Heart Rate; Humans; Isoxazoles; Male; Middle Aged; Single-Blind Method; Terbutaline; Time Factors

1992
Bronchodilating activity of broxaterol transdermal patch and its protective effect on bronchial constriction induced by inhaled distilled water mist.
    International journal of clinical pharmacology, therapy, and toxicology, 1991, Volume: 29, Issue:10

    Topics: Administration, Cutaneous; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchoconstriction; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Nebulizers and Vaporizers; Spirometry

1991
Dose-response comparison of broxaterol and salbutamol pressurized aerosols.
    European journal of clinical pharmacology, 1990, Volume: 39, Issue:6

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aerosols; Albuterol; Blood Pressure; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Tolerance; Female; Forced Expiratory Volume; Humans; Isoxazoles; Male; Middle Aged; Pulse; Vital Capacity

1990
Broxaterol, a new beta 2-adrenoceptor agonist compared to salbutamol in asthmatics, oral and inhalation treatment.
    Respiration; international review of thoracic diseases, 1989, Volume: 55 Suppl 2

    Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Albuterol; Asthma; Double-Blind Method; Humans; Isoxazoles; Oxazoles; Randomized Controlled Trials as Topic

1989
Role of broxaterol in bronchial hyperresponsiveness.
    Respiration; international review of thoracic diseases, 1989, Volume: 55 Suppl 2

    Topics: Adrenergic beta-Agonists; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agents; Double-Blind Method; Humans; Isoxazoles; Oxazoles; Randomized Controlled Trials as Topic

1989
Broxaterol: therapeutic trials and safety profile.
    Respiration; international review of thoracic diseases, 1989, Volume: 55 Suppl 2

    Topics: Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Child; Double-Blind Method; Humans; Isoxazoles; Oxazoles; Randomized Controlled Trials as Topic

1989
Broxaterol: a double-blind clinical trial comparing broxaterol and salbutamol.
    Respiration; international review of thoracic diseases, 1985, Volume: 47, Issue:4

    Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Blood Pressure; Bronchitis; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory Volume; Heart Rate; Humans; Isoxazoles; Male; Middle Aged; Oxazoles; Pulse; Random Allocation; Spirometry; Time Factors

1985
Evaluation of a new bronchodilating compound (broxaterol) administered as a pressurized aerosol.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:2

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchi; Bronchitis; Bronchospirometry; Double-Blind Method; Drug Evaluation; Forced Expiratory Volume; Humans; Isoxazoles; Maximal Midexpiratory Flow Rate; Middle Aged; Oxazoles; Random Allocation; Vital Capacity

1987
Broxaterol (Z.1170), a new oral beta 2-agonist compared with salbutamol.
    Respiration; international review of thoracic diseases, 1987, Volume: 51, Issue:2

    Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Double-Blind Method; Female; Hemodynamics; Humans; Isoxazoles; Lung Diseases, Obstructive; Male; Middle Aged; Oxazoles; Random Allocation; Respiratory Function Tests

1987
A comparison of the bronchodilator effects of broxaterol and salbutamol.
    International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:2

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Blood Pressure; Bronchodilator Agents; Female; Heart Rate; Humans; Isoxazoles; Lung Diseases, Obstructive; Male; Middle Aged; Oxazoles; Respiratory Function Tests; Time Factors

1988
Early bronchodilating effect of a new oral beta-2-receptor agonist (broxaterol) in bronchial asthma.
    Respiration; international review of thoracic diseases, 1988, Volume: 53, Issue:4

    Topics: Administration, Oral; Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Female; Humans; Isoxazoles; Male; Middle Aged; Oxazoles

1988
The protective effect of transdermal broxaterol on exercise-induced bronchoconstriction.
    European journal of clinical pharmacology, 1995, Volume: 47, Issue:5

    Topics: Administration, Cutaneous; Adolescent; Adrenergic beta-Agonists; Asthma; Bronchoconstriction; Child; Cross-Over Studies; Double-Blind Method; Exercise; Female; Humans; Isoxazoles; Male

1995
Effects of beta 2-agonists during cardiopulmonary exercise test in COPD patients.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1994, Volume: 49, Issue:5

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Exercise Test; Female; Humans; Isoxazoles; Lung Diseases, Obstructive; Male; Middle Aged

1994
Preliminary study on the effect of broxaterol on bronchial hyperresponsiveness in asthmatic children: influence of allergen exposure.
    Respiration; international review of thoracic diseases, 1993, Volume: 60, Issue:6

    Topics: Adolescent; Adrenergic beta-Agonists; Allergens; Asthma; Bronchial Hyperreactivity; Child; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Isoxazoles; Male; Maximal Midexpiratory Flow Rate; Peak Expiratory Flow Rate; Pilot Projects; Vital Capacity

1993
Effects of intravenous broxaterol on respiratory drive and neuromuscular coupling in COPD patients.
    The European respiratory journal, 1993, Volume: 6, Issue:3

    Topics: Adrenergic beta-Agonists; Double-Blind Method; Electromyography; Heart Rate; Humans; Isoxazoles; Lung Diseases, Obstructive; Male; Middle Aged; Respiratory Function Tests; Respiratory Mechanics; Respiratory Muscles

1993
Evaluation of the bronchodilating activity and the tolerability of broxaterol administered as a solution by inhalation.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:5

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aged; Asthma; Blood Pressure; Bronchitis; Bronchodilator Agents; Double-Blind Method; Female; Forced Expiratory Volume; Heart Rate; Humans; Isoxazoles; Male; Maximal Expiratory Flow Rate; Middle Aged; Vital Capacity

1993
Asthma control during and after cessation of regular beta 2-agonist treatment.
    The American review of respiratory disease, 1993, Volume: 148, Issue:3

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Analysis of Variance; Asthma; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Humans; Isoxazoles; Male; Middle Aged; Peak Expiratory Flow Rate; Time Factors

1993
Effect of two beta 2-agonist drugs, salbutamol and broxaterol, on the growth hormone response to exercise in adult patients with asthmatic bronchitis.
    Journal of endocrinological investigation, 1995, Volume: 18, Issue:11

    Topics: Adolescent; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Bronchitis; Chronic Disease; Cross-Over Studies; Double-Blind Method; Exercise; Exercise Test; Female; Growth Hormone; Hormones; Humans; Isoxazoles; Male; Middle Aged

1995
Ineffectiveness of intravenous beta 2-agonists on improving exercise tolerance in patients with reversible chronic airway obstruction.
    Respiration; international review of thoracic diseases, 1996, Volume: 63, Issue:1

    Topics: Adrenergic beta-Agonists; Aged; Airway Obstruction; Albuterol; Blood Gas Analysis; Chronic Disease; Cross-Over Studies; Double-Blind Method; Exercise Tolerance; Female; Humans; Infusions, Intravenous; Isoxazoles; Male; Middle Aged; Spirometry

1996
Short-term regular beta 2-adrenergic agonists treatment is safe in mild asthmatics taking low doses of inhaled steroids.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1997, Volume: 34, Issue:1

    Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Adult; Asthma; Beclomethasone; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Isoxazoles; Male; Middle Aged; Respiratory Mechanics; Vital Capacity

1997

Other Studies

14 other study(ies) available for broxaterol and isoxazoles

ArticleYear
Effects of broxaterol and theophylline on fatigued canine diaphragm in vivo. A randomized, controlled study.
    The American review of respiratory disease, 1992, Volume: 146, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Diaphragm; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Isoxazoles; Muscle Contraction; Random Allocation; Theophylline

1992
[Pharmacokinetics of broxaterol in asthmatic children].
    Minerva pediatrica, 1992, Volume: 44, Issue:9

    Topics: Adolescent; Adrenergic beta-Agonists; Asthma; Child; Female; Humans; Isoxazoles; Male

1992
Uptake of broxaterol by cultured human cells.
    Biochemistry international, 1992, Volume: 28, Issue:3

    Topics: Adrenergic beta-Agonists; Cells, Cultured; Humans; Hydrogen-Ion Concentration; Isoxazoles; Liver; Models, Biological; Sodium

1992
Modulation of neurally mediated airway microvascular leakage in guinea-pig airways by beta 2-adrenoceptor agonists.
    Agents and actions, 1992, Volume: 36, Issue:1-2

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Capillaries; Electric Stimulation; Evans Blue; Guinea Pigs; In Vitro Techniques; Isoxazoles; Male; Neurons; Propranolol; Respiratory System; Substance P; Tachykinins; Vagus Nerve

1992
Lecithin organogel as matrix for transdermal transport of drugs.
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:9

    Topics: Adult; Biological Transport; Female; Gels; Humans; Isoxazoles; Pharmaceutical Vehicles; Phosphatidylcholines; Scopolamine; Skin Absorption

1992
The specific binding of broxaterol, a new beta 2-selective agonist, to beta-adrenoceptors.
    European journal of pharmacology, 1991, Oct-02, Volume: 203, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Dihydroalprenolol; In Vitro Techniques; Isoxazoles; Lung; Male; Myocardium; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Thermodynamics

1991
Acute ventilatory and gas-exchange effects of a new beta-2 agonist, broxaterol, in asthmatics.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:3

    Topics: Adrenergic beta-Agonists; Adult; Aged; Asthma; Female; Humans; Injections, Intravenous; Intermittent Positive-Pressure Breathing; Isoxazoles; Male; Middle Aged; Pulmonary Gas Exchange; Respiratory Function Tests

1990
Negligible metabolic effects of long-term oral treatment with a new beta 2-agonist: broxaterol.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:5

    Topics: Acid-Base Equilibrium; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Airway Obstruction; Blood Glucose; Bronchial Spasm; Cholesterol; Electrolytes; Fatty Acids, Nonesterified; Female; Glycerol; Heart Rate; Humans; Insulin; Isoxazoles; Male; Metabolism; Middle Aged; Respiratory Function Tests; Triglycerides

1990
Broxaterol: a new beta2-adrenoceptor agonist for the treatment of reversible airways disease. Proceedings of the satellite symposium. Budapest, September 8, 1988.
    Respiration; international review of thoracic diseases, 1989, Volume: 55 Suppl 2

    Topics: Adrenergic beta-Agonists; Asthma; Bronchitis; Humans; Isoxazoles; Oxazoles

1989
Remarks on broxaterol.
    Respiration; international review of thoracic diseases, 1989, Volume: 55 Suppl 2

    Topics: Adrenergic alpha-Agonists; Asthma; Bronchodilator Agents; Humans; Isoxazoles; Oxazoles

1989
[Comparison of the effectiveness and tolerance of a new beta-2 stimulant (broxaterol) vs. salbutamol in patients with chronic obstructive bronchopneumopathy].
    La Clinica terapeutica, 1987, Apr-15, Volume: 121, Issue:1

    Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Female; Forced Expiratory Volume; Humans; Isoxazoles; Lung Diseases, Obstructive; Male; Middle Aged; Oxazoles; Vital Capacity

1987
Broxaterol increases force output of fatigued canine diaphragm more than salbutamol.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Diaphragm; Dogs; Isoxazoles; Muscle Contraction; Muscle Fatigue

1997
Synthesis of new delta 2-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic receptor antagonists.
    Bioorganic & medicinal chemistry, 1998, Volume: 6, Issue:4

    Topics: Adenylyl Cyclases; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; CHO Cells; Chromatography, Thin Layer; Cricetinae; Glioma; Humans; Isoxazoles; Magnetic Resonance Spectroscopy; Pindolol; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Tumor Cells, Cultured

1998
Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation.
    The Journal of biological chemistry, 2006, Jun-30, Volume: 281, Issue:26

    Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; Aspartic Acid; CHO Cells; Cricetinae; Humans; Isoleucine; Isoxazoles; Ligands; Lysine; Molecular Sequence Data; Mutagenesis; Protein Structure, Secondary; Protein Structure, Tertiary; Radioligand Assay; Receptors, Adrenergic, beta-1; Terbutaline; Valine

2006