bromisovalum has been researched along with urea in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (91.67) | 18.7374 |
| 1990's | 2 (3.33) | 18.2507 |
| 2000's | 2 (3.33) | 29.6817 |
| 2010's | 1 (1.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Kuschinsky, G | 1 |
| Böttcher, D; Hasler, K; Mair, D | 1 |
| Strubelt, O | 1 |
| Hey, D; Lasch, HG; Neuhof, H; Sablofski, I; Wilhelmi, J | 1 |
| Schwabe, U | 1 |
| Bender, G; Höbel, M | 1 |
| Poser, W | 1 |
| Butte, W; Wronski, R | 1 |
| Böttcher, D; Mittermayer, Ch | 1 |
| Iven, H; Schütt, A; Siegers, CP; Strubelt, O | 1 |
| Käferstein, H; Sticht, G | 1 |
| Bruhns, R; Dotzauer, G; Käferstein, H; Sticht, G | 1 |
| Eichelbaum, M; Sonntag, B; von Unruh, G | 1 |
| Eichelbaum, M | 1 |
| Berndt, V; Blank, HJ; Brinkmann, OH | 1 |
| Pomränke, K; Schmidt, C; Wichert, P; Wiegers, U | 1 |
| Matasovic, A; Niederwieser, A; Steinmann, B | 1 |
| Klingenfuss, B; Müller-Oerlinghausen, B; Poser, S; Poser, W | 1 |
| Dogterom, P; Mulder, GJ; Nagelkerke, JF | 1 |
| Kuipers, F; Mulder, GJ; Polhuijs, M; Vonk, RJ | 1 |
| Breimer, DD; Mulder, GJ; Schipper, C; te Koppele, JM | 1 |
| Fukuda, H; Hirose, S; Kageyama, Y; Komatsuzaki, O; Nakayama, S; Terashi, K; Yamauchi, H | 1 |
| Cockaerts, P | 1 |
| Brussee, J; Esajas, SW; Mulder, GJ; te Koppele, JM; van der Gen, A | 1 |
| Mulder, GJ; te Koppele, JM; van der Mark, EJ | 1 |
| Coles, B; Ketterer, B; Mulder, GJ; Te Koppele, JM | 1 |
| Chikasue, F; Kojima, T; Miyazaki, T; Ohtani, M; Yashiki, M | 1 |
| Asano, Y; Chiba, T; Fukatsu, R; Kurokawa, Y; Takasaka, Y; Yamashita, I | 1 |
| de Lannoy, IA; Mulder, GJ; Pang, KS; te Koppele, JM | 1 |
| Brussee, J; Mulder, GJ; Olde Boerrigter, JC; te Koppele, JM; van der Gen, A; van der Greef, J; van der Mark, EJ | 1 |
| Dogterom, P; Meijer, DK; Mulder, GJ; te Koppele, JM; van der Gen, A; Vermeulen, NP | 1 |
| ten Berg, JL | 1 |
| Sangster, B; van Dijk, A | 1 |
| Hekster, RE; Tavy, DL; Van Balkom, AJ; Van de Wetering, BJ; van Woerkom, TC | 1 |
| Chikasue, F; Kojima, T; Miyazaki, T; Okamoto, I; Yashiki, M | 1 |
| Kato, Y; Kiwada, H; Kojima, H | 2 |
| Kan, K; Kano, S; Satowa, S; Takeuchi, I | 1 |
| de Visser, AP; Leijnse-Ybema, HJ; Tan, KL | 1 |
| Hayashi, T; Hiiragi, M; Kigasawa, K; Maruyama, K | 2 |
| Kato, Y; Kiwada, H; Kojima, H; Niimura, H | 1 |
| Ishiguro, M; Okamoto, M; Umemura, A; Watanabe, S; Yamada, F; Yasue, T | 1 |
| Ishiguro, M; Okamoto, M; Yamada, F; Yasue, T | 1 |
| Csànky-Treels, JC; de Krom, MC; Tjoeng, MM; van Essen, EJ | 1 |
| Ishiguro, M; Okamoto, M; Umemura, A; Yamada, F | 1 |
| Kondo, T; Lin, Z; Nagano, T; Nakaya, T; Nishigami, J; Ohshima, T; Sawaguchi, T; Takayasu, T | 1 |
| Mulder, GJ; Ouwerkerk-Mahadevan, S; van Boom, JH | 1 |
| Ikeda, N; Kiyoshima, A; Kudo, K; Ohtsuka, Y | 1 |
| FEINBLATT, HM; FEINBLATT, TM; FERGUSON, EA | 1 |
| GERECKE, K; RICHTER, J | 2 |
| HARUNA, K | 1 |
| GIBITZ, H; HOMMA, H | 1 |
| ISHIKURA, S | 1 |
| ALHA, AR | 1 |
| CHUNDELA, B; HYNIE, I; KACL, K; SKRABANEK, P | 1 |
| Fang, CC; Wang, YT; Wu, KD; Wu, VC; Yang, SY | 1 |
1 review(s) available for bromisovalum and urea
| Article | Year |
|---|---|
[Pharmacology of hypnotics].
Topics: Barbiturates; Benzodiazepines; Bromisovalum; Chloral Hydrate; Half-Life; Humans; Hypnotics and Sedatives; Methaqualone; Piperidones; Sleep; Substance-Related Disorders; Tryptophan; Urea | 1976 |
59 other study(ies) available for bromisovalum and urea
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[Thrombocyte function in bromcarbamide poisoning].
Topics: Adult; Animals; Blood Coagulation Disorders; Blood Platelets; Bromisovalum; Female; Humans; Poisoning; Rabbits; Urea | 1975 |
[Cardiotoxicity of bromoureides].
Topics: Bromisovalum; Heart; Humans; Urea | 1977 |
The activation of intravascular coagulation by bromocarbamide.
Topics: Adult; Animals; Blood; Blood Coagulation; Bromisovalum; Disseminated Intravascular Coagulation; Female; Humans; Hydrogen-Ion Concentration; Hypoxia; Male; Pentobarbital; Rabbits; Shock; Urea | 1977 |
[1,000 deaths a year caused by nonprescription bromocarbamide-containing sleeping pills in the Federal Republic of Germany].
Topics: Bromisovalum; Germany, West; Humans; Hypnotics and Sedatives; Nonprescription Drugs; Poisoning; Substance-Related Disorders; Suicide; Urea | 1977 |
Separation and quantitative determination of acecarbromal, carbromal, and bromisoval as well as their main metabolites by means of high-pressure liquid chromatographic analysis.
Topics: Bromisovalum; Chromatography, High Pressure Liquid; Humans; Hypnotics and Sedatives; Suicide; Urea | 1977 |
[Pharmacokinetics and -dynamics of bromoureides].
Topics: Bromisovalum; Humans; Urea | 1977 |
[Diagnosis of bromoureide poisoning].
Topics: Acute Disease; Bromisovalum; Chronic Disease; Humans; Intestinal Absorption; Substance-Related Disorders; Time Factors; Urea | 1977 |
[Liver coma in bromcarbamide poisoning].
Topics: Adult; Bromisovalum; Hepatic Encephalopathy; Humans; Liver; Male; Poisoning; Suicide; Urea | 1977 |
[Comparison of the cardiotoxic effects of carbromal, bromisoval and pentobarbital].
Topics: Animals; Blood Pressure; Bromisovalum; Cardiac Output; Cats; Female; Guinea Pigs; Heart; Heart Rate; Male; Myocardial Contraction; Pentobarbital; Rats; Urea | 1978 |
[Post mortem determination of bromureides (author's transl)].
Topics: Brain Chemistry; Bromine; Bromisovalum; Cadaver; Forensic Medicine; Humans; Kidney; Muscles; Poisoning; Urea | 1978 |
[Pharmacokinetic studies in monkeys after oral and intravenous administration of bromides and bromine-containing metabolites].
Topics: Administration, Oral; Animals; Bromisovalum; Female; Half-Life; Haplorhini; Hydroxylation; Injections, Intravenous; Macaca mulatta; Male; Structure-Activity Relationship; Urea | 1978 |
Determination of monoureides in biological fluids by high-pressure-liquid-chromatography.
Topics: Bromisovalum; Chromatography, High Pressure Liquid; Methaqualone; Methods; Time Factors; Urea | 1978 |
Determination of monoureides in biological fluids by high-pressure-liquid-chromatography.
Topics: Bromisovalum; Chromatography, High Pressure Liquid; Humans; Methaqualone; Urea | 1979 |
[Differential therapy of bromcarbamide poisoning with reference to primary detoxication by means of gastro- or duodenotomy].
Topics: Adolescent; Adult; Bromisovalum; Diuretics; Duodenum; Female; Gastric Lavage; Hemoperfusion; Humans; Male; Renal Dialysis; Stomach; Urea | 1978 |
Incorporation of radioactive labelled cholin and palmitate into lung lecithin of rabbits treated with high doses of bromcarbamides, barbiturates and diazepam.
Topics: Animals; Barbiturates; Bromisovalum; Choline; Diazepam; DNA; Female; Lung; Male; Palmitates; Palmitic Acids; Pulmonary Surfactants; Rabbits; Urea | 1977 |
New bromisoval (bromural) metabolites in human urine: alpha-(cystein-S-yl)isovalerylurea, alpha-(N-acetylcystein-S-yl)isovalerylurea and alpha-(cysteamin-S-yl)isovaleric acid.
Topics: Adult; Bromisovalum; Female; Humans; Mass Spectrometry; Urea | 1978 |
[Significance of the chronic abuse of bromoureide containing hypnotics. Simple chemical methods for its detection (author's transl)].
Topics: Bromates; Bromides; Bromine; Bromisovalum; Female; Half-Life; Humans; Hypnotics and Sedatives; Indicators and Reagents; Male; Mass Screening; Photometry; Poisoning; Saliva; Substance Withdrawal Syndrome; Substance-Related Disorders; Suicide, Attempted; Urea | 1975 |
Lipid peroxidation-dependent and -independent protein thiol modifications in isolated rat hepatocytes: differential effects of vitamin E and disulfiram.
Topics: 1-Propanol; Animals; Bromisovalum; Cell Survival; Cells, Cultured; Disulfiram; Dithiothreitol; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Liver; Male; Maleates; Propanols; Proteins; Rats; Sulfhydryl Compounds; Urea; Vitamin E | 1989 |
Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats.
Topics: Animals; Bile; Bromisovalum; Glutathione; Glutathione Transferase; Jaundice; Liver; Male; Rats; Rats, Inbred Strains; Stereoisomerism; Urea | 1989 |
Stereoselectivity in the urinary excretion of the mercapturates of (R-) and (S-) alpha-bromoisovalerylurea in man.
Topics: Acetylcysteine; Adult; Bromisovalum; Chromatography, High Pressure Liquid; Glutathione; Half-Life; Humans; Male; Saliva; Stereoisomerism; Urea | 1989 |
[A case of bromovalerylurea intoxication associated with acute hepatitis and pancreatitis].
Topics: Acute Disease; Adult; Bromisovalum; Chemical and Drug Induced Liver Injury; Humans; Male; Pancreatitis; Urea | 1989 |
[Analysis of Perdolan tablets using high pressure liquid chromatography].
Topics: Acetaminophen; Analgesics; Aspirin; Bromisovalum; Caffeine; Chromatography, High Pressure Liquid; Codeine; Drug Combinations; Pharmaceutical Vehicles; Urea | 1985 |
Stereoselective glutathione conjugation of the separate alpha-bromoisovalerylurea and alpha-bromoisovaleric acid enantiomers in the rat in vivo and in rat liver subcellular fractions.
Topics: Animals; Bile; Bromisovalum; Chromatography, Gas; Glutathione; Half-Life; Liver; Molecular Conformation; Rats; Stereoisomerism; Subcellular Fractions; Urea | 1988 |
Liquid chromatographic determination of diastereomeric glutathione conjugates and further derivatives of alpha-bromoisovalerylurea in rat bile and urine by electrochemically generated bromine.
Topics: Animals; Bile; Bromine; Bromisovalum; Chromatography, High Pressure Liquid; Electrochemistry; Glutathione; Glutathione Transferase; Hydrogen-Ion Concentration; Indicators and Reagents; Liver; Male; Rats; Rats, Inbred Strains; Stereoisomerism; Subcellular Fractions; Urea | 1988 |
Stereoselectivity of rat liver glutathione transferase isoenzymes for alpha-bromoisovaleric acid and alpha-bromoisovalerylurea enantiomers.
Topics: Animals; Bromisovalum; Chromatography, High Pressure Liquid; Glutathione Transferase; In Vitro Techniques; Isoenzymes; Kinetics; Liver; Macromolecular Substances; Models, Biological; Molecular Conformation; Pentanoic Acids; Rats; Stereoisomerism; Substrate Specificity; Urea; Valerates | 1988 |
[Detection of bromovalerylurea in biological fluids by chemical ionization-selected ion monitoring--a case of bromovalerylurea intoxication].
Topics: Body Fluids; Bromisovalum; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Urea | 1987 |
Three cases of chronic bromisoval intoxication: clinical symptoms and application of energy dispersive X-ray analysis (EDX) to detect bromine in serum, urine and cerebrospinal fluid.
Topics: Adult; Bromisovalum; Electron Probe Microanalysis; Female; Humans; Spectrum Analysis; Substance-Related Disorders; Urea; X-Rays | 1987 |
Stereoselective glutathione conjugation and amidase-catalyzed hydrolysis of alpha-bromoisovalerylurea enantiomers in isolated rat hepatocytes.
Topics: Amidohydrolases; Animals; Bromisovalum; Cells, Cultured; Glutathione; Hydrolysis; Isomerism; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Urea | 1987 |
alpha-Bromoisovalerylurea as model substrate for studies on pharmacokinetics of glutathione conjugation in the rat. I. (Bio-) synthesis, analysis and identification of diastereomeric glutathione conjugates and mercapturates.
Topics: Acetylcysteine; Animals; Bile; Bromisovalum; Chromatography, High Pressure Liquid; Cysteine; Cytosol; Glutathione; Kinetics; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Rats; Stereoisomerism; Urea | 1986 |
alpha-Bromoisovalerylurea as model substrate for studies on pharmacokinetics of glutathione conjugation in the rat. II. Pharmacokinetics and stereoselectivity of metabolism and excretion in vivo and in the perfused liver.
Topics: Animals; Bromisovalum; Chromatography, Gas; Chromatography, Thin Layer; Glutathione; Half-Life; Kinetics; Liver; Mathematics; Perfusion; Rats; Stereoisomerism; Substrate Specificity; Urea | 1986 |
[Visit of an old friend, paranoid psychosis in chronic bromide poisoning].
Topics: Bromisovalum; Chronic Disease; Female; Humans; Middle Aged; Paranoid Disorders; Self Medication; Urea | 1985 |
[The question behind the question].
Topics: Adult; Bromides; Bromisovalum; Female; Humans; Substance-Related Disorders; Suicide, Attempted; Urea | 1985 |
Cerebellar atrophy due to chronic bromisovalum abuse demonstrated by computed tomography.
Topics: Adult; Atrophy; Bromisovalum; Cerebellar Diseases; Cerebellum; Female; Humans; Middle Aged; Psychoses, Substance-Induced; Substance-Related Disorders; Tomography, X-Ray Computed; Urea | 1985 |
[Chronic bromide poisoning].
Topics: Adult; Bromisovalum; Chronic Disease; Humans; Male; Self Medication; Urea | 1985 |
[Extrelut column extraction for screening of drugs in biological materials by gas chromatography and gas chromatography-mass spectrometry--a fatal poisoning by ingestion of a drug containing acetaminophen, ethenzamide and bromvalerylurea].
Topics: Acetaminophen; Adult; Bromisovalum; Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Humans; Salicylamides; Stomach; Suicide; Urea | 1985 |
Correlations between in vivo and in vitro dissolution rates of (alpha-bromoisovaleryl)urea polymorphs.
Topics: Animals; Bromisovalum; In Vitro Techniques; Kinetics; Leukocytes; Male; Rats; Rats, Inbred Strains; Solubility; Urea | 1984 |
[Three cases of bromide intoxication associated with unusual apparent hyperchloremia induced by long term abuse of Sedes A tablets].
Topics: Adult; Bromine; Bromisovalum; Chlorides; Female; Humans; Male; Middle Aged; Substance-Related Disorders; Tablets; Urea | 1984 |
["A visit from an old friend"; paranoid psychosis in chronic bromide poisoning].
Topics: Adult; Bromides; Bromisovalum; Drug Combinations; Female; Humans; Paranoid Disorders; Plant Extracts; Psychoses, Substance-Induced; Urea | 1984 |
Pharmacokinetic study on the polymorphs of (alpha-bromoisovaleryl)urea in the rat.
Topics: Animals; Biological Availability; Bromisovalum; Kinetics; Male; Rats; Rats, Inbred Strains; Urea | 1983 |
[Biopharmaceutical studies of drugs (6). Effect of 2-bromo-isovalerylurea on serum concentrations of O-ethoxybenzamide and N-(beta-hydroxybutyryl)-p-phenetidine in rabbits].
Topics: Aminophenols; Animals; Bromisovalum; Drug Interactions; Phenetidine; Rabbits; Salicylamides; Urea | 1983 |
[Biopharmaceutical studies of drugs (7). Inhibitory effect of urea derivatives on de-ethylation of O-ethoxybenzamide and N-(beta-hydroxybutyryl)-p-phenetidine].
Topics: Aminophenols; Animals; Bromisovalum; Depression, Chemical; In Vitro Techniques; Liver; Phenetidine; Rabbits; Salicylamides; Urea | 1983 |
The determination of (alpha-bromoisovaleryl)urea in plasma and the bioavailabilities of its polymorphic forms in the rat.
Topics: Animals; Biological Availability; Bromisovalum; Isomerism; Male; Rats; Rats, Inbred Strains; Urea | 1982 |
Efficacy of hemoperfusion in the therapy of bromvalerylurea (bromural) intoxication.
Topics: Adolescent; Animals; Bromisovalum; Charcoal; Dogs; Female; Hemoperfusion; Humans; Metabolic Clearance Rate; Urea | 1982 |
High-performance liquid chromatographic determination of bromural in serum upon hemoperfusion.
Topics: Animals; Bromisovalum; Chromatography, High Pressure Liquid; Dogs; Female; Hemoperfusion; Humans; Substance-Related Disorders; Urea | 1981 |
An acute bromisoval intoxication.
Topics: Adult; Bromisovalum; Furosemide; Humans; Male; Suicide, Attempted; Urea | 1980 |
[Determination of bromvalerylurea in serum by high speed liquid chromatography (author's transl)].
Topics: Animals; Bromisovalum; Chromatography, High Pressure Liquid; Dogs; Urea | 1980 |
[A fatal case due to intoxication with seven drugs detected by GC-MS and TDx methods].
Topics: Acetaminophen; Adult; Bromisovalum; Caffeine; Drug Overdose; Female; Fluorescent Antibody Technique; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; Salicylamides; Suicide; Urea | 1993 |
Isoenzyme-selective inhibition of glutathione conjugation in vivo: selective inhibition of the conjugation of S-2-Bromoisovalerylurea in the rat.
Topics: Animals; Bromisovalum; Glutathione; Glutathione Transferase; Isoenzymes; Liver; Male; Rats; Rats, Wistar; Time Factors; Urea; Urination | 1996 |
Simultaneous determination of bromvalerylurea and allylisopropylacetylurea in human blood and urine by gas chromatography-mass spectrometry.
Topics: Bromisovalum; Calibration; Gas Chromatography-Mass Spectrometry; Humans; Reference Standards; Urea | 2003 |
Acetylcarbromal and bromisovalum in combination.
Topics: Bromides; Bromisovalum; Humans; Urea | 1958 |
[Proposals for DAB 7. 12. Bromisoval].
Topics: Brevibacterium; Bromisovalum; Urea | 1960 |
[Proposals for DAB 7. 12. Bromisovalum].
Topics: Brevibacterium; Bromisovalum; Urea | 1960 |
Fate of some sedatives in the animal body. I. alpha-Bromoisovalerylurea (Bromural).
Topics: Animals; Brevibacterium; Bromisovalum; Hypnotics and Sedatives; Urea | 1961 |
[A case of fatal bromural poisoning].
Topics: Bromisovalum; Humans; Urea | 1959 |
[Analysis of foreign substances in biological material. I. Determination of bromisovalum (2-bromo-3-methylbutyryl)urea) in blood plasma or urine by polarography].
Topics: Bromides; Bromisovalum; Humans; Plasma; Polarography; Urea | 1962 |
Debromination compounds of bromisoval and carbromal in poisoning.
Topics: Bromides; Bromisovalum; Hypnotics and Sedatives; Urea | 1963 |
[ISOLATION AND DEMONSTRATION OF BROMURAL IN TOXICOLOGY].
Topics: Bromides; Bromisovalum; Chromatography; Humans; Liver; Stomach; Toxicology; Urea; Urine | 1963 |
Pseudohyperchloraemia due to bromvalerylurea abuse.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Aged; Bromides; Bromisovalum; Chlorides; Humans; Hypnotics and Sedatives; Male; Urea | 2005 |