alrestatin has been researched along with sorbinil in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brubaker, AN; DeRuiter, J; Stein, JL; Whitmer, WL | 1 |
| Belletire, JL; Peterson, MJ; Sarges, R; Schnur, RC | 1 |
| Kador, PF; Kinoshita, JH; Sharpless, NE | 1 |
| Abraham, N; Bellini, F; Dvornik, D; Fung, S; Humber, L; Sestanj, K; Simard-Duquesne, N; Treasurywala, A | 1 |
| Maragoudakis, ME; Richon, AB; Wasvary, JS | 1 |
| Ansari, NH; Bhatnagar, A; Das, B; Liu, SQ; Srivastava, SK | 1 |
| Ares, JJ; Kador, PF; Miller, DD | 1 |
| Das, B; Hair, GA; Srivastava, SK | 1 |
| Gardner, K; Lerman, S; Megaw, J | 1 |
| Chylack, LT; Kador, PF; Kinoshita, JH; Tung, WH | 1 |
| Edwards, MR; O'Brien, MM; Schofield, PJ | 1 |
| Burnakis, TG; Tsai, SC | 1 |
| Gelber, DA; Pfeifer, MA; Schumer, MP | 1 |
3 review(s) available for alrestatin and sorbinil
| Article | Year |
|---|---|
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution | 1985 |
Aldose reductase inhibitors: an update.
Topics: Aldehyde Reductase; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Humans; Imidazoles; Imidazolidines; Isoquinolines; Naphthalenes; Phthalazines | 1993 |
Aldose reductase inhibitors: the end of an era or the need for different trial designs?
Topics: Aldehyde Reductase; Autonomic Nervous System; Diabetic Neuropathies; Enzyme Inhibitors; Humans; Imidazoles; Imidazolidines; Isoquinolines; Naphthalenes; Phthalazines; Time Factors | 1997 |
1 trial(s) available for alrestatin and sorbinil
| Article | Year |
|---|---|
Aldose reductase inhibitors: the end of an era or the need for different trial designs?
Topics: Aldehyde Reductase; Autonomic Nervous System; Diabetic Neuropathies; Enzyme Inhibitors; Humans; Imidazoles; Imidazolidines; Isoquinolines; Naphthalenes; Phthalazines; Time Factors | 1997 |
10 other study(ies) available for alrestatin and sorbinil
| Article | Year |
|---|---|
Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.
Topics: Aldehyde Reductase; Animals; Enzyme Inhibitors; Quinolines; Rats; Stereoisomerism; Structure-Activity Relationship; Sugar Alcohol Dehydrogenases | 1986 |
Spiro hydantoin aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cattle; Diabetes Mellitus, Experimental; Hydantoins; Indicators and Reagents; Lens, Crystalline; Magnetic Resonance Spectroscopy; Rats; Sciatic Nerve; Sorbitol; Spiro Compounds; Structure-Activity Relationship; Sugar Alcohol Dehydrogenases | 1988 |
N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Cattle; Diabetes Mellitus, Experimental; Galactitol; Isoquinolines; Lens, Crystalline; Naphthalenes; Rats; Sorbitol; Sugar Alcohol Dehydrogenases | 1984 |
Isoxazolidine-3,5-diones as lens aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Chemical Phenomena; Chemistry; In Vitro Techniques; Isoxazoles; Kinetics; Lens, Crystalline; Oxazoles; Rats; Sugar Alcohol Dehydrogenases | 1982 |
Inhibition kinetics of human kidney aldose and aldehyde reductases by aldose reductase inhibitors.
Topics: Aldehyde Reductase; Aldehydes; Carbohydrate Dehydrogenases; Chromones; Humans; Imidazoles; Imidazolidines; Isoquinolines; Kidney; Kinetics; Naphthalenes; Phenobarbital; Phthalazines; Quercetin; Quinolones; Substrate Specificity; Sugar Alcohol Dehydrogenases | 1990 |
Synthesis and biological evaluation of irreversible inhibitors of aldose reductase.
Topics: Affinity Labels; Aldehyde Reductase; Animals; Dose-Response Relationship, Drug; Imidazoles; Imidazolidines; Isoquinolines; Rats; Structure-Activity Relationship; Sugar Alcohol Dehydrogenases | 1986 |
Activated and unactivated forms of human erythrocyte aldose reductase.
Topics: Aldehyde Reductase; Diabetes Mellitus; Enzyme Activation; Erythrocytes; Glucose; Glyceraldehyde; Humans; Imidazoles; Imidazolidines; Isoquinolines; Kinetics; NADP; Quercetin; Sorbitol; Sugar Alcohol Dehydrogenases | 1985 |
Optical spectroscopy as an in vitro method to monitor aldose reductase inhibitors in the lens.
Topics: Aldehyde Reductase; Animals; Imidazoles; Imidazolidines; In Vitro Techniques; Isoquinolines; Lens, Crystalline; Quercetin; Rabbits; Rats; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sugar Alcohol Dehydrogenases | 1983 |
Differences in the susceptibility of various aldose reductases to inhibition. II.
Topics: Aldehyde Reductase; Animals; Cataract; Chromones; Female; Humans; Imidazoles; Imidazolidines; Isoquinolines; Lens, Crystalline; Placenta; Pregnancy; Quercetin; Rats; Sugar Alcohol Dehydrogenases; Sugar Alcohols | 1980 |
Inhibition of human brain aldose reductase and hexonate dehydrogenase by alrestatin and sorbinil.
Topics: Aldehyde Reductase; Brain; Carbohydrate Dehydrogenases; Humans; Imidazoles; Imidazolidines; Isoquinolines; Kinetics; Parasympatholytics; Sugar Alcohol Dehydrogenases | 1982 |