adenosine and apyrase
adenosine has been researched along with apyrase in 224 studies
Research
Studies (224)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (5.80) | 18.7374 |
| 1990's | 14 (6.25) | 18.2507 |
| 2000's | 46 (20.54) | 29.6817 |
| 2010's | 113 (50.45) | 24.3611 |
| 2020's | 38 (16.96) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Lewis, GP; Lieberman, GE; Peters, TJ | 1 |
| Rosenberg, JC; Sell, T | 1 |
| Anderson, MW; Crutchley, DJ; Eling, TE | 1 |
| Fujitani, B; Shimizu, M; Tsuboi, T; Yoshida, K | 1 |
| Nunn, B | 1 |
| Hoak, JC; Wu, KK | 1 |
| Ts'ao, C | 1 |
| Belzer, I; Friedberg, I; Huang, NN; Lane, E; Lustig, KD; Weisman, GA | 1 |
| Altman, R; Scazziota, A | 1 |
| Emms, H; Lewis, GP | 1 |
| Hawiger, J; Sakon, M | 1 |
| Hallam, TJ; Scrutton, MC; Wallis, RB | 1 |
| Culic, O; Lemmens, R; Teuchy, H; Vanduffel, L | 1 |
| Barankiewicz, J; Colmerauer, E; Firestein, GS; Jimenez, R; Uyesaka, J | 1 |
| Dias, RD; Frassetto, SS; Sarkis, JJ | 1 |
| Lind, SE; Vasconcellos, CA | 1 |
| Beaudoin, AR; Côté, YP; Sévigny, J | 1 |
| Gómez de Aranda, I; Martí, E; Solsona, C | 1 |
| Meghji, P; Pearson, JD; Slakey, LL | 1 |
| Beaudoin, AR; Grondin, G; Levesque, FP; Sévigny, J | 1 |
| Chang, YL; Hsu, FL; Kang, YF; Ko, FN; Teng, CM; Yang, SC | 1 |
| Beaudoin, AR; Grondin, G; Picher, M; Sévigny, J | 1 |
| Mezzasoma, I; Minelli, A; Moroni, M; Trinari, D | 1 |
| Ferreira, ST; Torres, CR; Vasconcelos, EG; Verjovski-Almeida, S | 1 |
| Beaudoin, AR; Boyer, JL; Chapal, J; Chulkin, A; Fischer, B; Gendron, FP; Harden, KT; Hillaire-Buys, D; Petit, P | 1 |
| De Jonge, HR; Tilly, BC; Van der Wijk, T | 1 |
| Garcia Soriano, F; Seguro, AC; Tadeu Velasco, I | 1 |
| Csizmadia, E; Lemmens, R; Robson, SC; Sévigny, J; Smith, RN; Waelkens, E | 1 |
| Dudler, R; Lloyd, A; Rajagopal, A; Roux, SJ; Thomas, C; Windsor, B | 1 |
| Henttinen, T; Jalkanen, S; Yegutkin, GG | 1 |
| Battastini, AM; Berti, SL; Bonan, CD; da Silva, FL; Sarkis, JJ; Wannmacher, CM | 1 |
| Kimelberg, HK; Mongin, AA | 1 |
| Adarmes, H; García, L; González, E; Jiménez, PA; Valenzuela, MA | 1 |
| Flores-Herrera, O; García-Pérez, C; Martínez, F; Milán, R; Uribe, A | 1 |
| Dombrowski, KE; Gewirtz, AT; Kapp, JA; Ke, Y; Langston, HP | 1 |
| Amaral, O; Battastini, AM; Bonan, CD; Bruno, AN; Coitinho, A; Oses, JP; Sarkis, JJ | 1 |
| Colgan, SP; Eltzschig, HK; Enjyoji, K; Furuta, GT; Ibla, JC; Jacobson, KA; Leonard, MO; Robson, SC | 1 |
| COHN, M; MEEK, GA | 1 |
| Enjyoji, K; Guckelberger, O; Imai, M; Kaczmarek, E; Kruskal, JB; Robson, SC; Sévigny, J; Sun, XF | 1 |
| D'Souza-Ault, M; Faudry, E; Felix, CR; Kieffer, S; Lozzi, SP; Ricart, CA; Santana, JM; Sousa, MV; Teixeira, AR; Vernet, T | 1 |
| Campbell, DJ; Cowan, PJ; d'Apice, AJ; Dwyer, KM; Fisicaro, N; Gock, H; Kaczmarek, E; Murray-Segal, LJ; Mysore, TB; Nandurkar, HH; Robson, SC | 1 |
| Colgan, SP; Cotta, RJ; Eltzschig, HK; Ibla, JC; Karhausen, J; Robson, SC; Thompson, LF | 1 |
| Casali, EA; Lara, DR; Leke, R; Oses, JP; Portela, LV; Sarkis, JJ; Schmidt, AP; Souza, DO; Wofchuk, S | 1 |
| Komoszyński, M; Kukulski, F; Sévigny, J | 1 |
| Newman, EA | 1 |
| Ahmad, A; Ahmad, S; Allen, CB; Manzer, R; Mason, RJ; McConville, G; Schneider, BK; White, CW | 1 |
| Böhmer, AE; Nejar Bruno, A; Pochmann, D; Sarkis, JJ | 1 |
| Amrani, M; Chester, AH; Osman, L; Smolenski, RT; Yacoub, MH | 1 |
| Bernardo, AA; Coutinho-Silva, R; de Souza, AL; Meyer-Fernandes, JR; Persechini, PM; Pinto-Silva, FE; Rumjanek, VM | 1 |
| Abdallah, Y; Aslam, M; Gündüz, D; Härtel, FV; Kasseckert, SA; Noll, T; Piper, HM; Schäfer, C; Schäfer, M | 1 |
| Ecke, D; Fischer, B; Lévesque, SA; Munkonda, MN; Reiser, G; Sévigny, J; Sharon, E | 1 |
| Gao, ZG; Jacobson, KA; Mamedova, LK | 1 |
| Boengler, K; Colgan, SP; Eckle, T; Eltzschig, HK; Karcher, C; Küper, N; Mager, A; Robson, SC; Schulz, R; Weissmüller, T | 1 |
| Linden, J | 1 |
| Eckle, T; Eltzschig, HK; Grenz, A; Hermes, M; Huang, DY; Klingel, K; Müller, CE; Osswald, H; Robson, SC; Zhang, H | 1 |
| Chen, JF; Deaglio, S; Dwyer, KM; Enjyoji, K; Erat, A; Friedman, D; Gao, W; Kuchroo, VK; Linden, J; Oukka, M; Robson, SC; Strom, TB; Usheva, A | 1 |
| Eckle, T; Eltzschig, HK; Füllbier, L; Ibla, J; Khoury, J; Mittelbronn, M; Rosenberger, P; Wehrmann, M | 1 |
| Eckle, T; Eltzschig, HK; Faigle, M; Grenz, A; Hart, ML; Köhler, D; Laucher, S; Mittelbronn, M; Müller, CE; Robson, SC | 1 |
| Ali, EM | 1 |
| Bringmann, A; Hollborn, M; Iandiev, I; Pannicke, T; Reichenbach, A; Wiedemann, P; Wurm, A; Zimmermann, H | 1 |
| Beldi, G; Chen, Y; Corriden, R; Inoue, Y; Insel, PA; Junger, WG; Robson, SC | 1 |
| Esparza-Perusquía, M; Flores-Herrera, O; Gómez-Concha, C; Guevara-Flores, A; Juárez, O; Martínez, F; Mendoza-Hernández, G; Olvera-Sánchez, S; Pardo, JP | 1 |
| Fernie, AR; Geigenberger, P; Grosman, L; Riewe, D; Wucke, C; Zauber, H | 1 |
| Bonan, CD; Morsch, VM; Schetinger, MR; Wyse, AT | 1 |
| Eltzschig, HK; Ngamsri, KC; Reutershan, J; Stark, S; Vollmer, I; Wagner, R | 1 |
| Cowan, PJ; Crikis, S; d'Apice, AJ; Dwyer, KM; Lee, EK; Lu, B; Rajakumar, SV; Robson, SC | 1 |
| Alam, MS; Crowe, SE; Das, S; Ernst, PB; Kurtz, CC; Linden, J; Reuter, BK; Rowlett, RM; Wiznerowicz, E | 1 |
| Cronstein, BN; Enk, AH; Mahnke, K; Oliver, SJ; Ring, S | 1 |
| Cárdenas, A; Enjyoji, K; Robson, SC; Sun, X; Wu, Y | 1 |
| Bjelobaba, I; Lavrnja, I; Mostarica-Stojkovic, M; Nedeljkovic, N; Pekovic, S; Stojiljkovic, M; Stosic-Grujicic, S | 1 |
| Enk, AH; Johnson, TS; Karakhanova, S; Mahnke, K; Näher, H; Schmitt, S | 1 |
| Czystowska, M; Gorelik, E; Hilldorfer, B; Jackson, EK; Lang, S; Mandapathil, M; Ren, J; Szajnik, M; Szczepanski, MJ; Whiteside, TL | 1 |
| Chaimovitz, C; Czeiger, D; Douvdevani, A; Naamani, O; Nakav, S; Shaked, G; Zlotnik, M | 1 |
| Bernstein, SH; Burack, WR; Cochran, MR; Hilchey, SP; Hyrien, O; Kobie, JJ; Mosmann, TR; Quataert, SA; Secor-Socha, S; Wang, JC | 1 |
| Costelloe, L; Fletcher, JM; Kinsella, K; Lonergan, R; Mills, KH; Moran, B; O'Farrelly, C; Tubridy, N | 1 |
| Gorelik, E; Jackson, EK; Johnson, JT; Lang, S; Mandapathil, M; Ren, J; Szajnik, M; Szczepanski, MJ; Whiteside, TL | 1 |
| Alviano, CS; Alviano, DS; Axelband, F; Cesar, GV; Cosentino-Gomes, D; Fernandes Sampaio, ME; Kiffer-Moreira, T; Meyer-Fernandes, JR; Nimrichter, L; Rodrigues, ML; Vieyra, A | 1 |
| Cowan, PJ; Crikis, S; D'Apice, AJ; Dwyer, KM; Lu, B; Murray-Segal, LM; Nandurkar, HH; Robson, SC; Selan, C | 1 |
| Laubach, VE | 1 |
| Däubener, W; Fischer, E; Heseler, K; Offers, M; Sattler, C; Schierl, R; Seissler, J; Steinsdoerfer, M | 1 |
| Di Virgilio, F; Donvito, G; Falzoni, S; Lemaire, I; Pellegatti, P | 1 |
| Belderbos, ME; Bont, L; Gallington, LC; Levy, O; Power Coombs, MR | 1 |
| Enk, AH; Mahnke, K; Ring, S | 1 |
| Eltzschig, HK; Robson, SC | 1 |
| Araujo, AG; Covas, DT; Ferreira, FI; Palma, PV; Panepucci, RA; Queiroz, RH; Saldanha-Araujo, F; Zago, MA | 1 |
| Chandran, PA; Dietl, J; Engel, JB; Fischer, B; Häusler, SF; Heuer, S; Hönig, A; Horn, E; Junker, M; Kloor, D; Klotz, KN; Kneitz, H; Krockenberger, M; Montalbán del Barrio, I; Ossadnik, M; Seida, AA; Strohschein, J; Wischhusen, J | 1 |
| Al-Taei, S; Clayton, A; Mason, MD; Tabi, Z; Webber, J | 1 |
| Bensussan, A; Carriere, M; Delaneau, O; Herbeck, JT; Huë, S; Hulin, A; Jenabian, MA; Kök, A; Lelievre, JD; Lévy, Y; Limou, S; Muhtarova, M; Mullins, JI; Nikolova, M; Schuitemaker, H; Seddiki, N; Younas, M; Zagury, JF | 1 |
| Anderson, AS; Khan, IU; Loza, MJ; O'Rourke, KS; Wood, J | 1 |
| Agorogiannis, EI; Cobbold, SP; Greaves, DR; Howie, D; Nolan, KF; Regateiro, FS; Waldmann, H | 1 |
| Burns, N; Gerasimovskaya, EV; Helenius, M; Jalkanen, S; Kaczmarek, E; Stenmark, K; Yegutkin, GG | 1 |
| Brusa, D; Coscia, M; D'Arena, G; Deaglio, S; Gaidano, G; Horenstein, AL; Inghirami, G; Laurenti, L; Malavasi, F; Robson, SC; Rossi, D; Serra, S; Tripodo, C; Vaisitti, T | 1 |
| Biragyn, A; Ferrucci, L; Goetzl, EJ; Hesdorffer, CS; Kennedy, RT; Longo, DL; Mabrouk, OS; Madara, K; Malchinkhuu, E; Schwartz, JB; Taub, DD | 1 |
| Dranoff, JA; Fausther, M; Kauffenstein, G; Lecka, J; Pelletier, J; Sévigny, J; Sheung, N; Soliman, E | 1 |
| Aiuti, A; Brigida, I; Carlucci, F; Carriglio, N; Clavenna, D; Gagliani, N; Hernandez, RJ; Poliani, PL; Roncarolo, MG; Sanvito, F; Sauer, AV; Scaramuzza, S; Tabucchi, A; Traggiai, E; Villa, A | 1 |
| Bönner, F; Borg, N; Burghoff, S; Schrader, J | 1 |
| Aurand, WL; Cowan, PJ; d'Apice, AJ; Dwyer, KM; Gumina, RJ; Huttinger, ZM; Long, LC; Milks, MW; Nickoli, MS; Robson, SC; Wheeler, DG | 1 |
| Brüne, B; Hahn, C; Roberts, E; Sekar, D; Weigert, A | 1 |
| Epstein, DL; Gonzalez, P; Li, G; Luna, C; Spasojevic, I; Wu, J | 1 |
| Cherkas, PS; Chiang, CY; Coderre, TJ; Dostrovsky, JO; Kumar, N; Sessle, BJ | 1 |
| Chia, JS; Cowan, PJ; Dwyer, KM; McRae, JL | 1 |
| Cowan, PJ; Dwyer, KM; Lu, B; Rajakumar, S; Roberts, V | 1 |
| Cobbold, SP; Regateiro, FS; Waldmann, H | 1 |
| Bai, X; Chen, F; Cui, M; Dong, Q; Li, T; Liu, X; Zhao, Y | 1 |
| Grden, M; Maciejewska, I; Pawelczyk, T; Sakowicz-Burkiewicz, M; Szutowicz, A | 1 |
| Carriere, M; Ghadimi, E; Hulin, A; Jenabian, MA; Kök, A; Lelievre, JD; Levy, Y; Routy, JP; Seddiki, N; Sévigny, J; Tremblay, A; Yatim, A; Younas, M | 1 |
| Insel, PA; Lu, D | 1 |
| Cheng, D; Hong, CS; Jackson, EK; Saze, Z; Schuler, PJ; Whiteside, TL | 1 |
| Huang, B; Huang, QB; Li, XG; Qu, X; Shao, QQ; Sun, JT; Wang, DH; Wang, XY; Xie, Q; Xu, S; Yang, N | 1 |
| Ito, MA; Kimura, J; Matsuoka, I; Murakawa, M; Takahashi-Sato, K | 1 |
| Buchanan, WG; Hilldorfer, BB; Jackson, EK; Macatangay, BJ; Mellors, JW; Riddler, SA; Rinaldo, CR; Saze, Z; Schuler, PJ; Whiteside, TL | 1 |
| Jeong, HJ; Kim, MK; Kim, SU; Lee, JJ; Lee, WW; Sung, C; Wee, WR; Yang, YH | 1 |
| Chan, ESL; Chiriboga, L; Cronstein, BN; Fernández, P; Franks, A; Perez-Aso, M; Robson, SC; Smith, G; Trzaska, S; Wilder, T | 1 |
| Araujo, AG; Covas, DT; Dias-Carlos, C; Elion, J; Ferreira, FI; Palma, PV; Panepucci, RA; Queiroz, RH; Saldanha-Araujo, F; Silva-Pinto, AC; Zago, MA | 1 |
| Aliagas, E; Condom, E; Martín-Satué, M; Ponce, J; Texidó, L; Vidal, A | 1 |
| Cheng, D; Gillespie, DG; Harasymczuk, M; Hong, CS; Jackson, EK; Lang, S; Mandapathil, M; Muller, L; Saze, Z; Schuler, PJ; Whiteside, TL | 1 |
| Ellies, LG; Gao, X; Jiang, JX; Riquelme, MA; Sun, LZ; Zhou, JZ | 1 |
| Cerrito, MG; Cinti, A; De Giorgi, M; Giovannoni, R; Lavitrano, M; Pelikant-Malecka, I; Sielicka, A; Slominska, EM; Smolenski, RT | 1 |
| Mittal, D; Smyth, MJ; Stagg, J; Young, A | 1 |
| Alexander, SI; Cowan, PJ; Dwyer, KM; Roberts, VS; Robson, SC | 1 |
| Acolty, V; Delrée, P; Francois, V; Moser, M; Oldenhove, G; Preyat, N; Shehade, H | 1 |
| Al-Abed, Y; Cheng, KF; Kaku, H; Rothstein, TL | 1 |
| Alberici, G; Bastid, J; Bec, N; Bensussan, A; Bonnefoy, N; Cochaud, S; Déjou, C; Eliaou, JF; Funck-Brentano, E; Giustiniani, J; Gros, L; Hemon, P; Laheurte, C; Laprevotte, E; Larroque, C; Regairaz, A | 1 |
| Chen, F; Cui, M; Ding, H; Dong, Q; Yang, Q; Zhao, Y | 1 |
| Marcillac, F; Raddatz, E; Robin, E | 1 |
| Almeida, SL; Alves-Filho, JC; Carregaro, V; Costa, DL; Cunha, FQ; Cunha, TM; Demarque, DP; Donate, PB; Ferreira, FI; Ferreira, SH; Figueiredo, F; França, RF; Gouvea, DR; Liew, FY; Lopes, NP; Louzada-Junior, P; Oliveira, RD; Peres, RS; Pinto, LG; Queiroz, RH; Silva, JS; Talbot, J | 1 |
| Cao, J; Chen, Y; Gao, Y; Li, P; Robson, SC; Wang, W; Wu, Y; Yang, J; Zhang, G | 1 |
| Cataño-Cañizalez, YG; Cortés-Garcia, JD; Cortez-Espinosa, N; Guzman-Flores, JM; Portales-Perez, DP; Rodríguez-Rivera, JG; Vargas-Morales, JM | 1 |
| Enk, AH; Jendrossek, V; Ledent, C; Mahnke, K; Probst, HC; Pushkarevskaya, A; Ring, S; Robson, SC; Schild, H; Wirsdörfer, F | 1 |
| Cristóvão, G; Cunha, RA; George, J; Gomes, CA; Gonçalves, FQ; Gonçalves, T; Meyer Fernandes, JR; Rodrigues, L | 1 |
| Alam, MS; Cavanaugh, C; Costales, MG; Williams, K | 1 |
| Fuentes, E; Palomo, I | 1 |
| Chiesa, S; Chillemi, A; Gattorno, M; Horenstein, AL; Imperatori, A; Malavasi, F; Morandi, F; Mortara, L; Pistoia, V; Quarona, V; Zanellato, S | 1 |
| Apetrei, C; Brocca-Cofano, E; Gillespie, DG; He, T; Jackson, EK; Ma, D; Macatangay, BJ; Pandrea, I; Policicchio, BB; Raehtz, KD; Rinaldo, CR; Stock, JL; Xu, C | 1 |
| Bono, MR; Fernández, D; Flores-Santibáñez, F; Rosemblatt, M; Sauma, D | 1 |
| Borel, N; Leonard, CA; Schoborg, RV | 1 |
| Cortés-Garcia, JD; Cortez-Espinosa, N; García-Hernández, MH; Guzmán-Flores, JM; Layseca-Espinosa, E; López-López, C; Portales-Cervantes, L; Portales-Pérez, DP | 1 |
| Alves-Filho, JC; Cunha, FQ; Cunha, TM; Louzada-Junior, P; Paschoal, JA; Peres, RS; Pinto, LG; Saraiva, AL; Veras, FP | 1 |
| Correia, J; Correia-de-Sá, P; Faria, M; Ferreirinha, F; Magalhães-Cardoso, MT; Silva, I; Silva-Ramos, M | 1 |
| Bai, A; Junger, WG; Moss, A; Robson, SC; Rothweiler, S; Serena Longhi, M; Wu, Y | 1 |
| Alfthan, K; Kerkelä, E; Laitinen, A; Laitinen, S; Lampinen, M; Larjo, A; Lehenkari, P; Räbinä, J; Siljander, P; Takatalo, M; Valkonen, S; Veijola, J | 1 |
| Ahlmanner, F; Bastid, J; Börjesson, L; Fredin, K; Gustavsson, B; Langenes, V; Ndah, TG; Quiding-Järbrink, M; Stenstad, H; Sundström, P; Theander, L | 1 |
| Gooding, WE; Mitsuhashi, M; Muller, L; Simms, P; Whiteside, TL | 1 |
| Eltzschig, HK; Ferrari, D; Gambari, R; Idzko, M; McNamee, EN | 1 |
| Amédée, T; Cunha, RA; George, J; Mulle, C | 1 |
| Anyanwu, AC; Burant, CF; Goonewardena, SN; Hyman, MC; Kanthi, Y; Petrovic-Djergovic, D; Pinsky, DJ; Rattan, R; Robichaud, P; Visovatti, SH; Wang, J | 1 |
| Quintana, FJ; Robson, S; Takenaka, MC | 1 |
| Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG | 1 |
| Bao, R; Deng, X; Hou, J; Li, J; Shui, X; Yang, T; Zhu, X | 1 |
| Dong, K; Gao, ZW; Zhang, HZ | 1 |
| Bhagwat, SP; Elliott, MR; Janssen, WJ; Munger, JC; Murphy, PS; Wang, J; Wright, TW | 1 |
| Adeola, O; Chen, R; Fay, WP; Jeong, SS; Ji, Y; Strawn, TL | 1 |
| de Vos, P; Faas, MM; Sáez, T | 1 |
| Bottari, NB; Da Silva, AS; de Sá, MF; do Carmo, GM; Doleski, PH; Grando, TH; Gressler, LT; Henker, LC; Leal, DB; Mendes, RE; Monteiro, SG | 1 |
| Felszeghy, S; Jákim, J; Joós, G; Kiss, B; Nagy, G; Papp, T; Sághy, T; Szamosi, R; Szondy, Z | 1 |
| Anvari, E; Ghalamfarsa, G; Hojjat-Farsangi, M; Jadidi-Niaragh, F; Kazemi, MH; Mohammadi, H; Raoofi Mohseni, S | 1 |
| Kettenmann, H; Matyash, M; Matyash, V; Wendt, S; Zabiegalov, O | 1 |
| Jiang, ZG; Longhi, MS; Moss, A; Robson, SC | 1 |
| Afshar-Kharghan, V; Cho, MS; Haemmerle, M; Hisamatsu, T; Hu, Q; Kunapuli, S; Li, D; Ma, Q; Mak, SLC; Mitamura, T; Noh, K; Park, H; Sood, AK | 1 |
| Benck, U; Breedijk, A; Heitzmann, M; Kälsch, AI; Kling, L; Krämer, BK; Leikeim, L; Porubsky, S; Yard, BA | 1 |
| Crespo, J; Kryczek, I; Liu, JR; Lyssiotis, C; Maj, T; Shao, I; Szeliga, W; Vatan, L; Wang, W; Wei, S; Zhang, H; Zhao, L; Zou, W | 1 |
| Lee, JS; Yilmaz, Ö | 1 |
| Dwyer, KM; Kishore, BK; Robson, SC | 2 |
| Abd El Samad, AA; El-Kharashi, OA; El-Waseef, DAA; Mohamed, DI; Nabih, ES | 1 |
| Horenstein, AL; Malavasi, F; Morandi, F; Rizzo, R | 1 |
| Davis, L; Jonker, SS; Louey, S; Musso, J; Nelson, JW; Soman, D | 1 |
| Allez, M; Bitoun, S; Dönnes, P; Florence, K; Gleizes, A; Hacein-Bey-Abina, S; Hincelin-Mery, A; Krzysiek, R; Le Grand, R; Ly, B; Mackay, F; Mariette, X; Nocturne, G; Pallardy, M; Paoletti, A; Pascaud, J; Pruvost, A; Roques, P | 1 |
| Aparicio, P; Baroja-Mazo, A; de Bejar, Á; El-Tayeb, A; Herrero, JI; Martínez-Alarcón, L; Müller, CE; Pelegrín, P; Pons, JA; Revilla-Nuin, B | 1 |
| Guan, W; Shi, L; Song, J; Wu, Z; Xu, W; Yang, L | 1 |
| Baldissera, MD; Baldisserotto, B; Da Silva, AS; Descovi, SN; Garzon, LR; Souza, CF; Stefani, LM; Zeppenfeld, CC | 1 |
| Chen, X; Gong, X; Jiang, R; Kuang, G; Li, K; Tie, H; Wan, J; Wang, B; Xie, T; Zhou, Q | 1 |
| Avan, A; Bahreyni, A; Ferns, GA; Fuiji, H; Hassanian, SM; Khazaei, M; Rezaei, M; Ryzhikov, M | 1 |
| Battaglin, F; Berger, MD; Cao, S; Cremolini, C; Falcone, A; Heinemann, V; Lenz, HJ; Lo, JH; Loupakis, F; Millstein, J; Naseem, M; Puccini, A; Soni, S; Stintzing, S; Tokunaga, R; Zhang, W | 1 |
| Harshe, RP; Longhi, MS; Robson, SC; Vuerich, M | 1 |
| Buchi, M; Festag, J; Hinterwimmer, L; Jaschinski, F; Kallert, SM; Kashyap, AS; Klar, R; Michel, S; Schell, M; Thelemann, T; Zippelius, A | 1 |
| Felici, C; Mannavola, F; Passarelli, A; Silvestris, F; Tucci, M | 1 |
| Colello, J; Dang, J; Fu, Q; Gu, J; Huang, F; Kandalam, U; Luo, Y; Wang, J; Wu, W; Xue, Y; Yuan, J; Zhang, X; Zheng, SG; Zheng, Y | 1 |
| Amigues, B; Augier, S; Bastid, J; Becquart, O; Bensussan, A; Bonnefoy, N; Chanteux, S; Courtois, R; Déjou, C; Docquier, A; Eliaou, JF; Gauthier, L; Giraudon-Paoli, M; Gourdin, N; Gros, L; Jecko, D; Michaud, HA; Morel, Y; Narni-Mancinelli, E; Paturel, C; Perrot, I; Rispaud-Blanc, H; Romagné, F; Rossi, B; Roussel, A; Vivier, E | 1 |
| Chen, H; Cheng, L; Cheng, Y; Ji, L; Ke, Y; Li, F; Liu, C; Lu, Y; Min, Z; Shao, X; Sun, L; Wu, B; Zhan, Y | 1 |
| Arbab, M; Aytan, D; Bezler, AK; Fakhari, M; Junger, WG; Kondo, Y; Ledderose, C; Slubowski, CJ; Sueyoshi, K; Sumi, Y | 1 |
| Lee, GR; Otterbein, LE; Shaefi, S | 1 |
| Burr, A; Parekkadan, B | 1 |
| Chen, X; Li, W; Li, Y; Li, Z; Liang, D; Olsen, N; Su, W; Yu, J; Zheng, SG; Zhu, W | 1 |
| Bernardes, VM; da Silva, JLG; Leal, DBR; Passos, DF | 1 |
| Adamiak, M; Brzezniakiewicz-Janus, K; Bujko, K; Kucia, M; Ratajczak, J; Ratajczak, MZ | 1 |
| Allard, B; Allard, D; Hammami, A; Stagg, J | 1 |
| Chia, C; Lim, JME; Ren, EC; Shen, M | 1 |
| Basu, M; Dutta, A; Gupta, P; Jana, K; Ukil, A | 1 |
| Chang, Y; Copeland, J; Shin, M; Venton, BJ; Wang, Y | 1 |
| Bastid, J; Bensussan, A; Bonnefoy, N; Eliaou, JF; Gros, L; Paturel, C; Perrot, I | 1 |
| Casey, M; Gandhi, MK; Nakamura, K; Oey, H; Smyth, MJ; Stagg, J; Vari, F | 1 |
| Borea, PA; Casetta, I; Gessi, S; Laudisi, M; Merighi, S; Pasquini, S; Varani, K; Vincenzi, F | 1 |
| Abdollahi, P; Borodovsky, A; Børset, M; Cooper, Z; Elsaadi, S; Hay, C; Kusnierczyk, A; Menu, E; Misund, K; Moen, SH; Rustad, E; Rø, TB; Schuller, AG; Slupphaug, G; Slørdahl, TS; Sponaas, AM; Standal, T; Sundan, A; Vandsemb, EN; Waage, A; Woessner, R; Yang, R | 1 |
| Battastini, AMO; Bertoni, APS; Braganhol, E; de Campos, RP; Stefani, GP; Tamajusuku, ASK; Wink, MR | 1 |
| Beckenkamp, LR; Bertoni, APS; da Fontoura, DMS; de Campos, RP; Iser, IC; Korb, VG; Lenz, G; Onzi, GR; Sévigny, J; Wink, MR | 1 |
| Gao, S; Luan, J; Lv, X; Qian, X; Wang, S; Zhou, D | 1 |
| Ghalamfarsa, G; Hajizadeh, F; Heydarzedeh Asl, S; Jadidi-Niaragh, F; Karoon Kiani, F; Masjedi, A; Peydaveisi, M; Sevbitov, A | 1 |
| Halpin-Veszeleiova, K; Hatfield, SM | 1 |
| Giatromanolaki, A; Hasan, F; Koukourakis, MI; Kouroupi, M; Mitrakas, A; Pappa, A; Pouliliou, S | 1 |
| Acosta Rodríguez, EV; Acosta, CDV; Amezcua Vesely, MC; Bossio, SN; Cadile, I; Ferrero, PV; Gruppi, A; Montes, CL; Mussano, E; Onetti, L; Ponce, NE; Zacca, ER | 1 |
| Ďurčo, F; Gille, C; Köstlin-Gille, N; Poets, CF | 1 |
| Churov, A; Zhulai, G | 1 |
| Allard, D; Bareche, Y; Buisseret, L; Carneiro, M; Chrobak, P; Communal, L; Cousineau, I; Lapointe, R; Mes-Masson, AM; Pommey, S; Provencher, D; Robson, SC; Stagg, J; Thebault, P | 1 |
| Cook, JL; Corcoran, DL; Degan, S; Erdmann, D; Havran, WL; Healy, E; Jiang, SW; Lai, C; Levinson, H; MacLeod, AS; Reid, C; Robson, SC; Rudolph, R; Spasojevic, I; Suwanpradid, J; Whitley, MJ; Zelac, DE; Zhang, JY | 1 |
| Eubler, K; Heikelä, H; Köhn, FM; Kunz, L; Mayerhofer, A; Missel, A; Mundt, N; Pickl, U; Popper, B; Poutanen, M; Spehr, M; Strauss, L; Trottmann, M; Walenta, L | 1 |
| Lv, XW; Shuai, C; Wang, S; Xia, GQ; Yuan, F | 1 |
| Alves-Filho, JC; Borges, MC; Caetité, D; Castro, ÍMS; Cunha, FQ; Cunha, TM; Damaceno, MA; Donate, PB; Ferreira, RG; Fonseca, DM; Kauffenstein, G; Linden, J; Melo, PH; Menezes-Silva, L; Nakaya, HI; Nascimento, DC; Oliveira, AER; Paschoal, JAR; Peres, RS; Piñeros, AR; Quesniaux, V; Ryffel, B; Toller-Kawahisa, JE; Veras, FP; Viacava, PR; Zamboni, DS; Zoppi, D | 1 |
| Chen, X; Ding, Z; Du, J; Gao, G; Gao, Y; He, C; Lyu, S; Zhao, Y | 1 |
| Chun, BJ; Kekenes-Huskey, PM; Pace, T; Rahmaninejad, H | 1 |
| Bagot, M; Bensussan, A; Bozonnat, A; de Masson, A; Dumont, M; Marie-Cardine, A; Ram-Wolff, C; Sonigo, G; Thonnart, N | 1 |
| Amaral, IPG; Araújo, JMG; de Sousa Dias, CN; de Sousa Palmeira, PH; Gois, BM; Guerra-Gomes, IC; Keesen, TSL; Peixoto, RF | 1 |
| Birnbaum, Y; Carlsson, L; Chen, H; Fjellström, O; Ryberg, E; Whatling, C; Ye, R; Ye, Y | 1 |
| Alix, E; Bertheau, C; Callet-Bauchu, E; Cros-Perrial, E; Devouassoux-Shisheboran, M; Dumontet, C; Harou, O; Jordheim, LP | 1 |
| Li, Y; Liang, XJ; Liu, L; Lyu, M; Ni, Q; Timashev, P; Wu, L; Xia, L; Xie, W; Yuan, Y; Zhang, Q; Zhang, Y | 1 |
| Dwyer, KM | 1 |
| Guo, S; Han, F; Zhu, W | 1 |
| Chen, L; Da, M; Enk, A; Mahnke, K; Ring, S | 1 |
| Duarte-Silva, E; Hartung, HP; Meuth, SG; Oliveira-Giacomelli, Á; Peixoto, CA; Ulrich, H | 1 |
| Al-Hroub, H; Idris, R; Lopez, V; Mirza, S; Müller, CE; Pelletier, J; Schäkel, L; Sévigny, J; Tolosa, E; Winzer, R | 1 |
| Bracci, C; Fia, M; Funaro, A; Marchisio, S; Ortolan, E; Quaglino, P; Ribero, S; Rumore, MR; Senetta, R; Tampieri, C; Yakymiv, Y | 1 |
| Cheng, XD; Li, YJ; Wang, JH; Wang, L; Yang, B; Yang, X; Yu, NW; Zhang, J; Zhang, Q; Zhang, X | 1 |
| Allard, B; Allard, D; Bareche, Y; Chrobak, P; Cousineau, I; Eeles, CB; Haibe-Kains, B; Jacoberger-Foissac, C; Koseoglu, S; Lake, AC; Masia, R; McNicoll, Y; Messaoudi, N; Pommey, S; Robson, SC; Rohatgi, N; Seo, H; Soucy, G; Stagg, J; Turcotte, S | 1 |
| Azambuja, JH; Begnini, K; Bertoni, APS; Braganhol, E; da Cruz, LLP; da Silveira, F; de Souza, PO; Gelsleichter, NE; Haas, CB; Hasko, G; Leite, RO; Mohr, KR; Prá, MD; Soares, MS; Spanevello, RM; Wink, MR | 1 |
Reviews
36 review(s) available for adenosine and apyrase
| Article | Year |
|---|---|
NTPDase and 5'-nucleotidase activities in physiological and disease conditions: new perspectives for human health.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Atherosclerosis; Blood Coagulation; Blood Platelets; Cell Communication; Demyelinating Diseases; Epilepsy; Humans; Metabolism, Inborn Errors; Myocardial Infarction; Neoplasms; Platelet Activation; Platelet Aggregation; Seizures; Signal Transduction; Tamoxifen; Thrombosis | 2007 |
The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Pancreas; Signal Transduction | 2012 |
The CD39-adenosinergic axis in the pathogenesis of renal ischemia-reperfusion injury.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Humans; Kidney; Kidney Transplantation; Reperfusion Injury; Signal Transduction | 2013 |
CD73 and adenosine generation in the creation of regulatory microenvironments.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cytokines; Humans; Inflammation Mediators; Mice; Signal Transduction; T-Lymphocytes, Regulatory; Transforming Growth Factor beta; Tumor Escape | 2013 |
Targeting cancer-derived adenosine: new therapeutic approaches.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; GPI-Linked Proteins; Humans; Immunosuppressive Agents; Mice; Molecular Targeted Therapy; Neoplasms; Purinergic P1 Receptor Antagonists | 2014 |
The role of adenosine receptors A2A and A2B signaling in renal fibrosis.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Autocrine Communication; Fibroblasts; Fibrosis; Humans; Kidney; Macrophages; Paracrine Communication; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Renal Insufficiency, Chronic; Signal Transduction | 2014 |
Extracellular adenosine generation in the regulation of pro-inflammatory responses and pathogen colonization.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Helicobacter Infections; Immunity, Innate; Inflammation; Mice; Salmonella Infections | 2015 |
Extracellular ATP metabolism on vascular endothelial cells: A pathway with pro-thrombotic and anti-thrombotic molecules.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Endothelial Cells; Endothelium, Vascular; Humans; Platelet Activation; Thrombosis | 2015 |
CD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppression.
Topics: 5'-Nucleotidase; Adenosine; Antigens, CD; Apyrase; Cell Differentiation; Humans; Immune Tolerance; T-Lymphocytes | 2015 |
Purinergic Signaling During Immune Cell Trafficking.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; Cell Communication; Cell Movement; Chemokines; Humans; Inflammation; Leukocytes; Lymphocyte Activation; Nucleotidases; Receptors, Purinergic; Signal Transduction | 2016 |
Regulation of the T Cell Response by CD39.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Antigens, CD; Apyrase; Autoimmune Diseases; Autoimmunity; Gene-Environment Interaction; Humans; Immune Tolerance; Infections; Inflammation; Lymphocyte Activation; Neoplasms; T-Lymphocytes | 2016 |
The role of adenosinergic pathway in human autoimmune diseases.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Antigens, CD; Apyrase; Autoimmune Diseases; Humans; Immune Tolerance; Immunologic Tests; Immunosuppression Therapy; Molecular Targeted Therapy; Receptors, Purinergic P1; Signal Transduction | 2016 |
Extracellular ATP and adenosine: The Yin and Yang in immune responses?
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Antigens, CD; Apyrase; Endothelial Cells; Humans; Immunity, Cellular; Inflammation; Receptors, Purinergic P1; Receptors, Purinergic P2X; Receptors, Purinergic P2Y | 2017 |
Adenosine and adenosine receptors in the immunopathogenesis and treatment of cancer.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; GPI-Linked Proteins; Humans; Mice; Neoplasms; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Adenosine A2; Signal Transduction; Tumor Escape | 2018 |
Purinergic signaling during intestinal inflammation.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Biomarkers; Dysbiosis; Exosomes; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammatory Bowel Diseases; Lymphocytes; Macrophages; Purines; Receptors, Aryl Hydrocarbon; Signal Transduction | 2017 |
Unfolding Role of a Danger Molecule Adenosine Signaling in Modulation of Microbial Infection and Host Cell Response.
Topics: 5'-Nucleotidase; Adenosine; Antigens, CD; Apyrase; Bacterial Infections; Epithelium; Humans; Receptors, Purinergic P1; Signal Transduction; T-Lymphocytes, Helper-Inducer | 2018 |
CD39-adenosinergic axis in renal pathophysiology and therapeutics.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; Humans; Kidney | 2018 |
The Role of Extracellular Adenosine Generation in the Development of Autoimmune Diseases.
Topics: 5'-Nucleotidase; Adenosine; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Apyrase; Autoimmune Diseases; Humans | 2018 |
Adenosine signaling: Next checkpoint for gastric cancer immunotherapy?
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Humans; Immunotherapy; Receptors, Purinergic P1; Signal Transduction; Stomach Neoplasms | 2018 |
The potential role of adenosine signaling in the pathogenesis of melanoma.
Topics: 5'-Nucleotidase; Adenosine; Apyrase; GPI-Linked Proteins; Humans; Melanoma; Signal Transduction | 2018 |
Dysregulation of Adenosinergic Signaling in Systemic and Organ-Specific Autoimmunity.
Topics: Adenosine; Antigens, Neoplasm; Apyrase; Autoimmune Diseases; Humans; Organ Specificity; Receptors, Purinergic P1; Signal Transduction; Tetraspanins | 2019 |
The metabolic milieu in melanoma: Role of immune suppression by CD73/adenosine.
Topics: 5'-Nucleotidase; Adenosine; Apyrase; Biomarkers, Tumor; GPI-Linked Proteins; Humans; Immune Tolerance; Immunosuppression Therapy; Immunotherapy; Melanoma; Receptors, Purinergic P1; Signal Transduction; Tumor Microenvironment | 2019 |
HO-1 and CD39: It Takes Two to Protect the Realm.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; Heme; Heme Oxygenase-1; Humans; Immunity, Innate | 2019 |
ATP and adenosine: Role in the immunopathogenesis of rheumatoid arthritis.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Apyrase; Arthritis, Rheumatoid; Biomarkers; GPI-Linked Proteins; Humans; Receptors, Purinergic P2X7; Signal Transduction | 2019 |
Targeting the adenosine pathway for cancer immunotherapy.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Humans; Immunotherapy; Neoplasms; Signal Transduction | 2019 |
Conversion of extracellular ATP into adenosine: a master switch in renal health and disease.
Topics: 5'-Nucleotidase; Acute Kidney Injury; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Carcinoma, Renal Cell; Diabetic Nephropathies; Graft Rejection; Humans; Immune Tolerance; Inflammation; Kidney Diseases; Kidney Neoplasms; Kidney Transplantation; Macrophages; Polycystic Kidney Diseases; Receptors, Purinergic P1; Receptors, Purinergic P2; Renal Insufficiency, Chronic; Reperfusion Injury; Signal Transduction; T-Lymphocytes, Regulatory | 2020 |
The role of the CD39-CD73-adenosine pathway in liver disease.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Humans; Liver Diseases; Signal Transduction | 2021 |
Adenosine and adenosine receptors in colorectal cancer.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Colorectal Neoplasms; Humans; Receptors, Purinergic P1 | 2020 |
Oxygenation and A2AR blockade to eliminate hypoxia/HIF-1α-adenosinergic immunosuppressive axis and improve cancer immunotherapy.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antigens, CD; Apyrase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immune Tolerance; Immunotherapy; Neoplasms; Oxygen; Receptor, Adenosine A2A; Tumor Hypoxia | 2020 |
Targeting adenosine and regulatory T cells in cancer immunotherapy.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Antineoplastic Agents; Apyrase; Forkhead Transcription Factors; Humans; Immunotherapy; Molecular Targeted Therapy; Neoplasms; T-Lymphocytes, Regulatory; Tumor Microenvironment | 2021 |
High-dimensional analysis of the adenosine pathway in high-grade serous ovarian cancer.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Antineoplastic Agents; Apyrase; Biomarkers, Tumor; Cell Line, Tumor; Databases, Genetic; Female; Gene Expression Profiling; GPI-Linked Proteins; Humans; Hydrolysis; Mice, Knockout; Middle Aged; Neoplasm Grading; Neoplasms, Cystic, Mucinous, and Serous; Ovarian Neoplasms; RNA-Seq; Signal Transduction; Single-Cell Analysis; Transcriptome; Xenograft Model Antitumor Assays | 2021 |
Burnstock oration - purinergic signalling in kidney transplantation.
Topics: Adenosine; Antigens, CD; Apyrase; Graft Survival; Humans; Kidney; Kidney Transplantation; Reperfusion Injury; Signal Transduction | 2022 |
CD39 - A bright target for cancer immunotherapy.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Apyrase; Humans; Immunotherapy; Neoplasms; Tumor Microenvironment | 2022 |
The Multifaceted Actions of CD73 During Development and Suppressive Actions of Regulatory T Cells.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; T-Lymphocytes, Regulatory | 2022 |
The adenosinergic signaling in the pathogenesis and treatment of multiple sclerosis.
Topics: Adenosine; Adenosine Deaminase; Apyrase; Humans; Multiple Sclerosis; Neurodegenerative Diseases; Receptors, Purinergic P1; Signal Transduction | 2022 |
Purinergic signaling: a potential therapeutic target for ischemic stroke.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Antigens, CD; Apyrase; Humans; Ischemic Stroke; Signal Transduction; Thrombosis | 2023 |
Trials
1 trial(s) available for adenosine and apyrase
| Article | Year |
|---|---|
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adolescent; Adult; Agammaglobulinemia; Animals; Antigens, CD; Apyrase; Autoantibodies; Child; Child, Preschool; Female; Forkhead Transcription Factors; Genetic Therapy; Hematopoietic Stem Cell Transplantation; Humans; Hypothyroidism; Immunohistochemistry; Infant; Male; Mice; Mice, Knockout; Polyethylene Glycols; Severe Combined Immunodeficiency; T-Lymphocytes, Regulatory | 2012 |
Other Studies
187 other study(ies) available for adenosine and apyrase
| Article | Year |
|---|---|
A membrane-bound enzyme in rabbit aorta capable of inhibiting adenosine-diphosphate-induced platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta; Apyrase; Cell Extracts; Cell Membrane; Phosphoric Monoester Hydrolases; Platelet Aggregation; Rabbits; Thrombosis | 1977 |
Platelet release and aggregation induced by antithymocyte globulin. In vitro effect of inhibitors.
Topics: Adenosine; Antilymphocyte Serum; Apyrase; Aspirin; Blood Platelets; Dipyridamole; Flurbiprofen; Humans; Phosphoric Monoester Hydrolases; Platelet Aggregation; Propionates; Prostaglandins E; Sulfinpyrazone; T-Lymphocytes | 1975 |
ADPase activity of isolated perfused rat lung.
Topics: Adenosine; Adenosine Monophosphate; Animals; Apyrase; Inosine; Lung; Phosphoric Monoester Hydrolases; Platelet Aggregation; Rabbits | 1978 |
Aggregation of gel-filtered guinea-pig platelets by lipoproteins.
Topics: Adenosine; Adenosine Diphosphate; Animals; Apyrase; Aspirin; Chromatography, Gel; Dipyridamole; Guinea Pigs; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Platelet Aggregation; Prostaglandins E | 1979 |
Collagen-induced platelet aggregation:--evidence against the essential role of platelet adenosine diphosphate.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Collagen; Humans; Platelet Aggregation; Serotonin; Sheep | 1979 |
Spontaneous platelet aggregation in arterial insufficiency: mechanisms and implications.
Topics: Adenosine; Adult; Aged; Angina Pectoris; Apyrase; Arterial Occlusive Diseases; Aspirin; Coronary Disease; Dipyridamole; Heparin; Hirudins; Humans; Ischemic Attack, Transient; Middle Aged; Myocardial Infarction; Platelet Aggregation; Prostaglandins E | 1976 |
Rat platelet aggregation by ATP. Aggregometrical and ultrastructural comparison with aggregations induced by ADP and collagen.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Aspirin; Blood Platelets; Collagen; Female; Humans; Male; Platelet Aggregation; Rats | 1976 |
Growth inhibition of transformed mouse fibroblasts by adenine nucleotides occurs via generation of extracellular adenosine.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Biological Transport; Blood; Cell Division; Cell Line, Transformed; Dipyridamole; Fibroblasts; Mice; Nucleotidases; Thioinosine; Uridine Triphosphate | 1988 |
Synergistic actions of paf-acether and sodium arachidonate in human platelet aggregation. 2. Unexpected results after aspirin intake.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine; Administration, Oral; Adult; Apyrase; Arachidonic Acids; Aspirin; Catechols; Drug Synergism; Epoprostenol; Humans; Indomethacin; Masoprocol; Platelet Activating Factor; Platelet Aggregation; Pyrazoles; Thromboxane B2; Time Factors; Umbelliferones | 1986 |
The anatomical distribution of ADPase activity in the rabbit aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta, Abdominal; Aorta, Thoracic; Apyrase; Inosine; Male; Phosphoric Monoester Hydrolases; Rabbits | 1982 |
Mechanism triggering platelet hemostatic plug formation in vivo.
Topics: Adenosine; Animals; Apyrase; Bleeding Time; Blood Platelets; Hemostasis; Rabbits | 1984 |
Synergistic responses and receptor occupancy in rabbit blood platelets.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Clomipramine; Drug Synergism; Epinephrine; Platelet Aggregation; Rabbits; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Yohimbine | 1982 |
Autoradiography-based cytochemical detection of ecto-ATPase, ecto-ADPase, 5'-nucleotidase, and extracellular adenosine production, employing 141Ce3+ as a capturing agent.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphatases; Animals; Apyrase; Autoradiography; Cell Line; Cerium Radioisotopes; Haplorhini; Histocytochemistry; Humans | 1995 |
Endogenous adenosine formation can regulate human neutrophil function.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Aorta; Apyrase; Endothelium, Vascular; Homeostasis; Humans; In Vitro Techniques; Interleukin-1; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purines; Stress, Physiological | 1994 |
Characterization of an ATP diphosphohydrolase activity (APYRASE, EC 3.6.1.5) in rat blood platelets.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Blood Platelets; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Rats; Rats, Wistar; Substrate Specificity | 1993 |
Coordinated inhibition of actin-induced platelet aggregation by plasma gelsolin and vitamin D-binding protein.
Topics: Actins; Adenosine; Adenosine Diphosphate; Animals; Apyrase; Aspirin; Dose-Response Relationship, Drug; Gelsolin; Humans; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Vitamin D-Binding Protein | 1993 |
Purification of pancreas type-I ATP diphosphohydrolase and identification by affinity labelling with the 5'-p-fluorosulphonylbenzoyladenosine ATP analogue.
Topics: Adenosine; Affinity Labels; Animals; Apyrase; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Intracellular Membranes; Isoenzymes; Kinetics; Molecular Weight; Octoxynol; Organelles; Pancreas; Solubility; Swine | 1995 |
Inhibition of ATP-diphosphohydrolase(apyrase) of Torpedo electric organ by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Apyrase; Binding Sites; Calcium; Cations, Divalent; Electric Organ; Hydrolysis; Kinetics; Magnesium; Nucleotides; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes; Torpedo | 1996 |
Kinetics of extracellular ATP hydrolysis by microvascular endothelial cells from rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cells, Cultured; Dipyridamole; Endothelium, Vascular; Enzyme Inhibitors; Female; Hydrolysis; Kinetics; Microcirculation; Nucleotidases; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1995 |
Purification of the blood vessel ATP diphosphohydrolase, identification and localisation by immunological techniques.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Animals; Aorta; Apyrase; Cattle; Glycoproteins; Immunoblotting; Immunohistochemistry; Molecular Sequence Data; Pancreas | 1997 |
ADP-mimicking platelet aggregation caused by rugosin E, an ellagitannin isolated from Rosa rugosa Thunb.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Apyrase; Blood Platelets; Calcium; Creatine Kinase; Humans; Hydrolyzable Tannins; Inositol Phosphates; Phosphocreatine; Plant Extracts; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Tannins; Thromboxane B2 | 1997 |
Purification and immunohistochemical localization of the ATP diphosphohydrolase in bovine lungs.
Topics: Adenosine; Affinity Labels; Animals; Apyrase; Cattle; Glycoproteins; Immunohistochemistry; Lung; Molecular Weight; Tissue Distribution | 1997 |
Hydrolysis of extracellular adenine nucleotides by equine epidydimal spermatozoa.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Epididymis; Horses; Hydrolysis; Kinetics; Male; Nucleotidases; Nucleotides; Spermatozoa; Time Factors | 1997 |
Divalent cation dependence and inhibition of Schistosoma mansoni ATP diphosphohydrolase by fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cations; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; Magnesium; Models, Molecular; Schistosoma mansoni | 1998 |
2-thioether 5'-O-(1-thiotriphosphate)adenosine derivatives as new insulin secretagogues acting through P2Y-Receptors.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; Enzyme Stability; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Nucleotides; Pancreas; Purinergic P2 Receptor Agonists; Sulfides; Swine; Thionucleotides | 1999 |
Osmotic cell swelling-induced ATP release mediates the activation of extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Apyrase; Cell Line; Cell Size; Chloride Channels; Cytochalasin B; Egtazic Acid; Enzyme Activation; Humans; Intestines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osmolar Concentration; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Suramin | 1999 |
The role of potassium in the regulation of adenosine production by ATP-diphosphohydrolase on the endothelial cell membrane.
Topics: Adenosine; Apyrase; Cations; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Ischemia; Membrane Proteins; Potassium; Umbilical Arteries | 2000 |
Identification and characterization of a novel hepatic canalicular ATP diphosphohydrolase.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Bile Canaliculi; Calcium; Chromatography, Agarose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kidney; Kinetics; Liver; Microsomes; Sodium Azide; Substrate Specificity; Swine; Time Factors; Tissue Distribution | 2000 |
A role for ectophosphatase in xenobiotic resistance.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Apyrase; Arabidopsis; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cycloheximide; Drug Resistance, Microbial; Drug Resistance, Multiple; Enzyme Induction; Genes, Fungal; Genes, Plant; Membrane Proteins; Models, Biological; Mutation; Nigericin; Phosphoric Monoester Hydrolases; Plant Leaves; Plant Proteins; Plants, Genetically Modified; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Xenobiotics | 2000 |
Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Apyrase; Cells, Cultured; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Kinetics; Luminescent Measurements; Membrane Proteins; Nucleoside-Diphosphate Kinase; Phosphates; Phosphorylation; Phosphotransferases (Phosphate Group Acceptor); Substrate Specificity | 2001 |
Phenylalanine and phenylpyruvate inhibit ATP diphosphohydrolase from rat brain cortex.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cerebral Cortex; Hydrolysis; Kinetics; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes | 2001 |
ATP potently modulates anion channel-mediated excitatory amino acid release from cultured astrocytes.
Topics: Adenosine; Adenosine Triphosphate; Amino Acids; Animals; Anions; Apyrase; Astrocytes; Cells, Cultured; Excitatory Amino Acids; Extracellular Space; Ion Channels; Osmolar Concentration; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley | 2002 |
ATPase and Adpase activities in synovial membrane of equine metacarpophalangeal joint.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphatases; Animals; Apyrase; Arthritis; Cytosol; Enzyme Inhibitors; Horses; In Vitro Techniques; Joints; Mitochondria; Subcellular Fractions; Synovial Membrane | 2002 |
5'-p-Fluorosulfonylbenzoyl adenosine inhibits progesterone synthesis in human placental mitochondria.
Topics: Adenosine; Apyrase; Binding Sites; Female; Humans; Kinetics; Mitochondria; Oxygen Consumption; Placenta; Pregnancy; Progesterone; Proteins | 2002 |
Secretion of IL-2 and IFN-gamma, but not IL-4, by antigen-specific T cells requires extracellular ATP.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Binding Sites; Calcium; CD4-Positive T-Lymphocytes; Cell Line; Cytokines; Epitopes, T-Lymphocyte; Extracellular Space; Female; Gene Expression Regulation; Hybridomas; Interferon-gamma; Interleukin-2; Interleukin-4; Interphase; Intracellular Fluid; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; T-Lymphocyte Subsets | 2003 |
Changes in nucleotide hydrolysis in rat blood serum induced by pentylenetetrazol-kindling.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Animals; Apyrase; Biomarkers; Brain; Convulsants; Disease Models, Animal; Epilepsy; Female; Hydrolysis; Kindling, Neurologic; Nucleotidases; Pentylenetetrazole; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission | 2003 |
Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphatases; Antigens, CD; Apyrase; Base Sequence; Cell Hypoxia; Cell Membrane Permeability; Cells, Cultured; DNA Primers; Endothelium, Vascular; Humans; Hydrolysis; Kinetics; Microcirculation; Neutrophil Activation; Neutrophils; Oxygen Consumption; Pyrophosphatases; Receptor, Adenosine A2B; Receptors, Purinergic P1; Signal Transduction; Up-Regulation | 2003 |
The mechanism of hydrolysis of adenosine di- and tri-phosphate catalysed by potato apyrase.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, CD; Apyrase; Catalysis; Humans; Hydrolysis; Nucleotides; Phosphates; Solanum tuberosum | 1957 |
Beneficial effects of CD39/ecto-nucleoside triphosphate diphosphohydrolase-1 in murine intestinal ischemia-reperfusion injury.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Capillaries; Cyclic AMP; Cytokines; Endothelium, Vascular; Gene Deletion; Intestine, Small; Ischemia; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; Oxidative Stress; Permeability; Peroxidase; Platelet Activation; Reperfusion Injury; Time Factors; Vascular Endothelial Growth Factor A | 2004 |
Triatoma infestans apyrases belong to the 5'-nucleotidase family.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Apyrase; Biological Evolution; Blood Platelets; Blotting, Southern; Blotting, Western; Cell Line; Chromatography; Chromatography, Gel; Cloning, Molecular; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Gene Library; Glycosylation; Humans; Insecta; Mass Spectrometry; Molecular Sequence Data; Peptides; Platelet Aggregation; Polymerase Chain Reaction; Recombinant Proteins; Saliva; Sequence Homology, Amino Acid; Triatoma; Trypanosoma cruzi | 2004 |
Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Blood Platelets; Bone Marrow Transplantation; Gene Expression; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Phenotype; Thrombosis; Transplantation Immunology | 2004 |
Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism.
Topics: Adenosine; Adenosine Triphosphatases; Antigens, CD; Apyrase; Base Sequence; Cell Adhesion; Cell Hypoxia; Cells, Cultured; DNA Primers; Endothelium, Vascular; Humans; Microcirculation; Neutrophils; Nucleotides | 2004 |
Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.
Topics: Adenosine; Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Biomarkers; Brain; Convulsants; Disease Models, Animal; Female; Guanosine; Guanosine Diphosphate; Hydrolysis; Inosine; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Pentylenetetrazole; Phosphopyruvate Hydratase; Purines; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Seizures; Time Factors; Up-Regulation | 2004 |
Comparative hydrolysis of extracellular adenine nucleotides and adenosine in synaptic membranes from porcine brain cortex, hippocampus, cerebellum and medulla oblongata.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Brain; Cerebellum; Cerebral Cortex; Extracellular Space; Hippocampus; Hydrolysis; Medulla Oblongata; Swine; Synaptic Membranes | 2004 |
Calcium increases in retinal glial cells evoked by light-induced neuronal activity.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Apyrase; Axons; Calcium; In Vitro Techniques; Light; Male; Neuroglia; Neurons; Purinergic Antagonists; Rats; Rats, Long-Evans; Retina; Retinal Ganglion Cells; Suramin; Tetrodotoxin | 2005 |
Lung epithelial cells release ATP during ozone exposure: signaling for cell survival.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Apyrase; Blotting, Western; Brefeldin A; Bronchi; Cell Line; Cell Line, Tumor; Cell Survival; Deoxyglucose; Egtazic Acid; Epithelial Cells; Exocytosis; Extracellular Signal-Regulated MAP Kinases; Glucose; Humans; Hydrolysis; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Ozone; Phosphorylation; Pyrophosphatases; Rats; Signal Transduction; Time Factors; Trachea | 2005 |
Ecto-hydrolysis of adenine nucleotides in rat blood platelets are altered by ovariectomy.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Cell Membrane; Enzyme Activation; Estrogen Replacement Therapy; Female; Hydrolysis; Ovariectomy; Rats; Rats, Wistar | 2005 |
A novel role of extracellular nucleotides in valve calcification: a potential target for atorvastatin.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Aged; Alkaline Phosphatase; Aortic Valve; Aortic Valve Stenosis; Apyrase; Atorvastatin; Biomarkers; Calcinosis; Cell Differentiation; Cells, Cultured; Drug Evaluation, Preclinical; Heptanoic Acids; Humans; Middle Aged; Osteoblasts; Pyrroles; Receptors, Purinergic P2; Second Messenger Systems | 2006 |
Effect of extracellular ATP on the human leukaemic cell line K562 and its multidrug counterpart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Apoptosis; Apyrase; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Membrane Permeability; Cell Survival; Drug Resistance, Multiple; Humans; K562 Cells; Kinetics; Phenotype; Protein Binding; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2X7; Thymidine; Tritium; Tumor Cells, Cultured; Uridine Triphosphate | 2006 |
Accumulation of extracellular ATP protects against acute reperfusion injury in rat heart endothelial cells.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; Cells, Cultured; Coronary Vessels; Endothelial Cells; Extracellular Fluid; Male; Myocardial Reperfusion Injury; Perfusion; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline | 2006 |
Fluorescent N2,N3-epsilon-adenine nucleoside and nucleotide probes: synthesis, spectroscopic properties, and biochemical evaluation.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Calcium; Cell Line; Cyclization; Enzyme Inhibitors; Fluorescent Dyes; Humans; Molecular Structure; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2Y1; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2006 |
Regulation of death and survival in astrocytes by ADP activating P2Y1 and P2Y12 receptors.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Apoptosis; Apyrase; Astrocytes; Cell Line, Tumor; Cell Survival; Humans; In Situ Nick-End Labeling; Protein Serine-Threonine Kinases; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thionucleosides; Tumor Necrosis Factor-alpha | 2006 |
ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Connexin 43; Endothelial Cells; Humans; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation | 2006 |
Cell biology. Purinergic chemotaxis.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Autocrine Communication; Blood Platelets; Cell Membrane; Chemotaxis, Leukocyte; Endothelial Cells; Mice; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptor, Adenosine A3; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Respiratory Burst; Signal Transduction | 2006 |
Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury.
Topics: Acute Kidney Injury; Adenosine; Animals; Antigens, CD; Apyrase; Female; Ischemic Preconditioning; Kidney; Kidney Function Tests; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Renal Artery; Renal Circulation; Reperfusion Injury | 2007 |
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Immunosuppression Therapy; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; T-Lymphocytes, Regulatory | 2007 |
Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Epithelium; Humans; Immunity, Innate; Lung; Mice; Mice, Mutant Strains; Permeability; Receptor, Adenosine A2A; Respiration, Artificial; Respiratory Distress Syndrome; Signal Transduction | 2007 |
CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury.
Topics: Adenosine; Adenosine Monophosphate; Animals; Antigens, CD; Apyrase; Disease Models, Animal; Enzyme Induction; Ischemic Preconditioning, Myocardial; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium | 2007 |
Fasciola gigantica: purification and characterization of adenosine deaminase.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apyrase; Chromatography; Electrophoresis, Polyacrylamide Gel; Fasciola; Hydrogen-Ion Concentration; Metals; Sheep; Substrate Specificity; Temperature | 2008 |
Purinergic receptor activation inhibits osmotic glial cell swelling in the diabetic rat retina.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Cell Size; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glucocorticoids; Male; Neuroglia; Osmosis; Oxidative Stress; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, Purinergic; Retina; Reverse Transcriptase Polymerase Chain Reaction; Triamcinolone | 2008 |
Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cell Differentiation; Cell Movement; Chemotaxis; HL-60 Cells; Humans; Hydrolysis; Mice; Mice, Knockout; Microscopy, Fluorescence; Neutrophils; RNA, Messenger | 2008 |
5'-p-Fluorosulfonyl benzoyl adenosine inhibits an ecto-ATP-diphosphohydrolase in the tegument surface of Taenia crassiceps cysticerci.
Topics: Adenosine; Affinity Labels; Animals; Antigens, CD; Apyrase; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Taenia | 2008 |
A cell wall-bound adenosine nucleosidase is involved in the salvage of extracellular ATP in Solanum tuberosum.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Triphosphate; Apyrase; Cell Wall; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; N-Glycosyl Hydrolases; Plant Tubers; Plants, Genetically Modified; Solanum tuberosum | 2008 |
Adenosine and inflammation: CD39 and CD73 are critical mediators in LPS-induced PMN trafficking into the lungs.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Cell Movement; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Lung Diseases; Male; Mice; Mice, Knockout; Neutrophils; Nucleotidases; Phosphorylation; Solubility; Transcription, Genetic | 2009 |
The impact of purinergic signaling on renal ischemia-reperfusion injury.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; In Situ Nick-End Labeling; Kidney; Mice; Mice, Knockout; Receptor, Adenosine A2A; Receptors, G-Protein-Coupled; Renal Circulation; Reperfusion Injury; Signal Transduction | 2008 |
CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Cell Proliferation; Cells, Cultured; Cytokines; Flow Cytometry; Gastric Mucosa; Gastritis; Helicobacter felis; Helicobacter Infections; Humans; Interferon-gamma; Mice; Mice, Inbred C57BL; Mucous Membrane; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 2009 |
CD4+CD25+ regulatory T cells suppress contact hypersensitivity reactions through a CD39, adenosine-dependent mechanism.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; CD4 Antigens; Cell Communication; Cell Proliferation; Dermatitis, Contact; E-Selectin; Endothelial Cells; Immune Tolerance; Interleukin-2 Receptor alpha Subunit; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; T-Lymphocytes, Regulatory | 2009 |
Vascular stasis, intestinal hemorrhage, and heightened vascular permeability complicate acute portal hypertension in cd39-null mice.
Topics: Acute Disease; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Capillary Permeability; Constriction, Pathologic; Disease Models, Animal; Gastrointestinal Hemorrhage; Hypertension, Portal; Ligation; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Nitric Oxide; Portal Pressure; Portal Vein; Splanchnic Circulation; Time Factors | 2009 |
Time-course changes in ectonucleotidase activities during experimental autoimmune encephalomyelitis.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Cell Membrane; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Multiple Sclerosis; Rats; Rats, Inbred Strains; Spinal Cord; Time Factors | 2009 |
Extracorporeal photophoresis augments function of CD4+CD25+FoxP3+ regulatory T cells by triggering adenosine production.
Topics: Adenosine; Antigens, CD; Apyrase; Case-Control Studies; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Female; Forkhead Transcription Factors; Graft vs Host Disease; Humans; Immunophenotyping; Immunosuppression Therapy; Interleukin-2 Receptor alpha Subunit; Lipopolysaccharide Receptors; Lymphocyte Activation; Male; Photopheresis; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Time Factors | 2009 |
Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adult; Animals; Antigens, CD; Apyrase; CD4-Positive T-Lymphocytes; Dipeptidyl Peptidase 4; Female; Flow Cytometry; Forkhead Transcription Factors; GPI-Linked Proteins; Humans; Immunosuppressive Agents; Interleukin-2 Receptor alpha Subunit; Male; Middle Aged; Receptor, Adenosine A2A; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Young Adult | 2010 |
Regulation of adenosine system at the onset of peritonitis.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Animals; Antigens, CD; Apyrase; Disease Models, Animal; Escherichia coli; Injections, Intraperitoneal; Interleukin-6; Mice; Mice, Inbred Strains; Peritonitis; Receptors, Interleukin-6; Receptors, Purinergic P1; Tumor Necrosis Factor-alpha | 2010 |
Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness.
Topics: Adenosine; Adenosine Triphosphate; Antigens, CD; Apyrase; CD8-Positive T-Lymphocytes; Clonal Anergy; Humans; Interferon-gamma; Interleukin-2; Lymphocytes, Tumor-Infiltrating; Lymphoma, Follicular; Neuroprotective Agents; Pyrimidines; Receptors, Purinergic P1; T-Lymphocytes, Regulatory; Triazines; Triazoles | 2009 |
CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis.
Topics: Adenosine; Adult; Antigens, CD; Apyrase; Cell Communication; Female; Flow Cytometry; Forkhead Transcription Factors; Humans; Interleukin-17; Male; Multiple Sclerosis; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2009 |
Adenosine and prostaglandin E2 cooperate in the suppression of immune responses mediated by adaptive regulatory T cells.
Topics: 5'-Nucleotidase; Adaptive Immunity; Adenosine; Amino Acids, Cyclic; Antigens, CD; Apyrase; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Immune Tolerance; Intracellular Space; Signal Transduction; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2010 |
Biochemical characterization of an ecto-ATP diphosphohydrolase activity in Candida parapsilosis and its possible role in adenosine acquisition and pathogenesis.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Candida; Cell Adhesion; Coenzymes; Cricetinae; Cricetulus; Enzyme Inhibitors; Epithelial Cells; Humans; Kinetics; Magnesium Chloride; Substrate Specificity; Virulence; Virulence Factors | 2010 |
Transgenic overexpression of CD39 protects against renal ischemia-reperfusion and transplant vascular injury.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Cold Ischemia; Humans; Kidney Cortex Necrosis; Mice; Mice, Transgenic; Models, Animal; Reperfusion Injury | 2010 |
Therapeutic potential for CD39 in renal transplantation: there is hope.
Topics: Adenosine; Antigens, CD; Apyrase; Delayed Graft Function; Humans; Kidney Transplantation; Receptor, Adenosine A2A; Reperfusion Injury; Transplantation Immunology | 2010 |
Inhibition of T-cell proliferation by murine multipotent mesenchymal stromal cells is mediated by CD39 expression and adenosine generation.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Cell Proliferation; Hepatocyte Growth Factor; Humans; Immunosuppressive Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitogens; Multipotent Stem Cells; Phenotype; T-Lymphocytes; Transforming Growth Factor beta | 2011 |
P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration.
Topics: Adenosine; Adenosine Triphosphate; Apyrase; Cell Fusion; Giant Cells; Hexokinase; Humans; Osteoclasts; RANK Ligand; Receptor, Adenosine A2A; Receptors, Purinergic P2X7 | 2011 |
Adenosine modulates Toll-like receptor function: basic mechanisms and translational opportunities.
Topics: 5'-Nucleotidase; Adenosine; Antigens, CD; Apyrase; Cyclic AMP; Humans; Immunity, Innate; Infant, Newborn; Toll-Like Receptors | 2011 |
Regulatory T cells from IL-10-deficient mice fail to suppress contact hypersensitivity reactions due to lack of adenosine production.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Calcium; Dermatitis, Contact; Interleukin-10; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Receptors, Purinergic P2X7; T-Lymphocytes, Regulatory | 2011 |
NT5E mutations and arterial calcifications.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Antigens, CD; Apyrase; Atherosclerosis; Calcinosis; Fibroblasts; Gene Deletion; Humans; Hydrolysis; Mutation; Phosphoric Diester Hydrolases; Pyrophosphatases | 2011 |
Mesenchymal stromal cells up-regulate CD39 and increase adenosine production to suppress activated T-lymphocytes.
Topics: Adenosine; Adenosine Deaminase; Antigens, CD; Apyrase; Bone Marrow Cells; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Growth Processes; Humans; Lymphocyte Activation; Mesenchymal Stem Cells; Receptor, Adenosine A2A; Signal Transduction; Stromal Cells; T-Lymphocytes; T-Lymphocytes, Regulatory; Up-Regulation | 2011 |
Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity.
Topics: 5'-Nucleotidase; Adenosine; Antigens, CD; Apyrase; Cell Line, Tumor; Cell Separation; Cytotoxicity, Immunologic; Female; Flow Cytometry; GPI-Linked Proteins; Humans; Immunohistochemistry; Killer Cells, Natural; Ovarian Neoplasms; Receptor, Adenosine A2A; RNA Interference; T-Lymphocytes | 2011 |
Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Antigens, CD; Apyrase; Caco-2 Cells; Cell Line, Tumor; Down-Regulation; Exosomes; GPI-Linked Proteins; Humans; Hydrolysis; Jurkat Cells; Mesothelioma; Phosphorylation; Pleural Neoplasms; T-Lymphocytes, Regulatory | 2011 |
CD39/adenosine pathway is involved in AIDS progression.
Topics: Adenosine; Antigens, CD; Apyrase; Biomarkers; Bulgaria; Cell Proliferation; Cells, Cultured; Disease Progression; Down-Regulation; Forkhead Transcription Factors; France; Gene Expression; HIV Infections; Humans; Lymphocyte Activation; Polymorphism, Genetic; Receptor, Adenosine A2A; Survival Rate; T-Lymphocytes, Regulatory | 2011 |
T-cell specific defect in expression of the NTPDase CD39 as a biomarker for lupus.
Topics: Adenosine; Adult; Aged; Antigens, CD; Apyrase; Biomarkers; Cell Proliferation; Cells, Cultured; Flow Cytometry; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Middle Aged; T-Lymphocytes; T-Lymphocytes, Regulatory; Xanthines | 2011 |
Generation of anti-inflammatory adenosine by leukocytes is regulated by TGF-β.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Antigens, CD; Antigens, Surface; Apyrase; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cytokines; Dendritic Cells; Forkhead Transcription Factors; Inflammation Mediators; Leukocytes; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; T-Lymphocytes, Regulatory; Transforming Growth Factor beta | 2011 |
Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Antigens, CD; Apyrase; Blotting, Western; Capillary Permeability; Cattle; Cell Proliferation; Cyclic AMP; Dextrans; DNA Primers; Endothelial Cells; Fluorescein-5-isothiocyanate; Hypoxia; Neovascularization, Pathologic; Pulmonary Artery; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; Vasa Vasorum | 2011 |
CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Antigens, CD; Antineoplastic Agents, Phytogenic; Apyrase; Autocrine Communication; Cell Death; Cell Differentiation; Cell Movement; Cell Survival; Etoposide; Extracellular Space; GPI-Linked Proteins; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Paracrine Communication; Receptor, Adenosine A2A; Tumor Cells, Cultured | 2011 |
Distinctive immunoregulatory effects of adenosine on T cells of older humans.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Antigens, CD; Apyrase; CD28 Antigens; Cells, Cultured; Chemotaxis; Cytokines; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Male; Middle Aged; Phenethylamines; Pyrimidines; T-Lymphocytes; Triazoles; Young Adult | 2012 |
Coexpression of ecto-5'-nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Guinea Pigs; Liver; Liver Cirrhosis; Rabbits; Rats; Rats, Sprague-Dawley | 2012 |
Resident cardiac immune cells and expression of the ectonucleotidase enzymes CD39 and CD73 after ischemic injury.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; B-Lymphocytes; Cells, Cultured; Erythrocytes; Female; Flow Cytometry; Granulocytes; Leukocytes; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocytes, Cardiac; T-Lymphocytes | 2012 |
Ectonucleotide triphosphate diphosphohydrolase-1 (CD39) mediates resistance to occlusive arterial thrombus formation after vascular injury in mice.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Carotid Artery Thrombosis; Cells, Cultured; Chlorides; Ferric Compounds; Mice; Mice, Transgenic; Platelet Activation; Platelet Aggregation; Receptors, Purinergic P2; Signal Transduction | 2012 |
Apoptotic tumor cells induce IL-27 release from human DCs to activate Treg cells that express CD69 and attenuate cytotoxicity.
Topics: Adenosine; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Apoptosis; Apyrase; Cell Line, Tumor; Cytotoxicity, Immunologic; Dendritic Cells; Female; Forkhead Transcription Factors; Humans; Interleukins; Lectins, C-Type; Lymphocyte Activation; Neoplasms; Receptors, Lysosphingolipid; T-Lymphocytes, Regulatory | 2012 |
Endogenous production of extracellular adenosine by trabecular meshwork cells: potential role in outflow regulation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Aqueous Humor; Cells, Cultured; Cyclic AMP; Extracellular Space; Gene Expression Regulation, Enzymologic; Glaucoma; Intraocular Pressure; Membrane Microdomains; Mice; Mice, Inbred Strains; Stress, Mechanical; Swine; Trabecular Meshwork | 2012 |
Involvement of ATP in noxious stimulus-evoked release of glutamate in rat medullary dorsal horn: a microdialysis study.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; Central Nervous System Sensitization; Dental Pulp; Glutamic Acid; Irritants; Male; Microdialysis; Molar; Mustard Plant; Plant Oils; Posterior Horn Cells; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; Trigeminal Caudal Nucleus; Xanthines | 2012 |
Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Cerebrovascular Circulation; Equilibrative Nucleoside Transport Proteins; Extracellular Space; Hypoxia; Hypoxia-Inducible Factor 1; Ischemic Attack, Transient; Ischemic Preconditioning; Male; Mice; Neurons; Neuroprotective Agents; Receptor, Adenosine A1; Regional Blood Flow; Xanthines | 2013 |
High glucose impairs ATP formation on the surface of human peripheral blood B lymphocytes.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylate Kinase; Antigens, CD; Apyrase; B-Lymphocytes; Cell Survival; Cells, Cultured; Glucose; Humans; Phosphorylation; Purinergic P2X Receptor Antagonists | 2013 |
Regulatory T cells negatively affect IL-2 production of effector T cells through CD39/adenosine pathway in HIV infection.
Topics: 5'-Nucleotidase; Adenosine; Antibodies, Monoclonal; Antigens, CD; Apyrase; Cell Proliferation; Cyclic AMP; DNA Methylation; HIV Infections; HIV-1; Humans; Interleukin-2; Lymphocyte Activation; Promoter Regions, Genetic; Receptor, Adenosine A2A; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2013 |
Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Collagen; Fibroblasts; Fibrosis; Gene Knockdown Techniques; Homeostasis; Hydrolysis; Male; Myocardium; Phenotype; Phosphorylation; Protein Isoforms; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Adenosine production by human B cells and B cell-mediated suppression of activated T cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Antigens, CD; Apyrase; B-Lymphocytes; Cell Communication; Cells, Cultured; Coculture Techniques; Cytokines; Flow Cytometry; GPI-Linked Proteins; Humans; Immune Tolerance; Lymphocyte Activation; Receptors, Purinergic P1; RNA, Messenger; T-Lymphocytes | 2013 |
Synergy between the ectoenzymes CD39 and CD73 contributes to adenosinergic immunosuppression in human malignant gliomas.
Topics: 5'-Nucleotidase; Adenosine; Antigens, CD; Apyrase; Brain Neoplasms; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Glioma; Humans; Immune Tolerance; Lymphocytes, Tumor-Infiltrating | 2013 |
Loss of ectonucleotidases from the coronary vascular bed after ischemia-reperfusion in isolated rat heart.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Triphosphatases; Aging; Animals; Antigens, CD; Apyrase; Coronary Vessels; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; Nucleotidases; Phosphoric Diester Hydrolases; Pyrophosphatases; Rats, Wistar; Reperfusion Injury | 2013 |
CD4⁺CD73⁺ T cells are associated with lower T-cell activation and C reactive protein levels and are depleted in HIV-1 infection regardless of viral suppression.
Topics: 5'-Nucleotidase; Adenosine; Adult; Aged; Antigens, CD; Apyrase; Biological Assay; C-Reactive Protein; Case-Control Studies; CD4-Positive T-Lymphocytes; Flow Cytometry; HIV Infections; HIV-1; Humans; Lymphocyte Activation; Mass Spectrometry; Middle Aged | 2013 |
CD39-mediated effect of human bone marrow-derived mesenchymal stem cells on the human Th17 cell function.
Topics: 5'-Nucleotidase; Adenosine; Antigens, CD; Apyrase; Bone Marrow Cells; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; GPI-Linked Proteins; Humans; Immune Tolerance; Mesenchymal Stem Cells; Oligonucleotide Array Sequence Analysis; Signal Transduction; Th17 Cells | 2014 |
Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antibiotics, Antineoplastic; Antigens, CD; Apyrase; Bleomycin; Dermis; Fibrosis; Mice; Mice, Knockout; Scleroderma, Systemic; Transforming Growth Factor beta1 | 2013 |
Hydroxycarbamide modulates components involved in the regulation of adenosine levels in blood cells from sickle-cell anemia patients.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adolescent; Adult; Anemia, Sickle Cell; Antigens, CD; Antisickling Agents; Apyrase; Blood Cells; Case-Control Studies; Child; Dipeptidyl Peptidase 4; Gene Expression Regulation, Enzymologic; GPI-Linked Proteins; Humans; Hydroxyurea; Metabolic Networks and Pathways; Middle Aged; Young Adult | 2014 |
High expression of ecto-nucleotidases CD39 and CD73 in human endometrial tumors.
Topics: 5'-Nucleotidase; Adenocarcinoma; Adenosine; Aged; Aged, 80 and over; Antigens, CD; Apyrase; Endometrial Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Middle Aged | 2014 |
Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells.
Topics: 5'-Nucleotidase; Adenosine; Antigens, CD; Apyrase; Cell Line; Cell Membrane; Cells, Cultured; Exosomes; Gene Expression; Humans; Immunophenotyping; Leukocytes, Mononuclear; Lymphocyte Activation; Neoplasms; Phenotype; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2014 |
Differential impact of adenosine nucleotides released by osteocytes on breast cancer growth and bone metastasis.
Topics: Adenosine; Adenosine Triphosphate; Alendronate; Animals; Apyrase; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Osteocytes; Receptor, Adenosine A2A; Receptors, Purinergic P2X; RNA Interference; RNA, Small Interfering; Signal Transduction; Transplantation, Heterologous | 2015 |
Functional analysis of expression of human ecto-nucleoside triphosphate diphosphohydrolase-1 and/or ecto-5'-nucleotidase in pig endothelial cells.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Animals; Antigens, CD; Apyrase; Endothelial Cells; Enzyme Assays; Gene Expression; Humans; Swine; Transfection | 2014 |
Intestinal immunopathology is associated with decreased CD73-generated adenosine during lethal infection.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Disease Models, Animal; Gene Expression; Gene Expression Regulation; Intestinal Diseases; Mice; Mice, Knockout; Receptor, Adenosine A2A; Receptor, Adenosine A2B; T-Lymphocyte Subsets; Toxoplasma; Transforming Growth Factor beta; Tretinoin | 2015 |
A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; B-Lymphocyte Subsets; Colitis; Disease Models, Animal; Gene Expression; Immunomodulation; Immunophenotyping; Interleukin-10; Male; Mice; Mice, Knockout; Models, Biological; Peritoneal Cavity; Phenotype | 2014 |
Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, CD; Apyrase; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Humans; Immune Tolerance; Killer Cells, Natural; Receptors, Purinergic P1; T-Lymphocytes, Regulatory | 2015 |
Mdivi-1 Protects Against Ischemic Brain Injury via Elevating Extracellular Adenosine in a cAMP/CREB-CD39-Dependent Manner.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Astrocytes; Blood-Brain Barrier; Brain Ischemia; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dynamins; Extracellular Space; Hydrolysis; Male; Mice, Inbred C57BL; Neuroprotective Agents; Quinazolinones; Receptor, Adenosine A1; Recovery of Function; Signal Transduction; Up-Regulation | 2016 |
A hypoxic episode during cardiogenesis downregulates the adenosinergic system and alters the myocardial anoxic tolerance.
Topics: 5'-Nucleotidase; Adaptation, Physiological; Adenosine; Adenosine Kinase; Animals; Antigens, CD; Apyrase; Chick Embryo; Energy Metabolism; Equilibrative Nucleoside Transport Proteins; Gene Expression Regulation, Developmental; Glycogen; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart; Hypoxia; Membrane Transport Proteins; Myocardium; Organogenesis; Proto-Oncogene Proteins c-akt; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction; Time Factors | 2015 |
Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Arthritis, Experimental; Arthritis, Rheumatoid; Biomarkers; Drug Resistance; Humans; Lymphocyte Count; Methotrexate; Mice, Inbred C57BL; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells | 2015 |
CD39+ regulatory T cells attenuate allergic airway inflammation.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Immunophenotyping; Immunosuppressive Agents; Lung; Lymphocyte Count; Mice; Mice, Knockout; Respiratory Hypersensitivity; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2015 |
Expression of CD73 and A2A receptors in cells from subjects with obesity and type 2 diabetes mellitus.
Topics: 5'-Nucleotidase; Adenosine; Adult; Antigens, CD; Apoptosis; Apyrase; Body Mass Index; CD8-Positive T-Lymphocytes; Diabetes Mellitus, Type 2; Gene Expression Regulation; GPI-Linked Proteins; Humans; Inflammation; Lymphocyte Subsets; Lymphocytes; Obesity; Phenethylamines; Receptor, Adenosine A2A; Triazines; Triazoles | 2015 |
Regulatory T cell-derived adenosine induces dendritic cell migration through the Epac-Rap1 pathway.
Topics: Actin Cytoskeleton; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cell Communication; Cell Movement; Dendritic Cells; Guanine Nucleotide Exchange Factors; Mice; rap1 GTP-Binding Proteins; Receptors, Adenosine A2; Signal Transduction; T-Lymphocytes, Regulatory | 2015 |
Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Cell Line; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Lipopolysaccharides; Mice, Inbred C57BL; Microglia; Pyrimidines; Receptors, Adenosine A2; Triazoles | 2015 |
CD56brightCD16- NK Cells Produce Adenosine through a CD38-Mediated Pathway and Act as Regulatory Cells Inhibiting Autologous CD4+ T Cell Proliferation.
Topics: 5'-Nucleotidase; Adenosine; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Apyrase; Arthritis, Juvenile; CD4-Positive T-Lymphocytes; CD56 Antigen; CD57 Antigens; Cell Proliferation; GPI-Linked Proteins; Humans; Killer Cells, Natural; Lymphocyte Activation; Membrane Glycoproteins; Receptors, IgG; Synovial Fluid | 2015 |
Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Chlorocebus aethiops; Chronic Disease; Cytokines; Dipeptidyl Peptidase 4; Humans; Macaca nemestrina; Male; Receptors, Antigen, T-Cell; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; T-Lymphocytes | 2015 |
Damage/Danger Associated Molecular Patterns (DAMPs) Modulate Chlamydia pecorum and C. trachomatis Serovar E Inclusion Development In Vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine; Adenosine Triphosphate; Apyrase; Benzyl Compounds; Chlamydia; Chlamydia trachomatis; Cyclic AMP; HeLa Cells; Host-Pathogen Interactions; Humans | 2015 |
Evaluation of the expression and function of the P2X7 receptor and ART1 in human regulatory T-cell subsets.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Adolescent; ADP Ribose Transferases; Adult; Antigens, CD; Apyrase; Cell Death; Cell Proliferation; Female; Gene Expression Regulation; GPI-Linked Proteins; Humans; Immunophenotyping; L-Selectin; Male; NAD; Phenethylamines; Primary Cell Culture; Receptors, Adenosine A2; Receptors, Purinergic P2X7; Signal Transduction; T-Lymphocyte Subsets; Triazines; Triazoles | 2016 |
Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Anti-Inflammatory Agents; Antigens, CD; Apyrase; Arthritis, Experimental; Cytokines; Disease Models, Animal; Extracellular Space; Fructosediphosphates; Glycolysis; Male; Metabolic Networks and Pathways; Mice; Receptor, Adenosine A2A; Rheumatic Fever; Signal Transduction | 2015 |
Impairment of ATP hydrolysis decreases adenosine A1 receptor tonus favoring cholinergic nerve hyperactivity in the obstructed human urinary bladder.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Antigens, CD; Apyrase; Electromyography; Female; Humans; Hydrolysis; In Vitro Techniques; Middle Aged; Muscle Contraction; Parasympathetic Nervous System; Receptor, Adenosine A1; Urinary Bladder Neck Obstruction | 2015 |
NADH oxidase-dependent CD39 expression by CD8(+) T cells modulates interferon gamma responses via generation of adenosine.
Topics: Adenosine; Adult; Aged; Antigens, CD; Apyrase; Blotting, Western; CD28 Antigens; CD3 Complex; CD8-Positive T-Lymphocytes; Chromatin Immunoprecipitation; Colon; Crohn Disease; Female; Flow Cytometry; Humans; Immunosuppressive Agents; Interferon-gamma; Intestinal Mucosa; Leukocytes, Mononuclear; Male; MAP Kinase Signaling System; Middle Aged; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NADPH Oxidases; NF-kappa B; Reactive Oxygen Species; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes, Cytotoxic; Young Adult | 2015 |
Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells Requires Co-Operation with T cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Antigens, CD; Apyrase; CD4-Positive T-Lymphocytes; Cell Proliferation; Extracellular Vesicles; GPI-Linked Proteins; Humans; Immune Tolerance; Immunosuppression Therapy; Lymphocyte Activation; Mesenchymal Stem Cells | 2016 |
Regulatory T Cells from Colon Cancer Patients Inhibit Effector T-cell Migration through an Adenosine-Dependent Mechanism.
Topics: Adenocarcinoma; Adenosine; Antigens, CD; Apyrase; Cells, Cultured; Coculture Techniques; Colonic Neoplasms; Human Umbilical Vein Endothelial Cells; Humans; T-Lymphocytes, Regulatory; Transendothelial and Transepithelial Migration | 2016 |
Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets.
Topics: Adenosine; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Apyrase; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Culture Media, Conditioned; Down-Regulation; Exosomes; Humans; Lectins, C-Type; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Neoplasms; Real-Time Polymerase Chain Reaction; RNA, Messenger; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Up-Regulation | 2016 |
Microglia-derived purines modulate mossy fibre synaptic transmission and plasticity through P2X4 and A1 receptors.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; Cells, Cultured; Excitatory Postsynaptic Potentials; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Mossy Fibers, Hippocampal; Neuronal Plasticity; Purinergic P2X Receptor Agonists; Purines; Receptors, Purinergic P2X4; Synaptic Transmission | 2016 |
Purinergic dysregulation in pulmonary hypertension.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Antihypertensive Agents; Apyrase; Arterial Pressure; Disease Models, Animal; Genetic Predisposition to Disease; Humans; Hydrolysis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Pulmonary Artery; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X1; Severity of Illness Index; Signal Transduction; Suramin; Vascular Remodeling; Ventricular Remodeling | 2016 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arterial Occlusive Diseases; Blood Coagulation; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hydrolysis; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monocytes; Phenotype; Platelet Activation; Thrombosis; Time Factors; Transfection | 2016 |
Adenosine and the adenosine A2A receptor agonist, CGS21680, upregulate CD39 and CD73 expression through E2F-1 and CREB in regulatory T cells isolated from septic mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Agonists; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blotting, Western; Cells, Cultured; Culture Media, Conditioned; Cyclic AMP Response Element-Binding Protein; E2F1 Transcription Factor; Mice, Inbred BALB C; Phenethylamines; Receptor, Adenosine A2A; RNA Interference; Sepsis; T-Lymphocytes, Regulatory; Up-Regulation | 2016 |
CD73 regulates anti-inflammatory signaling between apoptotic cells and endotoxin-conditioned tissue macrophages.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apoptosis; Apyrase; Cells, Cultured; Chemokine CXCL10; Chemokine CXCL2; Coculture Techniques; Cytokines; Lipopolysaccharides; Lung; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; RAW 264.7 Cells; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Signal Transduction; Toll-Like Receptor 4 | 2017 |
Recombinant soluble apyrase APT102 inhibits thrombosis and intimal hyperplasia in vein grafts without adversely affecting hemostasis or re-endothelialization.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Apyrase; Blood Platelets; Blood Vessels; Carotid Arteries; Cell Movement; Cell Proliferation; Coronary Vessels; Endothelial Cells; Endothelium, Vascular; Hemostasis; Humans; Hyperplasia; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet Aggregation; Prothrombin Time; Recombinant Proteins; Solubility; Thrombosis; Tunica Intima | 2017 |
Purinergic enzymatic activities in lymphocytes and cardiomyocytes of mice acutely infected by Trypanosoma cruzi modulating the inflammatory responses.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Chagas Disease; Disease Models, Animal; Female; Heart; Hematologic Tests; Hydrolysis; Lymphocytes; Mice; Myocardium; Myocytes, Cardiac; Parasitemia; Purines; Trypanosoma cruzi | 2017 |
Involvement of adenosine A3 receptors in the chemotactic navigation of macrophages towards apoptotic cells.
Topics: Adenosine; Animals; Apoptosis; Apyrase; Autocrine Communication; Chemotaxis, Leukocyte; Dexamethasone; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Knockout; Phagocytosis; Receptor, Adenosine A2A; Receptor, Adenosine A3; Signal Transduction; Thymocytes; Thymus Gland | 2017 |
The adenosine generating enzymes CD39/CD73 control microglial processes ramification in the mouse brain.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Antigens, CD; Apyrase; Brain; Brain Injuries; Cell Count; Cells, Cultured; Chemotaxis; Dipyridamole; Disease Models, Animal; Equilibrative Nucleoside Transporter 1; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microglia; Phenotype; Receptors, Purinergic P2Y12 | 2017 |
Role of ADP receptors on platelets in the growth of ovarian cancer.
Topics: Adenosine; Adoptive Transfer; Animals; Antigens, CD; Apoptosis; Apyrase; Blood Platelets; Cell Proliferation; Female; Gene Knockdown Techniques; Hematopoiesis; Humans; Mice, Inbred C57BL; Ovarian Neoplasms; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Ticagrelor | 2017 |
Changes in CD73, CD39 and CD26 expression on T-lymphocytes of ANCA-associated vasculitis patients suggest impairment in adenosine generation and turn-over.
Topics: 5'-Nucleotidase; Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Apyrase; C-Reactive Protein; Dipeptidyl Peptidase 4; Female; Glomerular Filtration Rate; GPI-Linked Proteins; Humans; Male; Middle Aged; T-Lymphocytes; Young Adult | 2017 |
Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apoptosis; Apyrase; B7-H1 Antigen; CTLA-4 Antigen; Female; GPI-Linked Proteins; Humans; Immune Tolerance; Interleukin-10; Interleukins; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Ovarian Neoplasms; Oxidative Stress; Oxygen; Receptor, Adenosine A2A; T-Lymphocytes, Regulatory; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Microenvironment | 2017 |
The protective effect of pentoxifylline versus silymarin on the pancreas through increasing adenosine by CD39 in a rat model of liver cirrhosis: Pharmacological, biochemical and histological study.
Topics: Adenosine; Amylases; Animals; Antigens, CD; Apyrase; Disease Models, Animal; Insulin-Secreting Cells; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Pancreas; Pentoxifylline; Protective Agents; Rats; Rats, Wistar; Silymarin; Transforming Growth Factor beta1 | 2018 |
Role of adenosine signaling in coordinating cardiomyocyte function and coronary vascular growth in chronic fetal anemia.
Topics: 5'-Nucleotidase; Adenosine; Anemia; Animals; Antigens, CD; Apyrase; Calcium Signaling; Chronic Disease; Coronary Vessels; Disease Models, Animal; Equilibrative Nucleoside Transport Proteins; Female; Fetal Diseases; Gene Expression Regulation, Developmental; Myocytes, Cardiac; Neovascularization, Physiologic; Pregnancy; Receptors, Purinergic P1; Sheep, Domestic | 2018 |
Methotrexate and BAFF interaction prevents immunization against TNF inhibitors.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antibody Formation; Antigens, CD; Apyrase; Autoimmune Diseases; B-Cell Activating Factor; B-Lymphocytes; Disease Models, Animal; Drug Resistance; Humans; Immunization; Macaca; Methotrexate; Mice; Mice, Transgenic; Tumor Necrosis Factor-alpha | 2018 |
Extracellular adenosine reversibly inhibits the activation of human regulatory T cells and negatively influences the achievement of the operational tolerance in liver transplantation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Aged; Animals; Apyrase; Cell Proliferation; Female; GPI-Linked Proteins; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Liver Transplantation; Lymphocyte Activation; Male; Mice; Middle Aged; Phosphorylation; Receptors, Adenosine A2; T-Lymphocytes, Regulatory; Transplantation Tolerance | 2019 |
Purinergic signalling displays a pro-inflammatory profile in spleen and splenic lymphocytes of Rhamdia quelen fed with a diet contaminated by fungal mycotoxin: Involvement on disease pathogenesis.
Topics: Adenosine; Adenosine Triphosphate; Aflatoxin B1; Animal Feed; Animals; Antigens, CD; Apyrase; Catfishes; Diet; Disease Models, Animal; Fish Diseases; Food Contamination; Fungi; Immunotoxins; Lymphocytes; Nucleotidases; Spleen | 2018 |
Ferulic Acid Protected from Kidney Ischemia Reperfusion Injury in Mice: Possible Mechanism Through Increasing Adenosine Generation via HIF-1α.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apoptosis; Apyrase; Coumaric Acids; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Kidney; Mice; Protective Agents; Reperfusion Injury | 2018 |
Prognostic Effect of Adenosine-related Genetic Variants in Metastatic Colorectal Cancer Treated With Bevacizumab-based Chemotherapy.
Topics: 5'-Nucleotidase; Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apyrase; Bevacizumab; Biomarkers, Tumor; Camptothecin; Cetuximab; Cohort Studies; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; GPI-Linked Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Receptors, Purinergic P1; Survival Rate | 2019 |
Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antineoplastic Agents, Immunological; Apyrase; Biomarkers, Tumor; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Gene Silencing; Humans; Immunity; Lymphocyte Activation; Mice; Neoplasms; Oligonucleotides, Antisense; T-Lymphocyte Subsets; Xenograft Model Antitumor Assays | 2019 |
Human gingival tissue-derived MSC suppress osteoclastogenesis and bone erosion via CD39-adenosine signal pathway in autoimmune arthritis.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Arthritis, Experimental; Arthritis, Rheumatoid; Autoimmune Diseases; Biomarkers; Cell Line; Female; Fibroblasts; Gingiva; Humans; Mesenchymal Stem Cells; Mice; Osteoclasts; Osteogenesis; Signal Transduction; Tomography, X-Ray Computed | 2019 |
Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antibodies, Blocking; Antigens, CD; Antineoplastic Agents; Apyrase; Cell Line, Tumor; Disease Models, Animal; Gene Knock-In Techniques; Humans; Leukocytes, Mononuclear; Melanoma; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxaliplatin; Survival Rate; T-Lymphocytes; Tumor Microenvironment | 2019 |
The abnormal function of CD39
Topics: Adenosine; Adenosine Triphosphate; Adult; Aged; Apyrase; Case-Control Studies; Dexamethasone; Female; Gene Expression; Humans; Immunophenotyping; Immunosuppressive Agents; Lymphocyte Count; Male; Middle Aged; Purpura, Thrombocytopenic, Idiopathic; Receptor, Adenosine A2A; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory | 2019 |
Frontline Science: Escherichia coli use LPS as decoy to impair neutrophil chemotaxis and defeat antimicrobial host defense.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Biomarkers; Chemotaxis, Leukocyte; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Host-Pathogen Interactions; Humans; Intracellular Space; Lipopolysaccharides; Mice; Mitochondria; Neutrophil Activation; Neutrophils; Peritonitis | 2019 |
Kinetics of MSC-based enzyme therapy for immunoregulation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Antigens, CD; Apyrase; Cell Death; Cell Proliferation; Humans; Hydrolysis; Immunomodulation; Interleukin-1beta; Kinetics; Lymphocytes; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Substrate Specificity | 2019 |
The cAMP-Adenosine Feedback Loop Maintains the Suppressive Function of Regulatory T Cells.
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Autoimmune Diseases; Cyclic AMP; Female; Lymphocyte Activation; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory; Uveitis | 2019 |
The Inhibition of CD39 and CD73 Cell Surface Ectonucleotidases by Small Molecular Inhibitors Enhances the Mobilization of Bone Marrow Residing Stem Cells by Decreasing the Extracellular Level of Adenosine.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Bone Marrow; Cell Movement; Cells, Cultured; Embryonic Stem Cells; Endothelial Progenitor Cells; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Signal Transduction; Small Molecule Libraries; Vasodilator Agents | 2019 |
CD39
Topics: Adenosine; Allergens; Antigens, CD; Apyrase; Carbamazepine; Case-Control Studies; Cells, Cultured; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Enzyme-Linked Immunospot Assay; Forkhead Transcription Factors; Genetic Association Studies; Genetic Predisposition to Disease; HLA-B15 Antigen; Humans; Immune Tolerance; Immunity, Cellular; Signal Transduction; T-Lymphocytes, Regulatory | 2020 |
Increased host ATP efflux and its conversion to extracellular adenosine is crucial for establishing
Topics: Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Leishmaniasis; Mice; Mice, Inbred BALB C | 2020 |
CD73 or CD39 Deletion Reveals Different Mechanisms of Formation for Spontaneous and Mechanically Stimulated Adenosine and Sex Specific Compensations in ATP Degradation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout | 2020 |
[A new generation of immunotherapies targeting the CD39/CD73/adenosine pathway to promote the anti-tumor immune response].
Topics: 5'-Nucleotidase; Adaptive Immunity; Adenosine; Antigens, CD; Apyrase; Humans; Immunotherapy; Molecular Targeted Therapy; Neoplasms; Signal Transduction | 2020 |
Targeting an adenosine-mediated "don't eat me signal" augments anti-lymphoma immunity by anti-CD20 monoclonal antibody.
Topics: Adenosine; Animals; Antibody-Dependent Cell Cytotoxicity; Antigens, CD20; Antineoplastic Agents, Immunological; Apyrase; Biomarkers; Cell Line, Tumor; Disease Models, Animal; Immunomodulation; Immunophenotyping; Kaplan-Meier Estimate; Killer Cells, Natural; Lymphoma; Macrophages; Mice; Mice, Knockout; Phagocytosis; Prognosis; Rituximab; Signal Transduction | 2020 |
Adenosinergic System Involvement in Ischemic Stroke Patients' Lymphocytes.
Topics: 5'-Nucleotidase; Adenosine; Aged; Aged, 80 and over; Antigens, CD; Apyrase; Brain Ischemia; Female; GPI-Linked Proteins; Humans; Ischemic Stroke; Lymphocytes; Male; Membrane Proteins; Phosphoproteins; Receptors, Purinergic P1; Stroke | 2020 |
Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Female; Humans; Mice; Mice, Inbred C57BL; Multiple Myeloma; Prognosis; Receptor, Adenosine A2A; Survival Rate | 2020 |
Biochemical analysis of ectonucleotidases on primary rat vascular smooth muscle cells and in silico investigation of their role in vascular diseases.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Aorta; Apyrase; Computer Simulation; GPI-Linked Proteins; Mice; Muscle, Smooth, Vascular; Nucleotides; Rats; Rats, Wistar; Vascular Diseases | 2020 |
Immortalization of Mesenchymal Stromal Cells by TERT Affects Adenosine Metabolism and Impairs their Immunosuppressive Capacity.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cell Differentiation; Cell Line, Transformed; Extracellular Space; Gene Expression Regulation; Humans; Immunosuppression Therapy; Jurkat Cells; Mesenchymal Stem Cells; Rats, Wistar; Telomerase | 2020 |
Ectonucleotidase CD73 and CD39 expression in non-small cell lung cancer relates to hypoxia and immunosuppressive pathways.
Topics: 5'-Nucleotidase; Adenosine; Adult; Aged; Aged, 80 and over; Antigens, CD; Apyrase; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Immune Tolerance; Lung Neoplasms; Male; Middle Aged | 2020 |
B cells from Patients with Rheumatoid Arthritis Show Conserved CD39-Mediated Regulatory Function and increased CD39 Expression After Positive Response to Therapy.
Topics: Adenosine; Apyrase; Arthritis, Rheumatoid; B-Lymphocytes; B-Lymphocytes, Regulatory; Case-Control Studies; Cytokines; Disease Management; Disease Susceptibility; Gene Expression; Humans; Immunomodulation; Lymphocyte Activation; Lymphocyte Count; T-Lymphocytes; Treatment Outcome | 2021 |
Modulatory activity of adenosine on the immune response in cord and adult blood.
Topics: 5'-Nucleotidase; Adenosine; Apyrase; Cell Proliferation; Fetal Blood; Flow Cytometry; GPI-Linked Proteins; Humans; Monocytes; Myeloid-Derived Suppressor Cells; Receptors, Purinergic P1; T-Lymphocytes | 2021 |
ENTPD1 (CD39) Expression Inhibits UVR-Induced DNA Damage Repair through Purinergic Signaling and Is Associated with Metastasis in Human Cutaneous Squamous Cell Carcinoma.
Topics: Adenosine; Apyrase; Carcinoma, Squamous Cell; DNA Damage; DNA Repair; Forkhead Transcription Factors; Humans; Interleukin-27; Memory T Cells; Neoplasm Metastasis; Programmed Cell Death 1 Receptor; Skin Neoplasms; Ultraviolet Rays | 2021 |
Testicular adenosine acts as a pro-inflammatory molecule: role of testicular peritubular cells.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adult; Aminopyridines; Animals; Apyrase; Cells, Cultured; Cytokines; GPI-Linked Proteins; Humans; Infertility, Male; Inflammation; Male; Mice; Mice, Inbred C57BL; Middle Aged; Receptor, Adenosine A2B; Receptors, Purinergic P1; RNA Interference; RNA, Small Interfering; Testis | 2021 |
CD39-mediated ATP-adenosine signalling promotes hepatic stellate cell activation and alcoholic liver disease.
Topics: 5'-Nucleotidase; Acetaldehyde; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Carbon Tetrachloride; Colchicine; Cytokines; Disease Models, Animal; Ethanol; Gene Knockdown Techniques; Hepatic Stellate Cells; Humans; Liver Diseases, Alcoholic; Mice, Inbred C57BL; Primary Cell Culture; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Tungsten Compounds | 2021 |
Sepsis expands a CD39
Topics: Adenosine; Animals; Antigens, CD; Apyrase; Cellular Reprogramming; Immune Tolerance; Macrophages; Mice; Plasma Cells; Receptor, Adenosine A2A; Sepsis | 2021 |
Identification of Novel CD39 Inhibitors Based on Virtual Screening and Enzymatic Assays.
Topics: Adenosine; Antigens, CD; Apyrase; Enzyme Assays; Molecular Docking Simulation | 2022 |
Crowding within synaptic junctions influences the degradation of nucleotides by CD39 and CD73 ectonucleotidases.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Synapses | 2022 |
Involvement of the CD39/CD73/adenosine pathway in T-cell proliferation and NK cell-mediated antibody-dependent cell cytotoxicity in Sézary syndrome.
Topics: 5'-Nucleotidase; Adenosine; Antibody-Dependent Cell Cytotoxicity; Antigens, CD; Apyrase; Cell Proliferation; Humans; Killer Cells, Natural; Sezary Syndrome; Skin Neoplasms | 2022 |
Downregulation of CD73 on CD4+ T cells from patients with chronic Chikungunya infection.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; CD4-Positive T-Lymphocytes; Chikungunya Fever; Down-Regulation; Graft vs Host Disease; Humans | 2022 |
Recombinant Apyrase (AZD3366) Against Myocardial Reperfusion Injury.
Topics: Adenosine; Animals; Apyrase; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Ticagrelor | 2023 |
Variability in CD39 and CD73 protein levels in uveal melanoma patients.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Antigens, CD; Apyrase; Humans; Melanoma | 2022 |
Biomimetic Nanocarriers Guide Extracellular ATP Homeostasis to Remodel Energy Metabolism for Activating Innate and Adaptive Immunity System.
Topics: Adaptive Immunity; Adenosine; Adenosine Triphosphate; Apyrase; Biomimetics; Energy Metabolism; Homeostasis; Humans; Neoplasms; Tumor Microenvironment | 2022 |
Protein kinase inhibitor ceritinib blocks ectonucleotidase CD39 - a promising target for cancer immunotherapy.
Topics: Adenosine; Adenosine Triphosphate; Antigens, CD; Antineoplastic Agents; Apyrase; Carcinoma, Non-Small-Cell Lung; Humans; Immunotherapy; Leukocytes, Mononuclear; Lung Neoplasms; Protein Kinase Inhibitors; Pyrimidines; Receptor Protein-Tyrosine Kinases; Sulfones; Tumor Microenvironment | 2022 |
CD39/CD73 dysregulation and adenosine metabolism contribute to T-cell immunosuppression in patients with Sézary syndrome.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Apyrase; Humans; Immune Tolerance; Immunosuppression Therapy; Sezary Syndrome; Skin Neoplasms; T-Lymphocytes | 2023 |
CD73 Inhibits cGAS-STING and Cooperates with CD39 to Promote Pancreatic Cancer.
Topics: 5'-Nucleotidase; Adenosine; Animals; Apyrase; CD8-Positive T-Lymphocytes; Cell Line; Humans; Mice; Pancreatic Neoplasms | 2023 |
ATPergic signaling disruption in human sepsis as a potential source of biomarkers for clinical use.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Apyrase; Biomarkers; Humans; Sepsis; Shock, Septic | 2023 |