Page last updated: 2024-08-25

acemannan and mannans

acemannan has been researched along with mannans in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.61)	18.7374
1990's	24 (38.71)	18.2507
2000's	5 (8.06)	29.6817
2010's	24 (38.71)	24.3611
2020's	8 (12.90)	2.80

Authors

Authors	Studies
Baig, MA; Chinnah, AD; Kemp, MC; Tizard, IR	1
Biehle, GA; Bronstad, DC; Ford, CR; Hall, JE; Harris, CK; King, GK; Rosenberg, LJ; Tizard, IR; Walker, B; Yates, KM	1
Balmer, MF; Carpenter, RH; Fogleman, RW; McAnalley, BH; Shellenberger, TE	1
Helderman, JH; Womble, D	2
Carpenter, RH; Chapdelaine, JM; Fogleman, RW; McAnalley, BH	1
Giggleman, GF; Sheets, MA; Tizard, IR; Unger, BA	1
Carpenter, RH; Kahlon, JB; Kemp, MC; McAnalley, BH; Shannon, WM; Yawei, N	1
Tizard, I	1
Carpenter, RH; Kahlon, JB; Kemp, MC; McAnalley, BH; McDaniel, HR; Shannon, WM	1
Hall, J; Harris, C; King, G; Pierce, K; Tizard, I; Yates, KM	1
Busbee, D; Corrier, D; Curtin, G; McDaniel, HR; Norman, J; Peng, SY	1
Karaca, K; Nordgren, R; Sharma, JM	1
Manna, S; McAnalley, BH	1
Arseneau, R; Gill, J; McLean, BD; Montaner, JS; Raboud, J; Ruedy, J; Schechter, MT; Singer, J	1
Kemp, MC; Ramamoorthy, L; Tizard, IR	1
Tizard, IR; Zhang, L	1
Brown, GS; Egger, SF; Kelsey, LS; Rosenberg, LJ; Talmadge, JE; Yates, KM	1
Gelderman, MP; Howard, K; Lefkowitz, DL; Lefkowitz, SS; Lincoln, JA; Stuart, RW	1
Ramamoorthy, L; Tizard, IR	1
Kruth, SA	1
Ford, P; Iacopino, AM; Tello, CG	1
Goode, PS; LaMaster, K; Tennyson, T; Thomas, DR	1
Djeraba, A; Quere, P	1
Han, SS; Kim, JS; Kim, K; Kim, Y; Kim, YS; Lee, CK; Lee, JK; Lee, MK; Yun, YP	1
Hall, JE; Poor, AS; Poor, MR	1
Chavez, J; Chinnah, T; Chow, JT; Jacobs, L; Munger, C; Talmadge, J; Williamson, D; Yates, K	1
Banlunara, W; Jettanacheawchankit, S; Sangvanich, P; Sasithanasate, S; Thunyakitpisal, P	1
Banlunara, W; Jittapiromsak, N; Sahawat, D; Sangvanich, P; Thunyakitpisal, P	1
Darias Martín, J; Díaz Romero, C; Rodríguez Rodríguez, E	1
Güngörmüş, M; Kaya, GŞ; Savaş, Z; Yapici, G	1
Bidra, AS; Chambers, MS; Roberts, DB; Rolston, KV; Tarrand, JJ	1
Bishayee, A; Harlev, E; Lansky, EP; Nevo, E; Ofir, R	1
Bhalang, K; Rungsirisatean, N; Thunyakitpisal, P	1
Banlunara, W; Boonyagul, S; Sangvanich, P; Thunyakitpisal, P	1
Banlunara, W; Chantarawaratit, P; Sangvanich, P; Soontornvipart, K; Thunyakitpisal, P	1
Best, T; Bryan, J; Buckley, J; Howe, P; Scholey, A	1
Castro-Ríos, R; Chávez-Montes, A; González-Horta, A; Lara-Arias, J; Sierra-García, GD	1
Argüelles-Monal, WM; Domard, A; Escobedo-Lozano, AY; Goycoolea, FM; Velázquez, CA	1
Alonso, JL; Gullón, B; Gullón, P; Pintado, M; Tavaria, F	1
Dong, CH; Fu, TT; Guo, W; Huang, H; Li, XY; Li, Z; Qi, JH; Song, J; Xiao, Y; Xing, W; Xu, X; Yuan, PS; Zhu, M; Zou, CH	1
Banlunara, W; Sangvanich, P; Songsiripradubboon, S; Thunyakitpisal, P; Trairatvorakul, C	1
Chokboribal, J; Jettanacheawchankit, S; Ruangpornvisuti, V; Sangvanich, P; Tachaboonyakiat, W; Thunyakitpisal, P	1
Acevedo, AC; Amorim, BR; Costa, CR; De Luca Canto, G; de Magalhães, P; Guerra, EN	1
Chokboribal, J; Kengkwasing, P; Ruangpornvisuti, V; Sangvanich, P; Thunyakitpisal, P	1
Eim, V; Femenia, A; González-Centeno, MR; González-Laredo, RF; Minjares-Fuentes, R; Rodríguez-González, VM	1
Banlunara, W; Kladkaew, S; Sangvanich, P; Songsiripradubboon, S; Soontornvipart, K; Thunyakitpisal, P; Trairatvorakul, C	1
Cardemil, L; Gotteland, M; Quezada, MP; Salinas, C	1
Comas-Serra, F; Femenia, A; Minjares-Fuentes, R; Rodríguez-González, VM	1
Kumar, R; Kumar, S	1
Metcalfe, C	1
Cheng, Y; Cui, Y; Guo, Y; Liu, C; Pi, F; Qian, H	1
Gemignani, F; Iacopetti, I; Martinello, T; Patruno, M; Perazzi, A	1
Alam, MB; Chandrasekharan, A; Chauhan, M; Das, S; Gandhi, S; Ghosh, D; Kaushik, S; Ma, S; Parmar, AS; Santhoshkumar, TR; Sharma, A; Suhag, D	1
Bloomer, RJ; Butawan, M; Keating, FH; van der Merwe, M	1
Fernandes, EM; Reis, RL; Ribeiro, AP; Ribeiro, AR; Rodrigues, LC; Silva, SS	1
Sadgrove, NJ; Simmonds, MSJ	1
Chuenchompoonut, V; Deesricharoenkiat, N; Jansisyanont, P; Mattheos, N; Thunyakitpisal, P	1
Hazari, PP; Mishra, AK; Mittal, P; Sharma, A; Sharma, RK; Yadav, A	1
Chen, J; Cong, F; Du, J; Guo, X; Huang, B; Lao, C; Li, D; Li, J; Li, L; Luo, Y; Tong, X; Xu, W; Ye, H	1

Reviews

9 review(s) available for acemannan and mannans

Article	Year
Use of immunomodulators as an aid to clinical management of feline leukemia virus-infected cats. Journal of the American Veterinary Medical Association, 1991, Nov-15, Volume: 199, Issue:10 Topics: Adjuvants, Immunologic; Animals; Cats; Interferons; Leukemia, Feline; Mannans; Propionibacterium acnes; Staphylococcal Protein A	1991
Biological response modifiers: interferons, interleukins, recombinant products, liposomal products. The Veterinary clinics of North America. Small animal practice, 1998, Volume: 28, Issue:2 Topics: Animals; Antiviral Agents; Cat Diseases; Cats; Communicable Diseases; Dog Diseases; Dogs; Hematopoietic Cell Growth Factors; Humans; Immunologic Factors; Interferons; Interleukins; Liposomes; Mannans; Neoplasms; Recombinant Proteins	1998
Aloe vera as a functional ingredient in foods. Critical reviews in food science and nutrition, 2010, Volume: 50, Issue:4 Topics: Adjuvants, Immunologic; Aloe; Antineoplastic Agents; Antiviral Agents; Consumer Product Safety; Cosmetics; Gastrointestinal Agents; Gels; Humans; Mannans; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Risk Assessment	2010
Anticancer potential of aloes: antioxidant, antiproliferative, and immunostimulatory attributes. Planta medica, 2012, Volume: 78, Issue:9 Topics: Adjuvants, Immunologic; Aloe; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Antioxidants; Emodin; Humans; Mannans; Medicine, Traditional; Plant Extracts; Plant Lectins; Plants, Medicinal	2012
Acemannan, an extracted polysaccharide from Aloe vera: A literature review. Natural product communications, 2014, Volume: 9, Issue:8 Topics: Aloe; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Humans; Mannans; Plant Extracts	2014
Effects of Plants on Osteogenic Differentiation and Mineralization of Periodontal Ligament Cells: A Systematic Review. Phytotherapy research : PTR, 2016, Volume: 30, Issue:4 Topics: Aloe; Cell Differentiation; Cell Proliferation; Centella; Coumarins; Epimedium; Flavonoids; Hesperidin; Humans; Mannans; Morinda; Osteogenesis; Periodontal Ligament; Plant Extracts; Triterpenes; Zanthoxylum	2016
Compositional and Structural Features of the Main Bioactive Polysaccharides Present in the Journal of AOAC International, 2018, Nov-01, Volume: 101, Issue:6 Topics: Aloe; Carbohydrate Sequence; Cellulose; Mannans; Pectins; Rheology; Viscosity; Water	2018
Extraction, Purification, Structural Characteristics, Biological Activities and Pharmacological Applications of Acemannan, a Polysaccharide from Molecules (Basel, Switzerland), 2019, Apr-19, Volume: 24, Issue:8 Topics: Aloe; Animals; Humans; Mannans; Plants, Medicinal; Polysaccharides; Structure-Activity Relationship; Wound Healing	2019
Pharmacodynamics of Aloe vera and acemannan in therapeutic applications for skin, digestion, and immunomodulation. Phytotherapy research : PTR, 2021, Volume: 35, Issue:12 Topics: Aloe; Digestion; Immunomodulation; Mannans; Mannose Receptor; Vaccine Efficacy	2021

Trials

9 trial(s) available for acemannan and mannans

Article	Year
Double-blind placebo-controlled pilot trial of acemannan in advanced human immunodeficiency virus disease. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Jun-01, Volume: 12, Issue:2 Topics: Administration, Oral; Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; HIV Infections; Humans; Male; Mannans; Pilot Projects; Safety; Zidovudine	1996
Acemannan hydrogel dressing versus saline dressing for pressure ulcers. A randomized, controlled trial. Advances in wound care : the journal for prevention and healing, 1998, Volume: 11, Issue:6 Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Bandages; Female; Humans; Hydrogels; Male; Mannans; Middle Aged; Plant Extracts; Pressure Ulcer; Sodium Chloride; Wound Healing	1998
Reduction in the incidence of alveolar osteitis in patients treated with the SaliCept patch, containing Acemannan hydrogel. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2002, Volume: 60, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aloe; Anti-Bacterial Agents; Child; Clindamycin; Dry Socket; Female; Gelatin Sponge, Absorbable; Hemostatics; Humans; Male; Mannans; Middle Aged; Phytotherapy; Plant Extracts; Retrospective Studies; Tooth Extraction; Treatment Outcome	2002
Comparison of alvogyl, SaliCept patch, and low-level laser therapy in the management of alveolar osteitis. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:6 Topics: Adult; Agricultural Irrigation; Aminobenzoates; Bandages; Curettage; Drug Combinations; Dry Socket; Eugenol; Female; Humans; Hydrocarbons, Iodinated; Low-Level Light Therapy; Male; Mannans; Oils, Volatile; Pain Measurement; para-Aminobenzoates; Phytotherapy; Plant Extracts	2011
Acemannan, a polysaccharide extracted from Aloe vera, is effective in the treatment of oral aphthous ulceration. Journal of alternative and complementary medicine (New York, N.Y.), 2013, Volume: 19, Issue:5 Topics: Acrylates; Adjuvants, Immunologic; Administration, Topical; Adult; Aloe; Drug Administration Schedule; Female; Humans; Male; Mannans; Middle Aged; Pain Measurement; Patch Tests; Phytotherapy; Stomatitis, Aphthous; Triamcinolone Acetonide	2013
Acute effects of a dietary non-starch polysaccharide supplement on cognitive performance in healthy middle-aged adults. Nutritional neuroscience, 2015, Volume: 18, Issue:2 Topics: Aging; Cognitive Dysfunction; Cohort Studies; Dietary Supplements; Double-Blind Method; Female; Galactans; Galactose; Glucosamine; Humans; Male; Mannans; Memory, Short-Term; Mental Fatigue; Middle Aged; Nootropic Agents; Performance-Enhancing Substances; Polysaccharides; Recognition, Psychology	2015
Clinical, radiographic, and histologic analysis of the effects of acemannan used in direct pulp capping of human primary teeth: short-term outcomes. Odontology, 2016, Volume: 104, Issue:3 Topics: Calcium Hydroxide; Child; Dental Pulp; Dental Pulp Capping; Female; Humans; Male; Mannans; Molar; Plant Extracts; Pulpitis; Tooth, Deciduous; Treatment Outcome	2016
An Assessment of the Glyconutrient Ambrotose™ on Immunity, Gut Health, and Safety in Men and Women: A Placebo-Controlled, Double-Blind, Randomized Clinical Trial. Nutrients, 2020, Jun-11, Volume: 12, Issue:6 Topics: Adult; Aged; Blood Pressure; Dietary Fiber; Dietary Supplements; Double-Blind Method; Female; Gastrointestinal Microbiome; Healthy Volunteers; Heart Rate; Humans; Immune System; Leukocyte Count; Male; Mannans; Middle Aged; Monocytes; Nutritional Physiological Phenomena; Quality of Life; Young Adult	2020
The effect of acemannan in implant placement with simultaneous guided bone regeneration in the aesthetic zone: a randomized controlled trial. International journal of oral and maxillofacial surgery, 2022, Volume: 51, Issue:4 Topics: Animals; Bone Regeneration; Cattle; Dental Implantation, Endosseous; Dental Implants; Esthetics, Dental; Guided Tissue Regeneration, Periodontal; Humans; Mannans	2022

Other Studies

44 other study(ies) available for acemannan and mannans

Article	Year
Antigen dependent adjuvant activity of a polydispersed beta-(1,4)-linked acetylated mannan (acemannan). Vaccine, 1992, Volume: 10, Issue:8 Topics: Adjuvants, Immunologic; Animals; Antibodies, Viral; Antigens, Viral; Chickens; Infectious bursal disease virus; Mannans; Newcastle disease virus	1992
Pilot study of the effect of acemannan in cats infected with feline immunodeficiency virus. Veterinary immunology and immunopathology, 1992, Volume: 35, Issue:1-2 Topics: Animals; Antiviral Agents; Cats; Feline Acquired Immunodeficiency Syndrome; Female; Immunodeficiency Virus, Feline; Injections, Intravenous; Injections, Subcutaneous; Leukocyte Count; Lymphocytes; Male; Mannans; Neutrophils; Pilot Projects; Random Allocation; Survival Rate	1992
Subchronic oral administration of acemannan in the rat and dog. Veterinary and human toxicology, 1992, Volume: 34, Issue:2 Topics: Administration, Oral; Animals; Antiviral Agents; Body Weight; Dogs; Drug Evaluation; Eating; Female; Male; Mannans; Organ Size; Rats; Rats, Inbred Strains; Stomach	1992
The impact of acemannan on the generation and function of cytotoxic T-lymphocytes. Immunopharmacology and immunotoxicology, 1992, Volume: 14, Issue:1-2 Topics: Adjuvants, Immunologic; Antiviral Agents; Dose-Response Relationship, Drug; Humans; Mannans; T-Lymphocytes, Cytotoxic	1992
Toxicologic evaluation of injectable acemannan in the mouse, rat and dog. Veterinary and human toxicology, 1992, Volume: 34, Issue:3 Topics: Animals; Dogs; Drug Administration Routes; Female; Hematologic Tests; Histocytochemistry; Male; Mannans; Mice; Mice, Inbred Strains; Necrosis; Organ Size; Plant Extracts; Rats; Rats, Inbred Strains	1992
Studies of the effect of acemannan on retrovirus infections: clinical stabilization of feline leukemia virus-infected cats. Molecular biotherapy, 1991, Volume: 3, Issue:1 Topics: Adjuvants, Immunologic; Animals; Cat Diseases; Cats; Injections, Intraperitoneal; Leukemia; Leukemia Virus, Feline; Mannans	1991
In vitro evaluation of the synergistic antiviral effects of acemannan in combination with azidothymidine and acyclovir. Molecular biotherapy, 1991, Volume: 3, Issue:4 Topics: Acyclovir; Drug Synergism; Drug Therapy, Combination; HIV-1; Humans; Mannans; Plant Extracts; Simplexvirus; Tumor Cells, Cultured; Zidovudine	1991
Inhibition of AIDS virus replication by acemannan in vitro. Molecular biotherapy, 1991, Volume: 3, Issue:3 Topics: Antiviral Agents; Cell Line; Cell Survival; Cells, Cultured; Cytopathogenic Effect, Viral; Giant Cells; HIV-1; Humans; Mannans; Virus Replication	1991
Efficacy of acemannan in treatment of canine and feline spontaneous neoplasms. Molecular biotherapy, 1991, Volume: 3, Issue:4 Topics: Adjuvants, Immunologic; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Male; Mannans; Neoplasms; Plant Extracts	1991
Decreased mortality of Norman murine sarcoma in mice treated with the immunomodulator, Acemannan. Molecular biotherapy, 1991, Volume: 3, Issue:2 Topics: Adjuvants, Immunologic; Aloe; Animals; Cytotoxicity, Immunologic; Drug Screening Assays, Antitumor; Female; Lipopolysaccharides; Lymphocyte Activation; Macrophages; Mannans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Monokines; Plant Extracts; Plants, Medicinal; Sarcoma, Experimental; T-Lymphocytes	1991
Enhancement of allo-responsiveness of human lymphocytes by acemannan (Carrisyn). International journal of immunopharmacology, 1988, Volume: 10, Issue:8 Topics: Adjuvants, Immunologic; Animals; Cell Communication; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoantigens; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mannans; Monocytes; Rats; T-Lymphocytes	1988
Nitric oxide production by chicken macrophages activated by Acemannan, a complex carbohydrate extracted from Aloe vera. International journal of immunopharmacology, 1995, Volume: 17, Issue:3 Topics: Adjuvants, Immunologic; Animals; Cell Line; Chickens; Macrophage Activation; Macrophages; Mannans; Nitric Oxide; Plant Extracts; Spleen	1995
Oral ulcers remedy gets FDA clearance. Journal of the American Dental Association (1939), 1994, Volume: 125, Issue:10 Topics: Aloe; Antiviral Agents; Drug Approval; Humans; Mannans; Plant Extracts; Plants, Medicinal; Stomatitis, Aphthous; United States; United States Food and Drug Administration	1994
Determination of the position of the O-acetyl group in a beta-(1-->4)-mannan (acemannan) from Aloe barbardensis Miller. Carbohydrate research, 1993, Mar-17, Volume: 241 Topics: Acetylation; Aloe; Antiviral Agents; Gas Chromatography-Mass Spectrometry; Mannans; Mannosides; Plants, Medicinal	1993
Acemannan, a beta-(1,4)-acetylated mannan, induces nitric oxide production in macrophage cell line RAW 264.7. Molecular pharmacology, 1996, Volume: 50, Issue:4 Topics: Animals; Antioxidants; Cell Line; Cycloheximide; Enzyme Induction; Gene Expression Regulation, Enzymologic; Interferon-gamma; Lipopolysaccharides; Macrophages; Mannans; Mice; Nitric Oxide; Nitric Oxide Synthase; Protein Synthesis Inhibitors; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription, Genetic	1996
Activation of a mouse macrophage cell line by acemannan: the major carbohydrate fraction from Aloe vera gel. Immunopharmacology, 1996, Volume: 35, Issue:2 Topics: Adjuvants, Immunologic; Aloe; Animals; Carbohydrates; Cell Line; Gels; Interferon-gamma; Interleukin-6; Macrophage Activation; Macrophages; Mannans; Membrane Proteins; Mice; Nitric Oxide; Plant Extracts; Plants, Medicinal; Tumor Necrosis Factor-alpha	1996
Hematopoietic augmentation by a beta-(1,4)-linked mannan. Cancer immunology, immunotherapy : CII, 1996, Volume: 43, Issue:4 Topics: Adjuvants, Immunologic; Animals; Blood Cells; Bone Marrow; Bone Marrow Cells; Carbohydrate Conformation; Female; Hematopoiesis; Hematopoietic System; Mannans; Mice; Mice, Inbred C57BL; Spleen; Whole-Body Irradiation	1996
Upregulation of phagocytosis and candidicidal activity of macrophages exposed to the immunostimulant acemannan. International journal of immunopharmacology, 1997, Volume: 19, Issue:2 Topics: Adjuvants, Immunologic; Animals; Candida albicans; Cattle; Female; In Vitro Techniques; Macrophage Activation; Macrophages, Peritoneal; Male; Mannans; Mannose; Mice; Mice, Inbred C57BL; Phagocytosis; Respiratory Burst; Serum Albumin; Up-Regulation	1997
Induction of apoptosis in a macrophage cell line RAW 264.7 by acemannan, a beta-(1,4)-acetylated mannan. Molecular pharmacology, 1998, Volume: 53, Issue:3 Topics: Animals; Antiviral Agents; Apoptosis; Cell Line; Interferon-gamma; Macrophages; Mannans; Mice; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2	1998
In vitro evaluation of complex carbohydrate denture adhesive formulations. Quintessence international (Berlin, Germany : 1985), 1998, Volume: 29, Issue:9 Topics: Adhesiveness; Adhesives; Analysis of Variance; Cells, Cultured; Denture Retention; Evaluation Studies as Topic; Fibroblasts; Gels; Gingiva; Humans; Hydrogen-Ion Concentration; Mannans; Materials Testing	1998
Acemannan. CARN 1000, CARN 750, polymannoacetate, Aliminase, Alovex, Carrisyn. Drugs in R&D, 1999, Volume: 1, Issue:3 Topics: Adjuvants, Immunologic; Animals; Colitis, Ulcerative; Dogs; Drugs, Investigational; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Mannans; Mice; Rats	1999
In vivo macrophage activation in chickens with Acemannan, a complex carbohydrate extracted from Aloe vera. International journal of immunopharmacology, 2000, Volume: 22, Issue:5 Topics: Adjuvants, Immunologic; Animals; Chickens; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Lymphocyte Activation; Macrophage Activation; Mannans; Monocytes; Nitric Oxide	2000
Acemannan purified from Aloe vera induces phenotypic and functional maturation of immature dendritic cells. International immunopharmacology, 2001, Volume: 1, Issue:7 Topics: Adjuvants, Immunologic; Aloe; Bone Marrow Cells; Cells, Cultured; Dendrites; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-12; Lipopolysaccharides; Lymphocyte Culture Test, Mixed; Mannans; Mitogens; Phenotype	2001
Fractionation of Aloe vera L. inner gel, purification and molecular profiling of activity. International immunopharmacology, 2004, Dec-20, Volume: 4, Issue:14 Topics: Aloe; Animals; Biological Factors; Blood Cell Count; Carbohydrate Metabolism; Coculture Techniques; Colony-Forming Units Assay; Cytokines; Female; Hematopoiesis; Hydrogels; Indicators and Reagents; Mannans; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spleen; Stem Cells; Whole-Body Irradiation	2004
Acemannan stimulates gingival fibroblast proliferation; expressions of keratinocyte growth factor-1, vascular endothelial growth factor, and type I collagen; and wound healing. Journal of pharmacological sciences, 2009, Volume: 109, Issue:4 Topics: Aloe; Cell Proliferation; Cells, Cultured; Collagen Type I; DNA; Fibroblast Growth Factor 7; Fibroblasts; Gastrointestinal Agents; Gels; Gingiva; Humans; Mannans; Palate, Hard; Vascular Endothelial Growth Factor A; Wound Healing	2009
Acemannan, an extracted product from Aloe vera, stimulates dental pulp cell proliferation, differentiation, mineralization, and dentin formation. Tissue engineering. Part A, 2010, Volume: 16, Issue:6 Topics: Aloe; Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dental Pulp; Dentin; Humans; Male; Mannans; Rats; Rats, Sprague-Dawley	2010
Antimicrobial efficacy of oral topical agents on microorganisms associated with radiated head and neck cancer patients: an in vitro study. Quintessence international (Berlin, Germany : 1985), 2011, Volume: 42, Issue:4 Topics: Administration, Oral; Anti-Infective Agents, Local; Bacteriological Techniques; Calcium Phosphates; Candida albicans; Chlorhexidine; Escherichia coli; Ethanol; Gels; Head and Neck Neoplasms; Humans; Mannans; Mouth; Mouthwashes; Plant Extracts; Sodium Bicarbonate; Sodium Chloride, Dietary; Solvents; Staphylococcus aureus; Streptococcus agalactiae; Tin Fluorides	2011
Effect of acemannan, an extracted polysaccharide from Aloe vera, on BMSCs proliferation, differentiation, extracellular matrix synthesis, mineralization, and bone formation in a tooth extraction model. Odontology, 2014, Volume: 102, Issue:2 Topics: Aloe; Animals; Bone Density; Bone Development; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Proliferation; Extracellular Matrix; Hematopoietic Stem Cells; Integrin-Binding Sialoprotein; Male; Mannans; Osteopontin; Rats; Rats, Sprague-Dawley; Tooth Extraction	2014
Acemannan sponges stimulate alveolar bone, cementum and periodontal ligament regeneration in a canine class II furcation defect model. Journal of periodontal research, 2014, Volume: 49, Issue:2 Topics: Alkaline Phosphatase; Alveolar Process; Animals; Bone Morphogenetic Protein 2; Bone Regeneration; Calcification, Physiologic; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Cementogenesis; Collagen Type I; Core Binding Factor Alpha 1 Subunit; Dental Cementum; Disease Models, Animal; DNA; Dogs; Furcation Defects; Gels; Growth Differentiation Factor 5; Humans; Mannans; Osteogenesis; Periodontal Ligament; Phytotherapy; Plant Extracts; Regeneration; Vascular Endothelial Growth Factor A	2014
Physical properties and antibacterial activity of chitosan/acemannan mixed systems. Carbohydrate polymers, 2015, Jan-22, Volume: 115 Topics: Anti-Bacterial Agents; Chitosan; Escherichia coli; Mannans; Rheology; Staphylococcus aureus	2015
In vitro assessment of the prebiotic potential of Aloe vera mucilage and its impact on the human microbiota. Food & function, 2015, Volume: 6, Issue:2 Topics: Adult; Aloe; Arabinose; Culture Media; Fatty Acids, Volatile; Feces; Female; Fermentation; Galactose; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; In Situ Hybridization, Fluorescence; Male; Mannans; Mannose; Plant Mucilage; Prebiotics	2015
Acemannan accelerates cell proliferation and skin wound healing through AKT/mTOR signaling pathway. Journal of dermatological science, 2015, Volume: 79, Issue:2 Topics: Adjuvants, Immunologic; Animals; Cell Proliferation; Cells, Cultured; Cyclin D1; Male; Mannans; Mice; Mice, Inbred BALB C; Models, Animal; Oncogene Protein v-akt; Signal Transduction; TOR Serine-Threonine Kinases; Wound Healing	2015
Deacetylation affects the physical properties and bioactivity of acemannan, an extracted polysaccharide from Aloe vera. Carbohydrate polymers, 2015, Nov-20, Volume: 133 Topics: Acetylation; Aloe; Cell Proliferation; Collagen Type I; Gene Expression Regulation; Humans; Hydrophobic and Hydrophilic Interactions; Mannans; Models, Molecular; Molecular Conformation; Physical Phenomena; Solubility; Structure-Activity Relationship; Vascular Endothelial Growth Factor A; Water	2015
Acemannan increases NF-κB/DNA binding and IL-6/-8 expression by selectively binding Toll-like receptor-5 in human gingival fibroblasts. Carbohydrate polymers, 2017, Apr-01, Volume: 161 Topics: Adjuvants, Immunologic; DNA; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Interleukin-6; Interleukin-8; Mannans; NF-kappa B; Protein Binding	2017
Effect of different drying procedures on the bioactive polysaccharide acemannan from Aloe vera (Aloe barbadensis Miller). Carbohydrate polymers, 2017, Jul-15, Volume: 168 Topics: Aloe; Desiccation; Mannans; Polysaccharides	2017
Stimulation of Dentin Regeneration by Using Acemannan in Teeth with Lipopolysaccharide-induced Pulp Inflammation. Journal of endodontics, 2017, Volume: 43, Issue:7 Topics: Alkaline Phosphatase; Blotting, Western; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Cell Proliferation; Collagen Type I; Dental Pulp; Dentin; Humans; In Vitro Techniques; Lipopolysaccharides; Mannans; Pulpitis; Regeneration; Sialoglycoproteins; Vascular Endothelial Growth Factor A	2017
Acemannan and Fructans from Aloe vera (Aloe barbadensis Miller) Plants as Novel Prebiotics. Journal of agricultural and food chemistry, 2017, Nov-22, Volume: 65, Issue:46 Topics: Aloe; Bifidobacterium; Fatty Acids, Volatile; Fermentation; Fructans; Lactobacillus; Mannans; Plant Extracts; Prebiotics	2017
Role of acemannan O-acetyl group in murine radioprotection. Carbohydrate polymers, 2019, Mar-01, Volume: 207 Topics: Acetylation; Aloe; Animals; Apoptosis; Cell Proliferation; Chelating Agents; Free Radical Scavengers; Hematopoiesis; Immunologic Factors; Iron; Male; Mannans; Mice; Molecular Structure; Plant Leaves; Radiation-Protective Agents	2019
Quantitation of Aloe Vera Polysaccharides by O-Acetyl and UV-Vis Spectrophotometry: First Action 2018.14. Journal of AOAC International, 2019, Jul-01, Volume: 102, Issue:4 Topics: Acetylation; Aloe; Coordination Complexes; Iron; Mannans; Spectrophotometry, Ultraviolet	2019
Hyaluronic acid, Manuka honey and Acemannan gel: Wound-specific applications for skin lesions. Research in veterinary science, 2020, Volume: 129 Topics: Animals; Gels; Honey; Hyaluronic Acid; Mannans; Sheep; Sheep Diseases; Skin; Skin Diseases; Wound Healing	2020
Water-Templated, Polysaccharide-rich Bioartificial 3D Microarchitectures as Extra-Cellular Matrix Bioautomatons. ACS applied materials & interfaces, 2020, May-06, Volume: 12, Issue:18 Topics: Acrylates; Antineoplastic Agents; Biomimetic Materials; Camptothecin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Etoposide; Extracellular Matrix; Humans; Hydrogels; Mannans; Methacrylates; Polymerization; Porosity; Reproducibility of Results; Spheroids, Cellular; Tissue Engineering; Tissue Scaffolds	2020
Physicochemical features assessment of acemannan-based ternary blended films for biomedical purposes. Carbohydrate polymers, 2021, Apr-01, Volume: 257 Topics: Alginates; Aloe; Animals; Calorimetry, Differential Scanning; Chitosan; Drug Carriers; Drug Delivery Systems; Hydrogen-Ion Concentration; Mannans; Materials Testing; Membranes, Artificial; Mice; Oscillometry; Plants, Medicinal; Polymers; Polysaccharides; Powders; Rheology; Spectroscopy, Fourier Transform Infrared; Stress, Mechanical; Tissue Engineering; Viscosity	2021
Sustained Activity of Stimuli-Responsive Curcumin and Acemannan Based Hydrogel Patches in Wound Healing. ACS applied bio materials, 2022, 02-21, Volume: 5, Issue:2 Topics: Animals; Curcumin; Hydrogels; Mannans; Mice; Micelles; Poloxamer; Wound Healing	2022
Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism. Carbohydrate polymers, 2022, Dec-01, Volume: 297 Topics: Aloe; Animals; Cytokine Release Syndrome; Cytokines; Glycogen Synthase Kinase 3 beta; Lipopolysaccharides; Macrophages; Mannans; Mice; Phosphatidylinositol 3-Kinases; Plant Extracts; Polysaccharides; Proto-Oncogene Proteins c-akt	2022