adenosine and inosine
adenosine has been researched along with inosine in 1266 studies
Research
Studies (1,266)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 487 (38.47) | 18.7374 |
| 1990's | 230 (18.17) | 18.2507 |
| 2000's | 179 (14.14) | 29.6817 |
| 2010's | 256 (20.22) | 24.3611 |
| 2020's | 114 (9.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Jordan, F; Wu, A | 1 |
| Dalley, NK; McKernan, PA; Nord, LD; Robins, RK | 1 |
| Cheng, JC; Ishiguro, K; Lin, TS; Sartorelli, AC | 1 |
| Hagos, A; Quirk, S; Salim, S; Seley, KL; Zhang, L | 1 |
| Blevins, JS; Brautigam, CA; Deka, RK; Machius, M; Norgard, MV; Tomchick, DR; Yang, XF | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Abel-Santos, E; Alvarez, Z; Lee, K | 1 |
| An, SH; Au, A; Garza, G; Land, KM; Shokar, A; Tong, E; Wnuk, SF; Zayas, J | 1 |
| Abou-Elkhair, RAI; Allan, PW; Hassan, AEA; Parker, WB; Secrist, JA | 1 |
| Carlson, EE; Goswami, M; Wilke, KE | 1 |
| Cheviet, T; Lefebvre-Tournier, I; Peyrottes, S; Wein, S | 1 |
| Divekar, AY | 1 |
| Ong, KK; Rennie, PI | 1 |
| Wong, JL; Zady, MF | 1 |
| Berne, RM; Rubio, R; Winn, HR | 1 |
| Nagy, M | 1 |
| Armstrong, DM; Fernando, AR; Griffiths, JR; Hendry, WF; O'Donoghue, EP; Perrett, D; Ward, JP; Wickham, JE | 1 |
| Jensen, KF | 1 |
| Königk, E; Rasoul, SA | 1 |
| Berne, RM; Degenring, FH; Rubio, R | 1 |
| Degenring, FH | 1 |
| Benke, PJ; Dittmar, D | 1 |
| Berne, RM; Curnish, RR; Degenring, FH; Rubio, R | 1 |
| McBurney, MW; Whimore, GF | 1 |
| Kostopoulos, GK; Limacher, JJ; Phillis, JW | 1 |
| Berne, RM; Rubio, R; Thomas, RA | 1 |
| Greenspan, J; Love, JD; Orengo, A | 1 |
| Berne, RM; Mustafa, SJ; Rubio, R | 2 |
| Chang, IM; Epps, D; Kimball, AP; Sherwood, E | 1 |
| Borg, DC; Schmidt, J | 1 |
| Fredholm, BB | 1 |
| Londesborough, J | 1 |
| Cohen, A; Martin, DW; Ullman, B | 1 |
| Adachi, K; Halprin, KM; Iizuka, H; Levine, V | 1 |
| Gerlach, E; Schrader, J | 1 |
| Hershfield, MS; Seegmiller, JE; Spector, EB | 1 |
| Seegmiller, JE; Shreier, MH; Waldmann, TA; Watanabe, T | 1 |
| Green, RD | 1 |
| Reem, GH | 2 |
| Schreier, MH; Seegmiller, JE; Watanabe, T | 1 |
| Fischer, HD; Hartmann, W; Kluge, H; Wieczorek, V; Zahlten, W | 1 |
| Anderson, MW; Crutchley, DJ; Eling, TE | 1 |
| Albach, RA; Booden, T; Boonlayangoor, P; Stern, ML | 1 |
| Saebø, J; Ueland, M | 1 |
| Königk, E; Schmidt, G; Walter, RD | 1 |
| Eyring, H; Miles, DL; Miles, DW | 1 |
| Dryden, EE; Manery, JF; Riordan, JR; Woo, YT | 1 |
| Ko, RC; Wong, PC | 1 |
| Nelson, JA | 1 |
| Haddy, FJ | 1 |
| Akkerman, JW; De Bree, PK; De Bruyn, CH; Siegenbeek Van Heukelom, LH; Staal, GE; Stoop, JW; Wadman, SK; Zegers, BJ | 1 |
| Ipata, PL; Mura, U; Sgarrella, F | 1 |
| Cole, AW; Palmer, TN | 1 |
| Gardiner, DG | 1 |
| Klabunde, RE; Mayer, SE | 1 |
| Cooper, DR; Lewis, GP; Lieberman, GE; Webb, H; Westwick, J | 1 |
| Capogrossi, MC; DiGirolamo, M; Francendese, A | 1 |
| Ito, CS; Klabunde, RE; Mayer, SE; Winser, CL | 1 |
| Kim, HD | 2 |
| Fredholm, BB; Hedqvist, P; Vernet, L | 1 |
| Pfadenhauer, EH; Tong, SD | 1 |
| Dowdall, MJ; Lane, DA; Zimmermann, H | 1 |
| Parish, RW | 1 |
| Gerlach, E; Haddy, FJ; Schrader, J | 1 |
| Kemper, R; Osswald, H; Schmitz, HJ | 1 |
| Babb, LR; Cass, CE; Paran, JH; Paterson, AR | 1 |
| Kolassa, N; Stengg, R; Turnheim, K | 4 |
| Mitra, C; Pullman, B; Saran, A | 1 |
| Frick, GP; Lowenstein, JM | 1 |
| Carleton, JS; Gordon, JL; Hutchings, A; Pearson, JD | 1 |
| Rosemeyer, H; Seela, F | 1 |
| Akima, M; Sakai, K | 1 |
| Berne, RM; Miller, WL; Rubio, R; Thomas, RA | 1 |
| Hashimoto, M; Matsunaga, Y; Miyazaki, H | 1 |
| Aviado, DM | 2 |
| Brown, PR; Hartwick, RA; Krstulović, AM | 1 |
| Sakai, K | 1 |
| Granger, DN; Lane, RS; Parker, RE; Taylor, AE; Valleau, JD | 1 |
| Bauvois, B; Bodevin, E; Caen, JP; Dosne, AM; Legrand, C | 1 |
| Dawry, F; Maayan, ML; Volpert, EM | 1 |
| Fabri, P; Fischer, JH; Isselhard, W | 1 |
| Fox, AC; Meilman, H; Reed, GE; Silk, BB | 1 |
| Jochimsen, B; Nygaard, P; Vestergaard, T | 1 |
| Hochstadt, J; Rader, RL | 1 |
| Ijichi, H; Kizu, A; Kuriyama, K; Nakamura, M | 1 |
| Berne, RM; Bockman, EL; Rubio, R | 2 |
| Yousten, AA | 1 |
| Becker, JL | 1 |
| Falcone, G; Ipata, PL; Mura, U; Senesi, S; Sgarrella, F | 1 |
| Naguib, FN; Nash, D | 1 |
| Hovi, T; Raivio, KO | 1 |
| Polmar, SH; Raivio, KO; Schwartz, AL; Stern, RC | 1 |
| Borek, E; Davis, GE; Gehrke, CW; Kuo, KC; Suits, RD; Waalkes, TP | 1 |
| Allen, HW; Mustafa, SJ | 1 |
| Berne, RM; Rubio, R; Van Harn, GL | 1 |
| Young, JD | 2 |
| De Jong, JW; Stam, H | 1 |
| Baue, AE; Chaudry, IH; Sayeed, MM | 1 |
| Allen, PW; Bennett, LL; Carpenter, JW; Hill, DL | 1 |
| Gehrke, CW; Patel, AB | 1 |
| Allan, PW; Bennett, LL | 1 |
| Brown, PR; Hartwick, RA | 1 |
| Matsuda, A; Muneyama, K; Nishida, T; Sato, T; Ueda, T | 1 |
| Adamiak, RW; Barciszewska, MZ; Biala, E; Grzéskowiak, K; Kierzek, R; Kraszewski, A; Markiewicz, WT; Wiewiórowski, M | 1 |
| Jones, CE; Parker, JC; Thomas, JX | 1 |
| Lewin, E | 2 |
| Cass, CE; Paterson, AR | 1 |
| Bull, JM; Chabner, BA; Pinedo, HM; Zaharko, DS | 1 |
| Manandhar, MS; Van Dyke, K | 1 |
| Van Dyke, K | 1 |
| Akaoka, I; Nishida, Y; Nishizawa, T; Yoshimura, T | 1 |
| Cornford, EM; Oldendorf, WH | 1 |
| Horii, D; Imai, S; Katano, Y; Otorii, T; Takeda, K | 1 |
| Chen, MF; Paterson, AR; Paul, B | 1 |
| Clements, GB; Subak-Sharpe, JH | 1 |
| Conklyn, M; Fleit, H; Silber, R; Stebbins, RD | 1 |
| Cane, D; Fox, IH; Gladman, DD; Keystone, EC; Moore, M | 1 |
| Aleksić, S; Popović, DA | 1 |
| Goldammer, E; Lüdemann, HD; Müller, A; Röder, O; Westhof, E | 1 |
| Komarek, J; Parish, GA | 1 |
| Gross, GJ; Hardman, HF; Warltier, DC | 1 |
| Buhl, MR | 1 |
| Gustin, NC; Kemp, RG | 1 |
| Nishikura, K | 4 |
| Garg, KN; Lal, H; Singh, J; Yadav, MS | 1 |
| Booth, ED; Brown, T; Hunter, WN; Leonard, GA | 1 |
| Berne, RM; Curnish, RR; Matherne, GP; Tribble, CG; Zhu, Q | 1 |
| Chang-Chun, C; Flameng, W; Masuda, M; Szabò, Z; Szècsi, J; Szerafin, T; Van Belle, H | 1 |
| Chang-Chun, C; Flameng, W; Masuda, M; Möllhoff, T; Van Belle, H | 1 |
| Coumans, WA; de Groot, MJ; van der Vusse, GJ | 1 |
| Mentzer, RM; Van Wylen, DG; Wang, T | 1 |
| Gait, MJ; Slim, G | 1 |
| Janero, DR; Thakkar, JK; Yarwood, C | 1 |
| Barsacchi, D; Camici, M; Cappiello, M; Del Corso, A; Ipata, PL; Mura, U; Tozzi, MG | 1 |
| Castillo, CJ; Del Valle, M; García, AG; Moro, MA; Sillero, A; Sillero, MA | 1 |
| Baer, HP; Dzimiri, M; Ogbunude, PO; Serignese, V | 1 |
| Flameng, W; Möllhoff, T; Sukehiro, S; Van Aken, H; Van Belle, H | 1 |
| Kather, H | 3 |
| Petersen, A; Quistorff, B | 1 |
| Hedenström, H; Lagerqvist, B; Sylvén, C; Waldenström, A | 1 |
| Airhart, MJ; Blackburn, MR; Church, JK; Knudsen, TB; Otey, SK; Skalko, RG; Winters, RS | 1 |
| Camiña, F; Castro-Gago, M; Lojo, S; Rodríguez-Núñez, A; Rodríguez-Segade, S | 1 |
| Bass, BL; Crain, PF; McCloskey, JA; Polson, AG; Pomerantz, SC | 1 |
| Hassinen, IE; Pekka Raatikainen, MJ; Peuhkurinen, KJ | 1 |
| Aassar, OS; Forrest, JN; Kelley, GG | 1 |
| Chen, CC; Demeulemeester, A; Flameng, W; Hendrikx, M; Masuda, M; Van Belle, H | 1 |
| Franco, R | 1 |
| Gerth, C; Jacobasch, G; Siems, W; Werner, A | 1 |
| Barankiewicz, J; Gruber, HE; Jimenez, R; Uyesaka, J | 1 |
| Lachno, R; Mankad, P; Yacoub, M | 1 |
| Lachno, DR; Smolenski, RT; Suitters, A; Yacoub, MH | 1 |
| Baer, HP; Moorji, A; Ogbunude, PO; Serignese, V | 1 |
| Hertz, L | 1 |
| Lieberman, M; Wagenknecht, B | 1 |
| Burrier, AC; Jeng, AY; Oei, HH | 1 |
| Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Bernauer, W | 1 |
| Osswald, W | 1 |
| Hunt, RD; Isley, MR; Mueller, RA; Norfleet, EA; Saltzman, LS | 1 |
| Johns, RA; Linden, J; Patel, A; Prater, MR; Sullivan, GW | 1 |
| Corfù, NA; Sigel, H | 1 |
| Bartos, D; Muller, P; Trunkey, D; Vlessis, AA | 1 |
| Ambrosio, S; Ballarín, M; Fredholm, BB; Mahy, N | 1 |
| Gordon, EL; Hsu, SS; Meno, JR; Winn, HR; Zhou, JG | 1 |
| Berne, RM; Berr, SS; Headrick, JP; Matherne, GP | 1 |
| Melzig, M | 1 |
| Makita, M | 1 |
| Alzheimer, C; Kargl, L; ten Bruggencate, G | 1 |
| Bass, B; Groudine, M; Sharmeen, L; Sonenberg, N; Weintraub, H | 1 |
| al-Jaser, MH; Baer, HP; Ogbunude, PO | 1 |
| Lai, KM; Wong, PC | 1 |
| Fremes, SE; Furukawa, RD; Li, RK; Mickle, DA; Tumiati, LC; Weisel, RD | 1 |
| Estupiñán, B; Horenstein, BA; Parkin, DW; Schramm, VL | 1 |
| Ibayashi, S; Meno, JR; Ngai, AC; Winn, HR | 1 |
| Flameng, W; Hendrickx, M; Möllhoff, T; Sukehiro, S; Van Belle, H | 1 |
| Bollinger, RR; Canada, AT; Fabian, MA; Watkins, WD; Wyble, CW | 1 |
| Berne, RM; Headrick, JP; Zhu, QY | 1 |
| Gorman, MW; He, MX; Meyer, RA; Romig, GD; Sparks, HV | 1 |
| Friedrichs, GS; Merrill, GF | 1 |
| Aranda, JV; Beharry, K; Farri, E; Laudignon, N | 2 |
| Iatrou, K; Skeiky, YA | 1 |
| Beach, RE; Benedict, CR; Gayden, RH; Watts, BA | 1 |
| Albino-Teixeira, A; Azevedo, I; Branco, D; Osswald, W | 1 |
| Brechler, V; Garbarz, E; Lotersztajn, S; Pavoine, C; Pecker, F | 1 |
| Anderson, JD; Dalley, NK; Jin, A; Jolley, WB; Kini, GD; Larson, SB; Nagahara, K; Robins, RK; Sharma, BS; Smee, DF | 1 |
| Granger, HJ; Meininger, CJ | 1 |
| Dobson, JG; Fenton, RA; Romano, FD | 1 |
| Garg, KN; Gupta, LC; Singh, J; Sudhir, S | 1 |
| Behrman, HR; Lavy, G; Polan, ML | 1 |
| Berne, RM; Coleman, SD; Headrick, JP; Matherne, GP | 1 |
| Bosnjak, ZJ; Kampine, JP; Marijic, J; Monroe, SM; Rooney, RT; Stowe, DF | 1 |
| Epsaro, E; Kiessling, AA; Nureddin, A | 1 |
| Matthews, RG; Rohlman, CE | 1 |
| Ko, KR; Ngai, AC; Winn, HR | 1 |
| Kapel'ko, VI; Kuz'min, AI; Medvedev, OS; Saprygina, TV; Selivanov, VN; Shul'zhenko, VS | 1 |
| Grum, CM; Ketai, LH; Supinski, GS | 1 |
| Eklof, B; Jabs, CM; Neglen, P; Thomas, EJ | 1 |
| Andreoli, SP; Liechty, EA; Mallett, C | 1 |
| Baer, HP; Ogbunude, PO | 1 |
| Blanco, J; Canela, EI; Franco, R; Lluis, C; Mallol, J | 1 |
| Aranda, JV; Beharry, K; Farri, E; Laudignon, N; Rex, J | 1 |
| Kaukinen, L; Kaukinen, S; Metsä-Ketelä, T; Ojanen, R; Riekkinen, H; Wuorela, H | 1 |
| Fideu, MD; Miras-Portugal, MT; Torres, M | 1 |
| Singh, J | 1 |
| Dóbi, I; Junász-Nagy, A; Kékesi, V | 1 |
| Ohta, S; Sato, Y; Shinoda, M | 1 |
| Ballati, L; Manzini, S | 1 |
| Hillered, L; Nilsson, P; Pontén, U; Ungerstedt, U | 1 |
| Barankiewicz, J; Gruber, HE; Jimenez, R; Ronlov, G | 1 |
| de Jong, JW; Van der Meer, P | 1 |
| Heller, LJ; Mohrman, DE | 1 |
| Betcher, SL; Dobbins, JW; Forrest, JN; Knickelbein, RG | 1 |
| Barankiewicz, J; Cohen, A | 2 |
| Holgate, ST; Mann, JS; Renwick, AG | 1 |
| García, RA; Muñoz, A; Pérez-Aranda, A | 1 |
| Heller, LJ; Regal, JF | 2 |
| Achterberg, PW; de Jong, JW; Huizer, T | 1 |
| Ballarin, M; Casas, M; Herrera-Marschitz, M; Ungerstedt, U | 1 |
| Barrett, J; Beechey, RB; Harris, DI; Linstead, D | 1 |
| Adair, TH; Guyton, AC; Montani, JP; Strick, DM | 1 |
| Altschuld, RA; Brierley, GP; Hohl, CM; Wimsatt, DK | 1 |
| Chin, WP; Imai, S; Jin, H; Nakazawa, M | 1 |
| Clarke, K; Headrick, J; Willis, RJ | 1 |
| Barraco, RA; Phillis, JW; Polasek, PM; Thorderson, J; Walter, GA | 1 |
| Jennings, RB; Steenbergen, C | 1 |
| Heller, LJ; Regal, JF; Trachte, GJ | 1 |
| Dobson, JG; Ethier, MF; Hickler, RB | 1 |
| Díaz-Cruz, A; Guinzberg, R; Piña, E; Zentella de Piña, M | 1 |
| Di Patre, PL; Giovannini, MG; Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Lĩdaks, MJ; Mauriņs, JA; Paegle, RA; Zariņa, DzE | 1 |
| Barankiewicz, J; Cheung, R; Cohen, A; Dosch, HM | 1 |
| Bürrig, KF; Kelm, M; Kroll, K; Schrader, J | 1 |
| Khramtsova, SN; Pimenov, AM; Potapova, GI; Shapot, VS; Tikhonov, IuV; Toguzov, RT | 1 |
| Cooperman, BS; Nishikura, K; Smith, JE; Wagner, RW | 1 |
| Carlsson, S; Hagberg, H; Sandberg, M; Skarphedinsson, JO; Thorén, P | 1 |
| Bürrig, KF; Kelm, MK; Kroll, K; Schrader, J | 1 |
| Perko, M; Składanowski, AC; Smoleński, RT; Zydowo, MM | 1 |
| Goossens, F; Van Belle, H; Wynants, J | 2 |
| Tse, CM; Young, JD | 1 |
| Hertz, L; Matz, H | 1 |
| Fox, IH; Tekkanat, KK | 1 |
| Bencherif, M; Berne, RM; Rubio, R | 1 |
| Patterson, PH; Wolinsky, EJ | 1 |
| Coleman, DL; Downs, SM; Eppig, JJ | 1 |
| Andersson, P; Butcher, S; Hagberg, H; Hamberger, A; Lehmann, A; Sandberg, M | 1 |
| Allison, WS; Bullough, DA | 1 |
| Allison, WS; Bullough, DA; Verburg, JG; Yoshida, M | 1 |
| D'Alecy, LG; Frank, RS; Moursi, MM; Podrazik, RM; Zelenock, GB | 1 |
| O'Reagan, MH; Phillis, JW; Walter, GA | 1 |
| Ballarini, P; Borgiani, P; Bottini, E; Lucarini, N | 1 |
| Ibayashi, S; Ko, KR; Monsen, MR; Ngai, AC; Winn, HR | 1 |
| Peterson, WP; Sparks, HV; Wangler, RD | 1 |
| IJzerman, AP; Menkveld, GJ; Thedinga, KH | 1 |
| Askar, AO; Mustafa, SJ | 1 |
| Geiger, JD; LaBella, FS; Nagy, JI | 1 |
| Geiger, JD | 2 |
| Drummond, GI; Mistry, G | 1 |
| Inanami, O; Kuwabara, M; Sato, F | 1 |
| Bozal, J; Canela, EI; Centelles, JJ; Franco, R | 1 |
| McCaman, MW | 1 |
| Fredholm, BB; Söderbäck, U; Sollevi, A | 1 |
| Cooney, DA; Dvorak, JA; Finley, RW | 1 |
| Laten, HM; Valentine, PJ; van Kast, CA | 1 |
| Bünger, R; Soboll, S | 1 |
| Cercignani, G | 1 |
| Hara, N; Kawachi, M; Kiyokawa, H; Kono, N; Kuwajima, M; Mineo, I; Nakajima, H; Wang, YL; Yamada, Y; Yamasaki, T | 1 |
| Bass, BL; Weintraub, H | 1 |
| Fukao, N; Fukumoto, T; Takeo, S; Tanaka, T; Tanonaka, K; Tazuma, Y; Yoshikawa, C | 1 |
| Katsaros, N; Tselepi-Kalouli, E | 1 |
| Kuz'ko, NV | 1 |
| Garg, D; Garg, KN; Lal, H; Singh, J | 1 |
| Wheeler, CP; Yudilevich, DL | 1 |
| Barankiewicz, J; Cohen, A; Dosch, HM | 1 |
| O'Regan, MH; Phillis, JW; Walter, GA | 2 |
| Goers, JW; Kern, PA; Ong, JM; Pedersen, ME | 1 |
| Kootstra, G; Maessen, JG; van der Vusse, GJ; Vork, M | 1 |
| Berne, RM; Rubio, R; Shryock, JC | 1 |
| Magnani, M; Pedata, F; Pepeu, G | 1 |
| Geiger, JD; Johnston, ME; Yago, V | 1 |
| Decking, UK; Juengling, E; Kammermeier, H | 1 |
| Grizzle, W; Jenkins, RL; McDaniel, HB; McDaniel, HG; Parrish, SW | 1 |
| Meagher, RC; Paul, P; Rothmann, SA | 1 |
| Imago, M; Miyake, K; Takeo, S; Tanonaka, K | 1 |
| Dorigo, P; Gaion, RM; Gambarotto, L | 1 |
| Binkhorst, R; Joosten, E; Oei, L; Sinkeler, S; Wevers, R | 1 |
| Holland, MJ | 1 |
| Baker, DC; Dechter, JJ; Hanvey, JC; Hawkins, ES; Suhadolnik, RJ; Tunac, JB | 1 |
| Bassingthwaighte, JB; Sparks, HV | 1 |
| Cushley, MJ; Holgate, ST; Mann, JS; Renwick, AG | 1 |
| Edlund, A; Fitzgerald, GA; Nowak, J; Wennmalm, A; Wennmalm, M | 1 |
| Berne, RM; Park, TS; Rubio, R; Van Wylen, DG | 3 |
| Reid, PG; Routledge, PA; Smith, AP; Watt, AH | 1 |
| Andersson, P; Butcher, S; Hagberg, H; Jacobson, I; Lacarewicz, J; Sandberg, M | 1 |
| Carroll, MJ; Young, M | 1 |
| Gati, WP; Gero, AM; Paterson, AR; Stoyke, AF | 1 |
| Nakayama, DA; Sulaiman, AR; Valen, PA; Veum, J; Wortmann, RL | 1 |
| Kather, H; Waas, W; Wieland, E | 1 |
| Krzanowski, JJ; Polson, JB; Sakamoto, Y; Szentivanyi, A; Urdaneta-Bohorquez, A | 1 |
| Bomfim, V; Jansson, E; Kaijser, L; Schmidt, W; Sollevi, A | 1 |
| Guinzberg, R; Guzman, R; Laguna, I; Piña, E; Zentella, A | 1 |
| Geisbuhler, TP; Johnson, DA; Rovetto, MJ | 1 |
| O'Regan, MH; Phillis, JW; Stair, RE; Walter, GA | 1 |
| Miyake, K; Murai, R; Takeo, S; Tanonaka, K; Tazuma, Y | 1 |
| Iijima, K; Kogure, K; Onodera, H | 1 |
| King, CR; Maguire, MH; Westermeyer, FA | 2 |
| Dobson, JG; Fenton, RA; Ordway, RW | 1 |
| Achterberg, PW; De Jong, JW; Stroeve, RJ | 1 |
| Chiba, S; Haruta, K; Homma, N; Iwatsuki, K; Yamagishi, F | 1 |
| Hiraoka, O; Iguchi, S; Matsuda, A; Satake, H; Ueda, T; Wataya, Y | 1 |
| Müller, MM; Rumpold, H; Schopf, G | 1 |
| Nakayama, DA; Valen, PA; Veum, JA; Wortmann, RL | 1 |
| Baue, AE; Chaudry, IH; Hull, MJ; Sumpio, BE | 1 |
| Belt, JA; Gati, WP; Jakobs, ES; Jarvis, SM; Paterson, AR; Young, JD | 1 |
| Aronow, B; Kaur, K; McCartan, K; Ullman, B | 1 |
| Hashimoto, T; Hayakawa, T; Ikeda, T; Jamshidi, J; Masana, Y; Mogami, H; Morimoto, K | 1 |
| Goldblum, RM; Mills, GC; Schmalstieg, FC | 1 |
| Rutledge, CO; Samet, MK | 1 |
| Dmitrenko, NP; Goroshnikova, TV | 1 |
| Aronow, B; Ullman, B | 1 |
| Plagemann, PG; Wohlhueter, RM | 1 |
| Henderson, JF; Paterson, AR; Young, JD | 1 |
| Akuzawa, Y; Kurashige, S; Mitsuhashi, S | 1 |
| Baxter, GS; Collis, MG; Palmer, DB | 1 |
| Bowditch, J; Brown, AK; Dow, JW | 1 |
| Bisserbe, JC; Marangos, PJ; Patel, J | 1 |
| Marcus, A; Schmidt, A; Seal, SN; Sonenberg, N | 1 |
| Daddona, PE; Geiger, JD; Nagy, JI | 1 |
| Clanachan, AS; Hammond, JR | 2 |
| Fredholm, BB; Hohlbach, G; Schoenberg, MH | 1 |
| Dantzker, DR; Fox, IH; Grum, CM; Simon, RH | 1 |
| Andersson, L; Borgström, E; Harmenberg, J; Helström, L; Koshida, K; Stendahl, U; Wahren, B | 1 |
| Agarwal, KC; Dawicki, DD; Parks, RE | 1 |
| Barnes, LB; Bishop, SH; Kirkpatrick, DS | 1 |
| Ambrus, JL; Bhanalaph, T; Mittelman, A; Murphy, GP | 1 |
| Dewey, V; Kidder, GW | 1 |
| Hosono, R; Kuno, S | 1 |
| Molnár, J; Prágai, B | 1 |
| Meisel, M; Meisel, P | 1 |
| Jyssum, S | 1 |
| Divekar, AY; Fleysher, MH; Hakala, MT; Kenny, LN; Slocum, HK | 1 |
| Maguire, MH; Sim, MK | 1 |
| Magill, CW; Magill, JM | 1 |
| Magill, CW; Magill, JM; Spencer, RR | 1 |
| Berne, RM; Rubio, R | 3 |
| Gilham, PT; Ho, NW | 1 |
| Plagemann, PG | 2 |
| Hochstadt-Ozer, J | 1 |
| Fuller, WD; Orgel, LE; Sanchez, RA | 2 |
| Bonavida, B; Fuchs, S; Sela, M | 1 |
| Berne, RM; Rubio, R; Wiedmeier, VT | 2 |
| Schäfer, G; Schlimme, E; Stahl, KW | 1 |
| Bieck, P; Vapaatalo, H; Westermann, E | 1 |
| Ginsborg, BL; Hirst, GD; Maizels, JV; Walker, J | 1 |
| Ebert, R; Schwabe, U | 1 |
| Kuroda, Y; McIlwain, H | 2 |
| Namm, DH | 1 |
| Bagnara, AS; Finch, LR | 1 |
| Campbell, JN; Phillippe, L; Pickard, MA | 1 |
| McIlwain, H; Pull, I | 3 |
| Cobbin, LB; Einstein, R; Maguire, MH | 1 |
| Hochstadt, J | 1 |
| Chopra, DP; Flaxman, BA; Harper, RA | 1 |
| Hossmann, KA; Kleihues, P; Kobayashi, K | 1 |
| Hashimoto, M; Minaki, Y; Miyazaki, H; Nakamura, K; Nambu, K | 1 |
| Dryden, EE; Manery, JF; Woo, YT | 1 |
| Broom, AD; Christensen, LF | 1 |
| Mori, W; Nakahara, A; Suzuki, S | 1 |
| Gray, MW | 1 |
| Kloos, WE; Mohapatra, N | 1 |
| Evans, FE; Sarma, RH | 1 |
| Heyns, AP; Potgieter, GM; Retief, FP; van den Berg, DJ | 1 |
| Frantsuzova, SB | 1 |
| Shore, B; Shore, V | 1 |
| Caen, JP; Jenkins, CS; Pokutecky, J; Vainer, H | 1 |
| Bellanger, R; Caen, JP; Jenkins, CS; Michel, H | 1 |
| Tritsch, GL; Violante, MJ | 1 |
| Hama, T; Ide, H | 1 |
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| Berry, SJ; Freeman, LS; Swindlehurst, M | 1 |
| Berger, NA; Eichhorn, GL; Tarien, E | 1 |
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| London, RE; Schmidt, PG | 1 |
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| Bretschneider, HJ; Fuchs, C; Gethmann, JW; Knoll, D; Kübler, W; Spieckermann, PG | 1 |
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| Sullivan, JM; Trachtenberg, SC | 1 |
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| Connors, TA; Mandel, HG; Melzack, DH | 1 |
| Minaki, Y; Miyazaki, H | 1 |
| Berne, RM; Rubio, VR; Wiedmeier, T | 1 |
| Pinsky, L; Wood, S | 1 |
| Georgatsos, JG; Tsiftsoglou, AS | 1 |
| Berne, RM; Rubio, R; Schrader, J | 1 |
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| Diaz Quiroz, JF; Eisenberg, E; Levinson, SR; Liscovitch-Brauer, N; Montiel-Gonzalez, MF; Nemes, SE; Rangan, KJ; Rosenthal, JJC; Vallecillo-Viejo, IC | 1 |
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| Aune, TM; Crooke, PS; Farley, VM; Heinrich, RM; Tossberg, JT | 1 |
| Hincks, K; Resendiz, MJE; Skinner, A; Wang, H; Yang, CH | 1 |
| Fu, Q; He, X; Huang, Z; Pan, Z; Shi, X; Tang, T; Yang, W; Zhang, H; Zhang, R | 1 |
| Deffit, SN; Dhakal, A; Hundley, HA; Rajendren, S; Townsend, J; Vadlamani, P | 1 |
| Erdmann, EA; Hundley, HA; Mahapatra, A; Mukherjee, P; Yang, B | 1 |
| Okada, S; Sakurai, M; Yang, Y | 1 |
| Kim, P; Wu, S; Yang, M; Zhou, X | 1 |
| Song, X; Wang, Y; Xu, T | 1 |
| Arcimowicz, Ł; Chruściel, E; Hupp, T; Keegan, L; Kowalski, J; Kurkowiak, M; Marek-Trzonkowska, N; O'Connell, M; Papak, I; Urban-Wójciuk, Z | 1 |
| Alves, M; Beamer, E; Conte, G; Dale, N; de Diego-Garcia, L; Delanty, N; El-Naggar, H; Engel, T; Henshall, DC; Khalil, M; Lacey, A; Rosenow, F; Tian, F | 1 |
| Aune, TM; Crooke, PS; Porter, KP; Tossberg, JT | 1 |
| Appelbaum, L; Buchumenski, I; Eisenberg, E; Holler, K; Junker, JP; Levanon, EY | 1 |
| Antebi, Y; Levanon, EY; Nir, R; Schwartz, S; Shliefer, O; Stelzer, Y; Stern-Ginossar, N; Uzonyi, A | 1 |
| Antonov, KV; Arnautova, AO; Berzina, MY; Dorofeeva, EV; Esipov, RS; Fateev, IV; Kayushin, AL; Konstantinova, ID; Lutonina, OI; Mikhailopulo, IA; Miroshnikov, AI; Paramonov, AS; Tokunova, JA | 1 |
| Arthur, RA; Heemstra, JM; Johnston, HR; Knutson, SD | 1 |
| Duan, Y; Lu, J; Tang, X | 1 |
| Bayam, E; Del-Pozo-Rodríguez, J; Drouard, L; Ennifar, E; Godin, JD; Marek, M; Ramos-Morales, E; Romier, C; Salinas-Giegé, T; Tilly, P; Troesch, E; Wolff, P | 1 |
| Bolund, L; Dong, Z; Gu, W; Huang, J; Kristiansen, K; Lin, L; Luo, Y; Mulder, J; Sjöstedt, E; Uhlén, M; Yang, L; Yin, T; Zhang, Y; Zheng, T | 1 |
| Jantsch, MF; Vesely, C | 1 |
| Gao, J; Hu, X; Huang, X; Li, G; Li, X; Wang, Y | 1 |
| Liu, KF; Owens, MC; Zhang, C | 1 |
| Bridgeman, A; Davis, T; Hvidt, AK; Kassiotis, G; Rehwinkel, J; Rigby, RE; Tan, TK; Tang, Q; Townsend, AR; Young, GR | 1 |
| Bonini, F; Bournia, VK; Gatsiou, A; Mavragani, CP; Ntouros, PA; Pappa, M; Sfikakis, PP; Souliotis, VL; Stamatelopoulos, K; Stellos, K; Tektonidou, MG; Tual-Chalot, S; Vlachogiannis, NI; Zormpas, E | 1 |
| Heide-Jørgensen, MP; Larsen, K | 1 |
| Andries, A; Feyaerts, A; Mekahli, D; Van Schepdael, A | 1 |
| Medvedeva, MV; Muronetz, VI; Pozdyshev, DV; Zharikova, AA | 1 |
| Mansi, L; Pesole, G; Picardi, E | 1 |
| Aune, TM; Crooke, PS; Heinrich, RM; Porter, KP; Tossberg, JT | 1 |
| Ben-Zvi, U; Bressler, N; Cohen-Fultheim, R; Eisenberg, E; Gabay, O; Kopel, E; Levanon, EY; Mann, TD; Roth, SH; Schaffer, AA; Shoshan, Y; Tzur, Z | 1 |
| Ignatev, K; Oleinik, E; Shibaev, M; Zhulai, G | 1 |
| Blank, M; Emanuelli, A; Kadali, VN; Koganti, P; Levy-Cohen, G; Manikoth Ayyathan, D; Paolini, B | 1 |
| Dai, Z; Huang, L; Liu, S; Songyang, Z; Weng, Z; Xiong, Y; Zhu, H | 1 |
| Heemstra, JM; Manuel, BA; Sanford, AA; Sterling, SA | 1 |
| Bae, S; Cheun, JH; Choi, A; Choi, H; Choi, Y; Chung, J; Han, W; Jung, Y; Kim, BG; Kim, C; Kim, HS; Kim, I; Kim, J; Kim, JY; Kim, N; Kim, O; Kwon, S; Lee, AC; Lee, H; Lee, HB; Lee, S; Lee, W; Lee, Y; Noh, J; Ryu, HS; Ryu, SY; Ryu, T; Shin, K; Song, SW; Yeom, H; Yoo, DK | 1 |
| Goncharov, AO; Kliuchnikova, AA; Kuznetsova, KG; Moshkovskii, SA; Shender, VO | 1 |
| Chen, JJ; Ding, JH; Feng, YQ; Li, L; Xie, NB; You, XJ; Yuan, BF | 1 |
| Aw, JGA; Cardilla, A; Heng, JWJ; Heraud-Farlow, J; Ho, YS; Ho, YY; Kaewsapsak, P; Kok, EPL; Lin, M; Liu, H; Nguyen, TA; Peh, KLE; Praditya, A; Reversade, B; Šikić, M; Stanojević, D; Tan, MH; Walkley, C; Wan, Y; Wang, Y; Xue, S; Yi, Z; Zhong, Q | 1 |
| Aa, J; Aa, N; Kong, X; Li, S; Lu, Z; Wang, G; Xu, C; Zhang, R; Zhang, S; Zhang, Y | 1 |
| Blonski, S; Cardigan, R; D'Alessandro, A; Dzieciatkowska, M; Korczyk, PM; Meli, A; Nerguizian, D; Rabcuka, J; Smethurst, PA; Sowemimo-Coker, S; Stephenson, D; Swietach, P; Zaremba, D | 1 |
| Haraguchi, M; Koyanagi, S; Matsunaga, N; Ohdo, S; Okawa, M; Omata, Y; Tsuruta, A | 1 |
| Hundley, HA; Manning, AC; Mukherjee, P; Oakes, EK; Raghava Kurup, R; Vadlamani, P | 1 |
| Ahmad, S; Blancke, G; Botzki, A; de Reuver, R; Declercq, W; Dierick, E; Hessmann, E; Hur, S; Jans, M; Maelfait, J; Nemegeer, J; van Loo, G; Van Nieuwerburgh, F; Vandenabeele, P; Verdonck, S; Vereecke, L | 1 |
| Kruyt, ND; Nossent, AY; Quax, PHA; Woudenberg, T | 1 |
| Aguet, F; Fan, B; Geisinger, JM; Gloudemans, MJ; Li, JB; Li, Q; Li, YI; Ma, JB; Montgomery, SB; Pritchard, JK; Ramaswami, G; Sun, T | 1 |
| Chen, W; Huang, H; Li, Y; Ou, X; Ruan, GX; Wang, J; Xu, S; Zhang, R | 1 |
| Braun, T; Dieterich, C; Garcia-Gonzalez, C; Graumann, J; Kubin, T; Li, X; Maroli, G; Schneider, A; Stellos, K; Wiesnet, M; Wietelmann, A; Yuan, X | 1 |
| Goldeck, M; Gopal, A; Jantsch, MF; Mansouri Khosravi, HR; Rajendra, V; Vesely, C | 1 |
| Acunzo, M; Bagnoli, M; Croce, CM; Distefano, R; Fadda, P; Gasparini, P; Laganà, A; Ma, Q; Marceca, GP; Nigita, G; Rampioni Vinciguerra, GL; Tomasello, L; Xiang, Y | 1 |
| Armaos, A; Broglia, L; Burgas, MT; Delli Ponti, R; Sanchez de Groot, N; Tartaglia, GG; Vandelli, A | 1 |
| Cao, X; Chen, Y; Du, Y; Feng, C; Jin, Q; Liu, H; Xin, K; Xu, JR; Zou, J | 1 |
| Akaiwa, Y; Gutmann, B; Ichinose, M; Kawabata, M; Nakamura, I; Nakamura, T; Shimajiri, Y; Tamai, T; Yagi, Y | 1 |
| Bai, G; Bie, F; Gao, S; Liu, L; Peng, Y; Song, P; Zang, R; Zhang, M; Zhao, J; Zhou, B | 1 |
| Abu Nahia, K; Bochtler, M; Kasprzyk, ME; Misztal, K; Navarrete, C; Niescierowicz, K; Pakuła, A; Pateria, A; Pryszcz, L; Sulej, A; Tralle, E; Winata, C | 1 |
| Cai, J; Chen, Z; Cui, L; Fan, R; Guo, C; Ma, R; Shi, Y; Wang, X; Wang, Y; Yao, L | 1 |
| Cunha, RA; Hinz, S; Lopes, CR; Lopes, JP; Müller, CE; Valada, P; Vielmuth, C | 1 |
| Ding, J; Fu, W; Li, Q; Pei, X; Qin, G; You, X | 1 |
| Bowers, SM; Brown, KL; Cabral, DA; Dancey, P; Sundqvist, M | 1 |
| Chen, M; Chi, W; Chi, Y; Guo, R; Huang, S; Huang, X; Li, L; Shao, ZM; Wu, J; Xiu, B; Xue, J; Yang, B; Zhang, L; Zhang, Q | 1 |
| Jackson, EK; Kessinger, CJ; Kitsios, GD; Lu, MY; Macatangay, BJC; McVerry, BJ; Morris, A; Schaefer, CM | 1 |
| Irwin, DM; Khederzadeh, S; Ren, XD; Wang, MS; Wang, YM; Wu, DD; Ye, LQ; Zhang, JJ; Zhang, YP | 1 |
| Alper, SL; Chun, J; Eichinger, F; Friedman, DJ; Guizelini, D; Kelly, J; McNulty, M; Perez-Gill, C; Pollak, MR; Ribas, GT; Riella, CV; Sampson, MG; Subramanian, B; Tattersfield, CF | 1 |
| Breen, MS; Buxbaum, JD; Cuddleston, WH; Devlin, B; Fan, X; Liang, L; Moore, K; Mossotto, E; Roeder, K; Sanders, SJ; Sestan, N; Sloofman, L; Wang, J; Wang, M; Zhang, B; Zipkowitz, S | 1 |
| Chen, KJ; Gu, DL; Ho, CM; Hsiao, CH; Hsu, YH; Huang, JH; Jen, HW; Jou, YS; Kung, YC; Lang, YD; Lee, HY; Lee, SS; Shen, R; Shih, JH; Wu, CY | 1 |
| Fonzino, A; Pesole, G; Picardi, E | 1 |
| Barzilai, A; Eisenberg, E; Geva, P; Greenberger, S; Karmon, M; Kopel, E; Levanon, EY | 1 |
| Arizaca Maquera, KA; Campos, AR; de la Grange, P; Di, J; Gudlavalleti, B; Hernandez, AG; Lee, DC; Margvelani, G; Miranda Sardón, SC; Nelson, PT; Robil, N; Stamm, S; Wang, WX; Welden, JR | 1 |
| Tang, Y; Yan, L | 1 |
| Cao, J; Guo, J; Huang, C; Li, L; Wang, L; Xiao, M; Xu, X; Yang, L; Zhan, S; Zhang, H; Zhong, T | 1 |
| Beal, PA; Jacobsen, CS; Kragness, S; Mandel, G; Mendoza, HG; Salvador, P; Yung, JF | 1 |
| Bi, Y; Chen, R; Coin, LJM; Guo, X; Li, C; Li, F; Pan, S; Song, J | 1 |
| Bubis, JA; Farafonova, TE; Goncharov, AO; Gorshkov, MV; Ivanov, MV; Kliuchnikova, AA; Kukharsky, MS; Levitsky, LI; Lobas, AA; Moshkovskii, SA; Novikova, SE; Ovchinnikov, RK; Pyatnitskiy, MA; Solovyeva, EM; Tarasova, IA; Zgoda, VG | 1 |
| Liang, MX; Liu, Y; Shi, SF; Tang, YC; Yang, CS; Zhang, Y; Zou, SH | 1 |
| Armbrister, SA; Daniel, RC; Lahiri, S; Liu, Y; Mills, TW; Oh, JH; Okeugo, B; Park, ES; Rhoads, J; Roos, S; Saleh, ZM; van Pijkeren, JP | 1 |
| Gao, Z; Ji, X; Jiang, W; Long, H; Ma, Z; Qu, B; Wang, H; Yi, M; Zhang, L; Zhang, S; Zhang, Y | 1 |
| Arimoto, H; Ikeuchi, Y; Kanesaki, Y; Kawamura, F; Kubota, A; Nanamiya, H; Sekine, Y; Shiwa, Y; Soma, A; Suzuki, T; Tomoe, D; Yoshikawa, H | 1 |
| Brunetti, CR; Emery, RJN; Logan, SR; Seegobin, M | 1 |
| Duan, Y; Zhang, Y | 1 |
| Cai, W; Duan, Y; Li, H; Zhan, D; Zheng, C | 1 |
| Mercer, H; Piontkivska, H; Wales-McGrath, B | 1 |
Reviews
88 review(s) available for adenosine and inosine
| Article | Year |
|---|---|
Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues.
Topics: Antimalarials; Biological Transport; Drug Design; Erythrocytes; Humans; Inhibitory Concentration 50; Malaria; Nucleosides; Nucleotides; Plasmodium falciparum; Purines; Pyrimidines | 2019 |
Immunological aspects of purine metabolism.
Topics: Adenine; Adenosine; Adenosine Deaminase; Antibody Formation; Hormones; Humans; Immunity, Cellular; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Inosine; Lesch-Nyhan Syndrome; Liver; Lymphocyte Activation; Lymphocytes; Mercaptopurine; Models, Biological; Nucleoside Deaminases; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purines; Synaptic Transmission; Uridine | 1977 |
Purine biosynthesis in mutant mammalian cells.
Topics: Adenosine; Amidophosphoribosyltransferase; Amino Sugars; Animals; Cells, Cultured; Cricetinae; Dimethyl Sulfoxide; Fibroblasts; Formates; Glutamine; Glycine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Leukemia, Erythroblastic, Acute; Lung; Lymphocytes; Mutation; Phosphoribosyl Pyrophosphate; Purines; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates | 1977 |
The effect of adenosine on lymphoid cell proliferation and antibody formation.
Topics: Adenosine; Adenosine Deaminase; Antibody Formation; Azepines; Cell Division; Cyclic AMP; Hemolytic Plaque Technique; Humans; Inosine; Lectins; Liver; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Phosphoribosyl Pyrophosphate; Ribonucleosides; Ribose-Phosphate Pyrophosphokinase; Spleen; Uridine | 1977 |
Some clinical and pharmacological applications of high-speed liquid chromatography.
Topics: Adenosine; Adenosine Deaminase; Animals; Chemistry, Clinical; Chromatography, High Pressure Liquid; Dogs; Enzymes; Erythrocytes; Humans; Hypoxanthines; Inosine; Mustard Compounds; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ribonucleotides | 1977 |
Bioassay and pharmacologic evaluation of the adenosine hypothesis.
Topics: Adenosine; Adenosine Monophosphate; Animals; Biological Assay; Coronary Circulation; Hyperemia; Hypoxanthines; Hypoxia; Inosine; Ischemia; Kidney; Muscles; Myocardium; Physical Exertion; Regional Blood Flow; Theophylline | 1977 |
Nucleotide metabolism and cellular damage in myocardial ischemia.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Survival; Coronary Disease; Energy Metabolism; Humans; Hypoxanthine; Hypoxanthines; Inosine; Ion Channels; Myocardial Contraction; Myocardium; Oxygen | 1985 |
Indicator dilution estimation of capillary endothelial transport.
Topics: Adenosine; Amino Acids; Animals; Arabinonucleosides; Blood-Brain Barrier; Capillary Permeability; Cats; Cell Membrane Permeability; Diffusion; Dipyridamole; Dogs; Dye Dilution Technique; Endothelium; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Mathematics; Models, Cardiovascular; Prostaglandins; Serum Albumin, Radio-Iodinated; Sucrose | 1986 |
[Is adenosine the mediator for the regulation of the coronary circulation and for the effect of coronarodilators? Review].
Topics: Adenosine; Adenosine Triphosphate; Aminohydrolases; Aminophylline; Animals; Calcium; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Dipyridamole; Dogs; Hydrogen-Ion Concentration; Hypoxanthines; Hypoxia; Inosine; Nitroglycerin; Oxidative Phosphorylation; Oxygen Consumption; Papaverine; Partial Pressure; Prenylamine; Theophylline; Vasodilator Agents; Verapamil | 1974 |
Adenine nucleotide metabolism in the heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Cardiomegaly; Coronary Vessels; Deamination; Diffusion; Dogs; Erythrocytes; Guinea Pigs; Hypoxanthines; Hypoxia; Inosine; Inosine Nucleotides; Ischemia; Kidney; Liver; Myocardium; Nucleosides; Nucleotidases; Perfusion; Purines; Rabbits; Rats | 1974 |
The role of the membrane in the utilization of nucleic acid precursors.
Topics: Adenine; Adenosine; Bacillus subtilis; Biological Transport; Cell Membrane; Chromatography, Gel; Cytosine; DNA; Escherichia coli; Guanine; Guanosine; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Kinetics; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Purines; Pyrimidines; RNA; Thymine; Uracil; Xanthines | 1974 |
Regulation of coronary blood flow.
Topics: Adenosine; Animals; Chick Embryo; Coronary Circulation; Coronary Vessels; Dogs; Guinea Pigs; Hyperemia; Hypoxanthines; Inosine; Myocardium; Nucleotides; Rats | 1974 |
[Which part of the substrates do RNases react?].
Topics: Adenine Nucleotides; Adenosine; Binding Sites; Chemical Phenomena; Chemistry; Cytosine; Cytosine Nucleotides; Guanine Nucleotides; Guanosine; Inosine; Kinetics; Nucleosides; Ribonucleases; Uridine | 1971 |
[Animal experiments and clinical studies on the role of adenosine in bronchial asthma].
Topics: Adenosine; Adult; Animals; Asthma; Atropine; Basophils; Bronchi; Bronchodilator Agents; Cromolyn Sodium; Double-Blind Method; Female; Hexamethonium Compounds; Humans; Inosine; Lung; Male; Mast Cells; Random Allocation; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Urethane; Vagotomy; Xanthines | 1984 |
Adenine derivatives in epilepsy.
Topics: Adenine Nucleotides; Adenosine; Animals; Anticonvulsants; Cyclic AMP; Epilepsy; Hypoxanthines; Inosine; Mice; Ouabain; Rats; Veratridine | 1980 |
Inosine : a naturally occurring cardiotonic agent.
Topics: Adenosine; Animals; Cardiotonic Agents; Chemical Phenomena; Chemistry; Coronary Circulation; Coronary Disease; Dogs; Drug Interactions; Heart; Hemodynamics; Humans; Hypoxia; Inosine; Receptors, Adrenergic; Species Specificity | 1983 |
Metabolic intervention to affect myocardial recovery following ischemia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; Animals; Citric Acid Cycle; Coronary Circulation; Coronary Disease; Fructosediphosphates; Glucose; Glycogen; Heart; Humans; Inosine; Myocardium; Oxidative Phosphorylation; Ribonucleosides; Ribose | 1984 |
Biased (A-->I) hypermutation of animal RNA virus genomes.
Topics: Adenosine; Adenosine Deaminase; Animals; Biological Evolution; Deamination; Genome, Viral; Humans; Inosine; Mononegavirales; Point Mutation; RNA Editing; RNA Viruses; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Viral | 1994 |
Enzymatic conversion of adenosine to inosine and to N1-methylinosine in transfer RNAs: a review.
Topics: Adenosine; Adenosine Deaminase; Anticodon; Base Sequence; Inosine; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; RNA, Transfer; Transcription, Genetic | 1996 |
Editing of messenger RNA precursors and of tRNAs by adenosine to inosine conversion.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Sequence; Animals; Base Sequence; Humans; Inosine; Molecular Sequence Data; RNA Editing; RNA Precursors | 1999 |
A-to-I editing: new and old sites, functions and speculations.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; Ion Channels; Nervous System; Presynaptic Terminals; Receptors, Neurotransmitter; RNA Editing; RNA-Binding Proteins | 2002 |
A-to-I RNA editing: recent news and residual mysteries.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Inosine; Introns; RNA Editing; RNA Precursors; RNA-Binding Proteins; RNA, Messenger | 2003 |
RNA editing by adenosine deaminases generates RNA and protein diversity.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Sequence; Animals; Anticodon; Base Sequence; Evolution, Molecular; Humans; Inosine; Molecular Sequence Data; Nucleic Acid Conformation; RNA; RNA Editing; Sequence Homology, Amino Acid; Substrate Specificity | 2002 |
Letter from the editor: Adenosine-to-inosine RNA editing in Alu repeats in the human genome.
Topics: Adenosine; Alu Elements; Base Sequence; Computational Biology; Evolution, Molecular; Genome, Human; Humans; Inosine; RNA Editing; Species Specificity | 2005 |
Breaking the central dogma by RNA editing.
Topics: Adenosine; Adenosine Deaminase; Catalysis; Hydrogen Bonding; Inosine; Models, Molecular; Protein Conformation; RNA; RNA Editing; RNA-Binding Proteins | 2006 |
Adenosine-to-inosine RNA editing: perspectives and predictions.
Topics: Adenosine; Animals; Genetic Variation; Genome; Humans; Inosine; RNA Editing | 2006 |
Editor meets silencer: crosstalk between RNA editing and RNA interference.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Animals; Gene Expression Regulation; Humans; Inosine; Introns; Retroelements; RNA Editing; RNA Interference; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Small Interfering | 2006 |
A-to-I editing challenger or ally to the microRNA process.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; MicroRNAs; Models, Biological; Nucleic Acid Conformation; RNA; RNA Editing | 2007 |
RNA editing in regulating gene expression in the brain.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Amino Acid Sequence; Animals; Brain; Gene Expression Regulation; Genome, Human; Humans; Inosine; Molecular Sequence Data; Nerve Tissue Proteins; Nucleic Acid Conformation; RNA Editing; RNA Interference; RNA-Binding Proteins | 2008 |
Synthesis of oligoribonucleotides containing N6-alkyladenosine and 2-methylthio-N6-alkyladenosine.
Topics: Adenosine; Alkylation; Inosine; Methylthioinosine; Models, Biological; Oligoribonucleotides; Organophosphorus Compounds | 2004 |
Elucidating the inosinome: global approaches to adenosine-to-inosine RNA editing.
Topics: Adenosine; Animals; Humans; Inosine; Nucleic Acid Conformation; RNA; RNA Editing | 2011 |
RNA editing by mammalian ADARs.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Amyotrophic Lateral Sclerosis; Animals; Central Nervous System; Genetic Association Studies; Humans; Inosine; Male; Mammals; Mice; Mice, Transgenic; Neurons; Protein Binding; Rats; RNA Editing; RNA Interference; RNA-Binding Proteins; RNA, Double-Stranded | 2011 |
Adenosine-to-inosine RNA editing meets cancer.
Topics: Adenosine; Animals; Humans; Inosine; Neoplasms; RNA Editing | 2011 |
A-to-I RNA editing modulates the pharmacology of neuronal ion channels and receptors.
Topics: Adenosine; Animals; Humans; Inosine; Ion Channels; Nervous System Diseases; Neurotransmitter Agents; Receptors, Cell Surface; RNA Editing | 2011 |
Identification of A-to-I RNA editing: dotting the i's in the human transcriptome.
Topics: Adenosine; Computational Biology; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Inosine; RNA Editing; Transcriptome | 2011 |
Deciphering the functions and regulation of brain-enriched A-to-I RNA editing.
Topics: Adenosine; Animals; Brain; Computational Biology; Genomics; Humans; Inosine; Mutation; Nervous System Diseases; RNA; RNA Editing | 2013 |
ADAR enzyme and miRNA story: a nucleotide that can make the difference.
Topics: Adenosine; Adenosine Deaminase; Gene Expression Regulation; Humans; Inosine; MicroRNAs; Protein Biosynthesis; RNA-Binding Proteins; RNA, Double-Stranded | 2013 |
RNA editome imbalance in hepatocellular carcinoma.
Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Humans; Inosine; Liver Neoplasms; RNA; RNA Editing | 2014 |
Inosine in DNA and RNA.
Topics: Adenosine; Animals; Deamination; Disease; DNA; Humans; Inosine; Models, Genetic; RNA; RNA Editing | 2014 |
A-to-I editing on tRNAs: biochemical, biological and evolutionary implications.
Topics: Adenosine; Adenosine Deaminase; Animals; Evolution, Molecular; Humans; Inosine; RNA Editing; RNA, Transfer | 2014 |
Non-adenosine nucleoside inosine, guanosine and uridine as promising antiepileptic drugs: a summary of current literature.
Topics: Adenosine; Animals; Anticonvulsants; Guanosine; Humans; Inosine; Nucleosides; Uridine | 2015 |
Regulatory factors governing adenosine-to-inosine (A-to-I) RNA editing.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; RNA Editing; RNA-Binding Proteins | 2015 |
The dynamic epitranscriptome: A to I editing modulates genetic information.
Topics: Adenosine; Animals; Deamination; Humans; Immunity, Innate; Inosine; Mammals; RNA Editing; RNA Splicing; RNA, Messenger; Transcriptome | 2016 |
A-to-I editing of coding and non-coding RNAs by ADARs.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Animals; Caenorhabditis elegans; Drosophila melanogaster; Genome; Humans; Inosine; Isoenzymes; MicroRNAs; Ribonuclease III; RNA Editing; RNA, Messenger; Signal Transduction | 2016 |
The Epitranscriptome and Innate Immunity.
Topics: Adenosine; Adenosine Deaminase; Aminohydrolases; Humans; Immunity, Innate; Inosine; RNA Editing; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; Transcriptome | 2015 |
Making the Mark: The Role of Adenosine Modifications in the Life Cycle of RNA Viruses.
Topics: Adenosine; Animals; Flavivirus; Humans; Immunity, Innate; Inosine; Life Cycle Stages; Retroviridae; RNA Editing; RNA Viruses; RNA, Viral; Virus Replication | 2017 |
Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics.
Topics: Adenosine; Adenosine Deaminase; Animals; Drug Resistance; Humans; Inactivation, Metabolic; Inosine; Receptors, Aryl Hydrocarbon; RNA Editing; Tetrahydrofolate Dehydrogenase | 2018 |
Adenosine-to-Inosine RNA Editing in Health and Disease.
Topics: Adenosine; Animals; Deamination; Disease; Homeostasis; Humans; Inosine; RNA; RNA Editing | 2018 |
Celebrating wobble decoding: Half a century and still much is new.
Topics: Adenosine; Archaea; Bacteria; Base Pairing; Deamination; Eukaryota; Evolution, Molecular; Genetic Code; Inosine; Models, Molecular; Nucleic Acid Conformation; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Transfer | 2018 |
A-to-I RNA editing - thinking beyond the single nucleotide.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; Ribonuclease III; RNA Editing; RNA Interference; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Untranslated | 2017 |
Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs.
Topics: Adenosine; Adenosine Deaminase; Animals; Disease; Humans; Inosine; RNA Editing; Transcriptome | 2017 |
The role of A-to-I RNA editing in cancer development.
Topics: Adenosine; Inosine; MicroRNAs; Neoplasms; RNA Editing | 2018 |
In cancer, A-to-I RNA editing can be the driver, the passenger, or the mechanic.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Antineoplastic Agents; Biomarkers, Tumor; Carcinogenesis; Genetic Therapy; Humans; Inosine; Molecular Targeted Therapy; Neoplasms; Oncogenes; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Messenger; Tumor Suppressor Proteins | 2017 |
The evolution and adaptation of A-to-I RNA editing.
Topics: Acclimatization; Adaptation, Physiological; Adenosine; Animals; Base Sequence; Evolution, Molecular; Genomics; Humans; Inosine; RNA; RNA Editing | 2017 |
When MicroRNAs Meet RNA Editing in Cancer: A Nucleotide Change Can Make a Difference.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; MicroRNAs; Neoplasms; RNA Editing; RNA-Binding Proteins | 2018 |
RNA Editing: Unexplored Opportunities in the Cardiovascular System.
Topics: Adenosine; Adenosine Deaminase; Animals; Atherosclerosis; Cardiovascular Diseases; Cathepsins; Cyanosis; Heart; Heart Defects, Congenital; Inosine; Mediator Complex; Regeneration; RNA Editing; Salamandridae; Sequence Analysis, RNA | 2018 |
All I's on the RADAR: role of ADAR in gene regulation.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Animals; Gene Expression Regulation; Heterochromatin; Humans; Inosine; MicroRNAs; RNA Editing; RNA Splicing; RNA, Double-Stranded | 2018 |
Critical review on engineering deaminases for site-directed RNA editing.
Topics: Adenosine; Genetic Engineering; Humans; Inosine; Nucleoside Deaminases; RNA Editing | 2019 |
Adenosine to inosine mRNA editing in fungi and how it may relate to fungal pathogenesis.
Topics: Adenosine; Adenosine Deaminase; Animals; Fungal Proteins; Fungi; Humans; Inosine; RNA Editing; RNA, Fungal; RNA, Messenger | 2018 |
Misincorporation signatures for detecting modifications in mRNA: Not as simple as it sounds.
Topics: Adenosine; Animals; Artifacts; Base Sequence; Genetic Heterogeneity; Genome; High-Throughput Nucleotide Sequencing; Humans; Inosine; Reverse Transcription; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Transfer; Sequence Alignment; Sequence Analysis, RNA; Transcriptome | 2019 |
RNA modifications in structure prediction - Status quo and future challenges.
Topics: Adenosine; Animals; Base Pairing; Base Sequence; Humans; Inosine; Methylation; MicroRNAs; Nucleic Acid Conformation; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Ribosomal; RNA, Small Nuclear; RNA, Transfer; Sequence Analysis, RNA; Transcriptome | 2019 |
Computational approaches for detection and quantification of A-to-I RNA-editing.
Topics: Adenosine; Adenosine Deaminase; Algorithms; Alu Elements; Animals; Genome, Human; Humans; Inosine; RNA; RNA Editing; RNA-Binding Proteins; Sequence Analysis, RNA; Single-Cell Analysis; Software | 2019 |
Current strategies for Site-Directed RNA Editing using ADARs.
Topics: Adenosine; Adenosine Deaminase; Animals; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Genome, Human; Humans; Inosine; Mutagenesis, Site-Directed; Oligoribonucleotides, Antisense; Protein Domains; RNA Editing; RNA-Binding Proteins; RNA, Guide, Kinetoplastida; RNA, Messenger | 2019 |
The adaptive potential of RNA editing-mediated miRNA-retargeting in cancer.
Topics: Adenosine; Adenosine Deaminase; Animals; Gene Expression Regulation, Neoplastic; Humans; Inosine; MicroRNAs; RNA Editing | 2019 |
Using mouse models to unlock the secrets of non-synonymous RNA editing.
Topics: Adenosine; Adenosine Deaminase; Alternative Splicing; Animals; Base Pairing; Base Sequence; Humans; Inosine; Mice; Models, Biological; RNA Editing; RNA Stability; RNA-Binding Proteins; RNA, Messenger; Sequence Analysis, RNA | 2019 |
Nucleoside analogs in the study of the epitranscriptome.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; Nucleic Acid Conformation; Organophosphorus Compounds; Ribonucleotides; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Messenger; S-Adenosylmethionine; Selenium; Staining and Labeling; Transcriptome | 2019 |
Defining the functions of adenosine-to-inosine RNA editing through hematology.
Topics: Adenosine; Adenosine Deaminase; Blood Cells; Humans; Inosine; RNA Editing; RNA-Binding Proteins | 2019 |
Adenosine-to-inosine RNA editing in the immune system: friend or foe?
Topics: Adenosine; Adenosine Deaminase; Animals; Autoimmune Diseases; Autoimmune Diseases of the Nervous System; Humans; Immune System; Inosine; Neoplasms; Nervous System Malformations; RNA Editing | 2020 |
What do editors do? Understanding the physiological functions of A-to-I RNA editing by adenosine deaminase acting on RNAs.
Topics: Adenosine; Adenosine Deaminase; Animals; Brain; Humans; Inosine; Interferon-Induced Helicase, IFIH1; Mice; Receptors, Neurotransmitter; RNA; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded | 2020 |
ALU A-to-I RNA Editing: Millions of Sites and Many Open Questions.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Animals; Humans; Inosine; Primates; RNA Editing; RNA, Double-Stranded; Transcriptome | 2021 |
Proteome Diversification by RNA Editing.
Topics: Adaptation, Biological; Adenosine; Animals; Evolution, Molecular; Genetic Speciation; Genetic Variation; Humans; Inosine; Open Reading Frames; Proteome; RNA Editing; RNA, Double-Stranded; Transcriptome | 2021 |
RNA Editing in Neurological and Neurodegenerative Disorders.
Topics: Adenosine; Amyotrophic Lateral Sclerosis; Animals; Epilepsy; Humans; Inosine; Nervous System Diseases; Neurodegenerative Diseases; Phenotype; RNA Editing | 2021 |
A-to-I RNA editing as a tuner of noncoding RNAs in cancer.
Topics: Adenosine; Adenosine Deaminase; Humans; Inosine; Neoplasms; RNA Editing; RNA-Binding Proteins; RNA, Untranslated | 2020 |
To protect and modify double-stranded RNA - the critical roles of ADARs in development, immunity and oncogenesis.
Topics: Adenosine; Adenosine Deaminase; Animals; Carcinogenesis; Deamination; Humans; Immunity, Innate; Inosine; Neoplasms; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded | 2021 |
Adenosine-to-inosine RNA editing in neurological development and disease.
Topics: Adenosine; Amyotrophic Lateral Sclerosis; Astrocytoma; Bipolar Disorder; Central Nervous System Neoplasms; Epilepsy; Humans; Inosine; Kv1.1 Potassium Channel; MicroRNAs; Receptor, Serotonin, 5-HT2C; Receptors, AMPA; RNA Editing; Schizophrenia; Spasms, Infantile | 2021 |
Protein-based molecular recognition tools for detecting and profiling RNA modifications.
Topics: Adenosine; Inosine; RNA; RNA Editing; Transcriptome | 2021 |
The effects of RNA editing in cancer tissue at different stages in carcinogenesis.
Topics: Adenosine; Animals; Carcinogenesis; Humans; Inosine; Neoplasms; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded | 2021 |
Evolutionary driving forces of A-to-I editing in metazoans.
Topics: Adenosine; Adenosine Deaminase; Animals; Evolution, Molecular; Inosine; RNA; RNA Editing | 2022 |
An I for an A: Dynamic Regulation of Adenosine Deamination-Mediated RNA Editing.
Topics: Adenosine; Adenosine Deaminase; Deamination; Humans; Inosine; RNA; RNA Editing; RNA-Binding Proteins | 2021 |
Recent technical advances in the study of nucleic acid modifications.
Topics: Adenosine; Animals; Cytidine; DNA; DNA Methylation; Epigenesis, Genetic; Genetic Techniques; Humans; Inosine; Pseudouridine; RNA; RNA Processing, Post-Transcriptional; RNA, Messenger | 2021 |
Deciphering the Biological Significance of ADAR1-Z-RNA Interactions.
Topics: Adenosine; Adenosine Deaminase; Animals; DNA, Z-Form; Humans; Inosine; Interferon Type I; Interferon-Induced Helicase, IFIH1; Mice; Protein Isoforms; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded | 2021 |
Adenosine-to-Inosine RNA Editing and
Topics: Adenosine; Epigenesis, Genetic; Inosine; MicroRNAs; RNA Editing | 2022 |
Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine Monophosphate; Humans; Inosine; Neoplasms; Tumor Microenvironment | 2022 |
Interplay between A-to-I Editing and Splicing of RNA: A Potential Point of Application for Cancer Therapy.
Topics: Adenosine; Adenosine Deaminase; Antiviral Agents; Humans; Inosine; Neoplasms; RNA Splicing; RNA-Binding Proteins; RNA, Double-Stranded | 2022 |
Change of Heart: the Epitranscriptome of Small Non-coding RNAs in Heart Failure.
Topics: Adenosine; Cytosine; Epigenesis, Genetic; Guanosine; Heart Failure; Humans; Inosine; Ribose; RNA, Small Untranslated; Transcriptome | 2022 |
How RNA editing keeps an I on physiology.
Topics: Adenosine; Animals; Antiviral Agents; Humans; Inosine; Mammals; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Viral | 2022 |
RNA modifications: importance in immune cell biology and related diseases.
Topics: 5-Methylcytosine; Adenosine; Humans; Inosine; Pseudouridine; RNA | 2022 |
The Many Roles of A-to-I RNA Editing in Animals: Functional or Adaptive?
Topics: Adenosine; Animals; Inosine; RNA; RNA Editing; Transcriptome | 2023 |
Trials
5 trial(s) available for adenosine and inosine
| Article | Year |
|---|---|
Vascular effects of infused adenosine are not mediated by prostacyclin release in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Adult; Epinephrine; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Heart Rate; Hemodynamics; Humans; Hypoxanthine; Hypoxanthines; Inosine; Leg; Male; Regional Blood Flow; Uric Acid | 1987 |
Intravenous infusion of adenosine but not inosine stimulates respiration in man.
Topics: Adenosine; Adult; Blood Pressure; Female; Heart Rate; Humans; Infusions, Intravenous; Inosine; Male; Pulmonary Gas Exchange; Respiration; Tidal Volume | 1987 |
Role of adenosine in dialysis-induced hypotension.
Topics: Adenosine; Aged; Caffeine; Female; Humans; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Models, Biological; Norepinephrine; Renal Dialysis; Sympathetic Nervous System; Vascular Resistance; Vasodilation; Xanthine; Xanthines | 1994 |
Safety, tolerance, and efficacy of adenosine as an additive to blood cardioplegia in humans during coronary artery bypass surgery.
Topics: Adenosine; Adolescent; Cardioplegic Solutions; Cardiovascular Agents; Coronary Artery Bypass; Dopamine; Drug Tolerance; Echocardiography; Female; Heart; Humans; Hypoxanthine; Inosine; Male; Myocardial Stunning; Nitroglycerin; Safety; Vasodilator Agents | 1997 |
Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adult; Aging; Alkaline Phosphatase; Female; Gene Expression Regulation, Enzymologic; Humans; Infant, Newborn; Inosine; Male | 2013 |
Other Studies
1173 other study(ies) available for adenosine and inosine
| Article | Year |
|---|---|
Stereoelectronic factors in the binding of substrate analogues and inhibitors to purine nucleoside phosphorylase isolated from human erythrocytes.
Topics: Binding, Competitive; Deoxyribonucleosides; Erythrocytes; Guanosine; Guanosine Monophosphate; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Kinetics; Methylation; Molecular Conformation; Pentosyltransferases; Protein Binding; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship; Substrate Specificity | 1978 |
Synthesis, structure, and biological activity of certain 2-deoxy-beta-D-ribo-hexopyranosyl nucleosides and nucleotides.
Topics: Adenosine Deaminase; Animals; Antineoplastic Agents; Antiviral Agents; Kinetics; Magnetic Resonance Spectroscopy; Mice; Molecular Conformation; Nucleosides; Nucleotides; Protein Kinases; X-Ray Diffraction | 1987 |
Purine and 8-substituted purine arabinofuranosyl and ribofuranosyl nucleoside derivatives as potential inducers of the differentiation of the Friend erythroleukemia.
Topics: Animals; Antimetabolites; Arabinonucleosides; Cell Differentiation; Cell Division; Cell Line; Chemical Phenomena; Chemistry; Friend murine leukemia virus; Hematopoiesis; Leukemia, Erythroblastic, Acute; Mice; Purine Nucleosides; Ribonucleosides; Structure-Activity Relationship | 1985 |
Unexpected inhibition of S-adenosyl-L-homocysteine hydrolase by a guanosine nucleoside.
Topics: Adenosine; Adenosylhomocysteinase; Calorimetry; Enzyme Inhibitors; Guanosine; Hydrogen Bonding; Hydrolysis; Inosine; Kinetics; Models, Molecular; Thermodynamics | 2003 |
The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum.
Topics: Adenosine Triphosphate; Animals; Bacterial Proteins; Binding Sites; Biological Transport; Calorimetry; Cell Membrane; Cloning, Molecular; Crystallography, X-Ray; Cytoplasm; DNA Primers; Escherichia coli; Genes, Bacterial; Histidine; Humans; Kinetics; Ligands; Lipoproteins; Membrane Proteins; Models, Chemical; Models, Molecular; Nucleosides; Open Reading Frames; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Purines; Rabbits; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Time Factors; Transcription, Genetic; Treponema pallidum | 2006 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Testing nucleoside analogues as inhibitors of Bacillus anthracis spore germination in vitro and in macrophage cell culture.
Topics: Alanine; Animals; Bacillus anthracis; Cell Line; Guanosine; Macrophages; Mice; Spores, Bacterial; Structure-Activity Relationship; Thionucleosides | 2010 |
S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiprotozoal Agents; Cell Culture Techniques; Cell Survival; CHO Cells; Cricetinae; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Metronidazole; Protozoan Proteins; Structure-Activity Relationship; Trichomonas vaginalis; Uridine | 2012 |
6-Methylpurine derived sugar modified nucleosides: Synthesis and in vivo antitumor activity in D54 tumor expressing M64V-Escherichia coli purine nucleoside phosphorylase.
Topics: Animals; Antineoplastic Agents; Carbohydrates; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Escherichia coli; Humans; Mice; Molecular Structure; Neoplasms, Experimental; Nucleosides; Purine-Nucleoside Phosphorylase; Purines; Structure-Activity Relationship | 2016 |
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
Adenosine phosphyorylase activity as distinct from inosine-guanosine phosphorylase activity in Sarcoma 180 cells and rat liver.
Topics: Adenine; Adenosine; Animals; Chloromercuribenzoates; Guanine; Hydrogen-Ion Concentration; Inosine; Kinetics; Liver; Pentosyltransferases; Rats; Sarcoma 180 | 1976 |
Assay errors of cyclic 3', 5'-nucleotide phosphodiesterase activity based on the recovery of adenosine alone using an anionic-exchange resin column.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Deaminase; Animals; Anion Exchange Resins; Chromatography, Ion Exchange; Evaluation Studies as Topic; False Negative Reactions; Hydrogen-Ion Concentration; Inosine; Kinetics; Muscles; Phosphoric Diester Hydrolases; Rats | 1976 |
Kinetics and mechanism of carbon-8 methylation of purine bases and nucleosides by methyl radical.
Topics: Adenine; Adenosine; Caffeine; Guanine; Guanosine; Hot Temperature; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Kinetics; Methods; Methylation; Photochemistry; Purine Nucleosides | 1977 |
Production, metabolism and possible functions of adenosine in brain tissue in situ.
Topics: Adenine Nucleotides; Adenosine; Adenosine Kinase; Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Cerebral Arteries; Cerebrovascular Circulation; Hydrogen; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Purine-Nucleoside Phosphorylase; Rats; Vascular Resistance | 1978 |
Studies on purine transport and on purine content in vacuoles isolated from Saccharomyces cerevisiae.
Topics: Adenosine; Biological Transport; Cell Division; Guanosine; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Organoids; Purines; Saccharomyces cerevisiae; Spheroplasts; Vacuoles | 1979 |
Enhanced preservation of the ischaemic kidney with inosine.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Creatinine; Cyclic AMP; Inosine; Ischemia; Kidney; Kidney Transplantation; Organ Preservation; Perfusion; Phenoxybenzamine; Rats; Rats, Inbred Strains; Tissue Preservation; Tissue Survival | 1976 |
Two purine nucleoside phosphorylases in Bacillus subtilis. Purification and some properties of the adenosine-specific phosphorylase.
Topics: Adenosine; Bacillus subtilis; Guanosine; Inosine; Kinetics; Macromolecular Substances; Molecular Weight; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Substrate Specificity | 1978 |
Catabolism of adenosine 5'-monophosphate in promastigotes of Leishmania tropica.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Hypoxanthines; Inosine; Leishmania; Nucleotidases; Purine-Nucleoside Phosphorylase | 1978 |
Adenine nucleotide metabolism during cardiac hypertrophy and ischemia in rats.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta, Abdominal; Cardiomegaly; Constriction; Heart; Hypoxanthines; Inosine; Ischemia; Male; Myocardium; Physical Exertion; Rats; Thyroxine; Time Factors | 1975 |
Effects of ischemia on adenine nucleotide metabolism and coronary flow during cardiac hypertrophy.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Guinea Pigs; Hypoxanthines; Inosine; Rats | 1975 |
Purine dysfunction in cells from patients with adenosine deaminase deficiency.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphatases; Fibroblasts; Guanosine Triphosphate; Humans; Hypoxanthines; Immunologic Deficiency Syndromes; Inosine; Nucleoside Deaminases; Purines; Pyrimidines; Uridine | 1976 |
Effect of dipyridamole on myocardial adenosine metabolism and coronary flow in hypoxia and reactive hyperemia in the isolated perfused guinea pig heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Dipyridamole; Guinea Pigs; Hyperemia; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Myocardium | 1976 |
Mutants of chinese hamster cells resistant to adenosine.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Carbon Radioisotopes; Cell Count; Cell Division; Cell Line; Cell-Free System; Cricetinae; Drug Resistance; Female; Guanine; Hypoxanthines; Inosine; Inosine Nucleotides; Ketone Oxidoreductases; Mutation; Ovary; Pentosyltransferases; Phosphotransferases; Pyrimidines; Tritium | 1975 |
A potent depressant action of adenine derivatives on cerebral cortical neurones.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Cerebral Cortex; Cyclic AMP; Depression, Chemical; Glutamates; In Vitro Techniques; Inosine; Iontophoresis; Male; Neurons; Rats | 1975 |
Comparison of the adenine nucleotide metabolism of dog atrial and ventricular myocardium.
Topics: Adenine Nucleotides; Adenosine; Animals; Dogs; Heart Atria; Heart Ventricles; Hypoxanthines; Inosine; Inosine Nucleotides; Ischemia; Microscopy, Electron; Myocardium; Nitrogen; Nucleotidases; Organ Specificity; Phosphotransferases; Time Factors | 1975 |
Separation of cyclic AMP from adenine and hypoxanthine, their nucleosides and nucleotides by high voltage paper electrophoresis.
Topics: Adenine; Adenine Nucleotides; Adenosine; Cyclic AMP; Electrophoresis, Paper; Hypoxanthines; Inosine; Inosine Nucleotides; Methods; Ribonucleosides; Ribonucleotides; Time Factors | 1975 |
Uptake of adenosine by dispersed chich embryonic cardiac cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Age Factors; Aminohydrolases; Animals; Chick Embryo; Heart; In Vitro Techniques; Inosine; Inosine Nucleotides; Myocardium; Phosphotransferases | 1975 |
Feedback inhibition by 6-methylthioinosine 3',5'-cyclic monophosphate in tumor cells resistant to the nucleoside.
Topics: Adenosine; Adenosine Kinase; Animals; Binding, Competitive; Carcinoma, Ehrlich Tumor; Drug Resistance; Female; Inosine; Methylthioinosine; Mice; Neoplasms, Experimental; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purines | 1975 |
Free radicals from purine nucleosides after hydroxyl radical attack.
Topics: Adenine; Adenosine; Caffeine; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Free Radicals; Guanosine; Hydroxylation; Imidazoles; Inosine; Purine Nucleosides; Radiation Effects | 1976 |
Release of adenosine-like material from isolated perfused dog adipose tissue following sympathetic nerve stimulation and its inhibition by adrenergic alpha-receptor blockade.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adipose Tissue; Animals; Cyclic AMP; Dogs; Electric Stimulation; Female; Glycerol; Inosine; Perfusion; Phentolamine; Sympathetic Nervous System | 1976 |
Quantitative estimation of 3'5' cyclic AMP phosphodiesterase using anion exchange resin in a batch process.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenosine Monophosphate; Anion Exchange Resins; Binding Sites; Chromatography, Ion Exchange; Cyclic AMP; Ethanol; Guanosine; Hypoxanthines; Inosine; Magnesium; Phosphoric Diester Hydrolases; Protein Binding | 1976 |
Characterization of a cell culture model for the study of adenosine deaminase- and purine nucleoside phosphorylase-deficient immunologic disease.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Bucladesine; Cell Line; Cell Survival; Cyclic AMP; Dexamethasone; Formycins; Immunologic Deficiency Syndromes; Inosine; Nucleoside Deaminases; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Uridine | 1976 |
Adenosine and adenine nucleotides stimulation of skin (epidermal) adenylate cyclase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Enzyme Activation; Inosine; Kinetics; Papaverine; Skin; Swine; Theophylline | 1976 |
Compartmentation of cardiac adenine nucleotides and formation of adenosine.
Topics: Adenine Nucleotides; Adenosine; Animals; Coronary Disease; Cyclic AMP; Guinea Pigs; Hypoxanthines; Inosine; Myocardium | 1976 |
Purine synthesis and excretion in mutants of the WI-L2 human lymphoblastoid line deficient in adenosine kinase (AK) and adenine phosphoribosyltransferase (APRT).
Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Cell Line; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Inosine Nucleotides; Lymphocytes; Models, Biological; Mutation; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purines | 1977 |
Control of cyclic adenosine 3':5'-monophosphate-elevating effect of adenosine in C-1300 murine neuroblastoma in tissue culture.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Cell Line; Cyclic AMP; Drug Interactions; Guanosine; Inosine; Neuroblastoma; Prostaglandins E; Theophylline | 1977 |
Brain acetylcholine, adenine nucleotides and their degradation products after intraperitoneal and intracerebral adenosine administration.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Animals; Brain Chemistry; Cyclic AMP; Female; Hypoxanthines; Injections, Intraperitoneal; Injections, Intraventricular; Inosine; Rats | 1977 |
ADPase activity of isolated perfused rat lung.
Topics: Adenosine; Adenosine Monophosphate; Animals; Apyrase; Inosine; Lung; Phosphoric Monoester Hydrolases; Platelet Aggregation; Rabbits | 1978 |
Entamoeba histolytica: uptake of purine bases and nucleosides during axenic growth.
Topics: Adenine; Adenosine; Animals; Culture Media; Entamoeba histolytica; Guanine; Guanosine; Hypoxanthines; Inosine; Purine Nucleosides; Purines | 1978 |
Cyclic AMP-adenosine binding protein/S-adenosylhomocysteinase from mouse liver. A fraction of adenosine bound is converted to adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Carrier Proteins; Chromatography, Gel; Chromatography, Thin Layer; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Homocysteine; Hydrolases; Hydrolysis; In Vitro Techniques; Inosine; Liver; Mice; Protein Denaturation; Ribose; S-Adenosylhomocysteine | 1979 |
A purine nucleoside hydrolase from Trypanosoma gambiense, purification and properties.
Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Adenosine Monophosphate; Animals; Cell-Free System; Chromatography; Chromatography, DEAE-Cellulose; Guanosine; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Inosine; Isoelectric Focusing; Ligases; N-Glycosyl Hydrolases; Oxidative Phosphorylation; Purine Nucleosides; Purine Nucleotides; Trypanosoma brucei gambiense | 1975 |
Interferon induction: a conformational hypothesis.
Topics: Adenosine; Calorimetry; Glycosides; Inosine; Interferon Inducers; Nucleic Acid Conformation; Poly I-C; Purines | 1979 |
Uptake and metabolism of purine nucleosides and nucleotides in isolated frog skeletal muscle.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Anura; Binding, Competitive; Biological Transport; Biological Transport, Active; Hypoxanthines; Inosine; Inosine Monophosphate; Kinetics; Muscles; Purine Nucleosides; Rana pipiens; Ribonucleotides; Temperature | 1977 |
De novo purine ribonucleotide biosynthesis in adult Angiostrongylus cantonensis (Nematoda: Metastrongyloidea).
Topics: Adenine; Adenosine; Angiostrongylus; Animals; Female; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Male; Metastrongyloidea; Purine Nucleotides | 1979 |
A patient with purine nucleoside phosphorylase deficiency: enzymological and metabolic aspects.
Topics: Adenine; Adenosine; Child; Erythrocytes; Female; Humans; Hypoxanthines; Inosine; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase; Purines; Time Factors | 1977 |
Enzymatic synthesis of [U-14C] ribose-labeled inosine.
Topics: Adenosine; Adenosine Deaminase; Carbon Radioisotopes; Inosine; Purine-Nucleoside Phosphorylase; Ribose; Ribosemonophosphates; Xanthine Oxidase | 1978 |
Action of purine nucleosides on the release of intracellular enzymes from rat lymphocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Glucose; In Vitro Techniques; Inosine; L-Lactate Dehydrogenase; Lymphocytes; Osmolar Concentration; Purine Nucleosides; Rats | 1979 |
A rapid and sensitive fluorimetric assay for adenosine, inosine, and hypoxanthine.
Topics: Adenosine; Animals; Dogs; Hypoxanthines; Inosine; Methods; Spectrometry, Fluorescence | 1979 |
Effects of ischemia on tissue metabolites in red (slow) and white (fast) skeletal muscle of the chicken.
Topics: Adenosine; Adenosine Triphosphate; Animals; Chickens; Glycolysis; Inosine; Ischemia; Male; Muscles; Phosphocreatine | 1979 |
ADP metabolism in vascular tissue, a possible thrombo-regulatory mechanism.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta; Aorta, Thoracic; Blood Coagulation; Blood Vessels; Chromatography, Thin Layer; Guinea Pigs; Inosine; Lung; Male; Muscle, Smooth; Rabbits; Rats; Time Factors | 1979 |
Suppression of food intake by adenosine and inosine.
Topics: Adenosine; Animals; Energy Intake; Feeding Behavior; Inosine; Male; Rats; Satiation | 1979 |
Measurement of adenosine and inosine in heart samples by high pressure liquid chromatography.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Inosine; Male; Myocardium; Rats | 1979 |
Cow red blood cells. III. Postnatal adaptation of energy metabolism in the calf red blood cells.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Blood Glucose; Cattle; Dihydroxyacetone; Energy Metabolism; Erythrocytes; Female; Glyceraldehyde; Glycolysis; Inosine; Lactates; Ribose | 1979 |
Release of adenosine from the rabbit heart by sympathetic nerve stimulation.
Topics: Adenosine; Animals; Chromatography, Affinity; Electric Stimulation; Heart; Inosine; Myocardium; Rabbits; Sympathetic Nervous System | 1979 |
Determination of inosine and adenosine in human plasma using high-performance liquid chromatography and a boronate affinity gel.
Topics: Adenosine; Chromatography, Affinity; Chromatography, High Pressure Liquid; Humans; Inosine; Reference Values | 1979 |
Purine salvage at the cholinergic nerve endings of the Torpedo electric organ: the central role of adenosine.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cholinergic Fibers; Electric Organ; Fishes; Hypoxanthines; Inosine; Synaptosomes | 1979 |
Inhibition of Dictyostelium discoideum beta-glucosidase by purines.
Topics: Adenine; Adenosine; Dictyostelium; Glucose; Glucosidases; Guanosine; Hypoxanthines; Inosine; Kinetics; Myxomycetes; Purines | 1977 |
Release of adenosine, inosine and hypoxanthine from the isolated guinea pig heart during hypoxia, flow-autoregulation and reactive hyperemia.
Topics: Adenosine; Animals; Carbon Radioisotopes; Guinea Pigs; Homeostasis; Hyperemia; Hypoxanthines; Hypoxia; Inosine; Myocardium; Vascular Resistance | 1977 |
Tissue content of adenosine, inosine and hypoxanthine in the rat kidney after ischemia and postischemic recirculation.
Topics: Adenosine; Animals; Hypoxanthines; Inosine; Ischemia; Kidney; Rats; Regional Blood Flow; Theophylline; Time Factors | 1977 |
Inhibition by nitrobenzylthioinosine of adenosine uptake by asynchronous HeLa cells.
Topics: Adenosine; Depression, Chemical; HeLa Cells; Humans; Inosine; Kinetics; Structure-Activity Relationship; Thioinosine; Time Factors | 1977 |
Influence of hexobendine, dipyridamole, dilazep, lidoflazine, inosine and purine riboside on adenosine uptake by the isolated epithelium of guinea pig jejunum.
Topics: Adenosine; Animals; Dilazep; Dipyridamole; Epithelium; Guinea Pigs; Hexobendine; Inosine; Intestinal Absorption; Jejunum; Lidoflazine; Piperazines; Purines; Vasodilator Agents | 1978 |
Molecular orbital studies on the structure of nucleoside analogs. I. Conformation of 8-azapurine nucleosides.
Topics: Adenosine; Aza Compounds; Azaguanine; Hydrogen Bonding; Inosine; Molecular Conformation; Purine Nucleosides | 1978 |
Vectorial production of adenosine by 5'-nucleotidase in the perfused rat heart.
Topics: Adenosine; Adenosine Monophosphate; Animals; Inosine; Male; Myocardium; Nucleotidases; Perfusion; Rats | 1978 |
Uptake and metabolism of adenosine by pig aortic endothelial and smooth-muscle cells in culture.
Topics: Adenine; Adenosine; Animals; Aorta, Thoracic; Biological Transport; Cells, Cultured; Dipyridamole; Endothelium; Inosine; Kinetics; Muscle, Smooth; Papaverine; Swine | 1978 |
Substrate- and product-affinity resins for adenosine deaminase obtained by immobilisation of adenosine and inosine via 2',3'-cyclic acetal derivatives.
Topics: Adenosine; Adenosine Deaminase; Chromatography, Affinity; Inosine; Nucleoside Deaminases; Resins, Plant | 1978 |
Vasoconstriction after adenosine and inosine in the rat isolated hindlimb abolished by blockade of tryptaminergic mechanisms.
Topics: Adenosine; Animals; Femoral Artery; Hindlimb; In Vitro Techniques; Inosine; Male; Methysergide; Rats; Regional Blood Flow; Reserpine; Tryptamines; Vasoconstriction | 1978 |
Adenosine production in the ischemic kidney.
Topics: Adenosine; Animals; Cats; Dogs; Histocytochemistry; Hypoxanthines; Inosine; Kidney; Kidney Tubules; Mitochondria; Nucleotidases; Rats; Renal Artery Obstruction | 1978 |
Distribution of [14C]labeled purines in the mouse. A whole body autoradiographic assessment of purine metabolism in mammals.
Topics: Adenosine; Animals; Autoradiography; Carbon Radioisotopes; Cells, Cultured; Erythrocytes; Hypoxanthines; Inosine; Male; Mice; Organ Specificity; Purines; Thymidine; Uric Acid; Uridine; Xanthines | 1978 |
Effects of fluorocarbons, chlorinated solvents, and inosine on the cardiopulmonary system.
Topics: Adenosine; Aerosol Propellants; Animals; Arrhythmias, Cardiac; Catecholamines; Dogs; Female; Fluorocarbons; Hemodynamics; Hydrocarbons, Chlorinated; Inosine; Male; Methylene Chloride; Myocardial Contraction; Oxygen; Respiration; Solvents | 1978 |
Selective analysis of adenosine, 1-methylinosine and N2-methylguanosine by high pressure liquid chromatography.
Topics: Adenosine; Adenosine Deaminase; Breast Neoplasms; Chromatography, High Pressure Liquid; Female; Guanosine; Humans; Inosine | 1978 |
Tryptaminergic mechanism participating in induction of vasoconstriction by adenine nucleotides, adenosine, IMP and inosine in the isolated and blood-perfused hindlimb preparation of the rat.
Topics: Adenine Nucleotides; Adenosine; Animals; Blood Flow Velocity; Femoral Artery; Femoral Vein; In Vitro Techniques; Inosine; Inosine Monophosphate; Inosine Nucleotides; Male; Methysergide; Perfusion; Rats; Reserpine; Serotonin; Vasoconstriction; Vasoconstrictor Agents | 1978 |
Effects of adenosine on intestinal hemodynamics, oxygen delivery, and capillary fluid exchange.
Topics: Adenosine; Animals; Capillaries; Cats; Female; Hyperemia; Hypoxanthines; Ileum; Inosine; Lymph; Male; Regional Blood Flow | 1978 |
Comparative degradation of adenylnucleotides by cultured endothelial cells and fibroblasts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Adhesion; Cells, Cultured; Endothelium; Female; Fibroblasts; Humans; Inosine; Male; Skin; Umbilical Cord | 1978 |
Inhibition by adenosine of thyroidal T4 release in vitro.
Topics: Adenosine; Animals; Guanosine; Inosine; Mice; Thyroid Gland; Thyrotropin; Thyroxine | 1978 |
[Effect of adenosine and inosine on the metabolic status of preserved kidneys].
Topics: Adenine Nucleotides; Adenosine; Animals; Cold Temperature; Inosine; Kidney; Male; Organ Preservation; Oxygen; Perfusion; Rats; Tissue Preservation | 1978 |
Release of nucleosides from canine and human hearts as an index of prior ischemia.
Topics: Adenosine; Animals; Coronary Disease; Dogs; Homeostasis; Hypoxanthines; Inosine; Lactates; Male; Myocardium; Nucleosides; Time Factors | 1979 |
Location on the chromosome of Escherichia coli of genes governing purine metabolism. Adenosine deaminase (add), guanosine kinase (gsk) and hypoxanthine phosphoribosyltransferase (hpt).
Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Chromosome Deletion; Chromosome Mapping; Chromosomes, Bacterial; Conjugation, Genetic; Escherichia coli; Genes; Guanine; Guanosine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Mutation; Nucleoside Deaminases; Pentosyltransferases; Purines; Recombination, Genetic; Transduction, Genetic; Transferases; Xanthines | 1975 |
Regulation of purine utilization in bacteria. VII. Involvement of membrane-associated nucleoside phosphorylase in the uptake and the base-mediated loss of the ribose moiety of nucleosides by Salmonella typhimurium membrane vesicles.
Topics: Adenosine; Biological Transport, Active; Cell Membrane; Inosine; Nucleosides; Pentosephosphates; Pentosyltransferases; Ribosemonophosphates; Salmonella typhimurium; Succinates; Sulfhydryl Reagents; Uncoupling Agents; Uracil; Uridine; Uridine Phosphorylase | 1976 |
A simple and rapid microassay method for adenosine using combined effects of isotope dilution and enzymatic catalysis.
Topics: Adenosine; Animals; Catalysis; Enzymes; Inosine; Methods; Microchemistry; Myocardium; Radioisotope Dilution Technique; Rats | 1976 |
Release of adenosine and lack of release of ATP from contracting skeletal muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dogs; Edetic Acid; Female; Hindlimb; Hyperemia; Hypoxanthines; Inosine; Male; Muscle Contraction; Muscles; Perfusion; Rats | 1975 |
Germination of Bacillus cereus endospores: a proposed role for heat shock and nucleosides.
Topics: Adenosine; Alanine; Alanine Racemase; Bacillus cereus; Hot Temperature; Inosine; Nucleosides; Spores, Bacterial; Stereoisomerism; Time Factors | 1975 |
[Purine metabolism in cultured Drosophila melanogaster cells: adenosine utilization].
Topics: Adenosine; Adenosine Deaminase; Blood; Cells, Cultured; Culture Media; Drosophila melanogaster; Hypoxanthines; Inosine | 1975 |
A specific adenosine phosphorylase, distinct from purine nucleoside phosphorylase.
Topics: Adenosine; Ammonium Sulfate; Bacillus subtilis; Chromatography, Gel; Guanosine; Inosine; Kinetics; Pentosyltransferases; Purine-Nucleoside Phosphorylase | 1976 |
Nucleoside auxotrophy in Drosophila: an autosomal locus yielding mutants supplementable by purine and pyrimidine ribonucleosides.
Topics: Adenosine; Alleles; Animals; Crosses, Genetic; Cytidine; Drosophila melanogaster; Female; Guanosine; Inosine; Male; Mutation; Phenotype; Phosphoribosyl Pyrophosphate; Ribonucleosides; RNA; Uridine | 1976 |
Adenosine metabolism in permanent lymphocyte lines and in erythrocytes of patients with the Lesch-Nyhan syndrome.
Topics: Adenosine; Cell Line; Child; Erythrocytes; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Lymphocytes; Purine Nucleotides | 1977 |
Adenine and adenosine metabolism in phytohemagglutinin (PHA) - stimulated and unstimulated normal human lymphocytes.
Topics: Adenine; Adenine Nucleotides; Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Humans; Hypoxanthines; Inosine; Lectins; Lymphocyte Activation; Lymphocytes | 1977 |
Adenine and adenosine metabolism in lymphocytes deficient in adenosine deaminase (ADA) activity.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Humans; Hypoxanthines; Immunologic Deficiency Syndromes; Inosine; Lymphocytes; Nucleoside Deaminases | 1977 |
High-performance liquid chromatographic separation and quantitation of nucleosides in urine and some other biological fluids.
Topics: Adenosine; Amniotic Fluid; Chromatography, High Pressure Liquid; Colonic Neoplasms; Evaluation Studies as Topic; Female; Guanosine; Humans; Inosine; Nucleosides; Pregnancy; Pseudouridine; Ribonucleosides | 1977 |
Adenine nucleotides and nucleosides in chick embryo ventricles.
Topics: Adenine Nucleotides; Adenosine; Age Factors; Animals; Chick Embryo; Energy Metabolism; Heart; Hypoxanthines; Inosine; Myocardium | 1977 |
Formation of adenosine nucleotide derivatives in isolated hog carotid artery strips.
Topics: Adenosine; Animals; Carotid Arteries; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Muscle, Smooth; Potassium; Swine | 1977 |
Nucleoside transport in inosine-permeable and impermeable sheep erythrocytes [proceedings].
Topics: Adenosine; Animals; Biological Transport; Erythrocytes; Inosine; Sheep | 1977 |
Sephadex-induced reduction of coronary flow in the isolated rat heart: a model for ischemic heart disease.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Coronary Disease; Disease Models, Animal; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Male; Microspheres; Myocardial Contraction; Myocardium; Perfusion; Phosphocreatine; Polysaccharides; Rats; Sepharose | 1977 |
Evidence for enhanced uptake of ATP by liver and kidney in hemorrhagic shock.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Inosine; Kidney; Liver; Magnesium; Rats; Shock, Hemorrhagic | 1977 |
Adenosine uptake by the isolated epithelium of guine pig jejunum.
Topics: Adenine; Adenosine; Animals; Biological Transport; Depression, Chemical; Diffusion; Epithelium; Female; Guanosine; Guinea Pigs; Hexobendine; Hypoxanthines; Inosine; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Male; Thionucleosides | 1977 |
Salvage of adenosine, inosine, hypoxanthine, and adenisine by the isolated epithelium of guinea pig jejunum.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Epithelium; Female; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Intestinal Mucosa; Jejunum; Male; Purines | 1977 |
Adenosine and active hyperemia in dog skeletal muscle.
Topics: Adenosine; Animals; Dogs; Hemodynamics; Hyperemia; Hypoxanthines; Inosine; Muscle Contraction; Muscles; Osmolar Concentration; Phosphates; Potassium | 1976 |
Nucleosides of 2-aza-purines--cytotoxicities and activities as substrates for enzymes metabolizing purine nucleosides.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Arabinose; Aza Compounds; Cell Survival; Cells, Cultured; Drug Resistance; Inosine; Kinetics; N-Glycosyl Hydrolases; Purine Nucleosides | 1976 |
Gas-liquid chromatography of nucleosides. Derivatization and chromatography.
Topics: Adenosine; Chromatography, Gas; Chromatography, Liquid; Cytidine; Deoxyribonucleosides; Fluoroacetates; Guanosine; Inosine; Methods; Nucleosides; Ribonucleosides; Thymidine; Trimethylsilyl Compounds; Uridine | 1976 |
Proceedings: Nucleoside transport variation in sheep erythrocytes.
Topics: Adenosine; Animals; Erythrocytes; Inosine; Sheep | 1976 |
Metabolism and metabolic effects of 8-azainosine and 8-azaadenosine.
Topics: Adenosine; Animals; Azaguanine; Cell Line; Chromatography, Thin Layer; Humans; In Vitro Techniques; Inosine; Mice; Orotic Acid; Polynucleotides; Purines; Pyrimidine Nucleotides; Thymidine; Uridine | 1976 |
Evaluation of microparticle chemically bonded reversed-phase packings in the high-pressure liquid chromatographic analysis of nucleosides and their bases.
Topics: Adenosine; Base Sequence; Binding Sites; Cell Extracts; Chromatography, High Pressure Liquid; Cytidine; Evaluation Studies as Topic; Guanosine; Inosine; Microchemistry; Nucleosides; Thymidine; Uridine; Xanthines | 1976 |
A new synthesis of 5'-deoxy-8,5'-cyclo-adenosine and -inosine: conformationally-fixed purine nucleosides (nucleosides and nucleotides. XVI).
Topics: Adenosine; Inosine; Methods; Nucleic Acid Conformation; Nucleosides | 1976 |
Nucleoside-3'-phosphotriesters as key intermediates for the oligoribonucleotide synthesis. III. An improved preparation of nucleoside 3'-phosphotriesters, their 1H NMR characterization and new conditions for removal of 2-cyanoethyl group.
Topics: Adenosine; Inosine; Magnetic Resonance Spectroscopy; Methods; Nucleotides; Oligonucleotides; Oligoribonucleotides; Uridine | 1976 |
Effect of ischemia and infarction on regional content of adenine nucleotides and derivatives in canine left ventricle.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Disease; Dogs; Female; Heart Ventricles; Hypoxanthines; Inosine; Male; Myocardial Infarction; Myocardium | 1976 |
Endogenously released adenine derivatives: a possible role in epileptogenesis.
Topics: Adenine; Adenosine; Animals; Hypoxanthines; Inosine; Rats; Seizures | 1976 |
Inhibition by nitrobenzylthioinosine of uptake of adenosine, 2'-deoxyadenosine and 9-beta-D-arabinofuranosyladenine by human and mouse erythrocytes.
Topics: Adenosine; Animals; Biological Transport; Deoxyadenosines; Depression, Chemical; Erythrocytes; Humans; In Vitro Techniques; Inosine; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Purine Nucleosides; Thioinosine; Time Factors; Vidarabine | 1975 |
The reversal of methotrexate cytotoxicity to mouse bone marrow cells by leucovorin and nucleosides.
Topics: Adenosine; Animals; Cell Division; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Granulocytes; Guanosine; Hematopoietic Stem Cells; Inosine; Leucovorin; Leukocytes; Male; Methotrexate; Mice; Mice, Inbred C57BL; Ribonucleosides; Thymidine | 1976 |
Detailed purine salvage metabolism in and outside the free malarial parasite.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood; Buffers; Chromatography, Thin Layer; Hypoxanthines; Inosine; Inosine Nucleotides; Mice; Microscopy, Electron, Scanning; Oxidative Phosphorylation; Plasmodium berghei; Purines; Tritium | 1975 |
Comparison of tritiated hypoxanthine, adenine and adenosine for purine-salvage incorporation into nucleic acids of the malarial parasite, Plasmodium berghei.
Topics: Adenine; Adenosine; Allopurinol; Animals; Erythrocytes; Hypoxanthines; Inosine; Inosine Nucleotides; Mice; Nucleic Acids; Plasmodium berghei; Purines | 1975 |
Erythrocyte adenosine deaminase and purine nucleoside phosphorylase activity in gout.
Topics: Adenosine; Aminohydrolases; Body Weight; Erythrocytes; Gout; Humans; Inosine; Kidney Diseases; Pentosyltransferases | 1975 |
Adenosine metabolism in cultured chick-embryo heart cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminophylline; Animals; Carbon Radioisotopes; Cells, Cultured; Chick Embryo; Dipyridamole; Drug Interactions; Hypoxanthines; Inosine; Myocardium; Oxygen | 1975 |
Independent blood-brain barrier transport systems for nucleic acid precursors.
Topics: Adenine; Adenosine; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; DNA; Guanosine; Hypoxanthines; Inosine; Kinetics; Purines; Pyrimidines; Rats; RNA; Uridine | 1975 |
Proceedings: Salvage of adenosine, inosine and hypoxanthine by the isolated intestinal mucosa of guinea pig.
Topics: Adenosine; Animals; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Intestinal Mucosa; Jejunum | 1975 |
Effects of ethyl adenosine-5'-carboxylate on the heart and coronary circulation.
Topics: Adenosine; Aminophylline; Animals; Blood Pressure; Carboxylic Acids; Cardiac Output; Coronary Circulation; Dipyridamole; Dogs; Drug Synergism; Female; Heart Rate; In Vitro Techniques; Inosine; Male | 1975 |
Inhibitors of nucleoside transport. A structure-activity study using human erythrocytes.
Topics: Adenosine; Biological Transport; Chromatography, Paper; Depression, Chemical; Erythrocytes; Humans; Inosine; Mercaptopurine; Nucleosides; Purine Nucleosides; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thioguanine | 1975 |
Metabolic co-operation between biochemically variant hamster cells and heterokaryons formed between these cells and chick erythrocytes.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Cell Fusion; Cell Line; Cell Nucleus; Erythrocytes; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine | 1975 |
Function of 5'-nucleotidase in the uptake of adenosine from AMP by human lymphocytes.
Topics: Adenosine; Adenosine Monophosphate; Biological Transport, Active; Borates; Cyanides; Fluorides; Humans; Inosine; Iodoacetates; Kinetics; Lymphocytes; Nucleotidases | 1975 |
Inhibition of mitogen mediated lymphocyte blastogenesis by adenosine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Humans; Inosine; Lymphocyte Activation; Mitogens | 1975 |
[Comparative study of adenosine and inosine as corrigents of ACD (Acid Citrate Dextrose) solution in preservation of human blood].
Topics: Adenosine; Blood Preservation; Citrates; Glucose; Glycolysis; Humans; Inosine; Solutions | 1975 |
Conformation of the common purine (beta) ribosides in solution: further evidence for a correlation between N-S state of the ribose moiety and syn-anti equilibrium.
Topics: Adenosine; Chemical Phenomena; Chemistry, Physical; Guanosine; Inosine; Magnetic Resonance Spectroscopy; Molecular Conformation; Ribose | 1975 |
The potentiation of the activity of adenosine on coronary blood flow, blood pressure and heart rate by inosine in the dog.
Topics: Adenosine; Animals; Blood Pressure; Coronary Circulation; Dogs; Drug Synergism; Female; Heart Rate; Inosine; Male; Stimulation, Chemical | 1975 |
Effect of adenosine on myocardial oxygen balance.
Topics: Adenosine; Adenosine Monophosphate; Animals; Coronary Circulation; Dogs; Female; Heart Rate; Hypoxanthines; Inosine; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Theophylline; Ventricular Fibrillation | 1976 |
The postanoxic regeneration of 5'-adenosine nucleotides in rabbit kidney tissue during in vitro perfusion.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Hypoxanthines; Hypoxia; Inosine; Kidney; Male; Organ Preservation; Perfusion; Purines; Rabbits; Regeneration; Ribose | 1976 |
A rapid, sensitive assay for adenosine deaminase.
Topics: Adenosine; Adenosine Deaminase; Animals; Chromatography, Ion Exchange; Inosine; Kinetics; Methods; Mice; Microchemistry; Nucleoside Deaminases; Thymus Gland; Time Factors | 1976 |
Modulation of double-stranded RNAs in vivo by RNA duplex unwindase.
Topics: Adenosine; Animals; Cell Compartmentation; Cell Nucleus; Cloning, Molecular; Deamination; Genes, Viral; Inosine; Mutation; Nucleic Acid Conformation; RNA Editing; RNA Helicases; RNA Nucleotidyltransferases; RNA Viruses; RNA, Antisense; RNA, Double-Stranded | 1992 |
Effect of adenosine and inosine on carbon tetrachloride-induced liver damage in rats.
Topics: Adenosine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; gamma-Glutamyltransferase; Hemorrhage; Inosine; Liver; Liver Diseases; Male; Rats; Rats, Inbred Strains | 1992 |
The conformational variability of an adenosine.inosine base-pair in a synthetic DNA dodecamer.
Topics: Adenosine; Base Composition; Base Sequence; DNA; Hydrogen Bonding; Hydrogen-Ion Concentration; Inosine; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; X-Ray Diffraction | 1992 |
Effect of adenosine deaminase on cardiac interstitial adenosine.
Topics: Adenosine; Adenosine Deaminase; Animals; Endocardium; Extracellular Space; Guinea Pigs; In Vitro Techniques; Inosine; Male; Myocardium; Pericardium; Veins | 1992 |
Nucleoside transport inhibition mediates lidoflazine-induced cardioprotection during intermittent aortic crossclamping.
Topics: Adenosine; Aminophylline; Animals; Aorta; Biological Transport; Blood Pressure; Cardiac Output; Cardiopulmonary Bypass; Constriction; Coronary Circulation; Dogs; Female; Inosine; Lidoflazine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Premedication; Receptors, Purinergic | 1992 |
Effects of nucleoside transport inhibition on long-term ex vivo preservation of canine hearts.
Topics: Adenine Nucleotides; Adenosine; Animals; Biological Transport; Cardioplegic Solutions; Creatine Kinase; Dogs; Hypoxanthines; In Vitro Techniques; Inosine; Myocardial Reperfusion; Myocardium; Organ Preservation; Piperazines; Purine Nucleosides; Time Factors; Ventricular Function, Left | 1992 |
The nucleotide metabolism in lactate perfused hearts under ischaemic and reperfused conditions.
Topics: Adenosine; Adenosine Triphosphate; Animals; Energy Metabolism; Glucose; Glycogen; Guanosine Triphosphate; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Kinetics; Lactates; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Phosphocreatine; Pyruvates; Rats; Rats, Inbred Lew; Time Factors; Xanthine; Xanthines | 1992 |
Interstitial adenosine with dipyridamole: effect of adenosine receptor blockade and adenosine deaminase.
Topics: Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Dialysis; Dipyridamole; Dogs; Extracellular Space; Female; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Male; Purinergic Antagonists; Theophylline | 1992 |
The role of the exocyclic amino groups of conserved purines in hammerhead ribozyme cleavage.
Topics: Adenosine; Amines; Base Sequence; Guanosine; Inosine; Molecular Sequence Data; Nucleic Acid Conformation; Purine Nucleosides; Ribonucleosides; RNA, Catalytic; Substrate Specificity | 1992 |
Application of solid-phase extraction on anion-exchange cartridges to quantify 5'-nucleotidase activity.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Chromatography, Ion Exchange; Inosine; Inosine Monophosphate; Myocardium; Rabbits | 1992 |
Purine salvage as a metabolite and energy saving mechanism in the ocular lens.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cattle; Energy Metabolism; Epithelium; Inosine; Lens Capsule, Crystalline; Male; Oxidoreductases; Rats; Rats, Inbred Strains; Transferases | 1992 |
Diadenosine tetraphosphate is co-released with ATP and catecholamines from bovine adrenal medulla.
Topics: Acetylcholine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adrenal Medulla; Animals; Calcium; Catecholamines; Cattle; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Inosine; Luciferases; Potassium; Tritium | 1992 |
Nucleoside transporters in Leishmania major: diversity in adenosine transporter expression or function in different strains.
Topics: Adenosine; Animals; Biological Transport, Active; Carrier Proteins; Deoxyadenosines; Guanosine; Inosine; Leishmania tropica; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Tubercidin | 1992 |
Successful transplantation after long-term preservation of dog hearts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Heart; Heart Transplantation; Inosine; Myocardial Reperfusion Injury; Myocardium; Organ Preservation; Piperazines; Time Factors | 1992 |
Beta-adrenergic stimulation of adenine nucleotide catabolism and purine release in human adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adipose Tissue; Cells, Cultured; Cyclic AMP; Female; Humans; Hypoxanthine; Hypoxanthines; Inosine; Isoproterenol; Kinetics; Lipolysis; Propranolol; Receptors, Adrenergic, beta | 1990 |
Inosine/pyruvate/phosphate medium but not adenosine/pyruvate/phosphate medium introduces millimolar amounts of 5-phosphoribosyl 1-pyrophosphate in human erythrocytes. A 31P-n.m.r. study.
Topics: Adenosine; Culture Media; Erythrocytes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Magnetic Resonance Spectroscopy; Nucleotides; Pentosephosphates; Phosphoribosyl Pyrophosphate | 1990 |
Intravenous adenosine but not its first metabolite inosine provokes chest pain in healthy volunteers.
Topics: Adenosine; Adult; Chest Pain; Dose-Response Relationship, Drug; Electrocardiography; Heart Block; Humans; Injections, Intravenous; Inosine; Male; Respiration; Sodium Chloride; Spirometry; Tidal Volume | 1990 |
Effects of (R)-deoxycoformycin (pentostatin) on intrauterine nucleoside catabolism and embryo viability in the pregnant mouse.
Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Culture Techniques; Deoxyadenosines; Embryonic and Fetal Development; Female; Fetal Death; Fetal Resorption; Fetal Viability; Homeostasis; Inosine; Male; Mice; Mice, Inbred ICR; Pentostatin; Pregnancy; Purine Nucleosides; Stereoisomerism; Teratogens | 1992 |
Purine metabolites and pyrimidine bases in cerebrospinal fluid of children with simple febrile seizures.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Child, Preschool; Cytosine; Female; Guanine; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Infant; Inosine; Inosine Monophosphate; Male; Purines; Pyrimidine Nucleosides; Seizures, Febrile; Thymine; Uracil; Uric Acid; Xanthine; Xanthines | 1991 |
The mechanism of adenosine to inosine conversion by the double-stranded RNA unwinding/modifying activity: a high-performance liquid chromatography-mass spectrometry analysis.
Topics: Adenosine; Coformycin; Deamination; Gas Chromatography-Mass Spectrometry; Hydrolysis; Inosine; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oxygen; RNA, Double-Stranded; Water | 1991 |
Cellular source and role of adenosine in isoproterenol-induced coronary vasodilatation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Hypoxanthine; Hypoxanthines; Inosine; Isoproterenol; Male; Myocardium; Oxygen Consumption; Phosphorylation; Rats; Rats, Inbred Strains; Vasodilation; Xanthine; Xanthines | 1991 |
Endogenous adenosine is an autacoid feedback inhibitor of chloride transport in the shark rectal gland.
Topics: Adenosine; Adenosine Deaminase; Animals; Biological Transport; Chlorides; Colforsin; Dogfish; Feedback; In Vitro Techniques; Inosine; Male; Salt Gland; Theophylline; Thioinosine | 1991 |
Cardioprotective effects of nucleoside transport inhibition in rabbit hearts.
Topics: Adenosine; Animals; Cardiac Output; Coronary Circulation; Inosine; Myocardial Reperfusion Injury; Myocardium; Piperazines; Rabbits | 1991 |
New possibilities in the therapy of immunodeficiency diseases.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; Severe Combined Immunodeficiency | 1991 |
Nucleotide status in erythrocytes of rats infected with Plasmodium berghei.
Topics: Adenine Nucleotides; Adenosine; Animals; Erythrocytes; Guanine Nucleotides; Hemolysis; Hypoxanthine; Hypoxanthines; Inosine; Malaria; Plasmodium berghei; Purine Nucleotides; Rats; Uracil Nucleotides | 1991 |
Regulation of adenosine concentrations by acadesine (AICA-riboside) in human B-lymphoblasts.
Topics: Adenosine; Adenosine Triphosphate; Aminoimidazole Carboxamide; B-Lymphocytes; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Ribonucleosides | 1991 |
Preservation of adenine nucleotides following ischemia and reperfusion: correlation with functional recovery.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Cardioplegic Solutions; Coronary Disease; Female; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Male; Myocardium; Reperfusion; Swine | 1991 |
Preservation of nucleotide pool during heart transplantation and evaluation of adenylate catabolic pathways in the human heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Heart Transplantation; Heart-Lung Transplantation; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Myocardium; Reperfusion; Time Factors | 1991 |
Initial rate measurements of cellular nucleoside transport: time course, initial curvature of time curves and metabolism.
Topics: Adenosine; Amoeba; Animals; Biological Transport; Inosine; Kinetics; Leishmania donovani; Nucleosides; Thymidine; Time Factors; Uridine | 1991 |
Active transport of adenosine into primary cultures of brain cells and its methodological consequences.
Topics: Adenine Nucleotides; Adenosine; Animals; Biological Transport, Active; Brain; Cells, Cultured; Cerebral Cortex; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Neurons; Pentostatin | 1991 |
Adenine nucleotide degradation in cultured chick heart muscle cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Dipyridamole; Glycolysis; Inosine; Myocardium; Oxidative Phosphorylation; Phosphorylation; Thioinosine | 1991 |
5-Amino-4-imidazolecarboxamide riboside raises adenosine in perfused hypoxic rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Cardiac Output; Coronary Circulation; Heart; Hypoxia; Inosine; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Ribonucleosides | 1991 |
Endogenous adenosine release from hippocampal slices: excitatory amino acid agonists stimulate release, antagonists reduce the electrically-evoked release.
Topics: Adenosine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Electric Stimulation; Hippocampus; Inosine; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Effect of exogenous adenosine deaminase on arrhythmias and the release of adenine nucleotide catabolites in isolated rat hearts with coronary occlusion and reperfusion.
Topics: Adenosine; Adenosine Deaminase; Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Heart; Inosine; Male; Myocardial Reperfusion; Rats; Rats, Inbred Strains | 1991 |
Mediation by adenosine of the trophic effects exerted by the sympathetic innervation of blood vessels.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Inosine; Muscle Denervation; Muscle, Smooth, Vascular; Norepinephrine; Oxidopamine; Purinergic Antagonists; Receptors, Purinergic; Reference Values; Saphenous Vein; Sympathectomy; Sympathectomy, Chemical; Vasodilator Agents; Xanthines | 1991 |
Plasma adenosine changes during cardiac surgery.
Topics: Adenosine; Anesthesia, Intravenous; Aortic Valve; Arteries; Coronary Artery Bypass; Fentanyl; Heart Valve Prosthesis; Humans; Inosine; Mitral Valve; Sufentanil; Veins | 1991 |
Contamination of adenosine deaminase by superoxide dismutase. Stabilization of endothelium-derived relaxing factor.
Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Cyclic GMP; Drug Contamination; Endothelium, Vascular; Inosine; Muscle, Smooth, Vascular; Nitric Oxide; Superoxide Dismutase | 1991 |
Acid-base properties of nucleosides and nucleotides as a function of concentration. Comparison of the proton affinity of the nucleic base residues in the monomeric and self-associated, oligomeric 5'-triphosphates of inosine (ITP), guanosine (GTP), and ade
Topics: Adenosine; Adenosine Triphosphate; Guanosine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Inosine; Inosine Triphosphate; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation | 1991 |
Mechanism of peroxide-induced cellular injury in cultured adult cardiac myocytes.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Cell Hypoxia; Chromatography, High Pressure Liquid; Glutathione; Heart; Inosine; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Oxidative Phosphorylation; Peroxides; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains | 1991 |
Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport, Active; Corpus Striatum; Dipyridamole; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Male; Pentostatin; Rats; Rats, Inbred Strains | 1991 |
Influence of hyperglycemia on cerebral adenosine production during ischemia and reperfusion.
Topics: Adenine Nucleotides; Adenosine; Animals; Brain; Brain Ischemia; Hyperglycemia; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Inbred Strains; Reperfusion | 1991 |
Effects of graded perfusion and isovolumic work on epicardial and venous adenosine and cytosolic metabolism.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Cytosol; Extracellular Space; Guinea Pigs; Hemodynamics; Hypoxanthines; Inosine; Kinetics; Magnetic Resonance Spectroscopy; Male; Myocardium; Perfusion; Purines; Veins | 1991 |
[Does vascular endothelium have different transport systems for adenosine and inosine?].
Topics: Adenosine; Adenosine Deaminase; Animals; Biological Transport, Active; Cattle; Cells, Cultured; Cytoplasm; Endothelium, Vascular; Inosine | 1991 |
[The in vivo measurement of ischemic myocardial interstitial metabolites in the beating canine heart: measurement of adenosine using an improved microdialysis technique].
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Coronary Disease; Dialysis; Dogs; Female; Hypoxanthine; Hypoxanthines; Inosine; Male; Microchemistry; Myocardium | 1991 |
Adenosinergic inhibition in hippocampus is mediated by adenosine A1 receptors very similar to those of peripheral tissues.
Topics: Adenosine; Adenosine Deaminase; Animals; Evoked Potentials; Guinea Pigs; Hippocampus; Inosine; Kinetics; Purinergic Antagonists; Xanthines | 1991 |
Tat-dependent adenosine-to-inosine modification of wild-type transactivation response RNA.
Topics: Adenosine; Animals; Base Sequence; Cell Nucleus; Gene Products, tat; HIV-1; Hydrogen Bonding; In Vitro Techniques; Inosine; Molecular Sequence Data; Molecular Structure; Oocytes; RNA, Viral; Structure-Activity Relationship; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation; Xenopus laevis | 1991 |
Leishmania donovani: characteristics of adenosine and inosine transporters in promastigotes of two different strains.
Topics: Adenosine; Animals; Biological Transport; Diffusion; Dilazep; Inosine; Kinetics; Leishmania donovani; Nucleosides; Thioinosine; Thymidine; Uridine | 1991 |
Metabolism of extracellular adenine nucleotides by cultured rat brain astrocytes.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Inosine; Inosine Monophosphate; Kinetics; Rats; Rats, Inbred Strains | 1991 |
The limits of cardiac preservation with University of Wisconsin solution.
Topics: Adenine Nucleotides; Adenosine; Cells, Cultured; DNA; Humans; Hypoxanthine; Hypoxanthines; Inosine; Myocardium; Organ Preservation; Solutions | 1991 |
Transition-state analysis of nucleoside hydrolase from Crithidia fasciculata.
Topics: Adenosine; Animals; Carbon Radioisotopes; Crithidia fasciculata; Deuterium; Hydrolysis; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Molecular Structure; N-Glycosyl Hydrolases; Nitrogen Radioisotopes; Solvents; Tritium | 1991 |
Adenosine release and changes in pial arteriolar diameter during transient cerebral ischemia and reperfusion.
Topics: Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Hypoxanthine; Hypoxanthines; Inosine; Ischemic Attack, Transient; Male; Pia Mater; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Effects of hypothermic ischemia on purine catabolism in canine, primate, and human myocardium.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Heart Arrest, Induced; Heart Transplantation; Humans; Hypothermia, Induced; Inosine; Myocardium; Papio; Phosphocreatine; Purines; Species Specificity; Xanthines | 1991 |
Evaluation of solutions for small intestinal preservation. Biochemical changes as a function of storage time.
Topics: Adenine Nucleotides; Adenosine; Allopurinol; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Glutathione; Hypertonic Solutions; Inosine; Insulin; Male; Organ Preservation; Organ Preservation Solutions; Preservatives, Pharmaceutical; Raffinose; Rats; Rats, Inbred Strains; Sodium Chloride; Solutions; Time Factors | 1991 |
Transmural distribution of extracellular purines in isolated guinea pig heart.
Topics: Adenosine; Adenosine Monophosphate; Animals; Coronary Circulation; Guinea Pigs; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Kinetics; Male; Myocardium; Oxygen Consumption; Perfusion; Purines; Vascular Resistance | 1991 |
Adenosine formation and energy status during hypoperfusion and 2-deoxyglucose infusion.
Topics: Adenosine; Adenosine Monophosphate; Animals; Coronary Circulation; Cytosol; Deoxyglucose; Energy Metabolism; Guinea Pigs; Heart; Inosine; Magnesium; Male; Myocardium; Norepinephrine; Oxygen Consumption; Perfusion; Phosphates | 1991 |
Adenosine deaminase and adenosine attenuate ventricular arrhythmias caused by norepinephrine.
Topics: Adenosine; Adenosine Deaminase; Ammonia; Animals; Arrhythmias, Cardiac; Coronary Vessels; Dogs; Female; Heart Ventricles; Inosine; Male; Norepinephrine; Sodium Chloride | 1991 |
Rapid effects of hypoxia on the cerebrospinal fluid levels of adenosine and related metabolites in newborn and one-month-old piglets.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Blood Gas Analysis; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Swine | 1991 |
The role of adenosine in the vascular adaptation of neonatal cerebral blood flow during hypotension.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Blood Flow Velocity; Brain; Cerebrovascular Circulation; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Oxygen; Receptors, Purinergic; Swine; Theophylline; Vascular Resistance | 1991 |
Developmental regulation of covalent modification of double-stranded RNA during silkmoth oogenesis.
Topics: Adenosine; Animals; Biological Factors; Bombyx; Cell Nucleus; Cells, Cultured; Cytoplasm; Female; Inosine; Oogenesis; Ovary; RNA, Double-Stranded; Substrate Specificity | 1991 |
Quantitation of adenosine, inosine and hypoxanthine in biological samples by microbore-column isocratic high-performance liquid chromatography.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Inosine; Kidney Medulla; Male; Oxygen; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet | 1991 |
Purine agonists prevent trophic changes caused by sympathetic denervation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Hydroxydopamines; Inosine; Norepinephrine; Oxidopamine; Saphenous Vein; Sympathectomy; Sympathectomy, Chemical | 1990 |
Activation of Na+/Ca2+ exchange by adenosine in ewe heart sarcolemma is mediated by a pertussis toxin-sensitive G protein.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Calcium; Female; GTP-Binding Proteins; Guanosine; Heart Ventricles; Inosine; Kinetics; Myocardium; Pertussis Toxin; Phenylisopropyladenosine; Sarcolemma; Sheep; Sodium; Virulence Factors, Bordetella | 1990 |
Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents.
Topics: Adenosine; Animals; Cell Division; Chemical Phenomena; Chemistry; Cytotoxicity, Immunologic; DNA; Guanosine; Immunotherapy; Inosine; Killer Cells, Natural; Lymphoma; Mice; Molecular Structure; Pyrimidine Nucleosides; Ribonucleosides; Semliki forest virus; Spleen; T-Lymphocytes; Togaviridae Infections; Tumor Cells, Cultured | 1990 |
Mechanisms leading to adenosine-stimulated proliferation of microvascular endothelial cells.
Topics: Adenosine; Animals; Biomechanical Phenomena; Cell Division; Cyclic AMP; Dideoxyadenosine; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypoxanthine; Hypoxanthines; Inosine; Isomerism; Microcirculation; Molecular Weight; Thioinosine | 1990 |
Increased myocardial adenosine production and reduction of beta-adrenergic contractile response in aged hearts.
Topics: Adenosine; Aging; Animals; Calcium; Coronary Vessels; Guinea Pigs; Inosine; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardium; Osmolar Concentration; Oxygen Consumption; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Veins | 1990 |
Effect of adenosine and inosine administration on platelet function in rabbits.
Topics: Adenosine; Animals; Aspirin; Blood Platelets; Cyclic AMP; Female; Inosine; Male; Platelet Adhesiveness; Platelet Aggregation; Platelet Function Tests; Rabbits | 1990 |
Purine levels and metabolism in human follicular fluid.
Topics: Adenine; Adenosine; Adult; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Cyclic AMP; Female; Follicular Fluid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Menotropins; Oocytes; Ovary; Purines | 1990 |
Is adenosine a second metabolic substrate for human red blood cells?
Topics: Adenosine; Adenosine Triphosphate; Blood Glucose; Erythrocytes; Glycolysis; Hematocrit; Humans; In Vitro Techniques; Inosine; Kinetics; Lactates; Phosphates | 1990 |
Interstitial transudate purines in normoxic and hypoxic immature and mature rabbit hearts.
Topics: Adenosine; Aging; Animals; Exudates and Transudates; Hemodynamics; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Myocardium; Oxygen Consumption; Rabbits | 1990 |
Effects of nitrous oxide on contractile function and metabolism of the isolated heart.
Topics: Adenosine; Animals; Coronary Circulation; Depression, Chemical; Guinea Pigs; In Vitro Techniques; Inosine; Myocardial Contraction; Myocardium; Nitrous Oxide; Oxygen Consumption | 1990 |
Purines inhibit the development of mouse embryos in vitro.
Topics: Adenosine; Animals; Cell Division; Cells, Cultured; Cleavage Stage, Ovum; Embryonic and Fetal Development; Female; Hypoxanthines; Inosine; Mice; Mice, Inbred Strains; Purines | 1990 |
Role of purine biosynthetic intermediates in response to folate stress in Escherichia coli.
Topics: Adenosine; Aminoimidazole Carboxamide; Bacterial Proteins; Cell Survival; Electrophoresis, Gel, Two-Dimensional; Escherichia coli; Folic Acid; Hemostasis; Inosine; Microbial Sensitivity Tests; Purines; Ribonucleotides; Sulfathiazole; Sulfathiazoles; Trimethoprim | 1990 |
Role of adenosine in regulation of regional cerebral blood flow in sensory cortex.
Topics: Adenosine; Administration, Topical; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Electric Stimulation; Evoked Potentials, Somatosensory; Inosine; Male; Pia Mater; Rats; Rats, Inbred Strains; Sciatic Nerve; Somatosensory Cortex; Theophylline; Vasodilation | 1990 |
[Microdialysis study of release of adenine nucleotide breakdown products into the intercellular space of the myocardium in ischemia and reperfusion].
Topics: Adenine Nucleotides; Adenosine; Animals; Dialysis; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Rats; Rats, Inbred Strains | 1990 |
Pathways of purine metabolism in human adipocytes. Further evidence against a role of adenosine as an endogenous regulator of human fat cell function.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Glycerophosphates; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Isoproterenol; Lipolysis; Pentostatin; Purines; Tubercidin | 1990 |
Tissue release of adenosine triphosphate degradation products during shock in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Diaphragm; Digestive System; Dogs; Hindlimb; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Oxygen; Purine Nucleotides; Renal Circulation; Shock; Xanthine; Xanthines | 1990 |
Adenosine, inosine, and hypoxanthine/xanthine measured in tissue and plasma by a luminescence method.
Topics: Adenosine; Adenosine Deaminase; Animals; Dogs; Humans; Hypoxanthine; Hypoxanthines; Inosine; Luminescent Measurements; Luminol; Pyridazines; Rabbits; Rats; Solutions; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Exogenous adenine nucleotides replete endothelial cell adenosine triphosphate after oxidant injury by adenosine uptake.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Membrane; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Inosine; L-Lactate Dehydrogenase; Oxidation-Reduction; Time Factors; Umbilical Veins | 1990 |
Competition of nucleoside transport inhibitors with binding of 6-[(4-nitrobenzyl)-mercapto]purine ribonucleoside to intact erythrocytes and ghost membranes from different species.
Topics: Adenosine; Animals; Binding, Competitive; Carrier Proteins; Cricetinae; Dilazep; Erythrocyte Membrane; Erythrocytes; Hot Temperature; Humans; Hydrogen-Ion Concentration; Inosine; Membrane Proteins; Mice; Nucleoside Transport Proteins; Piperazines; Rats; Thioinosine | 1990 |
Adenosine metabolism in kidney slices under normoxic conditions.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Chromatography, High Pressure Liquid; Female; Guinea Pigs; In Vitro Techniques; Inosine; Kidney; Oxygen; Pentostatin; Purines | 1990 |
Influence of adenosine on cerebral blood flow during hypoxic hypoxia in the newborn piglet.
Topics: Adenosine; Animals; Animals, Newborn; Arteries; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Hypoxia; Injections, Intraventricular; Inosine; Oxygen; Swine; Theophylline; Vascular Resistance | 1990 |
Biochemical indicators of myocardial ischaemia during coronary artery bypass grafting.
Topics: Adenosine; Cardiopulmonary Bypass; Catecholamines; Coronary Disease; Electrocardiography; Humans; Hypoxanthines; Inosine; Intraoperative Complications; Lactates; Male; Middle Aged; Myocardium; Norepinephrine; Postoperative Complications | 1990 |
All nucleoside transporters in bovine chromaffin cells are nitrobenzylthioinosine sensitive.
Topics: Adenosine; Adrenal Medulla; Animals; Carrier Proteins; Cattle; Cells, Cultured; Dipyridamole; Inosine; Thioinosine | 1990 |
Effect of intracisternally administered adenosine and inosine on apomorphine- and amphetamine-induced stereotyped behaviour in rats.
Topics: Adenosine; Amphetamine; Animals; Apomorphine; Cisterna Magna; Corpus Striatum; Dopamine; Injections; Inosine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra | 1990 |
Interaction of adenine nucleosides in the canine mesenteric circulation.
Topics: Adenosine; Animals; Blood Pressure; Dogs; Inosine; Splanchnic Circulation | 1990 |
Earlier work overlooked.
Topics: Adenosine; Humans; Hypoxanthine; Hypoxanthines; Inosine; Luminescent Measurements; Publishing | 1990 |
[Studies on chemical protectors against radiation. XXVIII. Protective effect of nucleic acid constitutional compounds on radiation damages induced by X-irradiation].
Topics: Adenosine; Animals; Free Radicals; Inosine; Mice; Purine Nucleosides; Radiation Injuries, Experimental | 1990 |
2-Chloroadenosine induction of vagally-mediated and atropine-resistant bronchomotor responses in anaesthetized guinea-pigs.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Anesthesia; Animals; Atropine; Bronchi; Capsaicin; Drug Resistance; Guinea Pigs; Inosine; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Phenylisopropyladenosine; Receptors, Purinergic; Serotonin; Vagus Nerve | 1990 |
Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats.
Topics: Adenosine; Amino Acids; Animals; Body Temperature; Brain Concussion; Cerebral Cortex; Chromatography, High Pressure Liquid; Energy Metabolism; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats | 1990 |
Selective adenosine release from human B but not T lymphoid cell line.
Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; B-Lymphocytes; Cell Line; Deoxyglucose; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Models, Biological; Pentostatin; Rats; T-Lymphocytes; Tubercidin | 1990 |
Inosine transiently decreases coronary flow but potentiates vasodilation by adenosine.
Topics: Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Drug Synergism; In Vitro Techniques; Inosine; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Theophylline; Time Factors; Vasodilation | 1990 |
Transcapillary adenosine transport in isolated guinea pig and rat hearts.
Topics: Adenosine; Animals; Biological Transport; Capillary Permeability; Coronary Vessels; Dipyridamole; Guinea Pigs; Inosine; Male; Models, Cardiovascular; Myocardium; Rats; Rats, Inbred Strains | 1990 |
Sodium-adenosine cotransport in brush-border membranes from rabbit ileum.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Anions; Biological Transport; Epithelium; Ileum; Inosine; Kinetics; Male; Microvilli; Muscle, Smooth; Rabbits; Receptors, Purinergic; Sodium; Uridine | 1990 |
Purine nucleotide metabolism in resident and activated rat macrophages in vitro.
Topics: Adenine; Adenosine; Animals; Cells, Cultured; Guanine; Guanosine; Hypoxanthine; Hypoxanthines; Inosine; Macrophage Activation; Macrophages; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Rats; Thioglycolates | 1985 |
Release of adenosine and its metabolites from activated human leucocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Basophils; Calcimycin; Dose-Response Relationship, Drug; Histamine Release; Humans; Hypoxanthines; Immunoglobulin E; Inosine; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Time Factors | 1986 |
Potentiation by levamisole, methisoprinol, and adenine or adenosine of the inhibitory activity of human interferon against encephalomyocarditis virus.
Topics: Adenine; Adenosine; Drug Synergism; Encephalomyocarditis virus; HeLa Cells; Humans; Inosine; Inosine Pranobex; Interferons; Levamisole; Virus Replication | 1986 |
Cardiac anaphylaxis in isolated guinea pig hearts perfused at constant flow or constant pressure.
Topics: Adenosine; Anaphylaxis; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Guinea Pigs; Heart; Heart Rate; Histamine Release; Immunization, Passive; Inosine; Male; Myocardial Contraction; Perfusion | 1987 |
Protection by bepridil against myocardial ATP-catabolism is probably due to negative inotropy.
Topics: Adenosine; Adenosine Triphosphate; Animals; Bepridil; Depression, Chemical; Energy Metabolism; Heart; Hypoxanthine; Hypoxanthines; Inosine; Male; Myocardium; Pyrrolidines; Rats; Rats, Inbred Strains; Vasodilation; Xanthine; Xanthines | 1987 |
Striatal adenosine levels measured 'in vivo' by microdialysis in rats with unilateral dopamine denervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Denervation; Dialysis; Dopamine; Guanosine; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Hypoxanthine; Hypoxanthines; Inosine; Male; Oxidopamine; Rats; Rats, Inbred Strains | 1987 |
Nucleoside uptake by Trichomonas vaginalis.
Topics: Adenosine; Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cytidine; Dilazep; DNA; Guanosine; Inosine; Kinetics; Nucleosides; RNA; Thioinosine; Thionucleosides; Thymidine; Trichomonas vaginalis; Uridine | 1988 |
Vascular development in chick embryos: a possible role for adenosine.
Topics: Adenosine; Aminophylline; Animals; Cardiovascular System; Chick Embryo; Dipyridamole; Inosine; Neovascularization, Pathologic; Vascular Resistance | 1989 |
IMP production by ATP-depleted adult rat heart cells. Effects of glycolysis and alpha 1-adrenergic stimulation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; AMP Deaminase; Animals; Cells, Cultured; Coformycin; Glycolysis; Heart; Inosine; Inosine Monophosphate; Inosine Nucleotides; Kinetics; Myocardium; NAD; Phenylephrine; Rats; Receptors, Adrenergic, beta; Ribonucleosides | 1989 |
Production of AMP and adenosine in the interstitial fluid compartment of the isolated perfused normoxic guinea pig heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Extracellular Space; Guinea Pigs; Heart; Hydroxydopamines; Inosine; Male; Myocardium; Oxidopamine; Pyrophosphatases; Sympathectomy, Chemical | 1989 |
Adenosine production and energy metabolism in ischaemic and metabolically stimulated rat heart.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Allosteric Regulation; Animals; Coronary Circulation; Coronary Disease; Energy Metabolism; Heart; Hypoxia; Inosine; Isoproterenol; Magnetic Resonance Spectroscopy; Male; Myocardium; Rats; Rats, Inbred Strains | 1989 |
Adenosine, inosine, hypoxanthine, xanthine and uric acid concentrations in the cerebrospinal fluid of unanaesthetized rats.
Topics: Adenosine; Anesthesia; Animals; Hypoxanthines; Inosine; Male; Rats; Rats, Inbred Strains; Uric Acid; Xanthines | 1989 |
Role of adenosine in hypoxic alterations of anaphylaxis of isolated guinea pig hearts.
Topics: Adenosine; Anaphylaxis; Animals; Antigens; Atrioventricular Node; Coronary Circulation; Guinea Pigs; Heart; Hemodynamics; Histamine; Hypoxia; In Vitro Techniques; Inosine; Male; Myocardium; Theophylline; Thromboxanes | 1989 |
Aging increases adenosine and inosine release by human fibroblast cultures.
Topics: Adenosine; Aging; Cells, Cultured; Fibroblasts; Humans; Inosine | 1989 |
"Hormone-like" effect of adenosine and inosine on gluconeogenesis from lactate in isolated hepatocytes.
Topics: Adenosine; Animals; Epinephrine; Glucagon; Gluconeogenesis; In Vitro Techniques; Inosine; Lactates; Liver; Male; Rats; Rats, Inbred Strains | 1989 |
Cholinergic and noradrenergic denervations decrease labelled purine release from electrically stimulated rat cortical slices.
Topics: Adenosine; Adrenergic Fibers; Animals; Basal Ganglia; Cerebral Cortex; Choline O-Acetyltransferase; Cholinergic Fibers; Electric Stimulation; Hypoxanthine; Hypoxanthines; Ibotenic Acid; Inosine; Male; Nerve Degeneration; Purines; Rats; Rats, Inbred Strains | 1989 |
Synthesis of 8-diamino-substituted adenosine, inosine, and guanosine.
Topics: Adenosine; Diamines; Guanosine; Inosine | 1989 |
Relationship between extracellular and intracellular nucleotide metabolism in human lymphocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; B-Lymphocytes; Dose-Response Relationship, Drug; Extracellular Space; Humans; Inosine; Purines; T-Lymphocytes | 1989 |
[Transport of adenosine across the endothelium of the isolated perfused rat aorta].
Topics: Adenosine; Animals; Aorta; Biological Transport, Active; Culture Techniques; Endothelium, Vascular; Inosine; Muscle, Smooth, Vascular; Perfusion; Rats | 1989 |
[The pool of free purine and pyrimidine nucleosides and bases in the thymocytes, and splenic T- and B-lymphocytes of C3HA mice during the growth of solid hepatoma 22a].
Topics: Adenine; Adenosine; Animals; B-Lymphocytes; Deoxycytidine; DNA, Neoplasm; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Liver Neoplasms, Experimental; Mice; Mice, Inbred C3H; Purine Nucleosides; Pyrimidine Nucleosides; Spleen; T-Lymphocytes; Thymus Gland; Time Factors; Xanthine; Xanthines | 1989 |
A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs.
Topics: Adenosine; Animals; Base Composition; Cell Line; DNA; Humans; Inosine; Nucleic Acid Conformation; Xenopus laevis | 1989 |
Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Circulation; Extracellular Space; Hypertension; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Lactates; Lactic Acid; Male; Rats; Rats, Inbred SHR; Xanthine; Xanthines | 1989 |
Transendothelial transport and metabolism of adenosine and inosine in the intact rat aorta.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Endothelium, Vascular; Female; Inosine; Male; Muscle, Smooth, Vascular; Purines; Rats; Rats, Inbred Strains; Tritium | 1989 |
Adenylate degradation products release from the human myocardium during open heart surgery.
Topics: Adenosine; Aortic Valve; Cardiac Surgical Procedures; Cardioplegic Solutions; Cardiopulmonary Bypass; Chromatography, High Pressure Liquid; Heart Defects, Congenital; Humans; Hypoxanthine; Hypoxanthines; Inosine; Mitral Valve; Myocardium; Purines; Xanthine Dehydrogenase | 1989 |
Biochemical and functional effects of nucleoside transport inhibition in the isolated cat heart.
Topics: Adenine Nucleotides; Adenosine; Animals; Biological Transport; Cardiac Output; Cats; Coronary Circulation; Energy Metabolism; Heart; Heart Rate; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Myocardium; Nucleosides; Perfusion; Phosphates; Phosphocreatine; Piperazines | 1989 |
Passive and carrier-mediated permeation of different nucleosides through the reconstituted nucleoside transporter.
Topics: Adenosine; Blood Proteins; Carrier Proteins; Cell Membrane Permeability; Erythrocyte Membrane; Humans; Inosine; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Uridine | 1989 |
Inhibition of adenosine deaminase activity reveals an intense active transport of adenosine into neurons in primary cultures.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Cells, Cultured; Hypoxanthine; Hypoxanthines; Inosine; Mice; Neurons; Nucleoside Deaminases; Pentostatin | 1989 |
Isocratic separation of ATP and its degradation products from biological fluids by automated liquid chromatography.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Autoanalysis; Body Fluids; Chromatography, Liquid; Cyclic AMP; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Xanthine; Xanthines | 1988 |
Release of purines from postsynaptic structures of amphibian ganglia.
Topics: Action Potentials; Adenine Nucleotides; Adenosine; Animals; Atropine; Carbachol; Electric Stimulation; Ganglia; Hypoxanthine; Hypoxanthines; Inosine; Phosphoric Monoester Hydrolases; Purines; Rana catesbeiana; Synapses; Tubocurarine | 1988 |
Potassium-stimulated purine release by cultured sympathetic neurons.
Topics: Adenine Nucleotides; Adenosine; Animals; Blood; Blood Physiological Phenomena; Calcium; Cells, Cultured; Culture Media; Electrophysiology; Ganglia, Sympathetic; Hypoxanthine; Hypoxanthines; Inosine; Neurons; Neurotransmitter Agents; Potassium; Purines; Rodentia | 1985 |
Maintenance of murine oocyte meiotic arrest: uptake and metabolism of hypoxanthine and adenosine by cumulus cell-enclosed and denuded oocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Biological Transport; Hypoxanthines; IMP Dehydrogenase; Inosine; Meiosis; Mice; Mycophenolic Acid; Oocytes; Ribonucleosides | 1986 |
Blockade of N-methyl-D-aspartate-sensitive acidic amino acid receptors inhibits ischemia-induced accumulation of purine catabolites in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Brain Ischemia; Corpus Striatum; Hypoxanthine; Hypoxanthines; Inosine; Male; Purines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xanthine; Xanthines | 1986 |
Inactivation of the bovine heart mitochondrial F1-ATPase by 5'-p-fluorosulfonylbenzoyl[3H]inosine is accompanied by modification of tyrosine 345 in a single beta subunit.
Topics: Adenosine; Animals; Cattle; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Inosine; Inosine Triphosphatase; Kinetics; Mitochondria, Heart; Peptide Fragments; Proton-Translocating ATPases; Pyrophosphatases; Trypsin; Tyrosine | 1986 |
Evidence for functional heterogeneity among the catalytic sites of the bovine heart mitochondrial F1-ATPase.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Benzofurans; Binding Sites; Cattle; Dinitrofluorobenzene; Hydrolysis; Inosine; Mitochondria, Heart; Proton-Translocating ATPases; Structure-Activity Relationship | 1987 |
Renal vasoconstriction and transient declamp hypotension after infrarenal aortic occlusion: role of plasma purine degradation products.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Aorta, Abdominal; Blood Pressure; Constriction; Dogs; Hypoxanthine; Hypoxanthines; Inosine; Male; Phentolamine; Postoperative Complications; Receptors, Adrenergic, alpha; Renal Circulation; Xanthine; Xanthines | 1988 |
Determination of rat cerebrospinal fluid concentrations of adenosine, inosine, hypoxanthine, xanthine and uric acid by high performance liquid chromatography.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Hypoxanthines; Inosine; Male; Nucleosides; Rats; Rats, Inbred Strains; Uric Acid; Xanthines | 1988 |
Erythrocyte acid phosphatase (ACP1) activity. In vitro modulation by adenosine and inosine and effects of adenosine deaminase (ADA) polymorphism.
Topics: Acid Phosphatase; Adenosine; Adenosine Deaminase; Erythrocytes; Genotype; Humans; In Vitro Techniques; Inosine; Nucleoside Deaminases; Phenotype; Polymorphism, Genetic | 1989 |
Effect of inosine on pial arterioles: potentiation of adenosine-induced vasodilation.
Topics: Adenosine; Animals; Arteries; Arterioles; Cerebrovascular Circulation; Drug Synergism; Inosine; Male; Muscle, Smooth, Vascular; Pia Mater; Rats; Rats, Inbred Strains; Theophylline; Vasodilation; Venules | 1989 |
d-Propranolol prevents adenosine formation associated with myocardial hypoperfusion.
Topics: Adenosine; Animals; Blood Pressure; Coronary Circulation; Guinea Pigs; Heart; In Vitro Techniques; Inosine; Male; Myocardium; Oxygen; Oxygen Consumption; Perfusion; Propranolol; Reference Values | 1989 |
A refined method for the photoaffinity labelling of the nitrobenzylthioinosine-sensitive nucleoside transport protein: application to cell membranes of calf lung tissue.
Topics: Adenosine; Affinity Labels; Animals; Carrier Proteins; Cattle; Cell Membrane; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Inosine; Lung; Membrane Proteins; Nucleoside Transport Proteins; Photochemistry; Thioinosine | 1989 |
Evidence suggesting an Ra-type adenosine receptor in bovine coronary arteries.
Topics: Adenosine; Adenosine Deaminase; Animals; Cattle; Coronary Vessels; Inosine; Pentosyltransferases; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Characterization of nitrobenzylthioinosine binding to nucleoside transport sites selective for adenosine in rat brain.
Topics: Adenosine; Animals; Binding Sites; Binding, Competitive; Brain; Inosine; Male; Nucleosides; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Thioinosine; Time Factors; Tritium | 1985 |
Localization of [3H]cyclohexyladenosine and [3H]nitrobenzylthioinosine binding sites in rat striatum and superior colliculus.
Topics: Adenosine; Animals; Binding Sites; Corpus Striatum; Inosine; Kainic Acid; Male; Ophthalmologic Surgical Procedures; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Superior Colliculi; Thioinosine | 1986 |
Adenosine metabolism in microvessels from heart and brain.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Animals; Capillaries; Cerebrovascular Circulation; Coronary Vessels; Heart Ventricles; Inosine; Kinetics; Nucleotidases; Rabbits; Rats; S-Adenosylhomocysteine | 1986 |
OH-induced free radicals in purine nucleosides and their homopolymers: e.s.r. and spin-trapping with 2-methyl-2-nitrosopropane.
Topics: Adenosine; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; Electron Spin Resonance Spectroscopy; Guanosine; Hydroxides; Hydroxyl Radical; Inosine; Nitroso Compounds; Poly A; Poly I; Purine Nucleosides | 1986 |
Kinetics of the 5'-nucleotidase and the adenosine deaminase in subcellular fractions of rat brain.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Animals; Brain; Catalysis; Inosine; Kinetics; Male; Nucleoside Deaminases; Nucleotidases; Rats; Rats, Inbred Strains; Subcellular Fractions; Suspensions | 1986 |
Uptake and metabolism of [3H]adenosine by Aplysia ganglia and by individual neurons.
Topics: Adenine Nucleotides; Adenosine; Animals; Aplysia; Chromatography, High Pressure Liquid; Cyclic AMP; Ganglia; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Neurons; Tissue Distribution; Uric Acid | 1986 |
The disappearance of adenosine from blood and platelet suspension in relation to the platelet cyclic AMP content.
Topics: Adenosine; Adenosine Deaminase; Blood Platelets; Cyclic AMP; Half-Life; Inosine | 1987 |
Nucleoside uptake in Trypanosoma cruzi: analysis of a mutant resistant to tubercidin.
Topics: Adenosine; Aminoglycosides; Animals; Anti-Bacterial Agents; Biological Transport; Cloning, Molecular; Drug Resistance; Inosine; Mutation; Nucleosides; Purines; Pyrimidines; Thymidine; Trypanosoma cruzi; Tubercidin; Uridine; Valine | 1988 |
Adenosine accumulation in Saccharomyces cerevisiae cultured in medium containing low levels of adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Aspergillus; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Inosine; Models, Chemical; Purine-Nucleoside Phosphorylase; Saccharomyces cerevisiae | 1986 |
Cytosolic adenylates and adenosine release in perfused working heart. Comparison of whole tissue with cytosolic non-aqueous fractionation analyses.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Dioxide; Cytosol; Energy Metabolism; Guinea Pigs; Hydrogen-Ion Concentration; Inosine; Male; Myocardium; Oxygen Consumption; Phosphates; Phosphocreatine; Phosphorylation | 1986 |
The pH dependence of spectral parameters for Kalckar's adenosine deaminase assay.
Topics: Adenosine; Adenosine Deaminase; Bacillus cereus; Hydrogen-Ion Concentration; Inosine; Nucleoside Deaminases; Spectrophotometry, Ultraviolet | 1987 |
Inosine and adenosine formation in ischemic and non-ischemic contracting muscles of rats: difference between fast and slow muscles.
Topics: Adenosine; Animals; Electric Stimulation; Inosine; Ischemia; Male; Muscles; Rats; Rats, Inbred Strains | 1988 |
An unwinding activity that covalently modifies its double-stranded RNA substrate.
Topics: Adenosine; Animals; Inosine; Nucleic Acid Conformation; Ribonucleases; RNA, Double-Stranded; Xenopus | 1988 |
Diltiazem and verapamil reduce the loss of adenine nucleotide metabolites from hypoxic hearts.
Topics: Adenine Nucleotides; Adenosine; Animals; Body Water; Calcium; Creatine Kinase; Diltiazem; Female; Heart; Hypoxanthine; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Kinetics; Male; Myocardial Contraction; Myocardium; Perfusion; Rabbits; Reference Values; Verapamil | 1988 |
Ruthenium(III) ion complexes with nucleic acid bases and nucleosides.
Topics: Adenine; Adenosine; Cytosine; Guanine; Guanosine; Inosine; Ruthenium; Ruthenium Compounds; Spectrophotometry; Spectrophotometry, Infrared | 1988 |
[Calcium antagonists and adenosine derivatives in the treatment of patients with chronic ischemic heart disease].
Topics: Adenosine; Aged; Calcium Channel Blockers; Chronic Disease; Coronary Disease; Drug Evaluation; Drug Therapy, Combination; Female; Fendiline; Humans; Inosine; Male; Middle Aged | 1988 |
Effect of adenosine and inosine on experimental myocardial infarction in rats.
Topics: Adenosine; Animals; Female; Inosine; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats | 1988 |
Transport and metabolism of adenosine in the perfused guinea-pig placenta.
Topics: Adenosine; Animals; Biological Transport; Dipyridamole; Female; Guinea Pigs; Hypoxanthine; Hypoxanthines; Inosine; Maternal-Fetal Exchange; Placenta; Pregnancy; Thioinosine; Tritium; Uric Acid | 1988 |
Extracellular nucleotide catabolism in human B and T lymphocytes. The source of adenosine production.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; B-Lymphocytes; Carbon Radioisotopes; Cell Line; Cells, Cultured; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Nucleotides; Palatine Tonsil; T-Lymphocytes; Tritium | 1988 |
Effects of deoxycoformycin on adenosine, inosine, hypoxanthine, xanthine, and uric acid release from the hypoxemic rat cerebral cortex.
Topics: Adenosine; Animals; Cerebral Cortex; Coformycin; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Pentostatin; Rats; Rats, Inbred Strains; Ribonucleosides; Uric Acid; Xanthine; Xanthines | 1988 |
Regulation of lipoprotein lipase immunoreactive mass in isolated human adipocytes.
Topics: Adenosine; Adipose Tissue; Antibody Specificity; Enzyme-Linked Immunosorbent Assay; Humans; Immunosorbent Techniques; Inosine; Insulin; Insulin-Like Growth Factor I; Lipoprotein Lipase; Phenylisopropyladenosine | 1988 |
Nucleotides, nucleosides, and oxypurines in human kidneys measured by use of reversed-phase high-performance liquid chromatography.
Topics: Adenine Nucleotides; Adenosine; Chromatography, High Pressure Liquid; Coenzyme A; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Kidney Cortex; Kidney Transplantation; NAD; NADP; Nucleosides; Nucleotides; Quality Control; Xanthine; Xanthines | 1988 |
Effects of nifedipine and felodipine on adenosine and inosine release from the hypoxemic rat cerebral cortex.
Topics: Adenosine; Animals; Cerebral Cortex; Felodipine; Hypoxia, Brain; Inosine; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains | 1988 |
Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Cells, Cultured; Dipyridamole; Endothelium, Vascular; Glycolysis; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Iodoacetates; Iodoacetic Acid; Male; Oxidative Phosphorylation; Potassium; Sodium; Sodium Cyanide; Swine; Vasodilation | 1988 |
Muscarinic modulation of purine release from electrically stimulated rat cortical slices.
Topics: Adenosine; Animals; Atropine; Cerebral Cortex; Chromatography, High Pressure Liquid; Electric Stimulation; Hypoxanthine; Hypoxanthines; Inosine; Male; Oxotremorine; Purines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tetrodotoxin; Tritium | 1988 |
Purine accumulation in human fat cell suspensions. Evidence that human adipocytes release inosine and hypoxanthine rather than adenosine.
Topics: Adenine Nucleotides; Adenosine; Adipose Tissue; Biological Transport; Cells, Cultured; Dipyridamole; Female; Humans; Hypoxanthine; Hypoxanthines; Inosine; Isoproterenol; Kinetics; Reference Values | 1988 |
Pharmacological characterization of rapidly accumulated adenosine by dissociated brain cells from adult rat.
Topics: Adenosine; Adenosine Monophosphate; Animals; Binding, Competitive; Brain; Dilazep; Dipyridamole; Inosine; Kinetics; Male; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Thioinosine; Uridine | 1988 |
Interstitial transudate concentration of adenosine and inosine in rat and guinea pig hearts.
Topics: Adenosine; Animals; Coformycin; Coronary Circulation; Dipyridamole; Exudates and Transudates; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Inosine; Myocardium; Oxygen Consumption; Perfusion; Rats | 1988 |
Effect of adenosine on histamine release and atrioventricular conduction during guinea pig cardiac anaphylaxis.
Topics: Adenosine; Anaphylaxis; Animals; Antigens; Blood Pressure; Coronary Vessels; Electrocardiography; Guinea Pigs; Heart Block; Heart Conduction System; Heart Diseases; Heart Rate; Histamine; In Vitro Techniques; Inosine; Male; Vascular Resistance | 1988 |
Demonstration of the adenosine reservoirs with nitrobenzylthioinosine in liver and diaphragm by high-performance liquid chromatography.
Topics: Adenine Nucleotides; Adenosine; Animals; Chromatography, High Pressure Liquid; Diaphragm; Inosine; Ischemia; Liver; Male; Rats; Rats, Inbred F344; Respiratory Muscles; Solvents; Spectrophotometry, Ultraviolet; Thioinosine | 1988 |
Modulation of erythropoietin production by adenosine.
Topics: Adenosine; Adenosine Deaminase; Animals; Erythropoietin; Hypoxanthine; Hypoxanthines; Inosine; Kidney; Male; Organ Culture Techniques; Perfusion; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
Adenine nucleotide metabolites are beneficial for recovery of cardiac contractile force after hypoxia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Hypoxanthines; Hypoxia; Inosine; Male; Myocardial Contraction; Myocardium; Phosphocreatine; Rabbits | 1988 |
A reexamination of the effects induced by adenosine and its degradation products on rat fat cell lipolysis.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lipid Mobilization; Norepinephrine; Rats; Theophylline; Uric Acid | 1988 |
Adenosine uptake and [3H]nitrobenzylthioinosine binding in developing rat brain.
Topics: Adenosine; Aging; Animals; Binding Sites; Brain; Cerebellum; Cerebral Cortex; Hypothalamus; Inosine; Male; Rats; Rats, Inbred Strains; Superior Colliculi; Thioinosine | 1987 |
Skeletal muscle adenosine, inosine and hypoxanthine release following ischaemic forearm exercise in myoadenylate deaminase deficiency and McArdle's disease.
Topics: Adenosine; AMP Deaminase; Female; Glycogen Storage Disease; Glycogen Storage Disease Type V; Humans; Hypoxanthine; Hypoxanthines; Inosine; Ischemia; Male; Middle Aged; Muscles; Nucleotide Deaminases; Physical Exertion; Purine Nucleosides | 1986 |
Specificity of 2'-deoxycoformycin inhibition of adenosine metabolism in intact human skin fibroblasts.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Cells, Cultured; Coformycin; Dose-Response Relationship, Drug; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Nucleoside Deaminases; Pentostatin; Phosphorylation; Ribonucleosides; Skin | 1986 |
Biosynthesis of 2'-deoxycoformycin: evidence for ring expansion of the adenine moiety of adenosine to a tetrahydroimidazo[4,5-d][1,3]diazepine system.
Topics: Adenosine; Antineoplastic Agents; Carbon Radioisotopes; Coformycin; Indicators and Reagents; Inosine; Magnetic Resonance Spectroscopy; Pentostatin; Ribonucleosides | 1987 |
Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Inosine; Kinetics; Methacholine Chloride; Methacholine Compounds | 1986 |
Increased brain interstitial fluid adenosine concentration during hypoxia in newborn piglet.
Topics: Adenosine; Animals; Animals, Newborn; Brain Chemistry; Cerebrovascular Circulation; Cisterna Magna; Extracellular Space; Hydrogen; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Potassium; Regional Blood Flow; Swine | 1987 |
Formation and release of purine catabolites during hypoperfusion, anoxia, and ischemia.
Topics: Adenosine; Animals; Biological Transport; Coronary Circulation; Coronary Disease; Hypoxanthine; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Myocardium; Nucleotides; Purines; Rabbits | 1987 |
Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain Chemistry; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Ischemic Attack, Transient; Male; Nucleotides; Purines; Rats; Rats, Inbred Strains; Xanthine; Xanthines | 1987 |
Observations on the energy and redox state and protein synthetic rate in animal and human placentas.
Topics: Adenosine; Adenosine Triphosphate; Animals; Energy Metabolism; Female; Guinea Pigs; Humans; Inosine; Lactates; Lactic Acid; Oxidation-Reduction; Placenta; Pregnancy; Sheep | 1987 |
Nucleoside permeation in mouse erythrocytes infected with Plasmodium yoelii.
Topics: Adenosine; Affinity Labels; Animals; Biological Transport; Erythrocytes; Female; Inosine; Kinetics; Malaria; Mice; Mice, Inbred Strains; Plasmodium; Ribonucleosides; Thioinosine; Tritium; Tubercidin | 1987 |
Myoadenylate deaminase deficiency and forearm ischemic exercise testing.
Topics: Adenosine; Adult; Ammonia; AMP Deaminase; Female; Forearm; Humans; Hypoxanthine; Hypoxanthines; Inosine; Ischemia; Lactates; Male; Middle Aged; Nucleotide Deaminases; Physical Exertion | 1987 |
Chemiluminescent determination of adenosine, inosine, and hypoxanthine/xanthine.
Topics: Adenosine; Adipose Tissue; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Inosine; Luminescent Measurements; Oxidation-Reduction; Uric Acid; Xanthine; Xanthines | 1987 |
Effects of adenosine and theophylline on canine tracheal smooth muscle tone.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Dogs; Drug Interactions; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Theophylline; Trachea | 1987 |
Adenine nucleotide degradation in the human myocardium during cardioplegia.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adult; Aged; Heart Arrest, Induced; Humans; Inosine; Inosine Monophosphate; Middle Aged; Myocardium | 1987 |
Interstitial fluid adenosine and sagittal sinus blood flow during bicuculline-seizures in newborn piglets.
Topics: Adenosine; Animals; Animals, Newborn; Bicuculline; Cerebrovascular Circulation; Cranial Sinuses; Extracellular Space; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Seizures; Swine | 1987 |
Effect of adenosine and inosine on ureagenesis in hepatocytes.
Topics: Adenosine; Ammonia; Animals; Dose-Response Relationship, Drug; Epinephrine; Glucagon; In Vitro Techniques; Inosine; Liver; Male; Rats; Rats, Inbred Strains; Stimulation, Chemical; Urea | 1987 |
Cardiac myocyte guanosine transport and metabolism.
Topics: Adenosine; Animals; Binding, Competitive; Biological Transport; Guanine Nucleotides; Guanosine; Inosine; Kinetics; Male; Myocardium; Phosphorylation; Rats; Rats, Inbred Strains; Thioinosine | 1987 |
Increases in cerebral cortical perfusate adenosine and inosine concentrations during hypoxia and ischemia.
Topics: Adenosine; Animals; Cerebral Cortex; Hypotension; Hypoxia; Inosine; Male; Rats; Rats, Inbred Strains | 1987 |
Possible mechanism by which coenzyme Q10 improves reoxygenation-induced recovery of cardiac contractile force after hypoxia.
Topics: Adenosine; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Coenzymes; Creatine Kinase; Female; Hemodynamics; Inosine; Male; Myocardial Contraction; Myocardium; Oxygen; Perfusion; Phosphocreatine; Rabbits; Ubiquinone | 1987 |
Mononucleotide metabolism in the rat brain after transient ischemia.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Guanine; Guanosine Diphosphate; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Ischemic Attack, Transient; Male; Nucleotides; Phosphocreatine; Rats; Rats, Inbred Strains; Uridine Triphosphate | 1986 |
HPLC determination of adenosine, inosine and hypoxanthine levels in human term placenta.
Topics: Adenosine; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Hypoxanthines; Inosine; Placenta; Pregnancy; Pregnancy Trimester, Third | 1986 |
Endogenous adenosine inhibits catecholamine contractile responses in normoxic hearts.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Pressure; Catecholamines; Drug Synergism; Heart Ventricles; In Vitro Techniques; Inosine; Isoproterenol; Male; Myocardial Contraction; Phenylisopropyladenosine; Rats; Rats, Inbred Strains | 1986 |
Myocardial adenosine cycling rates during normoxia and under conditions of stimulated purine release.
Topics: Acetates; Acetic Acid; Adenosine; Animals; In Vitro Techniques; Inosine; Male; Myocardium; Oxygen; Purines; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tubercidin; Uric Acid | 1986 |
Effects of three purine-related compounds on pancreatic exocrine secretion in the dog.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dogs; Dopamine; Female; Inosine; Male; Pancreas; Secretin | 1986 |
Carbocyclic inosine as a potent anti-leishmanial agent: the metabolism and selective cytotoxic effects of carbocyclic inosine in promastigotes of Leishmania tropica and Leishmania donovani.
Topics: Adenosine; Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Inosine; Leishmania donovani; Leishmania tropica; Mice; Trypanocidal Agents | 1986 |
Measurement of adenosine, inosine and hypoxanthine in human term placenta by reversed-phase high-performance liquid chromatography.
Topics: Adenosine; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Hypoxanthines; Inosine; Placenta; Pregnancy; Spectrophotometry, Ultraviolet; Xanthine Oxidase | 1986 |
Increases in cerebral interstitial fluid adenosine concentration during hypoxia, local potassium infusion, and ischemia.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dialysis; Extracellular Space; Hypoxanthine; Hypoxanthines; Hypoxia, Brain; Inosine; Male; Potassium; Rats; Rats, Inbred Strains | 1986 |
Purine salvage in rat heart myoblasts.
Topics: Adenine; Adenosine; Animals; Biological Transport; Hypoxanthine; Hypoxanthines; Inosine; Myocardium; Phosphates; Purine Nucleotides; Purines; Rats | 1986 |
Myoadenylate deaminase deficiency: diagnosis by forearm ischemic exercise testing.
Topics: Adenosine; Adult; Ammonia; AMP Deaminase; Humans; Hypoxanthine; Hypoxanthines; Inosine; Ischemia; Lactates; Nucleotide Deaminases; Physical Exertion; Purine-Pyrimidine Metabolism, Inborn Errors | 1986 |
Effects of ATP-MgCl2 and adenosine-MgCl2 administration on intracellular ATP levels in the kidney.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; In Vitro Techniques; Inosine; Inosine Monophosphate; Kidney; Kinetics; Magnesium; Magnesium Chloride; Male; Perfusion; Rats | 1986 |
Photoaffinity labelling of a nitrobenzylthioinosine-binding polypeptide from cultured Novikoff hepatoma cells.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Biological Transport; Cell Membrane; Cells, Cultured; Dipyridamole; Electrophoresis, Polyacrylamide Gel; Inosine; Liver Neoplasms, Experimental; Neoplasm Proteins; Rats; Thioinosine; Uridine | 1986 |
Two high affinity nucleoside transporters in Leishmania donovani.
Topics: Adenosine; Animals; Biological Transport; Cell Line; Inosine; Kinetics; Leishmania donovani; Membrane Transport Proteins; Nucleosides; Substrate Specificity; Uridine | 1987 |
[Cerebrospinal fluid concentrations of creatinine and purine metabolites determined by high performance liquid chromatography: preliminary report on head injury and stroke patients].
Topics: Adenosine; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Craniocerebral Trauma; Creatinine; Humans; Hypoxanthine; Hypoxanthines; Inosine; Uric Acid | 1987 |
Urinary purines and nucleosides in immune deficiencies.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adult; Child; Deoxyadenosines; Female; Humans; Immunologic Deficiency Syndromes; Inosine; Purine Nucleosides; Purines; Pyrimidine Nucleosides; Pyrimidines; S-Adenosylhomocysteine; Thionucleosides | 1985 |
Antagonism of the positive chronotropic effect of norepinephrine by purine nucleosides in rat atria.
Topics: Adenine; Adenosine; Animals; Deoxyadenosines; Heart Atria; Heart Rate; Inosine; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1985 |
[Characteristics of adenosine activity on adenine nucleotide metabolism of rat thymocytes].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport; Coformycin; Inosine; Inosine Monophosphate; Pentostatin; Rats; Rats, Inbred Strains; Thymus Gland | 1985 |
Genetic analysis of the 6-thiobenzylpurine binding site of the nucleoside transporter in mouse lymphoblasts.
Topics: Adenosine; Animals; Binding Sites; Biological Transport; Blood Proteins; Cytidine; Drug Resistance; Inosine; Kinetics; Membrane Proteins; Mice; Mutation; Nucleoside Transport Proteins; Nucleotides; T-Lymphocytes; Thioinosine | 1985 |
Effects of nucleoside transport inhibitors on the salvage and toxicity of adenosine and deoxyadenosine in L1210 and P388 mouse leukemia cells.
Topics: Adenosine; Animals; Biological Transport; Coformycin; Deoxyadenosines; Dipyridamole; Inosine; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Pentostatin; Thioinosine | 1985 |
Nucleoside transport and metabolism in erythrocytes from the Yucatan miniature pig. Evidence that inosine functions as an in vivo energy substrate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Energy Metabolism; Erythrocytes; Inosine; Kinetics; Male; Nucleosides; Swine; Swine, Miniature | 1985 |
Purine metabolic enzymes in lymphocytes. IV. Effects of enzyme inhibitors and enzyme substrates on the blastogenic responses of human lymphocytes.
Topics: Adenosine; Adenosine Deaminase; Allopurinol; Coformycin; Enzyme Inhibitors; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Activation; Lymphocytes; Mitogens; Purine-Nucleoside Phosphorylase; Purines; Xanthine Oxidase | 1985 |
Evidence that the intracellular effects of adenosine in the guinea-pig aorta are mediated by inosine.
Topics: Adenosine; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Theophylline; Thioinosine | 1986 |
Accumulation and salvage of adenosine and inosine by isolated mature cardiac myocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Biological Transport, Active; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Methylthioinosine; Myocardium; Phosphorylation; Rats | 1985 |
Autoradiographic localization of adenosine uptake sites in rat brain using [3H]nitrobenzylthioinosine.
Topics: Adenosine; Animals; Autoradiography; Binding Sites; Inosine; Male; Rats; Rats, Inbred Strains; Thioinosine; Tissue Distribution; Tritium | 1985 |
Initiation factors eIF4A and C1 from wheat germ and the formation of mRNA X ribosome complexes.
Topics: Adenosine; Adenosine Triphosphate; Binding Sites; Eukaryotic Initiation Factor-4A; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Inosine; Peptide Initiation Factors; Reoviridae; Ribosomes; RNA, Messenger; RNA, Viral; Triticum | 1985 |
Adenosine uptake sites in rat brain: identification using [3H]nitrobenzylthioinosine and co-localization with adenosine deaminase.
Topics: Adenosine; Adenosine Deaminase; Animals; Autoradiography; Brain; Inosine; Male; Neurons; Nucleoside Deaminases; Rats; Rats, Inbred Strains; Thioinosine | 1985 |
Species differences in the binding of [3H]nitrobenzylthioinosine to the nucleoside transport system in mammalian central nervous system membranes: evidence for interconvertible conformations of the binding site/transporter complex.
Topics: Adenosine; Animals; Binding Sites; Biological Transport, Active; Brain; Cell Membrane; Diazepam; Dipyridamole; Dogs; Erythrocytes; Female; Guinea Pigs; Humans; Inosine; Male; Mice; Nucleosides; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Thioinosine | 1985 |
Changes in acid-base status, lactate concentration and purine metabolites during reconstructive aortic surgery.
Topics: Acid-Base Equilibrium; Adenosine; Aged; Aorta, Abdominal; Aortic Aneurysm; Arteriosclerosis; Humans; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Middle Aged; Purines; Xanthine; Xanthines | 1985 |
Evidence for adenosine triphosphate degradation in critically-ill patients.
Topics: Adenosine; Adenosine Triphosphate; Blood Pressure; Cardiac Output; Critical Care; Female; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Oxygen; Prognosis; Vasoconstrictor Agents; Xanthine; Xanthines | 1985 |
Urinary modified nucleosides as tumor markers in cancer of the urinary organs or female genital tract.
Topics: Adenosine; Adult; Carcinoma, Renal Cell; Female; Genital Neoplasms, Female; Guanosine; Humans; Inosine; Kidney Neoplasms; Nucleosides; Pseudouridine; Urinary Bladder Neoplasms; Urogenital Neoplasms | 1985 |
Role of adenosine uptake and metabolism by blood cells in the antiplatelet actions of dipyridamole, dilazep and nitrobenzylthioinosine.
Topics: Adenosine; Azepines; Blood Platelets; Dilazep; Dipyridamole; Erythrocytes; Humans; In Vitro Techniques; Inosine; Mopidamol; Platelet Aggregation; Thioinosine | 1985 |
Adenosine deaminase from Metridium senile (L.) a sea anemone.
Topics: Adenosine; Amino Acids; Aminohydrolases; Animals; Centrifugation; Chromatography, Gel; Cnidaria; Hydrogen-Ion Concentration; Inosine; Kinetics; Molecular Weight; Proteins; Spectrophotometry; Temperature; Time Factors | 1972 |
Effect of adenosine and some of its analogs on renal hemodyamics.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Inosine; Kidney; Kidney Transplantation; Male; Methane; Norepinephrine; Nucleosides; Phenoxybenzamine; Regional Blood Flow; Transplantation, Autologous; Vascular Resistance | 1973 |
Partial purification and properties of a nucleoside hydrolase from Crithidia.
Topics: Adenosine; Animals; Carbon Isotopes; Cations, Monovalent; Chromatography, Gel; Chromatography, Paper; Cytidine; Drug Stability; Edetic Acid; Eukaryota; Hot Temperature; Hydrogen-Ion Concentration; Inosine; Isoelectric Focusing; Kinetics; Magnesium; N-Glycosyl Hydrolases; Spectrophotometry, Ultraviolet; Temperature; Time Factors; Ultrafiltration; Uridine | 1973 |
Mechanism of inhibition of bacterial growth by adenine.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Bacterial Proteins; Carbon Radioisotopes; Culture Media; Depression, Chemical; DNA, Bacterial; Edetic Acid; Escherichia coli; Guanosine; Inosine; Orotic Acid; Oxygen Consumption; Phosphorus Radioisotopes; Purine Nucleotides; Pyrimidine Nucleotides; RNA, Bacterial; Uridine | 1974 |
Possible role of adenosine deaminase in suboptimal growth of the bacillus anthracis adenine auxotroph mutant.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Bacillus anthracis; Carbon Radioisotopes; Cell-Free System; Culture Media; Deoxyadenosines; Hypoxanthines; Inosine; Lyases; Mutation; Pentosyltransferases; Phosphates; Succinates; Virulence | 1973 |
Purine metabolism in Neisseria meningitidis. 2. Utilization of exogenous adenosine, guanosine and inosine.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Guanosine; Inosine; N-Glycosyl Hydrolases; Neisseria meningitidis; Purine-Nucleoside Phosphorylase | 1974 |
Changes in sarcoma 180 cells associated with drug-induced resistance to adenosine analogs.
Topics: Adenosine; Alkenes; Aminohydrolases; Animals; Carbon Isotopes; Cell Division; Cells, Cultured; Chromatography, Paper; Cross Reactions; Deamination; Drug Resistance; Floxuridine; Furans; Inosine; Methotrexate; Mice; Pentosyltransferases; Phosphotransferases; Purines; Ribonucleosides; Sarcoma 180; Time Factors | 1972 |
Presence of adenosine in the human term placenta. Determination of adenosine content and pathways of adenosine metabolism.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Aminohydrolases; Cesarean Section; Chromatography, Paper; Female; Humans; Hypoxanthines; Inosine; Ischemia; Labor, Obstetric; Nucleotidases; Pentosyltransferases; Phosphotransferases; Placenta; Pregnancy; Spectrophotometry, Ultraviolet; Time Factors; Xanthine Oxidase | 1972 |
Correlation of growth inhibition patterns to nucleoside transport models in Neurospora crassa.
Topics: Adenine; Adenosine; Guanosine; Inosine; Ligases; Models, Biological; Neurospora; Neurospora crassa; Nucleosides; Pyrimidines; Succinates; Time Factors; Uridine | 1973 |
Relationship between (8-14C)adenosine transport and growth inhibition in Neurospora crassa strain ad-8.
Topics: Adenosine; Carbon Radioisotopes; Deoxyribonucleosides; Deoxyuridine; Electron Transport; Guanosine; Inosine; Micropore Filters; Neurospora; Neurospora crassa; Nucleosides; Spores, Fungal; Thymidine; Uridine | 1974 |
Reaction of pseudouridine and inosine with N-cyclohexyl-N'-beta-(4-methylmorpholinium)ethylcarbodiimide.
Topics: Adenosine; Buffers; Chemical Phenomena; Chemistry; Cyclohexanes; Diphosphates; Drug Stability; Guanosine; Hydrogen-Ion Concentration; Hydrolysis; Imides; Inosine; Inosine Nucleotides; Morpholines; Nucleosides; Phosphates; Ribonucleases; Spectrophotometry; Stereoisomerism; Sulfonic Acids; Thymidine; Thymine; Time Factors; Toluene; Ultraviolet Rays; Uridine | 1971 |
Nucleoside transport by Novikoff rat hepatoma cells glowing in suspension culture. Specificity and mechanism of transport reactions and relationship to nucleoside incorporation into nucleic acids.
Topics: Adenosine; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chloromercuribenzoates; Chromatography, Paper; Chymotrypsin; Cytidine; Dipyridamole; Ethanol; Guanosine; Hot Temperature; Inosine; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Neuraminidase; Nucleic Acids; Nucleosides; Phospholipases; Phosphotransferases; Thymidine; Tritium; Trypsin; Uridine | 1971 |
Nucleotide pools in Novikoff rat hepatoma cells growing in suspension culture. 3. Effects of nucleosides in medium on levels of nucleotides in separate nucleotide pools for nuclear and cytoplasmic RNA synthesis.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cells, Cultured; Chromatography; Culture Media; Culture Techniques; Cytidine; Cytoplasm; Cytosine Nucleotides; Electrophoresis; Encephalomyocarditis virus; Guanosine; Inosine; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Phosphates; Phosphorus Isotopes; Rats; RNA; RNA, Viral; Time Factors; Tritium; Uridine | 1972 |
The regulation of purine utilization in bacteria. IV. Roles of membrane-localized and pericytoplasmic enzymes in the mechanism of purine nucleoside transport across isolated Escherichia coli membranes.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Biological Transport; Carbon Isotopes; Cell Membrane; Escherichia coli; Glucose; Guanine Nucleotides; Guanosine Triphosphate; Hypoxanthines; Inosine; Kinetics; Nucleosides; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Ribose; Temperature | 1972 |
Studies in prebiotic synthesis. VI. Synthesis of purine nucleosides.
Topics: Adenine; Adenosine; Chemical Phenomena; Chemistry; Chromatography, Paper; Diphosphates; Electrophoresis, Paper; Guanine; Guanosine; Hot Temperature; Hypoxanthines; Inosine; Kinetics; Magnesium; Nucleosides; Phosphates; Ribonucleosides; Ribose | 1972 |
Nucleoside-coated bacteriophage T4: a method for the detection and characterization of anti-nucleoside antibodies.
Topics: Adenosine; Animals; Antibodies; Antigen-Antibody Reactions; Coliphages; Complement System Proteins; Cross Reactions; Cytidine; DNA; Goats; Guanosine; Humans; Immune Sera; Inosine; Lupus Erythematosus, Systemic; Nucleosides; Periodic Acid; Rabbits; RNA, Transfer; Uridine | 1972 |
Inosine incorporation into myocardial nucleotides.
Topics: Adenine Nucleotides; Adenosine; Aminohydrolases; Animals; Carbon Isotopes; Guinea Pigs; Hypoxanthines; Inosine; Mathematics; Myocardium; N-Glycosyl Hydrolases; Nucleotidases; Perfusion; Phosphoric Monoester Hydrolases; Spectrophotometry, Ultraviolet | 1972 |
Liquid chromatographic analysis of nucleosides, purine base-modified adenosine derivatives and 3',5'-cyclic AMP.
Topics: Adenosine; Chromatography, Ion Exchange; Cyclic AMP; Cytidine; Guanosine; Inosine; Methods; Microchemistry; Purines; Ribonucleosides; Uridine | 1973 |
Actions of various cyclic nucleotides, nucleosides and purine bases on the synthesis of corticosterone in vitro.
Topics: Adenine; Adenosine; Adrenal Glands; Adrenocorticotropic Hormone; Allopurinol; Animals; Corticosterone; Cyclic AMP; Cyclic GMP; Drug Synergism; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Nucleotides; Male; Nucleosides; Nucleotides; Purines; Rats; Uracil Nucleotides; Xanthines | 1972 |
Specificity of adenosine on transmitter output at the neuromuscular junction.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Calcium; Cyclic AMP; Cystine; Diaphragm; Evoked Potentials; Guanosine; In Vitro Techniques; Inosine; Magnesium; Membrane Potentials; Muscle Contraction; Neuromuscular Junction; Rats; Uridine | 1973 |
Studies on the antilipolytic effect of adenosine and related compounds in isolated fat cells.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Culture Techniques; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Glycerol; Hypoxanthines; Inosine; Insulin; Male; Norepinephrine; Rats; Theophylline; Xanthines | 1973 |
Subcellular localization of (14C)adenine derivatives newly-formed in cerebral tissues and the effects of electrical excitation.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Brain; Carbon Radioisotopes; Cell Nucleus; Centrifugation, Density Gradient; Cyclic AMP; Cytosol; Electric Stimulation; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Microsomes; Mitochondria; Synaptic Transmission; Synaptosomes; Tritium | 1973 |
Myocardial nucleotide synthesis from purine bases and nucleosides. Comparison of the rates of formation of purine nucleotides from various precursors and identification of the enzymatic routes for nucleotide formation in the isolated rat heart.
Topics: Adenine; Adenosine; Animals; Carbon Radioisotopes; Enzyme Precursors; Hypoxanthines; In Vitro Techniques; Inosine; Methods; Myocardium; Oxidative Phosphorylation; Phosphotransferases; Purine Nucleotides; Rats; Tritium | 1973 |
The effects of bases and nucleosides on the intracellular contents of nucleotides and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.
Topics: Adenine; Adenine Nucleotides; Adenosine; Carbon Radioisotopes; Cytosine Nucleotides; Escherichia coli; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthines; Inosine; Inosine Nucleotides; Kinetics; Organophosphorus Compounds; Orotic Acid; Pentosephosphates; Phosphoric Acids; Ribonucleosides; Ribonucleotides; Time Factors; Uracil; Uracil Nucleotides; Uridine | 1974 |
Metabolism and transport of purine nucleosides by membrane preparations of Micrococcus sodonensis.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aminohydrolases; Biological Transport, Active; Carbon Radioisotopes; Hydrogen-Ion Concentration; Inosine; Magnesium; Membranes; Micrococcus; Microscopy, Electron; Organophosphorus Compounds; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Spheroplasts | 1974 |
Output of (14C)adenine nucleotides and their derivatives from cerebral tissues. Tetrodotoxin-resistant and calcium ion-requiring components.
Topics: Adenine Nucleotides; Adenosine; Animals; Bicarbonates; Brain; Calcium; Carbon Radioisotopes; Electric Stimulation; Glucose; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Lactates; Phosphotransferases; Tetrodotoxin | 1973 |
Studies on the coronary dilator actions of some adenosine analogues.
Topics: Adenosine; Aminohydrolases; Animals; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Depression, Chemical; Dogs; Drug Synergism; Female; Heart; Heart Rate; Inosine; Male; Phosphotransferases; Stimulation, Chemical; Structure-Activity Relationship | 1974 |
Uptake and relase of (14C)adenine derivatives at beds of mammalian cortical synaptosomes in a superfusion system.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Biological Transport; Carbon Radioisotopes; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Hypoxanthines; Inosine; Lactates; Mitochondria; Nylons; Potassium Chloride; Spectrometry, Fluorescence; Synaptosomes; Tetrodotoxin; Time Factors | 1974 |
Effect of pharmacological agents on human keratinocyte mitosis in vitro. I. Inhibition by adenine nucleotides.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cytidine; Cytosine Nucleotides; Depression, Chemical; Guanine; Guanine Nucleotides; Guanosine; Guanosine Triphosphate; Humans; Hypoxanthines; Inosine; Inosine Nucleotides; Mitosis; Skin; Thymine Nucleotides; Uracil Nucleotides | 1974 |
Purine nucleotide metabolism in the cat brain after one hour of complete ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Carbon Radioisotopes; Cats; Cerebrovascular Circulation; Chromatography, Ion Exchange; Formates; Guanine Nucleotides; Guanosine Triphosphate; Hypoxanthines; Inosine; Inosine Nucleotides; Ischemia; NAD; Pentosyltransferases; Phosphotransferases; Purine Nucleotides; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1974 |
The role of direct phosphorylation in the mechanism of adenosine utilization for nucleotide synthesis in mouse erythrocytes.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Radioisotopes; Chromatography, Paper; Erythrocytes; Hypoxanthines; Inosine; Kidney; Kinetics; Liver; Male; Mathematics; Mice; Myocardium; Organ Specificity; Phosphotransferases; Time Factors | 1974 |
Theophylline inhibition of nucleoside transport and its relation to cyclic AMP in skeletal muscle.
Topics: Adenine; Adenosine; Animals; Biological Transport; Bucladesine; Caffeine; Carbon Radioisotopes; Chromatography, Paper; Cyclic AMP; Hypoxanthines; In Vitro Techniques; Inosine; Isoproterenol; Muscle Contraction; Muscles; Nucleosides; Phenytoin; Propranolol; Protein Binding; Purines; Rana pipiens; Ribose; Sorbitol; Theophylline; Tritium; Uridine | 1974 |
Output of ( 14 C)adenine derivatives on electrical excitation of tissues from the brain: calcium ion-sensitivity and an accompanying re-uptake process.
Topics: Adenine; Adenine Nucleotides; Adenosine; Brain; Calcium; Carbon Isotopes; Cyclic AMP; Electric Stimulation; Hypoxanthines; In Vitro Techniques; Inosine; Neurotransmitter Agents | 1972 |
A unique example of virtual proton-proton coupling in purine nucleosides.
Topics: Adenosine; Benzyl Compounds; Energy Transfer; Inosine; Molecular Conformation; Nucleosides; Protons; Spectrum Analysis | 1974 |
The binding sites of nucleosides or nucleotides to diethylenetriaminecobalt(III).
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Circular Dichroism; Cobalt; Deoxyribonucleotides; Ethylenes; Hydrogen-Ion Concentration; Inosine; Molecular Conformation; Organometallic Compounds; Polyamines; Ribonucleosides; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Uridine | 1974 |
Dinucleotide sequences containing both base and sugar modifications in the ribosomal RNA of Crithidia fasciculata.
Topics: Adenosine; Animals; Base Sequence; Chromatography, DEAE-Cellulose; Chromatography, Paper; Drug Stability; Eukaryota; Hydrogen-Ion Concentration; Inosine; Ribonucleotides; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Uridine | 1974 |
Biochemical and genetic studies of laboratory purine auxotrophic strains of Micrococcus luteus.
Topics: Adenine; Adenosine; Carbon Dioxide; Crosses, Genetic; Hypoxanthines; Imidazoles; Inosine; Micrococcus; Mutation; Purines; Recombination, Genetic; Ribonucleotides; Transformation, Genetic | 1974 |
Letter: The tautomeric form of inosine in aqueous solution.
Topics: Adenosine; Binding Sites; Guanosine; Hydrogen-Ion Concentration; Inosine; Molecular Conformation; Osmolar Concentration; Structure-Activity Relationship; Water | 1974 |
The inhibition of platelet aggregation by an aorta intima extract.
Topics: Achilles Tendon; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Aorta; Collagen; Endothelium; Epinephrine; Humans; Hypoxanthines; Inosine; Muscle, Smooth; Platelet Adhesiveness; Thrombin; Tissue Extracts | 1974 |
[The effect of methylxanthines on catecholamine and adenylate nucleotide concentration in rat myocardium].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Caffeine; Inosine; Inosine Nucleotides; Myocardium; Phosphorus; Rats; Stimulation, Chemical; Strophanthins; Theobromine; Theophylline; Tyramine; Xanthines | 1974 |
The interaction of concanavalin A with sheep erythrocytes.
Topics: Adenosine; Animals; Binding Sites; Buffers; Cattle; Concanavalin A; Dogs; Erythrocytes; Glucose; Hemagglutination; Humans; Inosine; Iodine Radioisotopes; Potassium; Protein Binding; Rabbits; Serum Albumin, Bovine; Sheep; Temperature; Time Factors; Trypsin | 1974 |
Inhibition of adenosine uptake by platelets.
Topics: Adenine; Adenosine; Blood Platelets; Buffers; Carbon Isotopes; Dipyridamole; Drug Synergism; Humans; Hypoxanthines; In Vitro Techniques; Inosine; Uric Acid | 1972 |
Adenosine inhibition of human platelet aggregation by ADP.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Buffers; Cell Aggregation; Drug Synergism; Humans; Hypoxanthines; Inosine; Time Factors | 1972 |
Adenosine deaminase inhibition by N 6 -(2 -isopentenyl) adenosine.
Topics: Adenosine; Aminohydrolases; Animals; Hot Temperature; In Vitro Techniques; Inosine; Kinetics; Liver; Male; Nucleosides | 1972 |
Guanine and hypoxanthine formation in iridophores of the bullfrog tadpole.
Topics: Adenosine; Animals; Anura; Autoradiography; Carbon Isotopes; Chromatography, Gel; Chromatophores; Deoxyribonucleosides; Guanine; Guanosine; Hypoxanthines; Inosine; Kinetics; Larva; Nucleosides; Pentosyltransferases; Phosphates; Rana catesbeiana; Skin; Spectrophotometry; Tritium; Ultraviolet Rays | 1972 |
Phosphorylation of adenosine and deoxyadenosine in Ehrlich ascites carcinoma cells resistant to 6-(Methylmercapto)purine ribonucleoside.
Topics: Adenosine; Aminohydrolases; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Chromatography, Thin Layer; Deoxyadenosines; Drug Resistance; Guanosine; Hypoxanthines; Inosine; Kinetics; Mice; Nucleosides; Phosphotransferases; Ribonucleosides; Sulfides | 1972 |
The biosynthesis of DNA by insects. IV. Metabolism of purine deoxyribonucleosides during adult development of the Cecropia silkmoth.
Topics: Adenosine; Adenosine Monophosphate; Aminohydrolases; Bombyx; Carbon Isotopes; Chromatography, Paper; Deoxyadenosines; DNA; Guanine Nucleotides; Guanosine; Humans; Inosine; Kinetics; Nucleosides | 1972 |
Stereoselective differentiation between ribonucleosides and deoxynucleosides by reaction with the copper(II) acetate dimer.
Topics: Acetates; Adenosine; Copper; Cytidine; Deoxyadenosines; Deoxyribonucleosides; Deoxyuridine; Guanosine; Inosine; Magnetic Resonance Spectroscopy; Protein Binding; Ribonucleosides; Spectrum Analysis; Thymidine | 1972 |
Incorporation of nucleosides into the nucleotide pools of human erythrocytes. Adenosine and its analogs.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Antibiotics, Antineoplastic; Aza Compounds; Carbohydrate Metabolism; Deoxyadenosines; Erythrocytes; Fluorine; Humans; Inosine; Mercaptopurine; Nucleosides; Phosphotransferases; Pyrazoles; Pyrimidines; Pyrimidinones; Pyrroles; Ribonucleosides; Structure-Activity Relationship | 1973 |
Lennard-Jones potential calculations of the barrier to rotation around the glycosidic C-N linkage in selected purine nucleosides and nucleotides. A direct comparison of the results of 6-12 potential calculations with results of semiempirical molecular orb
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Deoxyadenosines; Glycosides; Guanosine; Inosine; Nucleic Acid Conformation; Potentiometry; Purine Nucleosides; Purine Nucleotides; Quantum Theory; X-Ray Diffraction | 1973 |
A model for nucleotide regulation of aspartate transcarbamylase.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Allosteric Regulation; Aspartic Acid; Binding Sites; Carbamates; Cytidine; Cytosine; Cytosine Nucleotides; Enzyme Activation; Escherichia coli; Guanosine Triphosphate; Inosine; Inosine Nucleotides; Kinetics; Mathematics; Models, Chemical; Nucleotides; Phosphoric Acids; Protein Conformation; Radioisotopes; Transferases | 1972 |
Purification and properties of purine nucleoside phosphorylase from Salmonella typhimurium.
Topics: Adenosine; Ammonium Sulfate; Calcium Phosphates; Cations, Divalent; Chromatography, DEAE-Cellulose; Chromatography, Gel; Deoxyadenosines; Deoxyribonucleosides; Electrophoresis, Disc; Guanosine; Hydrogen-Ion Concentration; Inosine; Kinetics; Macromolecular Substances; Molecular Weight; Pentosyltransferases; Phosphates; Protamines; Ribonucleosides; Salmonella typhimurium; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Sulfuric Acids; Ultracentrifugation | 1973 |
Pairing of inosine with adenosine in codon position two in the translation of polyinosinic acid.
Topics: Adenosine; Amino Acids; Bacterial Proteins; Carbon Isotopes; Escherichia coli; Glycine; Inosine; Inosine Nucleotides; Magnesium; Models, Chemical; Nucleic Acid Conformation; Peptide Biosynthesis; Polynucleotides; Protein Biosynthesis; RNA, Messenger; Spectrophotometry, Ultraviolet; Spermine; Streptomycin; Valine | 1973 |
Purine nucleoside metabolism in Escherichia coli.
Topics: Adenosine; Aminohydrolases; Biological Transport; Carbon Radioisotopes; Chromatography, Gel; Enzyme Induction; Escherichia coli; Guanine; Guanosine; Hypoxanthines; Inosine; Kinetics; Mutation; Pentosyltransferases; Phosphotransferases; Purine Nucleosides; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Xanthines | 1973 |
Effect of AMP and related compounds on glycogen content of Tetrahymena.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anaerobiosis; Animals; Carbon Dioxide; Carbon Isotopes; Cell Count; Culture Media; Cytidine; Glycogen; Glyoxylates; Inosine; Lipid Metabolism; Tetrahymena pyriformis; Uridine | 1972 |
Oxidative activation of Bacillus cereus spores.
Topics: Adenosine; Alanine; Bacillus cereus; Boric Acids; Food Microbiology; Hot Temperature; Inosine; Kinetics; Mercaptoethanol; Spores; Spores, Bacterial; Stereoisomerism; Stimulation, Chemical; Time Factors | 1973 |
Phosphorylation and deamination of adenosine by the isolated, perfused rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Animals; Carbon Isotopes; Chromatography, Gel; Chromatography, Thin Layer; Hypoxanthines; Inosine; Male; Models, Biological; Myocardium; Perfusion; Phosphotransferases; Rats; Time Factors | 1972 |
Interference with nucleoside transport in mouse lymphoma cells proliferating in culture.
Topics: Adenosine; Animals; Ascitic Fluid; Aza Compounds; Biological Transport; Bromodeoxyuridine; Carbon Isotopes; Cell Division; Cell-Free System; Cells, Cultured; Guanosine; Inosine; Lymphoma; Male; Mercaptopurine; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pyrazoles; Pyrimidinones; Pyrroles; Ribonucleosides; Thymidine; Time Factors; Transplantation, Homologous | 1972 |
[Reproduction and energy metabolism of in-vitro cultivatable Ehrlich-ascites tumor cells in glucose free medium].
Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Culture Media; Cytidine; Glucose; Guanosine; In Vitro Techniques; Inosine; Phosphorylases; Ribose; Uridine | 1972 |
[The effect of the coronary dilator lidoflazine on myocardial adenosine metabolism in ischemia and anoxia].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Membrane Permeability; Coronary Vessels; Dogs; Heart; Hypoxanthines; Hypoxia; Inosine; Ischemia; Lactates; Myocardium; Phosphocreatine; Piperazines; Vasodilator Agents | 1972 |
Studies in prebiotic synthesis: VII. Solid-state synthesis of purine nucleosides.
Topics: Adenosine; Deoxyribose; Guanosine; Hypoxanthines; Inosine; Purine Nucleosides; Seawater | 1972 |
The action of ATP in the guinea-pig heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carbon Isotopes; Guinea Pigs; Heart; In Vitro Techniques; Inosine; Kinetics; Myocardium; Phosphorus Isotopes | 1973 |
Pathways of nucleotide metabolism in Schistosoma mansoni. II. Disposition of adenosine by whole worms.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aminohydrolases; Animals; Carbon Isotopes; Culture Media; Erythrocytes; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Inosine Nucleotides; Mice; Nucleosides; Pentosyltransferases; Purines; Ribose; Schistosoma mansoni; Time Factors | 1973 |
Effect of persantin on nucleoside metabolism of the perfused rabbit heart.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Isotopes; Dipyridamole; Heart; In Vitro Techniques; Inosine; Myocardium; Nucleosides; Perfusion; Rabbits | 1973 |
Release of ( 14 C)adenine derivatives from isolated subsystems of the guinea pig brain: actions of electrical stimulation and of papaverine.
Topics: Adenine Nucleotides; Adenosine; Animals; Brain; Brain Chemistry; Carbon Isotopes; Chromatography, Thin Layer; Electric Stimulation; Guinea Pigs; Inosine; Limbic System; Olfactory Bulb; Papaverine; Superior Colliculi | 1973 |
Determination of acid-soluble nucleosides and bases in myocardium by thin-layer methods.
Topics: Adenosine; Animals; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dogs; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Methods; Myocardium; Solubility | 1973 |
The role of fructose in restoration of organic phosphate compounds in outdated bank blood.
Topics: Adenosine; Adenosine Triphosphate; Blood Preservation; Citrates; Diphosphoglyceric Acids; Erythrocytes; Fructose; Glucose; Glyceric Acids; Humans; Hydrogen-Ion Concentration; Inosine; Organophosphorus Compounds; Oxygen; Phosphates; Pyruvates | 1973 |
Introduction of a 2',3' double bond into purine ribonucleosides by selective elimination reactions.
Topics: Adenosine; Benzyl Compounds; Chemical Phenomena; Chemistry; Inosine; Methods; Purines; Ribonucleosides; Stereoisomerism; Structure-Activity Relationship; Tosyl Compounds | 1973 |
Reevaluation of the role of ATP in autolysis of liver protein.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Colorimetry; Hydrolysis; Hypoxanthines; In Vitro Techniques; Indicators and Reagents; Inosine; Liver; Male; Proteins; Rats | 1973 |
Purine-nucleoside: orthophosphate ribosyltransferase activity in the hepatopancreas of Helix pomatia (Gastropoda).
Topics: Adenosine; Animals; Calcium; Chromatography, Gel; Chromatography, Paper; Digestive System; Drug Stability; Guanosine; Hibernation; Hydrogen-Ion Concentration; Inosine; Kinetics; Liver; Magnesium; Pancreas; Pentosyltransferases; Phosphates; Ribonucleosides; Snails; Spectrophotometry, Ultraviolet; Temperature; Time Factors; Uridine; Xanthines | 1973 |
Adenosine formation and metabolism during adenosine triphosphate catabolism in Ehrlich ascites tumor cells.
Topics: Adenosine; Adenosine Triphosphate; Aminohydrolases; Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Deamination; Glucose; In Vitro Techniques; Inosine; Mice; Mice, Inbred ICR; Phosphotransferases | 1973 |
Studies on (8-14C)adenosine-5'-carboxylic acid ethyl ester. I. Metabolic fate in the dog, rat and mouse.
Topics: Adenosine; Administration, Oral; Animals; Carbon Radioisotopes; Carboxylic Acids; Chromatography, Ion Exchange; Dogs; Female; Half-Life; Inosine; Male; Mass Spectrometry; Mice; Organ Specificity; Rats; Species Specificity; Time Factors; Vasodilator Agents | 1973 |
Adenosine-induced bacteriostasis in Micrococcus sodonensis.
Topics: Adenosine; Carbon Radioisotopes; Chromatography, Paper; Culture Media; Hypoxanthines; Inosine; Micrococcus; Spectrophotometry; Thiamine; Time Factors | 1973 |
Myocardial: blood purine nucleoside concentration ratios in canine myocardium.
Topics: Adenosine; Animals; Coronary Disease; Coronary Vessels; Dogs; Hypoxanthines; Inosine; Ligation; Myocardium; Oxygen; Pericardial Effusion; Purine Nucleosides; Spectrophotometry | 1973 |
Adenosine metabolism in platelets and plasma.
Topics: Adenosine; Adenosine Diphosphate; Animals; Anticoagulants; Binding Sites; Blood Cell Count; Blood Platelets; Buffers; Carbon Radioisotopes; Centrifugation, Density Gradient; Depression, Chemical; Dipyridamole; Guinea Pigs; Humans; Hypoxanthines; Inosine; Lithium; Platelet Adhesiveness; Prostaglandins; Rabbits; Rats; Receptors, Drug; Species Specificity; Temperature; Time Factors; Uric Acid | 1973 |
The interaction of myosin, actin and ATP in the intact muscle.
Topics: Actins; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Anura; Binding Sites; Carbon Radioisotopes; Ethylmaleimide; Inosine; Inosine Nucleotides; Iodoacetates; Kinetics; Macromolecular Substances; Models, Biological; Muscle Contraction; Muscles; Myosins; Peptides; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
Incorporation of purine analogs into the nucleotide pools of human erythrocytes.
Topics: Adenosine; Chromatography, Ion Exchange; Erythrocytes; Guanine Nucleotides; Guanosine; Hydrogen-Ion Concentration; Inosine; Inosine Nucleotides; Kinetics; Pentosephosphates; Pentosyltransferases; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
A role of liver adenosine in the renewal of the adenine nucleotides of human and rabbit erythrocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Erythrocytes; Humans; Hypoxanthines; Inosine; Kinetics; Liver; Models, Biological; Perfusion; Rabbits; Species Specificity; Time Factors; Tritium; Xanthines | 1973 |
Adenosine and inosine 5'-triphosphates. Protonation, metal-ion coordination, and charge-transfer interaction between two ligands within ternary complexes.
Topics: Adenosine; Adenosine Triphosphate; Binding Sites; Copper; Hydrogen-Ion Concentration; Inosine; Inosine Nucleotides; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Structural; Molecular Conformation; Pyridines; Spectrophotometry, Ultraviolet | 1974 |
Release of adenosine from human hearts during angina induced by rapid atrial pacing.
Topics: Adenosine; Adult; Aged; Angina Pectoris; Animals; Arteriosclerosis; Coronary Disease; Creatine; Creatine Kinase; Dogs; Female; Humans; Hypoxanthines; Inosine; L-Lactate Dehydrogenase; Lactates; Male; Middle Aged; Myocardium; Physical Exertion; Potassium; Sodium | 1974 |
The separation of certain bases, nucleosides, and nucleotides related to adenine by continuous-flow electrophoresis.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Electrophoresis; Guanine Nucleotides; Inosine; Methods; Nucleosides; Nucleotides | 1974 |
Adenosine aminohydrolase inhibition in cosolvent--buffer mixtures.
Topics: Adenosine; Alkenes; Aminohydrolases; Binding Sites; Binding, Competitive; Buffers; Dioxins; Hydrogen-Ion Concentration; Inosine; Intestinal Mucosa; Kinetics; Mathematics; Protein Binding; Spectrophotometry, Ultraviolet | 1974 |
The effect of inosine on blood pressure in the rat.
Topics: Adenosine; Anesthesia; Animals; Atropine; Blood Pressure; Dose-Response Relationship, Drug; Female; Inosine; Pentobarbital; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Vasomotor System | 1974 |
Inhibition of protein synthesis by 5'-sulfamoyladenosine.
Topics: Adenine Nucleotides; Adenosine; Aminohydrolases; Animals; Bacterial Proteins; Carbon Isotopes; Cells, Cultured; Deoxyadenosines; DNA, Bacterial; Escherichia coli; Inosine; Intestinal Mucosa; Leukemia L1210; Lysine; Mice; Muscles; Nucleosides; Phenylalanine; Proline; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; Streptococcus; Structure-Activity Relationship; Sulfonamides | 1971 |
Adenosine-5'-monophosphate aminohydrolase of human placenta.
Topics: Adenosine; Adenosine Monophosphate; Albumins; Aminohydrolases; Ammonia; Blood Coagulation; Chromatography, Paper; Cytoplasm; Deamination; Dialysis; Edetic Acid; Female; Fluorides; Globulins; Humans; Inosine; Inosine Nucleotides; N-Glycosyl Hydrolases; Phosphates; Placenta; Pregnancy; Time Factors | 1971 |
Quantitative studies of the release of purine compounds following stimulation of non-adrenergic inhibitory nerves in the stomach.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Bufo marinus; Chromatography, Paper; Electric Stimulation; Gastric Mucosa; In Vitro Techniques; Inosine; Kinetics; Neurons; Nucleosides; Nucleotides; Perfusion; Purines; Spectrophotometry; Stimulation, Chemical; Stomach; Time Factors; Ultraviolet Rays; Vagus Nerve | 1971 |
Membrane transport of nucleosides in rabbit polymorphonuclear leukocytes.
Topics: Adenine Nucleotides; Adenosine; Animals; Biological Transport; Borates; Carbon Isotopes; Carrier Proteins; Cell Membrane; Chromatography, Ion Exchange; Chromatography, Paper; Deamination; Female; Inosine; Kinetics; Leukocytes; Male; Mathematics; Models, Structural; Neutrophils; Nucleosides; Protein Conformation; Rabbits; Structure-Activity Relationship; Thymidine; Tritium | 1972 |
Studies on the reversal of the selective antitumour effect of the aziridinyl derivative CB 1954 by 4-amino-5-imidazolecarboxamide.
Topics: Adenosine; Amides; Amines; Animals; Azirines; Benzoates; Carcinoma 256, Walker; Chromatography, Thin Layer; Cysteine; Guanosine; Imidazoles; Inosine; Leucine; Male; Nitro Compounds; ortho-Aminobenzoates; Purines; Pyrimidines; Rats; Thymidine; Time Factors; Tritium; Uridine | 1972 |
Metabolic significance of adenosine in the mouse erythrocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Alkaline Phosphatase; Aminohydrolases; Animals; Carbon Isotopes; Chromatography; Erythrocytes; Hypoxanthines; In Vitro Techniques; Inosine; Intestine, Small; Kidney; Liver; Male; Mice; Myocardium; Nucleotides; Purines; Ribose; RNA | 1972 |
Nucleoside phosphorylase: localization and role in the myocardial distribution of purines.
Topics: Adenosine; Aminohydrolases; Animals; Cell Nucleus; Cytoplasm; Epithelial Cells; Epithelium; Guinea Pigs; Heart; Histocytochemistry; Hypoxanthines; Inosine; Muscle, Smooth; Myocardium; N-Glycosyl Hydrolases; Perfusion; Ribose | 1972 |
Adaptive significance of inosine and adenosine kinase activities in cultured human skin fibroblasts.
Topics: Adenine; Adenosine; Azaserine; Cells, Cultured; Fibroblasts; Guanine; Humans; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Phosphotransferases; Skin; Thymidine; Tritium | 1972 |
Metabolism of nucleosides by isolated mouse liver mitochondria.
Topics: Adenosine; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Cytidine; Electrophoresis, Paper; Guanosine; Inosine; Male; Mice; Mice, Inbred Strains; Mitochondria, Liver; Nucleosides; Nucleotides; Thymidine; Tritium; Uridine | 1972 |
Uptake and metabolism of adenosine by human erythrocyte ghosts.
Topics: Adenine Nucleotides; Adenosine; Adult; Aminohydrolases; Carbon Isotopes; Cell Membrane; Diffusion; Dipyridamole; Erythrocytes; Humans; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Phosphotransferases | 1972 |
Incorporation and turnover of adenosine-U- 14 C in perfused guinea pig myocardium.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Isotopes; Guinea Pigs; Hypoxanthines; Inosine; Models, Biological; Myocardium | 1972 |
Kinetics of adenosine uptake by erythrocytes, and the influence of dipyridamole.
Topics: Adenosine; Animals; Carbon Isotopes; Depression, Chemical; Diffusion; Dipyridamole; Erythrocytes; Guinea Pigs; Inosine; Kinetics; Mathematics; Methylation; Models, Biological; Octanols; Osmolar Concentration | 1972 |
Fate of adenosine in the ischemic and anoxic myocardium during anaerobic perfusion.
Topics: Adenosine; Anaerobiosis; Animals; Carbon Isotopes; Extracellular Space; Hypoxanthines; Hypoxia; Inosine; Inulin; Ischemia; Myocardium; Perfusion; Rats | 1972 |
Kinetics and the mechanism of action of adenosine aminohydrolase.
Topics: Adenosine; Alcohols; Aminohydrolases; Ammonia; Animals; Binding Sites; Catalysis; Cattle; Chloromercuribenzoates; Colorimetry; Deuterium; Duodenum; Hydrogen-Ion Concentration; Inosine; Isoflurophate; Isomerism; Kinetics; Mathematics; Methanol; Models, Chemical; Ribonucleosides; Spectrophotometry; Structure-Activity Relationship; Ultraviolet Rays | 1972 |
Metabolism of ( 14 C)adenine and derivatives by cerebral tissues, superfused and electrically stimulated.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Electric Stimulation; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Lactates | 1972 |
Purine uptake and utilization by the avian malaria parasite Plasmodium lophurae.
Topics: Adenosine; Animals; Carbon Isotopes; Chromatography; DNA; Ducks; Erythrocytes; Hydrolysis; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Malaria, Avian; Mathematics; Plasmodium; Purines; RNA; Tritium | 1972 |
A species difference in the uptake of adenosine by heart.
Topics: Adenosine; Animals; Carbon Isotopes; Depression, Chemical; Dipyridamole; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Myocardium; Perfusion; Phosphates; Phosphotransferases; Rats; Species Specificity | 1971 |
Helical complexes of polyriboinosinic acid with copolymers of polyribocytidylic acid containing inosine, adenosine and uridine residues.
Topics: Adenosine; Cytosine Nucleotides; Inosine; Inosine Nucleotides; Molecular Biology; Nucleic Acid Denaturation; Polynucleotides; Spectrum Analysis; Ultracentrifugation; Ultraviolet Rays; Uridine | 1971 |
The reaction of glyoxal with nucleic acid components. 3. Kinetics of the reaction with monomers.
Topics: Adenosine; Aldehydes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytidine; Drug Stability; Formaldehyde; Guanosine; Hydrogen-Ion Concentration; Inosine; Kinetics; Mathematics; Nucleosides; Osmolar Concentration; Spectrophotometry; Ultraviolet Rays; Uridine | 1971 |
The mechanism of aristeromycin. I. Growth inhibition of Xanthomonas oryzae by aristeromycin.
Topics: Adenine; Adenosine; Anti-Bacterial Agents; Cytidine; Cytosine; Deoxyuridine; Guanine; Guanosine; Hypoxanthines; Inosine; Nucleosides; Thymidine; Thymine; Uracil; Uridine; Xanthines; Xanthomonas | 1971 |
The enzymatic microestimation of inosine, adenosine and inosinic acid.
Topics: Adenosine; Aminohydrolases; Animals; Cats; Clinical Enzyme Tests; Glutamate Dehydrogenase; Inosine; Methods; Microchemistry; Myocardium; Nucleosides; Pentosyltransferases; Xanthine Oxidase | 1971 |
Control of adenylate kinase by prostaglandins E2 and E3.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Autoradiography; Blood Platelets; Brain; Carbon Isotopes; Carbon Radioisotopes; Chromatography, Thin Layer; Enzyme Activation; Humans; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Models, Biological; Muscles; Phosphoric Monoester Hydrolases; Phosphotransferases; Plants; Prostaglandins; Protein Binding; Rats | 1971 |
Pathways of purine ribonucleotide catabolism in Ehrlich ascites tumor cells in vitro.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthines; Inosine; Inosine Nucleotides; Kinetics; Models, Biological; Nucleotides; Ribonucleosides; Ribonucleotides; Xanthines | 1971 |
[Relaxant effect of adenosine triphosphate and its related nucleotides on the guinea-pig taenia coli].
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine; Colon; Depression, Chemical; Electric Stimulation; Guanine; Guanosine; Guinea Pigs; Imidazoles; In Vitro Techniques; Inosine; Muscle, Smooth; Nucleotides; Phenoxybenzamine; Phentolamine; Quinidine | 1971 |
Nanosecond relaxation processes in aqueous mononucleoside solutions.
Topics: Adenosine; Chemical Phenomena; Chemistry, Physical; Deoxyadenosines; Guanosine; Inosine; Mathematics; Microchemistry; Nucleosides; Pressure; Purines; Pyrazoles; Pyrimidines; Ribose; Temperature; Urea; Vibration; Water | 1971 |
Influence of dipyridamol (Persantin) on myocardial adenosine metabolism.
Topics: Adenine Nucleotides; Adenosine; Animals; Biological Transport; Cell Membrane Permeability; Coronary Circulation; Culture Techniques; Deamination; Depression, Chemical; Diffusion; Dipyridamole; Dogs; Erythrocytes; Heart; Homeostasis; Inosine; Ischemia; Myocardium | 1970 |
The proposed 5'-nucleotidase inhibitor in human leukemic cells is an artefact.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Humans; Inosine; Leukemia; Nucleotidases | 1984 |
Accumulation and inactivation of adenosine by fat cells from hypothyroid rats.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Age Factors; Animals; Hypothyroidism; Inosine; Lipolysis; Male; Norepinephrine; Phosphorylation; Propylthiouracil; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1984 |
Purine receptors in trachea: studies with adenosine deaminase and dipyridamole.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Airway Resistance; Animals; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Inosine; Male; Muscle, Smooth; Nucleoside Deaminases; Receptors, Neurotransmitter; Receptors, Purinergic; Trachea | 1984 |
Heterogeneous distribution of adenosine transport sites labelled by [3H]nitrobenzylthioinosine in rat brain: an autoradiographic and membrane binding study.
Topics: Adenosine; Animals; Autoradiography; Brain; Brain Chemistry; Cell Membrane Permeability; Inosine; Male; Membranes; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Thioinosine | 1984 |
Benzodiazepine inhibition of site-specific binding of nitrobenzylthioinosine, an inhibitor of adenosine transport.
Topics: Adenosine; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Biological Transport; Brain; Erythrocytes; Humans; In Vitro Techniques; Inosine; Membranes; Thioinosine | 1981 |
Release of nucleosides and nucleotides from the rabbit heart by sympathetic nerve stimulation.
Topics: Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Adrenergic beta-Antagonists; Animals; Dilazep; Dipyridamole; Electric Stimulation; Heart; Hypoxanthines; Inosine; Myocardium; Norepinephrine; Nucleosides; Nucleotides; Phentolamine; Propranolol; Rabbits; Sympathetic Nervous System | 1982 |
Nitrobenzylthioinosine inhibition of adenosine uptake in guinea-pig brain.
Topics: Adenosine; Animals; Brain; Guinea Pigs; In Vitro Techniques; Inosine; Synaptosomes; Temperature; Thioinosine | 1983 |
Effect of beta-adrenergic blockade on nucleoside release from the hypoperfused isolated heart.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Atenolol; Coronary Circulation; Guinea Pigs; Heart; Inosine; Male; Myocardium; Norepinephrine; Nucleosides; Oxygen Consumption; Perfusion; Propranolol; Regional Blood Flow; Time Factors | 1984 |
Inhibition by purine compounds of cyclic GMP-stimulated cyclic AMP phosphodiesterase activity from a particulate fraction of rat striatum.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Hypoxanthines; Inosine; Male; Purines; Rats; Theophylline | 1980 |
[Purine metabolism of the human erythrocyte].
Topics: Adenosine; Erythrocyte Membrane; Erythrocytes; Humans; Inosine; Kinetics; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Phosphorylation; Phosphotransferases; Purine Nucleosides; Purine Nucleotides; Purines; Ribose-Phosphate Pyrophosphokinase | 1983 |
Adenosine-resistant Chinese hamster fibroblast variants with hyperactive adenosine-deaminase: an analysis of the protection against exogenous adenosine afforded by increased activity of the deamination pathway.
Topics: Adenosine; Adenosine Deaminase; Animals; Cell Line; Coformycin; Cricetinae; Cricetulus; Drug Resistance; Fibroblasts; Hypoxanthine; Hypoxanthines; Inosine; Models, Chemical; Nucleoside Deaminases; Phosphoribosyl Pyrophosphate; Purines | 1984 |
Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Azathioprine; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Culture Test, Mixed; Lymphocytes; Mercaptopurine; Xanthine; Xanthines | 1984 |
AMP metabolism in the marine bacterium Beneckea natriegens.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Inosine; Nucleotidases; Vibrio; Vibrionaceae | 1980 |
Increase of adenosine content in cerebral cortex of the cat during bicuculline-induced seizure.
Topics: Adenosine; Animals; Bicuculline; Cats; Cerebral Cortex; Female; Hypoxanthines; Inosine; Lactates; Male; Nucleotidases; Seizures | 1980 |
Different sites of adenosine formation in the heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine Monophosphate; Alkaline Phosphatase; Animals; Erythrocytes; Guanosine Monophosphate; Guinea Pigs; Hypoxanthines; Inosine; Kinetics; Myocardium; Nucleotidases | 1981 |
The use of substrates and energy in the treatment of shock.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Cyclic AMP; Dogs; Glucose; Humans; Inosine; Insulin; Niacinamide; Rabbits; Rats; Shock | 1980 |
[Purine catabolism in rat brain (author's transl)].
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Animals; Brain; Guanine Deaminase; Inosine; Kinetics; Male; Nucleotidases; Purine-Nucleoside Phosphorylase; Purines; Rats; Rats, Inbred Strains; Xanthines | 1981 |
The anatomical distribution of ADPase activity in the rabbit aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta, Abdominal; Aorta, Thoracic; Apyrase; Inosine; Male; Phosphoric Monoester Hydrolases; Rabbits | 1982 |
Tissue adenosine content in active soleus and gracilis muscles of cats.
Topics: 5'-Nucleotidase; Adenosine; AMP Deaminase; Animals; Cats; Female; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Lactates; Lactic Acid; Male; Muscle Contraction; Muscles; Nucleotidases; Nucleotide Deaminases | 1983 |
Adenosine uptake inhibitors potentiate the sedative effects of adenosine.
Topics: Adenosine; Animals; Arousal; Brain; Guanosine; Inosine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Cell Surface; Receptors, Purinergic; Synapses; Thioinosine; Thionucleosides | 1983 |
Phasic release of adenosine during steady state metabolic stimulation in the isolated guinea pig heart.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Guinea Pigs; Heart; Inosine; Male; Myocardium; Norepinephrine; Oxygen Consumption; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasodilation | 1983 |
Relationship between phosphorylation and cytotoxicity of 2-chloroadenosine and 6-methylmercaptopurine riboside in human cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Kinase; B-Lymphocytes; Cell Line; Genetic Variation; Humans; Inosine; Methylthioinosine; Phosphorylation; Phosphotransferases | 1984 |
Levels of adenosine and adenine nucleotides in slices of rat hippocampus.
Topics: Adenine Nucleotides; Adenosine; Animals; Cyclic AMP; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Inosine; Inosine Monophosphate; Kinetics; Male; Rats; Rats, Inbred Strains | 1984 |
Decreased methionine synthesis in purine nucleoside-treated T and B lymphoblasts and reversal by homocysteine.
Topics: Adenosine; B-Lymphocytes; Cell Line; Deoxyadenosines; Deoxyguanosine; Guanosine; Homocysteine; Humans; Inosine; Lymphocyte Activation; Methionine; Purine Nucleosides; T-Lymphocytes; Vidarabine | 1984 |
Adenine nucleotide levels and adenosine metabolism in cultured calvarial bone.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bone and Bones; Cells, Cultured; Deoxyadenosines; Dinoprostone; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Mice; Parathyroid Hormone; Prostaglandins E; Uric Acid | 1984 |
Evidence for distinct catabolic pathways of adenine ribonucleotides and deoxyribonucleotides in human T lymphoblastoid cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Line; Coformycin; Deoxyadenine Nucleotides; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Kinetics; Pentostatin; Structure-Activity Relationship; T-Lymphocytes | 1984 |
Enzymatic conversion of adenosine to inosine in the wobble position of yeast tRNAAsp: the dependence on the anticodon sequence.
Topics: Adenosine; Adenosine Deaminase; Animals; Anticodon; Base Sequence; Female; Inosine; Nucleic Acid Conformation; Nucleoside Deaminases; Oligoribonucleotides; Oocytes; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Xenopus | 1984 |
Stimulation of maximal intracellular insulin action on glycogen synthase by preincubation of adipocytes with adenosine 5'-triphosphate.
Topics: Adenosine; Adenosine Triphosphate; Adipose Tissue; Animals; Calcium; Drug Synergism; Glycogen Synthase; Inosine; Insulin; Magnesium; Male; Rats; Rats, Inbred Strains | 1983 |
Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells.
Topics: Adenosine; Cells, Cultured; Deoxyadenosines; Humans; Inosine; Leukemia; Leukemia, Myeloid, Acute; Methionine; Methylthioinosine; Purine-Nucleoside Phosphorylase; T-Lymphocytes; Thionucleosides | 1983 |
Specificity and control of uptake of purines and other compounds in Bacillus subtilis.
Topics: Adenine; Adenosine; Aminoisobutyric Acids; Bacillus subtilis; Biological Transport; Guanine; Guanosine; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Methylglucosides; Methylglycosides; Purines; Spores, Bacterial; Uracil | 1983 |
Mechanism of potentiation by diazepam of adenosine response.
Topics: 2-Chloroadenosine; Adenosine; Animals; Benzodiazepinones; Cecum; Diazepam; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Female; Flumazenil; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Inbred Strains | 1984 |
Ethanol-induced activation of adenine nucleotide turnover. Evidence for a role of acetate.
Topics: Acetates; Acetic Acid; Adenine; Adenine Nucleotides; Adenosine; Adult; Carbon Radioisotopes; Ethanol; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Time Factors; Xanthine; Xanthines | 1984 |
Adenosine uptake sites in dog heart and brain; interaction with calcium antagonists.
Topics: Adenosine; Animals; Blood Pressure; Brain; Calcium Channel Blockers; Coronary Circulation; Dipyridamole; Dogs; Heart Rate; Inosine; Kinetics; Myocardium; Thioinosine; Vascular Resistance | 1984 |
[3H]nitrobenzylthioinosine binding to the guinea pig CNS nucleoside transport system: a pharmacological characterization.
Topics: Adenosine; Animals; Benzodiazepines; Binding, Competitive; Biological Transport; Brain; Cell Membrane; Female; Guinea Pigs; Inosine; Kinetics; Nucleosides; Phenothiazines; Subcellular Fractions; Synaptosomes; Thioinosine | 1984 |
[Effect of papaverine on the absorption and metabolism of 14C- adenosine and 14C-adenine in thymocytes].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Carbon Radioisotopes; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Papaverine; Rats; Rats, Inbred Strains; Thymus Gland | 1984 |
Release of adenosine, inosine and hypoxanthine from rabbit non-myelinated nerve fibres at rest and during activity.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antimetabolites; Cyanides; Deoxyglucose; Glucose; Hydrolysis; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Nerve Fibers; Rabbits | 1984 |
Differential excretion of modified nucleosides in adult acute leukemia.
Topics: Adenosine; Adult; Aged; Creatinine; Female; Guanosine; Humans; Inosine; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Nucleosides | 1983 |
Adenosine antagonism as an alternative mechanism of action of methylxanthines in asthma.
Topics: Adenosine; Adenosine Monophosphate; Airway Resistance; Asthma; Bronchi; Dose-Response Relationship, Drug; Guanosine; Histamine; Humans; Inosine; Theophylline | 1983 |
Metabolism to methionine and growth stimulation by 5'-methylthioadenosine and 5'-methylthioinosine in mammalian cells.
Topics: Adenosine; Animals; B-Lymphocytes; Cell Division; Cell Line; Deoxyadenosines; Humans; Inosine; Leukemia L1210; Methionine; Methylthioinosine; Mice; Thionucleosides | 1983 |
Renal secretion of purine nucleosides and their analogs in mice.
Topics: Adenosine; Animals; Deoxyadenosines; Inosine; Kidney; Male; Mice; Purine Nucleosides; Tetraethylammonium Compounds; Tubercidin | 1983 |
Measurement of adenosine metabolism and uptake in smooth muscle and effects of adenosine transport inhibitors.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Cattle; Coformycin; Coronary Vessels; Dipyridamole; Dose-Response Relationship, Drug; Female; Guanosine; Guinea Pigs; In Vitro Techniques; Inosine; Intestinal Mucosa; Male; Muscle, Smooth; Pentostatin; Rabbits; Thioinosine; Thionucleosides | 1984 |
Thermoregulatory effects of purines and caffeine.
Topics: Adenosine; Animals; Body Temperature Regulation; Caffeine; Drug Interactions; Inosine; Male; Purine Nucleosides; Rats; Rats, Inbred Strains | 1983 |
Influence of adenosine on the vascular responses to sympathetic nerve stimulation in the canine subcutaneous adipose tissue.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Body Temperature; Dipyridamole; Dogs; Electric Stimulation; Female; Homeostasis; Inosine; Norepinephrine; Propranolol; Regional Blood Flow; Sympathetic Nervous System; Theophylline; Vascular Resistance; Vasoconstriction | 1983 |
[Changes of the acid-base status, serum lactate concentration and purine metabolism in reconstructive arterial surgery].
Topics: Acid-Base Equilibrium; Adenosine; Aorta, Abdominal; Humans; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Middle Aged; Purines; Pyruvates; Pyruvic Acid; Uric Acid; Xanthine; Xanthines | 1983 |
Kinetics of nitrobenzylthioinosine binding to the human erythrocyte nucleoside transporter.
Topics: Adenosine; Binding Sites; Carrier Proteins; Dipyridamole; Erythrocyte Membrane; Humans; In Vitro Techniques; Inosine; Kinetics; Models, Biological; Nucleosides; Protein Binding; Thioinosine; Uridine | 1983 |
Release of purine nucleosides and oxypurines from the isolated perfused rat heart.
Topics: Adenosine; Allopurinol; Animals; Constriction; Coronary Circulation; Hypoxanthine; Hypoxanthines; Inosine; Male; Myocardium; Rats; Rats, Inbred Strains; Xanthine Oxidase; Xanthines | 1983 |
Nucleoside transport. Photoaffinity labelling of high-affinity nitrobenzylthioinosine binding sites in rat and guinea pig lung.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Biological Transport; Cell Membrane; Dipyridamole; Guinea Pigs; Inosine; Kinetics; Lung; Male; Nucleosides; Rats; Rats, Inbred Strains; Thioinosine; Uridine | 1984 |
Effect of perfusate pH on coronary flow and adenosine release in isolated rabbit heart.
Topics: Adenosine; Animals; Coronary Circulation; Guinea Pigs; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Inosine; Myocardial Contraction; Myocardium; Organ Culture Techniques; Oxygen Consumption; Rabbits | 1984 |
Nucleoside transport in heart: species differences in nitrobenzylthioinosine binding, adenosine accumulation, and drug-induced potentiation of adenosine action.
Topics: Adenosine; Animals; Benzodiazepines; Biological Transport; Cattle; Drug Synergism; Guinea Pigs; In Vitro Techniques; Inosine; Male; Mice; Myocardial Contraction; Myocardium; Rabbits; Rats; Species Specificity; Thioinosine; Tritium | 1984 |
Diltiazem administered before or during myocardial ischemia decreases adenine nucleotide catabolism.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Benzazepines; Coronary Circulation; Coronary Disease; Diltiazem; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Male; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines | 1984 |
Progress curve analysis of adenosine deaminase-catalyzed reactions.
Topics: Adenosine; Adenosine Deaminase; Animals; Catalysis; Cattle; Inosine; Kinetics; Nucleoside Deaminases | 1984 |
Identification of the nucleoside transporter in cultured mouse lymphoma cells. Photoaffinity labeling of plasma membrane-enriched fractions from nucleoside transport-competent (S49) and nucleoside transport-deficient (AE1) cells with [3H]nitrobenzylthioin
Topics: Adenosine; Affinity Labels; Animals; Binding, Competitive; Blood Proteins; Cell Line; Cell Membrane; Dipyridamole; Guanosine; Inosine; Lymphoma; Membrane Proteins; Mice; Nucleoside Transport Proteins; Thioinosine; Thionucleosides; Tritium | 1984 |
Measurement of adenosine, inosine, and hypoxanthine in human plasma.
Topics: Adenosine; Blood Specimen Collection; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Inosine | 1984 |
The relationship between purines, pyrimidines, nucleosides, and glutamine for fibroblast cell proliferation.
Topics: Adenine; Adenosine; Animals; Cell Division; Cell Line; DNA; Fibroblasts; Glutamine; Hypoxanthine; Hypoxanthines; Inosine; Mice; Nucleosides; Purines; Pyrimidines | 1984 |
[Effect of myocardial ischemia on adenine nucleotide metabolism].
Topics: Adenine Nucleotides; Adenosine; Angina Pectoris; Cardiac Catheterization; Coronary Disease; Electric Stimulation; Humans; Hypoxanthines; Inosine; Middle Aged; Myocardial Infarction; Neurocirculatory Asthenia; Time Factors | 1984 |
Efflux of radioactive nucleotides from mouse pancreatic islets prelabelled with 2-3H-adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antimycin A; Cells, Cultured; Glipizide; Glucose; Inosine; Insulin; Islets of Langerhans; Keto Acids; Male; Mice; Nucleotides; Pyruvates | 1982 |
[Adenosine and its derivatives released by neocortex synaptosomes of the guinea pig].
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Cerebral Cortex; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Inosine; Synaptosomes | 1980 |
Changes in brain adenosine during bicuculline-induced seizures in rats. Effects of hypoxia and altered systemic blood pressure.
Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Brain Chemistry; Carbon Dioxide; Hydrogen-Ion Concentration; Hypoxanthines; Hypoxia; Inosine; Oxygen; Rats; Seizures | 1980 |
Localization of purine and pyrimidine nucleoside phosphorylases in heart, kidney, and liver.
Topics: Adenosine; Animals; Bile; Guinea Pigs; History, 20th Century; Hypoxanthines; Inosine; Kidney; Liver; Microscopy, Electron; Myocardium; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Pyrimidine Nucleosides; Pyrimidine Phosphorylases; Rats; Ureter | 1980 |
Kinetic alpha-deuterium isotope effects for Escherichia coli purine nucleoside phosphorylase-catalyzed phosphorolysis of adenosine and inosine.
Topics: Adenosine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Inosine; Kinetics; Molecular Conformation; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Radioisotope Dilution Technique | 1981 |
Solubilization of murine melanoma xylosyltransferase and galactosyltransferase activities and their inactivation by dialdehyde nucleosides.
Topics: Adenosine; Aldehydes; Animals; Cell Fractionation; Cell Line; Cytidine; Galactosyltransferases; Hydrogen-Ion Concentration; Inosine; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Octoxynol; Pentosyltransferases; Polyethylene Glycols; Potassium Chloride; Pyridoxal Phosphate; UDP Xylose-Protein Xylosyltransferase; Uridine | 1982 |
Relationship between myocardial oxygen consumption, coronary flow, and adenosine release in an improved isolated working heart preparation of guinea pigs.
Topics: Adenosine; Animals; Coronary Circulation; Guinea Pigs; Heart; Hypoxanthines; Inosine; Isoproterenol; Myocardium; Oxygen Consumption; Perfusion; Stroke Volume; Vascular Resistance | 1983 |
Validity of the continuous spectrophotometric assay of Kalckar for adenosine deaminase activity.
Topics: Adenosine; Adenosine Deaminase; Inosine; Nucleoside Deaminases; Spectrophotometry, Ultraviolet | 1983 |
Metabolism of circulating adenosine by the porcine isolated perfused lung.
Topics: Adenine Nucleotides; Adenosine; Animals; Dipyridamole; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lung; Perfusion; Swine; Tubercidin | 1983 |
Circadian variations of adenosine level in blood and liver and its possible physiological significance.
Topics: Adenosine; Animals; Circadian Rhythm; Energy Metabolism; Hypoxanthine; Hypoxanthines; Inosine; Liver; Male; Phosphorylation; Purines; Rats; Rats, Inbred Strains; Uric Acid | 1983 |
Altered RNA/protein ratio associated with the induction of differentiation of Friend erythroleukemia cells.
Topics: Adenosine; Adenosine Triphosphate; Animals; Butyrates; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Friend murine leukemia virus; Guanosine Triphosphate; Inosine; Leukemia, Erythroblastic, Acute; Mice; Neoplasm Proteins; Puromycin Aminonucleoside; RNA, Neoplasm | 1981 |
HPLC analysis of aromatic amino acids, nucleosides, and bases in plasma of acute lymphocytic leukemia on chemotherapy.
Topics: Adenosine; Amino Acids; Chromatography, High Pressure Liquid; Guanosine; Humans; Hypoxanthines; Inosine; Leukemia, Lymphoid; Nucleosides; Phenylalanine; Tyrosine; Xanthines | 1982 |
Metabolism of adenosine and 2'-deoxy-adenosine by fetal mouse calvaria in culture.
Topics: Adenine; Adenosine; Animals; Bone and Bones; Culture Media; Deoxyadenosines; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Inosine; Mice; Organ Culture Techniques | 1982 |
Purine base and nucleoside uptake in Plasmodium berghei and host erythrocytes.
Topics: Adenine; Adenosine; Animals; Biological Transport, Active; Diffusion; Erythrocytes; Hypoxanthines; Inosine; Kinetics; Male; Plasmodium berghei; Purine Nucleosides; Purines; Rats | 1980 |
Adenylate degradation in Escherichia coli. The role of AMP nucleosidase and properties of the purified enzyme.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Escherichia coli; Hypoxanthines; Inosine; Kinetics; Molecular Weight; Mutation; N-Glycosyl Hydrolases; Phosphates | 1980 |
Azidopolynucleotides as photoaffinity reagents.
Topics: Adenosine; Adenosine Monophosphate; Affinity Labels; Azides; Binding Sites; DNA-Directed RNA Polymerases; Escherichia coli; Inosine; Inosine Monophosphate; Inosine Nucleotides; Kinetics; Poly C; Poly U; Polyribonucleotide Nucleotidyltransferase; Polyribonucleotides; Protein Binding; Transcription, Genetic | 1980 |
Uridine and uracil transport in Escherichia coli and transport-deficient mutants.
Topics: Adenine; Adenosine; Biological Transport; Escherichia coli; Guanine; Hypoxanthines; Inosine; Kinetics; Mutation; Species Specificity; Thymine; Uracil; Uridine | 1981 |
Benzodiazepines are weak inhibitors of [3H]nitrobenzylthioinosine binding to adenosine uptake sites in brain.
Topics: Adenosine; Animals; Benzodiazepines; Binding Sites; Brain; Cell Membrane; Inosine; Male; Rats; Rats, Inbred Strains; Synaptosomes; Thioinosine; Tritium | 1982 |
Interactions between inosine and adenosine: experimental researches.
Topics: Adenosine; Animals; Drug Interactions; Duodenum; Female; Heart; In Vitro Techniques; Inosine; Male; Mice; Myocardium; N-Glycosyl Hydrolases; Ranidae; Rats; Uterus | 1982 |
[3H]nitrobenzylthioinosine binding as a probe for the study of adenosine uptake sites in brain.
Topics: Adenosine; Animals; Biological Transport; Brain; Caudate Nucleus; Cell Membrane; Heart; Humans; Hypothalamus; Inosine; Kinetics; Male; Rats; Rats, Inbred Strains; Synaptosomes; Thioinosine; Tissue Distribution; Tritium | 1982 |
Purine levels in the intact rat brain. Studies with an implanted perfused hollow fibre.
Topics: Adenine; Adenosine; Animals; Brain; Chromatography, High Pressure Liquid; Guanosine; Hypoxanthines; Inosine; Male; Purines; Rats; Rats, Inbred Strains | 1982 |
Origin of adenosine released from rat vas deferens by nerve stimulation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cytoplasmic Granules; Dipyridamole; Electric Stimulation; In Vitro Techniques; Inosine; Male; Muscle, Smooth; Norepinephrine; Rats; Subcellular Fractions; Sympathetic Nervous System; Vas Deferens | 1982 |
[Excretion of methylated nucleosides in the initial therapy phase in a case of anorexia nervosa].
Topics: Adenosine; Adolescent; Anorexia Nervosa; Female; Guanosine; Humans; Inosine; Nucleosides; Uridine | 1982 |
Role of mitochondrial oxidative phosphorylation in regulation of coronary blood flow.
Topics: Adenosine; Amobarbital; Animals; Calcium; Coronary Circulation; Hypoxanthines; Hypoxia; Inosine; Lactates; Lactic Acid; Male; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; Phosphates; Physical Exertion; Rats; Theophylline | 1982 |
Rat adipocyte lipoprotein lipase activity is inhibited by theophylline and stimulated by inosine through adenosine-independent mechanisms.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Inosine; Kinetics; Lipoprotein Lipase; Male; Rats; Rats, Inbred Strains; Theophylline | 1982 |
The specificity of purine base and nucleoside uptake in promastigotes of Leishmania braziliensis panamensis.
Topics: Adenine; Adenosine; Animals; Biological Transport; Hypoxanthines; Inosine; Kinetics; Leishmania; Purine Nucleosides; Purines | 1982 |
[3H]nitrobenzylthioinosine is a photoaffinity probe for adenosine uptake sites in brain.
Topics: Adenosine; Affinity Labels; Animals; Brain; In Vitro Techniques; Inosine; Rats; Thioinosine; Tritium | 1982 |
Nucleoside transport in rat cerebral cortical synaptosomal membrane: a high affinity probe study.
Topics: Adenosine; Animals; Binding Sites; Biological Transport; Cerebral Cortex; Inosine; Male; Rats; Rats, Inbred Strains; Synaptic Membranes; Synaptosomes; Thioinosine | 1982 |
Structures of neplanocins, new antitumor antibiotics.
Topics: Adenosine; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Inosine; Magnetic Resonance Spectroscopy; Purine Nucleosides; Structure-Activity Relationship | 1980 |
Hypoxanthine production by ischemic heart demonstrated by high pressure liquid chromatography of blood purine nucleosides and oxypurines.
Topics: Adenosine; Angina Pectoris; Chromatography, High Pressure Liquid; Clinical Laboratory Techniques; Coronary Disease; Erythrocytes; Humans; Hypoxanthines; Inosine; Lactates; Lactic Acid; Plasma; Purine Nucleosides; Xanthines | 1981 |
Adenosine metabolism in dog whole blood: effects of dipyridamole.
Topics: Adenosine; Animals; Dipyridamole; Dogs; Female; Half-Life; Inosine; Male | 1981 |
Radioisotopic microassay of adenosine deaminase in human lymphocytes.
Topics: Adenosine; Adenosine Deaminase; Humans; Inosine; Lymphocytes; Microchemistry; Nucleoside Deaminases | 1980 |
Passive diffusion of nucleosides into Micrococcus sodonensis membrane vesicles.
Topics: Adenosine; Biological Transport; Cell Membrane; Cytidine; Diffusion; Inosine; Micrococcus; Nucleosides; Thymidine; Uridine | 1980 |
The release of adenosine and inosine from canine subcutaneous adipose tissue by nerve stimulation and noradrenaline.
Topics: Adenosine; Adipose Tissue; Animals; Dogs; Female; Inosine; Norepinephrine; Sympathetic Nervous System | 1981 |
Electroshock seizures in mice: effect on brain adenosine and its metabolites.
Topics: Adenosine; Animals; Brain; Disease Models, Animal; Electric Stimulation; Hypoxanthines; Inosine; Mice; Seizures | 1981 |
Role of adenosine in adipose tissue circulation.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Capillary Permeability; Dilazep; Dipyridamole; Dogs; Female; Inosine; Vascular Resistance; Vasodilator Agents | 1981 |
Gluconeogenesis from Nucleosides in perfused rat livers.
Topics: Adenosine; Adenosine Monophosphate; Animals; Fasting; Gluconeogenesis; Glucose; Glycogen; In Vitro Techniques; Inosine; Kinetics; Liver; Liver Circulation; Male; Nucleosides; Rats; Rats, Inbred Strains; Species Specificity | 1981 |
The interaction of inhibitors with adenosine metabolising enzymes in intact isolated cells.
Topics: Adenosine; Adenosine Deaminase; Animals; Cells, Cultured; Inosine; Neutrophils; Rats; Spleen | 1981 |
Absence of binding sites for the transport inhibitor nitrobenzylthioinosine on nucleoside transport-deficient mouse lymphoma cells.
Topics: Adenosine; Animals; Anti-Bacterial Agents; Biological Transport; Cell Division; Cell Line; Clone Cells; Inosine; Kinetics; Lymphoma; Mice; Neoplasms, Experimental; Ribonucleosides; Thioinosine | 1981 |
Effect of adenosine metabolites on methyltransferase reactions in isolated rat livers.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Animals; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Liver; Male; Methyltransferases; Perfusion; Rats; S-Adenosylhomocysteine; Uric Acid | 1981 |
Analysis of adenosine, inosine and hypoxanthine in suspensions of cardiac myocytes by high-performance liquid chromatography.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Hypoxanthines; Inosine; Myocardium; Rats | 1981 |
Effect of varying pH [H+] on the metabolism of adenosine in isolated heart cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Chick Embryo; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Myocardium; Theophylline | 1980 |
Effect of adenosine on sinoatrial and ventricular automaticity of the guinea pig.
Topics: Action Potentials; Adenosine; Animals; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Inosine; Male; Membrane Potentials; Purkinje Fibers; Sinoatrial Node | 1980 |
Incorporation of adenosine and its metabolites into brain nucleotides.
Topics: Adenosine; Animals; Blood-Brain Barrier; Brain; Dogs; Hypoxanthines; Inosine; Nucleotides | 1980 |
Brain adenosine production in rat during sustained alteration in systemic blood pressure.
Topics: Adenine Nucleotides; Adenosine; Animals; Blood Pressure; Brain; Hypoxanthines; Inosine; Lactates; Phosphocreatine; Rats | 1980 |
Uptake of purine bases and nucleosides in African trypanosomes.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Guanosine; Hypoxanthines; Inosine; Kinetics; Purines; Trypanosoma; Trypanosoma brucei brucei | 1980 |
Inotropic and chronotropic responses to inosine in isolated and blood-perfused dog atria.
Topics: Acetylcholine; Adenosine; Animals; Atropine; Dogs; Female; Heart Atria; Heart Rate; In Vitro Techniques; Inosine; Male; Myocardial Contraction; Norepinephrine; Perfusion; Propranolol | 1980 |
The characterization of [3H] adenosine uptake into rat cerebral cortical synaptosomes.
Topics: Adenosine; Animals; Biological Transport, Active; Calcium; Cerebral Cortex; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Male; Rats; Sodium; Synaptosomes; Temperature | 1980 |
The dephosphorylation of AMP and IMP by a soluble low Km 5'nucleotidase from human seminal plasma: some regulatory aspects.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Male; Phosphates; Semen; Solubility | 1995 |
A novel enzymatic pathway leading to 1-methylinosine modification in Haloferax volcanii tRNA.
Topics: Adenosine; Base Sequence; Halobacteriaceae; Inosine; Molecular Sequence Data; Nucleosides; Pseudouridine; RNA Processing, Post-Transcriptional; RNA, Bacterial; RNA, Transfer, Ile; Subcellular Fractions | 1995 |
3-isobutyl-1-methylxanthine decreases renal cortical interstitial levels of adenosine and inosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Blood Pressure; Extracellular Space; Inosine; Kidney Cortex; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1994 |
Preferential selection of adenosines for modification by double-stranded RNA adenosine deaminase.
Topics: Adenosine; Adenosine Deaminase; Base Sequence; Deamination; Endoribonucleases; Inosine; Molecular Sequence Data; Oligoribonucleotides; Receptors, Glutamate; Ribonuclease T1; RNA; RNA Editing; RNA-Binding Proteins | 1994 |
Homocysteine enhances the inhibitory effect of extracellular adenosine on the synthesis of proteins in isolated rat hepatocytes.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Survival; Cells, Cultured; Drug Synergism; Homocysteine; Hydrolases; Inosine; Kinetics; Liver; Male; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1995 |
Microdialyzed adenosine in nucleus tractus solitarii and ventilatory response to hypoxia in piglets.
Topics: Adenosine; Animals; Blood Pressure; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Microdialysis; Respiratory Mechanics; Solitary Nucleus; Spectrophotometry, Ultraviolet; Swine; Swine, Miniature | 1995 |
Intermittent aortic crossclamping prevents cumulative adenosine triphosphate depletion, ventricular fibrillation, and dysfunction (stunning): is it preconditioning?
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Aorta; Constriction; Dogs; Inosine; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Thioinosine; Ventricular Dysfunction, Left; Ventricular Fibrillation; Ventricular Function, Left | 1995 |
Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Guinea Pigs; Heart; Inosine; Lactates; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Phosphorylation; Theophylline | 1995 |
Adenosine uptake and metabolism in human endothelial cells.
Topics: Adenine Nucleotides; Adenosine; Biological Transport; Cells, Cultured; Endothelium, Vascular; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Umbilical Veins | 1994 |
Inhibition of nucleoside transport by reactive oxygen species in bovine heart microvascular endothelial cells.
Topics: Adenosine; Animals; Biological Transport; Cattle; Cell Line; Dipyridamole; Endothelium, Vascular; Heart; Hydrogen Peroxide; Hypochlorous Acid; Inosine; Kinetics; Nucleosides; Reactive Oxygen Species; Thioinosine; Uridine; Vitamin K | 1994 |
Editing of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR-B pre-mRNA in vitro reveals site-selective adenosine to inosine conversion.
Topics: Adenosine; Base Sequence; HeLa Cells; Humans; Inosine; Molecular Sequence Data; Receptors, AMPA; RNA Editing; RNA Precursors; RNA, Messenger | 1995 |
Hydrolytic cleavage of purine ribonucleosides by extracts of Aspergillus terricola.
Topics: Adenosine; Aspergillus; Cobalt; Copper; Copper Sulfate; Guanosine; Hydrogen-Ion Concentration; Hydrolysis; Inosine; Kinetics; Purine Nucleosides; Ribonucleases; Temperature | 1994 |
Abundance of guanine, guanosine, inosine and adenosine in human seminal plasma.
Topics: Adenosine; Chromatography, High Pressure Liquid; Guanine; Guanosine; Humans; Inosine; Male; Ribonucleosides; Semen; Sperm Count; Vasectomy | 1995 |
Continuous monitoring of energy metabolites using microdialysis during myocardial ischaemia in the pig.
Topics: Adenosine; Animals; Energy Metabolism; Female; Guanosine; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyruvates; Pyruvic Acid; Swine | 1995 |
Amino acid and purine release in rat brain following temporary middle cerebral artery occlusion.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Arteries; Constriction; Excitatory Amino Acids; gamma-Aminobutyric Acid; Inosine; Male; Purines; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Pre-steady-state transition-state analysis of the hydrolytic reaction catalyzed by purine nucleoside phosphorylase.
Topics: Adenosine; Animals; Arsenates; Carbon Radioisotopes; Cattle; Electrochemistry; Hydrolysis; Inosine; Kinetics; Models, Molecular; Molecular Structure; Purine-Nucleoside Phosphorylase; Substrate Specificity; Tritium; Water | 1995 |
Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices.
Topics: Adenosine; Adenosine Kinase; Animals; Hippocampus; In Vitro Techniques; Inosine; Kinetics; Membrane Potentials; Neurons; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Tubercidin; Xanthines | 1994 |
Reversal of methylmercaptopurine ribonucleoside cytotoxicity by purine ribonucleosides and adenine.
Topics: Adenine; Adenosine; Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Guanosine; Humans; Inosine; Mercaptopurine; Methylthioinosine; Nucleosides; Nucleotides; Purine Nucleosides; Ribonucleosides; T-Lymphocytes; Thioinosine; Thionucleotides | 1995 |
Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosine.
Topics: Adenosine; Adenosine Deaminase; Base Sequence; Deamination; DNA; Electrophysiology; HeLa Cells; Humans; Inosine; Molecular Sequence Data; Mutagenesis; Nucleic Acid Conformation; Polymerase Chain Reaction; Receptors, Glutamate; RNA Editing; RNA Precursors; Tumor Cells, Cultured | 1995 |
Glutamate receptor RNA editing in vitro by enzymatic conversion of adenosine to inosine.
Topics: Adenosine; Animals; Base Sequence; Cell Line; Codon; Exons; HeLa Cells; Humans; Inosine; Inosine Monophosphate; Mice; Molecular Sequence Data; Rats; Receptors, AMPA; Repetitive Sequences, Nucleic Acid; RNA Editing; RNA Precursors; RNA, Double-Stranded; Tumor Cells, Cultured | 1995 |
Comparison of energy metabolism in rat liver grafts during preservation in University of Wisconsin or Euro-Collins solutions.
Topics: Adenosine; Allopurinol; Animals; Energy Metabolism; Glutathione; Hypertonic Solutions; Hypoxanthine; Hypoxanthines; Inosine; Insulin; Lactates; Liver; Liver Transplantation; Male; Microdialysis; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Time Factors; Uric Acid; Xanthine; Xanthines | 1995 |
Low energy charge and high adenosine content in smooth muscle of human bladder in comparison with striated muscle.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Aged; Female; Humans; Inosine; Middle Aged; Muscle, Smooth; Rectus Abdominis; Urinary Bladder; Urinary Incontinence, Stress | 1994 |
An invariant asparagine in the POU-specific homeodomain regulates the specificity of the Oct-2 POU motif.
Topics: Adenosine; Asparagine; Base Sequence; DNA; DNA Mutational Analysis; DNA-Binding Proteins; Gene Expression Regulation; Genes, Homeobox; Inosine; Molecular Sequence Data; Protein Binding; Structure-Activity Relationship; Transcription Factors | 1994 |
Uptake, transport and metabolism of exogenous nucleosides in intestinal epithelial cell cultures.
Topics: Adenosine; Biological Transport; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Cytidine; Electric Conductivity; Epithelium; Guanosine; Humans; Inosine; Intestinal Mucosa; Intestinal Neoplasms; Kinetics; Nucleosides; Thymidine | 1994 |
Pentostatin-augmented interstitial adenosine prevents postcardioplegia injury in damaged hearts.
Topics: Adenosine; Animals; Creatine Kinase; Dogs; Heart Arrest, Induced; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Microdialysis; Models, Biological; Myocardial Reperfusion Injury; Pentostatin; Peroxidase; Premedication; Stroke Volume; Ventricular Function, Left; Xanthine; Xanthines | 1994 |
Changes in interstitial adenosine during hypoxia: relationship to oxygen supply:demand imbalance, and effects of adenosine deaminase.
Topics: Acute Disease; Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Dogs; Extracellular Space; Female; Hypoxanthines; Hypoxia; Inosine; Male; Myocardium; Oxygen; Xanthines | 1994 |
Effect of hypoglycemia on postischemic cortical blood flow, hypercapnic reactivity, and interstitial adenosine concentration.
Topics: Adenosine; Animals; Animals, Newborn; Blood Pressure; Brain Ischemia; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Extracellular Space; Hypercapnia; Hypoglycemia; Hypoxanthine; Hypoxanthines; Inosine; Swine; Xanthine; Xanthines | 1994 |
Cardiac storage with UW solution and glucose.
Topics: Adenine Nucleotides; Adenosine; Allopurinol; Animals; Coronary Circulation; Glucose; Glutathione; Heart Transplantation; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Insulin; Myocardium; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Ventricular Function | 1994 |
Adenosine metabolism in vivo.
Topics: Adenosine; Animals; Cats; Chromatography, High Pressure Liquid; Female; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Male; Uric Acid | 1994 |
Nucleoside trapping during reperfusion prevents ventricular dysfunction, "stunning," in absence of adenosine. Possible separation between ischemic and reperfusion injury.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Biological Transport, Active; Dogs; Female; Inosine; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Purinones; Random Allocation; Thioinosine; Ventricular Function, Left | 1994 |
Separation between ischemic and reperfusion injury by site specific entrapment of endogenous adenosine and inosine using NBMPR and EHNA.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Dogs; Female; Heart; Inosine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Thioinosine; Ventricular Function, Left | 1994 |
Purine- and nucleotide-mediated relaxation of rabbit thoracic aorta: common and different sites of action.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nucleotides; Purines; Rabbits; Suramin; Uridine Triphosphate; Vasodilator Agents | 1994 |
Existence and role of substrate cycling between AMP and adenosine in isolated rabbit cardiomyocytes under control conditions and in ATP depletion.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adenosylhomocysteinase; Animals; Cell Separation; Hydrolases; Inosine; Iodoacetates; Iodoacetic Acid; Male; Myocardium; Osmolar Concentration; Rabbits; Reference Values | 1994 |
Adenosine inhibition of beta-adrenergic induced responses in aged hearts.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adrenergic beta-Antagonists; Aging; Animals; Coronary Vessels; Cyclic AMP; Extracellular Space; Heart; In Vitro Techniques; Inosine; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphorylases; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1993 |
Differences in purine metabolism in patients with Down's syndrome.
Topics: Adenosine; Adolescent; Child; Chromosomes, Human, Pair 21; Down Syndrome; Female; Folic Acid; Guanosine; Humans; Inosine; Male; Mitotic Index; Phenotype; Purines | 1993 |
High adenosine content in human uterine smooth muscle compared with striated skeletal muscle.
Topics: Adenosine; Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Hypoxanthines; Inosine; Middle Aged; Myometrium; Phosphates; Postmenopause; Pregnancy; Rectus Abdominis; Xanthine; Xanthines | 1993 |
Adenosine: differential effect on blood flow to subregions of the upper gastrointestinal tract.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Duodenum; Esophagus; Gastric Fundus; Gastric Mucosa; Ileum; Inosine; Intestine, Small; Jejunum; Mucous Membrane; Muscle, Smooth; Organ Specificity; Purinergic P1 Receptor Antagonists; Pyloric Antrum; Rabbits; Receptors, Purinergic P1; Regional Blood Flow; Theophylline; Vasodilator Agents | 1994 |
Adenosine is a key component in preservation of ischemically damaged canine pancreas by the two-layer cold storage method.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cold Temperature; Dogs; Female; Graft Survival; Hypertonic Solutions; Hypoxanthine; Hypoxanthines; Inosine; Ischemia; Kinetics; Male; Organ Preservation; Pancreas; Pancreas Transplantation; Time Factors | 1994 |
Effect of ischemic preconditioning on interstitial purine metabolite and lactate accumulation during myocardial ischemia.
Topics: Adenosine; Animals; Dogs; Extracellular Space; Female; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Purines; Time Factors | 1994 |
Nucleoside-induced arteriolar constriction: a mast cell-dependent response.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Arterioles; Cricetinae; Dose-Response Relationship, Drug; In Vitro Techniques; Inosine; Male; Mast Cells; Mesocricetus; Methylene Blue; Mouth; Muscle, Smooth, Vascular; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Antagonists; Thioinosine; Vasoconstriction | 1994 |
Purine nucleotide levels in host tissues of Ehrlich ascites tumor-bearing mice in different growth phases of the tumor.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Chromatography, High Pressure Liquid; Female; Guanine Nucleotides; Guanosine; Inosine; Kinetics; Liver; Mice; Mice, Inbred ICR; Muscles; Purine Nucleotides; Time Factors | 1993 |
Interstitial purine metabolites and lactate during regional myocardial hypoxia.
Topics: Adenosine; Animals; Cardiomyopathies; Coronary Circulation; Dialysis; Dogs; Extracellular Space; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Lactates; Lactic Acid; Male; Oxygen Consumption; Purines; Xanthine; Xanthines | 1993 |
Effects of inosine on adenosine-induced coronary vasodilation in the open chest dog.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Heart; Heart Conduction System; Heart Rate; Hypoxanthines; Infusions, Intra-Arterial; Inosine; Male; Myocardium; Theophylline; Vasodilation | 1993 |
Effect of idebenone on adenosine outflow and adenine nucleotide level in hippocampal slices under ischemia-like conditions.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzoquinones; Brain Ischemia; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Inosine; Male; Rats; Rats, Wistar; Ubiquinone | 1993 |
Gas chromatography/mass spectrometric analysis of urinary nucleosides in cancer patients; potential of modified nucleosides as tumour markers.
Topics: Adenosine; Biomarkers, Tumor; Female; Gas Chromatography-Mass Spectrometry; Guanosine; Humans; Inosine; Male; Neoplasms; Nucleosides | 1993 |
Day-night variations of adenosine and its metabolizing enzymes in the brain cortex of the rat--possible physiological significance for the energetic homeostasis and the sleep-wake cycle.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosylhomocysteinase; Animals; Cerebral Cortex; Circadian Rhythm; Energy Metabolism; Homeostasis; Hydrolases; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; Sleep; Wakefulness | 1993 |
Effect of standard-dose versus high-dose epinephrine on myocardial high-energy phosphates during ventricular fibrillation and closed-chest CPR.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biopsy; Blood Gas Analysis; Cardiopulmonary Resuscitation; Chromatography, High Pressure Liquid; Clinical Protocols; Disease Models, Animal; Drug Evaluation, Preclinical; Epinephrine; Guanosine Triphosphate; Heart Arrest; Hemodynamics; Injections, Intravenous; Inosine; Inosine Monophosphate; Myocardium; Phosphocreatine; Swine; Ventricular Fibrillation | 1993 |
Effect of diets containing adenosine, guanosine, inosine or xanthosine on the nucleotide content of Artemia. Influence of mycophenolic acid.
Topics: Adenosine; Animals; Artemia; Diet; Guanosine; Inosine; Larva; Mycophenolic Acid; Purine Nucleosides; Ribonucleosides; Xanthines | 1993 |
Halothane reduces release of adenosine, inosine, and lactate with ischemia and reperfusion in isolated hearts.
Topics: Adenosine; Animals; Coronary Circulation; Guinea Pigs; Halothane; Heart; Inosine; Lactates; Myocardial Reperfusion; Myocardium; Oxygen Consumption | 1993 |
Arsenical-resistant trypanosomes lack an unusual adenosine transporter.
Topics: Adenine; Adenosine; Animals; Antiprotozoal Agents; Arsenicals; Biological Transport; Carrier Proteins; Drug Resistance; Inosine; Kinetics; Melarsoprol; Trypanosoma brucei brucei | 1993 |
Increases in interstitial adenosine and cerebral blood flow with inhibition of adenosine kinase and adenosine deaminase.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Brain; Cerebrovascular Circulation; Dialysis Solutions; Dose-Response Relationship, Drug; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; Tubercidin | 1993 |
Attenuation of ischemia-induced extracellular adenosine accumulation by homocysteine.
Topics: Adenosine; Analysis of Variance; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Extracellular Space; Homocysteine; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine | 1993 |
Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia.
Topics: Adenine; Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Pia Mater; Rats; Rats, Sprague-Dawley; Vasodilation | 1993 |
Pseudomonas aeruginosa exotoxin A enhances automaticity and potentiates hypoxic depression of isolated rat hearts.
Topics: Adenosine; ADP Ribose Transferases; Animals; Bacterial Toxins; Blood Pressure; Dose-Response Relationship, Drug; Drug Synergism; Exotoxins; Heart Rate; Hypoxia; Inosine; Isoproterenol; Male; Myocardial Contraction; Oxygen Consumption; Poly(ADP-ribose) Polymerases; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Resistance; Virulence Factors | 1993 |
Changes in extracellular adenosine levels and population spike amplitude during graded hypoxia in the rat hippocampal slice.
Topics: Action Potentials; Adenosine; Animals; Dipyridamole; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Inosine; Male; Picrotoxin; Rats; Rats, Sprague-Dawley | 1993 |
Assessment of purine metabolism in human renal transplantation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Biopsy; Cold Temperature; Energy Metabolism; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kidney Cortex; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Organ Preservation; Purines; Reperfusion | 1993 |
Functional and biochemical effects of a K(+)-ionophore on the isolated perfused rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Heart; Inosine; Inosine Monophosphate; Lactates; Male; Myocardium; Perfusion; Phosphofructokinase-1; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Rheology; Valinomycin | 1993 |
Effect of adenosine on glucose metabolism of Rana ridibunda erythrocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Erythrocytes; Glycolysis; Inosine; Iodoacetates; Iodoacetic Acid; Lactates; Lactic Acid; Ouabain; Rana ridibunda | 1993 |
Purine nucleoside formation in rat skeletal muscle fiber types.
Topics: Adenine Nucleotides; Adenosine; Animals; Electric Stimulation; Inosine; Inosine Monophosphate; Ischemia; Kinetics; Muscle Contraction; Muscles; Purine Nucleosides; Purines; Rats; Rats, Sprague-Dawley; Tibial Nerve; Time Factors | 1993 |
Investigations into the adenosine outflow from hippocampal slices evoked by ischemia-like conditions.
Topics: 5'-Nucleotidase; Adenosine; Amino Acids; Animals; Brain Ischemia; Calcium; Electric Stimulation; Electrophysiology; Hippocampus; In Vitro Techniques; Inosine; Male; Rats; Rats, Wistar; Tetrodotoxin | 1993 |
RNA editing. The long and the short of it.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Hepatitis Delta Virus; Humans; Inosine; Molecular Sequence Data; Nucleic Acid Conformation; Receptors, Neurotransmitter; RNA; RNA Editing; RNA-Binding Proteins; RNA, Viral | 1996 |
RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Cell Line; Deamination; Hepatitis Delta Virus; Humans; Inosine; Molecular Sequence Data; Mutation; RNA Editing; RNA-Binding Proteins; RNA, Viral; Xenopus laevis | 1996 |
Simultaneous determination of adenosine, inosine, hypoxanthine, xanthine, and uric acid in microdialysis samples using microbore column high-performance liquid chromatography with a diode array detector.
Topics: Adenosine; Animals; Calibration; Chromatography, High Pressure Liquid; Dogs; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Microdialysis; Myocardial Reperfusion Injury; Sensitivity and Specificity; Time Factors; Uric Acid; Xanthine; Xanthines | 1996 |
Enzyme-substrate complexes of adenosine and cytidine deaminases: absence of accumulation of water adducts.
Topics: Adenosine; Adenosine Deaminase; Binding Sites; Cytidine; Cytidine Deaminase; Inosine; Magnetic Resonance Spectroscopy; Substrate Specificity; Water | 1996 |
Kinetics of phosphorolysis of 3-(beta-D-ribofuranosyl)adenine and 3-(beta-D-ribofuranosyl)hypoxanthine, non-conventional substrates of purine-nucleoside phosphorylase.
Topics: Adenosine; Animals; Cattle; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Inosine; Kinetics; Protein Binding; Purine-Nucleoside Phosphorylase; Substrate Specificity | 1996 |
Adenosine-mediated inhibition of casein production by mouse mammary glands in culture.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Caseins; Culture Techniques; Cyclic AMP; Dinoprostone; Epinephrine; Female; Hydrocortisone; Inosine; Mammary Glands, Animal; Mice; Mice, Inbred BALB C; Pertussis Toxin; Phenylisopropyladenosine; Phosphodiesterase Inhibitors; Prolactin; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Virulence Factors, Bordetella | 1996 |
[Effect of dl-3-n-butylphthalide (NBP) on purine metabolites in striatum extracellular fluid in four-vessel occlusion rats].
Topics: Adenosine; Animals; Benzofurans; Brain Ischemia; Corpus Striatum; Extracellular Space; Inosine; Male; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion; Stereoisomerism; Xanthines | 1996 |
Does the internal thoracic artery graft delay the recovery of myocardial metabolism?
Topics: Adenine Nucleotides; Adenosine; Coronary Artery Bypass; Female; Heart Arrest, Induced; Humans; Hypoxanthine; Inosine; Male; Middle Aged; Myocardium; Saphenous Vein; Thoracic Arteries; Vascular Patency; Xanthine; Xanthines | 1996 |
Determination of the kinetic parameters of adenosine deaminase by electrophoretically mediated microanalysis.
Topics: Adenosine; Adenosine Deaminase; Animals; Cattle; Electrochemistry; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Inosine; Kinetics; Microchemistry; Temperature | 1996 |
Cerebral energy metabolism during severe ischemia of varying duration and following reperfusion.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Cerebral Cortex; Energy Metabolism; Inosine; Ischemic Attack, Transient; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors | 1996 |
Inosine mediates the protective effect of adenosine in rat astrocyte cultures subjected to combined glucose-oxygen deprivation.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Astrocytes; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Glucose; Inosine; Kinetics; L-Lactate Dehydrogenase; Purines; Rats; Rats, Sprague-Dawley | 1996 |
Temporal variations of adenosine metabolism in human blood.
Topics: 5'-Nucleotidase; Acclimatization; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adenosylhomocysteinase; Adult; Analysis of Variance; Blood Glucose; Circadian Rhythm; Humans; Hydrolases; Hypoxanthine; Inosine; Lactates; Male; Uric Acid | 1996 |
Mechanism, specificity and general properties of the yeast enzyme catalysing the formation of inosine 34 in the anticodon of transfer RNA.
Topics: Adenosine; Adenosine Deaminase; Anticodon; Base Sequence; Chromatography, Liquid; Chromatography, Thin Layer; Humans; Inosine; Kinetics; Magnesium; Molecular Sequence Data; Nucleic Acid Conformation; Pentostatin; RNA, Fungal; RNA, Transfer; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae | 1996 |
Cyclic AMP-adenosine pathway inhibits vascular smooth muscle cell growth.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cardiovascular Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP; DNA; Inosine; Male; Muscle Development; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley | 1996 |
A comparison of AMP degradation in the perfused rat heart during 2-deoxy-D-glucose perfusion and anoxia. Part I: The release of adenosine and inosine.
Topics: Adenosine; Adenosine Monophosphate; Animals; Antimetabolites; Deoxyglucose; Glucose; Glucose-6-Phosphate; Heart; Hemodynamics; Hypoxia; In Vitro Techniques; Inosine; Male; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Sodium Acetate | 1996 |
Kainate-evoked release of adenosine from the hippocampus of the anaesthetised rat: possible involvement of free radicals.
Topics: Adenosine; Animals; Free Radicals; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Rats; Rats, Wistar; Receptors, Amino Acid; Time Factors; Xanthine; Xanthines | 1997 |
Attenuated purine production during subsequent ischemia in preconditioned rabbit myocardium is unrelated to the mechanism of protection.
Topics: Adenosine; Animals; Female; Heart; Hemodynamics; Hypoxanthines; In Vitro Techniques; Inosine; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Myocardium; Phenylephrine; Purinergic P1 Receptor Antagonists; Purines; Rabbits; Receptors, Purinergic P1; Theophylline | 1996 |
Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis.
Topics: Adenosine; Adenosine Deaminase; Caffeine; Dipyridamole; Humans; Inosine; Leukocytes, Mononuclear; Lipopolysaccharides; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Rolipram; Tumor Necrosis Factor-alpha; Xanthines | 1997 |
Insights into thymic purine metabolism and adenosine deaminase deficiency revealed by transgenic mice overexpressing ecto-5'-nucleotidase (CD73).
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Animals; Antibodies, Monoclonal; Apoptosis; Female; Immunity, Innate; Immunoglobulins; Immunophenotyping; Inosine; Lymphocyte Activation; Lymphoid Tissue; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Purinergic P1 Receptor Agonists; Purines; Radiation Chimera; Reproduction; Survival Analysis; T-Lymphocyte Subsets; Thymus Gland; Transgenes | 1997 |
Purification and characterization of a human RNA adenosine deaminase for glutamate receptor B pre-mRNA editing.
Topics: Adenosine; Adenosine Deaminase; Base Sequence; Cloning, Molecular; HeLa Cells; Humans; Inosine; Molecular Sequence Data; Mutation; Receptors, Glutamate; Recombinant Proteins; RNA Editing; RNA Precursors; RNA-Binding Proteins; RNA, Messenger; Substrate Specificity | 1997 |
Infarct size reduction with the nucleoside transport inhibitor R-75231 in swine.
Topics: Adenosine; Animals; Blood Pressure; Cardiotonic Agents; Coronary Circulation; Female; Heart Rate; Hemodynamics; Inosine; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Piperazines; Swine; Time Factors; Ventricular Function, Left | 1997 |
Regulation of serotonin-2C receptor G-protein coupling by RNA editing.
Topics: 3T3 Cells; Adenosine; Adenosine Deaminase; Animals; Binding, Competitive; Brain; Cell Line; Choroid Plexus; Corpus Striatum; GTP-Binding Proteins; Hippocampus; Humans; Inosine; Mice; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Serotonin; Signal Transduction; Transfection; Tumor Cells, Cultured | 1997 |
Effect of diltiazem on plasma concentrations of oxypurines and uric acid.
Topics: Adenosine; Adult; Cardiovascular Agents; Diltiazem; Female; Guanosine; Humans; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Purines; Uric Acid; Xanthine; Xanthines | 1997 |
Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Female; Inosine; Melarsoprol; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei | 1997 |
Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development.
Topics: Adenosine; Adenosine Deaminase; Animals; Decidua; Deoxyadenosines; Embryonic Development; Female; Inosine; Mice; Mice, Transgenic; Pregnancy; Trophoblasts; Zygote | 1997 |
Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Glucose; Hypoxanthine; Inosine; Iodoacetates; Iodoacetic Acid; Ischemia; Kinetics; Oligomycins; Oxidative Stress; Retina; Thioinosine | 1997 |
The crystal structure of an RNA oligomer incorporating tandem adenosine-inosine mismatches.
Topics: Adenosine; Base Composition; Base Sequence; Binding Sites; Calcium; Crystallization; Crystallography, X-Ray; Hydrogen Bonding; Inosine; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligoribonucleotides; RNA; Water | 1997 |
Relationship between urinary excretion of modified nucleosides and rheumatoid arthritis process.
Topics: Adenosine; Aged; Arthritis, Rheumatoid; Biomarkers; Cytidine; Female; Follow-Up Studies; Guanosine; Humans; Inosine; Male; Middle Aged; Nucleosides; Pseudouridine; RNA Caps; RNA, Ribosomal; RNA, Transfer | 1997 |
Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation.
Topics: Adenine; Adenosine; Animals; Arterioles; Binding, Competitive; Cell Degranulation; Cricetinae; Guinea Pigs; Inosine; Iodine Radioisotopes; Iodobenzenes; Lung; Mast Cells; Norbornanes; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured | 1997 |
Na(+)-dependent purine nucleoside transporter from human kidney: cloning and functional characterization.
Topics: Adenosine; Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 15; Cloning, Molecular; Cricetinae; Deoxyadenosines; Humans; Hybrid Cells; Inosine; Kidney; Membrane Transport Proteins; Molecular Sequence Data; Oocytes; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Uridine; Xenopus laevis | 1997 |
Ischemia induces significant changes in purine nucleoside concentration in the retina-choroid in rats.
Topics: Adenosine; Animals; Choroid; Chromatography, High Pressure Liquid; Hypoxanthine; Inosine; Ischemia; Purine Nucleosides; Rats; Rats, Sprague-Dawley; Regression Analysis; Retina; Retinal Artery Occlusion; Time Factors; Vitreous Body; Xanthine | 1997 |
Molecular cloning and expression of a purine-specific N-ribohydrolase from Trypanosoma brucei brucei. Sequence, expression, and molecular analysis.
Topics: Adenosine; Adenosine Monophosphate; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Hypoxanthine; Inosine; Inosine Monophosphate; Kinetics; Molecular Sequence Data; Molecular Weight; N-Glycosyl Hydrolases; Restriction Mapping; Sequence Alignment; Trypanosoma brucei brucei | 1998 |
Binding of daunomycin to diaminopurine- and/or inosine-substituted DNA.
Topics: Adenosine; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Circular Dichroism; Daunorubicin; Deoxyribonuclease I; DNA; DNA Footprinting; Guanosine; Hexosamines; Inosine; Molecular Sequence Data; Polymerase Chain Reaction; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thermodynamics | 1998 |
Double-stranded RNA poses puzzle.
Topics: Adenosine; Adenosine Deaminase; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calmodulin-Binding Proteins; Gene Expression Regulation; Helminth Proteins; Humans; Inosine; Muscle Proteins; RNA-Binding Proteins; RNA, Complementary; RNA, Double-Stranded; RNA, Helminth | 1998 |
Activation of pulmonary C fibres by adenosine in anaesthetized rats: role of adenosine A1 receptors.
Topics: Action Potentials; Adenosine; Afferent Pathways; Anesthesia, General; Animals; Capsaicin; Inosine; Lung; Male; Nerve Fibers; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Purinergic P1; Respiration; Theobromine; Time Factors; Trachea; Vagus Nerve; Xanthines | 1998 |
The levels of adenosine and its metabolites in the guinea pig and rat brain during complete ischemia-in vivo study.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Ischemia; Chromatography, High Pressure Liquid; Dyneins; Enzyme Inhibitors; Guinea Pigs; Hypoxanthine; Inosine; Male; Microwaves; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Tissue Fixation | 1998 |
The effects of simulated ischemia on the levels of adenosine and its metabolites in slices of cerebellum, superior colliculus and hippocampus in the guinea pig-in vitro study.
Topics: Adenosine; Animals; Brain Chemistry; Brain Ischemia; Cerebellum; Guinea Pigs; Hippocampus; Hypoxanthine; In Vitro Techniques; Inosine; Male; Microwaves; Superior Colliculi | 1998 |
Interstitial adenosine, inosine, and hypoxanthine are increased after experimental traumatic brain injury in the rat.
Topics: Adenosine; Animals; Brain Injuries; Chromatography, High Pressure Liquid; Cyclic AMP; Hypoxanthine; Inosine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet | 1998 |
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Hypoxanthine; Inosine; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Tubercidin | 1998 |
Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties.
Topics: Adenosine; Adenosine Deaminase; Animals; Antihypertensive Agents; Blood Pressure; Inflammation; Inosine; Methyldopa; Molecular Structure; Purine Nucleosides; Rabbits; Rats; Rats, Inbred SHR; Skin | 1998 |
Characterization of a nucleoside/proton symporter in procyclic Trypanosoma brucei brucei.
Topics: Adenosine; Adenosine Triphosphate; Amiloride; Animals; Binding, Competitive; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carrier Proteins; Dicyclohexylcarbodiimide; Fluorescent Dyes; Gramicidin; Hydrogen-Ion Concentration; Inosine; Kinetics; Membrane Potentials; Nigericin; Protozoan Proteins; Purine Nucleosides; Trypanosoma brucei brucei; Tubercidin | 1998 |
Carnitines increase plasma levels of adenosine and ATP in humans.
Topics: Acetylcarnitine; Adenosine; Adenosine Triphosphate; Aged; Analysis of Variance; Cardiotonic Agents; Carnitine; Female; Humans; Infusions, Intravenous; Inosine; Intermittent Claudication; Male | 1997 |
Extending the cleavage rules for the hammerhead ribozyme: mutating adenosine15.1 to inosine15.1 changes the cleavage site specificity from N16.2U16.1H17 to N16.2C16.1H17.
Topics: Adenosine; Base Composition; Base Sequence; Inosine; Molecular Sequence Data; Mutation; RNA, Catalytic; Substrate Specificity | 1998 |
Compensation of endothelin-1-induced coronary vasoconstriction.
Topics: Adenosine; Anesthesia, General; Animals; Coronary Circulation; Dogs; Endothelin-1; Glyburide; Hypoglycemic Agents; Inosine; Potassium Channel Blockers; Vasoconstriction | 1998 |
The effects of nucleotide pool on purine production in the postischemic heart.
Topics: Adenosine; Adenosine Triphosphate; Animals; Hypoxanthine; Inosine; Kinetics; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Purine Nucleotides; Purines; Rats; Time Factors; Uric Acid; Xanthine | 1998 |
Myocardial ischemic injury during cardio-pulmonary by-pass. Evaluation of purine compounds by capillary electrophoresis.
Topics: Adenosine; Aged; Biopsy; Cardiomyopathies; Cardiopulmonary Bypass; Electrophoresis, Capillary; Heart Ventricles; Humans; Hypoxanthine; Inosine; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Purine Nucleotides; Purines | 1998 |
Different mechanism of myocardial nucleotide breakdown during normothermic and hypothermic ischemia.
Topics: Adenosine; Animals; Heart Arrest, Induced; Hypoxanthine; In Vitro Techniques; Inosine; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nucleotides; Rats; Temperature; Time Factors; Uric Acid; Xanthine | 1998 |
[Search for microorganisms among collectable bacterial strains capable of transforming nucleosides into virazole].
Topics: Adenosine; Antiviral Agents; Bacteria; Chromatography, Thin Layer; Culture Media; Guanosine; Hydrolysis; Inosine; Purine-Nucleoside Phosphorylase; Ribavirin; Ribose; Solutions; Spectrophotometry, Ultraviolet | 1998 |
Adenosine stimulates canine retinal microvascular endothelial cell migration and tube formation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Division; Cell Line; Cell Movement; Cells, Cultured; Dogs; Endothelial Growth Factors; Endothelium, Vascular; Inosine; Lymphokines; Neovascularization, Physiologic; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Retinal Vessels; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 1998 |
Adenosine, inosine, and guanosine protect glial cells during glucose deprivation and mitochondrial inhibition: correlation between protection and ATP preservation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Amobarbital; Anaerobiosis; Animals; Astrocytes; Cell Hypoxia; Cell Survival; Coformycin; Dose-Response Relationship, Drug; Electron Transport; Enzyme Inhibitors; GABA Modulators; Glioma; Glucose; Glycolysis; Guanine Nucleotides; Guanosine; Hybrid Cells; Inosine; Inosine Monophosphate; Ischemia; Lactic Acid; Mitochondria; Neuroprotective Agents; Oligodendroglia; Pentosyltransferases; Purine Nucleosides; Rats | 1998 |
Myocardial preconditioning produced by ischemia, hypoxia, and a KATP channel opener: effects on interstitial adenosine in dogs.
Topics: Adenine Nucleotides; Adenosine; Animals; Benzopyrans; Dihydropyridines; Dogs; Extracellular Space; Hemodynamics; Hypoxanthine; Hypoxia; Inosine; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Ischemia; Potassium Channels; Uric Acid; Xanthine | 1998 |
Interstitial ATP level and degradation in control and postmyocardial infarcted rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Heart; Hypoxanthine; In Vitro Techniques; Inosine; Intracellular Fluid; Male; Microdialysis; Myocardial Contraction; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Time Factors; Xanthine | 1998 |
Apoptosis induced by modified ribonucleosides in human cell culture systems.
Topics: Adenosine; Apoptosis; Cells, Cultured; Colonic Neoplasms; Guanosine; HL-60 Cells; Humans; Inosine; Isopentenyladenosine; Kinetics; Lymphocytes; Ribonucleosides; Tumor Cells, Cultured | 1998 |
Axon outgrowth is regulated by an intracellular purine-sensitive mechanism in retinal ganglion cells.
Topics: Adenosine; Animals; Axons; Calcium-Calmodulin-Dependent Protein Kinases; Goldfish; Hydrolysis; Inosine; Phosphatidylinositol 3-Kinases; Purine Nucleosides; Purine Nucleotides; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Thioguanine | 1998 |
Role of the gerI operon of Bacillus cereus 569 in the response of spores to germinants.
Topics: Adenosine; Alanine; Amino Acid Sequence; Bacillus cereus; Base Sequence; Cloning, Molecular; DNA, Bacterial; Genes, Bacterial; Guanosine; Inosine; Molecular Sequence Data; Operon; Sequence Analysis, DNA; Spores, Bacterial | 1998 |
Evidence for an endogenous cAMP-adenosine pathway in the rat kidney.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; Adenosine; Adrenergic beta-Agonists; Animals; Cyclic AMP; Hypoxanthine; Inosine; Isoproterenol; Kidney; Male; Perfusion; Phosphodiesterase Inhibitors; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1998 |
Extracellular adenosine levels and cellular energy metabolism in ischemically preconditioned rat heart.
Topics: 5'-Nucleotidase; Adenosine; Animals; Chromatography, High Pressure Liquid; Energy Metabolism; Extracellular Space; Inosine; Ischemic Preconditioning, Myocardial; Magnetic Resonance Spectroscopy; Male; Microdialysis; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley | 1998 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity.
Topics: 3T3 Cells; Adenosine; Animals; Binding, Competitive; Brain Chemistry; Humans; Inosine; Isomerism; Mice; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; RNA Editing | 1999 |
Effect of aging on myocardial adenosine production, adenosine uptake and adenosine kinase activity in rats.
Topics: Adenosine; Adenosine Kinase; Aging; Animals; Carbon Radioisotopes; Heart; Inosine; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Thioinosine | 1999 |
Role of endogenous adenosine in the expression of opiate withdrawal in rats.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Hypoxanthine; Inosine; Male; Microdialysis; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 1999 |
TIT for TAT: the properties of inosine and adenosine in TATA box DNA.
Topics: Adenosine; Algorithms; Computer Simulation; DNA; Hydrogen Bonding; Hypoxanthine; Inosine; Kinetics; Models, Chemical; Models, Molecular; TATA Box; Thymine | 1999 |
Long RNA hairpins that contain inosine are present in Caenorhabditis elegans poly(A)+ RNA.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; Base Sequence; Caenorhabditis elegans; Guanosine; Inosine; Molecular Sequence Data; Nucleic Acid Conformation; Reverse Transcriptase Polymerase Chain Reaction; RNA Editing; RNA, Helminth; RNA, Messenger | 1999 |
Metabolism of adenosine increase in the striatum in common marmoset parkinsonism induced by MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine; Animals; Callithrix; Corpus Striatum; Extracellular Space; Inosine; Microdialysis; Parkinson Disease, Secondary | 1999 |
Amplification of the cyclic AMP response to forskolin in pheochromocytoma PC12 cells through adenosine A(2A) purinoceptors.
Topics: Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Inosine; Kinetics; PC12 Cells; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sulfonamides; Theophylline | 1999 |
Contributions of adenosine receptor activation to the ocular actions of epinephrine.
Topics: Adenosine; Adrenergic Agonists; Animals; Aqueous Humor; Epinephrine; Inosine; Intraocular Pressure; Ophthalmic Solutions; Pupil; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Theobromine; Theophylline | 1999 |
Catabolism of the methyl derivatives of adenosine and cytidine in staphylococci.
Topics: Adenosine; Cytidine; Inosine; Staphylococcus; Staphylococcus aureus; Uridine | 1999 |
Nucleoside phosphorylation: a feasible step in the prebiotic pathway to RNA.
Topics: Adenosine; Cations, Divalent; Chromatography; Cytidine; Hydrolysis; Inosine; Minerals; Nucleosides; Organophosphorus Compounds; Phosphates; Phosphorylation; Quaternary Ammonium Compounds; RNA; Urea; Uridine | 1999 |
Cardiac endothelial transport and metabolism of adenosine and inosine.
Topics: Adenosine; Animals; Biological Transport; Coronary Vessels; Endothelium, Vascular; Guinea Pigs; Inosine; Myocardial Reperfusion; Myocardium; Rabbits; Species Specificity | 1999 |
Enhanced accumulation of pericardial fluid adenosine and inosine in patients with coronary artery disease.
Topics: Adenosine; Aged; Chromatography, High Pressure Liquid; Coronary Disease; Female; Heart Valve Diseases; Humans; Inosine; Male; Middle Aged; Pericardial Effusion | 1999 |
A halothane test to detect turkeys prone to developing pale, soft, and exudative meat.
Topics: Adenosine; Animals; Color; Food Technology; Halothane; Hydrogen-Ion Concentration; Inosine; Male; Malignant Hyperthermia; Muscle, Skeletal; Poultry; Quality Control; Rigor Mortis; Swine; Turkeys | 1999 |
Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cells.
Topics: Adenosine; Animals; Capillary Permeability; Inosine; Mast Cells; Mice; Mice, Knockout; Receptor, Adenosine A3; Receptors, IgE; Receptors, Purinergic P1; Signal Transduction; Skin; Vasodilator Agents | 2000 |
Serum glucose and insulin response in rats administered with sucrose or starch containing adenosine, inosine or cytosine.
Topics: Adenosine; Animals; Blood Glucose; Cytosine; Enzyme Inhibitors; Enzymes; Gastric Emptying; Inosine; Insulin; Intestines; Male; Rats; Rats, Sprague-Dawley; Starch; Sucrose | 2000 |
Differential regulation of nucleoside and nucleobase transporters in Crithidia fasciculata and Trypanosoma brucei brucei.
Topics: Adenosine; Animals; Carrier Proteins; Crithidia fasciculata; Culture Media; Cycloheximide; Dose-Response Relationship, Drug; Guanosine; Hypoxanthine; Inosine; Membrane Proteins; Nucleoside Transport Proteins; Purine Nucleosides; Purines; Pyrimidine Nucleosides; Trypanosoma brucei brucei; Uracil | 2000 |
A simple high-performance liquid chromatography assay for simultaneous measurement of adenosine, guanosine, and the oxypurine metabolites in plasma.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Guanosine; Humans; Hypoxanthine; Inosine; Purines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Uric Acid; Xanthine | 2000 |
Activation of adenosine A2 alpha receptors inhibits mast cell degranulation and mast cell-dependent vasoconstriction.
Topics: Adenosine; Animals; Cricetinae; Histamine Release; Inosine; Mast Cells; Mesocricetus; Microcirculation; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasodilator Agents | 2000 |
Adenosine and its receptor agonists regulate nitric oxide production and RAW 264.7 macrophages via both receptor binding and its downstream metabolites-inosine.
Topics: Adenine; Adenosine; Bacterial Toxins; Cell Line; Dose-Response Relationship, Drug; Dyneins; Enterotoxins; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Humans; Hypoxanthine; Inosine; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Agonists | 2000 |
Adenosine blocks hormone-induced meiotic maturation by suppressing purine de novo synthesis.
Topics: Adenosine; Animals; Female; Follicle Stimulating Hormone; Inosine; Meiosis; Mice; Mice, Inbred C57BL; Nucleosides; Oocytes; Purines | 2000 |
Further characterization of an adenosine transport system in the mitochondrial fraction of rat testis.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzodiazepinones; Biological Transport; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Guanosine; Hexobendine; Hydrogen-Ion Concentration; Inosine; Isoquinolines; Kinetics; Male; Mitochondria; Osmolar Concentration; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Sodium; Subcellular Fractions; Temperature; Testis; Thioinosine; Thionucleosides; Time Factors; Tritium; Uridine | 2000 |
Blood glucose and insulin concentrations are reduced in humans administered sucrose with inosine or adenosine.
Topics: Adenosine; Adult; Blood Glucose; Drug Evaluation; Enzyme Inhibitors; Female; Humans; Inosine; Insulin; Male; Sucrase; Sucrose; Sweetening Agents | 2000 |
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Convulsants; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Guanosine; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Xanthine | 2000 |
Purine uptake and release in rat C6 glioma cells: nucleoside transport and purine metabolism under ATP-depleting conditions.
Topics: Adenine; Adenosine; Adenosine Triphosphate; AMP Deaminase; Animals; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Equilibrative Nucleoside Transport Proteins; Equilibrative-Nucleoside Transporter 2; Formycins; Glioma; Hypoxanthine; Inosine; Iodoacetates; Nucleosides; Phosphodiesterase Inhibitors; Purines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Sodium; Sodium Cyanide; Thioinosine; Tumor Cells, Cultured | 2000 |
Cardiac fibroblasts express the cAMP-adenosine pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Monophosphate; Analysis of Variance; Animals; Cell Division; Cells, Cultured; Cyclic AMP; Extracellular Space; Fibroblasts; Inosine; Male; Myocardium; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Xanthines | 2000 |
Local and systemic effects of peritoneal lavage with high concentrations of adenosine in rats.
Topics: Adenosine; Adenosine Monophosphate; Angiotensin II; Animals; Blood Pressure; Cardiovascular Agents; Heart Rate; Hypoxanthine; Inosine; Male; Microdialysis; Peritoneal Lavage; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasoconstrictor Agents; Xanthines | 2000 |
Intrinsic A(1) adenosine receptor activation during ischemia or reperfusion improves recovery in mouse hearts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Creatine; Extracellular Space; Heart Function Tests; Heart Rate; Hypoxanthine; In Vitro Techniques; Inosine; Male; Mice; Mice, Inbred C57BL; Microdialysis; Myocardial Ischemia; Myocardium; Phosphocreatine; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Recovery of Function; Reperfusion; Reperfusion Injury; Xanthines | 2000 |
Relationship between free radicals and adenosine in the mechanism of preconditioning: are they interrelated or independent triggers?
Topics: Adenosine; Animals; Antioxidants; Blood Pressure; Dialysis Solutions; Free Radicals; Glycine; Heart Rate; Hypoxanthine; In Vitro Techniques; Inosine; Ischemic Preconditioning, Myocardial; Male; Microdialysis; Myocardium; Rabbits; Sulfhydryl Compounds | 2000 |
Ischemic-like condition releases norepinephrine and purines from different sources in superfused rat spleen strips.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Hypoxanthine; Inosine; Ischemia; Male; Norepinephrine; Rats; Rats, Wistar; Spleen; Sympathectomy; Sympathetic Nervous System; Sympathomimetics; Tetrodotoxin; Tritium; Vasodilator Agents; Xanthine | 2000 |
Structure-inhibitory profiles of nucleosides for the human intestinal N1 and N2 Na+-nucleoside transporters.
Topics: Adenosine; Carrier Proteins; Humans; In Vitro Techniques; Inosine; Intestinal Mucosa; Intestines; Membrane Transport Proteins; Microvilli; Nucleosides; Structure-Activity Relationship; Thymidine; Uridine | 2000 |
Nucleoside transport inhibition in ischemic myocardium results in enhanced taurine efflux.
Topics: Adenosine; Animals; Biological Transport; Dipyridamole; Hypoxanthine; Inosine; Lactates; Microdialysis; Myocardial Ischemia; Nucleosides; Pyruvic Acid; Swine; Taurine; Vasodilator Agents | 2001 |
Adenosine increases ventilation rate, cardiac performance and haemolymph velocity in the American lobster Homarus americanus.
Topics: Adenosine; Animals; Arteries; Gills; Heart Rate; Hemolymph; Inosine; Nephropidae; Oxygen Consumption | 2001 |
Development. Survival is impossible without an editor.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Pairing; Central Nervous System; Chimera; Drosophila; Embryo, Mammalian; Embryo, Nonmammalian; Erythropoiesis; Gene Dosage; Hematopoietic Stem Cells; Inosine; Liver; Mice; Mutation; Phenotype; Protein Structure, Tertiary; Receptors, AMPA; RNA Editing; RNA Precursors; RNA-Binding Proteins; RNA, Double-Stranded; Stem Cells; Teratoma | 2000 |
Renal interstitial adenosine metabolism during ischemia in dogs.
Topics: Adenine; Adenosine; Animals; Antibiotics, Antineoplastic; Dogs; Extracellular Space; Hypoxanthine; Inosine; Ischemia; Kidney; Tubercidin | 2001 |
Adenosine and hemodialysis in humans.
Topics: Adenosine; Adenosine Deaminase; Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Humans; Hypotension; Infections; Inosine; Male; Middle Aged; Renal Dialysis | 2001 |
Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells.
Topics: Adenosine; Animals; Caffeine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theobromine; Theophylline; Transfection | 2001 |
Antiadrenergic effects of adenosine in pressure overload hypertrophy.
Topics: Adenosine; Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; Caffeine; Calcium; Cardiomegaly; Cells, Cultured; Coronary Circulation; Disease Models, Animal; Echocardiography; In Vitro Techniques; Inosine; Isoproterenol; Male; Myocardial Contraction; Myocardium; Organ Size; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley | 2001 |
Adenosine deaminase activity in rat intestine: assay with a microdialysis technique.
Topics: Adenosine; Adenosine Deaminase; Animals; Dose-Response Relationship, Drug; Inosine; Intestines; Microdialysis; Rats; Rats, Wistar | 1998 |
Blood purine and energy status in rats with colitis.
Topics: Acetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomarkers; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Energy Metabolism; Hemoglobins; Inosine; Male; Peroxidase; Purines; Rats; Rats, Wistar; Time Factors; Uric Acid | 2001 |
Ascorbic acid changes the pattern of purine metabolism during germination of white spruce somatic embryos.
Topics: Adenine; Adenosine; Ascorbic Acid; Germination; Inosine; Picea; Purines; Trees | 2001 |
Adenosine in relation to calcium homeostasis: comparison between gray and white matter ischemia.
Topics: Adenosine; Adenosine Triphosphate; Amino Acids; Animals; Brain; Calcium; Cats; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Homeostasis; Hypoxanthine; Inosine; Male; Microdialysis; Vasospasm, Intracranial | 2001 |
Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Dialysis Solutions; Disease Models, Animal; Energy Metabolism; Extracorporeal Circulation; Guanine; Heart Arrest, Induced; Hypoxanthine; Inosine; Lactic Acid; Microdialysis; Myocardial Infarction; Myocardium; Pyruvic Acid; Reperfusion Injury; Swine; Taurine | 2001 |
Exogenous administration of endogenous compounds: an emerging drug-development strategy in critical care pharmacology.
Topics: Adenosine; Animals; Critical Care; Drug Design; Humans; Inosine; Mice | 2001 |
ADAR1 is involved in the development of microvascular lung injury.
Topics: Adenosine; Adenosine Deaminase; Animals; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; In Situ Hybridization; Inosine; Interferon-gamma; Leukocytes; Lung; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Microcirculation; Pulmonary Circulation; Pulmonary Edema; Respiratory Distress Syndrome; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Up-Regulation | 2001 |
Chronic ethanol enhances adenosine antiadrenergic actions in the isolated rat heart.
Topics: Adenosine; Adenylyl Cyclases; Adrenergic Antagonists; Alcoholism; Animals; Cardiovascular Agents; Central Nervous System Depressants; Drug Synergism; Echocardiography; Ethanol; Heart; In Vitro Techniques; Inosine; Male; Myocardial Contraction; Myocardium; Purines; Rats; Rats, Sprague-Dawley | 2001 |
Methylation of the nucleobases in RNA oligonucleotides mediates duplex-hairpin conversion.
Topics: Adenosine; Base Pairing; Cytidine; Guanosine; Hydrogen Bonding; Inosine; Methylation; Nucleic Acid Conformation; Oligoribonucleotides; RNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thermodynamics; Uridine | 2001 |
Pre-conditioning activates adenosine utilization in a cost-effective way during myocardial ischaemia.
Topics: Adenosine; Animals; Deoxyadenosines; Female; Glycolysis; Inosine; Ischemic Preconditioning, Myocardial; Lactic Acid; Male; Microdialysis; Myocardial Ischemia; Myocardium; Pentose Phosphate Pathway; Swine | 2001 |
Vaccinia virus E3L interferon resistance protein inhibits the interferon-induced adenosine deaminase A-to-I editing activity.
Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Inosine; Interferons; Mutation; RNA Editing; RNA-Binding Proteins; Vaccinia virus; Viral Proteins | 2001 |
5'-Adenosine monophosphate and adenosine metabolism, and adenosine responses in mouse, rat and guinea pig heart.
Topics: Adenosine; Adenosine Monophosphate; Animals; Bradycardia; Calcium; Dose-Response Relationship, Drug; Guinea Pigs; Hemoglobins; Inosine; Mice; Models, Biological; Myocardial Contraction; Myocardium; Perfusion; Phosphorylation; Rats; Species Specificity | 2001 |
RNAi is antagonized by A-->I hyper-editing.
Topics: Adenosine; Adenosine Deaminase; Animals; Drosophila; Electrophoresis, Polyacrylamide Gel; Inosine; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Small Interfering; RNA, Untranslated; Transcription, Genetic | 2001 |
Changes in properties of adenosine transporters in Trypanosoma evansi and modes of selection of resistance to the melaminophenyl arsenical drug, Mel Cy.
Topics: Adenine; Adenosine; Animals; Arsenicals; Biological Transport; Biomarkers; Carrier Proteins; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Inosine; Membrane Transport Proteins; Nucleoside Transport Proteins; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma | 2001 |
The efflux of purine nucleobases and nucleosides from the rat brain.
Topics: Adenosine; Animals; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Carrier Proteins; Deoxyribonucleosides; Extracellular Space; Guanosine; Hypoxanthine; Injections, Intraventricular; Inosine; Purine Nucleosides; Purines; Rats; Rats, Wistar | 2002 |
Coronary metabolic adaptation restricted by endothelin in the dog heart.
Topics: Adaptation, Physiological; Adenosine; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Dogs; Endothelin-1; Glyburide; Inosine; Myocardium; Potassium Channels; Vasoconstriction | 2001 |
Anoxia-induced changes in purine nucleoside metabolism of in vitro aged human fibroblasts.
Topics: Adenosine; Cell Hypoxia; Cell Line; Cellular Senescence; Chromatography, High Pressure Liquid; Fibroblasts; Humans; Inosine; Lung; Time Factors | 2002 |
2-aza-2'-deoxyadenosine: synthesis, base-pairing selectivity, and stacking properties of oligonucleotides.
Topics: Adenosine; Azides; Base Pairing; Base Sequence; Inosine; Nucleic Acid Conformation; Oligonucleotides; Thermodynamics | 2000 |
Mechanisms of apoptosis induced by purine nucleosides in astrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Astrocytes; Carrier Proteins; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanine; Guanosine; Hypoxanthine; Inosine; Male; Purine Nucleosides; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger | 2002 |
"Fleximers". Design and synthesis of a new class of novel shape-modified nucleosides(1).
Topics: Adenosine; Adenosylhomocysteinase; Binding Sites; Catalysis; Chemistry, Organic; Guanosine; Hydrolases; Inosine; Models, Molecular; Molecular Conformation; Molecular Structure; Nucleosides | 2002 |
9-[(Hydroxymethyl)phenyl]adenines: new aryladenine substrates of adenosine deaminase.
Topics: Adenosine; Adenosine Deaminase; Animals; Cattle; Chromatography, Thin Layer; Deamination; Inosine; Intestines; Magnetic Resonance Spectroscopy; Purines; Spectrophotometry, Ultraviolet | 2002 |
Investigating the structural basis of purine specificity in the structures of MS2 coat protein RNA translational operator hairpins.
Topics: 2-Aminopurine; Adenosine; Amino Acid Substitution; Base Sequence; Binding Sites; Capsid; Capsid Proteins; Cytidine; Guanosine; Hydrogen Bonding; Inosine; Models, Molecular; Nucleic Acid Conformation; Protein Binding; Protein Biosynthesis; Purines; RNA-Binding Proteins; RNA-Dependent RNA Polymerase; RNA, Viral | 2002 |
Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Ammonium Chloride; Animals; Aspartic Acid; Calcium Signaling; Cyclic AMP; Dose-Response Relationship, Drug; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoxanthine; In Vitro Techniques; Inosine; Kidney Tubules; Ligands; Male; Phosphorylation; Pyruvic Acid; Rabbits; Signal Transduction | 2002 |
Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site.
Topics: Adenosine; Adenosine Deaminase; Base Sequence; Binding Sites; Cloning, Molecular; Humans; Inosine; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Pichia; Protein Binding; Receptors, AMPA; Recombinant Proteins; RNA Editing; RNA Splicing; RNA-Binding Proteins; RNA, Messenger; Substrate Specificity | 2002 |
Pericardial concentrations of adenosine, inosine and hypoxanthine in an experimental canine model of spastic ischaemia.
Topics: Adenosine; Animals; Coronary Vasospasm; Dogs; Endothelin-1; Hypoxanthine; Inosine; Models, Animal; Myocardial Ischemia; Pericardium; Vasoconstrictor Agents | 2002 |
Synthesis and polymerase incorporation of 5'-amino-2',5'-dideoxy-5'-N-triphosphate nucleotides.
Topics: Adenosine; Base Sequence; Chromatography, High Pressure Liquid; Cytidine; Dideoxynucleosides; DNA; DNA Polymerase I; Guanosine; Inosine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Sequence Analysis, DNA; Thymidine; Uridine | 2002 |
Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Guinea Pigs; Heart; Hyperkalemia; Hypothermia; Hypoxanthine; Inosine; L-Lactate Dehydrogenase; Lactates; Myocardium; Purines; Reperfusion Injury; Temperature; Time Factors; Xanthine | 2002 |
A product inhibition study on adenosine deaminase by spectroscopy and calorimetry.
Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Binding, Competitive; Calorimetry, Differential Scanning; Cattle; Entropy; Hot Temperature; Inosine; Intestinal Mucosa; Kinetics; Spectrophotometry, Ultraviolet; Substrate Specificity; Thermodynamics | 2002 |
Rapid adenosine release in the nucleus tractus solitarii during defence response in rats: real-time measurement in vivo.
Topics: Adenosine; Adenosine Diphosphate; Animals; Biosensing Techniques; Brain Stem; Computer Systems; Electric Stimulation; Enzyme Inhibitors; Escape Reaction; Hypothalamus; Inosine; Microelectrodes; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Time Factors | 2002 |
8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.
Topics: Adenosine; Animals; Aza Compounds; Cattle; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Inosine; N-Glycosyl Hydrolases; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship | 2003 |
Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms.
Topics: Adenosine; Adenosine Monophosphate; Cyclic GMP; Ethylenediamines; Guanosine Monophosphate; Inosine; Inosine Monophosphate; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acids; Nucleosides; Nucleotides; Organometallic Compounds; Ruthenium; Substrate Specificity; Thymidine Monophosphate | 2003 |
Ischemic preconditioning does not improve myocardial preservation during off-pump multivessel coronary operation.
Topics: Adenosine; Coronary Vessels; Creatine Kinase; Creatine Kinase, MB Form; Energy Metabolism; Humans; Hydrogen-Ion Concentration; Inosine; Ischemic Preconditioning; Isoenzymes; Lactates; Middle Aged; Myocardium; Troponin I; Xanthine | 2003 |
Oviduct cells express the cyclic AMP-adenosine pathway.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Cells, Cultured; Coculture Techniques; Cyclic AMP; Enzyme Activators; Enzyme Inhibitors; Epithelial Cells; Extracellular Space; Fallopian Tubes; Female; Fibroblasts; Inosine; Intracellular Fluid | 2003 |
Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.
Topics: Adenosine; Adenosine Diphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Hydroxy Acids; Hypoxanthine; Inosine; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Contraction; Myocardial Infarction; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Phenanthridines; Phenethylamines; Potassium Channels; Protein Kinase C; Receptors, Purinergic P2; Signal Transduction; Xanthine | 2003 |
Intraocular adenosine levels in normal and ocular-hypertensive patients.
Topics: Adenosine; Aqueous Humor; Case-Control Studies; Chromatography, High Pressure Liquid; Humans; Inosine; Intraocular Pressure; Ocular Hypertension; Osmolar Concentration | 2003 |
Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii.
Topics: Adenosine; Animals; Biological Transport; Cells, Cultured; Host-Parasite Interactions; Hypoxanthine; Inosine; Nucleobase Transport Proteins; Nucleoside Transport Proteins; Nucleosides; Purine Nucleosides; Substrate Specificity; Toxoplasma | 2003 |
ADAR2 A-->I editing: site selectivity and editing efficiency are separate events.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Binding Sites; Electrophoretic Mobility Shift Assay; Inosine; Molecular Sequence Data; Nucleic Acid Conformation; Oligoribonucleotides; Rats; Receptors, AMPA; Recombinant Proteins; RNA Editing; RNA Precursors; RNA-Binding Proteins; Substrate Specificity | 2003 |
Nervous system targets of RNA editing identified by comparative genomics.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Drosophila; Drosophila melanogaster; Genes, Insect; Genomics; Humans; Inosine; Ion Channel Gating; Ion Channels; Molecular Sequence Data; Nervous System; Phylogeny; Potassium Channels; Reverse Transcriptase Polymerase Chain Reaction; RNA Editing; RNA-Binding Proteins; Synapses; Synaptic Transmission | 2003 |
Validity of the microdialysis technique for experimental in vivo studies of myocardial energy metabolism.
Topics: Adenosine; Animals; Biopsy; Energy Metabolism; Hypoxanthine; Inosine; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Reproducibility of Results; Swine | 2003 |
High-resolution real-time recording with microelectrode biosensors reveals novel aspects of adenosine release during hypoxia in rat hippocampal slices.
Topics: Adenosine; Animals; Biosensing Techniques; Cell Hypoxia; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Inosine; Male; Microelectrodes; Neural Inhibition; Purines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Purinergic P1; Reproducibility of Results; Synaptic Transmission | 2003 |
Carbocyclic analogues of nucleosides from bis-(Hydroxymethyl)-cyclopentane: synthesis, antiviral and cytostatic activities of adenosine, inosine and uridine analogues.
Topics: Adenosine; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Chromatography, Thin Layer; Cyclopentanes; DNA Viruses; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Inosine; Magnetic Resonance Spectroscopy; Mice; RNA Viruses; Spectroscopy, Fourier Transform Infrared; Uridine | 2003 |
Intracellular localization of differentially regulated RNA-specific adenosine deaminase isoforms in inflammation.
Topics: Adenosine; Adenosine Deaminase; Alternative Splicing; Animals; Base Sequence; Blotting, Western; Cell Nucleolus; Cell Nucleus; Cloning, Molecular; Cytoplasm; Exons; Green Fluorescent Proteins; HeLa Cells; Humans; Immunohistochemistry; Inflammation; Inosine; Luminescent Proteins; Male; Methionine; Mice; Mice, Inbred C57BL; Microscopy, Electron; Microscopy, Fluorescence; Models, Genetic; Molecular Sequence Data; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA-Binding Proteins; Sequence Homology, Nucleic Acid; Spleen; Transfection; Up-Regulation | 2003 |
Formation of adenosine by cell-free extracts of Escherichia coli.
Topics: Adenine; Adenosine; Biochemical Phenomena; Escherichia coli; Inosine | 1954 |
Effects of purine nucleosides on the in vitro growth of Cryptosporidium parvum.
Topics: Adenosine; Animals; Cattle; Cell Line; Chromatography, High Pressure Liquid; Cryptosporidium parvum; Culture Media; Formycins; Humans; Hypoxanthine; Inosine; Purine Nucleosides | 2003 |
Phosphate-transfer reactions of adenosine and inosine nucleotides.
Topics: Adenosine; Inosine; Inosine Nucleotides; Nucleotides; Phosphates | 1955 |
Enzymatic synthesis of adenosine-5'-phosphate from inosine-5'-phosphate.
Topics: Adenosine; Adenosine Monophosphate; Enzymes; Escherichia coli; Inosine; Nucleotides; Phosphates | 1956 |
Rephosphorylation produced by inosine and adenosine of adenosine monophosphate and adenosine diphosphate in human erythrocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Erythrocytes; Humans; Inosine; Nucleotides | 1957 |
Enzymic transfer of the ribosyl group from inosine to adenine.
Topics: Adenine; Adenosine; Humans; Inosine; Xanthines | 1957 |
Histamine release and pain production by xanthosine and related compounds.
Topics: Adenosine; Animals; Cats; Female; Guanosine; Guinea Pigs; Histamine; Histamine Release; Humans; Ileum; Injections, Intradermal; Inosine; Male; Nucleosides; Nucleotides; Pain; Ribonucleosides; Xanthine; Xanthines | 1957 |
Studies on the preservation of blood. VI. The influence of adenosine and inosine on the metabolism of the erythrocyte.
Topics: Adenosine; Blood Preservation; Erythrocytes; Humans; Inosine; Leadership; Nucleosides; Nucleotides; Preservation, Biological | 1958 |
Effects of ionizing radiation on aqueous solutions of inosine and adenosine.
Topics: Adenosine; Inosine; Nucleosides; Nucleotides; Radiation Effects; Radiation, Ionizing | 1960 |
[Dephosphorylation and deamination of adenosine and inosine derivatives of glucose amination in the bone marrow].
Topics: Adenosine; Amination; Biochemical Phenomena; Bone Marrow; Deamination; Glucose; Humans; Inosine; Nucleosides; Nucleotides | 1959 |
Separation of adenine, hypoxanthine, and the 5'-(mono-,di-,and tri-)-phosphates of adenosine and inosine by one-dimensional paper chromatography.
Topics: Adenine; Adenine Nucleotides; Adenosine; Chromatography; Chromatography, Paper; Hypoxanthine; Inosine; Nucleosides; Nucleotides; Phosphates; Retinal Degeneration; Retinal Detachment | 1962 |
Phosphorylated carbohydrate intermediates of the human erythrocyte during storage in acid citrate dextrose. III. Effect of incubation at 37 degrees C. with inosine, inosine plus adenine, and adenosine after storage for 6, 10, 14 and 18 weeks.
Topics: Adenine; Adenosine; Blood Preservation; Carbohydrates; Citrates; Citric Acid; Cold Temperature; Erythrocytes; Glucose; Humans; Inosine; Nucleosides; Nucleotides | 1962 |
[ACTION OF ADENOSINE-5- MONOPHOSPHORIC ACID AND OF INOSINE ON PORPHYRIN METABOLIMS IN EXPERIMENTAL SATURNISM].
Topics: Adenine Nucleotides; Adenosine; Animals; Inosine; Lagomorpha; Lead Poisoning; Metabolism; Nucleosides; Pharmacology; Porphyrins; Rabbits; Research | 1963 |
THE INFLUENCE OF ADENOSINE, INOSINE AND ADENINE ON THE ELECTROPHORETIC PATTERNS OF RED CELL HEMOLYSATES OF STORED BLOOD.
Topics: Adenine; Adenosine; Blood Preservation; Electrophoresis; Erythrocytes; Humans; Inosine; Nucleosides; Protein Hydrolysates; Research | 1964 |
REGULATION OF XANTHINE DEHYDROGENASE IN CHICK LIVER. EFFECT OF STARVATION AND OF ADMINISTRATION OF PURINES AND PURINE NUCLEOSIDES.
Topics: Adenine; Adenosine; Animals; Chickens; Cortisone; Guanine; Guanosine; Hypoxanthines; Inosine; Liver; Nucleosides; Pharmacology; Poultry; Purine Nucleosides; Purines; Puromycin; Research; Ribonucleosides; Spectrophotometry; Starvation; Xanthine Dehydrogenase; Xanthine Oxidase; Xanthines | 1965 |
[Paper chromatography of various phosphates and in particular phosphorylated derivatives of adenosine].
Topics: Adenosine; Adenosine Triphosphate; Chromatography; Chromatography, Paper; Inosine; Nucleotides; Phosphates; Phosphorylation | 1954 |
[Cardiovascular effects of adenylic acid derivaties; adenine, inosine, adenosine, A5MP and of a related compound, cytidine].
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Cardiovascular System; Cytidine; Inosine; Nucleosides; Nucleotides | 1961 |
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
Topics: Adenine; Adenosine; Animals; Arsenicals; Benzamidines; Cell Death; Cell Division; Diminazene; Drug Resistance; Female; Gene Silencing; Hypoxanthine; Inhibitory Concentration 50; Inosine; Melarsoprol; Mice; Mutation; Nucleoside Transport Proteins; Pentamidine; Stilbamidines; Trypanosoma brucei brucei | 2003 |
Aging-related changes in myocardial purine metabolism and ischemic tolerance.
Topics: Adenosine; Aging; Animals; Female; Hypoxanthine; Inosine; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Organ Culture Techniques; Purines | 2003 |
Effects of base substitutions in an RNA hairpin from molecular dynamics and free energy simulations.
Topics: Adenosine; Carbohydrates; Computer Simulation; Hydrogen Bonding; Inosine; Ions; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Nucleic Acid Conformation; Protein Structure, Tertiary; RNA; Sodium; Temperature; Thermodynamics; Time Factors; Water | 2003 |
Comparison of the effect of water release on the interaction of the Saccharomyces cerevisiae TATA binding protein (TBP) with "TATA Box" sequences composed of adenosine or inosine.
Topics: Adenosine; Base Sequence; Binding Sites; Fluorescence Resonance Energy Transfer; Inosine; Molecular Sequence Data; Protein Binding; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; TATA Box; TATA Box Binding Protein-Like Proteins; TATA-Box Binding Protein; Water | 2004 |
Changes in adenosine transport associated with melaminophenyl arsenical (Mel CY) resistance in Trypanosoma evansi: down-regulation and affinity changes of the P2 transporter.
Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Down-Regulation; Drug Resistance; Inosine; Kinetics; Nucleoside Transport Proteins; Trypanocidal Agents; Trypanosoma | 2003 |
RNA editing and alternative splicing of human serotonin 2C receptor in schizophrenia.
Topics: Adenosine; Aged; Alternative Splicing; Case-Control Studies; Female; Humans; Inosine; Male; Prefrontal Cortex; Protein Isoforms; Receptor, Serotonin, 5-HT2C; Reverse Transcriptase Polymerase Chain Reaction; RNA Editing; RNA, Messenger; Schizophrenia | 2003 |
Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.
Topics: Adenosine; Amino Acid Substitution; Biological Transport; Dilazep; Dipyridamole; Drug Resistance; Equilibrative Nucleoside Transporter 1; Guanosine; Humans; Inhibitory Concentration 50; Inosine; Leucine; Mutagenesis; Mutation, Missense; Point Mutation; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Thioinosine | 2004 |
Methods for the analysis of adenosine-to-inosine editing in RNA.
Topics: Adenosine; Adenosine Deaminase; Chromatography, Thin Layer; Humans; Hydrolysis; Inosine; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA Editing; RNA Precursors; RNA, Messenger | 2004 |
Stimulus- and cell-type-specific release of purines in cultured rat forebrain astrocytes and neurons.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Astrocytes; Cell Hypoxia; Cells, Cultured; Deoxyglucose; Glucose; Inosine; Iodoacetic Acid; Neurons; Oligomycins; Prosencephalon; Purines; Rats; Stimulation, Chemical | 2004 |
Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia.
Topics: Adenosine; Animals; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebellum; Guanosine; Inosine; Neurites; Neuroprotective Agents; Purine Nucleosides; Rats; Rats, Sprague-Dawley; Rotenone; Time Factors; Uncoupling Agents | 2004 |
Systematic identification of abundant A-to-I editing sites in the human transcriptome.
Topics: Adenosine; Base Pair Mismatch; Base Pairing; Base Sequence; Chromosome Mapping; Expressed Sequence Tags; Humans; Inosine; Molecular Sequence Data; RNA Editing; Sequence Alignment; Sequence Analysis, DNA; Sequence Analysis, RNA; Sequence Homology, Nucleic Acid; Transcription Factors | 2004 |
Editing the message from A to I.
Topics: Adenosine; Base Pair Mismatch; Base Pairing; Base Sequence; Chromosome Mapping; Expressed Sequence Tags; Humans; Inosine; Molecular Sequence Data; RNA Editing; Sequence Alignment; Sequence Analysis, DNA; Sequence Analysis, RNA; Sequence Homology, Nucleic Acid; Transcription Factors | 2004 |
A direct, efficient method for the preparation of n6-protected 15n-labeled adenosines.
Topics: Adenosine; Amides; Catalysis; Indicators and Reagents; Inosine; Nitrogen Isotopes; Palladium | 2004 |
Metabolic regulation of ATP breakdown and of adenosine production in rat brain extracts.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Guanosine; Guanosine Triphosphate; Hypoxanthine; Inosine; Inosine Monophosphate; Rats | 2004 |
Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.
Topics: Adenosine; Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Biomarkers; Brain; Convulsants; Disease Models, Animal; Female; Guanosine; Guanosine Diphosphate; Hydrolysis; Inosine; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Pentylenetetrazole; Phosphopyruvate Hydratase; Purines; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Seizures; Time Factors; Up-Regulation | 2004 |
Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome.
Topics: 5' Untranslated Regions; Adenosine; Adenosine Deaminase; Alternative Splicing; Alu Elements; Animals; Base Pair Mismatch; Brain; Caenorhabditis elegans; Computational Biology; Conserved Sequence; Databases, Genetic; DNA, Complementary; Exons; Expressed Sequence Tags; Genome; Genome, Human; Humans; Inosine; Introns; Models, Genetic; Models, Statistical; Molecular Sequence Data; Proteome; Receptors, G-Protein-Coupled; RNA; RNA Editing; RNA Processing, Post-Transcriptional; RNA, Messenger; Software | 2004 |
Is abundant A-to-I RNA editing primate-specific?
Topics: 3' Untranslated Regions; Adenosine; Alu Elements; Animals; Chickens; Computational Biology; Drosophila; Genome; Genome, Human; Humans; Inosine; Primates; Rats; RNA Editing; RNA, Double-Stranded; RNA, Messenger | 2005 |
Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing.
Topics: Adenosine; Adenosine Deaminase; Alternative Splicing; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; Brain; Cloning, Molecular; DNA, Complementary; Embryo, Mammalian; Enhancer Elements, Genetic; Exons; Fibroblasts; Inosine; Interferons; Mice; Mice, Inbred BALB C; Models, Genetic; Molecular Sequence Data; Physical Chromosome Mapping; Plasmids; Promoter Regions, Genetic; Protein Isoforms; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA-Binding Proteins; RNA, Messenger; Salmonella; Sequence Homology, Nucleic Acid; Time Factors; Tissue Distribution | 2005 |
Identification and characterization of purine nucleoside transporters from Crithidia fasciculata.
Topics: Adenosine; Amino Acid Sequence; Animals; Cloning, Molecular; Crithidia fasciculata; Culture Media; Genome, Protozoan; Guanosine; Hypoxanthine; Inosine; Molecular Sequence Data; Nucleoside Transport Proteins; Open Reading Frames; Protozoan Proteins; Purine Nucleosides; Sequence Alignment; Xanthine | 2005 |
Evolutionarily conserved human targets of adenosine to inosine RNA editing.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Substitution; Animals; Chickens; Contractile Proteins; Evolution, Molecular; Filamins; Genomics; Humans; Inosine; Insulin-Like Growth Factor Binding Proteins; Mice; Microfilament Proteins; Models, Molecular; Molecular Sequence Data; Neoplasm Proteins; RNA Editing; RNA-Binding Proteins; RNA, Messenger | 2005 |
Activation of glutamate receptors promotes a calcium-dependent and transporter-mediated release of purines in cultured avian retinal cells: possible involvement of calcium/calmodulin-dependent protein kinase II.
Topics: Adenosine; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Glutamic Acid; Hypoxanthine; Inosine; Neurons; Nucleoside Transport Proteins; Presynaptic Terminals; Purines; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina; Synaptic Transmission | 2005 |
Molecular determinants and guided evolution of species-specific RNA editing.
Topics: Adenosine; Amino Acid Sequence; Animals; Base Sequence; Calcium-Binding Proteins; Evolution, Molecular; Exons; Genomics; Inosine; Introns; Membrane Glycoproteins; Models, Molecular; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Phylogeny; RNA Editing; RNA Precursors; Species Specificity; Synaptotagmin I; Synaptotagmins; Time Factors | 2005 |
Purification and characterization of RihC, a xanthosine-inosine-uridine-adenosine-preferring hydrolase from Salmonella enterica serovar Typhimurium.
Topics: Adenosine; Hydrogen-Ion Concentration; Inosine; Kinetics; Molecular Weight; N-Glycosyl Hydrolases; Ribonucleosides; Salmonella typhimurium; Substrate Specificity; Uridine; Xanthines | 2005 |
A bioinformatic screen for novel A-I RNA editing sites reveals recoding editing in BC10.
Topics: Adenosine; Algorithms; Animals; Base Sequence; Chromosome Mapping; Humans; Inosine; Mice; Molecular Sequence Data; Neoplasm Proteins; RNA Editing; Sequence Alignment; Sequence Analysis, RNA; Sequence Homology, Nucleic Acid | 2005 |
[Quantitative analysis of the nucleosides in Cordyceps sinensis with capillary zone electrophoresis].
Topics: Adenosine; Animals; Cordyceps; Culture Techniques; Electrophoresis, Capillary; Guanosine; Inosine; Lepidoptera; Uridine | 2005 |
Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
Topics: Adenine; Adenosine; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrons; Formycins; Humans; Hydrolysis; Inhibitory Concentration 50; Inosine; Ligands; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Purine-Nucleoside Phosphorylase; Recombinant Proteins; Substrate Specificity; Threonine; Time Factors; Trichomonas vaginalis; X-Rays | 2005 |
Astrocytes and neurons: different roles in regulating adenosine levels.
Topics: Adenosine; Affinity Labels; Animals; Astrocytes; Brain Ischemia; Cells, Cultured; Deoxyglucose; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Hypoxia; Inosine; Models, Biological; Neurons; Oligomycins; Phosphodiesterase Inhibitors; Prosencephalon; Purines; Rats; Thioinosine; Tritium | 2005 |
Intrapericardial adenine nucleosides induce elevation of endothelin-1 concentration in the pericardial space of the dog heart.
Topics: Adenosine; Animals; Dogs; Endothelin-1; Female; Heart Rate; Inosine; Male; Myocardial Contraction; Myocardium; Pericardium; Up-Regulation; Ventricular Pressure | 2004 |
Cardiovascular responses to catecholamines and interactions with endothelin-1 and adenine nucleosides in the pericardium of the dog heart.
Topics: Adenosine; Animals; Blood Pressure; Dogs; Dopamine; Endothelin-1; Heart Rate; Hemodynamics; Injections, Intravenous; Inosine; Norepinephrine; Pericardium; Up-Regulation; Ventricular Function, Left; Ventricular Pressure | 2004 |
Nitrogen oxide blockade does not aggravate the endothelin-1-induced myocardial ischemia and release of purine metabolites from the dog heart.
Topics: Adaptation, Physiological; Adenosine; Animals; Disease Models, Animal; Dogs; Endothelin-1; Enzyme Inhibitors; Hemodynamics; Hypoxanthine; Inosine; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pericardium; Purines | 2004 |
Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation.
Topics: Adenosine; Animals; Cell Hypoxia; Cell Survival; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Guanosine; Hypoxia, Brain; Inosine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Degeneration; Nerve Growth Factor; Neuroprotective Agents; PC12 Cells; Purine Nucleosides; Rats; Rotenone; Uncoupling Agents | 2005 |
New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1.
Topics: Adenosine; Cell Line, Tumor; Hepacivirus; Hepatitis C; Humans; Inosine; Interferon-alpha; Replicon; RNA Editing; RNA, Viral; Virus Replication | 2005 |
Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene.
Topics: Adenosine; Animals; Automation; Biological Transport; Cytidine; Databases as Topic; DNA; DNA Primers; Electrodes; Exons; Genetic Variation; Humans; Inosine; Kinetics; Membrane Transport Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Nucleosides; Oocytes; Patch-Clamp Techniques; Plasmids; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protein Structure, Tertiary; Protons; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Analysis, DNA; Sodium; Uridine; Xenopus laevis | 2005 |
Computational study of IAG-nucleoside hydrolase: determination of the preferred ground state conformation and the role of active site residues.
Topics: Adenosine; Animals; Aspartic Acid; Binding Sites; Calcium; Cations, Divalent; Computational Biology; Computer Simulation; Crystallography, X-Ray; Guanosine; Inosine; Models, Molecular; N-Glycosyl Hydrolases; Protein Conformation; Protein Structure, Secondary; Protons; Ribose; Substrate Specificity; Thermodynamics; Trypanosoma vivax | 2005 |
Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma.
Topics: Adenosine; Aged; Aged, 80 and over; Anterior Eye Segment; Aqueous Humor; Blotting, Northern; Cell Culture Techniques; Chromatography, High Pressure Liquid; Exfoliation Syndrome; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Hypoxanthine; Immunohistochemistry; In Situ Hybridization; Inosine; Receptor, Adenosine A3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Xanthine | 2005 |
Extracellular cyclic AMP-adenosine pathway in isolated adipocytes and adipose tissue.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adipocytes; Adipose Tissue; Adrenergic beta-Agonists; Animals; Cyclic AMP; Female; Glycerol; Hypoxanthine; Inosine; Isoproterenol; Lipolysis; Male; Swine; Swine, Miniature | 2005 |
A novel nucleophilic approach to 1-alkyladenosines. A two-step synthesis of [1-15N]adenosine from inosine.
Topics: Adenosine; Inosine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes | 2005 |
A method to find tissue-specific novel sites of selective adenosine deamination.
Topics: Adenosine; Adenosine Deaminase; Animals; Brain; Deamination; Immunoprecipitation; Inosine; Mice; Nuclease Protection Assays; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA Editing; RNA-Binding Proteins | 2005 |
Assay of adenosine deaminase isoforms by HPLC.
Topics: Adenine; Adenosine; Adenosine Deaminase; Benzyl Compounds; Chromatography, High Pressure Liquid; Hypoxanthine; Inosine; Isoenzymes | 2006 |
Inosine released after hypoxia activates hepatic glucose liberation through A3 adenosine receptors.
Topics: Adenosine; Adenosine A3 Receptor Antagonists; Animals; Calcium; Cell Hypoxia; Cyclic AMP; Gluconeogenesis; Glucose; Glycogen Phosphorylase; Glycogenolysis; Hepatocytes; Inosine; Liver; Male; Phylogeny; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptor, Adenosine A3; Receptors, G-Protein-Coupled; Receptors, Purinergic; Receptors, Purinergic P1; Triazoles; Urea | 2006 |
Oxanosine is a substrate of adenosine deaminase. Implications for the quest for a toxicological marker for nitrosation activity.
Topics: Adenosine; Adenosine Deaminase; Biomarkers; Computer Simulation; Deoxyribonucleosides; Inosine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Structure; Nitrosation; Ribonucleosides | 2005 |
Characterization of germination receptors of Bacillus cereus ATCC 14579.
Topics: Adenosine; Amino Acids; Bacillus cereus; Bacterial Proteins; Gene Expression Regulation, Bacterial; Inosine; Mutation; Operon; Receptors, Cell Surface; Ribonucleosides; Spores, Bacterial | 2006 |
Effect of allopurinol on brain adenosine levels during hypoxia in newborn piglets.
Topics: Adenosine; Allopurinol; Animals; Animals, Newborn; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Energy Metabolism; Free Radical Scavengers; Hypoxia; Inosine; Magnetic Resonance Spectroscopy; Models, Statistical; Purines; Swine | 2006 |
Adenosine as an active component of Antrodia cinnamomea that prevents rat PC12 cells from serum deprivation-induced apoptosis through the activation of adenosine A(2A) receptors.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Aminohydrolases; Animals; Apoptosis; Culture Media, Serum-Free; Inosine; PC12 Cells; Polyporales; Rats; Triazines; Triazoles | 2006 |
Extensive adenosine-to-inosine editing detected in Alu repeats of antisense RNAs reveals scarcity of sense-antisense duplex formation.
Topics: Adenosine; Alu Elements; Base Pairing; Humans; Inosine; Introns; RNA Editing; RNA, Antisense; RNA, Double-Stranded; Untranslated Regions | 2006 |
RNA editing of human microRNAs.
Topics: Adenosine; Humans; Inosine; MicroRNAs; RNA Editing; RNA Precursors; RNA, Double-Stranded | 2006 |
An expedient synthesis of N6-substituted-5'-modified adenosines.
Topics: Adenosine; Inosine; Molecular Structure | 2006 |
Gene expression for enzymes and transporters involved in regulating adenosine and inosine levels in rat forebrain neurons, astrocytes and C6 glioma cells.
Topics: Adenosine; Animals; Astrocytes; Cells, Cultured; Cloning, Molecular; Enzymes; Gene Expression; Glioma; Inosine; Mice; Neurons; Nucleotide Transport Proteins; Prosencephalon; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 2006 |
Recognition of intestinal epithelial HIF-1alpha activation by Pseudomonas aeruginosa.
Topics: Adenosine; Caco-2 Cells; Cell Hypoxia; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inosine; Intestinal Mucosa; Plasminogen Activator Inhibitor 1; Pseudomonas aeruginosa; Recombinant Proteins; Transfection | 2007 |
A-to-I pre-mRNA editing of the serotonin 2C receptor: comparisons among inbred mouse strains.
Topics: Adenosine; Animals; Base Sequence; Brain; Cloning, Molecular; Exons; Genetic Variation; Inosine; Introns; Mice; Mice, Inbred Strains; Protein Isoforms; Receptor, Serotonin, 5-HT2C; RNA Editing; RNA Precursors; Species Specificity | 2006 |
Simultaneous determination of adenosine and its metabolites by capillary electrophoresis as a rapid monitoring tool for 5'-nucleotidase activity.
Topics: 5'-Nucleotidase; Adenosine; Cell Line, Tumor; Electrophoresis, Capillary; Humans; Hypoxanthine; Inosine; Reproducibility of Results | 2006 |
Molecular interactions underlying the unusually high adenosine affinity of a novel Trypanosoma brucei nucleoside transporter.
Topics: Adenosine; Animals; Cloning, Molecular; Inosine; Models, Molecular; Nucleoside Transport Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Trypanosoma brucei brucei | 2007 |
High-throughput screening for functional adenosine to inosine RNA editing systems.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Humans; Inosine; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Saccharomyces cerevisiae; Substrate Specificity | 2006 |
The pancreatohepatorenal cAMP-adenosine mechanism.
Topics: Adenosine; Adenosine Monophosphate; Animals; Cyclic AMP; Glucagon; Glucose; Inosine; Kidney; Liver; Male; Microdialysis; Pancreas; Probenecid; Rats | 2007 |
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; Base Sequence; Brain; HeLa Cells; Humans; Inosine; Liver; Mice; MicroRNAs; Molecular Sequence Data; Nucleic Acid Conformation; Organ Specificity; Protein Serine-Threonine Kinases; Ribose-Phosphate Pyrophosphokinase; RNA Editing; RNA Interference; RNA-Binding Proteins; Uric Acid | 2007 |
Nearest neighbor parameters for inosine x uridine pairs in RNA duplexes.
Topics: Adenosine; Algorithms; Base Pairing; Base Sequence; Guanosine; Inosine; Molecular Structure; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; RNA; Thermodynamics; Uridine | 2007 |
Exogenous nucleic acids and nucleotides are efficiently hydrolysed and taken up as nucleosides by intestinal explants from suckling piglets.
Topics: Absorption; Adenosine; Animals; Animals, Suckling; Culture Media; Cytidine; Guanosine; Hydrolysis; Inosine; Jejunum; Nucleosides; Nucleotides; RNA; Swine; Uridine | 2007 |
Uric acid heralds ischemic tissue injury to mobilize endothelial progenitor cells.
Topics: Adenosine; Animals; Cell Movement; Chronic Disease; Endothelial Cells; Hyperuricemia; Inosine; Ischemia; Ischemic Preconditioning; Kidney; Mice; Mice, Inbred Strains; Oxonic Acid; Stem Cells; Urate Oxidase; Uric Acid | 2007 |
RNA binding-independent dimerization of adenosine deaminases acting on RNA and dominant negative effects of nonfunctional subunits on dimer functions.
Topics: Adenosine; Adenosine Deaminase; Catalytic Domain; Dimerization; Humans; Inosine; Point Mutation; Protein Binding; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; Substrate Specificity | 2007 |
Control of basal extracellular adenosine concentration in rat cerebellum.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine Triphosphate; Animals; Biosensing Techniques; Cerebellum; Electric Stimulation; Electrophysiology; Equilibrative Nucleoside Transport Proteins; Excitatory Postsynaptic Potentials; Extracellular Space; Hypoxanthine; In Vitro Techniques; Inosine; Male; Microelectrodes; Neural Inhibition; Nucleobase Transport Proteins; Purine-Nucleoside Phosphorylase; Purkinje Cells; Rats; Rats, Wistar; Receptor, Adenosine A1; Synaptic Transmission; Time Factors | 2007 |
An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Sequence; Base Sequence; Cell Line; Cytidine; Cytidine Deaminase; Deamination; Inosine; Molecular Sequence Data; RNA Editing; RNA Interference; Uridine | 2007 |
Adenosine metabolism and its effect on methylation potential in cultured cells: methodological considerations.
Topics: Adenine Nucleotides; Adenosine; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Line, Tumor; Chelating Agents; Culture Media; Edetic Acid; Humans; Inosine; Kinetics; Liver Neoplasms; Methylation; S-Adenosylmethionine; Time Factors; Trypsin | 2007 |
Hyperphagia-mediated obesity in transgenic mice misexpressing the RNA-editing enzyme ADAR2.
Topics: Adenosine; Adenosine Deaminase; Animals; Caloric Restriction; Cytomegalovirus; Female; Inosine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mutation; Obesity; Promoter Regions, Genetic; Rats; RNA-Binding Proteins | 2007 |
Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Benzyl Compounds; Cyclic Nucleotide Phosphodiesterases, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Hyperthyroidism; Inosine; Male; Myocardial Contraction; Pentostatin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Receptor, Adenosine A1; Signal Transduction; Thyroxine | 2007 |
Comparative genomic and bioinformatic approaches for the identification of new adenosine-to-inosine substrates.
Topics: Adenosine; Animals; Base Sequence; Binding Sites; Computational Biology; Evolution, Molecular; Genetic Techniques; Genomics; Humans; Inosine; Molecular Sequence Data; Primates; RNA Editing; RNA, Messenger; Substrate Specificity | 2007 |
Genetic approaches to studying adenosine-to-inosine RNA editing.
Topics: Adenosine; Adenosine Deaminase; Animals; Cell Line; DNA Primers; DNA Restriction Enzymes; Drosophila; Genetic Techniques; Genomics; Genotype; Inosine; Models, Genetic; Nucleic Acid Conformation; RNA Editing; Saccharomyces cerevisiae | 2007 |
A method for finding sites of selective adenosine deamination.
Topics: Adenosine; Adenosine Deaminase; Animals; Biochemistry; Brain; Genetic Techniques; Humans; Immunoprecipitation; Inosine; Mice; Oligonucleotide Array Sequence Analysis; Protein Binding; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded | 2007 |
Mouse models to elucidate the functional roles of adenosine-to-inosine editing.
Topics: Adenosine; Animals; Base Sequence; Inosine; Ion Channels; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Potassium Channels; Protein Structure, Tertiary; Receptor, Serotonin, 5-HT2C; RNA Editing; Substrate Specificity | 2007 |
Probing adenosine-to-inosine editing reactions using RNA-containing nucleoside analogs.
Topics: Adenosine; Adenosine Deaminase; Base Sequence; Biochemistry; Humans; Inosine; Kinetics; Models, Chemical; Molecular Sequence Data; Oligonucleotides; RNA; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; Saccharomyces cerevisiae | 2007 |
Determination of the impurity profile of adenosine by means of ion-pair reversed-phase chromatography.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Contamination; Europe; Guanosine; Inosine; Pharmaceutical Preparations; Pharmacopoeias as Topic; Quality Control; Quaternary Ammonium Compounds; Reproducibility of Results; Technology, Pharmaceutical; Temperature; Uridine | 2006 |
Identification and relative quantification of adenosine to inosine editing in serotonin 2c receptor mRNA by CE.
Topics: Adenosine; Animals; Base Sequence; Brain; DNA Primers; DNA, Complementary; Electrophoresis, Capillary; Inosine; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; RNA Editing; RNA, Messenger | 2007 |
Changes in serum adenosine deaminase activity during normal pregnancy.
Topics: Adenosine; Adenosine Deaminase; Adult; Analysis of Variance; Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Inosine; Logistic Models; Maternal Age; Pregnancy; Substrate Specificity | 2007 |
Altered adenosine-to-inosine RNA editing in human cancer.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Animals; Base Sequence; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Computational Biology; Humans; Inosine; Mice; Molecular Sequence Data; Neoplasms; RNA Editing; RNA Precursors; RNA-Binding Proteins; RNA, Untranslated | 2007 |
Kinetics of nucleoside uptake by the basolateral side of the sheep choroid plexus epithelium perfused in situ.
Topics: Adenosine; Animals; Cell Polarity; Cell Survival; Choroid Plexus; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Epithelial Cells; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Inosine; Kinetics; Membrane Transport Proteins; Models, Biological; Nucleoside Transport Proteins; Nucleosides; Perfusion; Sheep; Sodium; Thioinosine; Thymidine; Uridine | 2008 |
Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common heterocyclic base, 4(7)-amino-6(5)H-imidazo[4,5-d]pyridazin-7(4)one.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Imidazoles; Inosine; Pyridazines; Structure-Activity Relationship | 2008 |
Sex differences in adenosine deaminase activity of stroke patients.
Topics: Adenosine; Adenosine Deaminase; Aged; Blood Chemical Analysis; Female; Humans; Inosine; Ischemia; Male; Middle Aged; Risk Factors; Sex Characteristics; Sex Factors; Stroke; Time Factors | 2008 |
Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Cell Hypoxia; Cell Line; Cell Survival; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Inosine; Mice; Myocytes, Cardiac; Nucleoside Transport Proteins; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A3; Thioinosine; Triazoles; Up-Regulation; Xanthines | 2008 |
The role of a purine-specific nucleoside hydrolase in spore germination of Bacillus thuringiensis.
Topics: Adenosine; Amino Acid Sequence; Bacillus thuringiensis; Cloning, Molecular; DNA, Bacterial; Enzyme Stability; Gene Deletion; Hydrogen-Ion Concentration; Inosine; Kinetics; Molecular Sequence Data; Mutagenesis, Insertional; N-Glycosyl Hydrolases; Sequence Alignment; Sequence Analysis, DNA; Spores, Bacterial; Temperature | 2008 |
Metabonomics in cancer diagnosis: mass spectrometry-based profiling of urinary nucleosides from breast cancer patients.
Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Artificial Intelligence; Biomarkers; Breast Neoplasms; Cytidine; False Negative Reactions; False Positive Reactions; Female; Guanosine; Humans; Inosine; Mass Spectrometry; Middle Aged; Nucleosides; Principal Component Analysis; Reproducibility of Results; Sensitivity and Specificity; Uridine | 2008 |
A-to-I RNA editing alters less-conserved residues of highly conserved coding regions: implications for dual functions in evolution.
Topics: Adenosine; Amino Acid Sequence; Animals; Conserved Sequence; Evolution, Molecular; Humans; Inosine; Insect Proteins; Insecta; Molecular Sequence Data; RNA Editing; Sequence Alignment; Shab Potassium Channels | 2008 |
Effects of sample preparation methods on the quantification of nucleosides in natural and cultured Cordyceps.
Topics: Adenosine; Calibration; Chromatography, High Pressure Liquid; Cordyceps; Culture Techniques; Deoxyadenosines; Drugs, Chinese Herbal; Guanosine; Inosine; Nucleosides; Powders; Reference Standards; Solvents; Temperature; Uridine | 2008 |
Simultaneous determination of adenosine and inosine using single-wall carbon nanotubes modified pyrolytic graphite electrode.
Topics: Adenosine; Electrodes; Graphite; Inosine; Methods; Nanotubes, Carbon; Oxidation-Reduction | 2008 |
A kinetic study of the rat liver adenosine kinase reverse reaction.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Ammonia; Animals; Inosine; Kinetics; Liver; Rats; Substrate Specificity | 2008 |
Frequency and fate of microRNA editing in human brain.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Brain; Humans; Inosine; Mice; MicroRNAs; Molecular Sequence Data; RNA Editing; RNA Precursors; RNA Processing, Post-Transcriptional; RNA-Binding Proteins | 2008 |
Estimation of adenosine and its major metabolites in brain tissues of rats using high-performance thin-layer chromatography-densitometry.
Topics: Adenosine; Animals; Brain; Brain Chemistry; Chromatography, Thin Layer; Densitometry; Inosine; Male; Rats; Rats, Wistar; Reproducibility of Results | 2008 |
Correlations of six related purine metabolites and diabetic nephropathy in Chinese type 2 diabetic patients.
Topics: Adenosine; Aged; Asian People; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Inosine; Male; Middle Aged; Purines; Uric Acid; Xanthine | 2009 |
A regulatory role of the Bateman domain of IMP dehydrogenase in adenylate nucleotide biosynthesis.
Topics: Adenosine; Catalysis; Escherichia coli; Escherichia coli Proteins; Guanosine Monophosphate; IMP Dehydrogenase; Inosine; Mutation; Protein Structure, Tertiary | 2009 |
Synthesis and antiviral evaluation of thieno[3,4-d]pyrimidine C-nucleoside analogues of 2',3'-dideoxy- and 2',3'-dideoxy-2',3'-didehydro-adenosine and -inosine.
Topics: Adenosine; Antiviral Agents; HIV; Inosine; Magnetic Resonance Spectroscopy; Pyrimidines; Spectrometry, Mass, Electrospray Ionization | 2009 |
Adenosine deamination to inosine in isolated basolateral membrane from kidney proximal tubule: implications for modulation of the membrane-associated protein kinase A.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Animals; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inosine; Kidney Tubules, Proximal; Receptor, Adenosine A1; Signal Transduction; Swine; Xanthines | 2009 |
TaqMan-based, real-time quantitative polymerase chain reaction method for RNA editing analysis.
Topics: Adenosine; Base Sequence; Humans; Inosine; Male; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Prefrontal Cortex; Receptors, Kainic Acid; Reproducibility of Results; RNA Editing; RNA, Messenger; Sensitivity and Specificity | 2009 |
Large-scale mRNA sequencing determines global regulation of RNA editing during brain development.
Topics: Adenosine; Adenosine Deaminase; Alternative Splicing; Animals; Blotting, Western; Brain; DNA, Complementary; Gene Expression Regulation, Developmental; Inosine; Mice; Mice, Inbred Strains; Receptor, Serotonin, 5-HT2C; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Sequence Analysis, DNA; Time Factors | 2009 |
Identification of the chloroplast adenosine-to-inosine tRNA editing enzyme.
Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Arabidopsis; Arabidopsis Proteins; Base Sequence; Chloroplasts; DNA, Plant; Gene Expression Regulation, Plant; Inosine; Molecular Sequence Data; RNA Editing; RNA, Plant; RNA, Small Interfering; RNA, Transfer, Amino Acyl; Subcellular Fractions | 2009 |
Widespread cleavage of A-to-I hyperediting substrates.
Topics: Adenosine; Alternative Splicing; Alu Elements; Animals; Catalytic Domain; Humans; Inosine; Mice; MicroRNAs; RNA Editing; RNA, Double-Stranded; RNA, Messenger; Sequence Alignment; Sequence Analysis, RNA; Templates, Genetic | 2009 |
Comparison of elimination and cardiovascular effects of adenine nucleosides administered intrapericardially or intravenously in anesthetized dog.
Topics: Adenosine; Animals; Blood Pressure; Body Fluids; Cardiotonic Agents; Dogs; Female; Heart Rate; Hemodynamics; Injections, Intravenous; Inosine; Male; Metabolic Clearance Rate; Myocardial Contraction; Pericardium | 2009 |
RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR.
Topics: Adenosine; Adenosine Deaminase; Animals; Apoptosis; Chlorocebus aethiops; eIF-2 Kinase; HeLa Cells; Humans; Inosine; Interferon Regulatory Factor-3; Measles; Measles virus; Mutation; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Viral; Vero Cells | 2009 |
Evidence that endogenous inosine and adenosine-mediated hyperglycaemia during ischaemia-reperfusion through A3 adenosine receptors.
Topics: Adenosine; Adenosine A3 Receptor Antagonists; Adenosine Triphosphate; Animals; Blood Glucose; Extremities; Glucose; Hyperglycemia; Inosine; Liver; Male; Rats; Rats, Wistar; Receptor, Adenosine A3; Reperfusion Injury | 2009 |
Recognition and coupling of A-to-I edited sites are determined by the tertiary structure of the RNA.
Topics: Adenosine; Animals; Base Sequence; Inosine; Mice; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; RNA; RNA Editing | 2009 |
Adenosine-to-inosine genetic recoding is required in the adult stage nervous system for coordinated behavior in Drosophila.
Topics: Adenosine; Adenosine Deaminase; Animals; Behavior, Animal; Drosophila melanogaster; Drosophila Proteins; Female; Inosine; Locomotion; Male; Nervous System; RNA Editing | 2009 |
Adenosine deamination in human transcripts generates novel microRNA binding sites.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Apoptosis Regulatory Proteins; Base Sequence; Binding Sites; Deamination; Humans; Inosine; MicroRNAs; Molecular Sequence Data; RNA Editing; RNA-Binding Proteins; Transcription, Genetic | 2009 |
Nucleoside map of the human central nervous system.
Topics: Adenosine; Adult; Brain; Brain Chemistry; Brain Mapping; Central Nervous System; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Female; Guanosine; Humans; Hypoxanthine; Inosine; Male; Middle Aged; Nucleosides; Spinal Cord; Uracil; Uridine; Xanthines | 2010 |
Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cell Death; Cell Hypoxia; Cytoprotection; Epithelial Cells; Glucose; Inosine; Kidney Tubular Necrosis, Acute; Kidney Tubules; L-Lactate Dehydrogenase; Mitochondria; Oxygen; Rats; Receptors, Purinergic P1 | 2009 |
A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins.
Topics: Adenosine; Alu Elements; Animals; Base Sequence; Computational Biology; Genome; Inosine; Mice; Molecular Sequence Data; Neurons; Phylogeny; RNA; RNA Editing; RNA-Binding Proteins; Sequence Analysis, RNA | 2010 |
A mammalian reporter system for fast and quantitative detection of intracellular A-to-I RNA editing levels.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Sequence; Genes, Reporter; HeLa Cells; Humans; Inosine; Luciferases; MicroRNAs; Molecular Sequence Data; RNA; RNA Editing; RNA-Binding Proteins | 2010 |
N-methyl-D-aspartate-evoked adenosine and inosine release from neurons requires extracellular calcium.
Topics: Adenosine; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Antagonists; Inosine; N-Methylaspartate; Neurons; Piperidines; Purines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2009 |
Nucleotides and nucleosides in ovine and caprine milk during lactation.
Topics: Adenosine; Adenosine Monophosphate; Animals; Cattle; Chromatography, High Pressure Liquid; Colostrum; Cytidine; Cytidine Monophosphate; Female; Goats; Guanosine; Inosine; Lactation; Milk; Nucleosides; Nucleotides; Uridine; Uridine Monophosphate | 2010 |
Age-related gene-specific changes of A-to-I mRNA editing in the human brain.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; Adult; Aged; Aged, 80 and over; Aging; Cerebral Cortex; Female; Humans; Inosine; Male; Middle Aged; Receptors, GABA-A; RNA Editing; Young Adult | 2010 |
Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates.
Topics: Adenosine; Alu Elements; Animals; Brain; Gene Expression Profiling; Genetic Variation; Genome, Human; Humans; Inosine; Macaca mulatta; Mutagenesis, Insertional; Pan troglodytes; Primates; RNA Editing | 2010 |
Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editing.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Animals; Cell Differentiation; Embryonic Stem Cells; Gene Expression Regulation, Enzymologic; Gene Silencing; Humans; Inosine; Mice; Neurons; Open Reading Frames; RNA Editing; RNA-Binding Proteins; RNA, Messenger | 2010 |
The relationship between oxygen and adenosine in astrocytic cultures.
Topics: Adenine Nucleotides; Adenosine; Animals; Astrocytes; Cell Culture Techniques; Cells, Cultured; Cerebral Cortex; Extracellular Fluid; Hypoxanthine; Hypoxia, Brain; Inosine; Oxygen; Oxygen Consumption; Rats | 2010 |
Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats.
Topics: Adenine Nucleotides; Adenosine; Animals; Animals, Newborn; Enzyme Inhibitors; Extracellular Fluid; Female; Hypoxia; In Vitro Techniques; Inosine; Male; Rats; Rats, Wistar; Spinal Cord | 2010 |
Lymphocyte-based determination of susceptibility to malignant hyperthermia: a pilot study in swine.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Calcium; Chromatography, High Pressure Liquid; Disease Susceptibility; Enzyme Inhibitors; Imidazoles; Inosine; Lymphocytes; Magnesium; Malignant Hyperthermia; Muscle Relaxants, Central; Oxazoles; Oxidative Phosphorylation; Pilot Projects; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Swine; Uncoupling Agents | 2010 |
Inosine cyanoethylation identifies A-to-I RNA editing sites in the human transcriptome.
Topics: Adenosine; Adenosine Deaminase; Alkylation; Alu Elements; Amino Acid Sequence; Base Sequence; DNA, Complementary; Exons; Gene Expression Profiling; Humans; Inosine; Molecular Sequence Data; RNA Editing; RNA-Binding Proteins; Serine-tRNA Ligase | 2010 |
Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats.
Topics: Adenosine; Alu Elements; Cell Line; Conserved Sequence; Humans; Inosine; Nuclear Proteins; Open Reading Frames; Organ Specificity; Proto-Oncogene Proteins c-fyn; RNA Editing; Skin | 2010 |
Adenosine-to-inosine RNA editing affects trafficking of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Topics: Adenosine; Adult; Amino Acid Substitution; Animals; Brain; Gene Expression; HEK293 Cells; Humans; Inosine; Mice; Protein Transport; Rats; Receptors, GABA-A; Recombinant Proteins; RNA Editing | 2011 |
Determination of the nucleosides and nucleobases in Tuber samples by dispersive solid-phase extraction combined with liquid chromatography-mass spectrometry.
Topics: Adenine; Adenosine; Agaricales; Chromatography, High Pressure Liquid; Chromatography, Liquid; Fermentation; Guanine; Guanosine; Hypoxanthine; Inosine; Mass Spectrometry; Nucleosides; Plant Extracts; Plant Tubers; Solid Phase Extraction; Tandem Mass Spectrometry; Uridine | 2011 |
An improved isolation procedure for adult mouse cardiomyocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Creatine; Cytological Techniques; Inosine; Isoproterenol; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac | 2011 |
A-to-I RNA editing is induced upon hypoxia.
Topics: Adenosine; Cell Adhesion Molecules; Cell Line; Deferoxamine; Epigenesis, Genetic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inosine; Male; Mediator Complex; Receptors, Cell Surface; RNA Editing; STAT3 Transcription Factor | 2011 |
Perturbing A-to-I RNA editing using genetics and homologous recombination.
Topics: Adenosine; Animals; Cloning, Molecular; Drosophila melanogaster; Inosine; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Recombination, Genetic; RNA; RNA Editing | 2011 |
Biochemical identification of A-to-I RNA editing sites by the inosine chemical erasing (ICE) method.
Topics: Adenosine; Animals; Inosine; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA Editing; Sequence Analysis, RNA | 2011 |
Biochemical detection of adenosine deaminase in Trypanosoma evansi.
Topics: Adenosine; Adenosine Deaminase; Animals; Chromatography, DEAE-Cellulose; Dogs; Inosine; Mice; Spectrophotometry; Trypanosoma | 2011 |
Adenosine deaminase from Streptomyces coelicolor: recombinant expression, purification and characterization.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Sequence; Animals; Bacterial Proteins; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Inosine; Models, Molecular; Molecular Sequence Data; Recombinant Proteins; Sequence Alignment; Streptomyces coelicolor | 2011 |
Low-temperature NMR studies on inosine wobble base pairs.
Topics: Adenosine; Base Pairing; Cold Temperature; Cytidine; DNA; Hydrogen Bonding; Inosine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Thermodynamics; Uridine | 2011 |
The pentose moiety of adenosine and inosine is an important energy source for the fermented-meat starter culture Lactobacillus sakei CTC 494.
Topics: Acetic Acid; Adenosine; Carbon Dioxide; Energy Metabolism; Ethanol; Formates; Hydrogen-Ion Concentration; Inosine; Lactobacillus; Meat; Pentoses | 2011 |
Elevated adenosine deaminase activity in overweight and obese Indian subjects.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Adolescent; Adult; Aged; Body Composition; Body Mass Index; Fasting; Female; Humans; India; Inosine; Insulin Resistance; Male; Middle Aged; Obesity | 2012 |
Absence of equilibrative nucleoside transporter 1 in ENT1 knockout mice leads to altered nucleoside levels following hypoxic challenge.
Topics: Adenosine; Animals; Cell Hypoxia; Cells, Cultured; Cyclic AMP; Equilibrative Nucleoside Transporter 1; Female; Gene Deletion; Gene Expression Regulation; Inosine; Mice; Mice, Knockout; Myocytes, Cardiac; Nucleosides; Protein Kinases; Receptors, Purinergic | 2011 |
Shedding of the coronary endothelial glycocalyx: effects of hypoxia/reoxygenation vs ischaemia/reperfusion.
Topics: Adenosine; Analysis of Variance; Animals; Coronary Vessels; Endothelium, Vascular; Glycocalyx; Guinea Pigs; Heparitin Sulfate; Histamine; Hypoxia; Inosine; Ischemia; Lactic Acid; Male; Microcirculation; Microscopy, Electron; Purines; Reperfusion; Syndecan-1; Tryptases | 2011 |
[Inefficient A-to-I RNA editing and ALS].
Topics: Adenosine; Adenosine Deaminase; Amyotrophic Lateral Sclerosis; Animals; Calcium; Catalysis; Humans; Inosine; Mice; Molecular Targeted Therapy; Motor Neurons; Receptors, AMPA; RNA Editing; RNA-Binding Proteins | 2010 |
Identification of widespread ultra-edited human RNAs.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Base Pair Mismatch; Base Pairing; Base Sequence; Exons; Expressed Sequence Tags; Genome; Genomics; Guanosine; Humans; Inosine; Molecular Sequence Data; RNA; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded | 2011 |
Mixed inhibition of adenosine deaminase activity by 1,3-dinitrobenzene: a model for understanding cell-selective neurotoxicity in chemically-induced energy deprivation syndromes in brain.
Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Amino Acid Sequence; Animals; Astrocytes; Binding Sites; Brain; Cattle; Cell Line; Dinitrobenzenes; Dose-Response Relationship, Drug; Energy Metabolism; Humans; Inosine; Kinetics; Mice; Models, Molecular; Molecular Sequence Data; Molecular Structure; Neurons; Neurotoxicity Syndromes; Protein Conformation; Protein Denaturation; Structure-Activity Relationship; Up-Regulation | 2012 |
Inosine, not adenosine, initiates endothelial glycocalyx degradation in cardiac ischemia and hypoxia.
Topics: Adenosine; Animals; Endothelium; Glycocalyx; Guinea Pigs; Hypoxia; In Vitro Techniques; Inosine; Myocardial Ischemia | 2011 |
Visualizing adenosine-to-inosine RNA editing in the Drosophila nervous system.
Topics: Adenosine; Adenosine Deaminase; Animals; Drosophila melanogaster; Genes, Reporter; Green Fluorescent Proteins; Inosine; Nervous System; RNA Editing | 2011 |
RNA editing underlies temperature adaptation in K+ channels from polar octopuses.
Topics: Acclimatization; Adenosine; Animals; Antarctic Regions; Inosine; Molecular Sequence Data; Octopodiformes; Recombinant Proteins; RNA Editing; Shaker Superfamily of Potassium Channels; Species Specificity; Xenopus laevis | 2012 |
Evolutionarily conserved A-to-I editing increases protein stability of the alternative splicing factor Nova1.
Topics: Adenosine; Alternative Splicing; Animals; Antigens, Neoplasm; Base Sequence; Brain; Chickens; Conserved Sequence; Evolution, Molecular; Gene Expression Regulation; Half-Life; HEK293 Cells; Humans; Inosine; Mice; Nerve Tissue Proteins; Neuro-Oncological Ventral Antigen; Nucleic Acid Conformation; Proteasome Endopeptidase Complex; Protein Stability; Proteolysis; RNA Editing; RNA Splice Sites; RNA-Binding Proteins; Transfection; Xenopus laevis | 2012 |
Making sense out of nonsense to visualize editing in the fly nervous system.
Topics: Adenosine; Adenosine Deaminase; Animals; Inosine; Nervous System; RNA Editing | 2012 |
Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.
Topics: Adenosine; Bacillus cereus; Binding Sites; Crystallography, X-Ray; Inosine; Models, Molecular; Protein Conformation; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship; Substrate Specificity | 2012 |
Anti-inflammatory effects of purine nucleosides, adenosine and inosine, in a mouse model of pleurisy: evidence for the role of adenosine A2 receptors.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, Animal; Female; Inosine; Leukocytes; Mice; Pleurisy; Purine Nucleosides; Receptors, Adenosine A2 | 2012 |
Systematic identification of edited microRNAs in the human brain.
Topics: Adenosine; Adenosine Deaminase; Algorithms; Brain; Computational Biology; Databases, Genetic; Genome, Human; Humans; Inosine; MicroRNAs; RNA Editing; RNA-Binding Proteins; Sequence Analysis, RNA | 2012 |
Development of a rapid, microplate-based kinetic assay for measuring adenosine deaminase activity in body fluids.
Topics: Adenosine; Adenosine Deaminase; Ascitic Fluid; Biological Assay; Body Fluids; Cerebrospinal Fluid; Enzyme Stability; Humans; Inosine; Kinetics; Pleural Effusion; Reference Standards; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 2012 |
A-to-I editing of microRNAs in the mammalian brain increases during development.
Topics: Adenosine; Animals; Base Sequence; Brain; Computational Biology; Dendrites; Embryo, Mammalian; Embryonic Development; Gene Expression Regulation, Developmental; High-Throughput Nucleotide Sequencing; Inosine; Mice; MicroRNAs; RNA Editing; RNA Isoforms; RNA-Binding Proteins; Transcriptome | 2012 |
Activity-dependent A-to-I RNA editing in rat cortical neurons.
Topics: Adenosine; Animals; Calcium; Cerebral Cortex; Inosine; Membrane Potentials; Neurons; Rats; RNA Editing; RNA, Messenger; Synapses; Time Factors | 2012 |
Quantification of adenosine-to-inosine editing of microRNAs using a conventional method.
Topics: Adenosine; Cloning, Molecular; Epigenomics; Inosine; MicroRNAs; Nucleic Acid Amplification Techniques; Reverse Transcriptase Polymerase Chain Reaction; RNA 3' Polyadenylation Signals; RNA Editing; RNA Precursors; Sequence Analysis, DNA | 2012 |
IGFBP7's susceptibility to proteolysis is altered by A-to-I RNA editing of its transcript.
Topics: Adenosine; Adenosine Deaminase; Base Sequence; Cell Adhesion; Cell Proliferation; Extracellular Matrix; Fibroblasts; Humans; Inosine; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Isoforms; Proteolysis; RNA Editing; RNA-Binding Proteins; Serine Endopeptidases; Tissue Distribution | 2012 |
Altered A-to-I RNA editing in human embryogenesis.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Deaminase; Alu Elements; BRCA1 Protein; CARD Signaling Adaptor Proteins; Cell Cycle Proteins; Cells, Cultured; Contractile Proteins; Embryonal Carcinoma Stem Cells; Embryonic Development; Embryonic Stem Cells; Fanconi Anemia Complementation Group C Protein; Filamins; Gene Expression; Gene Expression Regulation, Developmental; Guanylate Cyclase; Humans; Inosine; Intracellular Signaling Peptides and Proteins; Microfilament Proteins; Neoplasm Proteins; Nuclear Proteins; Protein Isoforms; Proto-Oncogene Proteins; RNA Editing; RNA-Binding Proteins; RNA, Messenger | 2012 |
The absence of A-to-I editing in the anticodon of plant cytoplasmic tRNA (Arg) ACG demands a relaxation of the wobble decoding rules.
Topics: Adenosine; Adenosine Deaminase; Anticodon; Base Pairing; Base Sequence; Cell Nucleus; Cell-Free System; Cytoplasm; Escherichia coli; Genetic Code; Glycine max; Inosine; Mitochondria; Molecular Sequence Data; Nucleic Acid Conformation; Protein Biosynthesis; RNA, Transfer, Arg; Sphagnopsida; Triticum | 2012 |
A novel computational strategy to identify A-to-I RNA editing sites by RNA-Seq data: de novo detection in human spinal cord tissue.
Topics: Adenosine; Algorithms; Brain; Computational Biology; Databases, Genetic; Exome; Gene Expression Regulation; Genome, Human; Genomics; Homeostasis; Humans; Inosine; Neurodegenerative Diseases; Reproducibility of Results; RNA Editing; Software; Spinal Cord; Transcriptome | 2012 |
Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Line, Tumor; Chromatography, Thin Layer; Diphosphates; Enzyme Assays; Extracellular Fluid; Fluorometry; Homeostasis; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Inosine; Luminescent Measurements; Lymphocytes; Neoplasm Metastasis; Nucleosides; Nucleotides; Pyrophosphatases | 2012 |
Purine metabolites in fibromyalgia syndrome.
Topics: Adenosine; Adult; Aged; Case-Control Studies; Female; Fibromyalgia; Humans; Hypoxanthine; Inosine; Middle Aged; Purines; Reference Values; Surveys and Questionnaires; Xanthine | 2013 |
miR-EdiTar: a database of predicted A-to-I edited miRNA target sites.
Topics: Adenosine; Binding Sites; Databases, Genetic; Gene Expression Regulation; Humans; Inosine; Internet; MicroRNAs; Nucleic Acid Conformation; RNA Editing | 2012 |
Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells.
Topics: Adenosine; Animals; Brain Neoplasms; Cell Line, Tumor; Female; Glioblastoma; Humans; Inosine; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Neoplasm Transplantation; RNA Editing; RNA, Neoplasm; Sequence Analysis, RNA; Transplantation, Heterologous | 2012 |
Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing.
Topics: Adenosine; Amino Acid Sequence; Animals; Cell Line; Humans; Inosine; Introns; Molecular Sequence Data; Morpholinos; Oligonucleotides, Antisense; Receptors, AMPA; RNA Editing; RNA Splicing | 2013 |
Sequence-dependent structural dynamics of primate adenosine-to-inosine editing substrates.
Topics: 2-Aminopurine; Adenosine; Animals; Base Sequence; Humans; Inosine; Inverted Repeat Sequences; Macaca mulatta; Molecular Probes; Nuclear Pore Complex Proteins; Nuclear Proteins; Nucleic Acid Denaturation; Pan troglodytes; RNA Editing; RNA Stability; Spectrometry, Fluorescence; Transition Temperature | 2012 |
Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury.
Topics: Adenosine; Cytoprotection; Hep G2 Cells; Humans; Inosine; Liver; Reperfusion Injury | 2013 |
Transcriptome-wide identification of A > I RNA editing sites by inosine specific cleavage.
Topics: Adenosine; Animals; Base Sequence; Brain; Genome; Genomics; Glyoxal; Guanosine; High-Throughput Nucleotide Sequencing; Inosine; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Ribonuclease T1; RNA; RNA Editing; RNA, Untranslated; Sequence Analysis, DNA; Sequence Analysis, RNA; Transcriptome | 2013 |
Tubuloglomerular feedback and renal function in mice with targeted deletion of the type 1 equilibrative nucleoside transporter.
Topics: Adenosine; Adenosine Deaminase; Animals; Arterial Pressure; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Female; Gene Deletion; Glomerular Filtration Rate; Heart Rate; Inosine; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Receptors, Purinergic P1; Renin | 2013 |
Identifying RNA editing sites using RNA sequencing data alone.
Topics: Adenosine; Alu Elements; Animals; Computational Biology; Drosophila melanogaster; Humans; Inosine; RNA Editing; Sequence Analysis, RNA | 2013 |
Oxidation of adenosine and inosine: the chemistry of 8-oxo-7,8-dihydropurines, purine iminoquinones, and purine quinones as observed by ultrafast spectroscopy.
Topics: Adenosine; Inosine; Molecular Structure; Oxidation-Reduction; Purines; Quinones; Spectrum Analysis | 2013 |
Importance of adenosine-to-inosine editing adjacent to the anticodon in an Arabidopsis alanine tRNA under environmental stress.
Topics: Adenosine; Adenosine Deaminase; Arabidopsis; Arabidopsis Proteins; Base Sequence; Cell Nucleus; Cold-Shock Response; Inosine; Mitochondria; Mutagenesis, Insertional; Nucleic Acid Conformation; Phenotype; Plant Leaves; Plant Roots; Protein Transport; RNA Editing; RNA Stability; RNA, Transfer, Ala | 2013 |
Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR).
Topics: Adenosine; Adenosine Deaminase; Alternative Splicing; Base Sequence; Cell Line, Tumor; Exons; Gene Expression Regulation; Humans; Inosine; RNA Editing; RNA Precursors; RNA-Binding Proteins; RNA, Messenger | 2013 |
ADAR-related activation of adenosine-to-inosine RNA editing during regeneration.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Brain Injuries; Cell Differentiation; Enzyme Activation; Extremities; Gene Expression Regulation; Inosine; Isoenzymes; Molecular Sequence Data; Myocardium; Nerve Regeneration; Notophthalmus viridescens; Receptors, GABA-A; Regeneration; RNA Editing; RNA-Binding Proteins; Signal Transduction | 2013 |
Prediction of constitutive A-to-I editing sites from human transcriptomes in the absence of genomic sequences.
Topics: Adenosine; Adenosine Deaminase; Base Sequence; Biocatalysis; Cell Line; Cluster Analysis; Genome, Human; Genomics; HeLa Cells; Humans; Inosine; Molecular Sequence Data; Polymerase Chain Reaction; Reproducibility of Results; RNA Editing; Sequence Analysis, RNA; Transcriptome | 2013 |
Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos.
Topics: Adenosine; Adenosine Deaminase; Animals; Blastocyst; Endonucleases; Gene Expression Regulation; Inosine; Mice; MicroRNAs; Multigene Family; Nuclear Proteins; Oocytes; RNA Editing; RNA Precursors; RNA-Binding Proteins | 2013 |
Involvement of CD73, equilibrative nucleoside transporters and inosine in rhythm and conduction disturbances mediated by adenosine A1 and A2A receptors in the developing heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Animals; Arrhythmias, Cardiac; Chick Embryo; Enzyme Activation; Equilibrative Nucleoside Transport Proteins; Gene Expression Regulation; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Inosine; Mitogen-Activated Protein Kinase 1; Myocardium; Phosphorylation; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction | 2013 |
Identification and analysis of the constituents in an aqueous extract of Tricholoma matsutake by HPLC coupled with diode array detection/electrospray ionization mass spectrometry.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Cytidine; Deoxyadenosines; Guanosine; Inosine; Phenylalanine; Riboflavin; Spectrometry, Mass, Electrospray Ionization; Thionucleosides; Tricholoma; Tryptophan; Tyrosine; Uridine; Water | 2013 |
Reduction of RNA A-to-I editing in Drosophila acclimated to heat shock.
Topics: Adaptation, Physiological; Adenosine; Animals; Drosophila; Hot Temperature; Inosine; RNA Editing | 2013 |
Perturbation of biogenesis and targeting of Epstein-Barr virus-encoded miR-BART3 microRNA by adenosine-to-inosine editing.
Topics: Adenosine; Base Sequence; Carcinoma; Carrier Proteins; Cell Line; Epstein-Barr Virus Infections; HEK293 Cells; Herpesvirus 4, Human; Humans; Inosine; MicroRNAs; Molecular Sequence Data; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; RNA Editing; Transcription Factors | 2013 |
Genome-wide analysis of A-to-I RNA editing by single-molecule sequencing in Drosophila.
Topics: Adenosine; Animals; Drosophila; Gene Expression; Genome, Insect; Inosine; RNA; RNA Editing | 2013 |
RADAR: a rigorously annotated database of A-to-I RNA editing.
Topics: Adenosine; Animals; Databases, Nucleic Acid; Deamination; Drosophila melanogaster; Humans; Inosine; Internet; Mice; Molecular Sequence Annotation; RNA Editing | 2014 |
Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Inosine; Interferon-alpha; Leukocytes, Mononuclear; Male; Mice; Mice, Knockout; Molecular Sequence Data; Nucleic Acid Conformation; RNA Editing; RNA, Viral; Toll-Like Receptor 7; Toll-Like Receptor 8 | 2014 |
Enzymatic interconversion of isomorphic fluorescent nucleosides: adenosine deaminase transforms an adenosine analogue into an inosine analogue.
Topics: Adenosine; Adenosine Deaminase; Inosine; Nucleosides | 2013 |
Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma.
Topics: Adenosine; Adenosine Deaminase; Carcinoma, Squamous Cell; Carrier Proteins; Cell Line, Tumor; Cohort Studies; Disease Progression; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Inosine; Oncogene Proteins; RNA Editing; RNA-Binding Proteins | 2014 |
Gender-related effects on urine L-cystine metastability.
Topics: Adenosine; Adult; Chemical Precipitation; Cysteine; Cystinuria; Female; Guanosine; Humans; Inosine; Male; Middle Aged; Sex Characteristics; Solubility; Vanilmandelic Acid | 2014 |
A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes.
Topics: Adenosine; Alu Elements; Animals; Base Sequence; Gene Expression Regulation; Genes; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Inosine; Primates; RNA Editing; Transcriptome | 2014 |
A biochemical landscape of A-to-I RNA editing in the human brain transcriptome.
Topics: Adenosine; Adult; Brain; Chromosomes, Human; Energy Metabolism; Gene Expression Profiling; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Inosine; Models, Genetic; Nervous System Diseases; RNA Editing; RNA, Messenger; Transcription, Genetic; Transcriptome | 2014 |
Improved design of hammerhead ribozyme for selective digestion of target RNA through recognition of site-specific adenosine-to-inosine RNA editing.
Topics: Adenosine; Animals; Brain; Inosine; Kinetics; Male; Mice; Mice, Inbred C57BL; Nucleic Acid Conformation; Receptor, Serotonin, 5-HT2C; RNA; RNA Cleavage; RNA Editing; RNA, Catalytic; Substrate Specificity | 2014 |
Alu elements shape the primate transcriptome by cis-regulation of RNA editing.
Topics: Adenosine; Alu Elements; Animals; Deamination; Gene Expression Regulation; Genome, Human; Humans; Inosine; Primates; RNA Editing; Transcriptome; Untranslated Regions | 2014 |
The dsRBP and inactive editor ADR-1 utilizes dsRNA binding to regulate A-to-I RNA editing across the C. elegans transcriptome.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; Binding Sites; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Inosine; Mutation; Protein Binding; RNA Editing; RNA, Double-Stranded; Transcriptome | 2014 |
Abnormal expression of an ADAR2 alternative splicing variant in gliomas downregulates adenosine-to-inosine RNA editing.
Topics: Adenosine; Adenosine Deaminase; Adolescent; Adult; Alternative Splicing; Astrocytoma; Case-Control Studies; Cell Line; Cell Line, Tumor; Central Nervous System Neoplasms; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Inosine; Middle Aged; Neuroglia; Reverse Transcriptase Polymerase Chain Reaction; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Young Adult | 2014 |
Human coding RNA editing is generally nonadaptive.
Topics: Adaptation, Biological; Adenosine; Computational Biology; Genes, Essential; Humans; Inosine; Phylogeny; RNA Editing; Statistics, Nonparametric | 2014 |
One hundred million adenosine-to-inosine RNA editing sites: hearing through the noise.
Topics: Adenosine; Alu Elements; Animals; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Inosine; Protein Biosynthesis; RNA Editing; Sequence Analysis, RNA | 2014 |
A novel method for measuring the ATP-related compounds in human erythrocytes.
Topics: Adenosine; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Erythrocyte Count; Erythrocytes; Homeostasis; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Inosine; Inosine Monophosphate; Sensitivity and Specificity; Uric Acid | 2014 |
A-to-I editing in the miRNA seed region regulates target mRNA selection and silencing efficiency.
Topics: 3' Untranslated Regions; Adenosine; HeLa Cells; Humans; Inosine; MicroRNAs; RNA Editing; RNA Interference; RNA, Messenger | 2014 |
Adenosine A1 receptor-dependent antinociception induced by inosine in mice: pharmacological, genetic and biochemical aspects.
Topics: Adenosine; Adenosine Deaminase; Analgesics; Animals; Female; Inosine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pain Measurement; Receptor, Adenosine A1 | 2015 |
The combination of Cl-IB-MECA with paclitaxel: a new anti-metastatic therapeutic strategy for melanoma.
Topics: Adenosine; Animals; Antineoplastic Agents; Cell Physiological Phenomena; Disease Progression; Drug Screening Assays, Antitumor; Humans; Inosine; Melanoma; Mice; Neoplasm Metastasis; Neoplasm Staging; Neovascularization, Pathologic; Paclitaxel; Receptor, Adenosine A3; Tumor Cells, Cultured | 2014 |
Effect of ecto-5'-nucleotidase (eN) in astrocytes on adenosine and inosine formation.
Topics: 5'-Nucleotidase; Adenosine; Animals; Astrocytes; Cell Hypoxia; Cells, Cultured; Coculture Techniques; Inosine; Ischemia; Mice; Mice, Knockout; Neurons | 2014 |
A genome-wide map of hyper-edited RNA reveals numerous new sites.
Topics: Adenosine; Adenosine Deaminase; Animals; Brain; Genome, Human; Humans; Inosine; Mice; MicroRNAs; Opossums; Platypus; Rats; RNA; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; Sequence Analysis, RNA | 2014 |
Identification of enzymes for adenosine-to-inosine editing and discovery of cytidine-to-uridine editing in nucleus-encoded transfer RNAs of Arabidopsis.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cell Nucleus; Cytidine; Cytosol; Genes, Essential; Genes, Reporter; Inosine; Molecular Sequence Data; Mutation; Phenotype; Phylogeny; RNA Editing; RNA, Plant; RNA, Transfer; Saccharomyces cerevisiae; Sequence Alignment; Sequence Analysis, DNA; Uridine | 2014 |
An expanding universe of mRNA modifications.
Topics: 5-Methylcytosine; Adenosine; Humans; Inosine; Pseudouridine; RNA Processing, Post-Transcriptional; RNA, Messenger; Saccharomyces cerevisiae | 2014 |
Inhibition of platelet activation and thrombus formation by adenosine and inosine: studies on their relative contribution and molecular modeling.
Topics: Adenosine; Animals; Blood Coagulation; Blood Platelets; Collagen; Humans; Inosine; Male; Mice; Models, Biological; Platelet Adhesiveness; Thrombosis | 2014 |
Large-scale detection and analysis of adenosine-to-inosine RNA editing during development in Plutella xylostella.
Topics: Adenosine; Amino Acid Sequence; Animals; Base Sequence; Computational Biology; DNA, Complementary; Evolution, Molecular; Female; Genome, Insect; Inosine; Life Cycle Stages; Male; Metamorphosis, Biological; Models, Molecular; Molecular Sequence Data; Moths; Open Reading Frames; Ovum; Phylogeny; Pupa; RNA Editing; Sequence Analysis, RNA; Therapeutic Irrigation | 2015 |
The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing.
Topics: Adenosine; Amino Acids; Animals; Base Sequence; Decapodiformes; Genome; Inosine; Molecular Sequence Data; Nervous System; RNA Editing; RNA, Messenger | 2015 |
A rapid enzymatic assay for high-throughput screening of adenosine-producing strains.
Topics: Adenosine; Adenosine Deaminase; Ammonia; Bacteria; Enzyme Assays; High-Throughput Screening Assays; Indophenol; Inosine; Reproducibility of Results; Staining and Labeling | 2015 |
Overexpression of adenosine deaminase acting on RNA 1 in chordoma tissues is associated with chordoma pathogenesis by reducing miR‑125a and miR‑10a expression.
Topics: Adenosine; Adenosine Deaminase; Cell Line, Tumor; Cell Proliferation; Chordoma; Humans; Inosine; MicroRNAs; RNA-Binding Proteins; RNA, Messenger | 2015 |
Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Inosine; Luciferases; Melanoma; Mice; Mice, Nude; MicroRNAs; Molecular Sequence Data; mRNA Cleavage and Polyadenylation Factors; Neoplasm Metastasis; Neoplasm Transplantation; RNA Editing; RNA-Binding Proteins; Skin Neoplasms; Transcription Factors | 2015 |
Noncoding regions of C. elegans mRNA undergo selective adenosine to inosine deamination and contain a small number of editing sites per transcript.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; Base Pairing; Base Sequence; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Deamination; Exons; High-Throughput Nucleotide Sequencing; Inosine; Introns; Molecular Sequence Data; Nucleic Acid Conformation; Open Reading Frames; RNA Editing; RNA, Helminth | 2015 |
Transcriptome-wide identification of adenosine-to-inosine editing using the ICE-seq method.
Topics: Adenosine; Biochemistry; Brain; Cells, Cultured; DNA, Complementary; Gene Expression Profiling; Gene Library; Genome; High-Throughput Nucleotide Sequencing; Humans; Inosine; Polymorphism, Single Nucleotide; RNA Editing; Software | 2015 |
Aberrant alternative splicing pattern of ADAR2 downregulates adenosine-to-inosine editing in glioma.
Topics: Adenosine; Adenosine Deaminase; Alternative Splicing; Astrocytes; Cell Line, Tumor; Exons; Gene Expression Regulation, Neoplastic; Glioma; Humans; Inosine; RNA Editing; RNA Splicing; RNA-Binding Proteins; RNA, Messenger | 2015 |
Cis regulatory effects on A-to-I RNA editing in related Drosophila species.
Topics: Adenosine; Adenosine Deaminase; Animals; Drosophila; Drosophila Proteins; Female; Inosine; Male; Nucleic Acid Conformation; Regulatory Elements, Transcriptional; RNA Editing; RNA, Double-Stranded; RNA, Messenger | 2015 |
Modifying microRNAs--another piece of the melanoma puzzle.
Topics: Adenosine; Animals; Female; Gene Expression Regulation, Neoplastic; Humans; Inosine; Melanocytes; Melanoma; MicroRNAs; RNA Editing; Skin Neoplasms | 2015 |
Biochemical and Transcriptome-Wide Identification of A-to-I RNA Editing Sites by ICE-Seq.
Topics: Adenosine; Adenosine Deaminase; Gene Expression Profiling; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Inosine; RNA Editing; Sequence Analysis, RNA; Transcriptome | 2015 |
Identification of an RNA element for specific coordination of A-to-I RNA editing on HTR2C pre-mRNA.
Topics: Adenosine; Adenosine Deaminase; Humans; Inosine; Mutation; Nucleic Acid Conformation; Receptor, Serotonin, 5-HT2C; Regulatory Sequences, Ribonucleic Acid; RNA Editing; RNA Precursors | 2015 |
Extracellular Adenosine Formation by Ecto-5'-Nucleotidase (CD73) Is No Essential Trigger for Early Phase Ischemic Preconditioning.
Topics: 5'-Nucleotidase; Adenosine; Animals; Disease Models, Animal; Extracellular Space; Female; Inosine; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Knockout; Myocardial Infarction; Myocardial Ischemia; Sex Factors; Ventricular Function, Left | 2015 |
RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; DEAD-box RNA Helicases; Embryo Loss; Gene Deletion; Gene Knock-In Techniques; Inosine; Interferon-Induced Helicase, IFIH1; Mice; Mice, Mutant Strains; Mutation; Nucleic Acid Conformation; RNA Editing; RNA, Double-Stranded; Transcription, Genetic | 2015 |
The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.
Topics: Adenosine; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Genome, Human; Humans; Inosine; Neoplasms; RNA Editing | 2015 |
Watson-Crick hydrogen bonding of unlocked nucleic acids.
Topics: Adenosine; Base Pairing; Base Sequence; Hydrogen Bonding; Inosine; Nucleic Acid Conformation; Oligoribonucleotides; RNA; RNA Stability; Thermodynamics | 2015 |
Cancer genomics: The relevance of extensive editing in tumour transcriptomes.
Topics: Adenosine; Humans; Inosine; Neoplasms; RNA Editing | 2015 |
Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease.
Topics: Adenosine; Adenosine Deaminase; Alzheimer Disease; Epigenesis, Genetic; Frontal Lobe; High-Throughput Nucleotide Sequencing; Hippocampus; Humans; Inosine; Microfluidics; Polymerase Chain Reaction; RNA Editing; RNA Precursors; RNA-Binding Proteins; RNA, Double-Stranded; Temporal Lobe | 2016 |
Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development.
Topics: Adenosine; Antimalarials; Dipyridamole; Drug Discovery; Equilibrative Nucleoside Transporter 1; Guanosine; Humans; Inhibitory Concentration 50; Inosine; Malaria, Falciparum; Malaria, Vivax; Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport Proteins; Plasmodium falciparum; Plasmodium vivax; Polymorphism, Single Nucleotide; Protozoan Proteins; Purines; Pyrimidines; Saccharomyces cerevisiae; Uridine | 2016 |
Genome-wide A-to-I RNA editing in fungi independent of ADAR enzymes.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Substitution; Codon, Terminator; DNA, Complementary; Fungi; Gene Expression Regulation, Fungal; Genome-Wide Association Study; Genome, Fungal; Inosine; Mutation; Reproduction; RNA Editing; RNA-Binding Proteins; Transcription, Genetic | 2016 |
Computer Simulations Reveal Substrate Specificity of Glycosidic Bond Cleavage in Native and Mutant Human Purine Nucleoside Phosphorylase.
Topics: Adenosine; Amino Acid Substitution; Biocatalysis; Catalytic Domain; Databases, Protein; Energy Transfer; Guanosine; Humans; Hydrogen Bonding; Hydrolysis; Inosine; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Mutant Proteins; Mutation; Purine-Nucleoside Phosphorylase; Static Electricity; Substrate Specificity | 2016 |
Novel modes of RNA editing in mitochondria.
Topics: Adenosine; Deamination; Euglenozoa; Genes, Mitochondrial; Genes, rRNA; Inosine; Mitochondria; RNA; RNA Editing; RNA, Mitochondrial; Trans-Splicing; Transcriptome | 2016 |
Where have all the inosines gone? Conflicting evidence for A-to-I editing of the anticodon of higher eukaryotic tRNAACGArg questions the dogma of a universal wobble-mediated decoding of CGN codons.
Topics: Adenosine; Anticodon; Codon; Cytoplasm; Eukaryotic Cells; Genetic Code; Humans; Inosine; RNA Editing; RNA, Transfer, Arg | 2016 |
Adenosine to Inosine editing frequency controlled by splicing efficiency.
Topics: Adenosine; Adenosine Deaminase; Animals; Exons; Genes, Reporter; HEK293 Cells; Humans; Inosine; Introns; Mice; Nucleic Acid Conformation; Protein Processing, Post-Translational; RNA Editing; RNA Precursors; RNA Splicing; RNA-Binding Proteins | 2016 |
Triplex-forming peptide nucleic acid modified with 2-aminopyridine as a new tool for detection of A-to-I editing.
Topics: Adenosine; Aminopyridines; Fluorescence; Hydrogen-Ion Concentration; Inosine; Peptide Nucleic Acids | 2016 |
Controlling the Editor: The Many Roles of RNA-Binding Proteins in Regulating A-to-I RNA Editing.
Topics: Adenosine; Adenosine Deaminase; Anemia, Macrocytic; Animals; Base Pairing; Caenorhabditis elegans Proteins; Chromosome Deletion; Chromosomes, Human, Pair 5; Drosophila Proteins; Humans; Inosine; Mice; Nervous System Diseases; Nucleic Acid Conformation; RNA Editing; RNA Splicing; RNA-Binding Proteins; RNA, Double-Stranded; Spliceosomes; Transcriptome | 2016 |
Analysis of Trinitrophenylated Adenosine and Inosine by Capillary Electrophoresis and γ-Cyclodextrin-Enhanced Fluorescence Detection.
Topics: Adenosine; Animals; Brain; Electrophoresis, Capillary; gamma-Cyclodextrins; Inosine; Kinetics; Magnetic Resonance Spectroscopy; Rats; Spectrometry, Fluorescence; Trinitrobenzenesulfonic Acid | 2016 |
Dynamic regulation of RNA editing in human brain development and disease.
Topics: Adenosine; Adenosine Deaminase; Brain; Diagnosis; Gene Ontology; Humans; Inosine; RNA Editing; RNA-Binding Proteins | 2016 |
Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis.
Topics: Adenosine; Adenosine Deaminase; Animals; Cluster Analysis; Erythrocyte Indices; Erythroid Cells; Erythropoiesis; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Granulocytes; Hematopoietic Stem Cell Transplantation; Inosine; Interferons; Mice; MicroRNAs; Myelopoiesis; Organ Specificity; Phenotype; Receptors, Interferon; Retroelements; RNA Editing; RNA-Binding Proteins; Signal Transduction; Transcription, Genetic | 2016 |
The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection.
Topics: Adenosine; Animals; Conserved Sequence; Drosophila; Evolution, Molecular; Exons; Inosine; Phylogeny; RNA Editing; Selection, Genetic; Transcriptome | 2016 |
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Adult; Aged; Aged, 80 and over; Aortic Aneurysm; Atherosclerosis; Carotid Artery Diseases; Cathepsins; Coronary Artery Disease; ELAV-Like Protein 1; Female; Fluorescent Antibody Technique; Gene Expression Regulation; Gene Knock-In Techniques; Gene Knockdown Techniques; High-Throughput Nucleotide Sequencing; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia; Immunoblotting; Inosine; Interferon-gamma; Male; Middle Aged; Real-Time Polymerase Chain Reaction; RNA Editing; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; Sequence Analysis, RNA; Tumor Necrosis Factor-alpha | 2016 |
Role of Host-Driven Mutagenesis in Determining Genome Evolution of Sigma Virus (DMelSV; Rhabdoviridae) in Drosophila melanogaster.
Topics: Adenosine; Animals; Drosophila melanogaster; Genome, Viral; Host-Pathogen Interactions; Inosine; Insect Viruses; Mutagenesis; Mutation Rate; Polymorphism, Genetic; Rhabdoviridae; RNA Editing | 2016 |
A LC-MS/MS Method for Quantifying Adenosine, Guanosine and Inosine Nucleotides in Human Cells.
Topics: Adenosine; Chromatography, Liquid; Dried Blood Spot Testing; Erythrocytes; Guanosine; Humans; Inosine; Leukocytes, Mononuclear; Nucleotides; Tandem Mass Spectrometry | 2017 |
LNCediting: a database for functional effects of RNA editing in lncRNAs.
Topics: Adenosine; Animals; Databases, Nucleic Acid; Drosophila melanogaster; Humans; Inosine; Macaca mulatta; Mice; MicroRNAs; Nucleic Acid Conformation; RNA Editing; RNA, Long Noncoding | 2017 |
PAI: Predicting adenosine to inosine editing sites by using pseudo nucleotide compositions.
Topics: Adenosine; Animals; Drosophila melanogaster; Entomology; Inosine; Molecular Biology; Nucleotides; RNA Editing | 2016 |
Discriminative Prediction of A-To-I RNA Editing Events from DNA Sequence.
Topics: Adenosine; Animals; Base Sequence; Computational Biology; Computer Simulation; DNA; Genome, Human; Humans; Inosine; Machine Learning; Mice; RNA Editing | 2016 |
ADARB1 catalyzes circadian A-to-I editing and regulates RNA rhythm.
Topics: Adenosine; Adenosine Deaminase; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Circadian Rhythm; Cryptochromes; Gene Expression Regulation; Humans; Inosine; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA; RNA-Binding Proteins; Transcription, Genetic | 2017 |
Changes in cardiac nucleotide metabolism in Huntington's disease.
Topics: Adenosine; Adenosine Deaminase; AMP Deaminase; Animals; Disease Models, Animal; Humans; Huntington Disease; Inosine; Mice; Myocardium; Purine-Nucleoside Phosphorylase; Pyrophosphatases | 2016 |
Modification of orthogonal tRNAs: unexpected consequences for sense codon reassignment.
Topics: Adenosine; Anticodon; Codon; Evolution, Molecular; Genetic Engineering; Green Fluorescent Proteins; Histidine; Inosine; Methanococcus; RNA, Transfer | 2016 |
iRNA-AI: identifying the adenosine to inosine editing sites in RNA sequences.
Topics: Adenosine; Algorithms; Computational Biology; Humans; Inosine; RNA Editing; RNA, Messenger; Sequence Analysis, RNA; Software; Support Vector Machine | 2017 |
Thermodynamics of the Purine Nucleoside Phosphorylase Reaction Revealed by Computer Simulations.
Topics: Adenosine; Animals; Biocatalysis; Catalytic Domain; Cattle; Guanosine; Humans; Inosine; Kinetics; Linear Models; Molecular Dynamics Simulation; Molecular Structure; Mutation; Protein Binding; Protein Domains; Purine-Nucleoside Phosphorylase; Static Electricity; Substrate Specificity; Thermodynamics | 2017 |
A-to-I RNA editing promotes developmental stage-specific gene and lncRNA expression.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Gene Expression Regulation, Developmental; Inosine; Mutation; RNA Editing; RNA, Long Noncoding | 2017 |
Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development.
Topics: Adenosine; Adenosine Deaminase; alpha Karyopherins; Animals; Cell Differentiation; Cell Nucleus; Cells, Cultured; Cerebral Cortex; HEK293 Cells; Humans; Inosine; Mice; Models, Biological; Neurogenesis; Neurons; NIMA-Interacting Peptidylprolyl Isomerase; Nuclear Localization Signals; Protein Binding; Rats; RNA Editing | 2017 |
Construction of a guide-RNA for site-directed RNA mutagenesis utilising intracellular A-to-I RNA editing.
Topics: Adenosine; Adenosine Deaminase; Base Sequence; Codon; HEK293 Cells; Humans; Inosine; Intracellular Space; Mutagenesis, Site-Directed; Protein Domains; RNA Editing; RNA-Binding Proteins; RNA, Guide, Kinetoplastida | 2017 |
Identification of Diverse Adenosine-to-Inosine RNA Editing Subtypes in Colorectal Cancer.
Topics: Adenosine; Biomarkers, Tumor; Cell Line, Tumor; Colorectal Neoplasms; Gene Expression Profiling; Humans; Inosine; Reproducibility of Results; RNA Editing; Sequence Analysis, DNA; Transcriptome | 2017 |
A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Breast; Breast Neoplasms; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Inosine; MCF-7 Cells; MicroRNAs; RNA Editing; RNA-Binding Proteins; Tetrahydrofolate Dehydrogenase; Up-Regulation | 2017 |
The RNA code comes into focus.
Topics: Adenosine; Antibodies; Epigenomics; Inosine; RNA, Bacterial; RNA, Messenger; Transcription, Genetic; Transcriptome | 2017 |
Abnormalities in A-to-I RNA editing patterns in CNS injuries correlate with dynamic changes in cell type composition.
Topics: Adenosine; Animals; Astrocytes; Cerebral Cortex; Female; Inosine; Mice; Microglia; Neurons; Oligodendroglia; Organ Specificity; Primary Cell Culture; RNA; RNA Editing; Spinal Cord; Spinal Cord Injuries | 2017 |
Adaptation of A-to-I RNA editing in Drosophila.
Topics: Adenosine; Animals; Conserved Sequence; Drosophila; Drosophila melanogaster; Epigenesis, Genetic; Female; Gene Expression Profiling; Genome, Insect; Inosine; Male; Mutation; Nucleotides; Protein Folding; RNA; RNA Editing; Species Specificity; Synaptic Transmission; Temperature | 2017 |
Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers.
Topics: Adenosine; Female; Genes, Tumor Suppressor; Humans; Inosine; Leukemia Inhibitory Factor Receptor alpha Subunit; Male; MicroRNAs; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms; RNA Editing; RNA, Neoplasm; Zinc Finger E-box Binding Homeobox 2; Zinc Finger E-box-Binding Homeobox 1 | 2017 |
A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervical cancer.
Topics: Adenosine; Adenosine Deaminase; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Humans; Inosine; Interleukin-6; Mutation; Neoplasm Proteins; Nucleotide Motifs; Phosphorylation; RNA Editing; RNA-Binding Proteins; Signal Transduction; STAT3 Transcription Factor; Uterine Cervical Neoplasms | 2017 |
Comparison of the Human A
Topics: Adenosine; Binding Sites; Humans; Inosine; Molecular Dynamics Simulation; Protein Binding; Protein Structure, Tertiary; Receptor, Adenosine A2A | 2017 |
A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme.
Topics: Adenosine; Adenosine Deaminase; Autopsy; Base Pairing; Brain Neoplasms; Case-Control Studies; Corpus Callosum; Frontal Lobe; Gene Expression Regulation, Neoplastic; Gene Library; Glioblastoma; Gray Matter; HEK293 Cells; Humans; Inosine; MicroRNAs; Nucleic Acid Conformation; RNA Editing; RNA Stability; RNA-Binding Proteins; Thermodynamics; White Matter | 2017 |
Visualizing adenosine-to-inosine RNA editing in single mammalian cells.
Topics: Adenosine; Cell Line; Humans; In Situ Hybridization, Fluorescence; Inosine; Molecular Imaging; Neurons; Optical Imaging; RNA Editing | 2017 |
Restricting retrotransposons: ADAR1 is another guardian of the human genome.
Topics: Adenosine; Adenosine Deaminase; Autoimmune Diseases of the Nervous System; Biological Assay; Genome, Human; HeLa Cells; Humans; Inosine; Long Interspersed Nucleotide Elements; Nervous System Malformations; Ribonucleoproteins; RNA; RNA Editing; RNA-Binding Proteins; RNA, Small Interfering | 2017 |
Detection of a Subset of Posttranscriptional Transfer RNA Modifications in Vivo with a Restriction Fragment Length Polymorphism-Based Method.
Topics: Adenosine; Adenosine Deaminase; Amplified Fragment Length Polymorphism Analysis; Base Pairing; Computational Biology; Deamination; Expert Systems; HeLa Cells; Humans; Hydrogen-Ion Concentration; Inosine; Models, Biological; Polymorphism, Restriction Fragment Length; Reverse Transcription; RNA Interference; RNA Processing, Post-Transcriptional; RNA, Small Interfering; RNA, Transfer, Ala; RNA, Transfer, Thr; RNA, Transfer, Val; Substrate Specificity | 2017 |
Dynamic hyper-editing underlies temperature adaptation in Drosophila.
Topics: Acclimatization; Adaptation, Physiological; Adenosine; Adenosine Deaminase; Animals; Behavior, Animal; Brain; Drosophila melanogaster; Drosophila Proteins; Exons; Inosine; Mutation; Nucleic Acid Conformation; RNA; RNA Editing; Temperature | 2017 |
Population and allelic variation of A-to-I RNA editing in human transcriptomes.
Topics: Adenosine; Alleles; Cell Line, Tumor; Genetic Variation; Genome-Wide Association Study; Genome, Human; Humans; Inosine; Lymphocytes; Quantitative Trait Loci; RNA; RNA Editing; Sequence Analysis, RNA; Transcriptome | 2017 |
Methods for the Detection of Adenosine-to-Inosine Editing Events in Cellular RNA.
Topics: Adenosine; Animals; Humans; Inosine; Reverse Transcriptase Polymerase Chain Reaction; RNA Editing; RNA, Messenger; Sequence Analysis, RNA | 2017 |
A-to-I RNA editing is developmentally regulated and generally adaptive for sexual reproduction in
Topics: Adaptation, Biological; Adenosine; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Inosine; Meiosis; Neurospora; Neurospora crassa; Reproduction; RNA; RNA Editing; RNA Interference | 2017 |
Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.
Topics: Adenosine; Adenosine Deaminase; Alleles; Animals; Brain; Female; Growth and Development; Homeostasis; Immunity, Innate; Inosine; Interferon-Induced Helicase, IFIH1; Male; Mice; Mice, Inbred C57BL; RNA Editing; Transcriptome | 2017 |
Codon adaptation to tRNAs with Inosine modification at position 34 is widespread among Eukaryotes and present in two Bacterial phyla.
Topics: Adenosine; Amino Acids; Anticodon; Biological Evolution; Codon; Cyanobacteria; Eukaryota; Firmicutes; Genetic Code; Humans; Inosine; Protein Biosynthesis; RNA, Messenger; RNA, Transfer, Arg; Transcriptome | 2018 |
Determination of the Main Nucleosides and Nucleobases in Natural and Cultured Ophiocordyceps xuefengensis.
Topics: Adenine; Adenosine; Animals; Chromatography, High Pressure Liquid; Clerodendrum; Cordyceps; Fruiting Bodies, Fungal; Guanosine; Inosine; Larva; Moths; Nucleosides; Uracil; Uridine | 2017 |
The
Topics: Adenosine; Adenosine Deaminase; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chemotaxis; Gene Expression Profiling; Gene Expression Regulation; Inosine; RNA, Messenger | 2017 |
Large-scale prediction of ADAR-mediated effective human A-to-I RNA editing.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Alternative Splicing; Base Sequence; Computational Biology; Databases, Nucleic Acid; Female; Gene Ontology; Humans; Inosine; Male; MicroRNAs; Mutation, Missense; RNA Editing; RNA Precursors; RNA-Binding Proteins; Sequence Analysis, RNA; Software; Support Vector Machine; Tissue Distribution | 2019 |
Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance.
Topics: Adenosine; Adenosine Deaminase; Animals; Conserved Sequence; Humans; Inosine; RNA Editing; RNA, Double-Stranded; Xenopus | 2017 |
Site-directed RNA editing by adenosine deaminase acting on RNA for correction of the genetic code in gene therapy.
Topics: Adenosine; Adenosine Deaminase; Alleles; Blotting, Western; Codon, Terminator; Genetic Code; Genetic Therapy; Green Fluorescent Proteins; Humans; Inosine; Point Mutation; RNA Editing; RNA-Binding Proteins; RNA, Guide, Kinetoplastida | 2017 |
An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; HEK293 Cells; Humans; Inosine; Neoplasms; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; Tumor Cells, Cultured | 2017 |
Linkage of A-to-I RNA Editing in Metazoans and the Impact on Genome Evolution.
Topics: Adaptation, Physiological; Adenosine; Animals; Cephalopoda; Drosophila; Evolution, Molecular; Genetic Linkage; Genome; Humans; Inosine; Linkage Disequilibrium; Mice; Open Reading Frames; Phylogeny; Proteomics; RNA; RNA Editing; Selection, Genetic | 2018 |
Promoting RNA editing by ADAR attraction.
Topics: Adenosine; Adenosine Deaminase; Animals; Inosine; RNA Editing; Transcriptome | 2017 |
Editing inducer elements increases A-to-I editing efficiency in the mammalian transcriptome.
Topics: Adenosine; Adenosine Deaminase; Animals; GluK2 Kainate Receptor; HEK293 Cells; HeLa Cells; Humans; Inosine; Kv1.1 Potassium Channel; Mice; MicroRNAs; Nucleic Acid Conformation; Receptors, AMPA; Receptors, Kainic Acid; Regulatory Sequences, Ribonucleic Acid; RNA Editing; Transcriptome | 2017 |
Structure-mediated modulation of mRNA abundance by A-to-I editing.
Topics: Adenosine; Adenosine Deaminase; Argonaute Proteins; Gene Expression Regulation; Gene Knockdown Techniques; Hep G2 Cells; Humans; Inosine; K562 Cells; MicroRNAs; RNA Editing; RNA Stability; RNA-Binding Proteins; RNA, Messenger | 2017 |
Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.
Topics: Adenosine; Codon, Nonsense; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Inosine; Mutagenesis, Site-Directed; Mutation; RNA Editing; RNA, Guide, Kinetoplastida; Transcriptome; Transfection | 2018 |
Mechanistic implications of enhanced editing by a HyperTRIBE RNA-binding protein.
Topics: Adenosine; Adenosine Deaminase; Animals; Binding Sites; Catalytic Domain; Drosophila Proteins; Heterogeneous-Nuclear Ribonucleoproteins; Inosine; Mutation; Recombinant Fusion Proteins; RNA Editing; RNA-Binding Proteins; Sequence Analysis, RNA | 2018 |
RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure.
Topics: Adenosine; Adenosine Deaminase; Base Composition; Cell Line, Tumor; Deamination; Hep G2 Cells; Humans; Inosine; Nucleic Acid Conformation; Protein Biosynthesis; RNA Editing; RNA Interference; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Messenger; RNA, Small Interfering; Transcriptome | 2017 |
Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets.
Topics: 3' Untranslated Regions; Adenosine; Binding Sites; Gene Expression Regulation, Neoplastic; Humans; Inosine; MicroRNAs; Neoplasms; RNA Editing; Survival Analysis | 2018 |
Comparison of the diastereoisomeric excess of uridine, inosine and adenosine cyanohydrins determined by HPLC-DAD and
Topics: Adenosine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Inosine; Magnetic Resonance Spectroscopy; Nitriles; Stereoisomerism; Uridine | 2017 |
ADAR2/miR-589-3p axis controls glioblastoma cell migration/invasion.
Topics: Adenosine; Adenosine Deaminase; Adult; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; HEK293 Cells; Humans; Inosine; Male; MicroRNAs; Neoplasm Invasiveness; RNA Editing; RNA-Binding Proteins | 2018 |
Adenosine-to-Inosine Editing of MicroRNA-487b Alters Target Gene Selection After Ischemia and Promotes Neovascularization.
Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Chromosomal Proteins, Non-Histone; Humans; Inosine; Ischemia; Methylation; Mice; Mice, Inbred C57BL; MicroRNAs; Muscle, Skeletal; Neovascularization, Physiologic; RNA Editing; RNA Interference; RNA-Binding Proteins; RNA, Small Interfering; Up-Regulation | 2018 |
An Evolutionary Landscape of A-to-I RNA Editome across Metazoan Species.
Topics: Adenosine; Animals; Cluster Analysis; Evolution, Molecular; Humans; Inosine; RNA; RNA Editing; Sequence Analysis, RNA | 2018 |
N
Topics: Adenosine; Adenosine Deaminase; Cell Line, Tumor; Gene Expression Regulation; HEK293 Cells; HeLa Cells; Humans; Inosine; Methyltransferases; RNA; RNA Editing; RNA-Binding Proteins | 2018 |
A-to-I RNA editing in the rat brain is age-dependent, region-specific and sensitive to environmental stress across generations.
Topics: Adenosine; Adenosine Deaminase; Age Factors; Animals; Brain; Environment; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation; Gene-Environment Interaction; Inosine; Organ Specificity; Rats; Receptor, Serotonin, 5-HT2C; RNA; RNA Editing; Stress, Physiological | 2018 |
A survey on cellular RNA editing activity in response to Candida albicans infections.
Topics: Adenosine; Alu Elements; Animals; Candida albicans; Candidiasis; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inosine; Mice; RNA Editing; RNA-Binding Proteins; Sequence Analysis, RNA; Signal Transduction | 2018 |
A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression.
Topics: 3' Untranslated Regions; Adenosine; Animals; Cell Line, Tumor; Cell Proliferation; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Inosine; Melanoma; Mice; Mice, Nude; Microfilament Proteins; MicroRNAs; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogenes; RNA Editing; Skin Neoplasms | 2018 |
Topics: Adenosine; Adenosine Deaminase; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Inosine; Mutation; Ribonuclease III; RNA Editing; RNA Interference; RNA-Dependent RNA Polymerase; RNA, Double-Stranded; RNA, Small Interfering | 2018 |
Performance comparison between multienzymes loaded single and dual electrodes for the simultaneous electrochemical detection of adenosine and metabolites in cancerous cells.
Topics: A549 Cells; Adenosine; Adenosine Deaminase; Biosensing Techniques; Electrodes; Humans; Hypoxanthine; Inosine; Limit of Detection; Metabolomics; Neoplasms; Purine-Nucleoside Phosphorylase; Xanthine Oxidase | 2018 |
Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis.
Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Cells, Cultured; Connective Tissue Growth Factor; Copper-Transporting ATPases; Escherichia coli Proteins; Female; Filamins; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Humans; Inosine; Keratinocytes; Male; Middle Aged; Psoriasis; RNA Editing; RNA, Double-Stranded; Young Adult | 2018 |
A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer.
Topics: Adenosine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Databases, Genetic; Gene Expression Regulation, Neoplastic; Humans; Inosine; Proteomics; RNA Editing; Sequence Analysis, RNA; Tandem Mass Spectrometry | 2018 |
RNA editing in nascent RNA affects pre-mRNA splicing.
Topics: Adenosine; Animals; Chromatin; Exons; Gene Expression Regulation; Humans; Inosine; Mammals; Nucleic Acid Conformation; Polyadenylation; RNA Editing; RNA Precursors; RNA Splicing | 2018 |
Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer.
Topics: Adenosine; Adenosine Deaminase; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; DEAD-box RNA Helicases; Deamination; Doxorubicin; HEK293 Cells; Humans; Inosine; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Neoplasm Proteins; Neoplasms; RNA Editing; RNA Interference; RNA-Binding Proteins; Xenograft Model Antitumor Assays | 2018 |
Lactobacillus gasseri PA-3, but not L. gasseri OLL2996, reduces the absorption of purine nucleosides in rats.
Topics: Adenine; Adenosine; Animals; Carbon Radioisotopes; Gastric Absorption; Inosine; Lactobacillus gasseri; Male; Purine Nucleosides; Purines; Rats, Wistar; Species Specificity | 2018 |
Base-pairing probability in the microRNA stem region affects the binding and editing specificity of human A-to-I editing enzymes ADAR1-p110 and ADAR2.
Topics: Adenosine; Adenosine Deaminase; Base Pairing; Deamination; Genome-Wide Association Study; HeLa Cells; Humans; Inosine; Isoenzymes; MicroRNAs; Nucleotide Motifs; Protein Structure, Secondary; RNA Editing; RNA-Binding Proteins | 2018 |
SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates.
Topics: Adenosine; Adenosine Deaminase; Base Sequence; Binding Sites; Brain; Cell Line; Cell Nucleus; HEK293 Cells; Humans; Inosine; RNA Editing; RNA-Binding Proteins; Serine-Arginine Splicing Factors | 2018 |
Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling.
Topics: Adenosine; Humans; Inosine; MicroRNAs; Reference Standards; Reproducibility of Results; RNA Editing; Sequence Analysis, RNA | 2018 |
Organ-wide profiling in mouse reveals high editing levels of Filamin B mRNA in the musculoskeletal system.
Topics: Adenosine; Adenosine Deaminase; Animals; Bone and Bones; Cartilage; Filamins; Humans; Inosine; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Neurons; RNA Editing; RNA-Binding Proteins; RNA, Messenger | 2018 |
RNA editing in bacteria: occurrence, regulation and significance.
Topics: Adenosine; Adenosine Deaminase; Bacterial Toxins; Deamination; Drug Resistance, Bacterial; Inosine; Klebsiella pneumoniae; RNA Editing; RNA, Messenger; RNA, Transfer; Toxin-Antitoxin Systems; Yersinia enterocolitica | 2018 |
The landscape of the A-to-I RNA editome from 462 human genomes.
Topics: Adenosine; Adenosine Deaminase; Computational Biology; Databases, Genetic; Deamination; Genetics, Population; Genome, Human; Humans; Inosine; Quantitative Trait Loci; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Transcriptome | 2018 |
The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs.
Topics: Adenosine; Animals; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cytidine; Cytosine; Helminth Proteins; Inosine; Kinetics; Models, Molecular; Mutation; Nucleosides; Protein Conformation; Protein Isoforms; Purine-Nucleoside Phosphorylase; Schistosoma mansoni; Substrate Specificity | 2018 |
A protein-protein interaction underlies the molecular basis for substrate recognition by an adenosine-to-inosine RNA-editing enzyme.
Topics: Adenosine; Adenosine Deaminase; Animals; Animals, Genetically Modified; Binding, Competitive; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Deamination; Gene Expression Profiling; Inosine; Mutation; Protein Binding; RNA Editing; RNA, Double-Stranded; Substrate Specificity | 2018 |
Proteogenomics of Adenosine-to-Inosine RNA Editing in the Fruit Fly.
Topics: Acyltransferases; Adenosine; Adenosine Deaminase; Amino Acid Sequence; Animals; Base Sequence; Brain; Databases, Protein; Datasets as Topic; Drosophila melanogaster; Drosophila Proteins; Inosine; Insect Proteins; Models, Molecular; Molecular Sequence Annotation; Proteogenomics; Proteome; Qa-SNARE Proteins; RNA Editing; Synaptic Vesicles | 2018 |
Stability of RNA duplexes containing inosine·cytosine pairs.
Topics: Adenosine; Adenosine Deaminase; Base Pairing; Base Sequence; Cytosine; Guanosine; Hydrogen Bonding; Inosine; Kinetics; Nucleic Acid Conformation; Oligoribonucleotides; RNA; RNA-Binding Proteins; Thermodynamics | 2018 |
Inosine induces context-dependent recoding and translational stalling.
Topics: Adenosine; Adenosine Deaminase; Amino Acid Sequence; Animals; Base Sequence; Cell-Free System; Cloning, Molecular; Deamination; Escherichia coli; Gene Expression; Genetic Code; Guanosine; Humans; Inosine; Peptides; Plasmids; Protein Biosynthesis; Rabbits; Recombinant Proteins; Reticulocytes; Ribosomes; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Uracil | 2019 |
Fluorescing Isofunctional Ribonucleosides: Assessing Adenosine Deaminase Activity and Inhibition.
Topics: Adenosine; Adenosine Deaminase; Enzyme Inhibitors; Fluorescence; Guanosine; Inosine; Kinetics | 2019 |
Transcriptome-wide identification of A-to-I RNA editing sites using ICE-seq.
Topics: Adenosine; Animals; DNA, Complementary; Ethanol; Ethylamines; High-Throughput Nucleotide Sequencing; Humans; Inosine; Molecular Sequence Annotation; Nitriles; Poly A; RNA Editing; RNA, Double-Stranded; RNA, Messenger; Transcriptome | 2019 |
Sensitive ADAR editing reporter in cancer cells enables high-throughput screening of small molecule libraries.
Topics: Adenosine; Adenosine Deaminase; Apoptosis; Autoimmune Diseases of the Nervous System; Gene Editing; Genes, Reporter; HeLa Cells; High-Throughput Screening Assays; Humans; Inosine; Interferons; Luciferases; Luminescent Measurements; Nanoparticles; Neoplasms; Nervous System Malformations; RNA-Binding Proteins; Small Molecule Libraries; Transcriptome | 2019 |
Adenosine Deaminase Acting on RNA 1 Associates with Orf Virus OV20.0 and Enhances Viral Replication.
Topics: A549 Cells; Adenosine; Adenosine Deaminase; Animals; Cell Line; Cell Line, Tumor; Ecthyma, Contagious; GTPase-Activating Proteins; HEK293 Cells; Humans; Immunity, Innate; Inosine; Orf virus; Phosphorylation; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Viral; Sheep; Viral Proteins; Virus Replication | 2019 |
Regulation of RNA editing by RNA-binding proteins in human cells.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Autoantigens; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hep G2 Cells; Humans; Inosine; K562 Cells; Lupus Erythematosus, Systemic; Ribonucleoproteins; RNA Editing; RNA-Binding Proteins; RNA, Small Cytoplasmic; Sequence Analysis, RNA; Transcription, Genetic; Transfection | 2019 |
Illuminating spatial A-to-I RNA editing signatures within the
Topics: Adenosine; Amino Acid Sequence; Animals; Brain; Drosophila; Fluorescent Antibody Technique; Inosine; Microscopy, Confocal; Models, Molecular; Neurons; Protein Conformation; RNA Editing; Transcriptome; Voltage-Dependent Anion Channels | 2019 |
EPAI-NC: Enhanced prediction of adenosine to inosine RNA editing sites using nucleotide compositions.
Topics: Adenosine; Area Under Curve; Inosine; Machine Learning; RNA; RNA Editing; ROC Curve; User-Computer Interface | 2019 |
tRNA deamination by ADAT requires substrate-specific recognition mechanisms and can be inhibited by tRFs.
Topics: Adenosine; Adenosine Deaminase; Anticodon; Base Sequence; Deamination; Evolution, Molecular; Gene Expression; Humans; Inosine; Nucleic Acid Conformation; RNA, Transfer, Ala; RNA, Transfer, Arg; Sequence Alignment; Substrate Specificity | 2019 |
FairBase: a comprehensive database of fungal A-to-I RNA editing.
Topics: Adenosine; Databases, Nucleic Acid; Fungi; Inosine; Internet; RNA Editing; User-Computer Interface | 2019 |
CREDO: Highly confident disease-relevant A-to-I RNA-editing discovery in breast cancer.
Topics: Adenosine; Breast Neoplasms; Computational Biology; Databases, Genetic; Exome Sequencing; Female; Humans; Inosine; Kaplan-Meier Estimate; RNA Editing; Web Browser | 2019 |
RNA-Guided Adenosine Deaminases: Advances and Challenges for Therapeutic RNA Editing.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; Point Mutation; RNA; RNA Editing; RNA-Binding Proteins; RNA, Guide, Kinetoplastida; Transcriptome | 2019 |
Increased fermentative adenosine production by gene-targeted Bacillus subtilis mutation.
Topics: Adenosine; Adenosine Monophosphate; Adenylosuccinate Synthase; Bacillus subtilis; Carbon-Nitrogen Ligases; Fermentation; Gene Targeting; Inosine; Inosine Monophosphate; Mutagenesis, Site-Directed; Mutation | 2019 |
The Cancer Editome Atlas: A Resource for Exploratory Analysis of the Adenosine-to-Inosine RNA Editome in Cancer.
Topics: Adenosine; Computational Biology; Datasets as Topic; Humans; Inosine; MicroRNAs; Neoplasms; RNA Editing | 2019 |
Disruption in A-to-I Editing Levels Affects C. elegans Development More Than a Complete Lack of Editing.
Topics: Adenosine; Adenosine Deaminase; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Inosine; Mutation; Phenotype; Proteome; RNA Editing; Transcriptome | 2019 |
Genome-wide identification and analysis of A-to-I RNA editing events in the malignantly transformed cell lines from bronchial epithelial cell line induced by α-particles radiation.
Topics: Adenosine; Alpha Particles; Bronchi; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Epithelial Cells; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Inosine; RNA Editing | 2019 |
Clinical Relevance of Noncoding Adenosine-to-Inosine RNA Editing in Multiple Human Cancers.
Topics: 3' Untranslated Regions; Adenosine; Biomarkers, Tumor; Computational Biology; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inosine; MicroRNAs; Neoplasms; Prognosis; RNA Editing; RNA, Untranslated | 2019 |
A cytosine deaminase for programmable single-base RNA editing.
Topics: Adenosine; Adenosine Deaminase; beta Catenin; Cytidine; Cytosine Deaminase; HEK293 Cells; Humans; Inosine; Protein Domains; Protein Engineering; RNA Editing; RNA-Binding Proteins; Uridine | 2019 |
Increased adenosine-to-inosine RNA editing in rheumatoid arthritis.
Topics: Adenosine; Adenosine Deaminase; Arthritis, Rheumatoid; Female; Gene Expression Regulation; Humans; Inosine; Leukocytes, Mononuclear; Male; Middle Aged; Protein Isoforms; RNA; RNA Editing; RNA-Binding Proteins; Transcriptome; Up-Regulation | 2020 |
A-to-I RNA editing contributes to the persistence of predicted damaging mutations in populations.
Topics: Adenosine; Gene Frequency; Humans; Inosine; Mutation, Missense; RNA; RNA Editing | 2019 |
Identification of Adenosine-to-Inosine RNA Editing with Acrylonitrile Reagents.
Topics: Acrylonitrile; Adenosine; Biotinylation; Inosine; Nucleic Acid Conformation; RNA; RNA Editing | 2019 |
Adenosine-to-Inosine RNA Editing in Mouse and Human Brain Proteomes.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; Animals; Brain; Cells, Cultured; Coatomer Protein; Humans; Inosine; Mice; Proteome; Proteomics; RNA Editing | 2019 |
A robust model for quantitative prediction of the silencing efficacy of wild-type and A-to-I edited miRNAs.
Topics: Adenosine; Algorithms; Amino Acid Substitution; Inosine; Machine Learning; MicroRNAs; Models, Biological; Nucleic Acid Conformation; RNA Editing; RNA Interference; RNA Stability; RNA, Messenger; Thermodynamics | 2020 |
Genome-wide quantification of ADAR adenosine-to-inosine RNA editing activity.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Animals; Base Sequence; Humans; Inosine; Mice; RNA Editing; RNA-Binding Proteins | 2019 |
The preponderance of nonsynonymous A-to-I RNA editing in coleoids is nonadaptive.
Topics: Adaptation, Biological; Adenosine; Animals; Cephalopoda; Inosine; RNA Editing; Transcriptome | 2019 |
Cell death following the loss of ADAR1 mediated A-to-I RNA editing is not effected by the intrinsic apoptosis pathway.
Topics: Adenosine; Adenosine Deaminase; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Female; Inosine; Male; Mice, Inbred C57BL; RNA Editing; Signal Transduction | 2019 |
Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation.
Topics: Adenosine; Animals; Brain; Inosine; Mice; RNA Editing; Sequence Analysis, RNA; Spatio-Temporal Analysis | 2020 |
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma.
Topics: Adenosine; Animals; Antineoplastic Agents; Carcinogenesis; Cell Line; Deoxyribonuclease (Pyrimidine Dimer); Gene Expression; Humans; Inosine; Liver; Liver Neoplasms, Experimental; Mice, Knockout; RNA Editing; RNA, Transfer; Sequence Analysis, RNA; Sorafenib | 2020 |
A-to-I RNA Editing Uncovers Hidden Signals of Adaptive Genome Evolution in Animals.
Topics: Adenosine; Animals; Drosophila melanogaster; Evolution, Molecular; Genome; Humans; Inosine; RNA Editing | 2020 |
Opposing Effects of Adenosine and Inosine in Human Subcutaneous Fibroblasts May Be Regulated by Third Party ADA Cell Providers.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Cyclic AMP; Fibroblasts; GPI-Linked Proteins; Humans; Inosine | 2020 |
Spatially regulated editing of genetic information within a neuron.
Topics: Adenosine; Adenosine Deaminase; Animals; Axons; Cytoplasm; Decapodiformes; HEK293 Cells; Humans; Inosine; Neurons; Potassium Channels, Voltage-Gated; RNA Editing; Synapses | 2020 |
irCLASH reveals RNA substrates recognized by human ADARs.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; Nucleic Acid Conformation; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Messenger; Transcriptome | 2020 |
The A-to-I RNA Editing Enzyme
Topics: Adenosine; Adenosine Deaminase; Animals; Apoptosis; Cell Proliferation; Cell Survival; Crosses, Genetic; Deamination; Gene Deletion; Heart; Inosine; Mice; Myocytes, Cardiac; RNA Editing | 2020 |
Sense-antisense miRNA pairs constitute an elaborate reciprocal regulatory circuit.
Topics: Adenosine; Gene Expression Regulation; Humans; Inosine; MicroRNAs; RNA Editing; RNA-Seq; RNA, Antisense | 2020 |
Chemical Profiling of A-to-I RNA Editing Using a Click-Compatible Phenylacrylamide.
Topics: Acrylamide; Adenosine; Click Chemistry; Inosine; RNA; RNA Editing | 2020 |
EndoVIPER-seq for Improved Detection of A-to-I Editing Sites in Cellular RNA.
Topics: Adenosine; High-Throughput Nucleotide Sequencing; Inosine; RNA; RNA Editing | 2020 |
Ascertaining the activity and inhibition of adenosine deaminase via fluorescence-based assays.
Topics: Adenosine; Adenosine Deaminase; Biological Assay; Inosine | 2020 |
Adaptation of codon usage to tRNA I34 modification controls translation kinetics and proteome landscape.
Topics: Adenosine; Adenosine Deaminase; Anticodon; Codon Usage; Computational Biology; Fungal Proteins; Inosine; Neurospora crassa; Peptide Chain Elongation, Translational; Proteome; Ribosomes; RNA, Transfer, Arg | 2020 |
Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression.
Topics: Adenosine; Adenosine Deaminase; Apoptosis Regulatory Proteins; Humans; Inosine; Neoplasms; RNA; RNA-Binding Proteins | 2020 |
ADAR-deficiency perturbs the global splicing landscape in mouse tissues.
Topics: Adenosine; Adenosine Deaminase; Animals; Inosine; Mice; Mice, Knockout; RNA Editing; RNA Processing, Post-Transcriptional; RNA Splicing; RNA-Binding Proteins; RNA, Circular; RNA, Messenger; Sequence Analysis, RNA | 2020 |
Discovering RNA Editing Events in Fungi.
Topics: Adenosine; Computational Biology; Fungi; Genome, Fungal; High-Throughput Nucleotide Sequencing; Inosine; RNA Editing; RNA, Fungal; Software | 2021 |
Adenosine-to-Inosine RNA Editing Enzyme ADAR and microRNAs.
Topics: Adenosine; Adenosine Deaminase; Humans; Inosine; MicroRNAs; RNA Editing; RNA Interference; RNA-Binding Proteins | 2021 |
Quantitative Analysis of Adenosine-to-Inosine RNA Editing.
Topics: Adenosine; DNA, Complementary; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Inosine; RNA Editing; Transcriptome | 2021 |
Discovering A-to-I RNA Editing Through Chemical Methodology "ICE-seq".
Topics: Adenosine; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Inosine; RNA Editing; Transcriptome | 2021 |
RNA Editing in Human and Mouse Tissues.
Topics: Adenosine; Animals; Computational Biology; Genome; High-Throughput Nucleotide Sequencing; Humans; Inosine; Mice; RNA; RNA Editing; Transcriptome | 2021 |
Detection of A-to-I Hyper-edited RNA Sequences.
Topics: Adenosine; Animals; Base Sequence; Humans; Inosine; RNA Editing; RNA, Double-Stranded; Sequence Analysis, RNA | 2021 |
MicroRNA Editing Detection and Function: A Combined In Silico and Experimental Approach for the Identification and Validation of Putative Oncogenic Targets.
Topics: Adenosine; Animals; Carcinogenesis; Computational Biology; Humans; Inosine; MicroRNAs; Neoplasms; Oncogenes; RNA Editing; Sequence Analysis, DNA; Validation Studies as Topic | 2021 |
Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder.
Topics: Active Transport, Cell Nucleus; Adenosine; Adenosine Deaminase; Adolescent; Binding Sites; Cells, Cultured; Child; Child, Preschool; Codon, Terminator; Exome Sequencing; Female; Genetic Predisposition to Disease; Humans; Inosine; Intellectual Disability; Male; Mutation, Missense; Pedigree; Protein Domains; RNA-Binding Proteins; RNA, Transfer | 2020 |
A-to-I RNA editing in bacteria increases pathogenicity and tolerance to oxidative stress.
Topics: Adenosine; Bacterial Proteins; Hydrogen Peroxide; Inosine; Oxidative Stress; Plant Diseases; RNA Editing; Virulence; Xanthomonas | 2020 |
Adenosine Metabolism in the Cerebral Cortex from Several Mice Models during Aging.
Topics: Adenosine; Aging; Alzheimer Disease; Animals; Cellular Senescence; Cerebral Cortex; Disease Models, Animal; Hippocampus; Humans; Inosine; Mice; Phosphorylation; Xanthine | 2020 |
Adenosine-to-Inosine RNA Editing of Alu Double-Stranded (ds)RNAs Is Markedly Decreased in Multiple Sclerosis and Unedited Alu dsRNAs Are Potent Activators of Proinflammatory Transcriptional Responses.
Topics: Adenosine; Alu Elements; Datasets as Topic; DEAD Box Protein 58; HEK293 Cells; Humans; Inflammation; Inosine; Interferons; Multiple Sclerosis, Relapsing-Remitting; NF-kappa B; Receptors, Immunologic; RNA Editing; RNA-Seq; RNA, Double-Stranded; Signal Transduction; THP-1 Cells; Toll-Like Receptor 3; Transcriptional Activation; Whole Genome Sequencing | 2020 |
Experimental and theoretical rationalization for the base pairing abilities of inosine, guanosine, adenosine, and their corresponding 8-oxo-7,8-dihydropurine, and 8-bromopurine analogues within A-form duplexes of RNA.
Topics: Adenosine; Base Pairing; Guanine; Guanosine; Hydrogen Bonding; Inosine; Models, Chemical; Models, Genetic; Molecular Structure; Nucleic Acid Conformation; RNA; Thermodynamics | 2020 |
Human A-to-I RNA editing SNP loci are enriched in GWAS signals for autoimmune diseases and under balancing selection.
Topics: Adenosine; Adenosine Deaminase; Alleles; Autoimmune Diseases; Gene Frequency; Genome-Wide Association Study; Genomics; Humans; Inosine; Polymorphism, Single Nucleotide; RNA Editing; RNA, Double-Stranded; Transcriptome | 2020 |
Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development.
Topics: Adenosine; Adenosine Deaminase; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Inosine; RNA Editing | 2021 |
ADeditome provides the genomic landscape of A-to-I RNA editing in Alzheimer's disease.
Topics: Adenosine; Alternative Splicing; Alzheimer Disease; Amnesia; Brain; Brain Mapping; Databases, Genetic; Gene Ontology; Humans; Inosine; MicroRNAs; Molecular Sequence Annotation; Nerve Tissue Proteins; Receptors, AMPA; RNA Editing; Transcriptome | 2021 |
Identification and Analysis of RNA Editing Events in Ovarian Serous Cystadenoma Using RNA-seq Data.
Topics: Adenosine; Cystadenoma, Serous; Female; Genome-Wide Association Study; Humans; Inosine; MicroRNAs; Ovarian Neoplasms; RNA Editing; RNA-Seq; RNA, Messenger | 2021 |
Elevated blood purine levels as a biomarker of seizures and epilepsy.
Topics: Adenosine; Adult; Animals; Biomarkers; Case-Control Studies; Epilepsy; Humans; Hypoxanthine; Inosine; Male; Mice; Mice, Inbred C57BL; Middle Aged; Point-of-Care Testing; Purines; Seizures; Severity of Illness Index; Status Epilepticus; Xanthine; Young Adult | 2021 |
Cutting Edge: Reduced Adenosine-to-Inosine Editing of Endogenous Alu RNAs in Severe COVID-19 Disease.
Topics: Adenosine; Alu Elements; COVID-19; Dendritic Cells; Genome, Human; Humans; Inosine; Interferon Regulatory Factors; NF-kappa B; RNA Editing; RNA-Seq; RNA, Double-Stranded; SARS-CoV-2; Severity of Illness Index; Signal Transduction | 2021 |
Systematic identification of A-to-I RNA editing in zebrafish development and adult organs.
Topics: Adenosine; Animals; Gene Expression Regulation, Developmental; Genetic Code; Inosine; RNA Editing; Zebrafish | 2021 |
Deciphering the principles of the RNA editing code via large-scale systematic probing.
Topics: A549 Cells; Adenosine; Adenosine Deaminase; Animals; Base Pairing; HEK293 Cells; Humans; Inosine; MCF-7 Cells; Mice; NIH 3T3 Cells; Nucleic Acid Conformation; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded | 2021 |
Radical Dehalogenation and Purine Nucleoside Phosphorylase
Topics: Adenosine; Biocatalysis; Deoxyadenosines; Deuterium Oxide; Escherichia coli; Escherichia coli Proteins; Hydrolysis; Inosine; Purine-Nucleoside Phosphorylase; Substrate Specificity | 2021 |
Direct Immunodetection of Global A-to-I RNA Editing Activity with a Chemiluminescent Bioassay.
Topics: Adenosine; Humans; Inosine; Luminescent Measurements; RNA; RNA Editing | 2021 |
The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination.
Topics: Adenosine; Adenosine Deaminase; Animals; Catalytic Domain; Cell Line, Tumor; Cell Movement; Crystallography, X-Ray; Ferredoxins; Inosine; Mice; Models, Molecular; Mutation; Neurons; Protein Domains; RNA, Transfer | 2021 |
A porcine brain-wide RNA editing landscape.
Topics: Adenosine; Animals; Brain; Female; Gene Expression Regulation; Inosine; Male; RNA Editing; Swine | 2021 |
Developing PspCas13b-based enhanced RESCUE system, eRESCUE, with efficient RNA base editing.
Topics: Adenosine; Adenosine Deaminase; CRISPR-Cas Systems; Cytidine; Genetic Diseases, Inborn; HEK293 Cells; Humans; I-kappa B Kinase; Inosine; RNA; RNA Editing; RNA-Binding Proteins; Uridine | 2021 |
Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Deaminase; Animals; Autoimmune Diseases of the Nervous System; Inosine; Interferon Type I; Mice; Mutation; Nervous System Malformations; RNA Editing; RNA, Double-Stranded | 2021 |
Adenosine-to-inosine RNA editing contributes to type I interferon responses in systemic sclerosis.
Topics: Adenosine; Adenosine Deaminase; Animals; Endothelial Cells; Humans; Inosine; Interferon Type I; Leukocytes, Mononuclear; RNA; RNA Editing; RNA-Binding Proteins; Scleroderma, Systemic | 2021 |
Conservation of A-to-I RNA editing in bowhead whale and pig.
Topics: Adenosine; Animals; Bowhead Whale; DNA Glycosylases; Inosine; Peptide Elongation Factor 1; RNA Editing; RNA, Messenger; Shab Potassium Channels; Swine; Zinc Finger Protein GLI1 | 2021 |
Quantification of allantoin and other metabolites of the purine degradation pathway in human plasma samples using a newly developed HILIC-LC-MS/MS method.
Topics: Adenosine; Allantoin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Hypoxanthines; Inosine; Purines; Reproducibility of Results; Tandem Mass Spectrometry | 2022 |
Differential Analysis of A-to-I mRNA Edited Sites in Parkinson's Disease.
Topics: Adenosine; Aged; Humans; Inosine; Male; Mitochondria; Parkinson Disease; Prefrontal Cortex; Proteome; RNA; RNA Editing; RNA, Messenger; Sequence Analysis, RNA; Transcriptome | 2021 |
Detection of A-to-I RNA Editing in SARS-COV-2.
Topics: Adenosine; Adenosine Deaminase; Animals; Cell Line, Tumor; Chlorocebus aethiops; COVID-19; DEAD Box Protein 58; Deamination; Epithelial Cells; Genome, Viral; Host-Pathogen Interactions; Humans; Immunity, Innate; Inosine; Interferon-beta; Interferon-Induced Helicase, IFIH1; Receptors, Immunologic; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Viral; SARS-CoV-2; Transcriptome; Vero Cells | 2021 |
Alu RNA Structural Features Modulate Immune Cell Activation and A-to-I Editing of Alu RNAs Is Diminished in Human Inflammatory Bowel Disease.
Topics: Adenosine; Alu Elements; COVID-19; Humans; Inflammatory Bowel Diseases; Inosine; RNA, Double-Stranded; SARS-CoV-2 | 2022 |
Landscape of adenosine-to-inosine RNA recoding across human tissues.
Topics: Adenosine; Animals; Genome; Humans; Inosine; Mammals; RNA; RNA Editing | 2022 |
The E3 ubiquitin ligase SMURF2 stabilizes RNA editase ADAR1p110 and promotes its adenosine-to-inosine (A-to-I) editing function.
Topics: Adenosine; Animals; Inosine; Mammals; Mice; Proteins; RNA; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2022 |
REIA: A database for cancer A-to-I RNA editing with interactive analysis.
Topics: Adenosine; Humans; Inosine; Neoplasms; RNA; RNA Editing | 2022 |
Systematically Modulating Aptamer Affinity and Specificity by Guanosine-to-Inosine Substitution.
Topics: Adenosine; Aptamers, Nucleotide; Guanosine; Inosine | 2022 |
Spatial epitranscriptomics reveals A-to-I editome specific to cancer stem cell microniches.
Topics: Adenosine; Adenosine Deaminase; Humans; Inosine; Neoplastic Stem Cells; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2022 |
Single-Base Resolution Detection of Adenosine-to-Inosine RNA Editing by Endonuclease-Mediated Sequencing.
Topics: Adenosine; Endonucleases; Humans; Inosine; RNA; RNA Editing | 2022 |
Direct identification of A-to-I editing sites with nanopore native RNA sequencing.
Topics: Adenosine; Animals; Inosine; Mice; Nanopores; RNA; RNA Editing; Sequence Analysis, RNA | 2022 |
Quantitative analysis of 20 purine and pyrimidine metabolites by HILIC-MS/MS in the serum and hippocampus of depressed mice.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Chromatography, High Pressure Liquid; Hippocampus; Hypoxanthines; Inosine; Mice; Purines; Pyrimidines; Tandem Mass Spectrometry | 2022 |
Metabolic reprogramming under hypoxic storage preserves faster oxygen unloading from stored red blood cells.
Topics: Adenosine; Blood Preservation; Erythrocytes; Hemoglobins; Humans; Hypoxia; Inosine; Oxygen; Phosphates; Pyruvates | 2022 |
RNA editing enzyme ADAR1 controls miR-381-3p-mediated expression of multidrug resistance protein MRP4 via regulation of circRNA in human renal cells.
Topics: Adenosine; Adenosine Deaminase; Drug Resistance, Multiple; Humans; Inosine; Kidney; MicroRNAs; Multidrug Resistance-Associated Proteins; RNA Editing; RNA-Binding Proteins; RNA, Circular | 2022 |
RNA binding by ADAR3 inhibits adenosine-to-inosine editing and promotes expression of immune response protein MAVS.
Topics: 3' Untranslated Regions; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Deaminase; Glioblastoma; Humans; Immunity, Innate; Inosine; Protein Binding; RNA-Binding Proteins; RNA, Double-Stranded | 2022 |
ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Deaminase; Animals; Apoptosis; Autoimmune Diseases of the Nervous System; Caspase 8; Humans; Inflammation; Inosine; Intestines; Mice; Necroptosis; Nervous System Malformations; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded; Skin | 2022 |
RNA editing underlies genetic risk of common inflammatory diseases.
Topics: Adenosine; Adenosine Deaminase; Alu Elements; Autoimmune Diseases; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Immune System Diseases; Immunity, Innate; Inflammation; Inosine; Interferon-Induced Helicase, IFIH1; Interferons; Quantitative Trait Loci; RNA Editing; RNA-Binding Proteins; RNA, Double-Stranded | 2022 |
RNA-Editing Enzyme ADAR1 p150 Isoform Is Critical for Germinal Center B Cell Response.
Topics: Adenosine; Adenosine Deaminase; Animals; B-Lymphocytes; Germinal Center; Inosine; Interferon-Induced Helicase, IFIH1; Mammals; Mice; Protein Isoforms; Protein Kinases; RNA-Binding Proteins; RNA, Double-Stranded | 2022 |
ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7.
Topics: Adenosine; Adenosine Deaminase; Animals; Heart Failure; Inosine; Interferon Regulatory Factor-7; Interferon-Induced Helicase, IFIH1; Interferons; Mice; Mice, Mutant Strains; NF-kappa B; RNA | 2022 |
Pan-Cancer Analysis of Canonical and Modified miRNAs Enhances the Resolution of the Functional miRNAome in Cancer.
Topics: Adenosine; Adult; Biomarkers, Tumor; Child; Humans; Inosine; MicroRNAs; Neoplasms | 2022 |
A high-throughput approach to predict A-to-I effects on RNA structure indicates a change of double-stranded content in noncoding RNAs.
Topics: Adenosine; Humans; Inosine; RNA, Long Noncoding; RNA, Messenger; RNA, Untranslated | 2023 |
Uncovering
Topics: Adenosine; Adenosine Deaminase; Animals; Inosine; Nucleotides; RNA; RNA Editing | 2022 |
U-to-C RNA editing by synthetic PPR-DYW proteins in bacteria and human culture cells.
Topics: Adenosine; Bacteria; Cytidine; Guanosine; Humans; Inosine; Nucleotides; Plant Proteins; RNA; RNA Editing; Uridine | 2022 |
RNA modification writer expression profiles predict clinical outcomes and guide neoadjuvant immunotherapy in non-small cell lung cancer.
Topics: Adenosine; Carcinoma, Non-Small-Cell Lung; Humans; Immune Checkpoint Inhibitors; Immunologic Factors; Immunotherapy; Inosine; Lung Neoplasms; Neoadjuvant Therapy; Prognosis; RNA; Tumor Microenvironment | 2022 |
Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish.
Topics: Adenosine; Animals; Immunity, Innate; Inosine; Mammals; RNA; RNA-Binding Proteins; Zebrafish | 2022 |
The impact of inosine on hippocampal synaptic transmission and plasticity involves the release of adenosine through equilibrative nucleoside transporters rather than the direct activation of adenosine receptors.
Topics: Adenosine; Animals; Hippocampus; Humans; Inosine; Nucleosides; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A1; Synaptic Transmission | 2023 |
Four types of RNA modification writers predict the prognosis of prostate cancer.
Topics: Adenosine; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Inosine; Male; Prognosis; Prostatic Neoplasms; RNA | 2022 |
Pathogenic variant c.1052T>A (p.Leu351Gln) in adenosine deaminase 2 impairs secretion and elevates type I IFN responsive gene expression.
Topics: Adenosine; Adenosine Deaminase; Animals; Asparagine; Gene Expression; Inosine; Intercellular Signaling Peptides and Proteins; Interferon Type I; Mammals; Mutation | 2022 |
Immunosuppressive lncRNA LINC00624 promotes tumor progression and therapy resistance through ADAR1 stabilization.
Topics: Adenosine; Adenosine Deaminase; Animals; beta-Transducin Repeat-Containing Proteins; Humans; Immune Checkpoint Inhibitors; Inosine; Interferon Type I; Mice; Oligonucleotides, Antisense; Recombinant Proteins; RNA-Binding Proteins; RNA, Double-Stranded; RNA, Long Noncoding | 2022 |
Suppressed renoprotective purines in COVID-19 patients with acute kidney injury.
Topics: Acute Kidney Injury; Adenosine; Adenosine Monophosphate; Animals; COVID-19; Guanosine; Guanosine Monophosphate; Inosine; Purines | 2022 |
Unveiling the functional and evolutionary landscape of RNA editing in chicken using genomics and transcriptomics.
Topics: Adenosine; Adenosine Deaminase; Animals; Chickens; Genomics; Humans; Inosine; RNA; RNA Editing; Transcriptome | 2022 |
ADAR regulates APOL1 via A-to-I RNA editing by inhibition of MDA5 activation in a paradoxical biological circuit.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; Apolipoprotein L1; Humans; Inosine; Interferon Type I; Interferon-gamma; Interferon-Induced Helicase, IFIH1; Mice; RNA Editing; RNA, Double-Stranded; RNA, Messenger | 2022 |
Spatiotemporal and genetic regulation of A-to-I editing throughout human brain development.
Topics: 3' Untranslated Regions; Adenosine; Adenosine Deaminase; Animals; Brain; Humans; Inosine; Mice; Primates; RNA Editing | 2022 |
Somatic A-to-I RNA-edited RHOA isoform 2 specific-R176G mutation promotes tumor progression in lung adenocarcinoma.
Topics: Adenocarcinoma of Lung; Adenosine; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Guanosine Triphosphate; Humans; Inosine; Lung Neoplasms; Mutation; Protein Isoforms; Proteomics; rhoA GTP-Binding Protein; RNA | 2023 |
Profiling RNA Editing in Single Cells.
Topics: Adenosine; Adenosine Deaminase; Humans; Inosine; RNA; RNA Editing; RNA, Double-Stranded | 2023 |
Altered RNA Editing in Atopic Dermatitis Highlights the Role of Double-Stranded RNA for Immune Surveillance.
Topics: Adenosine; Adenosine Deaminase; Dermatitis, Atopic; Humans; Inosine; RNA Editing; RNA, Double-Stranded | 2023 |
RNA editing of microtubule-associated protein tau circular RNAs promotes their translation and tau tangle formation.
Topics: Adenosine; Codon, Initiator; Humans; Inosine; RNA; RNA Editing; RNA, Circular; tau Proteins; Tauopathies | 2022 |
Increasing inosine/decreasing ENT1: promising strategies for anti-obesity therapy.
Topics: Adenosine; Equilibrative Nucleoside Transporter 1; Inosine | 2023 |
The Profiles and Functions of RNA Editing Sites Associated with High-Altitude Adaptation in Goats.
Topics: Adenosine; Altitude; Animals; Goats; Inosine; Mutation; RNA; RNA Editing | 2023 |
Library Screening Reveals Sequence Motifs That Enable ADAR2 Editing at Recalcitrant Sites.
Topics: Adenosine; Adenosine Deaminase; Base Pairing; Hydrolysis; Inosine; RNA | 2023 |
ATTIC is an integrated approach for predicting A-to-I RNA editing sites in three species.
Topics: Adenosine; Animals; Drosophila melanogaster; Humans; Inosine; Mice; RNA; RNA Editing | 2023 |
Massive Proteogenomic Reanalysis of Publicly Available Proteomic Datasets of Human Tissues in Search for Protein Recoding via Adenosine-to-Inosine RNA Editing.
Topics: Adenosine; Animals; Chromatography, Liquid; Humans; Inosine; Mice; Proteogenomics; Proteome; Proteomics; RNA; RNA Editing; Tandem Mass Spectrometry | 2023 |
Development and evaluation of an adenosine-to-inosine RNA editing-based prognostic model for survival prediction of bladder cancer patients.
Topics: Adenosine; Humans; Inosine; Prognosis; RNA Editing; Urinary Bladder Neoplasms | 2023 |
Probiotic-Derived Ecto-5'-Nucleotidase Produces Anti-Inflammatory Adenosine Metabolites in Treg-Deficient Scurfy Mice.
Topics: 5'-Nucleotidase; Adenosine; Animals; Anti-Inflammatory Agents; CD8-Positive T-Lymphocytes; Humans; Inosine; Mice; T-Lymphocytes, Regulatory | 2023 |
Amphioxus adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U and A-to-I deamination of DNA.
Topics: Adenosine; Adenosine Deaminase; Animals; Deamination; DNA; Escherichia coli; Inosine; Lancelets; RNA, Transfer | 2023 |
Topics: Adenosine; Adenosine Deaminase; Anticodon; Bacillus subtilis; Inosine; Magnoliopsida; RNA, Transfer; RNA, Transfer, Arg | 2023 |
Components of the Nucleotide Salvage Pathway Increase Frog Virus 3 (FV3) Replication.
Topics: Adenine; Adenosine; Animals; Inosine; Nucleotides; Purines; Ranavirus | 2023 |
Genome-Wide Analysis on Driver and Passenger RNA Editing Sites Suggests an Underestimation of Adaptive Signals in Insects.
Topics: Adenosine; Animals; Drosophila melanogaster; Genome; Inosine; RNA; RNA Editing | 2023 |
Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections.
Topics: Adenosine; Adenosine Deaminase; Animals; Cytomegalovirus Infections; Humans; Inosine; Mice; RNA Editing; Zika Virus; Zika Virus Infection | 2023 |