betulin has been researched along with lupane in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Dzubák, P; Fischer, PM; Hajdúch, M; Janost'áková, A; Klinot, J; Klinotová, E; Korínková, G; Krecek, V; Nosková, V; Parsons, S; Sarek, J; Thomson, JO; Wang, S; Zhelev, NZ | 1 |
| Dufour, P; Gauthier, C; Lebrun, M; Legault, J; Pichette, A | 1 |
| Bouchard, J; Dufour, P; Gauthier, C; Legault, J; Pichette, A; Thibeault, D | 1 |
| Gauthier, C; Lavoie, S; Legault, J; Pichette, A; Rondeau, S; Tremblay, S | 1 |
| Gauthier, C; Lavoie, S; Legault, J; Pichette, A; Piochon, M; Tremblay, S | 1 |
| Kalbitz, J; Kaluđerović, GN; Kommera, H; Paschke, R | 1 |
| Dzubak, P; Hajduch, M; Sarek, J; Urban, M; Vlk, M | 1 |
| Barthel, A; Csuk, R; Nitsche, C; Siewert, B; Stark, S | 1 |
| Chapuis, JC; Groy, TL; Hempenstall, F; Melody, N; Pettit, GR; Williams, L | 1 |
| Carcache de Blanco, EJ; Cassera, MB; Chai, H; Kinghorn, AD; Merino, EF; Muñoz Acuña, U; Ninh, TN; Pan, L; Park, HY; Rakotondraibe, LH; Soejarto, DD; Thanh, BV | 1 |
| Anderson, TJ; Cai, S; Cichewicz, RH; Du, L; Mooberry, SL; Nair, S; Peng, J; Powell, DR; Risinger, AL | 1 |
| Fan, P; Li, D; Lou, H; Ye, Y; Yuan, H; Zhang, T | 1 |
| Adamek, J; Grymel, M; Zawojak, M | 1 |
| Chang, IL; Chen, HY; Hsieh, CP; Huang, YF; Lin, YC | 1 |
| Alakurtti, S; Geyer, J; Glebe, D; Goldmann, N; Kirstgen, M; Lehmann, F; Lowjaga, KAAT; Müller, SF; Yli-Kauhaluoma, J | 1 |
| Bębenek, E; Borkowska, P; Boryczka, S; Chodurek, E; Chrobak, E; Jaworska-Kik, M; Kaps, A; Kasperczyk, J; Orchel, A; Paduszyński, P | 1 |
| Cummings, J; Kazakova, O; Militaru, A; Mioc, M; Ordway, DJ; Petrova, A; Racoviceanu, R; Robertson, G; Slayden, RA; Șoica, C; Udrescu, L; Udrescu, M; Voicu, A | 1 |
1 review(s) available for betulin and lupane
| Article | Year |
|---|---|
Triphenylphosphonium Analogues of Betulin and Betulinic Acid with Biological Activity: A Comprehensive Review.
Topics: Antineoplastic Agents; Betulinic Acid; Esters; Molecular Structure; Pentacyclic Triterpenes; Triterpenes | 2019 |
16 other study(ies) available for betulin and lupane
| Article | Year |
|---|---|
New lupane derived compounds with pro-apoptotic activity in cancer cells: synthesis and structure-activity relationships.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Crystallography, X-Ray; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Mice; Stereoisomerism; Structure-Activity Relationship; Triterpenes | 2003 |
Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents.
Topics: Animals; Antineoplastic Agents, Phytogenic; Betula; Betulinic Acid; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Fibroblasts; Glycosides; Humans; Mice; Pentacyclic Triterpenes; Triterpenes | 2006 |
Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3beta-O-monodesmosidic saponins starting from betulin.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Betula; Cells, Cultured; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Lung Neoplasms; Molecular Structure; Saponins; Structure-Activity Relationship; Triterpenes | 2007 |
Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins.
Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pentacyclic Triterpenes; Saponins; Structure-Activity Relationship; Triterpenes | 2009 |
Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products.
Topics: Animals; Cell Line, Tumor; Cytotoxins; Erythrocytes; Hemolytic Agents; Humans; Saponins; Sheep; Triterpenes; Tropanes | 2009 |
Lupane triterpenoids--betulin and betulinic acid derivatives induce apoptosis in tumor cells.
Topics: Antineoplastic Agents; Apoptosis; Betulinic Acid; Caspases; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Kinetics; Pentacyclic Triterpenes; Triterpenes | 2011 |
Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid.
Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Cell Line, Tumor; Crystallography, X-Ray; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2012 |
Alkylidene branched lupane derivatives: synthesis and antitumor activity.
Topics: Alkenes; Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Hydroxides; Inhibitory Concentration 50; Oxidation-Reduction; Triterpenes | 2012 |
Antineoplastic agents. 595. Structural modifications of betulin and the X-ray crystal structure of an unusual betulin amine dimer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Betula; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Mice; Molecular Structure; Structure-Activity Relationship; Triterpenes | 2014 |
New Bioactive Lupane Triterpene Coumaroyl Esters Isolated from Buxus cochinchinensis.
Topics: Alkaloids; Antimalarials; Buxus; Esters; HT29 Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Plant Extracts; Plasmodium falciparum; Triterpenes; Vietnam | 2015 |
Identification of Compounds with Efficacy against Malaria Parasites from Common North American Plants.
Topics: Animals; Antimalarials; Artemisinins; Drug Resistance; Glycosides; HeLa Cells; Humans; Malaria; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Plasmodium falciparum; Quinine; Triterpenes; United States | 2016 |
Mitochondria-Targeted Lupane Triterpenoid Derivatives and Their Selective Apoptosis-Inducing Anticancer Mechanisms.
Topics: Animals; Antineoplastic Agents; Apoptosis; Betulinic Acid; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Heterografts; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neoplasm Metastasis; Neoplasm Transplantation; Organophosphorus Compounds; Pentacyclic Triterpenes; Reactive Oxygen Species; Structure-Activity Relationship; Triterpenes; Zebrafish | 2017 |
Betulin inhibits mTOR and induces autophagy to promote apoptosis in human osteosarcoma cell lines.
Topics: Apoptosis; Autophagy; Bone Neoplasms; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Osteosarcoma; TOR Serine-Threonine Kinases; Triterpenes | 2020 |
Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids.
Topics: Bile Acids and Salts; Hep G2 Cells; Hepatitis B virus; Hepatitis Delta Virus; Humans; Organic Anion Transporters, Sodium-Dependent; Receptors, Virus; Structure-Activity Relationship; Symporters; Triterpenes; Virus Internalization | 2020 |
Anticancer Activity of the Acetylenic Derivative of Betulin Phosphate Involves Induction of Necrotic-Like Death in Breast Cancer Cells In Vitro.
Topics: Alkynes; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspases; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Humans; L-Lactate Dehydrogenase; MCF-7 Cells; Membrane Potential, Mitochondrial; Necrosis; Phosphates; Reactive Oxygen Species; Triterpenes; Up-Regulation | 2021 |
New Investigations with Lupane Type A-Ring Azepane Triterpenoids for Antimycobacterial Drug Candidate Design.
Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA-Directed RNA Polymerases; Drug Design; Drug Resistance, Bacterial; Humans; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Rifampin; Triterpenes; Tuberculosis | 2021 |