verucopeptin: structure given in first source; isolated from Actinomadura verrucosospora; 19-membered cyclodepsipeptide [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 121231434 |
| MeSH ID | M0219632 |
| Synonym |
|---|
| verucopeptin |
| 2xj0d6e0xc , |
| 138067-14-8 |
| glycine, 3-hydroxy-n-(2-hydroxy-1-oxo-2-(tetrahydro-2-hydroxy-5-methoxy-6-(1,3,5,7-tetramethyl-1-nonenyl)-2h-pyran-2-yl)propyl)leucylhexahydro-3-pyridazinecarbonyl-n-hydroxyglycyl-n-methylglycylglycyl-n-methyl-, rho-lactone |
| unii-2xj0d6e0xc |
| bu-3983t |
| verucopeptin, (-)- |
| glycine, 3-hydroxy-n-(2-hydroxy-1-oxo-2-(tetrahydro-2-hydroxy-5-methoxy-6-(1,3,5,7-tetramethyl-1-nonenyl)-2h-pyran-2-yl)propyl)leucylhexahydro-3-pyridazinecarbonyl-n-hydroxyglycyl-n-methylglycylglycyl-n-methyl-, .rho.-lactone |
| bmy-28782 |
| Q27255768 |
| HY-P2657 |
| CS-0137644 |
| DTXSID701043987 |
Verucopeptin is an inhibitor of hypoxia-inducible factor 1 (HIF-1), which is a promising target for cancer chemotherapy.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Verucopeptin is an inhibitor of hypoxia-inducible factor 1 (HIF-1), which is a promising target for cancer chemotherapy. " | ( Total synthesis of verucopeptin, an inhibitor of hypoxia-inducible factor 1 (HIF-1). Hayashi, H; Kakeya, H; Poznaks, V; Takahashi, N, 2019) | 2.29 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||