adenosine and rolipram
adenosine has been researched along with rolipram in 49 studies
Research
Studies (49)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (26.53) | 18.7374 |
| 1990's | 20 (40.82) | 18.2507 |
| 2000's | 11 (22.45) | 29.6817 |
| 2010's | 4 (8.16) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Browne, RG; Howard, HR; Koe, BK; Lebel, LA; Sarges, R; Seymour, PA | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Heller, PH; Levine, JD; Taiwo, YO | 1 |
| Nicholson, D; Sawynok, J; White, TD | 1 |
| Levine, JD; Taiwo, YO | 1 |
| Gaal, L; Illes, P; Schudt, C | 1 |
| Dragunow, M | 1 |
| Fredholm, BB; Lerner, UH; Sahlberg, K | 1 |
| Brown, AM; Donaldson, J; Hill, SJ | 1 |
| Gustafsson, LE; Hedqvist, P; Lundin, J; Wiklund, NP | 1 |
| Fredholm, BB; Li, YO | 1 |
| Klotz, KN; Schirren, CG; Schwabe, U; Ukena, D | 1 |
| Harvey, JA; Winsky, L | 1 |
| Hertting, G; Jackisch, R; Kasakov, L; Strittmatter, H | 1 |
| Fredholm, BB; Jonzon, B | 1 |
| Elfman, L; Fredholm, BB; Lindgren, E; Walum, E | 1 |
| Gustafsson, LE | 1 |
| Fredholm, BB; Sandberg, G | 1 |
| Fredholm, BB; Jonzon, B; Lindström, K | 1 |
| Fredholm, BB; Herrera-Marschitz, M; Jonzon, B; Lindström, K; Ungerstedt, U | 1 |
| Fredholm, BB; Johansson, B | 1 |
| Howell, LL; Landrum, AM | 1 |
| Challiss, RA; Morgan, AJ; Murray, KJ | 1 |
| Altiok, N; Fredholm, BB | 1 |
| Akaike, N; Kawa, K; Uneyama, H; Yamashita, Y | 1 |
| Slakey, LL; Westhead, EW; Xiong, Y | 1 |
| Correia-de-Sá, P; Ribeiro, JA | 1 |
| Arch, JR; Buckle, DR; Connolly, BJ; Fenwick, AE; Foster, KA; Murray, KJ; Readshaw, SA; Smallridge, M; Smith, DG | 1 |
| Brett, J; Karakurum, M; Liao, H; Morris, S; Nowygrod, R; Oz, M; Pinsky, D; Platt, J; Sciacca, R; Van Lookeren Campagne, M | 1 |
| Borisy, FF; Hwang, PN; Ronnett, GV; Snyder, SH | 1 |
| Howell, LL | 1 |
| Carper, HT; Mandell, GL; Sullivan, GW | 1 |
| Eigler, A; Endres, S; Greten, TF; Haslberger, C; Sinha, B; Sullivan, GW | 1 |
| Buster, BL; Linden, J; Scheld, WM; Sullivan, GW | 1 |
| Boyle, D; Eigler, A; Endres, S; Erhardt, S; Firestein, GS; Hartmann, G; Matschke, V | 1 |
| Anderson, R; Cole, PJ; Feldman, C; Ramafi, G; Taylor, GW; Theron, AJ; Wilson, R | 1 |
| Bagorda, A; Cardone, R; Casavola, V; Debellis, L; Guerra, L; Jacobson, KA; Li, AH; Reshkin, SJ | 1 |
| Kilpatrick, EL; Lasley, RD; Mentzer, RM; Narayan, P | 1 |
| Anderson, R; Steel, HC | 1 |
| O'Donnell, JM; Suvarna, NU | 1 |
| Al-Ayadhi, LY; Al-Tuwajri, AS | 1 |
| Lappas, CM; Linden, J; Rieger, JM | 1 |
| Bielenberg, GW; Eggert, B; Fischer, Y; Godes, M; Heiden, S; Hocher, B; Kalk, P; Relle, K; Sharkovska, Y; Ziegler, D | 1 |
| Kondo, Y; Morishima, T; Tsuge, M; Wada, T; Yashiro, M; Yasui, K | 1 |
| Shivanna, M; Srinivas, SP | 1 |
| Duarte, T; Godinho, RO; Menezes-Rodrigues, FS | 1 |
| Cui, Y; Erb, KJ; Gantner, F; Mayer, H; Schuetz, JD; Schymeinsky, J; Tilp, C; Tomsic, C; Wollin, L | 1 |
| Cascalheira, JF; Sebastião, AM; Serpa, A | 1 |
| Gao, F; Ji, M; Wang, J; Yang, S; Zhu, G | 1 |
Other Studies
49 other study(ies) available for adenosine and rolipram
| Article | Year |
|---|---|
4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Cats; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Corpus Striatum; Male; Molecular Structure; Motor Activity; Purinergic Antagonists; Quinoxalines; Rats; Receptors, Purinergic; Sleep; Structure-Activity Relationship; Triazoles | 1990 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Mediation of serotonin hyperalgesia by the cAMP second messenger system.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine; Analgesics; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Isomerism; Male; Nociceptors; Pain; Protein Kinase Inhibitors; Pyrrolidines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Rolipram; Second Messenger Systems; Serotonin; Tetrahydronaphthalenes | 1992 |
Forskolin and phosphodiesterase inhibitors release adenosine but inhibit morphine-evoked release of adenosine from spinal cord synaptosomes.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 5'-Nucleotidase; Adenosine; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Morphine; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rolipram; Spinal Cord; Synaptosomes | 1991 |
Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Dinoprostone; Epoprostenol; Hyperalgesia; Male; Phosphorylation; Protein Kinases; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram; Second Messenger Systems; Sensory Thresholds; Thionucleotides | 1991 |
Effects of phosphodiesterase inhibition on the excitability of hippocampal pyramidal neurons in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Neurons; Phosphodiesterase Inhibitors; Pyramidal Tracts; Pyridazines; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram | 1991 |
Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline.
Topics: Adenosine; Aminophylline; Amygdala; Animals; Brain; Carbolines; Diazepam; Flumazenil; Kindling, Neurologic; Male; Picrotoxin; Pyrazoles; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Purinergic; Rolipram; Seizures; Theophylline; Xanthines | 1990 |
Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvaria.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bone and Bones; Bone Resorption; Cells, Cultured; Colforsin; Cyclic AMP; Mice; Phenylisopropyladenosine; Pyrrolidinones; Receptors, Cyclic AMP; Rolipram; Theophylline | 1987 |
Influence of rolipram on the cyclic 3',5'-adenosine monophosphate response to histamine and adenosine in slices of guinea-pig cerebral cortex.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cerebral Cortex; Cyclic AMP; Female; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Male; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram | 1988 |
Characterization of pre- and post-junctional adenosine receptors in guinea-pig ileum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cholinergic Fibers; Colforsin; Cyclic AMP; Diterpenes; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Phenylisopropyladenosine; Pyrrolidinones; Receptors, Cell Surface; Receptors, Neurotransmitter; Receptors, Purinergic; Rolipram; Synaptic Transmission | 1985 |
Adenosine analogues stimulate cyclic AMP formation in rabbit cerebral microvessels via adenosine A2-receptors.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cats; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; Microcirculation; Phenylisopropyladenosine; Pyrrolidinones; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Rolipram | 1985 |
Evidence for an A2 adenosine receptor in guinea pig lung.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Ligands; Lung; Membranes; Pyrrolidinones; Receptors, Cell Surface; Receptors, Purinergic; Rolipram; Theophylline; Time Factors | 1985 |
Effects of N6-(L-phenylisopropyl)adenosine, caffeine, theophylline and rolipram on the acquisition of conditioned responses in the rabbit.
Topics: Adenosine; Animals; Caffeine; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Phenylisopropyladenosine; Pyrrolidinones; Rabbits; Rolipram; Theophylline | 1987 |
Endogenous adenosine as a modulator of hippocampal acetylcholine release.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Caudate Nucleus; Dipyridamole; Electric Stimulation; Hippocampus; In Vitro Techniques; Pyrrolidinones; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Rolipram; Theophylline | 1984 |
Adenosine receptor mediated inhibition of noradrenaline release from slices of the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Dipyridamole; Electric Stimulation; Hippocampus; Male; Norepinephrine; Phenylisopropyladenosine; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Rolipram; Theophylline; Xanthines | 1984 |
Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Line; Cells, Cultured; Cyclic AMP; Glioma; Humans; Kinetics; Neuroblastoma; Phenylisopropyladenosine; Phosphoric Diester Hydrolases; Pyrrolidinones; Rolipram; Theophylline; Vasodilator Agents | 1984 |
Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Atropine; Choline; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pyrrolidinones; Rolipram; Synaptic Transmission; Tetrodotoxin; Theophylline | 1984 |
Regulation of thymocyte proliferation: effects of L-alanine, adenosine and cyclic AMP in vitro.
Topics: Adenosine; Adenosine Deaminase; Alanine; Animals; Cell Division; Cyclic AMP; Cyclopentanes; Guinea Pigs; Kinetics; Male; Mitosis; Pyrrolidinones; Rolipram; T-Lymphocytes; Theophylline | 1981 |
Adenosine receptor mediated increases and decreases in cyclic AMP in hippocampal slices treated with forskolin.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Diterpenes; Hippocampus; Male; Phenylisopropyladenosine; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Rolipram | 1983 |
On the mechanism by which methylxanthines enhance apomorphine-induced rotation behaviour in the rat.
Topics: Adenosine; Animals; Apomorphine; Brain; Drug Synergism; Male; Motor Activity; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram; Rotation; Theophylline; Xanthines | 1983 |
Further characterization of the binding of the adenosine receptor agonist [3H]CGS 21680 to rat brain using autoradiography.
Topics: Adenosine; Animals; Autoradiography; Cerebral Cortex; Corpus Striatum; Dipyridamole; Hippocampus; Magnesium; Male; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Pyrrolidinones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rolipram; Tritium | 1995 |
Attenuation of hypoxia-induced increases in ventilation by adenosine antagonists in rhesus monkeys.
Topics: Adenosine; Animals; Hypoxia; Macaca mulatta; Male; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinazolines; Respiration; Rolipram; Triazoles | 1995 |
Comparison of the effect of isobutylmethylxanthine and phosphodiesterase-selective inhibitors on cAMP levels in SH-SY5Y neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclase Inhibitors; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Tumor Cells, Cultured | 1993 |
Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Astrocytoma; Bradykinin; Brain Neoplasms; Calcimycin; Calcium; Calmodulin; Colforsin; Cyclic AMP; Dopamine; Egtazic Acid; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Neoplasm Proteins; Pyrrolidinones; Rolipram; Signal Transduction; Tumor Cells, Cultured | 1993 |
Existence of rolipram-sensitive phosphodiesterase in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Bone Marrow Cells; Calcimycin; Calcium Channels; Colforsin; Cyclic AMP; Electrophysiology; Female; In Vitro Techniques; Inosine Triphosphate; Isoquinolines; Male; Megakaryocytes; Nystatin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Rolipram | 1993 |
Role of phosphodiesterase isoenzymes in regulating intracellular cyclic AMP in adenosine-stimulated smooth muscle cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Aorta; Calcium; Calmodulin; Cell Compartmentation; Cell Fractionation; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Dose-Response Relationship, Drug; Hydrolysis; Isoenzymes; Muscle, Smooth, Vascular; Purinones; Pyridazines; Pyrrolidinones; Rolipram; Swine | 1995 |
Evidence that the presynaptic A2a-adenosine receptor of the rat motor nerve endings is positively coupled to adenylate cyclase.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; Female; Imines; In Vitro Techniques; Male; Phenethylamines; Phosphodiesterase Inhibitors; Phrenic Nerve; Purinergic P1 Receptor Agonists; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Purinergic P1; Rolipram | 1994 |
Inhibition of cyclic nucleotide phosphodiesterase by derivatives of 1,3-bis(cyclopropylmethyl)xanthine.
Topics: Adenosine; Alkylation; Animals; Binding Sites; Brain; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Structure-Activity Relationship; Xanthines | 1994 |
Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Animals; Bucladesine; Cattle; Cell Hypoxia; Cyclic AMP; Heart Transplantation; Indoles; Male; Muscle, Smooth, Vascular; Myocardium; Neutrophils; Organ Preservation; Oxindoles; Perfusion; Peroxidase; Pyridazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Second Messenger Systems; Thionucleotides; Transplantation, Heterotopic; Transplantation, Homologous | 1993 |
High-affinity cAMP phosphodiesterase and adenosine localized in sensory organs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Autoradiography; Brain; Cholinesterases; Immunohistochemistry; Male; Olfactory Mucosa; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Retina; Rolipram; Sense Organs; Taste Buds; Tongue | 1993 |
Effects of adenosine agonists on ventilation during hypercapnia, hypoxia and hyperoxia in rhesus monkeys.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Carbon Dioxide; Female; Hypercapnia; Hypoxia; Macaca mulatta; Male; Oxygen; Phenethylamines; Plethysmography; Pyrrolidinones; Receptors, Purinergic; Respiration; Respiratory Function Tests; Rolipram | 1993 |
The specific type IV phosphodiesterase inhibitor rolipram combined with adenosine reduces tumor necrosis factor-alpha-primed neutrophil oxidative activity.
Topics: Adenosine; Carbazoles; Drug Synergism; Humans; In Vitro Techniques; Indoles; Neutrophils; Pentoxifylline; Phenethylamines; Phosphodiesterase Inhibitors; Pyrroles; Pyrrolidinones; Respiratory Burst; Rolipram; Superoxides; Tumor Necrosis Factor-alpha | 1995 |
Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis.
Topics: Adenosine; Adenosine Deaminase; Caffeine; Dipyridamole; Humans; Inosine; Leukocytes, Mononuclear; Lipopolysaccharides; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Rolipram; Tumor Necrosis Factor-alpha; Xanthines | 1997 |
Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: synergy with the type IV phosphodiesterase inhibitor, rolipram.
Topics: Adenosine; Animals; Blood-Brain Barrier; Cell Adhesion; Cyclic AMP; Disease Models, Animal; Drug Synergism; Humans; Leukocytosis; Meningitis, Bacterial; Neutrophil Activation; Neutrophils; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Respiratory Burst; Rolipram; Superoxides; Triazines; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
Suppression of TNF-alpha production in human mononuclear cells by an adenosine kinase inhibitor.
Topics: Adenosine; Adenosine Kinase; Adenosine Monophosphate; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Humans; Interleukin-10; Leukocytes, Mononuclear; Phosphodiesterase Inhibitors; Ribonucleosides; Rolipram; Second Messenger Systems; Thionucleotides; Tumor Necrosis Factor-alpha | 2000 |
CGS 21680, dibutyryl cyclic AMP and rolipram attenuate the pro-inflammatory interactions of the Pseudomonas aeruginosa -derived pigment, 1-hydroxyphenazine, with human neutrophils.
Topics: Adenosine; Antihypertensive Agents; Bucladesine; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Homeostasis; Humans; Neutrophils; Phenazines; Phenethylamines; Phosphodiesterase Inhibitors; Pseudomonas aeruginosa; Rolipram | 2000 |
Activation of A(3) adenosine receptor induces calcium entry and chloride secretion in A(6) cells.
Topics: Adenosine; Animals; Calcium; Calcium Signaling; Cell Line; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dihydropyridines; Electric Conductivity; Epithelial Cells; Kidney; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Receptor, Adenosine A3; Receptors, Purinergic P1; Rolipram; Signal Transduction | 2000 |
Cardiac myocyte adenosine A2a receptor activation fails to alter cAMP or contractility: role of receptor localization.
Topics: Adenosine; Animals; Cyclic AMP; Heart; Heart Ventricles; Humans; Isoproterenol; Male; Myocardial Contraction; Myocardium; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic Agonists; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Rolipram | 2002 |
Dissociation of the PAF-receptor from NADPH oxidase and adenylate cyclase in human neutrophils results in accelerated influx and delayed clearance of cytosolic calcium.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclases; Bucladesine; Calcium; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytosol; Homeostasis; Humans; In Vitro Techniques; Leukocyte Elastase; Luminescent Measurements; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phenethylamines; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Membrane Glycoproteins; Purinergic P1 Receptor Agonists; Radioimmunoassay; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Rolipram; Spectrometry, Fluorescence; Superoxides | 2002 |
Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Animals; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 4; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guanylate Cyclase; Hippocampus; N-Methylaspartate; Neurons; Nitric Oxide Donors; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rolipram | 2002 |
The synergistic effect of adenosine A2A receptors agonist, type IV phosphodiestease inhibitor and ATP-sensitive K channels activation on free radicals production and aggregation of human polymorphoneuclear leukocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine A2 Receptor Agonists; Cell Aggregation; Cell Survival; Cromakalim; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Drug Synergism; Free Radicals; Humans; Luminescent Measurements; Luminol; Neutrophils; Phenethylamines; Phosphodiesterase Inhibitors; Potassium Channels, Inwardly Rectifying; Reactive Oxygen Species; Receptor, Adenosine A2A; Respiratory Burst; Rolipram; Tetradecanoylphorbol Acetate | 2004 |
A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; CD4-Positive T-Lymphocytes; Cell Line; Cyclic AMP; Cyclohexanecarboxylic Acids; Gene Dosage; Humans; Interferon-gamma; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Purines; Receptor, Adenosine A2A; Receptors, Antigen, T-Cell; RNA, Messenger; Rolipram; Triazines; Triazoles | 2005 |
The adenosine A1 receptor antagonist SLV320 reduces myocardial fibrosis in rats with 5/6 nephrectomy without affecting blood pressure.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Pressure; Cell Line; Collagen Type I; Collagen Type III; Creatine Kinase; Cyclohexanes; Endomyocardial Fibrosis; Fibronectins; Glomerular Filtration Rate; Heterocyclic Compounds, 2-Ring; Humans; Male; Molecular Structure; Myocardium; Nephrectomy; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Rolipram; U937 Cells; Xanthines | 2007 |
Theophylline inhibits the differentiation of human monocyte into dendritic cell potentially via adenosine receptor antagonism.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Adult; Apoptosis; Caspase 3; CD11c Antigen; Cell Differentiation; Dendritic Cells; Granulocyte-Macrophage Colony-Stimulating Factor; HLA-DR Antigens; Humans; Interleukin-4; Male; Monocytes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptors, Purinergic P1; Recombinant Proteins; RNA, Small Interfering; Rolipram; Theophylline; Xanthines | 2009 |
Elevated cAMP opposes (TNF-alpha)-induced loss in the barrier integrity of corneal endothelium.
Topics: Actomyosin; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood-Retinal Barrier; Cadherins; Cattle; Colforsin; Cyclic AMP; Electric Impedance; Endothelium, Corneal; Enzyme Activation; Epithelial Cells; Intercellular Junctions; Membrane Proteins; Microtubules; p38 Mitogen-Activated Protein Kinases; Permeability; Phosphoproteins; Rolipram; Tumor Necrosis Factor-alpha; Zonula Occludens-1 Protein | 2010 |
Contribution of the extracellular cAMP-adenosine pathway to dual coupling of β2-adrenoceptors to Gs and Gi proteins in mouse skeletal muscle.
Topics: Adenosine; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Clenbuterol; Colforsin; Cyclic AMP; Diaphragm; Electric Stimulation; Feedback, Physiological; Fenoterol; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Male; Mice; Muscle Contraction; Receptors, Adrenergic, beta-2; Rolipram; Signal Transduction | 2012 |
The absence of mrp4 has no effect on the recruitment of neutrophils and eosinophils into the lung after LPS, cigarette smoke or allergen challenge.
Topics: Adenosine; Allergens; Animals; Asthma; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bronchoalveolar Lavage Fluid; Cyclic AMP; Cytokines; Diketopiperazines; Eosinophils; Heterocyclic Compounds, 4 or More Rings; Lipopolysaccharides; Lung; Mice; Multidrug Resistance-Associated Proteins; Neutrophils; Ovalbumin; Phosphodiesterase 4 Inhibitors; Propionates; Pulmonary Disease, Chronic Obstructive; Quinolines; Rolipram; Smoking; Th2 Cells; Time Factors | 2013 |
Modulation of cGMP accumulation by adenosine A1 receptors at the hippocampus: influence of cGMP levels and gender.
Topics: Adenosine; Adenosine Deaminase; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Female; Hippocampus; Imidazoles; Male; Nitroprusside; Rats; Rats, Wistar; Receptor, Adenosine A1; Rolipram; Triazines; Xanthines | 2014 |
Fear extinction induced by activation of PKA ameliorates anxiety-like behavior in PTSD mice.
Topics: Adenosine; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Extinction, Psychological; Fear; Mammals; Mice; Proto-Oncogene Proteins c-akt; Rolipram; Stress Disorders, Post-Traumatic; TOR Serine-Threonine Kinases | 2023 |