acronine and ellipticine

acronine has been researched along with ellipticine* in 2 studies

Reviews

1 review(s) available for acronine and ellipticine

Article	Year
Natural products as anticancer agents. Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1994, Volume: 42 Topics: Acronine; Animals; Antineoplastic Agents, Phytogenic; Ellipticines; Harringtonines; Humans; Maytansine; Paclitaxel; Panax; Plants, Medicinal; Podophyllin; Vinca Alkaloids	1994

Other Studies

1 other study(ies) available for acronine and ellipticine

Article	Year
Synthesis and cytotoxic activity of pyranocarbazole analogues of ellipticine and acronycine. Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:5 Various 2,2,5,11-tetramethyl- and 2,2,5,6,11-pentamethyl-2,6-dihydropyrano[3,2-b]carbazole derivatives were synthesized by condensation of 3-methylbut-2-enal or 3-chloro-3-methylbut-1-yne with an appropriate hydroxycarbazole. These compounds associate the tricyclic system responsible for the intercalating properties of ellipticine related drugs, with the dimethylpyran pharmacophore of acronycine derivatives. The study of the biological properties of the new pyrano[3,2-b]carbazole derivatives was carried out in vitro on L1210 murine leukaemia cell line. The three (+/-)-cis-diol diesters 15, 16, and 18 were the most active compounds. Topics: Acronine; Animals; Antineoplastic Agents; Carbazoles; Cell Line, Tumor; Ellipticines; Leukemia L1210; Mice; Pyrans	2004

Article

Year

Synthesis and cytotoxic activity of pyranocarbazole analogues of ellipticine and acronycine.

Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:5

Various 2,2,5,11-tetramethyl- and 2,2,5,6,11-pentamethyl-2,6-dihydropyrano[3,2-b]carbazole derivatives were synthesized by condensation of 3-methylbut-2-enal or 3-chloro-3-methylbut-1-yne with an appropriate hydroxycarbazole. These compounds associate the tricyclic system responsible for the intercalating properties of ellipticine related drugs, with the dimethylpyran pharmacophore of acronycine derivatives. The study of the biological properties of the new pyrano[3,2-b]carbazole derivatives was carried out in vitro on L1210 murine leukaemia cell line. The three (+/-)-cis-diol diesters 15, 16, and 18 were the most active compounds.

Topics: Acronine; Animals; Antineoplastic Agents; Carbazoles; Cell Line, Tumor; Ellipticines; Leukemia L1210; Mice; Pyrans

2004