Page last updated: 2024-08-26

Mexicanin I and helenalin

Mexicanin I has been researched along with helenalin in 7 studies

*helenalin: toxic principle of Helenium microcephalum (smallhead sneezeweed); structure [MeSH]

*helenalin: toxic principle of Helenium microcephalum (smallhead sneezeweed); structure [MeSH]

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Enriz, RD; Giordano, OS; Guerreiro, E; Guzmán, J; Jáuregui, EA; María, AO; Pestchanker, MJ; Rodríguez, AM; Saad, JR; Wendel, GH1
Beekman, AC; Konings, AW; Pras, N; Schmidt, TJ; van Uden, W; Wikström, HV; Woerdenbag, HJ1
Castro, V; Da Costa, FB; García-Piñeres, AJ; Kisiel, W; Klaas, CA; Merfort, I; Murillo, R; Rüngeler, P; Schulte-Mönting, J; Siedle, B1
Gasteiger, J; Hofmann, A; Merfort, I; Siedle, B; Terfloth, L; Wagner, S1
Emerenciano, VP; Fernandes, MB; Ferreira, MJ; Scotti, MT2
Da Costa, FB; Klempnauer, KH; Schmidt, TJ; Schomburg, C; Schuehly, W1

Other Studies

7 other study(ies) available for Mexicanin I and helenalin

ArticleYear
Structure-activity relationship in the gastric cytoprotective effect of several sesquiterpene lactones.
    Journal of medicinal chemistry, 1992, Jun-26, Volume: 35, Issue:13

    Topics: Lactones; Molecular Conformation; Sesquiterpenes; Stomach; Structure-Activity Relationship

1992
Structure-cytotoxicity relationships of some helenanolide-type sesquiterpene lactones.
    Journal of natural products, 1997, Volume: 60, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Chromatography, High Pressure Liquid; Computer Simulation; Drug Screening Assays, Antitumor; Lactones; Mice; Models, Structural; Molecular Conformation; Sesquiterpenes; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1997
Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-kappaB.
    Journal of medicinal chemistry, 2004, Nov-18, Volume: 47, Issue:24

    Topics: Electrophoretic Mobility Shift Assay; Humans; Jurkat Cells; Lactones; Models, Molecular; NF-kappa B; Quantitative Structure-Activity Relationship; Regression Analysis; Sesquiterpenes

2004
Development of a structural model for NF-kappaB inhibition of sesquiterpene lactones using self-organizing neural networks.
    Journal of medicinal chemistry, 2006, Apr-06, Volume: 49, Issue:7

    Topics: Lactones; Models, Molecular; Neural Networks, Computer; NF-kappa B; Quantitative Structure-Activity Relationship; Sesquiterpenes

2006
Quantitative structure-activity relationship of sesquiterpene lactones with cytotoxic activity.
    Bioorganic & medicinal chemistry, 2007, Apr-15, Volume: 15, Issue:8

    Topics: Algorithms; Antineoplastic Agents, Phytogenic; Artificial Intelligence; Asteraceae; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Humans; Models, Statistical; Neoplasms; Quantitative Structure-Activity Relationship; Regression Analysis; Sesquiterpenes; Structure-Activity Relationship

2007
Use of self-organizing maps and molecular descriptors to predict the cytotoxic activity of sesquiterpene lactones.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:10

    Topics: Antineoplastic Agents; Drug Evaluation, Preclinical; Humans; Lactones; Neural Networks, Computer; Sesquiterpenes

2008
Natural sesquiterpene lactones as inhibitors of Myb-dependent gene expression: structure-activity relationships.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Acetyltransferases; Animals; Cell Line; Cell Survival; Chickens; Computer Simulation; Dose-Response Relationship, Drug; Gene Expression; Green Fluorescent Proteins; Inhibitory Concentration 50; Lactones; Models, Molecular; Molecular Conformation; Molecular Structure; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myb; Sesquiterpenes; Structure-Activity Relationship

2013