Page last updated: 2024-09-27

Aphasia, Associative

A type of fluent aphasia characterized by an impaired ability to repeat one and two word phrases, despite retained comprehension. This condition is associated with dominant hemisphere lesions involving the arcuate fasciculus (a white matter projection between Broca's and Wernicke's areas) and adjacent structures. Like patients with Wernicke aphasia (APHASIA, WERNICKE), patients with conduction aphasia are fluent but commit paraphasic errors during attempts at written and oral forms of communication. (From Adams et al., Principles of Neurology, 6th ed, p482; Brain & Bannister, Clinical Neurology, 7th ed, p142; Kandel et al., Principles of Neural Science, 3d ed, p848)

Synonyms(6)

Synonym
Aphasia, Conduction
Dysphasia, Conduction
Associative Dysphasia
Dysphasia, Associative
Associative Aphasia
Aphasia, Associative

Research

Studies (2)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's1 (50.00)12.5806
2000's1 (50.00)18.1394
2010's0 (0.00)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
inositol 3-phosphate0low10
technetium tc 99m exametazime0low10
jaw0low10

Protein Targets (4)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
ATAD5 protein, partial1001
estrogen-related nuclear receptor alpha1001
Chymotrypsinogen A0101
ATP-dependent phosphofructokinase1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]