acivicin and glycine

acivicin has been researched along with glycine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199020 (83.33)18.7374
1990's4 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ban, M; de Ceaurriz, J1
Abanobi, SE; Laconi, E; Rajalakshmi, S; Rao, PM; Sarma, DS; Vasudevan, S1
Allen, L; Meck, R; Yunis, A1
Ellis, WW; Meck, RA; Reed, DJ1
Griffith, OW; Meister, A1
Allen, LM; Thornthwaite, JT1
Allen, LM; Corrigan, MV; Meinking, T1
Gardell, SJ; Tate, SS2
Kozak, EM; Tate, SS1
Curthoys, NP; Shapiro, RA1
Bernström, K; Hammarström, S; Orning, L1
Aw, TY; Kaplowitz, N; Ookhtens, M1
Bower, SG; Tso, JY; Zalkin, H1
Bruno, S; McGovren, JP; Neil, GL; Penta, J; Poster, DS1
Kizaki, H; Lui, MS; Weber, G1
Chan, PJ; McGovren, JP; Neil, GL; Stewart, JC1
Roberts, J; Rosenfeld, H1
Kufe, DW; Loh, E1
Biles, C; Martin, DG; Mizsak, SA1
Cooney, DA; Kensler, TW; Reck, LJ1
Horiba, M; Kohno, S; Nabe, T; Ohata, K; Saeki, Y; Tanpo, T; Yamamura, H1
Fransvea, E; La Piana, G; Laconi, E; Lofrumento, NE; Marzulli, D; Rajalakshmi, S; Rao, PM; Sarma, DS; Vasudevan, S1
Dringen, R; Hamprecht, B; Pfeiffer, B1

Reviews

1 review(s) available for acivicin and glycine

ArticleYear
Acivicin. An antitumor antibiotic.
    Cancer clinical trials, 1981,Fall, Volume: 4, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Glycine; Humans; Isoxazoles; Neoplasms; Neoplasms, Experimental; Oxazoles

1981

Other Studies

23 other study(ies) available for acivicin and glycine

ArticleYear
Role of gamma-glutamyltranspeptidase and beta-lyase in the nephrotoxicity of hexachloro-1,3-butadiene and methyl mercury in mice.
    Toxicology letters, 1990, Volume: 50, Issue:2-3

    Topics: Acute Kidney Injury; Alkaline Phosphatase; Alkynes; Aminooxyacetic Acid; Animals; Butadienes; gamma-Glutamyltransferase; Glycine; Isoxazoles; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Lyases; Methylmercury Compounds; Mice; Pargyline; Staining and Labeling

1990
Effect of glycine on the induction of orotic aciduria and urinary bladder tumorigenesis in the rat.
    Toxicologic pathology, 1987, Volume: 15, Issue:2

    Topics: Ammonium Chloride; Animals; Aspartic Acid; Cycloheximide; Glycine; Isoxazoles; Male; Orotic Acid; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1987
The inhibition of gamma-glutamyl transpeptidase from human pancreatic carcinoma cells by (alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501).
    Research communications in chemical pathology and pharmacology, 1980, Volume: 27, Issue:1

    Topics: Antibiotics, Antineoplastic; Cells, Cultured; gamma-Glutamyltransferase; Glycine; Half-Life; Humans; Isoxazoles; Oxazoles; Pancreatic Neoplasms; Time Factors

1980
The inhibition of gamma-glutamyl transpeptidase and glutathione metabolism of isolated rat kidney cells by L-(alpha S, 5S)-alpha-amino-3-chloro-4, 5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501).
    Biochemical and biophysical research communications, 1980, Jun-30, Volume: 94, Issue:4

    Topics: Animals; Cells, Cultured; gamma-Glutamyltransferase; Glutathione; Glycine; Isoxazoles; Kidney; Kinetics; Male; Oxazoles; Rats

1980
Excretion of cysteine and gamma-glutamylcysteine moieties in human and experimental animal gamma-glutamyl transpeptidase deficiency.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:6

    Topics: Animals; Autoanalysis; Biological Transport; Cysteine; Dipeptides; Disulfides; gamma-Glutamyltransferase; Glutamates; Glutathione; Glutathione Reductase; Glycine; Humans; Isoxazoles; Male; Mice

1980
The effect of the glutamine analog, AT-125, on the cell cycle of MCF-7 and BT-20 human breast carcinoma cells using DNA flow cytometry.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 29, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line; Cytological Techniques; DNA, Neoplasm; gamma-Glutamyltransferase; Glycine; Humans; Isoxazoles; Oxazoles

1980
Interaction of AT-125, (alpha S,5S)-amino-3-chloro-4,5-dihydroisoxazoleacetic acid, with bovine kidney gamma-glutamyl transpeptidase.
    Chemico-biological interactions, 1981, Volume: 33, Issue:2-3

    Topics: Anilides; Animals; Cattle; gamma-Glutamyltransferase; Glutamates; Glutamine; Glycine; In Vitro Techniques; Isoxazoles; Kidney; Kinetics; Oxazoles

1981
Affinity labeling of gamma-glutamyl transpeptidase by glutamine antagonists. Effects of the gamma-glutamyl transferase and proteinase activities.
    FEBS letters, 1980, Dec-29, Volume: 122, Issue:2

    Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; gamma-Glutamyltransferase; Glycine; Isoxazoles; Kidney; Macromolecular Substances; Oxazoles; Rats; Structure-Activity Relationship

1980
Interaction of the antitumor drug, L-(alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) with renal brush border membranes. Specific labeling of gamma-glutamyl transpeptidase.
    FEBS letters, 1980, Dec-29, Volume: 122, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; gamma-Glutamyltransferase; Glycine; Isoxazoles; Kidney; Male; Microvilli; Molecular Weight; Oxazoles; Rats

1980
Differential effect of AT-125 on rat renal glutaminase activities.
    FEBS letters, 1981, Oct-12, Volume: 133, Issue:1

    Topics: Ammonia; Animals; gamma-Glutamyltransferase; Glutaminase; Glutamine; Glycine; Isoxazoles; Kidney; Kinetics; Male; Oxazoles; Phosphates; Rats

1981
Effects of bile acids and their glycine conjugates on gamma-glutamyl transpeptidase.
    The Journal of biological chemistry, 1983, May-25, Volume: 258, Issue:10

    Topics: Animals; Benzoates; Benzoic Acid; Bile Acids and Salts; Cholic Acids; gamma-Glutamyltransferase; Glycine; Glycocholic Acid; Hippurates; Isoxazoles; Kidney; Rats; Structure-Activity Relationship; Taurocholic Acid

1983
Formation of leukotrienes E3, E4 and E5 in rat basophilic leukemia cells.
    European journal of biochemistry, 1981, Volume: 120, Issue:1

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Basophils; Calcimycin; Chromatography, High Pressure Liquid; Cysteine; Glycine; Isoxazoles; Leukemia, Experimental; Leukotriene E4; Rats; SRS-A

1981
Inhibition of glutathione efflux from isolated rat hepatocytes by methionine.
    The Journal of biological chemistry, 1984, Aug-10, Volume: 259, Issue:15

    Topics: Alkynes; Amino Acids; Animals; Ethionine; Glutathione; Glutathione Disulfide; Glycine; Isoxazoles; Liver; Male; Methionine; Rats; Rats, Inbred Strains; Sodium; Time Factors

1984
Mechanism of inactivation of glutamine amidotransferases by the antitumor drug L-(alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
    The Journal of biological chemistry, 1980, Jul-25, Volume: 255, Issue:14

    Topics: Anthranilate Synthase; Binding, Competitive; Glutamate Synthase; Glutamine; Glycine; Isoxazoles; Kinetics; Nitrogenous Group Transferases; Oxazoles; Serratia marcescens; Transferases

1980
Biochemical pharmacology of acivicin in rat hepatoma cells.
    Biochemical pharmacology, 1982, Nov-01, Volume: 31, Issue:21

    Topics: Animals; Carbon-Nitrogen Ligases; Cell Line; Cell Survival; Cytidine; Deoxycytidine; Deoxyribonucleotides; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Guanosine; Isoxazoles; Ligases; Liver; Liver Neoplasms, Experimental; Oxazoles; Rats; Ribonucleotides

1982
Sex- and age-related mouse toxicity and disposition of the amino acid antitumor agent, acivicin.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 216, Issue:3

    Topics: Age Factors; Animals; Antineoplastic Agents; Female; Glycine; Half-Life; Isoxazoles; Kinetics; Male; Metabolic Clearance Rate; Mice; Oxazoles; Sex Factors; Testosterone; Tissue Distribution

1981
Enhancement of antitumor activity of glutamine antagonists 6-diazo-5-oxo-L-norleucine and acivicin in cell culture by glutaminase-asparaginase.
    Cancer research, 1981, Volume: 41, Issue:4

    Topics: Amidohydrolases; Animals; Asparagine; Azo Compounds; Cell Line; Diazooxonorleucine; DNA; Glutamine; Glycine; Isoxazoles; Kinetics; Leukemia L1210; Mice; Oxazoles; Temperature

1981
Synergistic effects with inhibitors of de novo pyrimidine synthesis, acivicin, and N-(phosphonacetyl)-L-aspartic acid.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Animals; Aspartic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxycytosine Nucleotides; Deoxyribonucleosides; Drug Synergism; Glycine; Isoxazoles; Leukemia L1210; Mice; Organophosphorus Compounds; Orotic Acid; Oxazoles; Phosphonoacetic Acid; Pyrimidines; Ribonucleosides

1981
Derivatization and purification of acivicin (AT-125, U-42,126).
    The Journal of antibiotics, 1981, Volume: 34, Issue:4

    Topics: Antibiotics, Antineoplastic; Antimetabolites; Glycine; Isoxazoles; Oxazoles

1981
Therapeutic effects of acivicin and N-(phosphonacetyl)-L-aspartic acid in a biochemically designed trial against a N-(phosphonacetyl)-L-aspartic acid-resistant variant of the Lewis lung carcinoma.
    Cancer research, 1981, Volume: 41, Issue:3

    Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma; Drug Therapy, Combination; Glycine; Isoxazoles; Ligases; Lung Neoplasms; Neoplasms, Experimental; Organophosphorus Compounds; Oxazoles; Phosphonoacetic Acid; Pyrimidines; Rats

1981
Inhibitory effect of ONO-1078 on specific binding of peptide leukotrienes to human lung crude membrane.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:3

    Topics: Cell Membrane; Chromones; Cysteine; gamma-Glutamyltransferase; Glycine; Humans; Isoxazoles; Leukotriene D4; Lung; Protein Binding; SRS-A

1994
Cycloheximide sensitivity of orotic acid biosynthesis induced by ammonia and glycine administration.
    European journal of biochemistry, 1998, Feb-01, Volume: 251, Issue:3

    Topics: Ammonium Chloride; Animals; Carbamyl Phosphate; Cycloheximide; Dactinomycin; Enzyme Induction; Enzyme Inhibitors; Glycine; Isoxazoles; Kinetics; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Models, Biological; Ornithine Decarboxylase; Orotic Acid; Rats; Rats, Inbred F344

1998
Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jan-15, Volume: 19, Issue:2

    Topics: Animals; Antioxidants; Astrocytes; Cell Survival; Cells, Cultured; Coculture Techniques; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutamine; Glutathione; Glycine; Isoxazoles; Neurons; Rats; Rats, Wistar

1999
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