aj 76 and raclopride
aj 76 has been researched along with raclopride in 5 studies
Compound Research Comparison
| Studies (aj 76) | Trials (aj 76) | Recent Studies (post-2010) (aj 76) | Studies (raclopride) | Trials (raclopride) | Recent Studies (post-2010) (raclopride) |
|---|---|---|---|---|---|
| 37 | 0 | 2 | 1,802 | 132 | 419 |
Protein Interaction Comparison
| Protein | Taxonomy | aj 76 (IC50) | raclopride (IC50) |
|---|---|---|---|
| D(2) dopamine receptor | Homo sapiens (human) | 0.052 | |
| D(2) dopamine receptor | Mus musculus (house mouse) | 0.032 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P | 1 |
| Bervoets, K; Brocco, M; Dacquet, C; Girardon, S; Gobert, A; Millan, MJ; Newman-Tancredi, A; Peglion, JL; Rivet, JM; Vian, J | 1 |
| Fang, X; Hu, Z; Levant, B; Min, J; Varady, J; Wang, S; Wu, X | 1 |
| Carlsson, A; Hansson, L; Löfberg, L; Waters, N | 1 |
| Carlsson, A; Lagerkvist, S; Löfberg, L; Piercey, M; Waters, N | 1 |
Other Studies
5 other study(ies) available for aj 76 and raclopride
| Article | Year |
|---|---|
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution | 1990 |
Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: 1. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin
Topics: 2-Naphthylamine; Animals; Body Temperature Regulation; Catalepsy; CHO Cells; Cricetinae; Dopamine Antagonists; Furans; Humans; Male; Prolactin; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Dopamine D2; Recombinant Proteins; Stereoisomerism | 1995 |
Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
Topics: Algorithms; Binding Sites; Computational Biology; Crystallography, X-Ray; Databases, Protein; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Solvents; Structure-Activity Relationship; Tetrahydronaphthalenes; Water | 2003 |
Intracerebral infusion of (+)-AJ76 and (+)-UH232: effects on dopamine release and metabolism in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Corpus Striatum; Dialysis; Dopamine; Dopamine Antagonists; Drug Administration Routes; Homovanillic Acid; Male; Nucleus Accumbens; Raclopride; Rats; Rats, Sprague-Dawley; Salicylamides; Tetrahydronaphthalenes | 1994 |
The dopamine D3 receptor and autoreceptor preferring antagonists (+)-AJ76 and (+)-UH232; a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Corpus Striatum; Dopamine; Dopamine Antagonists; Haloperidol; Male; Microdialysis; Neurons; Nucleus Accumbens; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Salicylamides; Substantia Nigra; Tetrahydronaphthalenes; Ventral Tegmental Area | 1993 |