alanine and aspirin

alanine has been researched along with aspirin in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.50)18.7374
1990's3 (7.50)18.2507
2000's19 (47.50)29.6817
2010's12 (30.00)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Arvanitakis, C; Bornstein, J; Cooke, HJ; Folscroft, J1
DeWitt, DL; Kraemer, SA; Meade, EA; Shimokawa, T; Smith, WL1
De Weck, AL; Geczy, AF1
Giugliano, D; Lefebvre, PJ; Luyckx, AS1
Abdel-Wahab, YH; Barnett, CR; Flatt, PR; O'Harte, FP1
Ferguson, JJ1
Goepel, E; Niemax, K; Rybakowski, C; Schröder, HJ1
Asai, F; Naganuma, H; Ogawa, T; Sugidachi, A1
Alexander, JC; Anders, RJ; Berink, P; Braunwald, E; Cannon, CP; Caspi, A; Charlesworth, A; Langer, A; Lopez-Sendon, J; McCabe, CH; Skene, A; Toman, J; Wilcox, RG1
McGuire, DK; Newby, LK1
Bozarth, J; Confalone, PN; Forsythe, M; Jin, F; Mousa, SA1
Bhatt, DL; Chew, DP; Sapp, S; Topol, EJ1
Braunwald, E; Cannon, CP; Fitzgerald, A; Fitzgerald, DJ; O'Connor, FF; Shields, DC1
Barbera, FA; Dorsam, RT; Feuerstein, GZ; Friedman, SM; Gibbs, S; Lauver, A; Savion, N; Varon, D; Wang, H; Wang, X1
Halushka, MK; Halushka, PV; Walker, LP1
Bentley, J; Blatt, A; Braunwald, E; Cannon, CP; Caspi, A; Charlesworth, A; Cotter, G; Kaluski, E; Krakover, R; Lewis, B; Marmor, A; McCabe, CH; Michowitz, Y; Milo, O; Reisin, L; Vered, Z; Zimlichman, R1
Cannon, CP; Feske, SK; Murphy, S; Schwamm, LH; Smith, EE1
Atar, S; Birnbaum, Y; Cannon, CP; Murphy, SA; Rosanio, S; Uretsky, BF1
Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM1
Ahnen, DJ; Baron, JA; Barry, EL; Bhat, S; Burke, CA; Grau, MV; Haile, RW; O'Brien, TG; Sandler, RS1
Alonso Castillejos, N; García Iglesias, R; Inglada-Galiana, L; Martín Gil, FJ; San Miguel Hernández, A1
Handa, O; Ichikawa, H; Isozaki, Y; Kajikawa, H; Kokura, S; Matsui, H; Naito, Y; Nakabe, N; Suzuki, T; Takagi, T; Yoshida, N; Yoshikawa, T1
Goto, S; Kawai, T; Yamagishi, T1
Asaka, M; Kamada, G; Kato, M; Nishida, M; Nishida, U; Ono, S; Shimizu, Y; Yoshida, T1
Abe, T; Fujioka, T; Inoue, K; Kodama, M; Mizukami, K; Murakami, K; Okimoto, T; Uchida, M1
Fujita, T; Kato, M; Katsuki, S; Kurokawa, S; Nishikawa, K; Ohira, K; Ohta, H; Saitoh, Y; Sato, Y; Yamada, M1
Fukui, H; Hida, N; Hori, K; Miwa, H; Nakamura, S; Ogawa, T; Ohda, Y; Okugawa, T; Oshima, T; Tomita, T; Tozawa, K; Watari, J1
Furuta, T; Sugimoto, M; Uotani, T1
Bereta, G; Buda, A; Chomyszyn-Gajewska, M; Gawron, K; Koziel, J; Lazarz, M; Lazarz-Bartyzel, K; Mizgalska, D; Nowakowska, Z; Oruba, Z; Potempa, J; Szmigielski, B1
Amagase, K; Hashimoto, E; Itayama, M; Izuhara, C; Takayama, S; Takeuchi, K1
Arakawa, T; Fujimoto, K; Handa, O; Higuchi, K; Naito, Y; Sakata, Y; Shiba, M; Takeuchi, T; Tanigawa, T; Watanabe, T; Yoshikawa, T1
Chen, QK; Lai, Y; Li, JY; Ouyang, H; Shan, TD; Xia, ZS; Yang, HS; Yu, T; Zhong, W1
Chen, Z; Hu, L; Jiang, S; Lin, F; Song, H; Tong, S; Wen, C; Zhang, J; Zhang, X1
Dohi, O; Fukui, A; Handa, O; Higashimura, Y; Ishikawa, T; Itoh, Y; Kamada, K; Katada, K; Konishi, H; Majima, A; Mukai, R; Naito, Y; Okayama, T; Suyama, Y; Takagi, T; Takayama, S; Uchiyama, K; Ushiroda, C; Yasuda-Onozawa, Y; Yoshida, N1
Chaitongrat, S; Lertsuwunseri, V; Mahachai, V; Pittayanon, R; Piyachaturawat, P; Prueksapanich, P; Rerknimitr, R; Srimahachota, S1
Chan, HL; Hui, VW; Lui, GC; Tse, YK; Wong, GL; Wong, VW; Yip, TC1
Amini, H; Azhdari Tehrani, H; Haji Aghajani, M; Moradi, O; Pourheidar, E; Rabiei, MM; Sistanizad, M1
Brandt, C; Deinhardt-Emmer, S; Doshi, H; Ehrhardt, C; Giebeler, L; Häring, C; Jungwirth, J; König, S; Löffler, B1
Duffy, EM; Jorgensen, WL1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1

Reviews

2 review(s) available for alanine and aspirin

ArticleYear
Oral platelet glycoprotein IIb/IIIa inhibition.
    Current cardiology reports, 2000, Volume: 2, Issue:5

    Topics: Alanine; Angina, Unstable; Aspirin; Benzamidines; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Syndrome; Treatment Outcome

2000
Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trials.
    Circulation, 2001, Jan-16, Volume: 103, Issue:2

    Topics: Administration, Oral; Alanine; Aspirin; Benzamidines; Clinical Trials, Phase III as Topic; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hemorrhage; Humans; Incidence; Multicenter Studies as Topic; Myocardial Infarction; Oximes; Piperidines; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Randomized Controlled Trials as Topic

2001

Trials

12 trial(s) available for alanine and aspirin

ArticleYear
Oral glycoprotein IIb/IIIa inhibition with orbofiban in patients with unstable coronary syndromes (OPUS-TIMI 16) trial.
    Circulation, 2000, Jul-11, Volume: 102, Issue:2

    Topics: Administration, Oral; Alanine; Anticoagulants; Aspirin; Coronary Disease; Double-Blind Method; Female; Follow-Up Studies; Heparin; Humans; Intracranial Hemorrhages; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Stroke; Survival Analysis; Thrombocytopenia; Treatment Outcome

2000
Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes.
    Blood, 2001, Dec-01, Volume: 98, Issue:12

    Topics: Aged; Alanine; Angina, Unstable; Antigens, Human Platelet; Aspirin; Double-Blind Method; Female; Genetic Variation; Genotype; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Placebos; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Pyrrolidines

2001
Prior peripheral arterial disease and cerebrovascular disease are independent predictors of adverse outcome in patients with acute coronary syndromes: are we doing enough? Results from the Orbofiban in Patients with Unstable Coronary Syndromes-Thrombolysi
    American heart journal, 2003, Volume: 145, Issue:4

    Topics: Aged; Alanine; Aspirin; Cerebrovascular Disorders; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Multivariate Analysis; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Pyrrolidines; Regression Analysis; Risk Factors; Treatment Outcome

2003
Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study.
    American heart journal, 2006, Volume: 151, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Aspirin; Cerebral Hemorrhage; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Ischemic Attack, Transient; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Proportional Hazards Models; Pyrrolidines; Risk Factors; Stroke; Syndrome; Thrombolytic Therapy

2006
Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial.
    Journal of thrombosis and thrombolysis, 2006, Volume: 22, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Aspirin; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Thrombocytopenia; Thrombosis

2006
Circadian variations of gastrointestinal mucosal damage detected with transnasal endoscopy in apparently healthy subjects treated with low-dose aspirin (ASA) for a short period.
    Journal of atherosclerosis and thrombosis, 2009, Volume: 16, Issue:3

    Topics: Adult; Alanine; Aspirin; Circadian Rhythm; Double-Blind Method; Endoscopy; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Quinolones; Time Factors; Treatment Outcome; Ulcer; Young Adult

2009
Evaluation of small bowel blood flow in healthy subjects receiving low-dose aspirin.
    World journal of gastroenterology, 2011, Jan-14, Volume: 17, Issue:2

    Topics: Adult; Alanine; Anti-Ulcer Agents; Area Under Curve; Aspirin; Blood Flow Velocity; Contrast Media; Cross-Over Studies; Double-Blind Method; Endoscopy; Humans; Intestine, Small; Male; Placebos; Quinolones; Treatment Outcome; Ultrasonography

2011
Aspirin-induced small bowel injuries and the preventive effect of rebamipide.
    World journal of gastroenterology, 2011, Dec-14, Volume: 17, Issue:46

    Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Cross-Over Studies; Double-Blind Method; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Omeprazole; Placebos; Quinolones; Young Adult

2011
A randomized, double-blinded, placebo-controlled, multicenter trial, healing effect of rebamipide in patients with low-dose aspirin and/or non-steroidal anti-inflammatory drug induced small bowel injury.
    Journal of gastroenterology, 2014, Volume: 49, Issue:2

    Topics: Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dietary Proteins; Double-Blind Method; Female; Humans; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Middle Aged; Quinolones; Wound Healing

2014
A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:8

    Topics: Adult; Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Double-Blind Method; Gastric Mucosa; Gastrointestinal Hemorrhage; Healthy Volunteers; Humans; Male; Peptic Ulcer; Platelet Aggregation Inhibitors; Quinolones; Ticlopidine; Young Adult

2014
A multicenter, randomized, double-blind, placebo-controlled trial of high-dose rebamipide treatment for low-dose aspirin-induced moderate-to-severe small intestinal damage.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Aged; Alanine; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Intestinal Diseases; Intestine, Small; Male; Quinolones; Severity of Illness Index; Treatment Outcome

2015
Cytoprotective agent for peptic ulcer prevention in patients taking dual antiplatelet agents: A randomized, double-blind placebo-controlled trial.
    Journal of gastroenterology and hepatology, 2019, Volume: 34, Issue:9

    Topics: Aged; Alanine; Anti-Ulcer Agents; Aspirin; Cilostazol; Clopidogrel; Cytoprotection; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Peptic Ulcer; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Quinolones; Thailand; Ticagrelor; Time Factors; Treatment Outcome

2019

Other Studies

26 other study(ies) available for alanine and aspirin

ArticleYear
Effect of aspirin on sugar, amino acid, and sodium transport in rat jejunum.
    The American journal of physiology, 1979, Volume: 236, Issue:4

    Topics: Alanine; Amino Acids; Animals; Aspirin; Biological Transport, Active; Carbohydrate Metabolism; Jejunum; Male; Rats; Sodium

1979
Molecular basis for the inhibition of prostanoid biosynthesis by nonsteroidal anti-inflammatory agents.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: Acetylation; Alanine; Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; DNA; DNA Restriction Enzymes; Exons; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Serine; Sheep

1990
Histocompatibility antigens and genetic control of the immune response in guinea pigs. I. Specific inhibition of antigen-induced lymphocyte stimulation by alloantisera.
    European journal of immunology, 1974, Volume: 4, Issue:7

    Topics: Alanine; Alleles; Animals; Antibodies; Antibody Formation; Aspirin; Cattle; Cells, Cultured; Cytotoxicity Tests, Immunologic; Dinitrophenols; Glycine; Guinea Pigs; Histocompatibility Antigens; Homozygote; Immune Sera; Immunity, Cellular; Immunization Schedule; Immunoglobulin G; Isoantibodies; Leucine; Lymph Nodes; Lymphocyte Activation; Lymphocytes; Lysine; Ovalbumin; Penicillins; Peptides; Peroxidases; Phenacetin; Skin Tests; Species Specificity

1974
Effects of acetylsalicylic acid on blood glucose, plasma FFA, glycerol, 3-hydroxybutyrate, alanine, C-peptide, glucagon and growth hormone responses to arginine in insulin-dependent diabetics.
    Diabete & metabolisme, 1980, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Alanine; Arginine; Aspirin; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Growth Hormone; Hormones; Humans; Hydroxybutyrates; Insulin; Male; Middle Aged

1980
Glycation of insulin in a cultured insulin-secreting cell line.
    Biochemical Society transactions, 1997, Volume: 25, Issue:1

    Topics: Alanine; Animals; Ascorbic Acid; Aspirin; Cell Fusion; Cell Line; Chromatography, Affinity; Glucose; Glycosylation; Guanidines; Insulin; Insulin Secretion; Islets of Langerhans; Potassium; Rats

1997
Meeting highlights. Highlights of the 48th scientific sessions of the American College of Cardiology.
    Circulation, 1999, Aug-10, Volume: 100, Issue:6

    Topics: Abciximab; Alanine; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Monoclonal; Aspirin; Benzamidines; Biphenyl Compounds; Cardiology; Cardiovascular Agents; Clinical Trials as Topic; Clopidogrel; Combined Modality Therapy; Coronary Disease; Dalteparin; Defibrillators, Implantable; Double-Blind Method; Enalapril; Endothelial Growth Factors; Fatty Acids, Omega-3; Guanidines; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin Fab Fragments; Laser Therapy; Lymphokines; Metoprolol; Multicenter Studies as Topic; Myocardial Revascularization; Platelet Aggregation Inhibitors; Pyrrolidines; Randomized Controlled Trials as Topic; Simvastatin; Sodium-Hydrogen Exchangers; Stents; Sulfones; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vitamin E

1999
The effect of oxytocin, prostaglandin E2 and acetylsalicylic acid on flow distribution and on the transfer of alanine, glucose and water in isolated perfused guinea pig placentae.
    Placenta, 2000, Volume: 21, Issue:1

    Topics: Alanine; Animals; Aspirin; Biological Transport, Active; Dinoprostone; Female; Glucose; Guinea Pigs; In Vitro Techniques; Kinetics; Maternal-Fetal Exchange; Oxytocin; Perfusion; Placenta; Pregnancy; Water

2000
Antiplatelet and antithrombotic effects of orbofiban, a new orally active GPIIb/IIIa antagonist, in guinea pigs.
    Thrombosis research, 2000, Mar-01, Volume: 97, Issue:5

    Topics: Adenosine Diphosphate; Administration, Oral; Alanine; Animals; Arteriovenous Shunt, Surgical; Aspirin; beta-Alanine; Bleeding Time; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Guinea Pigs; Hemostasis; Hypercholesterolemia; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Thrombosis; Urea

2000
Human platelet alphaIIbeta3 integrin binding affinity and specificity of SJ874: antiplatelet efficacy versus aspirin.
    Coronary artery disease, 2000, Volume: 11, Issue:7

    Topics: Alanine; Aspirin; Bacterial Proteins; Blood Platelets; Cell Adhesion; Cell Line; DNA-Binding Proteins; Epinephrine; Fibrinogen; Fibronectins; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex

2000
Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cell Aggregation; Dose-Response Relationship, Drug; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Peptides; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Rheology; Shear Strength; Temperature; Tirofiban; Tyrosine

2002
Genetic variation in cyclooxygenase 1: effects on response to aspirin.
    Clinical pharmacology and therapeutics, 2003, Volume: 73, Issue:1

    Topics: Adult; Alanine; Aspirin; Blood Platelets; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cysteine; Dinoprost; DNA, Complementary; Ethanol; Female; Glycine; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Polymorphism, Genetic; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Reference Values; Sequence Analysis, DNA; Sex Characteristics; Threonine; Thromboxane B2

2003
Statins are associated with lower risk of gastrointestinal bleeding in patients with unstable coronary syndromes: analysis of the Orbofiban in Patients with Unstable coronary Syndromes-Thrombolysis In Myocardial Infarction 16 (OPUS-TIMI 16) trial.
    American heart journal, 2006, Volume: 151, Issue:5

    Topics: Acute Disease; Administration, Oral; Aged; Alanine; Anticoagulants; Aspirin; Coronary Disease; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Middle Aged; Patient Discharge; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Retrospective Studies; Risk Assessment; Severity of Illness Index; Syndrome

2006
Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention.
    Journal of the National Cancer Institute, 2006, Oct-18, Volume: 98, Issue:20

    Topics: Adenoma; Adenomatous Polyposis Coli; Aged; Alanine; Anticarcinogenic Agents; Aspirin; Colorectal Neoplasms; Female; Folic Acid; Gastrointestinal Agents; Gene Frequency; Genotype; Glycine; Humans; Male; Middle Aged; Ornithine Decarboxylase; Polymorphism, Single Nucleotide; Racial Groups; Randomized Controlled Trials as Topic; Risk Assessment

2006
[Soluble CD40 ligand: a potential marker of cardiovascular risk].
    Revista clinica espanola, 2007, Volume: 207, Issue:8

    Topics: Abciximab; Acute Coronary Syndrome; Alanine; Angina, Unstable; Animals; Antibodies, Monoclonal; Anticoagulants; Aspirin; Atherosclerosis; Biomarkers; Cardiovascular Diseases; CD40 Ligand; Chromosomes, Human, X; Clinical Trials as Topic; Disease Models, Animal; Female; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Mice; Platelet Activation; Platelet Aggregation Inhibitors; Prognosis; Pyrrolidines; Risk Factors; Thrombosis

2007
Prophylactic effect of rebamipide on aspirin-induced gastric lesions and disruption of tight junctional protein zonula occludens-1 distribution.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:3

    Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Cell Line; Cytoprotection; Fluorescent Antibody Technique; Gastric Mucosa; Male; Membrane Proteins; Permeability; Phosphoproteins; Quinolones; Rats; Rats, Sprague-Dawley; Zonula Occludens-1 Protein

2008
Does rebamipide prevent gastric mucosal injury in patients taking aspirin and clopidogrel?
    Digestive diseases and sciences, 2014, Volume: 59, Issue:8

    Topics: Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Quinolones; Ticlopidine

2014
Peptidylarginine deiminase from Porphyromonas gingivalis contributes to infection of gingival fibroblasts and induction of prostaglandin E2 -signaling pathway.
    Molecular oral microbiology, 2014, Volume: 29, Issue:6

    Topics: Adhesins, Bacterial; Alanine; Aspirin; Bacterial Adhesion; Cells, Cultured; Cyclooxygenase 2; Cysteine; Cysteine Endopeptidases; Dinoprostone; Fibroblasts; Gene Knockout Techniques; Gingipain Cysteine Endopeptidases; Gingiva; Humans; Hydrolases; Immunoassay; Intramolecular Oxidoreductases; Mutation; Porphyromonas gingivalis; Prostaglandin-E Synthases; Protein-Arginine Deiminases; Real-Time Polymerase Chain Reaction; Signal Transduction

2014
Effect of rebamipide on gastric bleeding and ulcerogenic responses induced by aspirin plus clopidogrel under stimulation of acid secretion in rats.
    Journal of gastroenterology and hepatology, 2014, Volume: 29 Suppl 4

    Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Disease Models, Animal; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Platelet Aggregation Inhibitors; Quinolones; Rats, Sprague-Dawley; Stomach Ulcer; Ticlopidine; Treatment Outcome

2014
Rebamipide Promotes the Regeneration of Aspirin-Induced Small-Intestine Mucosal Injury through Accumulation of β-Catenin.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Catenin; Body Weight; Cell Division; Cyclooxygenase 2; Dinoprostone; Female; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Permeability; Proto-Oncogene Proteins c-myc; Quinolones; Random Allocation; Regeneration; RNA, Messenger; Tight Junctions

2015
Fisher Discrimination of Metabolic Changes in Rats Treated with Aspirin and Ibuprofen.
    Pharmacology, 2017, Volume: 100, Issue:3-4

    Topics: Acetoacetates; Alanine; Alanine Transaminase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Aspirin; Diagnostic Techniques and Procedures; Hydroxybutyrates; Ibuprofen; Male; Metabolomics; Rats, Sprague-Dawley

2017
Mucus reduction promotes acetyl salicylic acid-induced small intestinal mucosal injury in rats.
    Biochemical and biophysical research communications, 2018, 03-25, Volume: 498, Issue:1

    Topics: Alanine; Animals; Aspirin; Intestinal Mucosa; Intestine, Small; Male; Mucus; Polysorbates; Protective Agents; Quinolones; Rats, Sprague-Dawley

2018
Aspirin Reduces the Incidence of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Receiving Oral Nucleos(t)ide Analog.
    Clinical and translational gastroenterology, 2021, 03-23, Volume: 12, Issue:3

    Topics: Adult; Aged; Alanine; Antiviral Agents; Aspirin; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Guanine; Hepatitis B, Chronic; Hong Kong; Humans; Incidence; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Tenofovir

2021
Decreased in-hospital mortality associated with aspirin administration in hospitalized patients due to severe COVID-19.
    Journal of medical virology, 2021, Volume: 93, Issue:9

    Topics: Adenosine Monophosphate; Adult; Aged; Alanine; Antiviral Agents; Aspirin; Blood Platelets; Coronary Artery Disease; COVID-19; COVID-19 Drug Treatment; Diabetes Mellitus; Disseminated Intravascular Coagulation; Drug Combinations; Female; Hospital Mortality; Humans; Hypertension; Iran; Lopinavir; Lung; Male; Middle Aged; Platelet Aggregation Inhibitors; Pulmonary Embolism; Respiration, Artificial; Retrospective Studies; Ritonavir; SARS-CoV-2; Severity of Illness Index; Survival Analysis; Treatment Outcome

2021
D,L-Lysine-Acetylsalicylate + Glycine (LASAG) Reduces SARS-CoV-2 Replication and Shows an Additive Effect with Remdesivir.
    International journal of molecular sciences, 2022, Jun-21, Volume: 23, Issue:13

    Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Aspirin; COVID-19 Drug Treatment; Glycine; Humans; Lysine; SARS-CoV-2

2022
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009