Page last updated: 2024-09-27

Developmental Dysplasia of the Hip

Dislocation of the HIP JOINT from an abnormal FEMORAL HEAD to the ACETABULUM relationship. It is most often due to ligamentous laxity, abnormal positioning of the joint and various other developmental, congenital factors, and method of delivery (e.g., OLIGOHYDRAMNIOS). When dislocation is diagnosed in neonates it is referred to as CONGENITAL HIP DYSPLASIA.

Synonyms(4)

Synonym
Developmental Dysplasia of the Hip
Developmental Hip Dislocation
Developmental Hip Dysplasia
Hip Dislocation, Developmental

Research Excerpts

Treatment

ExcerptReference
"It is challenging to treat developmental dysplasia of the hip (DDH) classified Crowe III-IV using direct anterior approach (DAA) total hip arthroplasty (THA), and very little is known on its outcome."( Bell, CD; Li, J; Liu, Z; Ong, AC; Zhang, J; Zhang, Y, 2021)

Research

Studies (9)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's0 (0.00)28.8240
2020's9 (100.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
benzene0low10
gadolinium 1,4,7,10-tetraazacyclododecane-n,n',n'',n'''-tetraacetate0low10
gadolinium dtpa0low10

Protein Targets (20)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Integrase0101
Chain A, Integrase0101
Chain A, T4 LYSOZYME0011
Chain A, GCN4P10011
Chain B, GCN4P10011
Chain C, GCN4P10011
Chain A, T4 LYSOZYME0011
Chain A, T4 LYSOZYME0011
Chain A, Replicase polyprotein 1ab0101
Chain A, 3C-like proteinase0101
pregnane X receptor1001
thyroid stimulating hormone receptor1001
progesterone receptor1001
retinoid X nuclear receptor alpha1001
peroxisome proliferator-activated receptor delta1001
cellular tumor antigen p53 isoform a1001
Endolysin0011
Cellular tumor antigen p531001
Integrin beta-31001
Integrin alpha-IIb1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]