adenine and stavudine

adenine has been researched along with stavudine in 94 studies

Research

Studies (94)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (3.19)18.2507
2000's58 (61.70)29.6817
2010's33 (35.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R1
Allen, SJ; Chen, MS; Cherrington, JM; Fuller, MD; Kunder, SC; Lesnikowski, Z; Mulato, AS; Schinazi, RF; Sommadossi, JP; Ussery, MA1
Cheng, B1
Miller, MD; Naeger, LK1
Birkus, G; Cihlar, T; Greenwalt, DE; Hitchcock, MJ1
Margot, NA; Miller, MD; Naeger, LK1
Bendele, RA; Richardson, FC1
Callens, S; Colebunders, R; De Schacht, C; Huyst, V1
Chadapaud, S; Hittinger, G; Jolly, P; Lafeuillade, A; Lambry, V; Philip, G1
Derse, D; Hill, SA; Lloyd, PA; McDonald, S; Wykoff, J1
Bassetti, D; Bassetti, M; Ciravegna, BW; Di Biagio, A; Ferrazin, A; Rosso, R1
Chapman, T; McGavin, J; Noble, S1
Cunningham, CK; McKinney, RE1
Boyle, BA1
Dressier, RM; James, CW; Steinhaus, MC; Szabo, S1
Domingo, P; Elías, MJ; Guerro, MF; Labarga, P; Llibre, JM; Palacios, R; Ruiz, MI; Santos, J; Terrón, JA1
Cheng, AK; Coakley, DF; DeJesus, E; Gallant, JE; Lu, B; Miller, MD; Pozniak, AL; Staszewski, S; Suleiman, JM; Toole, JJ1
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M1
Auclair, M; Capeau, J; Caron, M; Kornprobst, M; Lagathu, C; Lombès, A; Walker, UA1
Havlir, DV; Ignacio, CC; Koelsch, KK; Lu, B; Margot, N; Miller, MD; Strain, MC; Wong, JK1
Amin, J; Carr, A; Cooper, DA; McAllister, J; Winston, A1
Giacomet, V; Martelli, L; Merlo, M; Mora, S; Sciannamblo, M; Viganò, A1
Adam, A; Maserati, R; Schewe, CK; Wassmer, G; Weitner, L1
Aldrovandi, GM; Beretta, S; Giacomet, V; Luraschi, P; Martelli, L; Merlo, M; Mora, S; Rombolà, G; Viganò, A1
Manfredi, R1
Andreoni, M; Antinori, A; Bini, T; Bonora, S; Carosi, G; Castagna, A; Di Perri, G; Landonio, S; Merli, S; Nasta, P; Perno, CF; Quirino, T; Tozzi, V; Trotta, MP; Zaccarelli, M1
Antela, A; Domingo, P; Llibre, JM; Miralles, C; Moreno, S; Palacios, R; Pérez-Elías, MJ; Sánchez-de la Rosa, R; Santos, J1
Cheng, A; Lu, B; Margot, NA; Miller, MD1
Cartledge, J; Churchill, D; Fakoya, A; Hay, P; Johnson, M; Leen, C; Moyle, GJ; Murphy, M; Reilly, G; Sabin, CA; Scullard, G; Wilkins, E1
Bogner, J; Claas, GJ; Goebel, FD; Jülg, B1
Anastos, K; Cohen, M; Cole, S; Hessol, NA; Justman, J; Kaplan, RC; Lu, D; Shi, Q; Tien, PC; Vigen, C; Young, M1
Baba, M; De Clercq, E; Shi, M; Takao, S; Wang, X1
Borgonovo, S; Brambilla, P; Cafarelli, L; Giacomet, V; Mora, S; Viganò, A; Zamproni, I; Zuccotti, G1
Arnaiz, JA; Blanco, JL; de Lazzari, E; Garrabou, G; Gatell, JM; Laguno, M; Larrousse, M; Leon, A; Lonca, M; López, S; Mallolas, J; Martinez, E; Milinkovic, A; Miró, O; Vidal, S1
Ainsworth, J; Booth, C; Bradshaw, D; Geretti, AM; Malik, S; Pattery, T; Van Houtte, M; Waters, A1
Chantratitra, W; Kiertiburanakul, S; Manosuthi, W; Sungkanuparph, S1
Haraguchi, K; Kubota, Y; Takeda, S; Tanaka, H1
Cossarizza, A; Dentone, C; Di Biagio, A; Esposito, R; Ferraresi, R; Mussini, C; Nasi, M; Nemes, E; Pinti, M; Repetto, E; Rosso, R; Viscoli, C1
Doerries, R; Drechsler, H; Gass, A; Hardmeier, M; Kuhle, J; Mehling, M; Ruegg, S1
Ananworanich, J; Côté, HC; Hill, A; Hirschel, B; Jupimai, T; Kerr, SJ; Laopraynak, N; Nuesch, R; Ruxrungtham, K; Saenawat, S1
Guedj, R1
Fox, M; Long, L; Rosen, S; Sanne, I1
Borroto-Esoda, K; Feng, JY; Goodman, D; Kutty, N; Ly, JK; Margot, NA; Miller, MD; Myrick, F; Svarovskaia, ES; Wang, R; White, KL1
Cotter, BR; Currier, JS; Dubé, MP; Fichtenbaum, CJ; Gerschenson, M; Komarow, L; Mitchell, CK; Murphy, RL; Parker, RA; Squires, K; Stein, JH; Torriani, FJ1
Chen, SS; Cheng, AK; DeJesus, E; Enejosa, JV; Gallant, JE; Pozniak, AL; Winston, JA1
Atté, EF; Rasschaert, F; Reid, T; van Griensven, J; Zachariah, R1
Portilla, J1
Moreno, V; Valencia, ME1
Belsey, E; Berzins, B; Chen, D; Choi, J; da Silva, B; Gerschenson, M; Kim, C; Libutti, DE; McComsey, GA; Murphy, RL; Shore, J; Taiwo, B; Weinstein, J1
Calmy, A; Ford, N; Mills, E1
Colebunders, R; Lynen, L; van Griensven, J1
Borroto-Esoda, K; Harris, J; Lansdon, EB; Miller, MD; O'Neal, W; Svarovskaia, ES; Wakeford, C; Waters, JM; White, KL1
Benn, P; Cartledge, J; Edwards, SG; Linney, A; Moyle, G; Reilly, G; Ruff, C; Sabin, CA; Sauret-Jackson, V1
Andrade, A; Eshleman, SH; Flanigan, T; Flexner, C; Gross, R; Hogg, E; Lalama, C; Mildvan, D; Reisler, R; Rosenkranz, S; Salomon, N; Santana, J; Tierney, C; Wiggins, I1
Roehr, B1
Bangsberg, DR1
Amuron, B; Birungi, J; Bunnell, R; Coutinho, A; Foster, S; Grosskurth, H; Jaffar, S; Kyomuhangi, R; Levin, J; Mermin, J; Nabiryo, C; Namara, G; Ndembi, N; Opio, A; Tappero, JW1
Bender, MA; Flanigan, T; Freedberg, KA; Kumarasamy, N; Lu, Z; Mayer, KH; Schackman, BR; Scott, CA; Walensky, RP; Wang, B1
Altice, FL; Springer, SA1
Asboe, D; Dunn, D; Fearnhill, E; Gazzard, B; Pillay, D; Pozniak, A; Price, H1
Freedberg, KA; Loubiere, S; Meiners, C; Sloan, C; Yazdanpanah, Y1
Bénet, T; Billioud, C; Boibieux, A; Brochier, C; Chevallier, M; Cotte, L; Ferry, T; Miailhes, P; Scoazec, JY; Vanhems, P; Zoulim, F1
Curran, A; Ribera, E1
Chimsuntorn, S; Lueangniyomkul, A; Mankatitham, W; Manosuthi, W; Nilkamhang, S; Sungkanuparph, S; Suntisuklappon, B; Tantanathip, P; Thongyen, S1
Bygrave, H; Cleary, S; Ford, N; Gadot, L; Goemaere, E; Hilderbrand, K; Jouquet, G; Kranzer, K; Lee, J; Makakole, L; Trivino, L; Vlahakis, N1
Agu, KA; Akpoigbe, KJ; Badru, T; Chabikuli, O; Eluwa, GI; Hamelmann, C1
Gordon, M; Hampton, J; Johnson, B; Kuritzkes, DR; Marconi, VC; Moosa, MY; Ordonez, C; Sunpath, H; Wu, B1
Carda-Broch, S; Casas-Breva, I; Esteve-Romero, J; Peris-Vicente, J; Rambla-Alegre, M1
Bonovas, S; Hatzakis, A; Nikolopoulos, G; Tsiodras, S1
Hansen, BE; Janssen, HL; Koëter, T; Komuta, M; Rossing, HH; Schouten, JN; Van der Ende, ME; van der Valk, M; Verheij, J1
Crowther, NJ; Dickens, C; Dix-Peek, T; Duarte, R; Fox, MP; Ive, P; John, MA; Macphail, P; Maskew, M; Menezes, CN; Raal, F; Sanne, I; Van Amsterdam, D1
Côté, HC; Hukezalie, KR; Thumati, NR; Wong, JM1
Ananworanich, J; Chomchey, N; Gerschenson, M; Hongchookiat, P; Jadwattanakul, T; Kerr, SJ; Kim, JH; Mathajittiphun, P; Phanuphak, N; Phanuphak, P; Pinyakorn, S; Praihirunyakit, P; Rungrojrat, P; Shikuma, C; Teeratakulpisarn, N; Valcour, V1
Arnett, DK; Bagchi, S; Chi, BH; Heimburger, DC; Kabagambe, EK; Kiage, JN; Koethe, JR; Nyirenda, CK; Wellons, MF1
Bedogni, G; Cococcioni, L; Fabiano, V; Giacomet, V; Mora, S; Stucchi, S; Viganò, A; Zuccotti, GV1
Aghokeng, A; Belec, L; Bertagnolio, S; Bunupuradah, T; Burda, S; Cane, P; Cappelli, G; Charpentier, C; Dagnra, AY; de Wit, TF; Deshpande, AK; El-Katib, Z; Eshleman, SH; Fleury, HJ; Fokam, J; Ford, N; Gody, JC; Hamers, RL; Hawkins, CA; Holmes, S; Hosseinipour, MC; Jordan, MR; Kanki, PJ; Katzenstein, D; Koyalta, DD; Kumwenda, JJ; Lallemant, M; Lynen, L; Manosuthi, W; Marconi, VC; Margot, NA; Moussa, S; Ndung'u, T; Ngo-Giang-Huong, N; Nyambi, PN; Orrell, C; Peeters, M; Rhee, SY; Ruxrungtham, K; Schapiro, JM; Schuurman, R; Shafer, RW; Sigaloff, KC; Sirivichayakul, S; Smith, D; Stevens, W; Tang, MW; van Zyl, GU; Wallis, CL; Zolfo, M1
Charalambous, S; Churchyard, GJ; Grant, AD; Hoffmann, CJ; Lewis, JJ; Velen, K1
Gulholm, T; Jamani, S; Poynten, IM; Templeton, DJ1
Crowther, NJ; Dickens, C; Dix-Peek, T; Duarte, R; Evans, D; Menezes, CN; Prinsloo, A; Raal, F; Rassool, M; Sanne, I; Van Amsterdam, D1
Flint, OP; Wang, F1
Boulle, A; Chi, BH; Chimbetete, C; Egger, M; Fox, MP; Gerber, F; Gsponer, T; Hoffmann, CJ; Orrell, C; Prozesky, H; Rohr, J; Wandeler, G; Zwahlen, M1
Brennan, AT; Fox, MP; Long, L; Maskew, M; Sanne, I; Shearer, K1
Moyo, C; Vinikoor, MJ1
Bloch, N; Huber, AD; Ji, J; Kirby, KA; Landau, NR; Leslie, MD; Lucas, AD; Michailidis, E; Ong, YT; Puray-Chavez, MN; Sarafianos, SG; Schultz, ML1
Greeff, OB; Hurrell, T; Khwitshana, AK1
Guo, F; Li, T; Lin, Q; Shao, H; Sun, P; Tian, J; Xu, Y; Yu, W; Zhou, X1
Havens, PL; Hazra, R1
McGuigan, C; Pertusati, F; Serpi, M1
Arterburn, S; Castaño, E; Cheng, AK; Chuck, SL; Church, J; Deville, J; Enejosa, JV; Estripeaut, D; Gaur, A; Rathore, M; Rhee, MS; Saez-Llorens, X; White, K1

Reviews

11 review(s) available for adenine and stavudine

ArticleYear
Targeted therapy of human immunodeficiency virus-related disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine

1991
Mechanisms of HIV-1 nucleoside reverse transcriptase inhibitor resistance: is it all figured out?
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:3

    Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Drug Resistance, Microbial; HIV-1; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Tenofovir; Zidovudine

2001
Tenofovir disoproxil fumarate.
    Drugs, 2003, Volume: 63, Issue:15

    Topics: Adenine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Treatment Outcome

2003
Newer treatments for HIV in children.
    Current opinion in pediatrics, 2004, Volume: 16, Issue:1

    Topics: Adenine; Anti-Bacterial Agents; Anti-HIV Agents; Child; Deoxycytidine; Didanosine; Drug Therapy, Combination; Emtricitabine; Enfuvirtide; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Peptide Fragments; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir

2004
The continuing evolution of HIV therapy.
    The AIDS reader, 2003, Volume: 13, Issue:12

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Delayed-Action Preparations; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Monitoring; Emtricitabine; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Randomized Controlled Trials as Topic; Stavudine; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2003
Tenofovir-related nephrotoxicity: case report and review of the literature.
    Pharmacotherapy, 2004, Volume: 24, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adenine; Anti-HIV Agents; Clinical Chemistry Tests; Fanconi Syndrome; Female; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Time Factors; Treatment Outcome

2004
[AIDS: ethics and scientific investigation on human beings].
    Bulletin de la Societe de pathologie exotique (1990), 2008, Volume: 101, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Anti-HIV Agents; Azathioprine; Clinical Trials as Topic; Congresses as Topic; Cyclosporine; Developing Countries; Ditiocarb; Double-Blind Method; Drug Evaluation, Preclinical; Drug Therapy, Combination; Ethics Committees, Research; Human Experimentation; Humans; Informed Consent; Mass Media; Oligodeoxyribonucleotides, Antisense; Organophosphonates; Practice Guidelines as Topic; Stavudine; Tenofovir; Thionucleotides

2008
[Tenofovir as a strategy to avoid or limit adverse effects].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8

    Topics: Adenine; Anemia; Anti-HIV Agents; Antimetabolites; Clinical Trials as Topic; DNA, Mitochondrial; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Glucose Metabolism Disorders; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Multicenter Studies as Topic; Organophosphonates; Prospective Studies; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zidovudine

2008
Economic evaluation of ART in resource-limited countries.
    Current opinion in HIV and AIDS, 2010, Volume: 5, Issue:3

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cost-Benefit Analysis; Developing Countries; Drug Monitoring; Health Care Costs; HIV Infections; Humans; Organophosphonates; RNA, Viral; Stavudine; Tenofovir; Viral Load

2010
From old to new nucleoside reverse transcriptase inhibitors: changes in body fat composition, metabolic parameters and mitochondrial toxicity after the switch from thymidine analogs to tenofovir or abacavir.
    Expert opinion on drug safety, 2011, Volume: 10, Issue:3

    Topics: Adenine; Adipose Tissue; Body Composition; Dideoxynucleosides; Drug Substitution; Humans; Metabolism; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zidovudine

2011
Antiretrovirals for HIV Exposure Prophylaxis.
    Current medicinal chemistry, 2012, Volume: 19, Issue:35

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2012

Trials

22 trial(s) available for adenine and stavudine

ArticleYear
Evolution of lipid abnormalities in patients switched from stavudine- to tenofovir-containing regimens.
    Journal of acquired immune deficiency syndromes (1999), 2003, Aug-01, Volume: 33, Issue:4

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Double-Blind Method; Female; HIV Infections; Humans; Lipids; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; RNA, Viral; Stavudine; Tenofovir

2003
Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial.
    JAMA, 2004, Jul-14, Volume: 292, Issue:2

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Double-Blind Method; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Oxazines; Prospective Studies; Stavudine; Tenofovir; Viral Load

2004
Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected children.
    Antiviral therapy, 2005, Volume: 10, Issue:8

    Topics: Adenine; Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Child; Cyclopropanes; Dyslipidemias; Female; HIV Infections; HIV-1; Humans; Lipids; Male; Organophosphonates; Oxazines; Protease Inhibitors; Stavudine; Tenofovir; Treatment Outcome; Viral Load

2005
Resistance development over 144 weeks in treatment-naive patients receiving tenofovir disoproxil fumarate or stavudine with lamivudine and efavirenz in Study 903.
    HIV medicine, 2006, Volume: 7, Issue:7

    Topics: Adenine; Alkynes; Benzoxazines; Cyclopropanes; Double-Blind Method; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Treatment Outcome

2006
A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy.
    AIDS (London, England), 2006, Oct-24, Volume: 20, Issue:16

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Biomarkers; Body Fat Distribution; Dideoxynucleosides; Female; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lipids; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2006
Metabolic and anthropometric changes one year after switching from didanosine/stavudine to tenofovir in HIV-infected patients.
    European journal of medical research, 2007, Feb-26, Volume: 12, Issue:2

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Body Weight; CD4 Lymphocyte Count; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Didanosine; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Hemoglobins; HIV Infections; Humans; Lactic Acid; Male; Middle Aged; Organophosphonates; Phosphates; Skinfold Thickness; Stavudine; Tenofovir; Treatment Outcome; Triglycerides; Uric Acid; Viral Load

2007
Normalization of fat accrual in lipoatrophic, HIV-infected children switched from stavudine to tenofovir and from protease inhibitor to efavirenz.
    Antiviral therapy, 2007, Volume: 12, Issue:3

    Topics: Absorptiometry, Photon; Adenine; Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atrophy; Benzoxazines; Body Composition; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Female; HIV Protease Inhibitors; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Italy; Male; Organophosphonates; Prospective Studies; Protease Inhibitors; Stavudine; Tenofovir; Time Factors; Treatment Outcome; Viral Load

2007
The impact of reducing stavudine dose versus switching to tenofovir on plasma lipids, body composition and mitochondrial function in HIV-infected patients.
    Antiviral therapy, 2007, Volume: 12, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Body Composition; Cholesterol; Drug Administration Schedule; Female; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Lipodystrophy; Male; Middle Aged; Mitochondria; Organophosphonates; Oxygen Consumption; Stavudine; Tenofovir; Treatment Outcome; Triglycerides

2007
Effects of the change from Stavudine to tenofovir in human immunodeficiency virus-infected children treated with highly active antiretroviral therapy: studies on mitochondrial toxicity and thymic function.
    The Pediatric infectious disease journal, 2008, Volume: 27, Issue:1

    Topics: Adenine; Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood Glucose; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Child; DNA, Mitochondrial; Female; HIV Infections; Humans; Lipids; Male; Mitochondria; Organophosphonates; Stavudine; Tenofovir; Thymus Gland; Viral Load

2008
Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:6

    Topics: Absorptiometry, Photon; Adenine; Adult; Anti-HIV Agents; Body Fat Distribution; Didanosine; DNA, Mitochondrial; HIV Infections; Humans; Lamivudine; Lipids; Liver Function Tests; Organophosphonates; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Tenofovir; Thailand

2008
Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s.
    Journal of the American College of Cardiology, 2008, Aug-12, Volume: 52, Issue:7

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Brachial Artery; CD4 Lymphocyte Count; Cyclopropanes; Endothelium, Vascular; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Organophosphonates; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir; Time Factors; Zidovudine

2008
The 3-year renal safety of a tenofovir disoproxil fumarate vs. a thymidine analogue-containing regimen in antiretroviral-naive patients.
    AIDS (London, England), 2008, Oct-18, Volume: 22, Issue:16

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Creatinine; Double-Blind Method; Female; Glomerular Filtration Rate; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Phosphorus; Proteinuria; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Young Adult; Zidovudine

2008
Improvements in cheek volume in lipoatrophic individuals switching away from thymidine nucleoside reverse transcriptase inhibitors.
    HIV medicine, 2009, Volume: 10, Issue:6

    Topics: Absorptiometry, Photon; Adenine; Adult; Aged; Body Composition; Cheek; Dideoxynucleosides; Female; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Middle Aged; Organophosphonates; Quality of Life; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2009
Modified directly observed antiretroviral therapy compared with self-administered therapy in treatment-naive HIV-1-infected patients: a randomized trial.
    Archives of internal medicine, 2009, Jul-13, Volume: 169, Issue:13

    Topics: Adenine; Administration, Oral; Adolescent; Adult; Aged; Anti-HIV Agents; Deoxycytidine; Dose-Response Relationship, Drug; Emtricitabine; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lopinavir; Male; Middle Aged; Organophosphonates; Pyrimidinones; Retrospective Studies; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Young Adult

2009
Modified directly observed therapy to improve HIV treatment outcomes: little impact with potent, once-daily therapy in unselected antiretroviral-naïve patients.
    Current HIV/AIDS reports, 2009, Volume: 6, Issue:4

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Directly Observed Therapy; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; HIV Infections; HIV-1; Humans; Lopinavir; Medication Adherence; Organophosphonates; Pyrimidinones; Ritonavir; Self Administration; Stavudine; Tenofovir; Treatment Outcome

2009
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.
    Lancet (London, England), 2009, Dec-19, Volume: 374, Issue:9707

    Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine

2009
Metabolic benefits of switching to tenofovir/lamivudine after long-term use of stavudine/lamivudine in NNRTI-based antiretroviral regimens: a prospective study.
    The Journal of infection, 2011, Volume: 62, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Female; HIV Infections; Humans; Lamivudine; Lipid Metabolism; Male; Middle Aged; Organophosphonates; Prospective Studies; Stavudine; Tenofovir; Treatment Outcome

2011
The early effects of stavudine compared with tenofovir on adipocyte gene expression, mitochondrial DNA copy number and metabolic parameters in South African HIV-infected patients: a randomized trial.
    HIV medicine, 2013, Volume: 14, Issue:4

    Topics: Adenine; Adipocytes; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biomarkers; DNA Copy Number Variations; DNA, Mitochondrial; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Glucose; HIV Infections; Humans; Inflammation; Lipid Metabolism; Male; Middle Aged; Organophosphonates; Prospective Studies; Reverse Transcriptase Inhibitors; South Africa; Stavudine; Tenofovir

2013
A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine.
    Antiviral therapy, 2012, Volume: 17, Issue:8

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Diet; Drug Administration Schedule; Drug Substitution; Female; Glomerular Filtration Rate; Hemoglobins; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Peripheral Nervous System Diseases; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2012
Long-term body composition and metabolic changes in HIV-infected children switched from stavudine to tenofovir and from protease inhibitors to efavirenz.
    European journal of pediatrics, 2013, Volume: 172, Issue:8

    Topics: Absorptiometry, Photon; Adenine; Adolescent; Alkynes; Anti-Retroviral Agents; Benzoxazines; Blood Glucose; Body Composition; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Female; HIV Infections; Humans; Lamivudine; Linear Models; Lipids; Longitudinal Studies; Male; Organophosphonates; Stavudine; Tenofovir

2013
A randomized clinical trial comparing metabolic parameters after 48 weeks of standard- and low-dose stavudine therapy and tenofovir disoproxil fumarate therapy in HIV-infected South African patients.
    HIV medicine, 2014, Volume: 15, Issue:1

    Topics: Adenine; Adult; Alkynes; Analysis of Variance; Anthropometry; Anti-HIV Agents; Benzoxazines; Biomarkers; Body Composition; Cyclopropanes; DNA, Mitochondrial; Dose-Response Relationship, Drug; Drug Substitution; Female; Glucose; HIV Infections; Humans; Inflammation; Lamivudine; Lipid Metabolism; Male; Middle Aged; Phosphorous Acids; South Africa; Stavudine

2014
A randomized, open-label study of the safety and efficacy of switching stavudine or zidovudine to tenofovir disoproxil fumarate in HIV-1-infected children with virologic suppression.
    The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4

    Topics: Adenine; Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2015

Other Studies

61 other study(ies) available for adenine and stavudine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Adenine; Antiviral Agents; HIV Reverse Transcriptase; HIV-1; Kinetics; Organophosphonates; Phosphates; Rauscher Virus; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine

1996
Update on other antivirals.
    PI perspective, 1996, Issue:no 18

    Topics: Adenine; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Stavudine; Zalcitabine; Zidovudine

1996
Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors.
    Antiviral research, 2002, Volume: 54, Issue:1

    Topics: Adenine; Anti-HIV Agents; Antigens, CD34; Cell Line; Didanosine; Dideoxynucleosides; Epithelial Cells; Hematopoietic Stem Cells; Humans; Kidney Tubules, Proximal; Liver; Muscle, Skeletal; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Tumor Cells, Cultured; Zalcitabine; Zidovudine

2002
ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:7

    Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Catalysis; Drug Resistance, Viral; HIV Reverse Transcriptase; Mutation; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zidovudine

2002
Adefovir nephrotoxicity and mitochondrial DNA depletion.
    Human pathology, 2002, Volume: 33, Issue:5

    Topics: Adenine; Antiviral Agents; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; DNA, Mitochondrial; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Kidney Tubules; Mitochondria; Organophosphonates; Renal Insufficiency; Stavudine

2002
[Tenofovir in Study 903. Also effective and tolerable in first-line therapy].
    MMW Fortschritte der Medizin, 2002, Aug-22, Volume: 144, Issue:33-34

    Topics: Adenine; Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Treatment Outcome; Viral Load

2002
New uses for tenofovir: more questions about d4T.
    Project Inform perspective, 2003, Issue:35

    Topics: Adenine; Drug Therapy, Combination; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir

2003
Pancreatitis in an HIV-infected person on a tenofovir, didanosine and stavudine containing highly active antiretroviral treatment.
    The Journal of infection, 2003, Volume: 47, Issue:2

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; Didanosine; Drug Interactions; Female; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Pancreatitis; Ritonavir; Stavudine; Tenofovir

2003
Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.
    The Journal of infectious diseases, 2003, Aug-01, Volume: 188, Issue:3

    Topics: Adenine; Cell Line; Dideoxynucleosides; Human T-lymphotropic virus 1; Humans; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zalcitabine; Zidovudine

2003
Fatal lactic acidosis and mimicking Guillain-Barré syndrome in an adolescent with human immunodeficiency virus infection.
    The Pediatric infectious disease journal, 2003, Volume: 22, Issue:7

    Topics: Acidosis, Lactic; Adenine; Adolescent; Antiretroviral Therapy, Highly Active; Carbamates; Diagnosis, Differential; Didanosine; Disease Progression; Drug Therapy, Combination; Fatal Outcome; Female; Furans; Guillain-Barre Syndrome; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Organophosphonates; Organophosphorus Compounds; Risk Assessment; Severity of Illness Index; Stavudine; Sulfonamides; Tenofovir

2003
[Lipid profile and body fat--significant "side effect" of antiretroviral therapy. Tenofovir: favorable profile of adverse effects].
    MMW Fortschritte der Medizin, 2003, Apr-28, Volume: 145 Spec No 1

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Body Composition; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Humans; Lamivudine; Lipids; Organophosphonates; Organophosphorus Compounds; Oxazines; Stavudine; Tenofovir

2003
Improvement of dyslipidemia in patients switching from stavudine to tenofovir: preliminary results.
    AIDS (London, England), 2004, Jul-02, Volume: 18, Issue:10

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Hyperlipidemias; Male; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir

2004
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.
    AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12

    Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine

2004
The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro.
    AIDS (London, England), 2004, Nov-05, Volume: 18, Issue:16

    Topics: 3T3-L1 Cells; Adenine; Adipocytes; Animals; Apoptosis; Cell Differentiation; Didanosine; Dideoxynucleosides; HIV-1; HIV-Associated Lipodystrophy Syndrome; Lamivudine; Lipid Metabolism; Mice; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2004
Predictors of residual viremia in HIV-infected patients successfully treated with efavirenz and lamivudine plus either tenofovir or stavudine.
    The Journal of infectious diseases, 2005, Apr-01, Volume: 191, Issue:7

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; DNA, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Oxazines; RNA, Viral; Stavudine; Tenofovir; Viremia

2005
The use of a triple nucleoside-nucleotide regimen for nonoccupational HIV post-exposure prophylaxis.
    HIV medicine, 2005, Volume: 6, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chi-Square Distribution; HIV Infections; Humans; Lamivudine; Male; Nelfinavir; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Assessment; Risk-Taking; Stavudine; Tenofovir; Zidovudine

2005
A 12-month treatment with tenofovir does not impair bone mineral accrual in HIV-infected children.
    Journal of acquired immune deficiency syndromes (1999), 2005, Dec-01, Volume: 40, Issue:4

    Topics: Absorptiometry, Photon; Adenine; Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Density; Child; HIV Infections; Humans; Organophosphonates; Stavudine; Tenofovir

2005
Improved lipid profiles and maintenance of virologic control in heavily pretreated HIV-infected patients who switched from stavudine to tenofovir treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Jan-01, Volume: 42, Issue:1

    Topics: Adenine; Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Lipid Metabolism; Male; Middle Aged; Organophosphonates; Retrospective Studies; Stavudine; Tenofovir

2006
Improvement of dyslipidemia during different HAART regimens: tenofovir- versus stavudine-containing antiretroviral combinations.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, May-01, Volume: 42, Issue:9

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dyslipidemias; HIV Infections; Humans; Organophosphonates; Stavudine; Tenofovir

2006
Antiviral efficacy and genotypic resistance patterns of combination therapy with stavudine/tenofovir in highly active antiretroviral therapy experienced patients.
    Antiviral therapy, 2006, Volume: 11, Issue:2

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biological Evolution; Drug Administration Schedule; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; RNA, Viral; Stavudine; Tenofovir; Treatment Failure; Viral Load

2006
Sustained improvement of dyslipidaemia in HAART-treated patients replacing stavudine with tenofovir.
    AIDS (London, England), 2006, Jun-26, Volume: 20, Issue:10

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Dyslipidemias; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Prospective Studies; Risk Factors; Stavudine; Tenofovir

2006
Five-year data out on Viread.
    AIDS patient care and STDs, 2006, Volume: 20, Issue:12

    Topics: Adenine; Anti-HIV Agents; Double-Blind Method; Drug Administration Schedule; HIV Infections; Humans; Organophosphonates; Randomized Controlled Trials as Topic; Stavudine; Tenofovir

2006
Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens.
    Journal of acquired immune deficiency syndromes (1999), 2007, May-01, Volume: 45, Issue:1

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black People; Cholesterol; Cross-Sectional Studies; Cyclopropanes; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Fasting; Female; Hispanic or Latino; HIV Infections; HIV Protease Inhibitors; HIV Seronegativity; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Multivariate Analysis; Nelfinavir; Nevirapine; Organophosphonates; Ritonavir; Stavudine; Tenofovir; Triglycerides; United States; White People

2007
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Catalysis; Cell Line; Dose-Response Relationship, Drug; Endogenous Retroviruses; HIV-1; Humans; Kidney; Molecular Sequence Data; Organophosphonates; Polymerase Chain Reaction; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Stavudine; Swine; Swine, Miniature; Tenofovir; Virus Replication; Zidovudine

2007
Novel drug resistance pattern associated with the mutations K70G and M184V in human immunodeficiency virus type 1 reverse transcriptase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Adenine; Amino Acid Substitution; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2007
Tenofovir resistance among HIV-infected patients failing a fixed-dose combination of stavudine, lamivudine, and nevirapine in a resource-limited setting.
    AIDS patient care and STDs, 2007, Volume: 21, Issue:10

    Topics: Adenine; Adult; Anti-HIV Agents; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Thailand; Treatment Outcome

2007
Synthetic use of epoxy-sugar nucleosides.
    Nucleosides, nucleotides & nucleic acids, 2007, Volume: 26, Issue:6-7

    Topics: Adenine; Aluminum Compounds; Anti-HIV Agents; Carbohydrates; Epoxy Compounds; Nucleosides; Stavudine; Stereoisomerism; Thymine

2007
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement.
    Journal of neurovirology, 2008, Volume: 14, Issue:1

    Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine

2008
Cost and cost-effectiveness of switching from stavudine to tenofovir in first-line antiretroviral regimens in South Africa.
    Journal of acquired immune deficiency syndromes (1999), 2008, Jul-01, Volume: 48, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Cost-Benefit Analysis; Humans; Models, Biological; Organophosphonates; Quality of Life; South Africa; Stavudine; Tenofovir

2008
The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation.
    Journal of acquired immune deficiency syndromes (1999), 2008, Aug-01, Volume: 48, Issue:4

    Topics: Adenine; Antiretroviral Therapy, Highly Active; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Organophosphonates; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication

2008
Weight evolution in HIV-1 infected women in Rwanda after stavudine substitution due to lipoatrophy: comparison of zidovudine with tenofovir/abacavir.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009, Volume: 103, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Body Weight; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Organophosphonates; Rwanda; Stavudine; Tenofovir; Treatment Outcome; Weight Loss; Zidovudine

2009
[Atazanavir-induced nephrolithiasis].
    Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:2

    Topics: Adenine; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatitis D, Chronic; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lopinavir; Male; Nephrolithiasis; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir

2009
Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen.
    The Journal of antimicrobial chemotherapy, 2009, Volume: 63, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Adipose Tissue; Adult; Anti-HIV Agents; Body Fat Distribution; CD4 Lymphocyte Count; Deoxyguanosine; F2-Isoprostanes; Glutathione; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lopinavir; Male; Mitochondria; Organophosphonates; Pyrimidinones; Ritonavir; Stavudine; Tenofovir; Treatment Outcome; Viral Load

2009
Rationing antiretroviral therapy in Africa--treating too few, too late.
    The New England journal of medicine, 2009, Apr-30, Volume: 360, Issue:18

    Topics: Adenine; Africa; Anti-Retroviral Agents; CD4 Lymphocyte Count; Developing Countries; Drug Administration Schedule; Health Care Rationing; HIV Infections; Humans; Organophosphonates; Stavudine; Tenofovir; Viral Load

2009
Substituting tenofovir for stavudine in resource-limited settings: there are challenges ahead.
    AIDS (London, England), 2009, May-15, Volume: 23, Issue:8

    Topics: Adenine; Anti-HIV Agents; Developing Countries; Drug Therapy, Combination; HIV Infections; Humans; Organophosphonates; Stavudine; Tenofovir; Treatment Failure

2009
Mutations in the thumb-connection and RNase H domain of HIV type-1 reverse transcriptase of antiretroviral treatment-experienced patients.
    Antiviral therapy, 2009, Volume: 14, Issue:2

    Topics: Adenine; Alkynes; Amino Acid Substitution; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Genetic Variation; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Ribonuclease H, Human Immunodeficiency Virus; Stavudine; Tenofovir

2009
HIV clinics are halting enrolment of new patients as funding stalls, MSF warns.
    BMJ (Clinical research ed.), 2009, Jul-20, Volume: 339

    Topics: Adenine; Anti-HIV Agents; Developing Countries; Drug Costs; HIV Infections; Hospitals, Special; Humans; Organophosphonates; Stavudine; Tenofovir

2009
Cost-effectiveness of tenofovir as first-line antiretroviral therapy in India.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Feb-01, Volume: 50, Issue:3

    Topics: Adenine; Adult; Antifungal Agents; Antiretroviral Therapy, Highly Active; Cost-Benefit Analysis; Female; HIV Infections; Humans; India; Male; Organophosphonates; Stavudine; Survival Analysis; Tenofovir; Treatment Outcome; Zidovudine

2010
DAART for human immunodeficiency virus-infected patients: Studying subjects not at risk for nonadherence and use of untested interventions.
    Archives of internal medicine, 2010, Jan-11, Volume: 170, Issue:1

    Topics: Adenine; Administration, Oral; Adolescent; Adult; Aged; Anti-HIV Agents; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Emtricitabine; Female; Genotype; HIV Infections; HIV-1; Humans; Lopinavir; Male; Middle Aged; Organophosphonates; Patient Compliance; Pyrimidinones; Randomized Controlled Trials as Topic; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Young Adult

2010
Positive and negative drug selection pressures on the N348I connection domain mutation: new insights from in vivo data.
    Antiviral therapy, 2010, Volume: 15, Issue:2

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Case-Control Studies; Cyclopropanes; Databases, Genetic; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV Reverse Transcriptase; HIV-1; Humans; Logistic Models; Mutation; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2010
The role of nucleoside and nucleotide analogues in nodular regenerative hyperplasia in HIV-infected patients: a case control study.
    Journal of hepatology, 2011, Volume: 54, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Didanosine; Female; HIV Infections; Humans; Hyperplasia; Hypertension, Portal; Liver; Liver Regeneration; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir

2011
Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho.
    Journal of acquired immune deficiency syndromes (1999), 2011, Nov-01, Volume: 58, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cost-Benefit Analysis; Developing Countries; Female; Health Care Costs; HIV Infections; Humans; Lesotho; Male; Middle Aged; Organophosphonates; Pregnancy; Rural Population; Stavudine; Tenofovir; Zidovudine

2011
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria.
    BMC clinical pharmacology, 2012, Feb-27, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine

2012
High rate of K65R for antiretroviral therapy-naive patients with subtype C HIV infection failing a tenofovir-containing first-line regimen.
    AIDS (London, England), 2012, Aug-24, Volume: 26, Issue:13

    Topics: Adenine; Adult; Arginine; CD4 Lymphocyte Count; Cohort Studies; Drug Resistance, Viral; Female; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Lysine; Male; Mutation; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; South Africa; Stavudine; Tenofovir; Treatment Failure; Viral Load

2012
Monitoring of HAART regime antiretrovirals in serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography.
    The Analyst, 2012, Sep-21, Volume: 137, Issue:18

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chromatography, Liquid; Cyclopropanes; Drug Monitoring; Humans; Lamivudine; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2012
Risk factors and outcome of HIV-associated idiopathic noncirrhotic portal hypertension.
    Alimentary pharmacology & therapeutics, 2012, Volume: 36, Issue:9

    Topics: Adenine; Adult; Anti-HIV Agents; Case-Control Studies; Chemical and Drug Induced Liver Injury; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Hypertension, Portal; Liver; Male; Middle Aged; Multivariate Analysis; Netherlands; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Young Adult

2012
In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Didanosine; Dideoxynucleosides; DNA Primers; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Telomerase; Tenofovir; Zidovudine

2012
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
    Lipids in health and disease, 2013, Apr-10, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine

2013
Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine.
    The Journal of infectious diseases, 2013, Jun-15, Volume: 207 Suppl 2

    Topics: Adenine; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cyclopropanes; Databases, Factual; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Mutation, Missense; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Tenofovir; Zidovudine

2013
Comparison of tenofovir, zidovudine, or stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Female; Health Resources; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Residence Characteristics; RNA, Viral; Stavudine; Tenofovir; Young Adult; Zidovudine

2013
Non-occupational HIV post-exposure prophylaxis at a Sydney metropolitan sexual health clinic.
    Sexual health, 2013, Volume: 10, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Australia; Deoxycytidine; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; HIV Infections; Homosexuality, Male; Humans; Male; Middle Aged; Organophosphonates; Post-Exposure Prophylaxis; Practice Guidelines as Topic; Practice Patterns, Physicians'; Risk-Taking; Stavudine; Tenofovir

2013
BMS-986001, an HIV nucleoside reverse transcriptase inhibitor, does not degrade mitochondrial DNA in long-term primary cultures of cells isolated from human kidney, muscle, and adipose tissue.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Adenine; Adipocytes; DNA Fragmentation; DNA, Mitochondrial; Epithelial Cells; Humans; Kidney Tubules, Proximal; Mitochondria; Muscle Fibers, Skeletal; Organophosphonates; Primary Cell Culture; Reverse Transcriptase Inhibitors; Stavudine; Structure-Activity Relationship; Tenofovir; Thymidine

2013
Tenofovir or zidovudine in second-line antiretroviral therapy after stavudine failure in southern Africa.
    Antiviral therapy, 2014, Volume: 19, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Retreatment; South Africa; Stavudine; Tenofovir; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine

2014
Impact of choice of NRTI in first-line antiretroviral therapy: a cohort analysis of stavudine vs. tenofovir.
    Tropical medicine & international health : TM & IH, 2014, Volume: 19, Issue:5

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Female; Follow-Up Studies; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Proportional Hazards Models; Prospective Studies; South Africa; Stavudine; Survival Analysis; Survival Rate; Tenofovir; Treatment Outcome; Viral Load; Young Adult

2014
Leveraging rapid implementation of an HIV treatment policy to reduce confounding in observational analysis of antiretroviral outcomes.
    Tropical medicine & international health : TM & IH, 2014, Volume: 19, Issue:5

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Male; Organophosphonates; Stavudine; Tenofovir

2014
SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Adenine; Cell Line; Dideoxynucleotides; Gene Expression; Genes, Reporter; HIV Reverse Transcriptase; HIV-1; Host-Pathogen Interactions; Humans; Lamivudine; Luciferases; Monocytes; Monomeric GTP-Binding Proteins; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Small Interfering; SAM Domain and HD Domain-Containing Protein 1; Stavudine; Tenofovir; Virus Replication; Zidovudine

2014
Assessing adherence to the 2010 antiretroviral guidelines at the antiretroviral rollout clinic in 1 military hospital, South Africa: a retrospective, cross sectional study.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2014, Jun-17, Volume: 104, Issue:7

    Topics: Adenine; Adult; Anti-Retroviral Agents; Cross-Sectional Studies; Drug Monitoring; Drug Substitution; Female; Guideline Adherence; HIV Infections; Hospitals, Military; Humans; Male; Organophosphonates; Outcome Assessment, Health Care; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; South Africa; Stavudine; Tenofovir

2014
[To evaluate the changes in body composition in male human immunodeficiency virus-related lipodystrophy after different treatment regimens by dual-energy X-ray absorptiometry].
    Zhonghua nei ke za zhi, 2014, Volume: 53, Issue:8

    Topics: Absorptiometry, Photon; Adenine; Anti-HIV Agents; Antiviral Agents; Body Composition; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2014
Commentary: The place of tenofovir disoproxil fumarate in pediatric antiretroviral therapy.
    The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Stavudine; Zidovudine

2015
Symmetrical diamidate prodrugs of nucleotide analogues for drug delivery.
    Current protocols in nucleic acid chemistry, 2015, Mar-09, Volume: 60

    Topics: Adenine; Antiviral Agents; Drug Delivery Systems; Humans; Nucleotides; Organophosphonates; Phosphorus Compounds; Prodrugs; Stavudine

2015
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