Page last updated: 2024-08-17

17-alpha-hydroxyprogesterone and spironolactone

17-alpha-hydroxyprogesterone has been researched along with spironolactone in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's3 (23.08)18.2507
2000's5 (38.46)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Bellavance, E; Luu-The, V; Poirier, D1
Lewicka, S; Vecsei, P; Weindel, K1
Contreras, P; Rojas, A; Vega, I1
Tremblay, RR1
Biffignandi, P; Molinatti, GM1
Lobo, RA; Serafini, P1
Felber, JP; Locatelli, L; Ramelet, AA; Rey, FO; Valterio, C1
Durmuşoğlu, F; Erenus, M; Gürbüz, O; Pekin, S; Yücelten, D1
Arai, J; Ichihara, N; Kobayashi, K; Terai, I; Yamano, K1
Lumachi, F; Rondinone, R1
Guzelmeric, K; Seker, N; Turan, C; Unal, O1

Reviews

1 review(s) available for 17-alpha-hydroxyprogesterone and spironolactone

ArticleYear
Treatment of hirsutism with spironolactone.
    Clinics in endocrinology and metabolism, 1986, Volume: 15, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hirsutism; Humans; Hydroxyprogesterones; Kinetics; Menstrual Cycle; Receptors, Androgen; Sex Hormone-Binding Globulin; Spironolactone; Testosterone

1986

Trials

4 trial(s) available for 17-alpha-hydroxyprogesterone and spironolactone

ArticleYear
Antiandrogens and hirsutism.
    Hormone research, 1987, Volume: 28, Issue:2-4

    Topics: 17-alpha-Hydroxyprogesterone; Adult; Androgen Antagonists; Clinical Trials as Topic; Cyproterone; Cyproterone Acetate; Drug Therapy, Combination; Estradiol; Ethinyl Estradiol; Female; Hirsutism; Humans; Hydroxyprogesterones; Prolactin; Spironolactone; Testosterone

1987
Lack of endocrine systemic side effects after topical application of spironolactone in man.
    Journal of endocrinological investigation, 1988, Volume: 11, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Administration, Topical; Adult; Androgens; Androstane-3,17-diol; Canrenone; Endocrine Glands; Humans; Hydroxyprogesterones; Male; Salivary Glands; Spironolactone; Testosterone

1988
Comparison of spironolactone-oral contraceptive versus cyproterone acetate-estrogen regimens in the treatment of hirsutism.
    Fertility and sterility, 1996, Volume: 66, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Contraceptives, Oral, Synthetic; Cyproterone Acetate; Desogestrel; Drug Therapy, Combination; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; Hirsutism; Humans; Hydroxyprogesterones; Luteinizing Hormone; Mineralocorticoid Receptor Antagonists; Progesterone Congeners; Prospective Studies; Single-Blind Method; Spironolactone; Testosterone

1996
Use of cyproterone acetate, finasteride, and spironolactone to treat idiopathic hirsutism.
    Fertility and sterility, 2003, Volume: 79, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androgen Antagonists; Androstenedione; Cyproterone Acetate; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Female; Finasteride; Hirsutism; Humans; Prospective Studies; Spironolactone; Testosterone

2003

Other Studies

8 other study(ies) available for 17-alpha-hydroxyprogesterone and spironolactone

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
Interference of C17-spirosteroids with late steps of aldosterone biosynthesis. Structure-activity studies.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:10

    Topics: 17-alpha-Hydroxyprogesterone; 18-Hydroxycorticosterone; Aldosterone; Animals; Corticosterone; Depression, Chemical; Hydroxyprogesterones; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Spironolactone; Structure-Activity Relationship

1991
[Adrenal hyperplasia of late onset: optimization of therapy by measuring the circadian variation of serum 17-OH-progesterone].
    Revista medica de Chile, 1989, Volume: 116, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adult; Circadian Rhythm; Dexamethasone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Spironolactone

1989
The effects of spironolactone on adrenal steroidogenesis in hirsute women.
    Fertility and sterility, 1985, Volume: 44, Issue:5

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgens; Androstenedione; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Spironolactone; Steroids; Time Factors

1985
Influence of spironolactone on neonatal screening for congenital adrenal hyperplasia.
    Archives of disease in childhood. Fetal and neonatal edition, 1999, Volume: 81, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Diuretics; Enzyme-Linked Immunosorbent Assay; False Positive Reactions; Humans; Infant, Newborn; Male; Neonatal Screening; Spironolactone

1999
High serum prostate-specific antigen concentrations in hirsute women do not decrease with treatment by the combination of spironolactone and the contraceptive pill.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 19, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adult; Biomarkers; Body Mass Index; Contraceptives, Oral; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Hirsutism; Humans; Norpregnenes; Prostate-Specific Antigen; Spironolactone; Testosterone

2004
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