Page last updated: 2024-08-25

artemether and arterolane

artemether has been researched along with arterolane in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Charman, SA; Charman, WN; Chiu, FC; Creek, DJ; Dong, Y; Prankerd, RJ; Vennerstrom, JL1
Chen, X; Hergenrother, PJ; Liu, JO; Posner, GH; Rosenthal, AS; Shapiro, TA; West, DC1
Charman, SA; Charman, WN; Chiu, FC; Creek, DJ; Prankerd, RJ; Ryan, E; Vennerstrom, JL1
Biamonte, MA; Le Roch, KG; Wanner, J1
Fidock, DA; Flannery, EL; Winzeler, EA1
Arbe-Barnes, S; Brun, R; Kocken, CH; Matile, H; Scheurer, C; Thomas, AW; van der Wel, A; Wittlin, S1
Brun, R; Charman, SA; Dorn, A; Maerki, S; Matile, H; Wittlin, S1
Chollet, J; Santo-Tomas, J; Scheurer, C; Snyder, C; Wittlin, S1
Anvikar, AR; Arora, S; Bose, TK; Enosse, S; Gaye, O; Iyer, SS; Jalali, RK; Jha, AC; Kokolomami, J; Krudsood, S; Mohanty, R; Mohanty, S; Mwapasa, V; Ndiaye, JL; Noedl, H; Nyirenda, M; Rao, BHK; Rao, BS; Rao, D; Roy, A; Sagara, I; Saha, N; Sharma, P; Sidibe, B; Starzengruber, P; Swoboda, P; Tangpukdee, N; Thompson, R; Tiacoh, L; Toure, OA; Tshefu, AK; Valecha, N; Yumva, NN1
Iyengar, K; Roepe, PD; Siriwardana, A1

Reviews

2 review(s) available for artemether and arterolane

ArticleYear
Recent advances in malaria drug discovery.
    Bioorganic & medicinal chemistry letters, 2013, May-15, Volume: 23, Issue:10

    Topics: Animals; Antimalarials; Drug Discovery; Humans; Liver; Liver Transplantation; Malaria; Molecular Structure

2013
Using genetic methods to define the targets of compounds with antimalarial activity.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum

2013

Trials

1 trial(s) available for artemether and arterolane

ArticleYear
A Phase 3, Double-Blind, Randomized Study of Arterolane Maleate-Piperaquine Phosphate vs Artemether-Lumefantrine for Falciparum Malaria in Adolescent and Adult Patients in Asia and Africa.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Apr-15, Volume: 62, Issue:8

    Topics: Adolescent; Adult; Africa; Aged; Antimalarials; Artemether; Artemisinins; Asia; Child; Double-Blind Method; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Half-Life; Heterocyclic Compounds, 1-Ring; Humans; India; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Peroxides; Plasmodium falciparum; Quinolines; Spiro Compounds; Young Adult

2016

Other Studies

7 other study(ies) available for artemether and arterolane

ArticleYear
Relationship between antimalarial activity and heme alkylation for spiro- and dispiro-1,2,4-trioxolane antimalarials.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Alkylation; Animals; Antimalarials; Artemisinins; Heme; Humans; Kinetics; Parasitic Sensitivity Tests; Plasmodium falciparum; Spiro Compounds; Structure-Activity Relationship

2008
Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells.
    Journal of medicinal chemistry, 2009, Feb-26, Volume: 52, Issue:4

    Topics: Administration, Oral; Animals; Antimalarials; Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Stability; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Mice; Sulfones

2009
Stability of peroxide antimalarials in the presence of human hemoglobin.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Antimalarials; Artemisinins; Drug Stability; Hemoglobins; Humans; Molecular Structure; Peroxides; Spectrophotometry

2009
Plasmodium vivax: in vitro susceptibility of blood stages to synthetic trioxolane compounds and the diamidine DB75.
    Experimental parasitology, 2006, Volume: 113, Issue:3

    Topics: Animals; Antimalarials; Aotidae; Artemether; Artemisinins; Artesunate; Benzamidines; Chloroquine; Drug Resistance; Heterocyclic Compounds, 1-Ring; Inhibitory Concentration 50; Malaria, Vivax; Parasitemia; Peroxides; Plasmodium falciparum; Plasmodium vivax; Sesquiterpenes; Spiro Compounds; Time Factors

2006
In vitro assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of Plasmodium falciparum.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:1

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Erythrocytes; Heterocyclic Compounds, 1-Ring; Molecular Structure; Peroxides; Plasmodium falciparum; Pyrimethamine; Spiro Compounds

2006
In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models.
    Experimental parasitology, 2007, Volume: 115, Issue:3

    Topics: Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Erythrocytes; Female; Heterocyclic Compounds, 1-Ring; Humans; Malaria; Mice; Parasitemia; Parasitic Sensitivity Tests; Peroxides; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinolines; Spiro Compounds

2007
Endoperoxide Drug Cross-Resistance Patterns for Plasmodium falciparum Exhibiting an Artemisinin Delayed-Clearance Phenotype.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11

    Topics: Adamantane; Antimalarials; Artemether; Artemisinins; Dose-Response Relationship, Drug; Drug Resistance; Heterocyclic Compounds, 1-Ring; Inactivation, Metabolic; Lethal Dose 50; Microbial Sensitivity Tests; Peroxides; Plasmodium falciparum; Spiro Compounds

2016