biotin has been researched along with leucine in 49 studies
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (leucine) | Trials (leucine) | Recent Studies (post-2010) (leucine) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 28,515 | 744 | 4,178 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (53.06) | 18.7374 |
| 1990's | 8 (16.33) | 18.2507 |
| 2000's | 10 (20.41) | 29.6817 |
| 2010's | 5 (10.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernstein, IA; Mitra, RS | 1 |
| Frasch, W; Junker, A; Lehnert, W; Niederhoff, H; Saule, H | 1 |
| Pai, CH | 1 |
| Bates, SP; Hull, D; Nyhan, WL; Sweetman, L | 1 |
| Routman, S; Taylor, BL; Utter, MF | 1 |
| Mock, DM; Mock, NI | 1 |
| Ballard, FJ; Chandler, CS | 2 |
| Kinzenbaw, D; Sivesind, C; Spector, R | 1 |
| Isselbacher, KJ; Tanaka, K | 1 |
| Draffan, GH; Gompertz, D; Hull, D; Watts, JL | 1 |
| Guchhait, RB; Lane, MD; Polakis, SE | 1 |
| Axén, R; Vretblad, P | 1 |
| Bhagavan, HN; Coursin, DB | 1 |
| Gompertz, D | 1 |
| Bartlett, K; Gompertz, D; Goodey, PA | 1 |
| Chatrath, MS; Gupta, JP | 1 |
| Bartlett, K; Blair, D; Gompertz, D; Stern, CM | 1 |
| Kaneda, T | 1 |
| Nakanishi, S; Numa, S | 1 |
| Eldjarn, L; Jellum, E; Pande, H; Stokke, O; Waaler, PE | 1 |
| Cazzulo, JJ; Kornberg, HL; Sundaram, TK | 1 |
| Freytag, SO; Utter, MF | 1 |
| Desai, AJ; Desai, JD; Patel, HC | 1 |
| Lehnert, W; Niederhoff, H; Saule, H | 1 |
| Bartlett, K; Clayton, B; Hyde, J; Leonard, JV; Seakins, JW; Wilson, J | 1 |
| Edbladh, M; Edström, A; Ekström, PA | 1 |
| Kobayashi, H; Moniwa, N; Ohi, H; Shinohara, H; Sugimura, M; Terao, T | 1 |
| Beck, JE; Warr, WB | 1 |
| Beckius, GE; Bishop, DC; Kuwada, S; Oliver, DL | 1 |
| Alipour, M; Chen, Y; Jürgens, U | 1 |
| An, X; Bandler, R; Ongür, D; Price, JL | 1 |
| An, X; Ongür, D; Price, JL | 1 |
| Che, P; Nikolau, BJ; Wurtele, ES | 1 |
| Carnell, N; Henrich, CL; Mock, DM; Mock, NI | 1 |
| Nikolau, BJ; Ohlrogge, JB; Wurtele, ES | 1 |
| Iyer, LK; Kessler, BM; Kocks, C; Lennon-Dumenil, AM; Maehr, R; Overkleeft, HS; Ploegh, HL; Wang, EW | 1 |
| CARLSON, WW; ROSANO, CL; STARNES, WR; WHITESIDE-CARLSON, V | 1 |
| Aggelidou, E; Demetriades, C; Hadzopoulou-Cladaras, M; Iordanidou, P | 1 |
| de Wit, PJ; Jones, JD; Joosten, MH; Rooney, HC; van der Hoorn, RA; Van't Klooster, JW | 1 |
| Gnau, V; Höschle, B; Jendrossek, D | 1 |
| Holstege, G; Klop, EM; Mouton, LJ | 1 |
| Liu, J; Sun, Y; Uzawa, H; Xiang, X; Ye, H; Zeng, X; Zhou, B | 1 |
| Bhuniya, S; Kim, BH; Seo, YJ | 1 |
| Baugh, L; Cerutti, DS; Gülich, S; Le Trong, I; Lybrand, TP; Stayton, PS; Stenkamp, RE | 1 |
| Bogusiewicz, A; Boysen, G; Dawson, AM; Henrich, CL; Horvath, TD; Matthews, NI; Mock, DM; Moran, JH; Owen, SN; Spencer, HJ; Stratton, SL | 1 |
| Ilyas, M; Ilyas, S; Mathur, S; van der Hoorn, RA | 1 |
| Caudill, MA; Gayle, A; Jiang, X; Lucas, LK; Malysheva, O; Perry, CA; West, AA; Yan, J | 1 |
| Djukovic, D; Gu, H; O'Keefe, GE; Parent, BA; Raftery, D; Seaton, M; Sood, RF | 1 |
2 review(s) available for biotin and leucine
| Article | Year |
|---|---|
Inborn errors of organic acid metabolism.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Biotin; Carboxylic Acids; Chromatography, Gas; Coenzyme A; Crotonates; Female; Gestational Age; Humans; Hydroxy Acids; Hydroxybutyrates; Infant; Infant, Newborn; Isomerases; Leucine; Male; Malonates; Metabolism, Inborn Errors; Pedigree; Pregnancy; Prenatal Diagnosis; Propionates; Pyrrolidonecarboxylic Acid; Valerates; Vitamin B 12 | 1974 |
Plant biotin-containing carboxylases.
Topics: Acetyl-CoA Carboxylase; Biotin; Carbon-Carbon Ligases; Carbon-Nitrogen Ligases; Gene Expression Regulation, Enzymologic; Leucine; Models, Biological; Models, Chemical; Plant Physiological Phenomena; Protein Conformation; RNA, Messenger; Substrate Specificity | 2003 |
1 trial(s) available for biotin and leucine
| Article | Year |
|---|---|
Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
Topics: Adult; Biomarkers; Biotin; Carbon-Carbon Ligases; Carnitine; Choline; Chromatography, Liquid; Diet; Dietary Supplements; Female; Humans; Lactation; Leucine; Milk, Human; New York; Patient Compliance; Pregnancy; Tandem Mass Spectrometry; Valerates; Young Adult | 2014 |
46 other study(ies) available for biotin and leucine
| Article | Year |
|---|---|
Nature of the repair process associated with the recovery of Escherichia coli after exposure to Cd2+.
Topics: Biotin; Cadmium; Cell Division; DNA Repair; Escherichia coli; Leucine; Methionine; Species Specificity; Temperature; Thymine | 1977 |
A case of biotin-responsive 3-methylcrotonylglycin- and 3-hydroxyisovaleric aciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Biotin; Female; Humans; Infant; Leucine; Muscle Hypotonia; Seizures | 1979 |
Genetics of biotin biosynthesis in Bacillus subtilis.
Topics: Arginine; Bacillus subtilis; Biotin; Chromatography; Chromosome Mapping; Crosses, Genetic; Drug Resistance, Microbial; Escherichia coli; Genes; Leucine; Microbial Sensitivity Tests; Mitomycins; Mutation; Pimelic Acids; Transduction, Genetic; Transformation, Genetic | 1975 |
Propionyl-CoA carboxylase deficiency in a patient with biotin-responsive 3-methylcrotonylglycinuria.
Topics: Biotin; Carboxy-Lyases; Citrates; Creatinine; Crotonates; Fibroblasts; Glycine; Humans; Infant; Leucine; Male; Propionates; Renal Aminoacidurias | 1977 |
The control of the synthesis of pyruvate carboxylase in Pseudomonas citronellolis. Evience from double labeling studies.
Topics: Aspartic Acid; Bacterial Proteins; Biotin; Carbon Radioisotopes; Culture Media; Glucose; Lactates; Leucine; Malates; Peptide Biosynthesis; Pseudomonas; Pyruvate Carboxylase; Tritium | 1975 |
Biotin deficiency in rats: disturbances of leucine metabolism are detectable early.
Topics: Animals; Biotin; Gas Chromatography-Mass Spectrometry; Leucine; Male; Rats; Rats, Inbred Strains; Valerates | 1992 |
Distribution and degradation of biotin-containing carboxylases in human cell lines.
Topics: Acetyl-CoA Carboxylase; Biotin; Carbon-Carbon Ligases; Carboxy-Lyases; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Leucine; Ligases; Methylmalonyl-CoA Decarboxylase; Mitochondria; Proteins; Pyruvate Carboxylase | 1985 |
Regulation of the breakdown rates of biotin-containing proteins in Swiss 3T3-L1 cells.
Topics: Adenine; Biotin; Cell Line; Electrophoresis, Polyacrylamide Gel; Insulin; Leucine; Leupeptins; Proteins | 1988 |
Pantothenic acid transport through the blood-brain barrier.
Topics: Animals; Biological Transport; Biotin; Blood-Brain Barrier; Brain; Capillaries; Capillary Permeability; Fatty Acids; Kinetics; Leucine; Pantothenic Acid; Probenecid; Rats; Rats, Inbred Strains | 1986 |
Experimental beta-hydroxyisovaleric aciduria induced by biotin deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Avitaminosis; Biotin; Butyrates; Carbon Isotopes; Leucine; Rats | 1970 |
Biotin-responsive beta-methylcrotonylglycinuria.
Topics: Acidosis; Administration, Oral; Amino Acid Metabolism, Inborn Errors; Biotin; Butyrates; Carbon Dioxide; Carboxy-Lyases; Chromatography, Gas; Fatty Acids; Glycine; Humans; Infant; Leucine; Male; Partial Pressure; Valerates; Valine; Vomiting | 1971 |
Stringent control of fatty acid synthesis in Escherichia coli. Possible regulation of acetyl coenzyme A carboxylase by ppGpp.
Topics: Acetates; Acetyl-CoA Carboxylase; Biotin; Carbon Radioisotopes; Carboxy-Lyases; Cardiolipins; Culture Media; Escherichia coli; Fatty Acids; Glucose; Guanine Nucleotides; Kinetics; Leucine; Ligases; Lipid Metabolism; Lipids; Manganese; Phosphatidylethanolamines; Phospholipids; Species Specificity; Tritium | 1973 |
The use of isocyanides for the immobilization of biological molecules.
Topics: Acrylamides; Adenosine Monophosphate; Biotin; Chromatography, Gel; Chymotrypsin; Cyanides; Esters; Humans; Hydrogen-Ion Concentration; Leucine; Methods; Molecular Weight; NAD; Penicillanic Acid; Penicillin G; Phenylalanine; Protein Binding; RNA; Serum Albumin; Temperature; Tyrosine | 1973 |
Nucleic acid and protein contents, and incorporation of L-[U-14C] leucine into proteins of brain and liver in biotin-deficient rats.
Topics: Animals; Biotin; Brain; Carbon Radioisotopes; Cell Count; DNA; Leucine; Liver; Male; Protein Biosynthesis; Rats; RNA; Vitamin B Deficiency | 1974 |
Evidence for the enzymic defect in beta-methylcrotonylglycinuria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Biotin; Carbon Isotopes; Child, Preschool; Coenzyme A; Crotonates; Glycine; Humans; Infant, Newborn; Leucine; Leukocytes; Ligases | 1973 |
Radiation induced biochemical mutation in Colletotrichum gloeosporioides penz. causing anthracnose of guava (Psidium guajava L).
Topics: Biotin; Cobalt Radioisotopes; Cystine; Leucine; Methionine; Mitosporic Fungi; Mutation; Phosphorus Radioisotopes; Plant Diseases; Plants; Radiation Effects; Thiamine | 1973 |
Child with a defect in leucine metabolism associated with beta-hydroxyisovaleric aciduria and beta-methylcrotonylglycinuria.
Topics: Amino Acid Metabolism, Inborn Errors; Biotin; Creatinine; Crotonates; Glycine; Humans; Infant; Leucine; Male; Pentanols; Pneumonia; Valerates | 1973 |
Biosynthesis of branched-chain fatty acids. IV. Factors affecting relative abundance of fatty acids produced by Bacillus subtilis.
Topics: Asparagine; Bacillus subtilis; Biotin; Chromatography, Gas; Culture Media; Fatty Acids; Isoleucine; Leucine; Valine | 1966 |
Purification of rat liver acetyl coenzyme A carboxylase and immunochemical studies on its synthesis and degradation.
Topics: Animals; Antibodies; Biotin; Carbon Isotopes; Centrifugation, Density Gradient; Chickens; Chromatography, Gel; Coenzyme A; Diabetes Mellitus, Experimental; Diet; Fasting; Female; Immunodiffusion; Leucine; Ligases; Liver; Male; Precipitin Tests; Rabbits; Rats; Time Factors; Tritium; Ultracentrifugation | 1970 |
Beta-methylcrotonyl-CoA carboxylase deficiency: a new metabolic error in leucine degradation.
Topics: Amino Acid Metabolism, Inborn Errors; Biotin; Bronchopneumonia; Butyrates; Carbon Dioxide; Carbon-Carbon Ligases; Chromatography, Gas; Diet Therapy; Female; Glycine; Humans; Infant; Leucine; Ligases; Mass Spectrometry; Neurologic Manifestations; Odorants; Pentanols; Valerates | 1972 |
Regulation of pyruvate carboxylase formation from the apo-enzyme and biotin in a thermophilic bacillus.
Topics: Bacillus; Biotin; Carbon Isotopes; Coenzyme A; Culture Media; Enzyme Induction; Hot Temperature; Leucine; Ligases; Pyruvates | 1969 |
Regulation of the synthesis and degradation of pyruvate carboxylase in 3T3-L1 cells.
Topics: Animals; Apoenzymes; Avidin; Biotin; Cell Differentiation; Cell Line; Enzyme Induction; Immune Sera; Immunosorbent Techniques; Leucine; Mice; Pyruvate Carboxylase; Rats | 1983 |
Effect of biotin on alkaloid production during submerged cultivation of Claviceps sp. strain SD-58.
Topics: Alkaloids; Avidin; Biotin; Claviceps; Culture Media; Kinetics; Leucine | 1983 |
[Convulsions in an infant with biotin-dependent 3-methylcrotonylglycinuria].
Topics: Amino Acid Metabolism, Inborn Errors; Biotin; Female; Humans; Infant; Leucine; Seizures | 1980 |
Inherited disorders of 3-methylcrotonyl CoA carboxylation.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Biotin; Carbon-Carbon Ligases; Central Nervous System Diseases; Female; Humans; Infant; Infant, Newborn; Leucine; Ligases | 1981 |
Time-dependent effects of insulin on Schwann cell proliferation in the in vitro regenerating adult frog sciatic nerve.
Topics: Animals; Biotin; Cell Division; In Vitro Techniques; Insulin; Leucine; Nerve Crush; Nerve Regeneration; Rana temporaria; Schwann Cells; Sciatic Nerve; Thymidine; Time Factors | 1993 |
Effects of membrane-associated cathepsin B on the activation of receptor-bound prourokinase and subsequent invasion of reconstituted basement membranes.
Topics: Basement Membrane; Biotin; Cathepsin B; Cell Line; Cell Membrane; Collagen; Cysteine Proteinase Inhibitors; Drug Combinations; Enzyme Activation; Humans; Laminin; Leucine; Proteoglycans; Recombinant Proteins; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1993 |
Multiple projections from the ventral nucleus of the trapezoid body in the rat.
Topics: Animals; Auditory Pathways; Biotin; Cochlear Nucleus; Dextrans; Fluorescent Dyes; Inferior Colliculi; Iontophoresis; Leucine; Male; Olivary Nucleus; Pons; Rats; Rats, Sprague-Dawley; Statistics as Topic; Tritium | 1996 |
Simultaneous anterograde labeling of axonal layers from lateral superior olive and dorsal cochlear nucleus in the inferior colliculus of cat.
Topics: Afferent Pathways; Animals; Axonal Transport; Axons; Biotin; Cats; Cochlear Nucleus; Fluorescein; Fluoresceins; Functional Laterality; Inferior Colliculi; Leucine; Models, Neurological; Olivary Nucleus; Rhodamines; Tritium; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 1997 |
Anterograde projections of the cortical tongue area of the tree shrew (Tupaia belangeri).
Topics: Animals; Axonal Transport; Biotin; Brain; Cerebral Cortex; Dextrans; Fluorescent Dyes; Leucine; Motor Cortex; Nerve Fibers; Phytohemagglutinins; Primates; Tupaia | 1997 |
Prefrontal cortical projections to longitudinal columns in the midbrain periaqueductal gray in macaque monkeys.
Topics: Amidines; Amygdala; Animals; Autonomic Nervous System; Biotin; Cholera Toxin; Dextrans; Emotions; Female; Fluorescent Dyes; Gyrus Cinguli; Leucine; Macaca fascicularis; Macaca nemestrina; Male; Neural Pathways; Neurons, Afferent; Periaqueductal Gray; Prefrontal Cortex; Rhodamines; Temporal Lobe; Tritium | 1998 |
Prefrontal cortical projections to the hypothalamus in macaque monkeys.
Topics: Amidines; Amygdala; Animals; Autonomic Nervous System; Behavior, Animal; Biotin; Dextrans; Feeding Behavior; Female; Fluorescent Dyes; Hypothalamus; Leucine; Macaca fascicularis; Male; Motor Neurons; Neural Pathways; Prefrontal Cortex; Rhodamines; Substantia Nigra; Tritium | 1998 |
Metabolic and environmental regulation of 3-methylcrotonyl-coenzyme A carboxylase expression in Arabidopsis.
Topics: Arabidopsis; Biotin; Butadienes; Carbohydrates; Carbon; Carbon Dioxide; Carbon-Carbon Ligases; Cell Communication; Cell Nucleus; Fructose; Galactose; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucose; Hemiterpenes; Leucine; Light; Mevalonic Acid; Mitochondria; Pentanes; Plants, Genetically Modified; Signal Transduction; Sorbitol; Sucrose | 2002 |
Indicators of marginal biotin deficiency and repletion in humans: validation of 3-hydroxyisovaleric acid excretion and a leucine challenge.
Topics: Adult; Biotin; Diet; Dose-Response Relationship, Drug; Egg White; Female; Humans; Leucine; Male; Time Factors; Valerates | 2002 |
Functional proteomics of the active cysteine protease content in Drosophila S2 cells.
Topics: Amino Acid Sequence; Animals; Biotin; Cathepsins; Cell Line; Cysteine Endopeptidases; Drosophila; Drosophila Proteins; Electrophoresis, Polyacrylamide Gel; Leucine; Lysosomes; Mice; Molecular Probes; Molecular Sequence Data; Phagocytes; Spectrometry, Mass, Electrospray Ionization | 2003 |
Non-specificity of biotin activity for leuconostoc.
Topics: Biotin; Humans; Leucine; Leuconostoc | 1951 |
Distinct amino acid residues may be involved in coactivator and ligand interactions in hepatocyte nuclear factor-4alpha.
Topics: Amino Acids; Animals; Arginine; Biotin; Cell Line; Chloramphenicol O-Acetyltransferase; COS Cells; Detergents; Dimerization; DNA-Binding Proteins; Gene Deletion; Genetic Vectors; Glutathione Transferase; Hepatocyte Nuclear Factor 4; Humans; Isoleucine; Leucine; Ligands; Methionine; Models, Biological; Mutation; Phosphoproteins; Plasmids; Point Mutation; Protein Binding; Protein Structure, Tertiary; Serine; Transcription Factors; Transcription, Genetic; Transfection | 2005 |
Cladosporium Avr2 inhibits tomato Rcr3 protease required for Cf-2-dependent disease resistance.
Topics: Biotin; Cladosporium; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Extracellular Fluid; Fungal Proteins; Hydrogen-Ion Concentration; Immunoprecipitation; Leucine; Nicotiana; Pichia; Plant Diseases; Plant Leaves; Plant Proteins; Recombinant Fusion Proteins; Solanum lycopersicum | 2005 |
Methylcrotonyl-CoA and geranyl-CoA carboxylases are involved in leucine/isovalerate utilization (Liu) and acyclic terpene utilization (Atu), and are encoded by liuB/liuD and atuC/atuF, in Pseudomonas aeruginosa.
Topics: Acyclic Monoterpenes; Bacterial Proteins; Biotin; Carbon-Carbon Ligases; Culture Media; Hemiterpenes; Leucine; Monoterpenes; Multigene Family; Pentanoic Acids; Pseudomonas aeruginosa; Terpenes | 2005 |
Periparabigeminal and adjoining mesencephalic tegmental field projections to the dorsolateral periaqueductal grey in cat - a possible role for oculomotor input in the defensive system.
Topics: Animals; Biotin; Cats; Dextrans; Eye Movements; Functional Laterality; Leucine; Neural Pathways; Periaqueductal Gray; Pons; Tegmentum Mesencephali; Tritium; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 2006 |
Effective chemoenzymatic synthesis of p-aminophenyl glycosides of sialyl N-acetyllactosaminide and analysis of their interactions with lectins.
Topics: Amino Sugars; beta-Galactosidase; Biotin; Carbohydrate Conformation; Carbohydrate Sequence; Glycosides; Lectins; Leucine; Molecular Sequence Data; Molecular Structure; Sialyltransferases; Surface Plasmon Resonance | 2007 |
Reversible sol-gel signaling system with epMB for the study of enzyme- and pH-triggered oligonucleotide release from a biotin hydrogel.
Topics: Acrylic Resins; Biotin; Chromatography, High Pressure Liquid; Fluorescence; Hydrogels; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Oligonucleotides; Pyrenes; Sepharose | 2007 |
A distal point mutation in the streptavidin-biotin complex preserves structure but diminishes binding affinity: experimental evidence of electronic polarization effects?
Topics: Binding Sites; Biotin; Electrons; Hydrogen Bonding; Leucine; Ligands; Molecular Dynamics Simulation; Phenylalanine; Point Mutation; Protein Binding; Protein Stability; Streptavidin; Thermodynamics | 2010 |
Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in marginally biotin-deficient humans.
Topics: Adult; Biotin; Carnitine; Cohort Studies; Female; Humans; Leucine; Male; Valerates | 2011 |
Selective conjugation of proteins by mining active proteomes through click-functionalized magnetic nanoparticles.
Topics: Azides; Biotin; Click Chemistry; Cysteine; Data Mining; Ferric Compounds; Leucine; Luminescence; Magnetics; Microwaves; Nanoparticles; Nanotechnology; Peptide Hydrolases; Plant Proteins; Proteome; Rhodamines; Spectroscopy, Fourier Transform Infrared; Streptavidin; Thermogravimetry | 2013 |
Use of Metabolomics to Trend Recovery and Therapy After Injury in Critically Ill Trauma Patients.
Topics: Adenosine Monophosphate; Adult; Biomarkers; Biotin; Case-Control Studies; Choline; Cytidine; Fatty Acids; Female; Humans; Injury Severity Score; Isoleucine; Leucine; Male; Metabolome; Metabolomics; Middle Aged; Muscle, Skeletal; Niacinamide; Nucleotides; Oxidative Stress; Principal Component Analysis; Prospective Studies; Serine; Time Factors; Valine; Wounds, Nonpenetrating | 2016 |