Page last updated: 2024-08-25

atipamezole and idazoxan

atipamezole has been researched along with idazoxan in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19905 (17.24)18.7374
1990's15 (51.72)18.2507
2000's6 (20.69)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agbaba, D; Azzali, E; Costantino, G; Glisic, S; Laurila, JM; Nikolic, K; Perovic, V; Pieroni, M; Radi, M; Scheinin, M; Srdic-Rajic, T; Tassini, S; Veljkovic, N; Vucicevic, J1
Biegon, A; Budinger, TF; Mathis, CA1
Durcan, MJ; Linnoila, M; Lister, RG3
Berlan, M; Galitzky, J; Montastruc, P; Tran, MA1
Durcan, MJ; Linnoila, M; Lister, RG; Nutt, DJ1
Chen, BX; Doze, VA; Maze, M1
Durcan, MJ; Linnoila, M; Lister, RG; Wozniak, KM1
Hayashi, Y; Kamibayashi, T; Mammoto, T; Sasaki, S; Takada, K; Yamatodani, A; Yoshiya, I1
Goodwin, WB; Guyenet, PG; Huangfu, D1
Halme, M; Savola, JM; Scheinin, M; Sjöholm, B1
Haapalinna, A; Riekkinen, P; Sirviö, J; Yavich, L1
Dickenson, AH; Stanfa, LC1
Colpaert, F; Marien, M; Tellez, S1
Diaz, A; Dickenson, AH; Mayet, S1
Dickenson, AH; Green, GM; Lyons, L1
Audinot, V; Chaput, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Nicolas, JP; Richard, N; Touzard, M; Verrièle, L1
Baertschi, AJ; Grubb, MC; Guyenet, PG; Pence, R; Stornetta, RL1
Heal, DJ; Stanford, SC; Wortley, KE1
Hillilä, M; Lähdesmäki, J; Pyykkö, K; Scheinin, M; Sjöholm, B1
Clarke, RW; Eves, S; Harris, J; Peachey, JE; Stuart, E1
Pauwels, PJ; Tardif, S1
Haapalinna, A; Honkanen, A; Juhila, J; Korpi, ER; Sallinen, J; Scheinin, M; Sirviö, J1
Berntsson, K; Dahlström, M; Elwing, H; Jonsson, PR; Lindgren, F; Mårtensson, LG; Sjögren, M1
Cahill, CM; Jhamandas, K; Milne, B; Sutak, M1
Bundzikova, J; Kiss, A; Mikkelsen, JD; Pirnik, Z; Zelena, D1
Galizzi, JP; Lockhart, B; Millan, MJ; Rivet, JM; Rodriguez, M; Serres, F; Sharp, T1
Arianna, M; Franco, M; Gentile, L; Luca, R; Roberta, L1

Trials

1 trial(s) available for atipamezole and idazoxan

ArticleYear
IMMOBILIZING THE VULNERABLE APENNINE CHAMOIS (RUPICAPRA PYRENAICA ORNATA) WITH A LOW-DOSE XYLAZINE-KETAMINE COMBINATION, REVERSED WITH IDAZOXAN OR ATIPAMEZOLE.
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2015, Volume: 46, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthetics, Dissociative; Animals; Animals, Wild; Animals, Zoo; Drug Therapy, Combination; Female; Hypnotics and Sedatives; Idazoxan; Imidazoles; Immobilization; Ketamine; Male; Rupicapra; Xylazine

2015

Other Studies

28 other study(ies) available for atipamezole and idazoxan

ArticleYear
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin.
    Bioorganic & medicinal chemistry, 2016, 07-15, Volume: 24, Issue:14

    Topics: Adrenergic alpha-Agonists; Antibiotics, Antineoplastic; Apoptosis; Doxorubicin; Drug Synergism; Humans; K562 Cells; Ligands; Molecular Structure; Oxazoles; Receptors, Adrenergic, alpha-2; Rilmenidine

2016
Quantitative in vitro and ex vivo autoradiography of the alpha 2-adrenoceptor antagonist [3H]atipamezole.
    European journal of pharmacology, 1992, Nov-24, Volume: 224, Issue:1

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Animals; Autoradiography; Brain; Brimonidine Tartrate; Dioxanes; Humans; Idazoxan; Imidazoles; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tissue Distribution

1992
Evidence for central alpha-2 adrenoceptors, not imidazoline binding sites, mediating the ethanol-attenuating properties of alpha-2 adrenoceptor antagonists.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Ataxia; Body Temperature; Brain; Dioxanes; Ethanol; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Mice; Motor Activity; Quinolizines; Receptors, Adrenergic, alpha; Receptors, Drug

1991
Anorectic effect of alpha 2-antagonists in dog: effect of acute and chronic treatment.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Blood Glucose; Blood Platelets; Body Weight; Catecholamines; Cell Membrane; Dioxanes; Dogs; Fatty Acids, Nonesterified; Feeding Behavior; Idazoxan; Imidazoles; Insulin; Male; Nadolol; Yohimbine

1991
Attenuation of ethanol intoxication by alpha-2 adrenoceptor antagonists.
    Life sciences, 1989, Volume: 44, Issue:2

    Topics: Adrenergic alpha-Antagonists; Alcoholic Intoxication; Animals; Azides; Behavior, Animal; Benzodiazepines; Dioxanes; Ethanol; Idazoxan; Imidazoles; Mice; Receptors, GABA-A; Seizures

1989
Interactions of alpha 2-adrenoceptor antagonists with medetomidine and with ethanol in a holeboard test.
    Neuropharmacology, 1989, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dioxanes; Ethanol; Idazoxan; Imidazoles; Male; Medetomidine; Mice

1989
Behavioral effects of alpha 2 adrenoceptor antagonists and their interactions with ethanol in tests of locomotion, exploration and anxiety in mice.
    Psychopharmacology, 1989, Volume: 97, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Anxiety; Dioxanes; Drug Interactions; Ethanol; Exploratory Behavior; Idazoxan; Imidazoles; Male; Mice; Motor Activity

1989
Dexmedetomidine produces a hypnotic-anesthetic action in rats via activation of central alpha-2 adrenoceptors.
    Anesthesiology, 1989, Volume: 71, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Anesthetics; Animals; Dioxanes; Hypnotics and Sedatives; Idazoxan; Imidazoles; Injections, Intraperitoneal; Male; Medetomidine; Muscle Relaxation; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha

1989
Attenuation of hypothermic effects of ethanol by alpha 2-adrenoceptor blockers.
    European journal of pharmacology, 1989, Aug-03, Volume: 166, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Azides; Benzodiazepines; Body Temperature; Dioxanes; Dose-Response Relationship, Drug; Ethanol; Idazoxan; Imidazoles; Male; Mice; Pentobarbital; Time Factors

1989
Further characterization of the receptor mechanism involved in the antidysrhythmic effect of dexmedetomidine on halothane/epinephrine dysrhythmias in dogs.
    Anesthesiology, 1995, Volume: 83, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dogs; Drug Interactions; Epinephrine; Female; Halothane; Hemodynamics; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Medetomidine; Receptors, Drug; Ventricular Premature Complexes

1995
Sympatholytic effect of tricyclic antidepressants: site and mechanism of action in anesthetized rats.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Baclofen; Blood Pressure; Brain Mapping; Desipramine; Dioxanes; Fluoxetine; gamma-Aminobutyric Acid; Idazoxan; Imidazoles; Male; Medulla Oblongata; Microinjections; Nordefrin; Oxidopamine; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Sympatholytics; Time Factors

1995
Recombinant human alpha 2-adrenoceptor subtypes: comparison of [3H]rauwolscine, [3H]atipamezole and [3H]RX821002 as radioligands.
    Biochimica et biophysica acta, 1995, Apr-28, Volume: 1266, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding, Competitive; Buffers; Cell Line; Dioxanes; Humans; Idazoxan; Imidazoles; Kinetics; Mice; Radioligand Assay; Recombinant Proteins; Yohimbine

1995
Some unusual effects of alpha 2-adrenergic drugs on cortical high voltage spindles in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:4

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Cerebral Cortex; Dioxanes; Dose-Response Relationship, Drug; Electrophysiology; Idazoxan; Imidazoles; Male; Rats; Rats, Wistar; Yohimbine

1994
Enhanced alpha-2 adrenergic controls and spinal morphine potency in inflammation.
    Neuroreport, 1994, Jan-12, Volume: 5, Issue:4

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Carrageenan; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Idazoxan; Imidazoles; Inflammation; Injections, Spinal; Male; Medetomidine; Morphine; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2

1994
Acetylcholine release in the rat prefrontal cortex in vivo: modulation by alpha 2-adrenoceptor agonists and antagonists.
    Journal of neurochemistry, 1997, Volume: 68, Issue:2

    Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Guanabenz; Idazoxan; Imidazoles; Male; Microdialysis; Piperoxan; Prefrontal Cortex; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley

1997
BU-224 produces spinal antinociception as an agonist at imidazoline I2 receptors.
    European journal of pharmacology, 1997, Aug-20, Volume: 333, Issue:1

    Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Dose-Response Relationship, Drug; Electrophysiology; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, Drug; Spinal Cord; Synaptic Transmission; Transcutaneous Electric Nerve Stimulation; Yohimbine

1997
Alpha2-adrenoceptor antagonists enhance responses of dorsal horn neurones to formalin induced inflammation.
    European journal of pharmacology, 1998, Apr-24, Volume: 347, Issue:2-3

    Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Formaldehyde; Idazoxan; Imidazoles; Inflammation; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine

1998
Actions of alpha2 adrenoceptor ligands at alpha2A and 5-HT1A receptors: the antagonist, atipamezole, and the agonist, dexmedetomidine, are highly selective for alpha2A adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 358, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brimonidine Tartrate; CHO Cells; Cricetinae; Guanfacine; Humans; Idazoxan; Imidazoles; Ligands; Medetomidine; Quinoxalines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Yohimbine

1998
Antagonist precipitated clonidine withdrawal in rat: effects on locus coeruleus neurons, sympathetic nerves and cardiovascular parameters.
    Journal of the autonomic nervous system, 1998, Jul-15, Volume: 71, Issue:2-3

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Cardiovascular System; Clonidine; Consciousness; Halothane; Heart Rate; Idazoxan; Imidazoles; Locus Coeruleus; Male; Neurons; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Substance Withdrawal Syndrome; Sympathetic Nervous System; Sympatholytics; Vascular Resistance

1998
Modulation of sibutramine-induced increases in extracellular noradrenaline concentration in rat frontal cortex and hypothalamus by alpha2-adrenoceptors.
    British journal of pharmacology, 1999, Volume: 128, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Cyclobutanes; Dialysis; Frontal Lobe; Hypothalamus; Idazoxan; Imidazoles; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2

1999
Non-adrenergic binding of [3H]atipamezole in rat kidney--regional distribution and comparison to alpha2-adrenoceptors.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Female; Idazoxan; Imidazoles; Kidney; Male; Membranes; Monoamine Oxidase; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Adrenergic, alpha-2; Tritium; Yohimbine

1999
Interactions between cutaneous afferent inputs to a withdrawal reflex in the decerebrated rabbit and their control by descending and segmental systems.
    Neuroscience, 2002, Volume: 112, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Decerebrate State; Dexmedetomidine; Dizocilpine Maleate; Drug Synergism; Efferent Pathways; Electric Stimulation; Excitatory Amino Acid Antagonists; Idazoxan; Imidazoles; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Neurons, Afferent; Rabbits; Reflex; Skin; Sural Nerve; Tarsus, Animal

2002
Enhanced stability of wild-type and constitutively active alpha(2A)-adrenoceptors by ligands with agonist, silent and inverse agonist properties.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; CHO Cells; Cricetinae; Drug Interactions; GTP-Binding Proteins; Guanosine Triphosphate; Idazoxan; Imidazoles; Protein Binding; Radioligand Assay; Receptors, Adrenergic, alpha-2; Time Factors; Transfection; Up-Regulation

2002
The alpha2-adrenoceptor antagonist atipamezole reduces the development and expression of d-amphetamine-induced behavioural sensitization.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Behavior, Animal; Dextroamphetamine; Dopamine; Drug Interactions; Idazoxan; Imidazoles; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Motor Activity

2003
Evidence for different pharmacological targets for imidazoline compounds inhibiting settlement of the barnacle Balanus improvisus.
    Journal of experimental zoology. Part A, Comparative experimental biology, 2005, Jul-01, Volume: 303, Issue:7

    Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Agmatine; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Idazoxan; Imidazoles; Imidazolines; Metamorphosis, Biological; Movement; Thoracica

2005
Low doses of alpha 2-adrenoceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance.
    British journal of pharmacology, 2008, Volume: 155, Issue:8

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Idazoxan; Imidazoles; Male; Mianserin; Mirtazapine; Morphine; Rats; Rats, Sprague-Dawley; Spine; Yohimbine

2008
Alpha2-adrenergic impact on hypothalamic magnocellular oxytocinergic neurons in long evans and brattleboro rats: effects of agonist and antagonists.
    Cellular and molecular neurobiology, 2009, Volume: 29, Issue:6-7

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cell Count; Hypothalamus, Anterior; Idazoxan; Imidazoles; Immunohistochemistry; Male; Neurons; Osmolar Concentration; Oxytocin; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Brattleboro; Rats, Long-Evans; Receptors, Adrenergic, alpha-2; Xylazine

2009
Blockade of α2-adrenoceptors induces Arc gene expression in rat brain in a glutamate receptor-dependent manner: a combined qPCR, in situ hybridisation and immunocytochemistry study.
    Neuropharmacology, 2012, Volume: 63, Issue:6

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Brain Chemistry; Cytoskeletal Proteins; Excitatory Amino Acid Antagonists; Idazoxan; Image Processing, Computer-Assisted; Imidazoles; Immunohistochemistry; In Situ Hybridization; Male; Nerve Tissue Proteins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; RNA; Serotonin

2012